17434results about "Surgery" patented technology

A stop for use with an electric drill bit, the stop having at least one threaded sleeve for positioning the stop relative to a surface into which the drill bit will extend. The stop may have both an inner and an outer sleeve. The sleeves are mounted coaxially, one inside the other about the drill bit. One of the sleeves, preferably the inner sleeve, provides coarse adjustment of the position of the shoulder relative to the tip of the bit, while the other, preferably the outer sleeve, provides fine adjustment of the position of the shoulder relative to the top of the bit.

The invention discloses a thrombus excision system. An embolus is extracted through a mechanical embolus extraction device, a blood vessel is dredged, and revascularization of the blood vessel is achieved. A saccule guide catheter is put at the near end of the embolus part when the embolus is extracted, blood flow is temporarily blocked, and thus a fine crushed embolus generated in the embolus extraction process is prevented from being flushed to the far end of the blood vessel; meanwhile, for a relatively large embolus, a part of thrombus can also be sucked by virtue of the saccule guide catheter, and then the residual thrombus can be extracted by virtue of a thrombus exsector. The thrombus exsector, the saccule guide catheter and a delivery microcatheter are arranged on the thrombus excision system disclosed by the invention, wherein the thrombus exsector is used as a main component, an excision spring is arranged, and the release state of the excision spring is a conical spiral state. Compared with the prior art, the thrombus excision system has the advantages that the thrombus exsector is very soft, the minimal through size is 0.014' (0.36mm), the thrombus exsector can easily enter a cerebral vessel, a near-end protection technology is adopted in the operation process, and thrombus suction is combined with mechanical embolus extraction, so that the success rate of the operation is improved, and the complications are reduced.

Glucose and ketones may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using an analyte sensor capable of detecting both analytes. Certain analyte sensors capable of dual detection may comprise a first working electrode and a second working electrode, a ketones-responsive active area disposed upon a surface of the first working electrode, a glucose-responsive active area comprising a glucose-responsive enzyme disposed upon a surface of the second working electrode, a membrane having a first portion overcoating the ketones-responsive active area and a second portion overcoating the glucose-responsive active area, in which the first portion and the second portion have different compositions. The ketones-responsive active area comprises an enzyme system comprising at least two enzymes that are capable of acting in concert to facilitate detection of ketones.

Various embodiments of the systems, methods and devices are provided comprising angioplasty to break up calcification or other tissue in occlusive areas within a blood vessel. The various embodiments disclosed comprise pressure pulse periods designed to break up calcified occlusive material through a cyclically stretching of the vessel walls without damaging the vessel wall tissue.

A heart valve repair apparatus is disclosed. The apparatus has a radially expandable ring having a first ring component connectable to a second ring component by a pair of securing members, a tube structure, and a net structure extending distally from the ring to the tube structure. The net structure comprises a plurality of cells, each of which defines a hollow space which may comprise a quadrilateral shape or a pentagon shape. The net structure also comprises a plurality of positioning cords connecting the plurality of cells to the tube structure. In some embodiments, one or more tabs are arranged to project outwardly from an inner circumferential surface of the ring, aligned and dimensioned to allow passage of a tether therethrough.

Disclosed is a negative pressure suction sheath, comprising a sheath tube (1), a negative pressure connector (2), and a dilator (3). The negative pressure connector (2) comprises a main channel cavity (201) and a negative pressure suction channel cavity (202) located on one side of the main channel cavity (201). A proximal end of the sheath tube (1) is connected to a distal end of the main channel cavity (201). The dilator (3) is inserted from a proximal end of the main channel cavity (201) and extends out of a distal end of the sheath tube (1) and is detachably connected to the main channel cavity (201). A side channel port (205) is formed on one side of the main channel cavity (201), and the negative pressure suction channel cavity (202) is in communication with the side channel port (205). A cavity wall of the main channel cavity (201) is further provided with a pressure regulating port (203). The pressure regulating port (203) is arranged corresponding to the side channel port (205) or is located at one end of the side channel port (205) distal to the sheath tube (1), and the magnitude of the negative pressure in the sheath tube (1) can be adjusted by adjusting the opening size of the pressure regulating port (203).

Milling device for prosthetic surgery comprising a milling tool rotating about a milling axis, and a handling body. The handling body is provided with a drive rotating rod which develops along a longitudinal axis of linear rotation and is connected to the milling tool in order to make the milling tool rotate about the milling axis.

The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and / or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and / or dynamically identify one or more features, such as plaque and vessels, and / or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, perform computational fluid dynamics analysis, facilitate assessment of risk of heart disease and coronary artery disease, enhance drug development, determine a CAD risk factor goal, provide atherosclerosis and vascular morphology characterization, and determine indication of myocardial risk, and / or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and / or quantified parameters.

The invention relates to a painless gastrointestinal endoscope self-adaptive drug delivery method and system based on multi-source physiological signal fusion, and belongs to the technical field of medical artificial intelligence and automatic control. An artificial intelligence model is utilized to deeply extract features and quantitatively evaluate the sedation-analgesia level of a patient, a pharmacokinetics-pharmacodynamics model constructed by a big data platform is utilized to dynamically predict the drug effect according to the individual features and real-time state of the patient, and the anesthetic infusion rate is automatically and accurately adjusted through a closed-loop control algorithm, so that the patient can be accurately infused. Personalization and self-adaption of drug delivery are achieved, an independent safety monitoring mechanism is set, and real-time intervention is conducted on risk events such as respiratory depression. The problems that traditional anesthesia depends on artificial experience, single parameter monitoring is not comprehensive and individualized dynamic adjustment is lacked can be effectively solved, and the safety, comfort and medical efficiency of painless gastrointestinal endoscopy are remarkably improved.

The application belongs to the technical field of zinc alloy, and particularly relates to an anti-aging high-strength and high-toughness degradable zinc alloy bar, a preparation method and application, which comprises the following components by weight percentage: Cu 1.5-2.0%, Mg 0.01-0.05%, and the balance of Zn; the preparation method of the anti-aging high-strength and high-toughness degradable zinc alloy bar is that zinc alloy ingots are sequentially subjected to homogenization treatment and multi-pass rotary forging treatment to obtain the anti-aging high-strength and high-toughness degradable zinc alloy bar, and the number of passes is more than 7; the application has good strength, toughness and anti-aging capacity.

The invention belongs to the field of biological materials, and particularly relates to recombinant V-type humanized collagen and application thereof. The invention provides a recombinant V-type humanized collagen, the amino acid sequence of the recombinant V-type humanized collagen comprises (repetitive unit) n, and the repetitive unit comprises a sequence as shown in SEQ ID NO.1; each repeating unit is directly linked and the number n of repeating units is 10. The recombinant V-type humanized collagen can comprehensively resist skin aging.

The invention relates to a trauma first-aid intervention time optimization management system and method based on multi-modal data fusion, and is suitable for high-timeliness trauma treatment scenes. The method comprises the following steps: S1, collecting and standardizing multi-source heterogeneous data from physiological monitoring, an image system, text recording and the like; s2, extracting each modal feature, and generating an intermediate semantic representation; s3, constructing a multi-mode cooperative control mechanism, and dynamically allocating a dominant mode and an auxiliary mode according to a TIPT task node state to realize semantic information intercommunication; s4, adjusting the fusion weight based on the time sensitivity score, and realizing adaptive regulation and control of modal fusion; s5, the task path scheduling module automatically starts a standby strategy when the key mode is missing or delayed, and task propulsion continuity is guaranteed; and S6, outputting diagnosis and treatment suggestions and performing task closed-loop feedback. The method can effectively improve the data fusion efficiency and decision reliability in the time-sensitive medical task, and has good clinical practicability and popularization prospects.

The invention relates to the technical field of chronic kidney disease screening, and discloses an intelligent chronic kidney disease early screening instrument which comprises a physiological parameter detection module configured to synchronously collect multi-dimensional bio-electricity signals, optical characteristic parameters and body fluid biochemical parameters of a subject and output original signals; the multi-modal data processing module is in communication connection with the physiological parameter detection module and is configured to receive original signals, perform time domain and frequency domain conjoint analysis and construct a parameter incidence matrix; the wireless communication module is configured to realize encrypted interaction between the screening data and the cloud server and block chain evidence storage; and the man-machine interaction module is configured to display the risk level map in real time. According to the method, holographic dynamic correlation modeling of kidney function related micro-electrophysiological fluctuation and optical metabolism characteristics is realized, and a specific cross-modal pathological correlation mode of early renal injury can be effectively identified based on a time-frequency domain combined characteristic extraction and dynamic coupling algorithm.

The invention relates to the technical field of coating surface preparation, in particular to an anticoagulant coating based on novel tick-derived anticoagulant protein Qinghaenin and a preparation method of the anticoagulant coating. The functional layer of the anticoagulant coating comprises the following components: anticoagulant protein Qinghaenin or a functional peptide fragment Qinghaenin 167-192 of the anticoagulant protein Qinghaenin, wherein the amino acid sequence of the functional peptide fragment is as shown in SEQ ID NO. 2. The preparation method of the anticoagulant coating comprises the following steps: by using a polydopamine coating as a substrate layer, covalently grafting through an amido bond, immobilizing anticoagulant protein Qinghaenin capable of inhibiting FXII factor activation or a functional peptide fragment Qinghaenin 167-192 thereof on the surface of a medical polymer material, and successfully constructing a novel anticoagulant coating. Compared with an unmodified medical polymer material, the modified coating can significantly enhance the hydrophilic performance of the material and inhibit platelet adhesion and activation, finally effectively prolongs the in-vitro blood coagulation time, and shows excellent anticoagulation performance.

The invention discloses an oral cavity data monitoring and early warning method and system based on deep learning, and the method comprises the steps: solving a problem that the focus recognition is inaccurate because the image collection process of an oral cavity endoscope of a patient is affected by various environment and equipment parameters; according to the method, synchronous binding of collected images and equipment parameters and intelligent image preprocessing are proposed, historical time sequence images and variation trend features are combined, lesion space and time features are extracted through combination of a lightweight convolutional neural network and a long-short term memory network, feature weighted reasoning is realized by using a context awareness attention fusion network, and the focus space and time features are extracted. According to the method, the model parameters and the risk threshold value can be dynamically adjusted, the focus recognition accuracy and the early warning individuation are improved, and clinical grading treatment and intelligent health management are effectively assisted.

The invention belongs to the technical field of medical equipment. The endoscopic surgery operation quality real-time quantitative evaluation system comprises an endoscopic camera probe used for collecting endoscopic images and an endoscopic handle used for operation. The displacement sensor is integrated on the endoscope camera probe and is used for detecting the endoscope entering speed; the pressure sensor is integrated on the gas injection pipeline and is used for detecting the intracavity pressure; the force sensor is integrated on the endoscope handle and is used for detecting the tissue traction deformation; the optical coherence layer scanning probe is integrated on the endoscope camera probe and used for detecting the thickness of the submucous membrane, and the processing terminal is used for conducting real-time quantitative evaluation on the endoscopic surgery operation quality according to the endoscope entering speed, the intracavity pressure, the thickness of the submucous membrane, the tissue traction deformation image, the included angle between an instrument and a focus normal and the complication response time. According to the invention, full-process datamation real-time accurate evaluation of operation skills and operation safety of operators is realized.

The invention discloses an insertion tube and a manufacturing method thereof, an insertion part and an endoscope, and relates to the technical field of medical instruments, the insertion tube comprises an insertion body and an elastic tube, a first reinforcing layer and a second reinforcing layer are arranged in the insertion body, the second reinforcing layer is arranged outside the first reinforcing layer in a surrounding mode, and the first reinforcing layer is provided with a concave part. The first reinforcing layer and the second reinforcing layer can form double limiting and wrapping supporting on the elastic pipe, the concave shape of the concave part of the first reinforcing layer is utilized to be attached to the outer wall outline of the elastic pipe, and the outer side of the second reinforcing layer is matched for enclosing and restraining, so that the installation stability of the elastic pipe in the first channel can be greatly improved; bending moment generated by self-gravity, external force and the like of the elastic tube is effectively counteracted, the elastic tube is prevented from being bent under the action of self-gravity, external force and the like, the whole insertion tube is prevented from deforming along with bending of the elastic tube, and the form stability of the insertion tube in the cavity in the propelling process is guaranteed. And the straightness of a traction rope transmission path and the accurate conduction of a control instruction are ensured.

Image acquisition device comprising: - a support (12); - a dental retractor (14) fixed to the support and defining a retractor opening (24); and - means for fixing an image acquisition device to the support in a position in which the acquisition device is oriented to receive an image of the retractor opening.

The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and / or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and / or dynamically identify one or more features, such as plaque and vessels, and / or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and / or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and / or quantified parameters.

A mask-based diagnostic apparatus is provided for detecting a biomarker contained in exhaled breath of a test subject. An exhaled breath condensate (EBC) collector converts breath vapor received from the lungs and airways of the test subject into a fluid biosample. The EBC collector including a thermal mass, a condensate-forming surface and a fluid conductor disposed on the condensate-forming surface. A fluid transfer system receives the fluid biosample from the EBC collector. A biomarker testing unit receives the fluid biosample from the fluid transfer system and tests the fluid biosample for a target biomarker. A testing system support is provided for supporting the EBC collector, the fluid transfer system and the biomarker testing unit. The testing system support is configured and dimensioned to fit inside a face mask. A face mask is provided forming an exhaled breath vapor containment volume to hold the exhaled breath vapor in proximity to the EBC collector to enable the condensate-forming surface cooled by the thermal mass to coalesce the exhaled breath vapor into the fluid biosample.

A method of preparing and / or delivering an osteochondral plug may include, positioning a tissue graft on a cutting guide, wherein the tissue graft may have been removed from a larger body of tissue to define a shaped surface. The tissue graft may include a top surface having a cartilage surface. The method may further include advancing a first cutter along a cutting direction toward the tissue graft to cut the tissue graft to form the osteochondral plug having an external wall parallel to the cutting direction and transverse to the top surface. Positioning the tissue graft on the cutting guide may include placing the shaped surface on a registration surface of the cutting guide. The registration surface may have a reference shape that corresponds to a shape of at least part of the shaped surface.

The present invention relates generally to improved systems and methods for removing undesirable material residing in vessels. More specifically, the present invention relates to systems and methods for using at least one cannula to remove substantially en bloc, from a site of obstruction or interest, undesirable material without fragmentation and without excessive fluid loss.

Sheets of material used in medical devices and filters are disclosed. The sheets may include a fibrous mat including a plurality of microfibers. The microfibers may include a polymer matrix and a plurality of additive particles. The additive particles may include carbon material particles, therapeutic micro particles, and any combination thereof. Medical devices and filters that use the sheets are disclosed. Methods of producing the sheets are also disclosed.

The utility model discloses a macromolecular anti-unwinding spring ring, which relates to the technical field of spring rings and comprises a connecting piece, a spring ring and a macromolecular anti-unwinding wire, a releasing groove is formed in the connecting piece and used for being connected with the pushing rod, and a connecting block is arranged at the end of the connecting piece; one end of the spring ring is connected with the connecting block; one end of the macromolecular anti-unwinding wire is connected with the connecting block, and the other end of the macromolecular anti-unwinding wire is connected with the round head end. According to the macromolecule anti-unwinding spring ring, the two ends of the spring ring are connected with the connecting piece and the round head end, the macromolecule anti-unwinding wire is arranged in the spring ring, and the two ends of the macromolecule anti-unwinding wire are connected with the connecting block on the connecting piece and the round head end respectively, so that it is guaranteed that the length of the spring ring is fixed; the embolism spring is prevented from being straightened under the action of external force in the implanting and using process, the function of the spring structure is kept, the embolism efficiency can be remarkably improved, safety and reliability are achieved, and meanwhile the safety of an interventional operation is improved.

The invention discloses a sealing structure, a negative pressure suction sheath and an endoscope assembly, and belongs to the technical field of medical instruments. The sealing structure is used for the negative pressure suction sheath and comprises a first cover body detachably connected with the near end of a sheath base of the negative pressure suction sheath, a first through hole is formed in the middle of the first cover body, and a first air hole is formed in the radial outer side of the first through hole; the second cover body is arranged on the outer side of the first cover body in a sleeving mode and detachably connected with a sheath base of the negative pressure suction sheath, a second through hole is formed in the middle of the second cover body, and a second air hole is formed in the radial outer side of the second through hole; the second cover body and the first cover body are in sliding fit, and the overlapping opening degree of the first air hole and the second air hole is adjusted through relative sliding; the second cover body axially limits the first cover body and provides support when the endoscope is inserted, so that the first cover body is prevented from collapsing. The sealing structure is used for the negative-pressure suction sheath, the branch switch is prevented from additionally occupying the operation space, and the operation safety is improved.

A method of extracting a thrombus from a thrombus site in a cerebral artery of a patient by advancing a first catheter into an internal carotid artery of the patient; advancing a funnel catheter within the first catheter; moving the funnel catheter and the first catheter with respect to each other to place the funnel outside of the first catheter; expanding the funnel into contact with an inner wall of the internal carotid artery at or proximal to a distal end of a carotid siphon, thereby reducing blood flow past the funnel; advancing a clot-mobilizer distally through the first catheter toward the thrombus and beyond the carotid siphon; engaging thrombus material from the thrombus with the clot-mobilizer; moving the clot-mobilizer and thrombus material proximally at least partially into the funnel; applying suction to aspirate thrombus material; and moving the funnel, the clot-mobilizer and the thrombus material proximally within the vasculature.

The utility model provides a guiding device and dilator for improving pressure measurement accuracy, the guiding device comprises a pressure measurement sheath, the pressure measurement sheath comprises a handle and a sheath tube, the size and shape of the sheath tube are suitable for entering a target area in a body through a body lumen, the sheath tube longitudinally extends from a near end to a far end, the sheath tube defines a first lumen suitable for entering of an external instrument, and the first lumen is communicated with the handle. A pressure measuring tube cavity longitudinally extending from the near end to the far end is formed in the tube wall of the sheath tube, a pressure measuring opening used for sensing the pressure of liquid in the body is formed in the far side of the pressure measuring tube cavity, and the dilator is arranged in the first tube cavity in a supporting and penetrating mode so that the pressure measuring sheath can enter the body conveniently. And the dilator is provided with a blocking part for limiting foreign matters from entering the pressure measuring tube cavity through the pressure measuring port.

The invention relates to a deep vein thrombectomy support device which has the advantage of being convenient to clean. The inner tube assembly comprises an inner tube, a conical head assembly and a limiting key, the inner tube and the handle assembly are matched in the mode that the inner tube can slide axially but cannot rotate relative to the circumferential direction, the conical head assembly is arranged at the far end of the inner tube, the limiting key is movably installed on the handle assembly, and the limiting key selectively acts on the inner tube; the middle tube assembly comprises a middle tube and a support fixing assembly, the near end of the middle tube is connected to the handle assembly, and the far end of the middle tube is connected with the support fixing assembly; the outer pipe assembly comprises an outer pipe which can be axially and movably arranged on the middle pipe in a sleeving manner; the thrombectomy stent assembly comprises a self-expansion stent and a woven mesh, the near end of the self-expansion stent is connected with the stent fixing assembly, the near end of the woven mesh is connected to the far end of the self-expansion stent, and the far end of the woven mesh is connected to the conical head assembly.

The invention relates to the technical field of medical interventions, and discloses a difficult-to-layer composite woven balloon and a preparation method thereof, the difficult-to-layer composite woven balloon comprises an inner balloon and a fiber line structure woven on the outer surface of the inner balloon; the fiber thread structure is divided into warp threads and weft threads, the fiber threads extending in the diameter direction of the balloon are the warp threads, and the fiber threads extending in the axial direction of the balloon are the weft threads; the inner balloon is sequentially subjected to surface treatment, primer treatment, fiber weaving, surface treatment, surface sizing and surface curing treatment. The preparation process does not need complex special equipment, the material requirement is reasonable, the repeatability is high, the production difficulty and cost are reduced, convenience is provided for large-scale application of the material, and the material has extremely high practical value and popularization potential in medical scenes such as vascular stenosis dilation and calculus dilation pathway establishment.

The invention discloses an ultra-wide-spectrum endoscopic imaging device capable of being used for short-wave infrared fluorescence imaging, which is used for in-vivo minimally invasive imaging and comprises an illumination module, a wide-spectrum image transmission module, an imaging module and an image processing module. The illumination module consists of a light source and a light guide optical fiber, and is used for generating illumination light from ultraviolet to short wave infrared band and transmitting the illumination light to the wide-spectrum image transmission module; the wide-spectrum image transmission module consists of a few-interface optical imaging channel and a light guide illumination channel, and is used for illuminating an imaging target, exciting target fluorescence and collecting image signals from ultraviolet to short-wave infrared bands; the imaging module is composed of an optical filter and an imaging camera, and the imaging camera can be a wide spectral response image sensor or can be formed by combining cameras working in different wavebands and is used for converting optical images in different wavebands into image data; and the image processing module is used for registering and fusing image data of different wavebands in real time and displaying the image data.