Disclosed are oral care compositions comprising selected surface-active
organophosphate compounds and methods of use to provide protection of teeth from
erosion caused by the action of chemicals, such as harsh abrasives and acids. The surface-active
organophosphate compounds are substantive to teeth, the
phosphate groups binding the
calcium in teeth and thus preventing loss of
calcium from
dissolution when contacted with acids. The
organophosphate compound may also deposit a protective
surface coating that prevents contact of teeth with erosive challenges. Selected organophosphate compounds contain one or more
phosphate groups and are combined in the oral care composition with one or more of a
fluoride ion agent, an
antimicrobial agent preferably selected from
quaternary ammonium compounds and polyvalent
metal salts, an anticalculus agent and additional surfactant, to provide benefits including superior anti-
erosion, anticaries, antiplaque and anti-
staining as demonstrated by enhanced
fluoride uptake, remineralization, resistance to acid
demineralization and
antimicrobial activities, resulting in improved overall tooth health,
structural integrity and appearance.