145 results about "Bone implant" patented technology

The invention discloses a method and a system for testing corrosion fatigue of a bone implantation device under a pathological condition, and relates to the technical field of orthopedic medical device evaluation, and the method comprises the following steps: constructing a dynamic load spectrum database covering physiological and pathological states; in-vitro reproduction of a dynamic mechanical environment borne by the bone implantation instrument in physiological and pathological states is completed through a multi-axis servo system; and acquiring service state data of the bone implantation instrument, and analyzing the service state data of the bone implantation instrument to obtain coupling experiment data. According to the invention, the defects of single load mode and environment simulation distortion in the traditional test method are overcome, high-fidelity simulation and comprehensive monitoring of the corrosion fatigue behavior of the bone implantation device under the pathological condition are realized, the consistency of the in-vitro test result and the in-vivo actual service performance is improved, and the application prospect is wide. And a scientific and unified evaluation basis is provided for material screening, structure optimization and service life evaluation of different types of bone implantation instruments.

The invention of the gradient porous structured sacral prosthesis and the manufacturing process aims to create an alternative replacement for bone loss in patients who require bone replacement. The gradient porous structured sacral prosthesis consists of an artificial bone fragment, a metal rod, and a set of screws for fixing the fragments. The manufacturing process consists of seven steps: Identifying the position and boundaries of the bone, First-step topology optimization, Second-step topology optimization, Defining the structural pattern and unit cell size, Designing the artificial bone implant, Mechanical performance testing of the implant, and Fabrication of the sacral implant. The devices and processes according to the present invention are clearly sequenced and characterized. Modification or change in the manufacturing sequence or use may reduce the capabilities of the present invention or make it unusable for the purposes of the present invention.

The invention discloses a bark crack bionic lattice structure design method based on a three-period minimal curved surface, a bark crack bionic lattice structure and a bone implantation stent. The bark crack bionic lattice structure design method comprises the following steps: S1, constructing a parent lattice structure by adopting a three-period minimal curved surface function; s2, crack characteristics are constructed in the matrix lattice structure through a bidirectional offset contour surface method, a bark crack bionic lattice structure is formed, and the crack size and the relative density are controlled through offset parameters; s3, the relative density of the bark crack bionic lattice structure is calculated through triple integration, and the volume fraction of the generated model is controlled; and S4, crystal orientation design and rotation angle design are conducted on the bark crack bionic lattice structure, so that the elastic modulus and mass transfer performance of the bark crack bionic lattice structure are regulated and controlled.

The invention discloses a bionic Voronoi-nickel titanium-hydrogel heterostructure implant and a preparation method thereof, and relates to the technical field of bone implantation, the construction of a Voronoi porous structure and the preparation of a bionic Voronoi-nickel titanium skeleton are completed through an innovative design method by referring to the structural concept of human bone trabecula, and then the bionic Voronoi-nickel titanium skeleton is used as a substrate to prepare the bionic Voronoi-nickel titanium hydrogel heterostructure implant. And preparing the bionic Voronoi-nickel titanium-hydrogel heterostructure implant by adopting a drying gel forming method. The implant integrates the mechanical advantages of high strength and low modulus of the nickel-titanium alloy and the structural characteristics of high connectivity and high specific surface area of the bionic Voronoi porous structure, the defect that hydrogel is weak in bearing is effectively overcome, meanwhile, the hydrogel has the buffering and energy absorbing effects, multifunctional time sequence delivery and release of antibiosis, anti-inflammation and bone regeneration promotion can be achieved, and the requirements of all stages of bone repair are met.

In some embodiments, a bone implant for percutaneous use is provided. The bone implant comprises a head, a body adjacent to the head and a tip opposite the head. At least the head, body or tip is configured to contact bone. An expandable member contacts at least one of the head, tip or body and is movable from an unexpanded configuration to an expanded configuration when deployed at a bone implant site. In some embodiments, a system for percutaneous bone harvesting is provided.

Disclosed herein are compositions and methods to create bone implants that are biocompatible and custom designed to implant in a bone lesion. The implant comprises a unique scaffolding customized to the bone lesion and combined with one or more specialized proresolving mediators (SPM). According to certain embodiments, the scaffolding matrix comprises an alloplastic material developed into a matrix and including one or more SPM including synthetic SPM and natural SPM wherein the SPM is released over time.

Provided is a total talar replacement prosthesis that has a metallic body shell and a metallic or biologic core, where the metallic body shell includes one or both of a removable calcaneus attachment and a removable navicular attachment. The attachments, when removed, exposes a respective calcaneus-facing surface or a navicular-facing surface that can enhance fusion to the respective bones, calcaneus and / or navicular.

This invention relates to the field of biomedical materials technology, specifically to a method and application for the fabrication of heterogeneous metal bone implants. The fabrication method includes the following steps: S1: obtaining a physical model of the bone implant; S2: generating an L-PBF printing file based on the physical model of the bone implant to obtain a porous model of the bone implant; S3: based on the L-PBF printing file, using multi-material laser powder bed melting technology, performing integrated multi-material L-PBF printing with two or more different metal powders having large differences in melting and boiling points to obtain a porous heterogeneous bone implant blank; finally, post-processing the porous heterogeneous bone implant blank to obtain a heterogeneous metal bone implant. The fabrication method of this invention solves the core technical problem of weak interfacial bonding and easy failure in multi-material implants, and also addresses the problem of large differences in melting and boiling points between two metal materials.

An expandable bone implant for human orthopaedic surgery for restoring the volume and / or geometry of a bone, to an orthopaedic system and to a method for manufacturing the implant which includes a hollow body formed by a sheet made of a biocompatible metal alloy, closed on itself in a sealed manner, between proximal and distal ends, having, in the folded configuration, a plurality of pairs of folds, each of the pairs having an antiform fold, referred to as convex, and possible persistence of a synform fold, referred to as concave, the folds lying on top of each other in the folded configuration so that the surfaces present between each of the convex and concave folds are rolled around the longitudinal axis, the sheet being plastically deformable to allow expansion of the implant from the folded configuration to the deployed configuration, when a fluid is injected into the implant.

This invention discloses a method for depositing hydroxyapatite in a three-dimensional porous sample, comprising: S1, pretreatment of the three-dimensional porous sample; S2, placing the three-dimensional porous sample in an O... 2 In a plasma spraying apparatus; S3, prepare SBF1, immerse the sample treated in step S2 into SBF1, seal the container tightly, and place it in an incubator. After immersion in SBF1, remove the sample, wash and dry it. SBF1 contains the following components: CaCl2, MgCl2·6H2O, NaHCO3, K2HPO4·3H2O, Na2SO4, KCl, and NaCl; S4, prepare SBF2, immerse the sample treated in step S3 into SBF2, seal the container tightly, and place it in an incubator at 37°C. SBF2 contains the following components: NaCl, CaCl2, and K2HPO4·3H2O; S5, remove the sample, wash and dry it to obtain a three-dimensional porous sample with deposited hydroxyapatite. The method provided by this invention uniformly deposits HA in the porous three-dimensional void surface, and the composite interface can accelerate early bone healing, increase the integration of the bone implant surface with the bone, and promote the early stability of the implant.

The present application relates to a kind of self-setting composite bone implants based on gallic acid complex salt and preparation method thereof, belong to bone repair material field.The present application is specifically related to a kind of self-setting composite bone implants, it is characterized in that, component A, component B and component C, the component A is gallic acid and the complex salt of at least two metal elements, wherein the at least two metal elements are the metal element of promoting bone tissue regeneration or the trace metal element required by human body, and the at least two metal elements include calcium, the component B is the complex of calcium / strontium chondroitin sulfate and calcium sulfate, and the component C is magnesium calcium hydrogen phosphate complex.The self-setting composite bone implant of the present application has the characteristics of antibacterial, anti-inflammatory, promoting osteogenesis, instant shaping and all degradation, can meet the clinical needs of bone tumor, bone injury and the like, has wide application prospect in various bone repair, reconstruction and replacement.

The application discloses a multifunctional antibacterial coating bone implant device based on a selective vacuum perfusion process and a preparation method thereof. The method comprises the following steps: 1) pretreating a titanium alloy base; 2) performing anodic oxidation treatment on the pretreated titanium alloy base to construct a nanotube structure on the surface of the titanium alloy base; 3) selectively coating the treated titanium alloy base with a hydrogel adhesive, then immersing the titanium alloy base in a povidone iodine mixed solution to perform vacuum perfusion, and performing post-treatment, then again performing selective coating, immersing the titanium alloy base in a solution containing a bone growth promoting factor to perform vacuum perfusion, and performing post-treatment, then again performing selective coating, immersing the titanium alloy base in a solution containing a blood vessel growth promoting factor to perform vacuum perfusion, and performing post-treatment; and 4) encapsulating the obtained sample surface with an in-situ self-polymerized polydopamine layer, washing and freeze-drying. The bone implant device has antibacterial, bone growth promoting and blood vessel growth promoting functions, and can greatly improve the curative effect on bone fracture symptoms accompanied by infection.

The described system designed to promote the biological attachment of fibrous connective tissue to a bone implant features a bone implant with a scaffold defining a porous attachment surface, a suction port, and a manifold that distributes a negative pressure gradient across the attachment surface. The system also includes an extracorporeal vacuum pump and a percutaneous suction hose connecting the suction port of the implant to the vacuum pump. The implant is placed in the patient's body with connective tissue applied over the attachment surface, and the suction hose is attached and connected to the vacuum pump. The vacuum pump, operating outside the body, creates a negative pressure gradient over an extended period, promoting the growth of slow growing Sharpey's fibres for superior biological integration. A highly vascularised tissue graft, such as a pedicled muscle flap, may be applied adjacent to the avascular tendon to enhance endogenous growth factor migration.

A modular bone implant for affixation to a bone having a bone end surface and a bone side surface oriented at an angle with respect to each other. The implant comprises an anchor seat with an inner seat surface configured for abutting the bone end surface, and an elongate stem extending from the anchor seat with a proximal end portion, a distal end portion and a stem long axis. The proximal end portion comprises a planar surface obliquely angled relative to the stem long axis and configured for positioned placement under the bone side surface. At least one fixating element extends from the anchor seat adjacent the stem, having a fixator long axis parallel to the stem long axis and a length shorter than that of the stem. The implant may include a connecting portion configured to breach the bone side surface for attachment to a bone plate, which may be covered by a fixation plate.

The application discloses a kind of medical degradable WE43 / Zn interpenetrating phase composite material with body-centered cubic porous structure as framework and a preparation method thereof.The composite material is composed of WE43 magnesium alloy framework and zinc matrix;The WE43 framework is a body-centered cubic topology structure prepared by using laser selective melting technology, the porosity is 80%, and the topology structure with different strut thicknesses of 0.6mm, 0.8mm and 1.0mm is densified at 350 DEG C low temperature quickly.The composite material utilizes the strong "space constraint effect" generated by the small strut network, not only avoids the generation of continuous brittle intermetallic compounds at high temperature, but also realizes excellent metallurgical bonding and stress transfer.The ultimate compressive strength of the material can be up to 276MPa, and the degradation is stable, the biocompatibility is good, the problems of insufficient strength of pure zinc and too fast degradation of magnesium alloy are effectively solved, and the material has wide application prospect in the field of medical load-bearing bone implants.

The present invention relates to a system and a method for planning veterinary orthopedic surgery, for restoring volume and / or geometry of a bone, by expansion of at least one expandable bone implant (1) between a folded configuration and a deployed configuration, the implant comprising a body extending along a longitudinal axis (L) between a proximal end (11) connectable to an implantation instrument (A) for holding the implant and a distal end (12) intended to be inserted first into the bone, wherein the system comprises a plurality of expandable bone implants (1) and at least one implantation instrument (A) corresponding to each of the implants (1) and at least one planning support presenting the implants (1) and instrument (A), with reference to at least one standardized classification of the various types of fractures identified, in particular vertebral compression fractures, the planning support being capable of being implemented in the form of a human-machine interface.

A method for treating an artificial bone implant with blood, according to the method bone material is placed in a container configured to be filled with blood, wherein the container comprises an opening and a cover configured to cover the opening of the container and a fixed separator that separates a bottom part and an upper part. The separator is provided with holes so that when the container is filled with whole blood, the blood in the bottom part is in full contact with the blood in the upper part, and wherein the bone material is in the upper part, on top of the separator.

The invention discloses a shapeable bone repair material capable of being implanted in a positioning manner and a preparation method thereof. The interior of the bone repair material is a core layer made of a gelatin, gallic acid and hydroxyapatite particle composite material, and the exterior of the bone repair material is a porous spongy collagen wrapping layer; the density of the wrapping layer is 20-100mg / cm < 3 >; the density of the core layer is 100-800 mg / cm < 3 >; and the particle size of the hydroxyapatite particles is 0.1-2 mm. The collagen sponge on the outer layer of the material wraps the gelatin / hydroxyapatite composite material, so that the problems of loose structure, weak binding force and displacement and powder falling after implantation of bone meal or collagen bone meal composite materials are solved, stimulation and trauma of bone meal particles to surrounding tissues can be avoided, and the conditions of bone meal discharge, bone grafting part collapse and the like are avoided. And in the self tissue regeneration process, the collagen component is degraded and absorbed, and the hydroxyapatite is fused with the new bone, so that bone regeneration is realized, and the success rate of tooth implantation can be improved.

The application relates to the technical field of medical devices, and provides a minimally invasive nerve interface system, which comprises a plurality of micro bone implants implanted in target bone tissues, a wearable component and a nerve regulation system; the wearable component comprises a plurality of wearable units; the micro bone implants are implanted in micro channels constructed in the target bone tissues; the target bone tissues at least include skull and vertebrae; the wearable units are connected with the nerve regulation system and controlled by the nerve regulation system, the wearable units are wirelessly connected with the micro bone implants; the nerve regulation system is used for forwarding control instructions to the micro bone implants via the wearable units, controlling the micro bone implants to emit regulation signals, and / or receiving physiological signals collected by the micro bone implants and forwarded via the wearable units. The minimally invasive nerve interface system provided by the application can effectively reduce the influence of the bone tissues on signal collection and transmission, and avoid the invasiveness and risks of invasive operation.

The application provides an artificial lamina for spinal decompression surgery, which comprises an arc-shaped lamina, both sides of the arc-shaped lamina are provided with C-shaped rotating grooves arranged along the length direction, the cross section of each C-shaped rotating groove is greater than one-half of a circle, both sides of the arc-shaped lamina are rotationally connected with arc-shaped wing plates matched with the arc shape, one side of each arc-shaped wing plate is provided with a rotating connecting shaft matched with the corresponding C-shaped rotating groove, and the free side of each arc-shaped wing plate is provided with a connecting plug strip arranged in the arc direction of the arc-shaped lamina, and each connecting plug strip is a porous mesh structure. The application uses the embedding method of the porous mesh structure to fuse and fix with the vertebrae, so that the bone-implant combination is mechanically stable and irreversible.

A bone implant (10) for encapsulating bone material (12) is provided. The bone implant includes a cover (18), which may be a biodegradable mesh. The cover is configured to be wound to a certain diameter to at least partially encapsulate the bone material within the cover. In some embodiments, the cover includes a body portion (80) and a closure portion (82) adjacent to the body portion. The closure portion is configured to hold the cover in its wound configuration to a predetermined diameter to at least partially encapsulate the bone material. A kit and method of using the bone implant are also provided.

The application discloses a kind of biomimetic Voronoi-nickel titanium-hydrogel heterostructure implants and preparation method thereof, it is related to bone implant technical field, draw lessons from the structural concept of human bone trabecula, complete the preparation of Voronoi porous structure construction and biomimetic Voronoi-nickel titanium skeleton by innovative design method, again with the biomimetic Voronoi-nickel titanium skeleton as base, adopt drying gel method to prepare biomimetic Voronoi-nickel titanium-hydrogel heterostructure implant.The implant integrates the mechanical advantages of high strength, low modulus of nickel titanium alloy and the structural characteristics of high connectivity, high specific surface area of biomimetic Voronoi porous structure, effectively makes up the short board of hydrogel bearing weakness, while hydrogel has buffering energy absorption function, can realize the multi-functional time sequence release of antibacterial, anti-inflammatory, bone regeneration promotion, adapt to the needs of each stage of bone repair.

The invention relates to the technical field of bone implant testing, and discloses a bone implant anti-fatigue testing device which comprises a closed storage mechanism, a quasi-bending energy supply mechanism installed on the closed storage mechanism and a quasi-bending pressure bearing mechanism installed in the closed storage mechanism. The fatigue detection mechanism is mounted between the quasi-bending energy supply mechanism and the quasi-bending pressure-bearing mechanism; the bone implantation assembly is assembled on the fatigue detection mechanism; and the closed storage mechanism is used for providing permeation of the simulation medium for the fatigue detection mechanism. The two to-be-detected bone plates are respectively installed on the two corresponding assembly blocks, and a sealed storage environment is provided for the fatigue detection mechanism by means of the main shell and the auxiliary shell; the fatigue test can be carried out on the two bone plates by matching the quasi-bending function mechanism driven by the motor with the quasi-bending pressure-bearing mechanism so as to simulate the human body environment where the bone plate assembled on the bone joint is located for testing, and the authenticity of the anti-fatigue test of the selected bone plate can be enhanced.

The invention belongs to the field of biomedical metal materials, and discloses medical Ta-xTi alloy high-quality powder for additive manufacturing and a preparation method of the medical Ta-xTi alloy high-quality powder, and the powder is prepared from titanium powder, tantalum powder, a tantalum-doped titanium nitride coated amorphous carbon nano shell, yttrium-stabilized zirconium oxide coated mesoporous silicon dioxide nano particles and stearic acid according to a specific weight part ratio. The preparation process comprises the following steps: firstly, uniformly adsorbing nano tantalum powder and two modified compounds on the surface of micron-sized titanium powder through an electrostatic self-assembly technology to form core-shell structure composite powder; and then the composite powder is subjected to spheroidizing treatment through radio frequency plasma, and finally the high-quality alloy powder with the high sphericity degree and the good fluidity is obtained. According to the method, the problems of composition segregation and unmelted particles of high-melting-point tantalum and titanium in the selective laser melting forming process are solved, meanwhile, the material is endowed with lower elastic modulus and enhanced biological activity and antibacterial performance, and the method is particularly suitable for manufacturing high-performance customized bone implants.

Systems and related methods for preparing and treating damage in an ankle joint. The system may include one or more of a reamer, a surgical device, a tibial implant, a placement tool, and a talar implant. The reamer may prepare an intramedullary canal for implantation of an implant. The reamer may include a plurality of nested reamer elements that may be expanded into the intramedullary canal. The surgical device may include a housing containing the reamer and be configured to orient the reamer with the intramedullary canal. The tibial implant may include a plurality of stem components. The placement tool may be configured to combine the plurality of stem components. The talar implant may be configured to be implanted in a talus.

An implant, a system, and a manufacturing process for human orthopedic surgery for restoring the volume and / or geometry of a bone by expanding at least two faces of the implant, each including a flange, the bringing together of the distal (12) and proximal (11) ends causing the support arms to pivot, causing the flanges to move away from each other and, consequently, the implant to expand, wherein an expansion sleeve or ring (20) and the proximal end of a central axis (3) of the implant can be moved away from each other to exert traction on the flanges, via expansion arms, which causes the support arms to pivot, resulting in controlled expansion of the implant (1) between the folded configuration and the deployed configuration.

This invention provides a fully automatic medical screw torque testing device, belonging to the field of medical bone implant screw torque testing technology, comprising: a housing; a main shaft and a clamping fixture arranged opposite to each other inside the housing; the clamping fixture being movable to approach the main shaft; a rotatable first annular disk on one side of the main shaft for storing the main shaft head; the main shaft head stored on the first annular disk, and a first conveying mechanism on one side for conveying the main shaft head; a rotatable second annular disk on one side of the clamping fixture; a clamping shaft stored on the second annular disk, and a second conveying mechanism on one side for conveying the clamping shaft; this invention utilizes a screw feeding mechanism, a first conveying mechanism, and a second conveying mechanism to achieve automatic loading and unloading, eliminating the need for manual screw clamping and judging the relative positions of various components, reducing human interference factors, improving testing efficiency, and making the test results more accurate.

The present invention relates to an implant, a system and a manufacturing method for veterinary orthopedic surgery, for restoring volume and / or geometry to a bone by expansion, wherein at least two faces of the implant each comprise a plate, bringing the distal (12) and proximal (11) ends toward one another generating pivoting of the support arms, thereby causing the plates to move away from one another and consequently the implant to expand, characterized in that an expansion sleeve or ring (20) and the proximal end of a central axis (3) of the implant are movable away from one another in order to exert traction on the plates via expansion arms, which generates pivoting of the support arms so as to result in controlled expansion of the implant (1) between the folded configuration and the deployed configuration.

Methods of determining the position and orientation of an implant within a bone structure during a surgical procedure utilizing intraoperative data collected without radiation-based imaging, and associated systems and devices are disclosed herein. In some embodiments, a representative method includes capturing intraoperative data of the implant and the bone structure, wherein the bone structure has a portion external to the bone structure and visible in the intraoperative data. The method can further include registering the visible portion of the implant in the intraoperative data to (i) a three-dimensional model of the implant and (ii) initial image data of the bone structure. The method can further include determining the position and orientation of the implant relative to the bone structure based on both registrations.