74 results about "Optical engineering" patented technology

The invention relates to a multi-agent large model code generation method and system in the optical field, relates to the technical field of optical design, and aims to solve the technical problems that in the prior art, optical terminologies are insufficiently understood, and optical performance requirements and constraints cannot be correctly extracted. The optical field multi-agent large model code generation system comprises a demand understanding agent, an optical expert agent, an architecture design agent, a script generation module, a test and feedback module, a control scheduling module and an output module. According to the multi-agent large model code generation method and system in the optical field, the accuracy of understanding optical professional requirements is greatly improved; the capability of automatically generating optical software scripts such as Zemax is higher; multiple rounds of test feedback and control scheduling are supported, and the generation accuracy is improved; the overall development period is shortened, and the optical modeling efficiency is higher; the method is more friendly to non-professional users, and the operation threshold is reduced; and the dependence on qualified optical engineers is reduced, and the development cost is reduced.

The invention belongs to the technical field of optical engineering, and discloses a tree real skeleton point extraction method and system based on a deep neural network and a minimum spanning tree algorithm, a terminal and a storage medium, and the method comprises the steps: obtaining original point cloud data; predicting the original point cloud data based on a deep neural network, and obtaining the vector, radius and category information of each point cloud; performing centralization processing on the original point cloud data according to the vector, radius and category information of each point cloud, and performing initial skeleton extraction by using a minimum spanning tree algorithm to obtain initial skeleton points; simplifying and smoothing the initial skeleton point, and updating to obtain a real skeleton point based on a real skeleton point updating method of Euclidean clustering; and outputting the real skeleton point. The tree real skeleton point extraction precision is improved, and the reconstruction precision of the tree model is improved.

The invention discloses an intelligent street lamp three-dimensional advertisement interaction system and method based on a DCT-plate coupling technology, and relates to the technical field of optical engineering and material science. Real-time compression and feature extraction of advertisement data are achieved through the signal processing module, a deformable microprism array in the light field reconstruction unit is driven, and dynamic three-dimensional advertisement display is achieved in combination with an electrochromic film; the environment sensing module collects illumination, temperature and humidity and space target information, and the control center optimizes driving parameters according to the information, compensates environment interference and guarantees imaging quality. The interactive interface supports gesture recognition and NFC communication, intelligent interactive updating of advertisement content is achieved, and the information service efficiency and user experience of the urban public space are improved.

This invention concerns a remarkable method of an integration of Quantum Dots in optoelectronic devices in for including embedding quantum dots (metallic, inorganic or colloidal) within different layers of the multilayer structure of the emerging thin film optoelectronic devices such as Organic Photovoltaics - OPVs, Perovskite Photovoltaics - PPVs, Organic Light Emitting Diodes - OLEDs to achieve higher performance and subsequently deploying these improved flexible and lightweight devices in Agriculture notably Greenhouses, Open Field Cultivations, Breeding, as well as notably Glass Buildings, UV Health-care protection. This invention promotes the enhancement of power conversion efficiency of semitransparent OPV panels and desirable properties of optoelectronic devices as well as the enhancement of crop production more than 30%. This phenomenon is attributed to a combination of factors: the shading effect generated by OPV panels and an even bigger enhancement as a result of the incorporation of quantum dots within a nanolayer of the multilayer structure of an optoelectronic device. These quantum dots, acting as additives in solutions, are printed onto a substrate and have the ability to achieve optical engineering and optical tuning by controlling the solar spectrum that penetrates through optoelectronic devices, thus the manipulation of absorption across a range of wavelengths, including far UV, UV, and even less beneficial visible wavelengths, is realized. Consequently, these wavelengths are efficiently converted into more advantageous blue and red wavelengths for agricultural applications, or even in any preferable wavelength of the visible spectrum in applications such as glass buildings.

The invention discloses a light field time domain super-resolution method based on an event camera, and belongs to the field of optical engineering. A light field camera and an event camera are used for collecting light field event data, decoding the light field data, denoising the event data and generating an event image, the light field data and an event grayscale image are subjected to joint calibration in a sub-aperture image mode, joint optimization is carried out through calibration results of multiple viewpoints, a checkerboard is shot, and a target object is obtained. And obtaining an affine transformation matrix and a perspective transformation matrix, and obtaining a super-resolution result of projecting the event image onto a light field image plane. Starting from the expression mode of the light field macro pixel, the method has applicability to light field data of any macro pixel size; compared with a traditional time domain super-resolution method, the time domain super-resolution of the light field camera at any frame rate can be realized by segmenting the event stream at different scales.

A kind of multi-wavelength selection laser based on Ho doped crystal and its wavelength tuning method belong to the field of optoelectronic device manufacturing and optical engineering laser technology.To solve the function of multi-wavelength output of multi-wavelength selection laser, the pump source of 1940nm is connected with fiber coupler through fiber, the fiber coupler is arranged with fiber coupling lens group, polaroid, input plane mirror, Ho doped mixed crystal, output plane mirror and 1900nm narrow band filter in sequence along the light path;The Ho doped mixed crystal is composed of first square doped crystal, second square doped crystal, third square doped crystal and fourth square doped crystal, and the combination includes Ho: LLF crystal, Ho: YAP crystal and Ho: YLF crystal cut in different axial directions.The present application can efficiently realize tunable multi-wavelength output.By combining Ho doped crystals with different substrates, a laser is used to realize multi-wavelength output in a wide wavelength range.

The invention relates to the technical field of optical engineering, and discloses a multispectral fusion optical coherence tomography imaging method, which adopts a multispectral light source to cooperatively collect OCT signals, fully utilizes the absorption / scattering characteristic difference of different spectrums on different components of a sample, obtains richer sample structure and component information, and improves the imaging accuracy. A data basis is provided for follow-up accurate identification of sample components, synchronism and wavelength accuracy of multispectral signals are ensured through synchronous driving control and accurate spectrum calibration, and information distortion caused by spectrum deviation is avoided; a registration algorithm based on SIFT feature point matching is adopted, high-precision spatial alignment of multispectral OCT images is achieved, the problem of dislocation between different spectral images is solved, the whole imaging process gives consideration to imaging efficiency and imaging quality, the imaging time is shortened through a synchronous collection mode, the method is suitable for dynamic sample imaging, parameter adjustability of all modules is high, and the method is easy to implement. Flexible adjustment can be performed according to different sample characteristics, and the application range of the method is expanded.

The application discloses a mirror shape preserving optical bench structure cross-scale optimization design method and device, and relates to the technical field of optical engineering. The method comprises the following steps: in the offline stage, parameterized point array modeling and equivalent performance prediction are carried out, and a prediction model is established. In the online stage, the optical bench structure is selected, the design domain is determined and the finite element is discretized, then the entity and point array areas are divided, the load and boundary conditions are applied, and the design variables are defined. The prediction model is called to obtain the point array mechanical performance to calculate the structure strain energy, the mirror node displacement is extracted, and the mirror surface shape information is obtained by fitting. An optimization model is established with the minimum structure strain energy as the objective function and the mirror surface shape information as the constraint, and optimization iteration is carried out with the aid of sensitivity information. If the optimization model does not converge, the design variables are adjusted, the constraints are redefined, and the iteration is continued. If the optimization model converges, the optical bench cross-scale shape preserving optimization result is obtained. The method solves the problem that the traditional design method cannot meet the demand of a new generation of optical mechanical system in terms of light weight, stiffness and mirror shape preservation.

This application provides a quantum optical microcavity device modified with fluorinated organophosphonic acid and its fabrication method, relating to the fields of organic chemistry and optical engineering. The quantum optical microcavity device includes a microcavity body and a fluorinated organophosphonic acid monolayer attached to the surface of the microcavity body. A hydrophobic fluorinated organophosphonic acid monolayer is formed on the surface of the microcavity body through a chemical reaction between a mixed solution containing fluorinated organophosphonic acid molecules and the surface of the microcavity body. Since the active head groups of the fluorinated organophosphonic acid can form chemical bonds with –OH and Si–O–Si on the surface of silica through reaction, the adsorption of water molecules from the air onto the –OH and Si–O–Si on the surface of the silica microcavity body can be effectively suppressed, thus improving the Q-value stability of the whispering-gallery mode quantum optical microcavity device.

This invention belongs to the field of optical engineering and intelligent temperature control technology, and provides a thermal control device and method for a plane mirror. The device consists of an adjustment component, a clamping component, a thermal control component, an optical element, and a temperature measuring component. The optical element is mounted on the surface of the adjustment component via the clamping component. The surface of the optical element is divided into several independent regions, and each region is equipped with a corresponding thermal control component. The temperature measuring component can monitor the temperature of the optical element. The device of this invention divides the optical element into several regions and configures a thermal control component for each region. Each thermal control component includes a water-cooling pipe and a heating resistor. The water-cooling pipe can exchange heat with the corresponding region of the optical element to achieve cooling, while the heating resistor can heat the optical element. The two work together in the corresponding region of the optical element to perform targeted temperature regulation, ultimately maintaining the overall temperature of the optical element within a certain range, thereby effectively improving the problem of surface shape changes.

This invention relates to a tunable spatially multiplexed multi-wavelength laser based on Ho:LLF and a wavelength tuning method, belonging to the field of optoelectronic device manufacturing and optical engineering laser technology. To achieve multiple selectable wavelength outputs in the tunable spatially multiplexed multi-wavelength laser, the 1940nm pump source is connected to a fiber-coupled lens group via an optical fiber. Along the optical path on the right side of the fiber-coupled lens group, a microlens array, a polarizer group, an input plane mirror, a c-axis-cut Ho:LLF crystal, an output plane mirror, a 1900nm narrowband filter, and a set of polarizing beam-splitting prisms are arranged sequentially. The rotation angle of the polarizer group is set to a gradient change from 0° to 90°. The surface of the input plane mirror is coated with a 2050nm narrowband reflective film, and the surface of the output plane mirror is coated with a 2050nm 5% transmission film. The c-axis-cut Ho:LLF crystal is cuboid in shape. This invention realizes the design of a miniaturized multi-wavelength laser.

The invention provides a multiband light source device, and relates to the field of optical engineering. The device comprises a multicolor LED module, an LD light source module and a switching module, the LD light source module comprises a laser light source and a fluorescent sheet, and the laser light source is used for emitting laser to irradiate the fluorescent sheet so as to output exciting light; the fluorescent sheet is integrated on the switching module, the switching module is used for switching two working states of the multiband light source device, and in the first working state, the multicolor LED module outputs emitted light with different wavelengths; and in the second working state, the LD light source module outputs exciting light. The LD light source module effectively makes up the defects of the multi-color LED module in the aspect of optical power, and state switching between multi-wavelength emission light of the multi-color LED module and high-power excitation light of the LD light source module is achieved by means of the switching module.

The invention discloses an optical bench structure cross-scale optimization design method and device considering mirror surface shape preservation, and relates to the technical field of optical engineering. Comprising the following steps: performing parameterized dot matrix modeling and equivalent performance prediction in an offline stage, and establishing a prediction model; in the online stage, an optical bench structure is selected, a design domain is determined, finite element discretization is carried out, entity and dot matrix areas are divided, loads and boundary conditions are applied, and design variables are defined. And calling the prediction model to obtain dot matrix mechanical properties so as to calculate structural strain energy, extracting mirror surface node displacement, and fitting to obtain mirror surface shape information. And establishing an optimization model by taking the minimum structural strain energy as an objective function and the mirror surface shape information as constraints, and performing optimization iteration by means of sensitivity information. And if the optimization model is not converged, adjusting the design variable, redefining the constraint to continue iteration, and if the optimization model is converged, obtaining a cross-scale conformal optimization result of the optical bench. The problem that a traditional design method is difficult to meet the requirements of a new-generation optical-mechanical system in the aspects of light weight, rigidity, mirror surface shape preservation and the like is solved.

The present application relates to an ultrasonic intelligent nondestructive testing method based on pose adjustment of a probabilistic convolutional neural network, and belongs to the technical fields of mechanical engineering, optical engineering, nondestructive testing and automated detection. The method comprises the following steps: initializing ultrasonic testing parameters; generating a standard scanning path for a mechanical arm; pre-processing ultrasonic waveform signals; ultrasonic imaging and defect identification using a probabilistic convolutional neural network; inputting the ultrasonic imaging results into the probabilistic convolutional neural network for defect identification processing, to obtain a classification result of the presence or absence of a defect, a corresponding predicted uncertainty of the defect and defect size information; and determining the classification result of the presence or absence of a defect and the corresponding predicted uncertainty output by the probabilistic convolutional neural network. By introducing a deep learning model to predict the uncertainty as an online feedback quantity, a scanning control mechanism based on uncertainty determination is established, so that the detection process can dynamically adjust the scanning path and the probe pose according to the reliability of the identification result.

A highlight element simulation optimization method and device, an electronic device and a storage medium relate to the technical field of optical engineering and digital twinning, and the method comprises the following steps: obtaining a performance index of a highlight element, and performing simulation analysis by using optical analysis software to obtain parameter information, and a sensor network is arranged around the element to collect thermal field data in real time. Based on the data, a digital twinborn model of the highlight element is constructed, dynamic simulation of the working process of the highlight element is realized, and surface precision data is obtained. And in combination with a preset surface precision threshold, a dynamic compensation strategy and optimization parameters are formulated, and real-time dynamic adjustment is carried out on the strong light element. The attitude and position of the element are accurately controlled through the six-degree-of-freedom parallel mechanism, and the surface precision is ensured to meet the design requirement. The problems that in the prior art, surface type changes in the working process are difficult to reflect in real time, full life cycle evaluation and closed loop feedback mechanisms are lacked, dynamic optimization cannot be achieved, the system performance is unstable, and the optimization effect is limited are solved.

The invention relates to the technical field of optical engineering, and discloses a handheld laser directional energy system which comprises a Shack-Hartmann wavefront detection system, a visual observation system, an atmospheric turbulence correction system, a laser emission system, a laser ranging system and an anti-shake system. By integrating wavefront detection and adaptive correction, coaxial design, target background difference enhancement through light splitting, MEMS reflector dynamic adjustment, jitter compensation and other technologies, the problems that the imaging quality is interfered by atmospheric turbulence, correction is inaccurate due to system space separation, the contrast ratio of a dark and weak target is poor, aiming is difficult, and jitter miss is caused are solved; the effects of high-resolution imaging, energy concentration, easy target discovery, automatic locking and stable aiming are achieved.

The invention discloses a metasurface integrated structured light emission system and a light beam regulation and control method, and relates to the technical field of optical engineering.The metasurface integrated structured light emission system comprises a protection sleeve box, a laser chip body is installed on the inner wall of the protection sleeve box, and a miniature isolator is installed at the output end of the laser chip body; one end of the miniature isolator is provided with a collimating lens group, two sides of the miniature isolator and the collimating lens group are respectively provided with a fixing assembly, and one end of the collimating lens group is provided with an optical lens cone; according to the metasurface integrated structured light emission system and the light beam regulation and control method, through the arrangement of the protection sleeve box, the laser chip main body, the micro isolator, the collimating lens group, the fixing assembly and the optical lens cone, a traditional complex discrete optical system is integrated into an integrally packaged and plug-and-play independent module; the problems that in the prior art, the size is large, installation and adjustment are difficult, and environmental adaptability is poor are effectively solved, and a reliable hardware platform is provided for the structured light technology from a laboratory to engineering application.

The invention relates to the technical field of optical engineering, and particularly discloses a multiband coaxial radiation composite lighting assembly. Comprising a lens barrel and a composite base communicated through an inner cavity. One end of the lens barrel is provided with an optical fiber head for introducing laser which is amplified by first and second internal lenses; a first light passing opening and a second light passing opening in the composite base are provided with an LED assembly (a visible light source) and heating glass (generating infrared radiation) respectively, laser, visible light and infrared radiation are refracted into coaxial composite light beams through a refraction lens in an inner cavity, the coaxial composite light beams are output through the heating glass, and the visible light and the laser can be transmitted through the heating glass. The assembly solves the problems that a multi-band light source is difficult to output coaxially, the test adaptability is insufficient, maintenance and adjustment are inconvenient and the energy transmission compatibility is poor, multi-band coaxial radiation is achieved, the function of a photoelectric detection device and the performance test process of coaxiality and the like are simplified, the test efficiency and precision are improved, and the test cost is reduced. And meanwhile, good adaptability, maintainability and stability are achieved.

The utility model provides a spatial optical coupling structure, which belongs to the technical field of spectral analysis and optical engineering and comprises a bearing mechanism, a lens cone, a base connected with an inner cavity of the lens cone through a jackscrew and a transverse dovetail fixedly connected with the base through a dovetail structure. And the focusing lens group comprises a lens frame which is movably arranged in the inner cavity of the lens barrel. By means of the optimized design of the structure, space incident light can be efficiently coupled into the optical fiber, and the optical fiber coupling device is suitable for optical equipment such as a microscopic Raman spectrometer detection system. The coupling efficiency of spatial light to optical fibers is improved, the transmission quality of optical signals is improved, and the optical fiber coupler is compact in structure, easy to integrate into an optical system and suitable for complex optical path design; through accurate optical element layout, reflection and scattering of light are reduced, and the quality of light beams is improved; the method is suitable for various application scenes, such as the fields of optical communication, spectral analysis and the like, and has relatively high universality and practicability.

The application relates to the technical field of optical engineering, and discloses a photoetching precision measuring device and a method for improving photoetching precision, which comprises a supporting frame, a mounting frame is fixedly connected to the top right side of the supporting frame, a protection plate is fixedly connected to the inner side of the mounting frame, two guide rods are fixedly connected to the inside of the protection plate, a reset spring is arranged on the outside of the guide rods, two movable plates are slidably connected to the outside of the guide rods, two traction rods are rotatably connected to the bottom of the movable plates, and a fixed plate is rotatably connected to the bottom end of the traction rods. The step motor, the rotating disc, the driving block, the swing plate, the rotating shaft, the sector gear and the rack plate are used in combination, so that dust on the surface of a test probe can be automatically blown off, the surface of the test probe can be kept clean, scattering or absorption of the dust on the light beam is prevented, and the measurement accuracy and stability are maintained.

The invention discloses a multi-virtual image generation system based on dual-channel optical path multiplexing and a ciliary muscle training device, and relates to the technical field of optical engineering and ophthalmology medical instruments. The device comprises a near-far field double-image generation unit, a light beam combination element, a focal power modulation element and a precise control module, double virtual images with preset diopter difference are generated by optimizing optical parameter design, electronic switching logic and a dynamic positioning mechanism, crystalline lenses are forced to generate physical deformation, and physiologically effective ciliary muscle training is achieved. The light path folding and polarization / amplitude segmentation technology is adopted, the light rays of the two independent image sources are projected to the same visual axis of the human eyes, far and near alternate adjustment stimulation is formed, the training efficiency is improved, and the service life of the device is prolonged.

The invention provides a high-color-gamut peep-proof film surface stress distribution and optical performance cooperative control method, which relates to the technical field of optical engineering, and comprises the following steps: acquiring peep-proof film multilayer structure data, establishing a feature set, forming a cooperative representation vector by using deep neural network joint coding, and generating a cooperative control strategy based on a bidirectional influence weight matrix. And making a process parameter adjustment scheme. According to the invention, collaborative optimization of stress regulation and optical performance is realized, the color rendition degree and visual angle control precision of the peep-proof film are improved, and the service life of the product is prolonged.

The invention discloses a privacy protection camera based on an optical engineering scattering sheet and a privacy protection method thereof.The privacy protection camera comprises a camera module, the camera module is provided with the engineering scattering sheet, the engineering scattering sheet is made of POG materials, the divergence angle of the engineering scattering sheet is 1 + / -0.5 degrees, the light transmittance of the engineering scattering sheet is larger than 85%, and the light transmittance of the engineering scattering sheet is larger than 90%. The POG material comprises a glass substrate and surface polymer micro-lens array layers, the surface polymer micro-lens array layers are randomly distributed, and the height difference is 0-2 [mu] m; according to the invention, no complex algorithm is needed, sensitive detail blurring is realized through optical regulation and control of the engineering scattering sheet, and the cracking difficulty is far higher than that of a digital algorithm; through controllable scattering, only details are fuzzy, and overall contour and action recognition is not affected; the circular defocused spots ensure uniform diffusion of facial details, the diffusion angle is controllable, and privacy and recognition requirements can be balanced; the POG material structure combines the high stability of the glass and the microstructure precision of the polymer, the light transmittance is greater than 85% and is better than that of ground glass which is less than 70%, and the glass has no deformation after long-term use.

The present application relates to the technical field of optical engineering and digital twin cross, and specifically provides a practical optical system and simulation model parameter consistency control method, comprising: establishing a simulation model of a practical optical system, defining parameters of each element in the simulation model as variables, measuring parameter values of each element of the practical optical system and assigning values to the simulation model, obtaining simulation performance values of the simulation model and performance values of the practical optical system under the same conditions, and comparing to generate a performance consistency error report, determining potential error elements according to the performance consistency error report, and correcting errors through a virtual compensator and a phase plate to obtain a digital twin of the practical optical system. The present application systematically realizes correction of the simulation model and solves the problem of disconnection between the practical optical system and the simulation model.

The invention discloses an image fusion method based on a mixed multi-order diffraction lens, a medium and a program product, and relates to the technical field of image processing and optical engineering. First diffraction imaging data output by a mixed multi-order diffraction lens are obtained and input into a restoration network to obtain restored second diffraction imaging data, so that the defects of diffraction imaging are overcome. Furthermore, the image fusion network fully considers the scene of inherent degradation characteristics of the diffraction image during model training, and constructs a training sample more conforming to diffraction imaging characteristics, so that a stable and high-quality fusion result can be obtained by inputting the second diffraction imaging data into the fusion network. According to the two-stage fusion strategy provided by the invention, while the advantage of HMODL compact imaging is reserved, the detail representation and information integrity of dual-band imaging can be remarkably improved, and meanwhile, the robustness and application value of the system under the actual diffraction imaging condition are enhanced.

The application provides an assembling and adjusting method and assembling and adjusting tool of an off-axis optical system, and belongs to the technical field of optical engineering. The method is characterized in that: a computer holographic element is designed and processed, the surface type position of a primary mirror is detected and determined by using the computer holographic element, the frame position of the off-axis optical system is determined by using a laser tracker and a standard sphere, and a secondary mirror is adjusted by designing and using an off-axis mirror adjusting tool, so that the full field wave front of the off-axis optical system meets the requirements.

The invention relates to the technical field of optical engineering and digital twinborn crossing, and particularly provides a parameter consistency control method for an actual optical system and a simulation model, which comprises the following steps of: establishing the simulation model of the actual optical system, and defining parameters of each element in the simulation model as variables, parameter values of all elements of the actual optical system are measured, assignment is conducted on the simulation model, simulation performance values of the simulation model and performance values of the actual optical system are obtained under the same condition, a performance consistency error report is generated through comparison, elements with potential errors are determined according to the performance consistency error report, and the simulation performance values of the simulation model and the performance values of the actual optical system are obtained. Error correction is carried out through the virtual compensator and the phase plate, and digital twinning of an actual optical system is obtained. According to the invention, the correction of the simulation model is systematically realized, and the problem that actual optics and the simulation model are disjointed is solved.

The invention relates to an imaging lens for digital light processing 3D printing system. The lens comprises 8 lenses, which are in turn passed after reflection from a digital micromirror array: meniscus 1, convex lens 2, biconvex lens 3, concave lens 4, biconvex lens 5, convex lens 6, biconvex lens 8. The invention uses optical engineering principles to design a customized imaging lens for DLP 3D printing system, which has the advantages of structural symmetry, clear imaging and high degree of freedom. In addition to improving the imaging quality of the DLP 3D printing system, the structural printing precision can be further improved, the application range is wide, and the customizability of related products is improved.

This invention discloses a two-stage suspended, two-dimensional, precision-adjustable, large-mass optical load gravity unloading device, belonging to the fields of optical engineering and precision machinery technology. It includes a fixed base, on which a fixed frame is mounted. A two-dimensional precision rotation mechanism is mounted on the fixed frame, each comprising two-dimensional rotating shafts symmetrically arranged within the fixed frame. A large-mass optical load is fixedly mounted between the two rotating shafts. A two-stage torsion balance mechanism is mounted on the fixed frame. This invention, employing the aforementioned two-stage suspended, two-dimensional, precision-adjustable, large-mass optical load gravity unloading device, can maintain the gravity unloading state while completely unaffecting the precision directional adjustment performance of the large-mass optical load in the two-dimensional direction.

The application provides a kind of extracellular vesicle quantitative detection method based on self-interference spectrum reconstruction, it is related to the intersection field of biomedical detection and optical engineering.The method comprises: adding clinical sample into digital microfluidic chip, and separating sample droplet from droplet with functional modification magnetic bead by electrode;After mixing two droplets, add vesicle binding solution and mix, then incubate;Through magnetic control fixed magnetic bead, remove solution, then add deionized water to clean magnetic bead;After removing magnetic bead cleaning solution, add vesicle eluent and incubate with magnetic bead;Separate out the droplet containing extracellular vesicle;Transfer the droplet containing extracellular vesicle to the upper of gold-coated glass, remove droplet after incubation;Use deionized water to clean hybridized gold-coated glass;Use self-interference spectrum imaging system to detect vesicle quantity and its particle size distribution.The application can realize extracellular vesicle quantitative counting, particle size measurement and surface protein marker detection simultaneously, and improve single vesicle quantitative imaging precision and detection efficiency.