42 results about "Intestinal structure" patented technology

The invention provides a functional feed additive for relieving oxidative damage to intestinal tracts of piglets as well as a preparation method and application of the functional feed additive. The functional feed additive is prepared from the following components in parts by weight: 30 to 50 parts of plant extract, 0.5 to 2 parts of operculate cleistocalyx flower polyphenol-mesoporous silicon dioxide nanoparticles, 0.05 to 1 part of vitexin and 1 to 3 parts of sugarcane polyphenol. The product provided by the invention can relieve intestinal structure damage caused by oxidative stress of piglets and protect normal structures and functions of intestinal tracts; inflammatory factors are reduced, inflammatory response is improved, and intestinal health is maintained; the piglet diarrhea is reduced, and the production performance of piglets is improved.

The invention relates to a fermented traditional Chinese medicine composition for preventing and treating piglet viral diarrhea as well as a preparation method and application thereof, and relates to the technical field of livestock breeding. The feed is prepared by taking traditional Chinese medicine components as basic raw materials and adding probiotics for fermentation, and the traditional Chinese medicine components comprise the following raw materials in parts by weight: 0.5-1.5 parts of cardamine violifolia dry powder, 5-15 parts of Chinese pulsatilla root, 10-20 parts of coptis chinensis, 10-20 parts of golden cypress, 10-20 parts of ash bark, 4-8 parts of turmeric, 6-10 parts of pumpkin seeds and 4-8 parts of a ginkgo leaf extract feed additive. Through cooperation of multiple components, the immunity and antioxidant functions of the body are enhanced, the structural integrity of the intestinal tract is maintained, piglet diarrhea caused by PEDV infection is effectively relieved, and growth and development of the piglet are promoted; local specialty crops are selected as medicines, and theoretical basis and practical reference are provided for deep processing of local genuine medicinal materials and PED prevention and control.

The invention discloses application of an aromatic hydrocarbon receptor stimulant in preparation of a medicine for treating diarrhea of weaned piglets and / or inhibiting inflammation, and belongs to the field of biological medicine. According to the present invention, with the PAS-B structural domain of the AHR as the target, the virtual screening technology, the target verification test and the weaned piglet diarrhea pharmacodynamic evaluation test are performed to determine the arctigenin as the AHR strong agonist and the anti-inflammatory drug, and the arctigenin has the good treatment effect on the weaned piglet diarrhea. Experimental results show that 10 mg / kg of arctigenin can significantly relieve diarrhea and hemafecia symptoms of weaned piglets, reduce the content of inflammatory factors in serum and intestinal tissues and improve the intestinal structure of weaned piglets, has no significant cytotoxicity, hepatorenal toxicity and intestinal epithelial cell growth inhibition effect, and can be used for preparing a feed additive for weaned piglets. The compound can be used for preparing medicines for treating diarrhea of weaned piglets. The invention provides a new raw material medicine for treating diarrhea of weaned piglets, and has great economic value and wide application prospect.

The invention provides application of D-mannose in preparation of a product for improving intestinal mucosa immunity and / or intestinal flora homeostasis of weaned piglets, and particularly belongs to the technical field of weaned piglet breeding. The invention provides application of D-mannose in preparation of a product for improving intestinal mucosal immunity and / or intestinal flora homeostasis of weaned piglets. The D-mannose is derived from a natural plant, can stably and efficiently improve intestinal mucosa immunity and intestinal flora homeostasis of the weaned piglets, relieves diarrhea, and improves the growth performance of the weaned piglets at the same time. Specifically, D-mannose can improve the growth performance of weaned piglets, reduce the diarrhea rate, improve the intestinal structure, enhance the chemical barrier function of the intestinal tract, reduce the abundance of harmful bacteria in the intestinal tract and increase the content of short-chain fatty acid producing bacteria.

The application relates to application of iron-nitrogen doped graphene in preparation of anti-radioactive enteritis drugs and belongs to the technical field of biological medicines. ZIF-8 powder, 1,10-phenanthroline powder, iron (II) acetate powder and a grinding medium are placed in a closed container to perform mechanical ball milling treatment to obtain a mixed powder; under the protection of inert gas, the mixed powder is placed in a preheated tube furnace to perform pyrolysis treatment, and is cooled to room temperature to obtain iron-nitrogen doped graphene. The iron-nitrogen doped graphene has NADH oxidase-like activity, can directly catalyze the conversion of NADH into NAD + , can rapidly supplement NAD + depletion caused by radiation, can enhance PARP-dependent DNA damage repair, can reduce the generation of active oxygen (ROS), can reduce intestinal cell death and can protect the integrity of intestinal structure, and can realize efficient protection of radioactive enteritis. Moreover, the problem of low-efficiency biosynthesis of NAD + supplementation in existing radioactive intestinal injury protection technologies is solved.

This invention relates to the field of intelligent medical technology, and more particularly to a method for early warning of intestinal fibrosis in Crohn's disease based on a large model. The method includes: acquiring intestinal MRI image sequences of Crohn's disease patients; inputting the intestinal MRI image sequences into a pre-trained large model for intestinal structure analysis to locate the initial intestinal fibrosis region; determining whether the degree of intestinal luminal stenosis in Crohn's disease patients meets the standard based on the intestinal stenosis progression index, and adjusting the feature contrast threshold of the large model based on the difference; determining whether the acute inflammation masking effect of Crohn's disease patients is adequate based on intestinal wall edema characterization parameters, and adjusting the T2-weighted imaging modal weights of the large model based on the relative difference; and determining whether the patency of the fibrotic permeation channel in Crohn's disease patients is adequate based on the fibrotic permeation resistivity, and adjusting the boundary loss weights of the large model based on the ratio. This invention improves the accuracy of early warning of intestinal fibrosis in Crohn's disease.

The invention discloses application of retinaldehyde dehydrogenase activating peptides derived from three euphausia superba in prevention or treatment of radiotherapy intestinal side reactions, and belongs to the technical field of bioactive peptides. The euphausia superba-derived retinaldehyde dehydrogenase activating peptides have three kinds of amino acid sequences, and the amino acid sequences of the retinaldehyde dehydrogenase activating peptides are respectively shown as SEQ ID NO.1-3. The euphausia superba-derived retinaldehyde dehydrogenase activating peptide is applied to prevention or treatment of radiotherapy intestinal side reactions. According to the invention, three potential retinaldehyde dehydrogenase activated peptides are identified from the antarctic krill protein peptide sequence by using high-resolution mass spectrometry, and the effect of the retinaldehyde dehydrogenase activated peptides on preventing or treating radiotherapy intestinal side reactions is verified by using animal experiments. Results show that three small molecule peptides can improve weight loss and intestinal structure damage caused by radiation, thereby repairing intestinal mucosal barriers and improving side effects of radiotherapy intestinal tracts.

The present invention relates to a sanguisorba officinalis polysaccharide, its preparation method and uses. In the sanguisorba officinalis polysaccharide of the present invention, by weight percentage, the neutral sugar content is 79% - 85%, the uronic acid content is 13% - 19%, and the protein content is 1% - 4%. The composition of the polysaccharide includes mannose, rhamnose, galacturonic acid, galactose, xylose and arabinose. In vitro and in vivo experiments have proved that the sanguisorba officinalis polysaccharide can significantly inhibit the expression of inflammation-related factors in the enteritis cell model and relieve the symptoms of dextran sulfate sodium-induced acute colitis in mice, including the weight loss of mice, the increase of spleen weight index, the reduction of colon length and the intestinal structure damage. And it has no effect on the growth viability of normal intestinal epithelial cells in vitro and has no toxic effect on the important organs of mice in vivo, with high safety. Therefore, the polysaccharide has the potential to treat gastrointestinal inflammatory diseases and is expected to become a candidate carbohydrate drug for treating gastrointestinal inflammatory diseases.

The invention provides a lysozyme-based quercetin colon-targeted nanoparticle as well as a preparation method and application of the lysozyme-based quercetin colon-targeted nanoparticle. According to the invention, a quercetin-Fe < 2 + > metal polyphenol network (MPN) nano core is constructed by a solvent exchange method, and then the quercetin-Fe < 2 + > metal polyphenol network (MPN) nano core, positively charged egg white lysozyme and negatively charged pectin are subjected to electrostatic self-assembly in sequence to form the nano particle with a triple coating structure. The encapsulation rate of quercetin in the nano-particles ranges from 77% to 98%, the drug loading rate ranges from 13% to 32.2%, and the nano-particles have excellent gastrointestinal stability and colon targeting. High-fat model animal experiment results show that the nanoparticles have good lipid-lowering effect and oxidation resistance, and can protect intestinal structures and functions. The problems of poor stability and insufficient targeting in oral delivery of quercetin are effectively solved, and a green and efficient solution is provided for colon targeting delivery of polyphenol functional factors.

The invention provides application of lactobacillus helveticus AFY07 in preparation of intestinal protection drugs, food or health care products, and relates to the technical field of microorganisms. The lactobacillus helveticus AFY07 disclosed by the invention is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.30983. Research finds that the lactobacillus helveticus AFY07 can enhance the intestinal function, so that the intestinal structure returns to normal, the intestinal structure is protected, and the intestinal permeability is reduced.

The invention discloses polygalacturonic acid (PGA) and application of a neohesperidin dihydrochalcone (NHDC) or neohesperidin (NH) embedded compound of the polygalacturonic acid (PGA) in preparation of anti-allergic food or drugs. The PGA has good biocompatibility and immune regulation and intestinal barrier repair functions. Experiments show that the PGA can significantly reduce IgE-mediated food anaphylaxis, alleviate allergic symptoms and improve intestinal structures. PGA is adopted as a carrier, and the PGA and NHDC / NH form non-covalent binding through intermolecular force to prepare the PGA-NHDC / PGA-NH compound, so that the solubility and the stability of the NHDC / NH are improved, and a synergistic anti-allergic effect is also generated. The PGA-NHDC / PGA-NH compound has the advantages of small molecular weight, fast absorption and non-immunogenicity, and can release NHDC / NH in colon in a targeted manner. On the basis, the invention further provides the application of the PGA-NHDC / PGA-NH compound in preparation of the orange juice, the obtained juice system is in a stable suspension state, has no precipitation layering phenomenon, has targeted synergistic antianaphylaxis and high storage stability, and remarkably improves the functionality and the storage stability of the juice.

The invention relates to a probiotic composition and application thereof, and belongs to the technical field of compositions. Comprising Ackerman muciniphila ATCC BAA-835 and Bifidobacterium animalis subsp. Lactis BB-12, wherein the CFU (colony forming unit) ratio of the Ackerman muciniphila ATCC BAA-835 to the Bifidobacterium animalis subsp. Lactis BB-12 is 1 The two strains have a synergistic effect, and the prepared probiotic composition can synergistically relieve the phenomena of weight loss, colon shortening, intestinal structure and intestinal barrier injury, proinflammatory factor increase, anti-inflammatory factor reduction, intestinal flora and histidine metabolism disorder and the like of dextran sodium sulfate induced mouse ulcerative colitis. Therefore, the effect of preventing and relieving the severity of the inflammatory bowel disease is achieved.

The invention relates to the technical field of feed, in particular to application of inulin in improving the laying rate of laying hens and feed efficiency. The laying rate and the feed conversion efficiency are remarkably improved, the laying period is prolonged, meanwhile, the slaughter rate is improved, and the breeding cost is reduced; the eggshell color and structure are adjusted, the eggshell thickness and strength are improved, the egg yolk nutrition index is synchronously improved, and the market competitiveness is enhanced; the serum hormone level is adjusted, the immune response and antioxidant capacity are enhanced, oxidative stress injury is reduced, and the health of chicken flocks is guaranteed; skeletal development and mineral deposition are promoted, serum uric acid and triglyceride levels are adjusted, and metabolic diseases are prevented; the intestinal structure is optimized, the yield of short-chain fatty acid is increased, the content of unsaturated fatty acid in egg yolk is increased, and the flavor and nutritional value of the product are improved; the antibiotic dependence is reduced through a natural substitution mechanism, the trend of green breeding and food safety is met, and the sustainable development of the industry is promoted.

The invention discloses a method for detecting ovalbumin through an electrochemical bionic small intestine micro-fluidic chip sensor and application, and belongs to the technical field of food safety detection. A micro-intestinal chip is designed by simulating the structure of the small intestine of a human body, an anti-IL-6 antibody is integrated on a screen-printed electrode to serve as a specific recognition element, a sensor capable of being used for specifically recognizing cell secretion IL-6 is constructed, and effective and indirect measurement of OVA is achieved. An OVA standard substance is used for testing the bionic small intestine sensor, a good linear relation exists between the resistance value detected by an electrochemical means and the OVA concentration, the linear detection range is 0.2 pg / mL to 4 pg / mL, the detection limit is 0.161 pg / mL, and it is proved that the bionic small intestine sensing interface is feasible and the sensor can conduct quantitative sensitive detection on the allergen protein.

The invention provides an application of yolk immunoglobulin in preparation of a medicine for preventing and treating digestive tract inflammatory diseases, and belongs to the technical field of biological medicines. The egg yolk immunoglobulin is used for preventing and treating inflammatory diseases of digestive tracts, can relieve inflammatory response of the digestive tracts, inhibit disease progression, relieve hemafecia, diarrhea and tissue edema and hyperemia, and can also regulate the immune function of the intestinal tracts, enhance the barrier effect of intestinal mucosa, promote repair of damaged intestinal mucosa, improve the environment in the intestinal tracts from the source and improve the immunity of the intestinal tracts. The intestinal structure is complete, and the phenomenon of sparse villus in the intestinal tract is avoided. Moreover, the egg yolk immunoglobulin is derived from eggs, belongs to a natural bioactive substance, and compared with a chemical synthesis medicine, the egg yolk immunoglobulin is mild in component, does not easily cause strong rejection reaction of an organism, greatly reduces the occurrence probability of allergy and other adverse reactions, is also very friendly to patients with weak gastrointestinal functions, and provides a new thought for prevention and treatment of digestive tract inflammation.

The utility model discloses a novel power distribution instrument, which comprises a shell and a circuit board, the shell comprises a bottom shell and a panel, the panel is provided with a code identification area, and the circuit board is provided with a Bluetooth module. The power distribution instrument has the beneficial effects that after the code identification areas are arranged, the external equipment can quickly realize the connection between the power distribution instrument and the external equipment through the Bluetooth module by scanning the corresponding code identification areas. Therefore, equipment maintenance, equipment inspection, equipment debugging and the like can be conveniently carried out. Meanwhile, the terminal and the mutual inductor structure are integrated on the circuit board in a combined mode, the overall thickness of the power distribution instrument is greatly reduced, the requirement for the size of the power distribution instrument is reduced, and the overall thickness and cost are greatly reduced.

The invention discloses application of sodium butyrate in improving the yield of royal jelly, and belongs to the technical field of biology and agriculture. In the royal jelly production process, a production group is fed with sodium butyrate with a certain concentration to promote intestinal structure development and intestinal barrier repair of the production group, meanwhile, the immunity of the organism is improved, the feed intake of worker bees is increased, and the feed digestibility is improved, so that the royal jelly yield is improved, and the royal jelly yield of a single queen cell can reach 105mg 48 hours after bees are transplanted. The method provided by the invention improves the yield of the royal jelly of the apis cerana, and can also be popularized to western bees and other bee species.

The invention relates to the technical field of fungus prevention and control agents, and discloses a fungus prevention and control agent for Mongolia desmodium and a manufacturing method thereof.The fungus prevention and control agent for Mongolia desmodium is obtained after beauveria bassiana, sophocarpidine and auxiliaries are added into a stirrer to be stirred, and then the fungus prevention and control agent for Mongolia desmodium is obtained; beauveria bassiana can infect adults of Mongolia and colonize the adults of Mongolia in the early stage of infection, hyphae start to rapidly grow by means of nutrient substances and water on the body walls of the adults, germinate and invade the interiors of the adults, and the structures of the adults are decomposed; in the later stage of infection, hyphae invade muscular tissues of insect bodies, the insect bodies move slowly, the hyphae obtain nutrient substances in intestinal structures of the insects for mass propagation, and meanwhile, the insect bodies are difficult to obtain sufficient nutrient substances and die due to physiological metabolism disorder; the matrine and the beauveria bassiana have good compatibility, and can cooperate with the beauveria bassiana; in addition, the silver-containing titanium dioxide, the modified cardanol and the nano TiO2 have a relatively good antifungal effect.

The present invention addresses the problem of providing: a feeder cell for maintaining or proliferating a cell, which is considered to be difficult to maintain and proliferate by two-dimensional culture, by two-dimensional culture; and a method for producing the feeder cell. A feeder cell is produced by proliferating and isolating fibroblast-like cells derived from an intestinal structure comprising endoderm-derived cells and mesoderm-derived cells, said intestinal structure being produced from pluripotent stem cells.

A gastrointestinal implant adapted to be implanted in a gastrointestinal structure such as a duodenum, a jejunum, and / or an ileum comprises a plurality of adjacent layers bonded to one another. One of more of the layers comprises at least one of a selected pore size and interpore distance, and at least one medicament is coupled to at least one medial surface of one or more layers to achieve one or more treatment goals selected from minimizing or alleviating trauma associated with implantation of the gastrointestinal sleeve, preventing or treating infection, treating eating disorders or conditions of the patient, treating one or more gastrointestinal tract structures exterior to or distal to at least a portion of the sleeve, or treating the patient's microbiome.

The invention provides a functional feed additive for relieving clostridial enteritis of meat poultry as well as a preparation method and application of the functional feed additive. The functional feed additive is prepared from the following components in parts by weight: 30 to 50 parts of plant extract, 0.5 to 2 parts of monatomic microelement-mesoporous silicon dioxide nanoparticles, 0.1 to 2 parts of momordica saponin and 1 to 3 parts of sarcandra glabra polysaccharide. The product provided by the invention can relieve chicken intestinal structure damage caused by clostridium perfringens and protect normal structures and functions of intestinal tracts; inflammatory factors in jejunum are reduced, inflammatory response is improved, clostridium perfringens colonization is reduced, and the intestinal health level is maintained; furthermore, clostridial enteritis of meat poultry is reduced, and the production performance of broilers is improved.

The utility model discloses an enema device with an auxiliary enema structure, which comprises an enema bag, a scale rope arranged on one side of the enema bag and an infusion tube connected to the bottom of the enema bag, the other end of the infusion tube is connected with an enema tube, and one end of the enema tube close to the infusion tube is provided with a lubricating structure. The end of the movable sleeve is fixed to the fixed sleeve in a screwing mode, a lubricating oil agent blasting bead is arranged on the inner side of the movable sleeve, the lubricating oil agent blasting bead can be manually pressed and extruded to be exploded when the lubricating structure is used, paraffin oil is coated on a pipeline through the movable sleeve, and the pipeline can be lubricated through the paraffin oil. The position close to the insertion end of the enema tube is sleeved with the inflatable air bag, the inflatable air bag can prevent liquid medicine from entering the rectum and flowing out, after the enema tube is inserted into the specified depth, the infusion tube can be fixed to the hip of a patient by tearing off the fixing paste on the outer surface of the fixing sleeve, falling is prevented, and manual handheld fixing is not needed.

The invention belongs to the technical field of natural product extraction and biological medicine preparation, and particularly relates to a jerusalem artichoke extract and application of the jerusalem artichoke extract in resisting inflammation and regulating intestinal flora and metabolites thereof. Tests prove that the jerusalem artichoke extract has the effect of relieving ulcerative colitis. Specifically, the jerusalem artichoke extract can relieve intestinal structure injury, inflammatory cell infiltration and intestinal barrier injury caused by DSS induction, and has the function of relieving ulcerative colitis. Meanwhile, the invention discloses the anti-inflammatory effect of the jerusalem artichoke extract. In addition, the jerusalem artichoke extract also has an effect of regulating intestinal flora. According to the technical scheme, the jerusalem artichoke extract obviously regulates intestinal flora disorder induced by DSS. The jerusalem artichoke extract relieves intestinal flora imbalance of DSS-induced mice, recovers a microbial community structure and regulates metabolites of the DSS-induced mice. The extraction method of the jerusalem artichoke extract is simple and low in cost, has universality and is easy for large-scale production, so that the jerusalem artichoke extract has good practical application value.

The invention relates to the technical field of intelligent medicine, in particular to a Crohn disease intestinal fibrosis condition early warning method based on large model driving, which comprises the following steps: acquiring an intestinal MRI image sequence of a Crohn disease patient; inputting the intestinal MRI image sequence into a pre-trained intestinal structure analysis large model, and positioning the position of an initial intestinal fibrosis region; determining whether the intestinal lumen stenosis degree of the patient with the Crohn disease reaches the standard or not based on the intestinal lumen stenosis progress index, and determining a feature comparison threshold value for adjusting the large model according to the difference value; determining whether the acute inflammation shielding effect of the patient with the Crohn disease is qualified or not based on the intestinal wall edema characterization parameters, and determining and adjusting the T2 weighted imaging modal weight of the large model according to the relative difference; and determining whether the fibrosis seepage channel smoothness of the patient with the Crohn disease is qualified or not based on the fibrosis seepage resistivity, and determining and adjusting the boundary loss weight of the large model according to the ratio. The early warning accuracy of the intestinal fibrosis condition of the Crohn's disease is improved.

The invention relates to the technical field of breeding feed. The invention provides a composition containing astragalus polysaccharide and an acanthopanax senticosus extract, which is characterized in that the mass ratio of the astragalus polysaccharide to the acanthopanax senticosus extract is 10: (1-10), and the composition can be used for preparing feed with the effects of resisting oxidation, relieving inflammation, increasing growth rate, improving intestinal structure and enhancing digestive enzyme activity. The invention also provides a larimichthys crocea juvenile fish feed containing 0.1-0.2% of the composition, and by using the feed combined with the astragalus polysaccharide and the acanthopanax senticosus extract, the growth rate, the survival rate and the stress recovery of the larimichthys crocea juvenile fish are obviously improved; the anti-inflammatory effect is effectively achieved by inhibiting a TLR / MyD88 pathway; the intestinal structure is obviously improved; the digestive enzyme activity is enhanced; the activity of antioxidant enzyme is improved and the concentration of malonaldehyde is reduced, so that the antioxidant defense capability is enhanced.

The invention relates to application of Xpac and Det genes as biomarkers of drosophila melanogaster to nanoparticle combined cadmium pollution, which verifies the regulation effect of XPAC and Det on intestinal tract structure, DNA stability and cell apoptosis under the condition of combined pollution by knocking down the XPAC and Det genes. Results show that DNA damage is aggravated after XPAC knock-down, and Det knock-down causes serious intestinal structure damage and skeleton disintegration, which indicates that the XPAC and Det knock-down have functional differentiation in coping with combined pollution. The gene can be used as a key regulatory factor and a potential biomarker of an environmental pollution toxic reaction, and a theoretical basis is provided for pollution toxicological mechanism research and biological prevention and control strategies.

The invention relates to the technical field of microorganisms, and in particular relates to a plant lactobacillus for preparing a diarrhea postbiotic relieving plant lactobacillus and an application of the plant lactobacillus. According to the present invention, the lactobacillus plantarum is lactobacillus plantarum Mei1101.2, the preservation number is CGMCC No.30331, and the lactobacillus plantarum has characteristics of strong antibacterial activity, high yield of exopolysaccharides, good acid production performance, and good growth performance, and can be used for the production of the exopolysaccharides. According to the present invention, with the application of the phytobacterium plantarum, the diarrhea index and the excrement water content of mice can be reduced, the serum proinflammatory factor content of the mice can be reduced, the anti-inflammatory factor content can be increased, the damage of the duodenum and jejunum intestinal structures and the intestinal mucosal barrier of the mice can be improved, the intestinal flora can be adjusted, and the generation of short-chain fatty acid can be promoted; the animal diarrhea is effectively relieved.

The invention discloses application of cedrol in preparation of a medicine for treating acute ulcerative colitis, and belongs to the technical field of biological medicine. Experiments prove that cedrol can effectively improve DSS-induced colon injury, relieve inflammatory response, improve the intestinal mucosa barrier function, slow down weight loss caused by ulcerative colitis, reduce disease activity indexes, relieve the phenomena of colon shortening and loose stool and protect the structural integrity of colon; the invention provides a theoretical basis for researching and developing medicines for treating ulcerative colitis, and has wide clinical application value.

The present invention belongs to the technical field of bioreactors, and is a spherical segmented feeding intestinal bionic reactor and a control method thereof. The bionic reactor comprises a tank body, a bionic intestinal device, a spherical material container, a feeding device, a discharging device and a stirring device; the feeding device is arranged at the upper end of the tank body, the discharging device is arranged at the lower end of the tank body, the bionic intestinal device and the stirring device are arranged inside the tank body, one end of the bionic intestinal device is connected to the feeding device, and the other end is connected to the discharging device; the present invention designs the specific connection and execution mode of the intestine and the reactor, so that quantitative addition of materials becomes possible, the discharged materials can be conveniently collected and detected, and the scum problem of cellulose materials can be reduced; the intestinal structure cooperates with the spherical material container, which can meet the precise hydraulic retention time of the material and optimize the biochemical reaction efficiency.

The invention discloses application of abelmoschus manihot flower polysaccharide in prevention of intestinal injury caused by ionizing radiation, and belongs to the field of prevention of radioactive intestinal injury. According to the application of the abelmoschus manihot polysaccharide in preparation of the medicine for preventing the intestinal injury caused by the ionizing radiation, the protective effect of AMP on the intestinal injury caused by 14Gy X-ray total abdominal irradiation is found by respectively carrying out ionizing radiation irradiation on mice in an irradiation control group and an irradiation + AMP group, and further experiments find that the ionizing radiation causes apoptosis of intestinal crypt cells, so that the intestinal injury caused by 14Gy X-ray total abdominal irradiation can be prevented. The regeneration capacity of the intestinal structure is destroyed, and the AMP can remarkably inhibit mouse intestinal crypt cell apoptosis induced by ionizing radiation. The invention shows the uniqueness of AMP in the protection of ionizing radiation induced intestinal injury, and has wide application prospects in the medical field.