506 results about "Bone fracture" patented technology

The invention relates to the technical field of medical image processing and artificial intelligence, in particular to a multi-part fracture parallel recognition system and method based on a medical image, and the system comprises an image preprocessing module which is used for obtaining an original CT image sequence, carrying out the standardization processing of the original CT image sequence, and outputting a standardized three-dimensional image data body; the basic recognition enhancement module is used for processing the three-dimensional image data body and generating an enhanced feature map; the texture complexity evaluation module is used for processing the three-dimensional image data volume and generating a control signal; the self-adaptive recognition module is used for combining the three-dimensional image data body and the enhanced feature map, responding to the control signal, executing parallel recognition and outputting a parallel recognition result; the diagnosis report generation module is used for summarizing the parallel recognition results and generating a structured fracture diagnosis report, one-time and efficient parallel screening and diagnosis of multi-part fractures are achieved, and the clinical diagnosis efficiency and accuracy are improved.

The invention provides a spine centrum compression fracture recognition method and system based on artificial intelligence, and the method comprises the steps: receiving original spine CT sequence data, and outputting a preprocessed standardized image; inputting the preprocessed image into a three-dimensional U-Net + + network to obtain a centrum segmentation probability graph; outputting the segmented centrum set and the position code thereof; for each segmented centrum, extracting a corresponding area based on a centrum mask, and splicing all features to form a comprehensive feature vector of each centrum; inputting the three-dimensional image block of each vertebral body into an image flow network to extract visual semantic features; and automatically generating a structured PDF report. According to the spine centrum compression fracture recognition method and system based on artificial intelligence, the problem of image quality difference caused by different CT devices and scanning parameters is effectively solved through the multi-scale residual enhancement technology and self-adaptive window level adjustment, and standardized processing of images is achieved.

The invention relates to the field of medical imaging analysis, and discloses a bone trabecula feature construction method and system, and the method comprises the steps: preferentially extracting a fragile region from an obtained vertebral image sequence, and generating an initial feature set representing the stability of a fine-grained structure; performing coherence comparison on the initial feature set in a cross-slice dimension to obtain a composite feature vector capable of reflecting the vulnerability level of the structure; based on the composite feature vector, a connectivity change curve of the bone trabecula in a loading environment is extracted by adopting a multi-layer progressive clustering mode, and candidate bone trabecula units with potential micro-damage trends are marked; classifying the candidate bone trabecula units according to risk gradients, and reconstructing a bone trabecula local topology network with weight levels; and according to the local topology network, identifying high-risk nodes showing an imbalance tendency in a specific mechanical simulation period, and generating a feature construction path finally used for micro-fracture risk prediction. The method has the advantage of improving the micro-fracture risk prediction sensitivity.

The invention belongs to the technical field of biomedical materials and tissue regeneration, and particularly discloses hydrogel with a self-enhanced piezoelectric effect as well as a preparation method and application of the hydrogel. The hydrogel is prepared by taking microphone (MXene), cellulose nanofiber (CNF), tyramine grafted carboxymethyl cellulose (T-CMC) and regenerated silk fibroin (RSF) as main materials through an enzyme crosslinking reaction of horse radish peroxidase (HRP) and hydrogen peroxide (H2O2). The hydrogel has excellent mechanical properties, biocompatibility and safety, and can realize self-enhancement in vivo and generate stable piezoelectric signals. The piezoelectric stimulation can promote proliferation, migration and differentiation of osteogenesis-related cells and regulate and control a bone tissue microenvironment, so that formation and repair of new bones in a bone defect area are remarkably accelerated. The hydrogel can be used as an injectable or moldable bone tissue repair material, and is suitable for bone fracture, bone defect and other bone tissue regeneration scenes.

The invention relates to the technical field of clinical medicine, and discloses an intertrochanteric fracture postoperative progressive rehabilitation system, which comprises an intertrochanteric fracture comprehensive data acquisition module, a dynamic data monitoring module, a rehabilitation scheme generation module, a rehabilitation execution module, a rehabilitation mode adjustment module, a diet structure adjustment module and a rehabilitation interaction feedback module, the intertrochanteric fracture comprehensive data acquisition module is responsible for acquiring static and semi-dynamic data of a rehabilitation full cycle, the dynamic data monitoring module monitors physiological and motion change data of a patient in daily activities in real time, the rehabilitation scheme generation module generates a personalized stage rehabilitation scheme, and the rehabilitation execution module executes a full-process rehabilitation action. The rehabilitation mode adjusting module is used for adjusting a rehabilitation exercise mode, the diet structure adjusting module is used for optimizing a diet structure, and the rehabilitation interaction feedback module is used for collecting feedback so as to correct the scheme.

A self-contouring plate system for bone fractures comprises a plurality of rigid plate elements connected by ball-and-socket joints. Each plate element includes a ball at one end and a socket at an opposite end for receiving a ball from an adjacent plate element. A single fastener for each plate element serves the dual function of securing the plate to bone and compressing the ball into the socket to lock the joint. The fastener includes bone threads for engaging bone and a head with a lower surface that directly contacts and compresses the ball. The system allows initial flexibility for contouring to complex bone shapes, then locks into position when the fasteners are tightened. The length is adjustable by adding or removing plate elements. Each plate element maintains substantially uniform thickness without protruding elements, and the balls are solid spherical members without through-holes to maximize strength and range of motion.

The invention belongs to the field of biological products, and particularly relates to a bone glue product for preventing and treating osteoporosis and application, the bone glue comprises sheep bone glue (small molecules), pig bone glue (small molecules) and black pig bone glue (small molecules); five animals are beneficial, sheep and pigs are food beneficial to body health, bones are made into bone glue (small molecules) through modern production processes such as an enzyme preparation method and the like, the bone glue (small molecules) is easily dissolved in water and easily absorbed by a human body, can supplement colloid in the bones, is non-toxic and can be eaten for a long time; due to different yin and yang attributes, different types of osteoporosis patients can be prevented and treated; the traditional Chinese medicine also has good prevention and treatment effects on complications, fracture, hairline fracture, arthralgia and other bone diseases caused by osteoporosis; the compound can be applied to preparation of medicines, foods and health-care foods for preventing and treating osteoporosis.

The self-contouring plate system for bone fractures with anti-rotation stop allows a surgeon to bridge a bone fracture, primarily in bones of complex shape where the use of plates or screws is difficult. The self-contouring plate is formed from a series of similar or identical rigid elements, the elements able to bend and rotate with respect to each other. This flexibility is initially helpful as the surgeon contours the device to the shape of the bone. When the desired shape is reached, the elements are locked into place. The length of device is adjusted by adding or removing elements, much like a necklace. Each element of the self-contouring plate includes a ball that extends away from a body, a cavity for receiving the ball of the neighboring plate, and a screw to compress the ball within the cavity.

The invention relates to the technical field of orthopedic surgery, and discloses an orthopedic surgery real-time navigation system based on multi-modal image fusion and artificial intelligence. The multi-modal image fusion module is used for generating a three-dimensional skeleton and soft tissue fusion model for surgical navigation; the artificial intelligence analysis module is used for determining a fracture line, a screw implantation angle and a cutting track; the intraoperative tracking module is used for generating a real-time correction instruction; the verification updating module is used for carrying out rationality verification on the real-time correction instruction; if the inspection is not passed, an alarm mechanism is triggered, instantaneous motion state parameters of the surgical instrument are collected, the instantaneous motion state parameters are compared with the cutting track, and the correction instruction is updated according to the comparison result; and the execution module is used for driving the surgical instrument to execute the surgical operation according to the updating correction instruction. According to the invention, manual operation errors can be effectively reduced.

The invention discloses an intelligent bone fracture plate integrated with an optical fiber Fabry-Perot sensor and a healing monitoring method. The system comprises an intelligent bone fracture plate module, an in-vitro detection module and a data analysis module. The intelligent bone fracture plate module mainly comprises a bone fracture plate body, a diaphragm type optical fiber Fabry-Perot sensor packaged in a U-shaped groove in the bone fracture plate, and a subcutaneous coupling capsule connected through a leading-out optical fiber. The sensor converts mechanical strain of the bone fracture plate into optical signal change of the Fabry-Perot cavity. The in-vitro detection module is in wireless optical coupling with the subcutaneous coupling capsule through an external read-write equipment head of the in-vitro detection module, probe light is emitted, interference light signals are received and reflected, and the strain of the bone fracture plate is calculated through a spectrum analyzer / detector. And the data analysis module converts the strain data into a key load sharing ratio. By monitoring the trend that the ratio gradually decreases from the postoperation along with time and comparing the trend with a preset clinical threshold value, objective, quantitative, dynamic and non-invasive monitoring of the fracture healing process is achieved.

The auxiliary support comprises a bottom plate, one end in the bottom plate is rotationally connected with a fixed hinge shaft, the two sides of the fixed hinge shaft are hinged to one ends of movable connecting rods respectively, and the other ends of the movable connecting rods are rotationally connected with the two ends of a movable hinge shaft respectively. The middle of the supporting shaft is fixedly connected with a connecting base, one end of the connecting base is fixedly connected with one end of a threaded rod, and the other end of the threaded rod is connected with one end of an inner threaded cylinder in a sleeved mode through a threaded structure. The other end of the internal thread cylinder is rotationally connected with a clamping block, the clamping block is clamped and matched with a clamping groove, and the clamping groove is concavely formed in the middle of the top surface of the bottom plate; sliding openings are formed in the two sides of the bottom plate respectively, adjusting bases are slidably arranged in the sliding openings, one ends of the adjusting bases are hinged to one ends of supporting connecting rods, and the other ends of the supporting connecting rods are hinged to one sides of movable connecting rods respectively.

The invention relates to the technical field of biology, in particular to application of a GGPS1 activator, a pharmaceutical composition, a kit and a method. The invention relates to bone metabolism regulation and bone regeneration. It is found that improvement of GGPS1 expression / activity can activate TGF-beta / Smad2 / 3 by down-regulating LTBP1, so that human bone marrow mesenchymal stem cells are converted from adipogenesis to osteogenesis, and bone formation and bone defect repair are promoted. The invention provides a drug containing a GGPS1 activator and a controlled release composition for implantation, which are used for osteoporosis, bone mass reduction, delayed fracture healing and the like. The invention also provides an in-vitro screening and evaluation method and a detection kit, and the indexes such as p-Smad2 / 3, alizarin red, oil red O and the like are used for judgment. The invention realizes upstream heavy balance and has the advantages of bone promotion and fat suppression.

The inventors discovered that calcitonin gene-related peptide (CGRP) inhibitors reduce pain caused by bone fracture without impeding healing of the fracture. Accordingly, disclosed herein are methods for treating pain in a subject that has sustained a bone fracture, and the methods comprise administering a therapeutically effective amount of a CGRP inhibitor to the subject.

The application relates to the technical field of big data processing, in particular to a fracture treatment scheme operation scheme simulation system based on big data analysis, which comprises a data preprocessing module, an adversarial network module and a model training and optimization module; a plurality of heterogeneous teacher models are used to pretrain a general large-scale fracture treatment data set, and fracture treatment decision knowledge learned by the plurality of heterogeneous teacher models is transferred to a student model for transfer learning. The application overcomes the contradiction between the small number of comminuted fracture cases (sample sparsity) of a single hospital and the high individualization of medical resources and capabilities (resource difference) by fusing the strategies of generative adversarial network (GAN) sample expansion and heterogeneous teacher model knowledge distillation transfer learning.

This invention provides a wire traction assembly for treating phalanx avulsion fractures, relating to the field of biomedical engineering technology. The wire traction assembly for treating phalanx avulsion fractures includes: a sleeve having a first end, a bent portion, and a second end; an insertion hole on the first end and a threading hole on the second end; a Kirschner wire for insertion into the insertion hole; and a tension band wire for attachment to the threading hole. This application achieves reliable wire fixation through direct attachment of the tension band wire to the threading hole, rather than by hanging it on the bent end of the Kirschner wire as in traditional techniques. Because the threading hole is a completely closed structure, the tension band wire cannot slip out of the hole under stress, effectively avoiding the risk of the wire slipping off at the smooth end of the needle in traditional techniques.

The utility model discloses an in-vitro sighting device for femoral trochanter fracture, and relates to the technical field of fracture surgical instruments. Comprising a matching frame, an extension structure, a guide cylinder and a developing needle, the matching frame is U-shaped, the corner of the matching frame is of a right-angle structure, the opening of the matching frame is placed towards one of two sides, a matching hole is formed in a middle plate between two side plates of the matching frame, the extension structure is arranged on the upper side of the matching frame, and the guide cylinder is arranged on the extension structure. The extending structure extends in the direction away from the matching frame, a guide cylinder is arranged on the extending structure and is arranged in the opening direction of the matching frame, a sliding hole is formed in the central axis of the guide cylinder, and a developing needle is slidably connected into the sliding hole of the guide cylinder; through cooperation of the matching frame and the sighting device and the height of the extension structure, the developing needle in the guide cylinder is higher than the front side of the thigh and corresponds to the position of the guide needle to be placed through the sighting device, the position of the guide needle is prompted in a perspective mode, and damage to a patient caused by wrong position and repeated placement of the guide needle is avoided.

The application discloses a kind of elderly hip fracture surgery perioperative adverse event real-time monitoring system and method, it is related to perioperative monitoring technical field.The method includes: real-time acquisition perioperative monitoring data, carries out data pre-processing, and extracts benchmark feature;Identify the decline segment of cerebral oxygen saturation below benchmark feature, jointly assess the decline amplitude and persistence, obtain the weak trend characterization of brain oxygen;Analysis of the relative change characteristics of serum inflammatory markers, form the weak trend characterization of inflammation;Assess the deviation degree of vital signs relative to benchmark, obtain the vital signs fluctuation characterization, and further judge the delirium precursor risk, output risk prompt;Visual display various weak trend characterizations and delirium precursor risk, link label risk trigger information and contribution source.The present application solves the technical problems that the prior art is difficult to extract and identify early weak abnormal trend in perioperative multi-source physiological signals.

The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment non-soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of non-soft tissue (e.g. bone) when combined with a biocompatible matrix, preferably SIS. The invention further provides methods of using compositions comprising muscle-derived progenitor cells with a biocompatible matrix for the augmentation and bulking of mammalian, including human, bone tissues in the treatment of various functional conditions, including osteoporosis, Paget's Disease, osteogenesis imperfecta, bone fracture, osteomalacia, decrease in bone trabecular strength, decrease in bone cortical strength and decrease in bone density with old age.

Implant guides, devices, systems and methods for implants to correct bone deformities and fractures in the lower extremity are disclosed. Specifically, implant guides, devices, systems and methods used for implants to correct bone deformities and / or fractures in the foot and ankle are disclosed.

Implant guides, devices, systems and methods for implants to correct bone deformities and fractures in the lower extremity are disclosed. Specifically, implant guides, devices, systems and methods used for implants to correct bone deformities and / or fractures in the foot and ankle are disclosed.

The application is suitable for the technical field of medical devices, and provides a bone fracture reduction device, which comprises a linear motion mechanism, a parallel mechanism and a fixing part. The parallel mechanism comprises a first motion assembly, a second motion assembly and a third motion assembly, and the first motion assembly, the second motion assembly and the third motion assembly are all installed on the linear motion mechanism. The fixing part is provided with a first connecting end, a second connecting end and a third connecting end. The first motion assembly is movably connected with the first connecting end, the second motion assembly is movably connected with the second connecting end, the third motion assembly comprises a first end and a second end, the first end is movably connected with the linear motion mechanism, and the second end is movably connected with the third connecting end. Through cooperation between the linear motion mechanism and the first motion assembly, the second motion assembly and the third motion assembly, the fixing part has three rotations, three movements and six degrees of freedom, so that the flexibility of the bone fracture reduction device is higher, and the treatment effect is better.

The application belongs to the technical field of medical image processing, and particularly relates to a kind of bone fracture block automatic reduction methods based on medical image;Including: obtaining the three-dimensional medical image data and three-dimensional label data after fracture of the object to be processed, and pre-processing the three-dimensional medical image data after fracture;The three-dimensional medical image data after fracture is input into the fracture surface segmentation model trained, and the main bone surface area and fracture block surface area are obtained;Three-dimensional coordinates are extracted and main bone surface point cloud and fracture block surface point cloud are constructed;Iterative closest point registration is carried out on the two kinds, and the cumulative rigid body transformation parameter is obtained;The voxel coordinate set corresponding to the fracture block is determined, and the voxel coordinate set is subjected to spatial transformation using the cumulative rigid body transformation parameter, to obtain the three-dimensional label result after reduction;The application can simultaneously complete the problems of automatic identification of fracture section and automatic solution of fracture block reduction posture, improve the degree of automation, result stability and interpretability of fracture block reduction process.

The present invention relates to a bio-resorbable calcium composite lag screw to achieve compression in small bone fractures. The design features allow for reliable insertion reducing the risk of fracture by having an internal geometry of the screw wherein an inserter or driver used to insert the screw applies force only to the threaded portion of the screw distal from the inserter or driver, reducing the risk of screw breakage on insertion.

The utility model provides a controllable micro-motion elastic internal fixation device with a bidirectional locking pressing plate structure, and belongs to the technical field of orthopedic medical instruments. Comprising a plurality of bridging rods; and the two end blocks are arranged at the two ends of the bridging rod. A stable frame structure is constructed through the combination of the bridging rod, the end block and the fixing screw, a fracture part is effectively connected and fixed in the axial direction, then a bidirectional locking mechanism is formed through the upper pressing plate, the lower pressing plate, the adjusting lead screw and the locknut, and the fracture part is locked by screwing the locknut. The distance and pressure between the pressing plates can be accurately adjusted and locked, dynamic force generated by factors such as muscle contraction and limb movement can be effectively resisted in the long-term use process, the pressing plates are prevented from loosening or displacing, and it is ensured that the fixing device always keeps the stable fixing effect; and the problems of poor fracture healing or malformation healing and the like caused by fixation failure are avoided.

Disclosed herein is a method for manufacturing a composition promoting recovery from a bone fracture, the method including preparing a mixture of Angelica gigas, Cnidium officinale, Phlomis umbrosa, Astragalus membranceus, Amomi fructus, Citri unshius pericarpium, Drynariae Rhizoma, Codonopsis Pilosulae Radix, frankincense, and myrrh, aging the mixture, smoking the mixture, drying the mixture and grinding the dried mixture into a powder, and extracting a liquid from the powder.

This invention relates to the field of medical devices and discloses an auxiliary tool for closed reduction of humeral fractures, comprising: a fixation body having a reduction channel formed inside, wherein at least two sides of the fixation body are respectively provided with openings communicating with the reduction channel; and a reduction module that can enter the reduction channel from any of the openings, wherein the reduction module can move and be positioned along a direction close to or away from the central axis of the reduction channel, wherein there are multiple reduction modules. This invention inserts multiple reduction modules from different openings to construct a customizable, multi-point contact and support structure within the reduction channel, and does not require manual positioning or additional trauma to the injured limb, thus achieving less trauma, higher stability, and more flexible operation in assisting closed reduction of humeral fractures.

The utility model discloses a novel bone fracture plate for treating bone nonunion of humerus, which relates to the technical field of bone fracture plates, and comprises an internal connection rotating piece mounted in a bone fracture plate main body, according to the device, the internal connecting rotating piece is installed, the inclined face of the internal connecting rotating piece is matched with the angle adjusting piece with the inclined face, and therefore a doctor only needs to rotate the angle adjusting piece and the internal connecting rotating piece when needing to obliquely install a connecting screw, and the angle adjusting piece rotates around the axis (namely the rotating axis) of a connecting boss; meanwhile, the internal connection rotating part is rotated, so that the inclined plane position of the internal connection rotating part is spatially changed, the angle of the angle adjusting part of the inclined plane can be adjusted, the mounting angle of the connecting screw can be changed to a certain extent, the angle of the connecting screw of the device can be adjusted, and the device can be adjusted according to the age and the body shape of a patient. Therefore, a doctor can select a proper angle to obliquely hit a screw at a proper position to connect the screw.

The invention discloses a fracture early warning method and system for bone mineral density analysis based on an MV-CT image. The method comprises the following steps: acquiring an MV-CT image, and sketching a skeleton contour based on the MV-CT image to obtain a skeleton contour map; calculating CT value data of the skeleton contour map, converting a pixel CT value of the skeleton contour map into pixel bone mineral density value data, and generating a bone mineral density three-dimensional distribution model; summarizing the bone mineral density three-dimensional distribution models under a plurality of time nodes to generate a bone mineral density change curve; generating a pseudo-color difference chart based on the bone mineral density three-dimensional distribution model; and carrying out fracture early warning based on the bone mineral density change curve and the pseudo-color difference chart. According to the method, visual bone mineral density change distribution can be obtained, accurate information of bone mineral density change during radiotherapy is further obtained, and early warning prompt is given to possible fracture parts.

A device for rapid reduction and external fixation of a limb fracture comprises a C-shaped splint, a fixed splint, a reduction arc plate, and a limiting component. The limiting component includes a connecting frame and a connecting arc plate. An outer wall of the connecting frame is provided with a fixed pressing plate, and a bottom of the fixed pressing plate is provided with a positioning clamping plate. A plurality of positioning slots are provided in the connecting frame and the connecting shaft. The positioning clamping plate is fixedly sleeved in the positioning slots.

The utility model discloses a low-stress longitudinal pressurizing bone fracture plate which comprises a fixing plate, a mounting hole is formed in the fixing plate, a pressurizing hole is formed in the fixing plate, a sliding seat is slidably connected in the fixing plate in a sleeved mode, a rotating seat is rotatably connected in the sliding seat, an inner hexagonal groove is formed in the rotating seat, and a connecting rod is arranged in the inner hexagonal groove. The bottom of the rotating seat is fixedly connected with a rotating shaft, the rotating shaft is rotationally connected with the sliding seat through a bearing, and the outer side of the rotating shaft is connected with a connecting sleeve through threads. By designing the effect of the rotating seat, a tool is inserted into the inner hexagonal groove in a matched mode to drive the rotating seat to rotate, then rotation of the rotating shaft can be achieved, threaded movement of the connecting sleeve can be achieved through threaded connection of the rotating shaft and the connecting sleeve, and then movement of the pressurizing block can be achieved. The pressurizing block can penetrate out of the sliding seat and penetrate through the pressurizing hole to achieve longitudinal pressurizing work, and operation is convenient and fast.