220 results about "Bone implant" patented technology

A high-performance near-pure zinc alloy, a preparation method therefor and a use thereof, relating to the technical field of zinc alloys. The alloy component is that the content of Zn is greater than or equal to 99.5%, and the remaining trace alloy elements include at least two of the following 14 elements: Mg, Mn, Li, Cu, Ag, Ca, Sr, Fe, Zr, Ti, Al, C, Ga, and Si. The alloy has the yield strength ≥ 250 MPa, the tensile strength ≥ 320 MPa, the elongation ≥ 25%, the mechanical property change during one year of room-temperature storage ≤ 5%, the maximum bending force ≥ 2 kN, the stress corrosion sensitivity factor ≤ 15%, the size of corrosion pits after 60 days of immersion ≤ 15 μm, and the standard deviation of the size of corrosion pits ≤ 3 μm. The alloy is suitable for the preparation of biodegradable stents, bone implant devices, medical staplers or anastomotic nails for intestines, blood vessels or nerves, vascular clamps, guided bone or tissue regeneration membranes, heart valve protheses, dura mater repair membranes, soluble bridge plugs and fracturing balls for oil drilling, zinc alloy die castings, electroplated zinc materials, building zinc materials, battery-grade zinc, printing-grade zinc, and zinc-based brazing alloys.

The invention discloses a method and a system for testing corrosion fatigue of a bone implantation device under a pathological condition, and relates to the technical field of orthopedic medical device evaluation, and the method comprises the following steps: constructing a dynamic load spectrum database covering physiological and pathological states; in-vitro reproduction of a dynamic mechanical environment borne by the bone implantation instrument in physiological and pathological states is completed through a multi-axis servo system; and acquiring service state data of the bone implantation instrument, and analyzing the service state data of the bone implantation instrument to obtain coupling experiment data. According to the invention, the defects of single load mode and environment simulation distortion in the traditional test method are overcome, high-fidelity simulation and comprehensive monitoring of the corrosion fatigue behavior of the bone implantation device under the pathological condition are realized, the consistency of the in-vitro test result and the in-vivo actual service performance is improved, and the application prospect is wide. And a scientific and unified evaluation basis is provided for material screening, structure optimization and service life evaluation of different types of bone implantation instruments.

The invention relates to the technical field of bone implants for minimally invasive surgery, and particularly discloses an implant for percutaneous minimally invasive thoracolumbar vertebral fracture, which comprises a vertebral body forming body, the vertebral body forming body comprises a vertebral body forming body head and a plurality of blade parts arranged at the rear end of the vertebral body forming body head in a surrounding manner, the vertebral body forming body head is provided with a needle guide hole penetrating along the axial direction, and the needle guide hole is communicated with the blade parts; a containing cavity is defined by the blade parts; the front end of the threaded guide rod and the head of the cone forming body are integrally formed, the needle guide hole penetrates through the threaded guide rod in the axial direction, and the rear end of the threaded guide rod extends out of the containing cavity; the pedicle screw is provided with a threaded hole penetrating in the axial direction, the threaded hole is in threaded connection with the threaded guide rod, the pedicle screw comprises a screw head and a threaded part arranged at the rear end of the screw head, and the screw head is arranged in the containing cavity and expands the blade part. According to the implant for the percutaneous minimally invasive thoracolumbar vertebral fracture, surgical wounds are reduced, the vertebral restoration effect is good, the stability of a vertebral formed body is guaranteed, and the surgical time can be saved.

The invention discloses a bionic heterogeneous composite structure bone implant and a preparation method thereof, and relates to the technical field of medical implants.The bionic heterogeneous composite structure bone implant comprises an inner-layer cross-shaped structure, a middle-layer negative Poisson's ratio structure and an outer-layer honeycomb structure, and the cross-shaped structure, the negative Poisson's ratio structure and the honeycomb structure jointly form a bionic composite structure; and immersing the bionic composite structure subjected to double-network crosslinking into a drug-containing solution for post-treatment and drug loading to obtain the bionic heterogeneous composite structure. According to the invention, bionic adaptation and intelligent optimization of mechanical properties are realized, and the stress shielding problem is solved; according to the invention, osseointegration and vascularization processes are obviously accelerated and enhanced, and leap-type improvement of biological activity is realized; a novel intelligent treatment mode based on in-vivo microenvironment response is developed, and on-demand and accurate drug delivery is achieved.

The invention of the gradient porous structured sacral prosthesis and the manufacturing process aims to create an alternative replacement for bone loss in patients who require bone replacement. The gradient porous structured sacral prosthesis consists of an artificial bone fragment, a metal rod, and a set of screws for fixing the fragments. The manufacturing process consists of seven steps: Identifying the position and boundaries of the bone, First-step topology optimization, Second-step topology optimization, Defining the structural pattern and unit cell size, Designing the artificial bone implant, Mechanical performance testing of the implant, and Fabrication of the sacral implant. The devices and processes according to the present invention are clearly sequenced and characterized. Modification or change in the manufacturing sequence or use may reduce the capabilities of the present invention or make it unusable for the purposes of the present invention.

The invention belongs to the technical field of biological materials, and discloses a PEEK bone implant material of a piezoelectric catalysis biological heterojunction and a preparation method of the PEEK bone implant material, the material comprises a PEEK bone implant loaded with the biological heterojunction, the biological heterojunction is composed of BiVOO and a chalcogenide calcium compound in a molar ratio of 1-3, and the chalcogenide calcium compound is calcium sulfide, calcium selenide or calcium telluride; during preparation, the BiVO / CaX biological heterojunction is firstly prepared by a hydrothermal method or an in-situ composite method, then PEEK is sequentially subjected to acetone, ethanol and deionized water cleaning, sulfuric acid ultrasonic treatment for 5-10 minutes and dopamine modification, the biological heterojunction is in contact with the modified PEEK at 4 DEG C for 12 hours to complete loading, and improvement means can be introduced into part of schemes. The material has the acoustic catalytic antibacterial function and the bone repair promoting function, the antibacterial effect can be regulated and controlled through ultrasound, the process is simple, and the reaction condition is mild; the multi-drug-resistant bacterial infection can be dealt with, and the heterojunction loading stability and the material cell compatibility are improved.

The invention discloses a magnesium-titanium composite material with an interpenetrating phase structure for bone implantation, the magnesium-titanium composite material is formed by interpenetrating a reinforced phase made of a titanium alloy material and a matrix phase made of magnesium or a magnesium alloy material, and the reinforced phase and the matrix phase are respectively kept continuous in a three-dimensional space; a reinforcing phase and a matrix phase of the magnesium-titanium composite material have gradient structures in the radial direction; the invention further discloses a preparation method of the interpenetrating phase structure magnesium-titanium composite material for bone implantation. According to the magnesium-titanium composite material disclosed by the invention, the structure is designed into a structure in which the reinforcing phase and the matrix phase are three-dimensionally continuous and interspersed with each other and the two phases are in gradient in the radial direction, so that the magnesium-titanium composite material implant and healthy bone tissue at a bone defect part of a patient realize good biomechanical adaptation; the material is suitable for being used as a bone implant in the field of biomedical metal materials.

The invention discloses a bark crack bionic lattice structure design method based on a three-period minimal curved surface, a bark crack bionic lattice structure and a bone implantation stent. The bark crack bionic lattice structure design method comprises the following steps: S1, constructing a parent lattice structure by adopting a three-period minimal curved surface function; s2, crack characteristics are constructed in the matrix lattice structure through a bidirectional offset contour surface method, a bark crack bionic lattice structure is formed, and the crack size and the relative density are controlled through offset parameters; s3, the relative density of the bark crack bionic lattice structure is calculated through triple integration, and the volume fraction of the generated model is controlled; and S4, crystal orientation design and rotation angle design are conducted on the bark crack bionic lattice structure, so that the elastic modulus and mass transfer performance of the bark crack bionic lattice structure are regulated and controlled.

The invention discloses a bionic Voronoi-nickel titanium-hydrogel heterostructure implant and a preparation method thereof, and relates to the technical field of bone implantation, the construction of a Voronoi porous structure and the preparation of a bionic Voronoi-nickel titanium skeleton are completed through an innovative design method by referring to the structural concept of human bone trabecula, and then the bionic Voronoi-nickel titanium skeleton is used as a substrate to prepare the bionic Voronoi-nickel titanium hydrogel heterostructure implant. And preparing the bionic Voronoi-nickel titanium-hydrogel heterostructure implant by adopting a drying gel forming method. The implant integrates the mechanical advantages of high strength and low modulus of the nickel-titanium alloy and the structural characteristics of high connectivity and high specific surface area of the bionic Voronoi porous structure, the defect that hydrogel is weak in bearing is effectively overcome, meanwhile, the hydrogel has the buffering and energy absorbing effects, multifunctional time sequence delivery and release of antibiosis, anti-inflammation and bone regeneration promotion can be achieved, and the requirements of all stages of bone repair are met.

In some embodiments, a bone implant for percutaneous use is provided. The bone implant comprises a head, a body adjacent to the head and a tip opposite the head. At least the head, body or tip is configured to contact bone. An expandable member contacts at least one of the head, tip or body and is movable from an unexpanded configuration to an expanded configuration when deployed at a bone implant site. In some embodiments, a system for percutaneous bone harvesting is provided.

A bone insert includes a cap having a convex top surface, an elongated stem, and a barrier between the cap and the stem. The stem of the bone insert is inserted into a hole formed in a host bone until the barrier is pressed against the exposed bone. The bone implant can be placed against a small focus contact point on the cap. Liquid cement can be injected into a space volume between the host bone and a bone implant. The cap can be made of a material and / or have surface features that create a strong bond with the cement when the liquid cement cures. The stem can be made of a material and / or have bone ingrowth surface features that create a strong bond with the bone.

The present application relates to the technical field of composite biological coating. Specifically, the present application relates to a hydrophobic composite layer on a medical degradable magnesium alloy substrate and a preparation method thereof. In the preparation method, firstly, a porous ceramic oxide layer is formed on the magnesium alloy substrate through micro-arc oxidation treatment, so as to reduce the corrosion rate of the magnesium alloy; then, a strontium-doped hydroxyapatite layer is prepared on the surface of the micro-arc oxidation layer using a chemical deposition method, so as to improve the biocompatibility of the magnesium alloy; finally, the magnesium alloy subjected to the micro-arc oxidation and chemical deposition treatment is immersed and pulled once or more times in a polylactic acid solution containing nano-hydroxyapatite, so as to form a hydrophobic polymer layer. The hydrophobic composite layer prepared by the present application improves the corrosion resistance and biocompatibility of the magnesium alloy at the same time. The present application also relates to a magnesium alloy implant product comprising the hydrophobic composite layer.

Disclosed herein are compositions and methods to create bone implants that are biocompatible and custom designed to implant in a bone lesion. The implant comprises a unique scaffolding customized to the bone lesion and combined with one or more specialized proresolving mediators (SPM). According to certain embodiments, the scaffolding matrix comprises an alloplastic material developed into a matrix and including one or more SPM including synthetic SPM and natural SPM wherein the SPM is released over time.

Provided is a total talar replacement prosthesis that has a metallic body shell and a metallic or biologic core, where the metallic body shell includes one or both of a removable calcaneus attachment and a removable navicular attachment. The attachments, when removed, exposes a respective calcaneus-facing surface or a navicular-facing surface that can enhance fusion to the respective bones, calcaneus and / or navicular.

A bone insert includes a cap having a convex top surface, an elongated stem, and a barrier between the cap and the stem. The stem of the bone insert is inserted into a hole formed in a host bone until the barrier is pressed against the exposed bone. The bone implant can be placed against a small focus contact point on the cap. Liquid cement can be injected into a space volume between the host bone and a bone implant. The cap can be made of a material and / or have surface features that create a strong bond with the cement when the liquid cement cures. The stem can be made of a material and / or have bone ingrowth surface features that create a strong bond with the bone.

This invention relates to the field of biomedical materials technology, specifically to a method and application for the fabrication of heterogeneous metal bone implants. The fabrication method includes the following steps: S1: obtaining a physical model of the bone implant; S2: generating an L-PBF printing file based on the physical model of the bone implant to obtain a porous model of the bone implant; S3: based on the L-PBF printing file, using multi-material laser powder bed melting technology, performing integrated multi-material L-PBF printing with two or more different metal powders having large differences in melting and boiling points to obtain a porous heterogeneous bone implant blank; finally, post-processing the porous heterogeneous bone implant blank to obtain a heterogeneous metal bone implant. The fabrication method of this invention solves the core technical problem of weak interfacial bonding and easy failure in multi-material implants, and also addresses the problem of large differences in melting and boiling points between two metal materials.

An expandable bone implant for human orthopaedic surgery for restoring the volume and / or geometry of a bone, to an orthopaedic system and to a method for manufacturing the implant which includes a hollow body formed by a sheet made of a biocompatible metal alloy, closed on itself in a sealed manner, between proximal and distal ends, having, in the folded configuration, a plurality of pairs of folds, each of the pairs having an antiform fold, referred to as convex, and possible persistence of a synform fold, referred to as concave, the folds lying on top of each other in the folded configuration so that the surfaces present between each of the convex and concave folds are rolled around the longitudinal axis, the sheet being plastically deformable to allow expansion of the implant from the folded configuration to the deployed configuration, when a fluid is injected into the implant.

This invention discloses a method for depositing hydroxyapatite in a three-dimensional porous sample, comprising: S1, pretreatment of the three-dimensional porous sample; S2, placing the three-dimensional porous sample in an O... 2 In a plasma spraying apparatus; S3, prepare SBF1, immerse the sample treated in step S2 into SBF1, seal the container tightly, and place it in an incubator. After immersion in SBF1, remove the sample, wash and dry it. SBF1 contains the following components: CaCl2, MgCl2·6H2O, NaHCO3, K2HPO4·3H2O, Na2SO4, KCl, and NaCl; S4, prepare SBF2, immerse the sample treated in step S3 into SBF2, seal the container tightly, and place it in an incubator at 37°C. SBF2 contains the following components: NaCl, CaCl2, and K2HPO4·3H2O; S5, remove the sample, wash and dry it to obtain a three-dimensional porous sample with deposited hydroxyapatite. The method provided by this invention uniformly deposits HA in the porous three-dimensional void surface, and the composite interface can accelerate early bone healing, increase the integration of the bone implant surface with the bone, and promote the early stability of the implant.

A bone implant may include a shaft having a proximal end, a distal end, a longitudinal axis, a proximal shaft portion, and a distal shaft portion. The proximal shaft portion may include a first minor diameter, and a first helical thread disposed about the proximal shaft portion defining a first major diameter. The first helical thread may include a first concave undercut surface. The distal shaft portion may include a second minor diameter, and a second helical thread disposed about the distal shaft portion defining a second major diameter. The second helical thread may include a second concave undercut surface. The first and second concave undercut surfaces may be angled towards the distal end of the shaft. The second minor diameter may be smaller than the first minor diameter and the second major diameter may be smaller than the first major diameter.

A surgical robotic system for executing a bone implant surgical plan—includes a surgical robot. The surgical robot includes a first robotic arm for manipulating a surgical tool during a surgical procedure at a surgical site. A control unit of the surgical robotic system includes a processor programmed to direct the surgical robot to position the surgical tool. The processor program includes instructions for executing an act of defining the location of the surgical tool with respect to the surgical site. The processor program also includes instructions for executing further acts of moving the surgical tool to a bone located within the surgical site, the location of which being predefined within the surgical plan, and of marking the bone with the surgical tool, the marking corresponding to the position of a bone implant to be implanted in the bone according to the surgical plan.

The present application relates to a kind of self-setting composite bone implants based on gallic acid complex salt and preparation method thereof, belong to bone repair material field.The present application is specifically related to a kind of self-setting composite bone implants, it is characterized in that, component A, component B and component C, the component A is gallic acid and the complex salt of at least two metal elements, wherein the at least two metal elements are the metal element of promoting bone tissue regeneration or the trace metal element required by human body, and the at least two metal elements include calcium, the component B is the complex of calcium / strontium chondroitin sulfate and calcium sulfate, and the component C is magnesium calcium hydrogen phosphate complex.The self-setting composite bone implant of the present application has the characteristics of antibacterial, anti-inflammatory, promoting osteogenesis, instant shaping and all degradation, can meet the clinical needs of bone tumor, bone injury and the like, has wide application prospect in various bone repair, reconstruction and replacement.

The application discloses a multifunctional antibacterial coating bone implant device based on a selective vacuum perfusion process and a preparation method thereof. The method comprises the following steps: 1) pretreating a titanium alloy base; 2) performing anodic oxidation treatment on the pretreated titanium alloy base to construct a nanotube structure on the surface of the titanium alloy base; 3) selectively coating the treated titanium alloy base with a hydrogel adhesive, then immersing the titanium alloy base in a povidone iodine mixed solution to perform vacuum perfusion, and performing post-treatment, then again performing selective coating, immersing the titanium alloy base in a solution containing a bone growth promoting factor to perform vacuum perfusion, and performing post-treatment, then again performing selective coating, immersing the titanium alloy base in a solution containing a blood vessel growth promoting factor to perform vacuum perfusion, and performing post-treatment; and 4) encapsulating the obtained sample surface with an in-situ self-polymerized polydopamine layer, washing and freeze-drying. The bone implant device has antibacterial, bone growth promoting and blood vessel growth promoting functions, and can greatly improve the curative effect on bone fracture symptoms accompanied by infection.

The described system designed to promote the biological attachment of fibrous connective tissue to a bone implant features a bone implant with a scaffold defining a porous attachment surface, a suction port, and a manifold that distributes a negative pressure gradient across the attachment surface. The system also includes an extracorporeal vacuum pump and a percutaneous suction hose connecting the suction port of the implant to the vacuum pump. The implant is placed in the patient's body with connective tissue applied over the attachment surface, and the suction hose is attached and connected to the vacuum pump. The vacuum pump, operating outside the body, creates a negative pressure gradient over an extended period, promoting the growth of slow growing Sharpey's fibres for superior biological integration. A highly vascularised tissue graft, such as a pedicled muscle flap, may be applied adjacent to the avascular tendon to enhance endogenous growth factor migration.

A modular bone implant for affixation to a bone having a bone end surface and a bone side surface oriented at an angle with respect to each other. The implant comprises an anchor seat with an inner seat surface configured for abutting the bone end surface, and an elongate stem extending from the anchor seat with a proximal end portion, a distal end portion and a stem long axis. The proximal end portion comprises a planar surface obliquely angled relative to the stem long axis and configured for positioned placement under the bone side surface. At least one fixating element extends from the anchor seat adjacent the stem, having a fixator long axis parallel to the stem long axis and a length shorter than that of the stem. The implant may include a connecting portion configured to breach the bone side surface for attachment to a bone plate, which may be covered by a fixation plate.

The application discloses a kind of medical degradable WE43 / Zn interpenetrating phase composite material with body-centered cubic porous structure as framework and a preparation method thereof.The composite material is composed of WE43 magnesium alloy framework and zinc matrix;The WE43 framework is a body-centered cubic topology structure prepared by using laser selective melting technology, the porosity is 80%, and the topology structure with different strut thicknesses of 0.6mm, 0.8mm and 1.0mm is densified at 350 DEG C low temperature quickly.The composite material utilizes the strong "space constraint effect" generated by the small strut network, not only avoids the generation of continuous brittle intermetallic compounds at high temperature, but also realizes excellent metallurgical bonding and stress transfer.The ultimate compressive strength of the material can be up to 276MPa, and the degradation is stable, the biocompatibility is good, the problems of insufficient strength of pure zinc and too fast degradation of magnesium alloy are effectively solved, and the material has wide application prospect in the field of medical load-bearing bone implants.

The present invention relates to a system and a method for planning veterinary orthopedic surgery, for restoring volume and / or geometry of a bone, by expansion of at least one expandable bone implant (1) between a folded configuration and a deployed configuration, the implant comprising a body extending along a longitudinal axis (L) between a proximal end (11) connectable to an implantation instrument (A) for holding the implant and a distal end (12) intended to be inserted first into the bone, wherein the system comprises a plurality of expandable bone implants (1) and at least one implantation instrument (A) corresponding to each of the implants (1) and at least one planning support presenting the implants (1) and instrument (A), with reference to at least one standardized classification of the various types of fractures identified, in particular vertebral compression fractures, the planning support being capable of being implemented in the form of a human-machine interface.

A method for treating an artificial bone implant with blood, according to the method bone material is placed in a container configured to be filled with blood, wherein the container comprises an opening and a cover configured to cover the opening of the container and a fixed separator that separates a bottom part and an upper part. The separator is provided with holes so that when the container is filled with whole blood, the blood in the bottom part is in full contact with the blood in the upper part, and wherein the bone material is in the upper part, on top of the separator.

The invention discloses a shapeable bone repair material capable of being implanted in a positioning manner and a preparation method thereof. The interior of the bone repair material is a core layer made of a gelatin, gallic acid and hydroxyapatite particle composite material, and the exterior of the bone repair material is a porous spongy collagen wrapping layer; the density of the wrapping layer is 20-100mg / cm < 3 >; the density of the core layer is 100-800 mg / cm < 3 >; and the particle size of the hydroxyapatite particles is 0.1-2 mm. The collagen sponge on the outer layer of the material wraps the gelatin / hydroxyapatite composite material, so that the problems of loose structure, weak binding force and displacement and powder falling after implantation of bone meal or collagen bone meal composite materials are solved, stimulation and trauma of bone meal particles to surrounding tissues can be avoided, and the conditions of bone meal discharge, bone grafting part collapse and the like are avoided. And in the self tissue regeneration process, the collagen component is degraded and absorbed, and the hydroxyapatite is fused with the new bone, so that bone regeneration is realized, and the success rate of tooth implantation can be improved.

Disclosed herein are a surgical system for patella tracking and a method for selecting a properly-sized patellar implant utilizing the same. The surgical system may include first and second trackers and a patellar tracking system. The first tracker may be configured to contact an unresected or a resected patella, and the second tracker may be configured to contact a bone. The patellar tracking system may be configured to track the first and second trackers during patellar flexion and extension to generate patellar range of motion and patellar trial range of motion. A method for selecting a patellar implant may utilize the first and second trackers and the patellar tracking system.