Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

142 results about "Subcutaneous tissue" patented technology

The subcutaneous tissue (from Latin subcutaneous, meaning 'beneath the skin'), also called the hypodermis, hypoderm (from Greek, meaning 'beneath the skin'), subcutis, or superficial fascia, is the lowermost layer of the integumentary system in vertebrates. The types of cells found in the hypodermis are fibroblasts, adipose cells, and macrophages. The hypodermis is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. In arthropods, the hypodermis is an epidermal layer of cells that secretes the chitinous cuticle. The term also refers to a layer of cells lying immediately below the epidermis of plants.

Non-invasive, uniform and non-uniform RF methods and systems related applications

ActiveUS12558145B2ElectrotherapySurgical instruments for heating'Orange peel' skinFecal incontinence
Systems and methods utilizing RF energy to treat a patient's skin (e.g., dermis and hypodermis) or other target tissue including at a depth below a tissue surface (e.g., skin surface, mucosal surfaces of the vagina or esophagus) are provided herein. In various aspects, the methods and systems described herein can provide a RF-based treatment in which the deposition of RF energy can be selectively controlled to help ensure heating uniformity during one or more of body sculpting treatment (lipolysis), skin tightening treatment (laxity improvement), cellulite treatment, vaginal laxity or rejuvenation treatment, urinary incontinence treatment, fecal incontinence treatment, all by way of non-limiting examples. In various aspects, the systems can comprise one or more sources of RF energy (e.g., a RF generator), a treatment applicator comprising one or more electrode arrays configured to be disposed in contact with a tissue surface, and a return electrode (e.g., a neutral pad) to the tissue surface.
Owner:CYNOSURE INC

Analyte detection device mounting unit

The application discloses an analyte detection device mounting unit, a limiting groove is arranged on a shell, and a T-shaped structure sliding block is arranged on a parallel sliding block module correspondingly, the T-shaped structure sliding block is located in the limiting groove, and the T-shaped structure sliding block slides in the limiting groove when a mounting action is implemented. The cooperation of the T-shaped structure sliding block and the limiting groove can limit the parallel sliding block module, avoid deflection of the parallel sliding block module in the shell, guide the parallel sliding block module to slide in the shell, and thus make the sensor pierce into the subcutaneous tissue in a vertical direction, so that the mounting unit is simple in structure and convenient to use.
Owner:MEDTRUM TECH

Electroencephalographic monitoring sensor with intradermal needle

ActiveCN224403667UAvoid poor fit issuesPhysical medicine and rehabilitationNeedle puncture
The application relates to an electroencephalogram monitoring sensor with intradermal needles, comprising an electroencephalogram monitoring sensor body with a plurality of electrode pieces, one or more of the electrode pieces being provided with an intradermal needle, the intradermal needle being fixed to the middle part of the inner side or the outer side of the electrode piece and being electrically connected with the electrode piece; when the electroencephalogram monitoring sensor body is pasted on the forehead of a patient, the intradermal needle penetrates into the subcutaneous tissue; the electroencephalogram monitoring sensor with the intradermal needles can acquire electroencephalogram biological signals in a more direct mode, can better avoid the problem of poor adhesion when the electroencephalogram monitoring sensor is pasted on the forehead of a patient, and has certain application prospect.
Owner:SUZHOU SCI&TECH TOWN HOSPITAL

Cell implant including biodegradable porous microwell with stem cell-derived insulin-secreting cell aggregate supported therein, and use thereof

PendingUS20260076997A1Metabolism disorderPancreatic cellsInsulin Secreting CellPancreatic hormone
The present disclosure relates to a transplantable cell therapy product composition for diabetes mellitus that contains an aggregate of insulin-secreting cells derived from stem cells. In the present disclosure, an NF microwell array membrane was fabricated by applying a molding process to an electrospun, permeable, biodegradable polycaprolactone (PCL) NF membrane and thus allows gases and soluble factors to permeate therethrough. The NF microwell of the present disclosure could provide more nutrients to the iPSC aggregates than conventional impermeable PDMS microwells, thus enhancing survival and differentiation capabilities of the cells. Additionally, the NF membrane was attached singly to the subcutaneous tissue and to the surface of organs such as liver and peritoneum without the need for a fixing material or separate sutures and was integrated with surrounding tissues, resulting in higher insulin secretion than PDMS microwells. Therefore, the present disclosure can be effectively utilized as a composition for the prevention or treatment of diabetes.
Owner:POSTECH ACADEMY INDUSTRY FOUNDATION +2

Devices, systems, and methods for treating vessel wall openings

Devices, systems, and methods for treating vessel openings are disclosed herein. According to some embodiments, a device for treating a vessel opening comprises a housing configured to be positioned within an opening in subcutaneous tissue proximate the vessel opening. The housing can comprise an inner wall and an outer wall. The inner wall can define a first lumen configured to receive an elongate member therein and the inner and outer walls can define a second lumen configured to receive an adhesive. The outer wall of the housing can define one or more apertures extending radially from the second lumen to an environment external of the housing. The device can comprise an actuator configured to be received within the second lumen. Movement of the actuator can force the adhesive to move through the aperture to the external environment and into an extravascular space within the subcutaneous tissue proximate the vessel opening.
Owner:MEDTRONIC INC

Swelling microneedle patch and preparation method thereof

The invention discloses a swelling microneedle patch and a preparation method thereof. The swelling microneedle patch comprises a backing and a swelling microneedle array adhered to the backing, the swelling microneedle array comprises a plurality of microneedles; the microneedle is in the shape of a cone or a rectangular pyramid; the height of the microneedle is 100 to 1000 [mu] m; the diameter of the tip end of the microneedle is 5-30 microns; the diameter of the bottom of the microneedle is 50-500 [mu] m; and the center-to-center distance between every two adjacent microneedles is 50-2000 microns. The swelling microneedle patch provided by the invention can overcome the barrier action of cuticle to penetrate subcutaneously and absorb subcutaneous tissue interstitial fluid, and is simple in preparation process, low in cost and high in universality. The patch is combined with a colloidal gold lateral chromatography test strip, so that the limitations that in-vitro diagnosis of infectious diseases depends on a blood sample, professional medical personnel are needed for operation, the subject compliance is poor and the like can be solved, and the patch is suitable for rapid screening and diagnosis of the infectious diseases.
Owner:TSINGHUA SHENZHEN INTERNATIONAL GRADUATE SCHOOL

Cosmetic device

This utility model discloses a beauty device, relating to the field of medical aesthetics technology. The beauty device includes a shell assembly, an adsorption pump, a circuit assembly, and a first electrode pair. The shell assembly has an adsorption chamber, an air intake, and an action port. The first electrode pair includes a first positive electrode and a first negative electrode located at the action port, which are arranged opposite to each other and electrically connected to the circuit assembly. Both the first positive and first negative electrode include a main body segment and an inclined segment. The main body segment is located on the outer end face of the action port, and the inclined segment extends from the action port to the inner wall of the adsorption chamber. The adsorption pump adsorbs the dermis and subcutaneous tissue of the target treatment area into the adsorption chamber, placing it between the two opposing inclined segments. This utility model improves the structure of the beauty device, significantly increasing the effective depth of action, reaching the deep dermis and even subcutaneous tissue; the effective range of action is also significantly increased; and the effective depth and range of action are adjustable.
Owner:GUANGDONG ACE TEC CO LTD

A data processing method and system for body surface wounds and subcutaneous tissue injuries

This invention discloses a data processing method and system for surface trauma and subcutaneous tissue injury. The method includes: using millimeter-wave radar to perform non-contact signal acquisition of the trauma area to obtain echo signal information; performing two-dimensional data analysis and processing on the echo signal information to obtain target trauma signal information; and performing three-dimensional data analysis and processing on the target trauma signal information to obtain target identification result information.
Owner:UNIV OF SHANGHAI FOR SCI & TECH +1

drag hook (bent)

1. Name of the product in this design: Hook (bent type). 2. Intended use of this design: for subcutaneous tissue surgery. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key features: the front view.
Owner:石臣磊

Removal device for minimally invasive rejection of subcutaneous tissue

The utility model relates to a removing device for removing subcutaneous tissue in a minimally invasive mode, and belongs to the technical field of medical instruments. Comprising a handle which is provided with a mounting groove; the first end of the connecting assembly is detachably connected with the mounting groove; the planing piece is detachably arranged at the second end of the connecting assembly and used for removing subcutaneous tissue. According to the internal fistula subcutaneous tissue planer, the planing sheet extends into the subcutaneous tissue for planing, part of the subcutaneous tissue is cut off, and the thickness of the internal fistula blood vessel talus is reduced.
Owner:WENZHOU GERIATRIC HOSPITAL CO LTD

kit

ActiveCN116370693BActs as a filling and firming agentContinuously fills and tightensSuture equipmentsBio-packagingHuman bodyFibroblast
The present disclosure relates to a kit. The kit of the present disclosure comprises: a kit body comprising a needle tube and a needle, the first end of the needle being mounted to the needle tube; and a catabolic filling thread comprising a first segment and a second segment connected to each other, at least a part of the first segment being located inside the needle, and at least a part of the second segment being located outside the needle, wherein the catabolic filling thread is a thread made of poly-L-lactic acid. The kit of the present disclosure comprises a catabolic filling thread which can be composed of poly-L-lactic acid, is absorbable, has no residue, and is metabolized into lactic acid in the human body. Such a configuration makes the catabolic filling thread itself not only play a role in filling and tightening when filling surgery is performed using the catabolic filling thread of the present disclosure, but also the lactic acid after its metabolism can still stimulate fibroblasts in the skin and subcutaneous tissue to reconstruct the collagen framework in the human body by using fibroblasts.
Owner:KANG SIRONGYI (BEIJING) TECHNOLOGY DEVELOPMENT CO LTD

Cells for burn treatment and burn treatment method

PendingUS20260183340A1Burn treatmentSevere burn
It is an object of the present invention to effectively promote growth of granulation tissue at a dermal defect or a subcutaneous tissue defect caused by a severe burn. To achieve this object, burn treatment cells for use in treatment of burns are composed of placenta-derived cells of an animal and promote healing.
Owner:UNIVERSITY OF TOYAMA +1

Multimodal dynamic haptic encryption method, haptic encryption skin, system and applications

ActiveCN116049852BGranular layerBi modal
The application provides a multi-modal dynamic tactile encryption method, a tactile encryption skin, a system and an application, which comprises the following steps: a dynamic tactile force acts on a tactile encryption epidermis, image data of an initial state of the tactile encryption epidermis and an image data generated in a dynamic tactile action process are collected through a tactile encryption subcutaneous tissue; based on the image data, a position cell tensor, a velocity tensor and a depth tensor generated before and after the encryption epidermis granular layer is subjected to a tactile stimulation are obtained; based on the position cell tensor, the velocity tensor and the depth tensor, a double-modal dynamic tactile feature or a multi-modal dynamic tactile feature based on a dynamic force-velocity-depth coupling is constructed; and the double-modal dynamic tactile feature or the multi-modal dynamic tactile feature is subjected to multi-level standard encryption based on a self-defined initial key to obtain a final dynamic multi-modal tactile process encryption result. The application has high specificity, which includes spatial and temporal features; the encryption process is dynamic, contains the whole process of biological tactile action, and has high reliability.
Owner:SHANGHAI JIAOTONG UNIV

ULTRASOUND EMITTER DEVICE FOR APPLYING SELECTIVE TREATMENTS ON ADIPOSE TISSUE IN BODY REMODELING / REJUVENATION PROCESSES

Ultrasound emitting device for applying selective treatments to hypodermic tissue (adipose and connective tissue) in rejuvenation and / or body contouring processes, comprising an electrical pulse generator, an ultrasonic transducer (3), an electronic control unit (6) equipped with specific software that controls the frequency, voltage, and duty cycle of the pulse generator, and application means (4) for orienting and directing the acoustic field onto the area to be treated on the patient / user, wherein said transducer emits in each pulse an acoustic field with an energy density not exceeding 0.7W / cm2 and a minimum emission duration of 100ms. Preferably, the transducer emits either at a single frequency or in a frequency sweep, in a frequency range between 185 kHz and 333 kHz, and even more preferably at 244 kHz.
Owner:JOSE MANUEL SAENZ JULIA

Cerebrospinal fluid shunt monitoring system

The embodiment of the invention provides a cerebrospinal fluid shunt monitoring system. The cerebrospinal fluid shunt monitoring system comprises a data acquisition unit and a data processing unit, the data acquisition unit is used for acquiring temperatures of upstream and downstream areas of a cerebrospinal fluid shunt tube, and the data transmission component is used for transmitting the temperatures acquired by the temperature detection component to the data processing unit; and the data processing unit is used for processing the temperature acquired by the data acquisition unit so as to determine the flow of cerebrospinal fluid. According to the cerebrospinal fluid shunt monitoring system disclosed by the embodiment of the invention, the quantitative precision can be improved, and the monitoring lower limit reaches 0.01 ml / min; meanwhile, the depth adaptability is achieved, measurement of the subcutaneous tissue thickness of 1-6 mm is supported, and the false detection rate is reduced to tilt; 5%.
Owner:TAIZHOU QIANLIN TECHNOLOGY DEVELOPMENT CO LTD

Knitted device for treating skin and subcutaneous conditions comprising a plurality of protrusions

A knitted device for treating skin and subcutaneous conditions comprising a plurality of protrusions. The knitted device for treating skin and subcutaneous conditions comprises a plurality of protrusions (4) connected to each other by a web (2), said web (2) and said protrusions (4) being knitted from at least two knitting yarns (12, 14) and one weft yarn (16), the two knitting yarns (12, 14) being knitted together to form the web (2), the weft yarn (16) being deposited within said web (2). The knitting yarns (12, 14) are knitted separately and separated from each other to form each protrusion (4), the weft yarn (16) being deposited within each protrusion (4) so ​​as to pad each protrusion (4). Figure for the abstract: 2
Owner:THUASNE SA

Measurement of Tissue Properties Using Pressure Pattern

A method of measuring tissue properties using a fluid line in fluid communication with a subcutaneous tissue includes applying a pressure profile or flow profile to the subcutaneous tissue via the fluid line, with the fluid line isolated from atmospheric pressure, measuring a pressure value or flow rate value over time in response to the applied pressure profile or applied flow profile, and calculating, using at least one processor, at least one of the following: time constant of pressure decay; fluidic resistance of tissue; permeability of tissue; mechanical compliance of tissue; osmotic pressure of interstitial fluid of tissue; capillary pressure in subcutaneous tissue; and ionic strength of interstitial fluid.
Owner:BECTON DICKINSON & CO

Analyte monitoring system

PCT designated stageWO2026137914A1AnalyteMonitoring system
Provided is an analyte monitoring system, which comprises a medical instrument, a piercing member, an applicator, and a cap. The medical instrument comprises an application portion and a sensor secured by the application portion and capable of being at least partially positioned subcutaneously. The piercing member is configured to carry at least part of the sensor into the subcutaneous tissue. The applicator is configured to move the piercing member. The cap is coupled with the applicator and provided with a sealed space to receive at least part of the sensor. Thus, the analyte monitoring system can be provided to a user in an integrated architecture for ease of use by the user.
Owner:SHENZHEN SISENSING TECH CO LTD

Fur opening device for animal subcutaneous tissue sampling

The utility model relates to the technical field of tissue sampling, in particular to a fur opening device for animal subcutaneous tissue sampling. The distraction device comprises a first distraction rod, and a second distraction rod is rotationally arranged in the middle of the surface of the first distraction rod; threaded holes are formed in the surfaces of the first distraction rod and the second distraction rod, positioning mechanisms are arranged in the threaded holes in a threaded mode, and connecting rods are fixedly arranged at the ends, away from the positioning mechanisms, of the first distraction rod and the second distraction rod. According to the fur opening device for animal subcutaneous tissue sampling, by arranging the opening mechanisms, a first opening rod and a second opening rod are separated to open animal fur, at the moment, the two sets of opening mechanisms are arranged on the inner side of the animal fur, a fixing frame is arranged on the outer side of the animal fur, and an inner buckling plate is matched with the fixing frame to open the animal fur; the effect of opening animal fur is achieved, personnel can sample subcutaneous tissue conveniently, and the situation that animal fur is attached to the subcutaneous tissue and influences sampling is reduced.
Owner:NINGXIA ACAD OF AGRI & FORESTRY SCI INST OF ANIMAL SCI (NINGXIA GRASS LIVESTOCK ENG TECH RES CENT)

Implanting device for intervening micro biosensor into subcutaneous tissue

The utility model relates to an implantation device for intervening a micro biosensor into subcutaneous tissue, which comprises a fixed seat and a driving unit, and the driving unit is slidably mounted in the fixed seat and can move relative to the fixed seat along a first direction. The fixing base is provided with a first guide part extending in the first direction, and the driving unit comprises a second guide part extending in the first direction and a second limiting part capable of elastically abutting against the inner wall of the fixing base. And in the movement process of the driving unit relative to the fixed seat, the first guide part is matched with the second guide part, so that the relative movement between the fixed seat and the driving unit can be guided. Meanwhile, in the process that the driving unit moves relative to the fixing base, the second limiting part can elastically abut against the inner wall of the fixing base, and therefore the guiding effect on the movement of the driving unit relative to the fixing base is achieved. Through the design, the possibility that the driving unit shakes in the implanting process can be reduced, the movement stability is improved, and the pain feeling is reduced.
Owner:JIANGSU YUWELL POCT BIOLOGICAL TECH CO LTD +2

Microneedle equipment for subcutaneous tissue interstitial fluid extraction and sampling method

The invention relates to a microneedle device for subcutaneous tissue interstitial fluid extraction and a sampling method, and belongs to the technical field of tissue interstitial fluid extraction.The microneedle device comprises a fixator body, the fixator body comprises an upper fixator and a lower fixator, the two sides of the upper fixator are connected with the two sides of the lower fixator through elastic pieces, and an array channel is formed in the upper fixator; the pressure detection head comprises a pressure detection shell and a sheet-shaped dynamometer probe, a hollow column assembly matched with the array channel is arranged at the bottom of the pressure detection shell, the hollow column assembly comprises a plurality of hollow columns, columns are arranged in the hollow columns in a matched mode, and a containing groove is formed in the pressure detection shell; the microneedle array structure comprises a microneedle structure shell, a capillary tube and a microneedle, a tube body matched with the array channel is arranged at the bottom of the microneedle structure shell, a mounting hole is formed in the tube body, the capillary tube is arranged in the mounting hole, the microneedle is arranged at the bottom of the tube body, and the microneedle is communicated with the capillary tube.
Owner:ZAISHENGHUA (HANGZHOU) BIOTECHNOLOGY CO LTD

Measurement method, system, and related apparatus

A measurement method, a system, and a related apparatus, where the method is applied to a first electronic device, the first electronic device includes a first electrode group and a second electrode group, and a distance between the first electrode group and the second electrode group is greater than a first distance. When the first electrode group and the second electrode group are implanted into a subcutaneous tissue, a first physiological parameter is determined by using the first electrode group; and an electrocardiography signal is determined by using the first electrode group and the second electrode group.
Owner:HUAWEI TECH CO LTD

Biosensors for placement at non-predetermined skin depths - Patent Application 20070122997

A wearable device for continuous monitoring of at least one analyte is provided. The device includes a plurality of aptamer sensors for a particular analyte and means for determining at least one position measurement. The sensors are positionable at distinct locations with respect to depth within a user's skin. The position measurement has distinct measurement responses between at least two skin tissues, such as the epidermis, dermis, and subcutaneous tissue. At least one of the sensors is positionable at a distinct tissue location.
Owner:UNIVERSITY OF CINCINNATI

Injection device for lifting whole face in medical beauty and microsurgery

The utility model belongs to the technical field of medical beauty, and particularly relates to an injection device for lifting the whole face of a medical beauty minice.The injection device for lifting the whole face of the medical beauty minice.The injection device comprises a handle, a waterproof touch switch is fixedly connected to the left side of the handle, and a waterproof battery box is fixedly connected to the inner wall of the handle; a rectangular box body is fixedly connected to the upper surface of the handle, a U-shaped plate is attached to the inner wall of the rectangular box body, and moving mechanisms are fixedly connected to the left side of the inner wall of the U-shaped plate and the inner wall of the rectangular box body. According to the injection device for lifting the whole face of the medical beauty and microsurgery, through cooperation of a C-shaped elastic piece, a positioning block and a connecting plate, an injector can be fixed in a round hole of a left baffle, meanwhile, when a doctor presses a waterproof touch switch on a handle, a needle cylinder on the injector can automatically move rightwards at a constant speed through a moving mechanism, and therefore the whole face of the doctor can be lifted. Therefore, the injection device can uniformly inject fat cells into subcutaneous tissues.
Owner:TONGYANHUI (HANGZHOU) LIFE TECH CO LTD

Intelligent orthosis adaptive pressure control method based on subcutaneous pressure prediction model

The application relates to an intelligent brace adaptive pressure control method and device based on a subcutaneous pressure prediction model, wherein the method comprises the following steps: collecting surface pressure distribution data between a brace and a preset key area of skin in real time; extracting a pressure peak value, a pressure gradient, a pressure duration and a pressure change rate, and fusing the collected physiological parameters of a user to construct a multi-modal feature vector; inputting the multi-modal feature vector into a pre-trained subcutaneous pressure prediction model to predict a subcutaneous pressure experience value of the user; and adjusting the inflation amount of an air bag inside the body of the intelligent brace if the subcutaneous pressure experience value exceeds a preset safety pressure threshold. The application can predict the subcutaneous pressure experience value by collecting surface pressure data in real time and combining physiological parameters, can give an early warning before actual subcutaneous tissue damage occurs, and can cope with pressure changes caused by user activities and posture changes by dynamically adjusting the inflation amount of the air bag.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV

Acupuncture auxiliary device

The invention relates to the field of acupuncture assistance and discloses an acupuncture assisting device which comprises a handle, a needle body is arranged on the lower surface of the handle, an acupoint detecting pen is arranged at the front end of the needle body, anti-falling rings are arranged at the upper end and the lower end of the outer side of the handle, an anti-skid adhesive tape is wound on the outer side of the handle, and a mounting base is inserted into the lower side of the handle. The needle body is inserted into the lower end of the mounting seat, and the mounting seat is formed by filling solid cotton. By arranging the anti-falling ring and the anti-skid adhesive tape, the hand holding friction force is increased, an operator can stably control the direction and the force exerting rhythm of the handle in the operation process, and therefore the safety, accuracy and comfort of acupuncture operation are improved, by arranging the hollow bin and the hole, local vibration and sound waves are generated in the needle flying process, and the acupuncture effect is improved. The vibration is conducted to the periphery through the skin and subcutaneous tissue and diffused along a meridian system to stimulate related nerve endings and meridian qi and blood, so that channel qi conduction is stimulated, and local qi and blood circulation and function regulation are promoted.
Owner:李洪廷

Rosa roxburghii tratt exosome microneedle patch for promoting skin wound healing and preparation method

The invention belongs to the technical field of biological materials, and particularly relates to a rosa roxburghii tratt exosome microneedle patch for promoting skin wound healing and a preparation method of the rosa roxburghii tratt exosome microneedle patch. The roxburgh rose exosome microneedle patch for promoting skin wound healing comprises a patch base body and a microneedle array which are integrally formed, the microneedle array is distributed on the surface of the patch base body, and the patch base body and the microneedle array are made of degradable materials doped with roxburgh rose exosomes; after penetrating through a skin barrier, constructing a roxburgh rose exosome delivery channel and degrading, the roxburgh rose exosome can be uniformly released to a skin wound to accelerate migration of human immortalized keratinocytes, fibroblasts, human umbilical vein endothelium and other cells so as to promote repair and healing of skin tissues such as epidermis, dermis and subcutaneous tissues; according to the application, the application range of the roxburgh rose exosome is expanded, the roxburgh rose exosome is effectively utilized, and the technical problems that the efficacy of the roxburgh rose exosome is lack of research and the roxburgh rose exosome is difficult to effectively apply at present are solved.
Owner:GUANGZHOU WANGLAOJI MAJOR HEALTH IND CO LTD

Acupuncture needle

The invention relates to an acupuncture needle (1) comprising a needle body (2), wherein the needle body (2) has a penetrating region (3), wherein, during use of the acupuncture needle (1), the penetrating region (3) penetrates into the body and comes into direct contact with the subcutaneous tissue (4). The aim of the invention is to provide an acupuncture needle having enhanced therapeutic properties. This aim is achieved in that the acupuncture needle (1) comprises at least one first material (5) and at least one second material (7), wherein the first material (5) and the second material (7) are arranged, at least in certain regions, in the penetrating region (3) such that the first material (5) and the second material (7) come into direct contact with the subcutaneous tissue during use, and wherein the first material (5) and the second material (7), during use, form a galvanic element together with the subcutaneous tissue.
Owner:ZSCHECH NORMAN