The present disclosure relates to a
prosthesis (400) configured for implantation in a
carpometacarpal joint in the
wrist, the
prosthesis comprising a first and a second
implant part member (405a,b) configured to be screwed into a
radius and metacarpal bone respectively. Each
implant part member (405a,b) comprising an articulation member (420a,b) configured to be received in the
bone fixation member (410a,b) in a releasable manner. The articulation members (420a,b) comprise orientation pins (423) configured to be inserted into bore sections of the
bone fixation members 410a,b. When seated in the bore sections, the first portions of the articulation members (420a,b) with the orientation pins (423) are substantially centered along the central axes of the
bone fixation members (410a,b), thereby forming common central axes extending through the bone fixation members (410a,b) and the articulation members (420a,b). The
radius articulation member (420a) comprises a replacement
articular surface configured for articulation with a replacement
articular surface located on the metacarpal articulation member (420b). The
radius replacement
articular surface has (420a) a configuration that is asymmetric about the common central axis of the
radius bone fixation (410a) and articulation members (420a). The bore sections have cross-section (419) extending perpendicularly to the central axis defining a first polygonal outline (429). The orientation pins (423) have cross-sections defining a second polygonal
contour line, such that when the orientation pins (423) of the articulation members (420a,b) are seated in the bores of the bone fixation members (410a,b), rotation of the articulation members (420a,b) in relation to the bone fixation members (410a,b) is prevented.