123 results about "Cancellous bone" patented technology

A method of implanting a shoulder prosthesis assembly is provided where the method includes advancing by rotation a base member, that includes a cylindrical member and a helical structure, into a resection face of a humerus of a patient such that the helical structure is submerged in and engages cancellous bone of and does not extend distally of an epiphysis of the humerus, the cylindrical member being accessible at the resection face of the humerus when the base member is so advanced; advancing a locking device into the base member until at least one elongate member spans a space between adjacent portions of the helical structure to contact the cancellous bone in the space; and inserting a retention portion of a reverse articular insert into the cylindrical member of the base member to directly connect the reverse articular insert with the cylindrical member of the base member.

The invention discloses a bone scaffold fusion design and preparation method based on mirror image registration, and the method comprises the steps: firstly, based on a three-dimensional medical image of a femoral defect region of a patient, combining an opposite-side complete femoral CT image, and achieving the automatic recognition and complementation of the defect region through the mirror image transformation and ICP registration technology; after defect boundary extraction is completed, three-dimensional reconstruction is carried out on the individualized outer contour of the left bone tissue, and an STL format model is exported. According to the femur functional partition characteristics, a Diamond structure is adopted in a cortical bone area to enhance mechanical support, and a Gyandroid structure is selected in a cancellous bone area to achieve porosity gradient filling, so that the permeability is optimized, and cell proliferation is promoted. Continuous transition among the structures is realized through a Sigmoid function, and the stability and the biological adaptability of the whole structure are improved. And finally, the stent model is subjected to selective laser melting, and a Zn-3Mg alloy material is utilized to complete printing manufacturing.

The utility model discloses a 3D printing porous pedicle screw which comprises a screw body part and a screw cap part, the screw body part comprises a cortical bone thread area close to one end of the screw cap part and a cancellous bone thread area far away from one end of the screw cap part, and a porous structure area is arranged at one end, not connected with the screw cap part, of the screw body part. The porous structure area comprises an inner core column extending in the axial direction of the nail body part, at least one reinforcing beam and a porous structure, the reinforcing beams extend outwards from the periphery of the inner core column, and the porous structure is annularly distributed on the outer periphery of the inner core column. The porous structure can efficiently induce bone tissue to grow in, the screw and a vertebral body are connected into a whole, stress is effectively dispersed, the stability of the screw is improved, the porous structure is arranged on the vertebral body at the front end of the screw, screw breakage caused by stress concentration of the screw in a vertebral pedicle area can be avoided, meanwhile, the stability of the screw can be better improved through the reinforcing beam, and the service life of the screw is prolonged. The possibility of fracture of a porous area of the screw is reduced, generalization performance is better, and the use experience feeling is improved.

The embodiment of the invention provides an intelligent bone drilling self-adaptive control method for a mechanical arm, which comprises the following steps: acquiring displacement deviation of the tail end of a drill bit of an orthopedic surgical robot, obtaining an error change rate through differential calculation, and combining a bone layer type as an input variable of a fuzzy controller and a feeding speed as an output variable; input variables are fuzzified through a membership function, and a fuzzy language variable set is obtained; according to the set and a preset rule base, constructing a multi-rule group structure comprising three types of scenes of free space, cancellous bone and cortical bone, and setting corresponding fuzzy rule subsets for different bone layers; designing a ''minimum-maximum'' rule activation and combination strategy for reasoning by adopting a Mamdani type fuzzy reasoning method according to fuzzification input and a multi-rule group structure, and generating a fuzzification output variable set; and defuzzification is performed through a gravity center method to obtain a continuous speed instruction, and dynamic regulation and control of the drill bit feeding speed are achieved. When approaching a penetration point, the device automatically decelerates and safely stops, so that the safety and accuracy of an operation are effectively guaranteed, and over-drilling injury is prevented.

Surgical systems and methods for manipulation of an anatomy that includes cortical and cancellous bone. A surgical manipulator has a robotic arm to move an instrument with an energy applicator. A sensor senses forces / torques applied to the energy applicator. Controller(s) obtain a tool path for the energy applicator to traverse. A segment of the tool path transitions into, or between, cortical bone and cancellous bone. The controller(s) control the manipulator to advance the energy applicator along the tool path according to a first feed rate to manipulate the cortical or cancellous bone and detect, with the sensor, a change in the forces / torques being indicative of the transition. In response to detection of this change, the controller(s) control the manipulator to advance the energy applicator along the tool path according to a second feed rate, greater / less than the first feed rate.

The invention relates to a spine bone structure and bone mineral density automatic measurement method based on a CT image. The method comprises the following steps: performing CT scanning on a phantom with known bone mineral density to obtain a real bone mineral density calculation formula; all CT images in the DICOM format are read, DICOM analysis is carried out, and three-dimensional CT value data and other main information of all the images are obtained; performing outer contour segmentation on the whole spine in the CT image by using a deep learning network to obtain an outer contour of each vertebral body in the image; the method comprises the following steps: carrying out preliminary segmentation on cortical bones and cancellous bones by adopting a dynamic threshold method aiming at each vertebral body, selecting a preliminarily segmented cancellous bone region, using a maximum connected domain algorithm in a three-dimensional direction, retaining a maximum connected region, and further measuring the bone mineral density, namely calculating overall topology parameters, the bone mineral density and the bone mineral content of the current vertebral body; calculating the rubbing parameters, the bone mineral density and the bone mineral content of the current vertebral cortical bone and cancellous bone; and measuring the content of the cross section of the cone.

The invention provides a natural bone repair material and a preparation method thereof. The material is animal cancellous bone inorganic salt particles or animal cancellous bone inorganic salt bone slices; the invention also relates to a preparation method of the natural bone repair material. The preparation method sequentially comprises the following steps: selecting materials, crushing, cleaning, removing organic matters, efficiently cleaning and drying, calcining and sterilizing. According to the method, inorganic base heating extraction and low-temperature calcination are adopted, so that the method is non-toxic, harmless, safe, efficient, low in organic matter residue and small in damage to the structure of a natural bone material, and the structure and morphology of the natural bone are better reserved; the defects of long construction period, low efficiency, high cost and the like existing in high-temperature calcination and organic reagent removal are avoided. The size of the bone repair material can be controlled, and the obtained bone repair material has certain mechanical strength, is not easy to break after being filled, and can play a good supporting role; and the material also has the advantages of high specific surface area, high porosity, low crystallinity, good hydrophilic performance, good biocompatibility and the like, and is suitable for bone defect repair.

An osteogenic composition comprises growth-factor augmented cortical bone and cancellous bone having viable endogenous osteogenic cells that remain adherent to the cancellous bone. The growth-factor augmented cortical bone comprises demineralized cortical bone amplified with growth factors derived from a demineralized bone, and the cancellous bone not having been subjected to a loosening agent. The osteogenic composition is cryopreserved or lyopreserved. A method for preparing an enhanced graft composition with improved osteoinductive properties includes processing demineralized cortical bone; solubilizing growth factors from demineralized bone; and mixing the demineralized cortical bone with the solubilized growth factors.

The invention discloses a bone-like osteoma microwave ablation thermal injury assessment method based on all-optical parameters, which comprises the following steps: respectively considering thermal injury models of cortical bone and cancellous bone under different microwave ablation conditions by constructing a simulation model conforming to bone tissue characteristics; according to the method, construction of an incomplete P5 approximation model is proposed, bone tissue all-optical parameter anti-construction research based on steady-state radiance is carried out, the accuracy is high, calculation is convenient, temperature parameters and biological tissue all-optical parameters are analyzed in a combined mode, a tissue thermal damage model of the temperature and tissue all-optical parameters is established through theoretical research, and due to the characteristics of different bone tissues, the tissue thermal damage model can be used as a tissue thermal damage model of the temperature and tissue all-optical parameters. The tissue types are considered in the thermal damage model, and effective bone tissue thermal damage factors are designed based on different tissues, so that the evaluation accuracy is ensured.

The invention relates to the technical field of cancellous bone scaffolds, and discloses a topological optimization-based cancellous bone scaffold reverse generation model determination method and device, in the method, a three-dimensional thin layer structure is subjected to topological optimization processing, and complex and irregular microstructure characteristics of cancellous bone tissues can be simulated. The first multi-channel mechanical nephogram and the second multi-channel mechanical nephogram are force-related features. And multi-modal data composed of the three-dimensional thin-layer structure, the initial simplified model, the first multi-channel mechanical cloud picture and the second multi-channel mechanical cloud picture is used as a training sample to train a potential map diffusion model, so that the model can obtain strong performance of outputting a cancellous bone scaffold result under the training of a multi-modal input condition.

The patent refers to a dental self-tapping implant comprising a body having a longitudinal body axis and a length, the body having a proximal neck portion, a proximal-central straight portion of substantially constant body diameter and a distal conical portion of decreasing diameter, the body comprising a core with a thread provided thereon, and a flute of circular arc shape formed in the thread which runs helicoidally around the core the flute having a longitudinal flute axis. The body has two segments: a cortical segment next to the proximal neck portion, a spongiosa segment extending the cortical segment the spongiosa segment including the distal conical portion, the sum of the cortical segment and the spongiosa segment being equal to the sum of the proximal-central straight portion and the distal conical portion; the flute is configured to run helicoidally around the core until it reaches the neck portion, so that the longitudinal flute axis forms a first angle with the longitudinal body axis along the cortical segment, and forms a second angle with the longitudinal body axis along the spongiosa segment; the first angle is larger than the second angle, the value of the first angle is directly proportional to the body diameter with a proportionality parameter within the interval [11;18], preferably within the interval [13,15].The patent further refers to a set comprising a dental self-tapping implant and a multi-step drill configured for the dental self-tapping implant, where the multi-step drill has four steps along the spongiosa segment, each step having a drill diameter and a step height; the drill diameters increase from the portion of the multi-step drill corresponding to the distal conical portion to the proximal-central straight portion; the body diameter is greater than the drill diameters at each step height; the step heights along the spongiosa segment have respective predetermined values irrespective of the body diameter; the drill diameters increase with the respective body diameter.

This invention provides an internal fixation device for cancellous bone, belonging to the field of medical device technology. It includes a fixation plate with a plurality of screw holes and positioning holes arranged in a linear array on its top outer wall; and a guide assembly connected to the fixation plate, used to guide the hollow self-drilling screws. By incorporating the guide assembly, this invention not only guides the hollow self-drilling screws, preventing them from deviating from their pre-operatively assessed position during insertion, thus affecting their fixation effect on the fracture site, but also holds the screws during the guiding process, preventing the screw head from tilting and protruding, which could cause skin irritation and affect postoperative recovery.

The invention relates to the technical field of bone repair materials, in particular to a horse antler powder support material preparation device and system, and the device comprises an ossification degree pretreatment unit, a crushing unit, a mixing unit, a printing unit and a regulation and control unit; the ossification degree pretreatment unit comprises a transmission table and a controller, a positioning conveying assembly is arranged on the surface of a transmission part of the transmission table, and a detection assembly and a cutting assembly are arranged on a support part of the transmission table; the preparation system comprises an ossification degree pretreatment module, an air pressure crushing module, a proportioning and mixing module, a 3D printing module and a degradation rate regulation and control module. According to the method, ossification degree grading pretreatment is carried out on the raw material antler, precise recognition and directional cutting are carried out on a cancellous bone region, a compact bone mass core is removed, and the problems of active ingredient fluctuation and non-uniform pore structure caused by individual difference of ossification degrees are solved.

The application relates to a medical orthopedic quick drill bit, which comprises a drill bit body composed of a drill bit part and a drill rod part, wherein the drill bit part is provided with circularly arranged cutting edges for bone positioning and hole forming, and the drill rod part is designed as a light rod; a connecting piece is connected with the drill bit body at one end and fixed with a driving piece at the other end, and the two are quickly separated through a split device containing a clamping piece and a disengaging piece, so that safe disconnection is ensured when the pressure of the medullary cavity or cancellous bone is abnormal. The application has the technical effects of improving the operation efficiency, enhancing the safety and reducing accidental injuries.

The invention relates to the technical field of medical instruments, in particular to an interbody fusion cage which comprises an interbody fusion cage body, the interbody fusion cage body is of a polyhedral structure and is implanted into the lumbar intervertebral space through an anterior lateral approach, and a screw channel and a connecting screw opening are formed in the front end position and the rear end position in the length direction of the interbody fusion cage body respectively; the screw channel is used for allowing screws to penetrate through the upper surface and the lower surface of the interbody fusion cage body, connected with the vertebral cancellous bone in a matched mode and fixed to the inner side of the lateral portion of the vertebral cancellous bone. The connecting screw is used for being connected with an installation instrument in a matched mode when the interbody fusion cage is implanted. By means of the screw channel, the fixing capacity of the interbody fusion cage can be effectively improved, better stability can be effectively provided for an OLIF operation through a proper implantation position and screw placement internal fixing operation, the occurrence risk of postoperative internal fixing related complications is effectively reduced, and the safety of the interbody fusion cage is improved. The effectiveness and the safety of the fusion cage in the lumbar vertebra front and outer side approach interbody fusion operation are improved.

The embodiment of the disclosure relates to a computer tomography image-based acetabular cup prediction system and method, and relates to the technical field of medical image analysis, and the user information and the computer tomography image of a target user are acquired; the computer tomography image is subjected to image segmentation, and an acetabular region of interest is acquired; the corresponding Hounsfield unit value and the acetabular center coordinates of each pixel coordinate are acquired based on the acetabular region of interest, the screening area of the acetabular cup is determined based on the acetabular center coordinates and the received screening conditions, the Hounsfield unit value corresponding to each pixel coordinate is processed based on a preset dynamic threshold method, and the cortical bone Hounsfield unit average value and the cancellous bone Hounsfield unit average value of the screening area are obtained; prediction analysis is carried out based on the user information and the cortical bone Hounsfield unit average value and the cancellous bone Hounsfield unit average value of the screening area, and a prediction result is generated, so that more objective and accurate acetabular cup stability evaluation can be provided based on the prediction result.

The invention provides a bone evaluation method based on neural network enhancement and finite element analysis. The bone evaluation method comprises the following steps: acquiring an ultrahigh-resolution CT image of a living vertebra; performing domain conversion processing on the CT image by adopting a generative neural network; carrying out resampling and segmentation on the enhanced CT image; constructing a bone trabecula microstructure model in the cancellous bone mask area; assembling the RVE unit and the cortical bone model into a complete vertebral finite element model, and applying a multi-working-condition load to the RVE unit to calculate anisotropic material parameters; and carrying out axial compression finite element analysis on the complete centrum model, and judging the bone health state. According to the method, information of two dimensions of bone mass and bone, especially contribution of a bone trabecula microstructure to bone strength, is comprehensively considered, bone degeneration and fracture high-risk patients can be recognized earlier, and a scientific basis is provided for clinical early intervention.

An intraosseous screw implant pertains to medical equipment. The device is made with a variable height of the single-thread profile (2). Within the full turns (8) of the screw line, projections (7) with an increased height of the thread profile (2) are localized. The projections (7) are intended to bear the immediate load of the orthopedic structure. The projections (7) are located on adjacent turns (8) and are mutually offset by an angle. In an alternative embodiment of the device, the projections (7) are located from each other through a turn (8). The method for installing the implant includes forming a bone bed in the form of a narrowing opening. The dimensions of the opening are selected based on the condition of free accommodation of the predominant part of the implant. The implant is inserted into the cavity of the bed with the projections (7) resting on the spongy bone layer. Then the implant is screwed into the bone with several turns for fixation. The shape of the implant is optimized based on the condition of intensification of osseointegration of the immediately loaded implant. Reduced traumatic effect of implant screw elements on bone while ensuring immediate biomechanical load. Compacted bone tissue particles in the chip groove (4) at the top of the implant. Increased reliability of osseointegration. Increased implant survival level.

The improved endoprosthetic device surface treatment encourages soft tissue attachment thereto. A porous mesh surface treatment creates on an outer surface of the endoprosthetic device a three-dimensional surface structure similar to cancellous bone. Suture attachment features are provided at various locations around the treated surface structure to initially affix a vascularized soft tissue to the treated surface. As the patient heals the soft tissue grows and infiltrates the porous mesh surface to achieve an attachment strength substantially equal to the surrounding tissue.

The invention provides a cancellous bone internal fixing device, and belongs to the technical field of medical instruments. Comprising a fixing steel plate, a plurality of screw holes and a plurality of positioning holes are formed in the outer wall of the top of the fixing steel plate, and the screw holes and the positioning holes are distributed in a linear array mode; and the guide assembly is used for guiding the hollow self-drilling screw, and the guide assembly is connected with the fixed steel plate. By arranging the guiding assembly, the hollow self-tapping screw can be guided, the situation that the fixing effect of the hollow self-tapping screw on the fracture position of a patient is affected due to the fact that the hollow self-tapping screw deviates out of the designated position of preoperative evaluation in the screwing-in process is avoided, the hollow self-tapping screw can be held in the guiding process, and the fracture position of the patient is not affected. In this way, the situation that the screw head protrudes due to inclination, skin irritation is caused, and then postoperative recovery is affected can be avoided.

The present application belongs to the field of foot and ankle surgical implant devices and biomedical material surface engineering technology, and discloses a tibial component of ankle prosthesis with a composite coating, which comprises: a metal substrate which is a bionic trabecular three-dimensional interconnected porous titanium alloy structure, the porosity is 50-80%, the average pore size is 400-900 mu m, and the connected porosity is greater than or equal to 85%, so that the elastic modulus is controlled in the range of 5-20 GPa, and is matched with the cancellous bone of the tibia; a composite functional coating is in situ grown on the surface of the metal substrate, and the composite functional coating comprises a bioactive layer and a functional ion doped layer. The tibial component of the present application comprises a porous titanium alloy metal substrate and a composite functional coating constructed in situ on the surface thereof, the porous titanium alloy substrate is designed in a bionic trabecular structure to form a three-dimensional interconnected porous structure, so as to provide an elastic modulus matched with the cancellous bone of the tibia and promote the growth of bone tissue.

A suture-tension-activated anchoring system for fixing soft tissue to bone, the system comprising: a unitary implantable anchor body defining a longitudinal axis and having a proximal and a distal section; a proximal head unit formed on the proximal part of the anchor body and configured to interact with at least one repair suture; a tubular body unit extending distal to the proximal head unit and defining an internal longitudinal bore; a plurality of radially expandable rib elements arranged on the distal section of the tubular body unit and movable between a folded and an expanded configuration; and an internal cone unit positioned within the internal longitudinal bore and mechanically connected to at least one repair suture.wherein the application of a tensile force to the at least one repair suture causes a proximal axial displacement of the inner conical unit relative to the tubular body unit, wherein the proximal axial displacement of the inner conical unit generates a radial outward movement of the plurality of fin units from the folded to the unfolded configuration, and wherein the radial outward movement of the plurality of fin units anchors the anchor body in the cancellous bone without the need for an external deployment tool.

The invention provides a dental implant which comprises an implant body, and an implant thread matched with an alveolar bone is formed on the outer side wall of the implant body. The implant thread is made of a non-absorbable material and has good mechanical strength and biocompatibility. The surface of the implant thread is covered with the absorbable alloy layer, and the absorbable alloy layer is designed to be in a sharp thread form, so that bone injury in the implanting process is reduced. The absorbable alloy layer can be slowly absorbed by the alveolar bone after being implanted, so that the pressure on the cancellous bone is slowly reduced, the bone tissue healing is promoted, the stability of the dental implant is gradually consolidated and maintained, the reduction of peripheral inflammatory response or foreign body response is facilitated, and the long-term stability of the dental implant after being implanted is finally improved.

The application relates to the technical field of bone imaging, and provides an ultrasonic cancellous bone imaging method based on full-wave inversion, which comprises the following steps: S1: setting an imaged bone phantom model, emitting an ultrasonic pulse signal, recording the ultrasonic pulse signal passing through the model, and sampling the signal as a simulation experiment wave field signal; S2: establishing a simulation wave field, setting an initial sound velocity model as a current sound velocity model; S3: based on the current sound velocity model, carrying out forward modeling on the simulation wave field, carrying out incremental extrapolation of the forward wave field signal along the propagation direction of the ultrasonic pulse signal, recording the simulation wave field signal after completing one round of emission-reception; S4: constructing a loss function, solving the loss function by using a conjugate gradient method, and updating the current sound velocity model; and S5: judging whether the loss function converges or not, and outputting the current sound velocity model if the loss function converges. High-resolution ultrasonic imaging of bone and microstructure is realized, and the demand of bone medical treatment and diagnosis with high precision requirements is met.

The invention discloses a preparation method of a heterogeneous bone-microporous metal implant composite material, and belongs to the technical field of biology. The method comprises the following steps: implanting a microporous metal implant into a cancellous bone of a heterogenous animal, carrying out osseointegration connection on the microporous metal implant and the cancellous bone of the heterogenous animal after 12 weeks to form an interface interpenetrating structure, taking out the microporous metal implant, retaining a peripheral bone with the thickness of 1-10mm, and then sequentially carrying out gradient decalcification and complete decellularization treatment to obtain the porous metal implant of the heterogenous animal. The heterogeneous bone-microporous metal implant composite material with high bone induction activity, strong osseointegration and low immunogenicity is obtained; according to the invention, a metal implant material is converted into a bioactive implant composite material, and a heterogeneous interface of the metal implant and a transplanted bone is converted into a homogeneous interface of a host bone or a transplanted bone and a transplanted bone, so that the clinical problem that the interface osseointegration of the transplanted bone and the metal implant is poor is solved.

The invention provides a bone tissue-imitating TPMS-Voronoi composite structure modeling method, which comprises the following steps of: firstly, delimiting design domains including a cubic design domain and a columnar design domain according to a selected overall dimension, and then forming a tubular design domain of a compact bone and a columnar design domain of a cancellous bone on the basis of the columnar design domain; based on the design domains, establishing a TPMS structure compact bone model and a Voronoi structure cancellous bone model respectively, and finally performing Boolean union operation on a mesh model of the TPMS structure compact bone and a mesh model of the Voronoi cancellous bone structure to form a TPMS-Voronoi composite structure model of the simulated bone tissue. According to the modeling method provided by the invention, the periodic regular structure and the randomly distributed porous structure are fused, the native bone tissue can be matched at the same time in the three aspects of stress environment, body fluid circulation and structural geometric characteristics, and the overall mechanical property of the composite structure is remarkably improved.

The application relates to the technical field of landing gears, in particular to a shock-absorbing landing gear imitating the head bone structure of a woodpecker and a preparation method, wherein the main body of the shock-absorbing landing gear is prepared from a TiAl alloy material, and the shock-absorbing landing gear comprises, from outside to inside, a strength layer, a buffer layer and a toughness layer; the strength layer imitates the hyoid layer of the head bone of a woodpecker; the buffer layer imitates the cancellous bone layer of the head bone of a woodpecker; and the toughness layer imitates the cerebrospinal fluid layer of the head bone of a woodpecker. The landing gear prepared by imitating the head bone structure of a woodpecker has excellent shock-absorbing and impact-resisting capacity; the landing gear is prepared by adopting a selective laser melting (SLM) technology, the number of connecting pieces in the landing gear is reduced, unnecessary assembly steps are saved, and assembly errors are reduced; the material and the part are integrally formed, and complicated preparation steps and machining processes are avoided.

The invention belongs to the technical field of teaching demonstration, and particularly discloses a bone nail installation demonstration device for orthopedic surgery teaching, which comprises a placement table and a bone nail body, a bone structure is arranged at the top of the placement table, a detachable installation block is arranged at the top of the placement table, and a shooting assembly is arranged on one side of the placement table. The mounting block is a transparent material component, and a connecting groove is formed in the bottom of the bone nail body; by arranging the bone structure, the composite mechanical environment of cortical bone-cancellous bone in the bone nail implanting process can be simulated, the inner diameter of the resistance increasing ring is smaller than that of the bone nail to simulate high-resistance cortical bone breakthrough feeling, the inner diameter of the connecting ring is larger than that of the bone nail to simulate the friction resistance feeling of the cancellous bone, and the bone nail pushes the plugging block to compress the first spring; the real dynamic resistance changing along with the implantation depth is provided, and the multi-level hand feeling simulation overcomes the defects that a traditional model is distorted in hand feeling and single in feedback.

The invention belongs to the technical field of biomedical materials, and discloses a bone tissue repair material for promoting vascularization and new bone generation and a preparation method thereof. The bone tissue repair material is composed of a decalcified bone matrix and a degradable biological source gel material. The repair material has a loose porous three-dimensional structure similar to that of natural cancellous bone, and the temperature-sensitive gel material filled in the pore structure of the repair material can form gel in situ in vivo and is attached to pores of a decalcified bone matrix, so that cell migration, adhesion and proliferation can be promoted, the degradation rate of gel in vivo can be reduced, and the repair material has a good application prospect. The continuous release of the pro-angiogenesis factor is ensured. Good biocompatibility is achieved, and cytotoxicity and immunogenicity are avoided; meanwhile, in the slow degradation process, angiogenesis promoting factors are continuously released for a long time, and angiogenesis and new bone generation are promoted. Therefore, the implanted biological scaffold prepared from the bone tissue repair material has excellent bone repair and regeneration promotion capability and wide application prospect.

The patent refers to a dental self-tapping implant comprising a body having a longitudinal body axis and a length, the body having a proximal neck portion, a proximal-central straight portion of substantially constant body diameter and a distal conical portion of decreasing diameter, the body comprising a core with a thread provided thereon, and a flute of circular arc shape formed in the thread which runs helicoidally around the core the flute having a longitudinal flute axis. The body has two segments: a cortical segment next to the proximal neck portion, a spongiosa segment extending the cortical segment the spongiosa segment including the distal conical portion, the sum of the cortical segment and the spongiosa segment being equal to the sum of the proximal-central straight portion and the distal conical portion; the flute is configured to run helicoidally around the core until it reaches the neck portion, so that the longitudinal flute axis forms a first angle with the longitudinal body axis along the cortical segment, and forms a second angle with the longitudinal body axis along the spongiosa segment; the first angle is larger than the second angle, the value of the first angle is directly proportional to the body diameter with a proportionality parameter within the interval (11; 18), preferably within the interval (13, 15). The patent further refers to a set comprising a dental self-tapping implant and a multi- step drill configured for the dental self-tapping implant, where the multi-step drill has four steps along the spongiosa segment, each step having a drill diameter and a step height; the drill diameters increase from the portion of the multi-step drill corresponding to the distal conical portion to the proximal-central straight portion; the body diameter is greater than the drill diameters at each step height; the step heights along the spongiosa segment have respective predetermined values irrespective of the body diameter; the drill diameters increase with the respective body diameter.