382 results about "Fixation method" patented technology

A spine fixation assembly connecting a first vertebra to a second vertebra includes first and second mounting assemblies and a first spinal stabilization component. The first mounting assembly is configured to be attached to a first location of the first vertebra and includes a first bone anchor housing and first and second spinal stabilization component housings extending from the first bone anchor housing. The second mounting assembly is configured to be attached to a first location of the second vertebra and includes a second bone anchor housing and third and fourth spinal stabilization component housings extending from the second housing. The first spinal stabilization component includes an elongated body having a first end and a second end and is configured to connect the first mounting assembly to the second mounting assembly. The first spinal stabilization component housing is adapted to receive and connect to the first end of the spinal stabilization component and the third spinal stabilization component housing is adapted to receive and connect to the second end of the spinal stabilization component.

Novel implantable tissue fixation methods and compositions are disclosed. Methods and compositions of tissue, fixed using polymeric and/or variable length crosslinks, and di- or polymercapto compounds are described. Also described are the methods and compositions wherein the tissue is fixed using biodegradable crosslinkers. Methods and compositions for making radioopaque tissue are also described. Methods and compositions to obtain a degradable implantable tissue-synthetic biodegradable polymer composite are also described. Compositions and methods of incorporating substantially water-insoluble bioactive compounds in the implantable tissue are also disclosed. The use of membrane-like implantable tissue to make an implantable drug delivery patch are also disclosed. Also described are the compositions and methods to obtain a coated implantable tissue. Medical applications implantable tissue such as heart valve bioprosthesis, vascular grafts, meniscus implant, drug delivery patch are also disclosed.

An apparatus and method for treating and/or diagnosing a patient's eye. A light source produces fixation light and procedure (treatment and/or diagnosis) light. A scanning device deflects the fixation light to produce a fixation pattern of the fixation light on the eye, and deflects the procedure light to produce a procedure pattern of the procedure light on the eye. A controller controls the scanning device such that the fixation and procedure patterns move relative to each other, and/or the fixation pattern dynamically changes.

An implantable medical electrical lead for electrical stimulation of body tissue that includes a lead body extending between lead proximal and distal ends, at least one tine element that includes at least one flexible, pliant, tine, that is adapted to be folded inward and temporarily secured against the lead body using a temporary fixative, and at least one electrode, wherein the at least one electrode is distal of the at least one tine element on the lead body. A medical electrical stimulation system that includes an implantable pulse generator for providing medical electrical stimulation, and a medical electrical lead coupled to the implantable pulse generator for electrical stimulation of body tissue, the medical electrical lead including a lead body extending between lead proximal and distal ends. at least one tine element that includes at least one flexible, pliant, tine, that is adapted to be folded inward and temporarily secured against the lead body using a temporary fixative, and at least one electrode, wherein the at least one electrode is distal of the at least one tine element on the lead body.

A bone plate is provided for fixation of spaced vertebra. The bone plate has at least one through passage for securing the plate to bone with a bone fixation screw. The threaded shaft of a bone fixation screw is inserted through a bushing located in the through passage of the bone plate and the screw is thereby threadably secured to the underlying bone and the bushing is then compressed inward against the head of the screw with cams that are actuated by rotating the bushing in the through passage whereby the screw is locked relative to the bone plate. The bushing is not only compressed inwardly against the head of the screw but is also compressed downwardly by the cams into a seat to clamp separate elements of the bone plate together.

Artificial disc replacements (ADRs), including ADRs with plate-like extensions, can be bent at the junction of the plate-like extension and the ADR Endplate (EP), which allows customization of the ADR to better fit a patient's vertebrae. A hinge joint allows customization of the ADR to fit a patient's vertebrae better. Other embodiments of the ADR contain telescoping components which allow customization of ADRs to replace two or more adjacent discs. Plate-like extensions that inter-digitate facilitate ADR insertion at two or more adjacent levels of the spine. Mechanisms to prevent screws from backing out of the plate-like projections are also disclosed. Nitinol or other shape-memory materials may be used for such purpose. Various other anti-back-out and anti-extrusion mechanisms are disclosed, all of which are applicable to non-spine applications, including long-bone plates, and total hip, knee and other joint prostheses.

Embodiments of the present invention include devices and methods for aligning fragments of a fractured bone or for positioning bones. In some embodiments, fixation devices and anatomical features are modeled with the aid of a computer served over a network, and the model is used to determine how an actual fixation device should be configured to align or position the bones.

A method of treating a biological tissue including contacting the biological tissue with an aqueous sterilizing solution, and maintaining the aqueous sterilizing solution at a temperature of about 50° C. for a time period of about 1 to 2 days. The method of treating a biological tissue may be utilized as a terminal sterilization step in a method for fixation of biological tissues, and bioprosthetic devices may be prepared by such fixation method. The fixation method may include the steps of A) fixing the tissue, B) treating the tissue with a mixture of i) a denaturant, ii) a surfactant and iii) a crosslinking agent, C) fabricating or forming the bioprosthesis (e.g., forming the tissue and attaching any non-biological components thereto) and D) subjecting the bioprosthesis to the terminal sterilization method. The aqueous sterilizing solution may be glutaraldehyde of about 0.625 weight percent buffered to a pH of about 7.4.

The present invention relates to medical devices for repairing tissue and more specifically to devices which facilitate tissue regeneration and to surgical methods for the implantation and fixation of such devices. In one embodiment, the medical device is an elongate conduit that includes a longitudinal bore extending therethrough to facilitate the transfer of blood from a vascular region of tissue to a tear or damaged area located in an avascular and/or semi-vascular region of tissue. A filament and/or filaments are attached to the conduit and are positioned to secure the conduit and fixate the adjacent tear walls in mutual engagement. In another embodiment, a series of conduits are connected via a filament and/or filaments to facilitate the implantation of multiple conduits.

An implantable medical electrical lead particularly for stimulation of the sacral nerves comprises a lead body extending between a distal end and a proximal end, and the distal end having at least one electrode of an electrode array extending longitudinally from the distal end toward the proximal end. The lead body at its proximal end may be coupled to a pulse generator, additional intermediate wiring, or other stimulation device. A fixation mechanism is formed on or integrally with the lead body proximal to the electrode array that is adapted to be implanted in and engage subcutaneous tissue, particularly muscle tissue, to inhibit axial movement of the lead body and dislodgement of the stimulation electrodes. The fixation mechanism comprises a M tine elements arrayed in a tine element array along a segment of the lead proximal to the stimulation electrode array. Each tine element comprises at least N flexible, pliant, tines, each tine having a tine width and thickness and extending through a tine length from an attached tine end to a free tine end. The attached tine end is attached to the lead body from a tine attachment site and supports the tine extending outwardly of the lead body and proximally toward the lead proximal end. The M×N tines are adapted to be folded inward against the lead body when fitted into and constrained by the lumen of an introducer such that the tine free ends of more distal tines of more distal tine elements are urged toward or alongside the attached tine ends of the adjacent more proximal tines of more proximal tine elements, and the folded tines do not overlap one another.

The invention includes an implantable medical electrical lead for electrical stimulation of body tissue that includes at least one modifiable portion that exhibits a first configuration when exposed to a first temperature and a second configuration when exposed to a second temperature, wherein the second configuration of the modifiable portion exhibits a greater resistance to movement of the lead within the body tissue than does the first configuration, and the second temperature is higher than the first temperature; and at least one electrode configured to provide electrical stimulation of body tissue, wherein the lead has a proximal end and a distal end. Systems including leads of the invention and methods of implanting leads of the invention are also included.

The invention relates to a global navigation satellite system (GNSS) triple-frequency motion-to-motion positioning method. In the original epoch, the triple-frequency precision single-point positioning technology is adopted to obtain the coordinates of two movable carriers, one of the two movable carries is selected as the reference station for the triple-frequency double-difference position, the triple-frequency double-difference positioning technology is adopted to calculate the baseline component of the two movable carriers and the integer ambiguity resolution of the double-difference carrier phase, and the baseline component of the two movable carriers and the integer ambiguity resolution of the double-difference carrier phase are used as the constraint conditions for the triple-frequency precision single-point positioning in the subsequent epochs to improve the single-point position precision and the convergence speed thereof. The geometry-Base TCAR ambiguity resolution fixation method is adopted to calculate the triple-frequency integer ambiguity resolution. The three irrelevant combination observation values of the triple-frequency non-ionizing layer and the long wave-length and low noise carrier are adopted to detect and repair the cycle slip of the original observation data.

A fixation device configured to fix on a medium a resin fine particle that contains a resin, by providing a fixation fluid on the resin fine particle on the medium which fixation fluid contains a softening agent that softens the resin fine particle by dissolving or swelling at least one portion of the resin, water and a foaming agent that comprises a salt of aliphatic acid, wherein the fixation device comprises a foam-like fixation fluid producing part configured to produce a foam-like fixation fluid, a layer thickness controlling part configured to control a layer thickness of the produced foam-like fixation fluid, and a provision part configured to provide the layer-thickness-controlled foam-like fixation fluid on the resin fine particle on the medium.

An implantable medical electrical lead for electrical stimulation of body tissue that includes at least one modifiable portion that exhibits a permanent configuration and a temporary configuration, wherein the temporary configuration exists only when the surrounding magnetic field is increased, wherein the permanent configuration of the modifiable portion exhibits a greater resistance to movement of the lead within the body tissue than does the temporary configuration; and at least one electrode configured to provide electrical stimulation of body tissue, wherein the lead has a proximal end and a distal end. Systems, and methods of implanting the leads are also included in the invention.

A bone plate is provided for fixation of spaced vertebra. The bone plate has at least one through passage for securing the plate to bone with a bone fixation screw. The threaded shaft of a bone fixation screw is inserted through a bushing located in the through passage of the bone plate and the screw is thereby threadably secured to the underlying bone and the bushing is then compressed inward against the head of the screw with cams that are actuated by rotating the bushing in the through passage whereby the screw is locked relative to the bone plate. The bushing is not only compressed inwardly against the head of the screw but is also compressed downwardly by the cams into a seat to clamp separate elements of the bone plate together.

The invention relates to a method and a device for fixing cotton fabric reactive ink inkjet printing. The method comprises the following: (1) a step of pretreating fabric, which is to make thickener into stock thickener, dissolve alkaline agent, urea and antifoaming agent in water, add the alkaline agent, the urea and the antifoaming agent to the stock thickener, evenly mix the mixture so as to form a pretreatment solution, pad the fabric with the pretreatment solution and then dry the fabric; (2) a step of performing inkjet printing, which is to adopt reactive dye ink to perform inkjet printing to the pretreated fabric on a digital inkjet printing machine; and (3) a step of after-treating the fabric, which is to adjust humidity of the jet-printed fabric for 4 hours, adopt a contact-type dry-heat fixation device, regulate the temperature of a heating plate to be between 150 and 160 DEG C, set the treatment time to be between 40 and 80 seconds, complete fixation through contact-type dry-heat treatment, wash and dry or air the fabric, so as to obtain a finished product. The invention has the advantages of convenient operation of technological process, strong flexibility and high fixation rate, and solves the problems existing in small-batch steaming fixation.

This invention relates, e.g., to a composition that, at room temperature, when contacted with a sample comprising phosphoproteins, can fix and stabilize cellular phosphoproteins, preserve cellular morphology, and allow the sample to be frozen to generate a cryostat frozen section suitable for molecular analysis. The composition comprises (1) a fixative that is effective to fix the phosphoproteins, and that has a sufficient water content to be soluble for a stabilizer and/or a permeability enhancing agent); (2) a stabilizer, comprising (a) a kinase inhibitor and (b) a phosphatase inhibitor and, optionally, (c) a protease (e.g., proteinase) inhibitor; and (3) a permeability enhancing agent (e.g. PEG). Methods are described for preserving phosphoproteins, using such a composition. Also described are endogenous surrogate markers for monitoring protein degradation, including the loss of posttranslational modifications (such as phosphorylation), e.g. the following removal of a cell or tissue from a subject; and exogenous molecular sentinels (e.g. phosphoproteins attached to magnetic nanoparticles) that allow one to evaluate the processing history of a cellular or tissue population sample.

The invention discloses a non-aqueous media dye-fixation method suitable for reactive dye and belongs to the field of textile dyeing and finishing technologies. The dyeing method comprises the following steps: (1) applying a reactive dye solution onto textile; (2) carrying out dye fixation on the textile in anon-aqueous media after the application of the reactive dye solution; and (3) soaping, washing and drying the textile after dye fixation so as to obtain a dyeing finished product. As there is no need to add inorganic salt or other dyeing additives by the method, water for dyeing and dyeingwastewater are greatly reduced, and dye fixation rate is raised. After dye fixation, the non-aqueous media is easy to purify and recycle, thus truly realizing ecological dyeing of reactive dyes. Thedefect that traditional reactive dye dyeing wastewater is much and hard to process and dye fixation rate is low is changed.

A method of performing vertebral facet fusion by lateral approach and related devices. The lateral approach to facet fusion involves identifying the lateral mass and introducing any of the fixation methods known or described herein laterally at one or more facets through the use of a Kirschner wire guide, a cannulated bone drill and cooperatively cannulated staple guide. A surgical bone staple have a perforated bridge is used across the lateral facet joint where fixation is required. Where fusion is desired, a bone screw have lateral perforations of the shank is inserted through the cannulated staple guide and bridge perforation at the joint to promote fusion. A staple cap and graft container for overlay grafting may be utilized for additional fusion. The method involves less surgical time, reduced blood loss and discomfort for the patient as compared to the posterior approach.