The invention discloses an experiment practical training device of a central air-conditioning system, which comprises a cooling tower, a control platform, a part mounting frame, a high lever water tank, a simulation air-conditioning area, a simulation boiler and a system frame, wherein the cooling tower, the part mounting frame, the high lever water tank and the simulation boiler are arranged on the system frame. Using the experiment practical training device, various works which are experiment practical training teaching of the central air-conditioning system, engineering training, the application of sensor detection technique, programmable control technique and the development of configuration technical program and the like can be done, and the experiment practical training device has a large practical value.