176 results about "Vomiting" patented technology

The invention relates to the technical field of medical instruments, in particular to emergency clinical emetic equipment which comprises a support, an emetic part arranged on the support and expansion parts symmetrically arranged on the two sides of the emetic part. The retreating assembly is used for driving the support to move so that the expansion pieces and the emetic piece can retreat from the oral cavity of the patient, the support is provided with a first reset piece capable of enabling the emetic piece to be away from the throat and a second reset piece capable of enabling the two expansion pieces to be closed, and the guide rail is provided with a control switch. The vomiting promoting driver drives the vomiting promoting piece to vibrate in the throat of the patient, the vomiting promoting process of the patient is achieved, and when the patient feels strong nausea and is about to have vomiting reaction, the control switch is pressed down in advance; and the emesis promoting piece and the expanding piece quickly restore to original positions under the action of the first resetting piece and the second resetting piece and move out of the oral cavity of the patient through the support, so that the vomiting process is smooth, and the risk that vomit blocks or is inhaled into the airway by mistake is avoided.

The invention provides a nicotine orally disintegrating tablet with a multi-layer composite sustained-release structure and a preparation method of the nicotine orally disintegrating tablet. The nicotine orally disintegrating tablet comprises an inner layer, a middle layer and an outer layer, wherein the middle layer and the outer layer sequentially coat the inner layer from inside to outside; the outer layer comprises nicotine, instant starch and a lubricant; the middle layer comprises nicotine, ethyl cellulose, polyethylene glycol and a flow aid; the inner layer comprises the following components: nicotine nanoparticles coated with chitosan and sodium tripolyphosphate, an oral microenvironment regulator and a filling agent. According to the nicotine orally disintegrating tablet provided by the invention, due to the gradient coating structure design of the inner layer, the middle layer and the outer layer, the multi-stage accurate release of nicotine, namely early-stage quick release, middle-stage stable release and later-stage slow release, is realized, the reactions of dizziness, vomiting and the like caused by excessive release of nicotine are avoided, and the use comfort is improved. Meanwhile, the pH value of the oral cavity is adjusted, micro-ecological balance of the oral cavity is maintained, the content of volatile sulfide in breath is reduced, and breath is refreshed.

The invention relates to the technical field of traditional Chinese medicines, in particular to a hangover-alleviating, liver-protecting and stomach-protecting agent and a preparation method thereof. The alcohol effect dispelling, liver protecting and stomach protecting agent is prepared from the following raw material components in parts by mass: 1-10 parts of peristrophe japonica, 1-10 parts of penthorum chinense pursh, 1-10 parts of flos puerariae, 1-10 parts of radix puerariae, 1-10 parts of lalang grass rhizome, 1-10 parts of hovenia dulcis thunb and 1-5 parts of taurine. The traditional Chinese medicine composition has better hangover-alleviating and liver-protecting effects, obviously shortens the hangover-alleviating and sobering time, is taken before drinking, takes effect faster, has the effects of alleviating hangover, inducing resuscitation, strengthening the spleen and stomach, calming the adverse-rising energy, arresting vomiting and protecting the liver, reduces AST and ALT in human serum, can enhance the activity of ethanol dehydrogenase and acetaldehyde dehydrogenase in the human liver, and promotes ethanol metabolism.

The utility model relates to the technical field of clinical nursing, and discloses a bedridden patient vomit measuring cup which comprises a measuring cup body, scale marks are arranged on one side of the measuring cup body, an L-shaped clamping piece is fixedly connected to the side, away from the scale marks, of the measuring cup body, and a cup cover is connected to one side of a cup opening of the measuring cup body. One side of the cup cover is connected with a rotating assembly, the other side of the rotating assembly is connected with the metering cup body, the side, away from the rotating assembly, of the metering cup body is connected with a clamping assembly, the other side of the clamping assembly is connected with the cup cover, and the outer wall of the metering cup body is fixedly connected with two symmetrically-arranged cup handles. According to the vomiting measuring cup for the bedridden patient, the measuring cup is clamped beside a sickbed used by the patient through the L-shaped clamping plate, when the patient feels vomiting, the patient can vomit into the measuring device only by slightly leaning to one side or deviating the head, the vomiting amount of the patient can be observed in time through the scale marks on the measuring device, and medical staff can conveniently record the illness state of the patient.

This invention provides a novel GABA structure with better efficacy, reduced side effects, and greater safety for clinical use. A This invention relates to receptor agonists, specifically a phenol derivative, its preparation method, and its use in the central nervous system. The phenol derivative provided by this invention offers more and better drug options for inducing or maintaining anesthesia in animals or humans, promoting sedation and hypnosis, and treating and / or preventing anxiety, nausea, vomiting, migraines, seizures, epilepsy, neurodegenerative diseases, and other central nervous system-related disorders.

The utility model relates to the field of anesthesia medical instruments, in particular to an anesthesia postoperative vomiting nursing bag which comprises a bag body, and the bag body is integrally formed by three layers of materials, namely a flow guide layer, a water absorption layer and a waterproof layer from inside to outside. One side of the bag opening of the bag body is upwards provided with a bag opening extending part, and the upper end of the bag opening extending part is provided with a convex arc-shaped neck support; the post-anesthesia vomit nursing bag is fixed to the neck of a patient through the buckle belt assembly, the bag opening extending part and the neck support abut against the gap between the neck and the mouth, and the problems that the vomit bag topples over and falls off, and vomit is scattered on the body of the patient to cause secondary pollution are effectively solved; the bag body is integrally formed by the flow guide layer, the water absorption layer and the waterproof layer, the water absorption layer is made of super absorbent polymer (SAP), vomitus liquid can be absorbed in time, and cleaning difficulty is reduced.

The application belongs to the technical field of emetic, and specifically discloses an emetic device for emergency department, which comprises an emetic trolley, a buffer soft negative pressure production device, a pharyngeal stimulation device and a vomit collection device. The emetic device is capable of realizing individualized and accurate emesis for different patients through double self-adaptive adjustment of height and stimulation frequency, and significantly improves the emetic efficiency and comfort. The innovative integrated air self-purification system can actively eliminate the irritating odor of vomit, and fundamentally improves the diagnosis and treatment environment. The device synchronously solves the four core problems of adaptability, efficiency, hygiene and environmental friendliness in an integrated manner, and provides a revolutionary emetic solution for clinical treatment.

The invention discloses a chemotherapy vomitus collecting device, and relates to the technical field of medical machinery, the chemotherapy vomitus collecting device comprises a collecting box, a fixing frame is fixedly connected in the collecting box, a detachable collecting funnel is arranged in the fixing frame, a sealing bag is arranged at the bottom of the collecting funnel, a hanging device is arranged in the collecting box, and the hanging device is fixedly connected with the fixing frame. And the mounting device is used for manually mounting the opened sealing bag on the mounting device. The whole device takes a collecting box as a main body. A fixing frame is installed in the device to serve as a structural framework, a detachable collecting funnel is arranged on the fixing frame, and a disposable sealing bag is hung below the funnel. The core mounting device is installed in the fixing box and is responsible for unfolding the sealing bag and timely sealing the sealing bag after the vomitus is collected. Meanwhile, a purifying device is integrated on one side of the exterior of the collecting box to eliminate peculiar smell, and the peculiar smell is prevented from being emitted during vomiting.

The invention discloses an intelligent laryngeal mask for the anesthesiology department, relates to the technical field of the anesthesiology department, and aims to provide the intelligent laryngeal mask for the anesthesiology department, which can lead vomiting liquid out of the esophagus and prevent the vomiting liquid from flowing back into the airway when a patient vomits. The first annular air bag is arranged on the ventilation pipe and is aligned with the inflation pipe, a flow guide pipe is arranged below the ventilation pipe, one end of the flow guide pipe is aligned with the esophagus, and the other end of the flow guide pipe extends out of the oral cavity. Meanwhile, the flow guide pipe located below the breather pipe is aligned with the esophagus, when the patient vomits, vomiting liquid enters the flow guide pipe through the esophagus under the pressure effect and then is discharged out of the oral cavity through the flow guide pipe, and the problem that the vomiting liquid extrudes the breather pipe open and flows back into the air inlet channel is solved.

A traditional Chinese medicine composition for alleviating gastrointestinal toxic side effects caused by chemotherapy, the traditional Chinese medicine composition for daily administration is prepared from the following weight ratio of traditional Chinese medicine formula: Taizishen 20-30g, Fuling 10-15g, Fried Baizhu 10-15g, Zhigancao 5-10g, Jiangbanxia 5-10g, Chenpi 5-15g. The formula can effectively alleviate the gastrointestinal toxic side effects caused by chemotherapy, such as nausea, vomiting, diarrhea, poor appetite, etc.

The invention relates to the technical field of medical instruments, in particular to a digestive infection vomiting device which comprises a collecting box and a top cover, the top cover is movably mounted at the top of the collecting box, a collecting groove is formed in the collecting box, a control panel is mounted on the upper surface of the collecting box, and a protection assembly is arranged at an opening of the collecting groove. And an ultraviolet lamp is mounted in the center of the top cover. Through the arrangement of the protection assembly, in the use process, a garbage bag can be conveniently arranged on a positioning rod in a sleeving mode and fixed through a positioning cover, collection is facilitated when a patient vomits, through the cooperative arrangement of a driven wheel, a connecting rod, a small gear and a movable block, the positioning rod is folded towards the center to seal the garbage bag, and the garbage bag can be conveniently collected. The situation that a large amount of peculiar smells, bacteria and viruses fly out to cause environmental pollution is avoided, the probability that other people are infected by the bacteria or the viruses is reduced, and meanwhile after the top cover is closed, ultraviolet rays can disinfect and sterilize the interior of the collecting tank.

The application provides a kind of anti-vomiting infant medicine feeding device, including bottom plate, back plate and back-patting mechanism, back-patting mechanism includes mounting seat, patting plate and driving mechanism. By making the child sit on the bottom plate, back against the patting plate and back plate to maintain sitting position, then start the motor to make the rotating disc rotate, the rotating disc rotates to drive multiple groups of semi-circular conical columns to rotate, multiple groups of semi-circular conical columns rotate to sequentially extrude the ejector rod to make the ejector rod move along the outer surface of the semi-circular conical column, so that the ejector rod drives the patting plate to move away from the rotating disc, at the same time, multiple groups of tension springs are stretched, when the semi-circular conical column rotation cancels the extrusion on the ejector rod, the counterforce of multiple groups of tension springs makes the patting plate move reversely and reset, through multiple groups of semi-circular conical column rotation to sequentially extrude the ejector rod to drive the patting plate to reciprocate, the back of the child can be repeatedly pat, which is convenient for patting the back of the child to help the child to expel the air in the stomach, improve the anti-vomiting effect and improve the practicability of the device.

The utility model relates to the technical field of medical instruments, and discloses a postoperation bedridden patient vomitus collector which comprises a collecting bag, the collecting bag comprises a bag opening and a bag body, a supporting ring is sleeved on the outer side of the joint of the bag opening and the bag body, at least four rotating pieces are arranged on the supporting ring, supporting rods are arranged on the rotating pieces and located on the lower portion of the bag opening, and the bag opening is connected with the bag body. Fixing clamps are arranged at the other ends of the two supporting rods located on the same side, and at least two stickers are arranged on the supporting rods. The supporting rod is of a hollow structure, an elastic rope is arranged on the fixing clamp, and the elastic rope is fixed in the supporting rod. The condition of vomitus can be observed through the transparent collecting bag after vomiting is completed, and sanitation and convenience are achieved; the collecting bag is disposable, convenient to disassemble and discarded after being used, and is low in price and high in economic benefit; even if the head of the patient rotates leftwards and rightwards, the collecting bag can be well attached to the face of the patient, and vomitus is prevented from being splashed out.

The invention discloses lung cancer patient vomiting nursing equipment which comprises a base plate, a supporting plate is fixedly connected to the top end of the base plate, a vomiting basin is fixedly connected to the top end of the supporting plate, and a clamping piece for fixing a vomiting bag in the vomiting basin is arranged on the base plate. The base plate is provided with a discharging part for containing the vomit bag falling from the vomit basin due to gravity, the vomit basin is provided with a sealing part for sealing the vomit bag moving along with the discharging part, and the base plate is provided with a discharging part for discharging the sealed vomit bag; the fixing balls in the clamping pieces abut against the outer side of the vomit basin in a multi-point mode, uniform annular clamping force is formed, it is ensured that the vomit bag is firmly fixed, falling caused by movement of a patient or shaking of equipment is avoided, clamping can be relieved through lever type pressing top plate design and single-hand operation, and the elastic reset function of the first spring is combined, so that the clamping effect is improved. Rapid switching of one-key release or automatic reset is achieved, and nursing efficiency is greatly improved.

The present invention relates to the field of medical auxiliary equipment, and in particular to an emetic device for emergency department nursing, comprising: a shell, a through hole is provided through the center of the shell, and a fixed column is fixedly provided in the through hole; an anti-fouling sleeve is provided in the through hole in the center of the shell; a jaw pressure plate, the jaw pressure plate is symmetrically provided at the upper and lower ends of the shell, and a contact portion is provided at the front end of the jaw pressure plate; a sliding plate, the sliding plate is symmetrically provided up and down inside the shell; a lifting plate, the lifting plate is symmetrically provided up and down inside the fixed column; a stimulation rod, the stimulation rod is slidably provided through the center of the fixed column, and the stimulation rod and the anti-fouling sleeve are provided coaxially; a flushing assembly, the flushing assembly is symmetrically provided on both sides of the shell. The present invention effectively avoids contamination caused by leakage of vomitus, and at the same time, the closed vomiting environment greatly reduces the psychological burden of the patient. The entire stimulation and emetic process is achieved by the patient's autonomous biting action, without the assistance of medical staff, and the patient's psychological burden is relatively light.

The invention relates to the field of medical auxiliary instruments, in particular to an emergency department nursing emetic device which comprises a shell, a through hole is formed in the center of the shell in a penetrating mode, and a fixing column is fixedly arranged in the through hole; the antifouling sleeve is arranged in the through hole in the center of the shell; the jaw pressing plates are symmetrically arranged at the upper end and the lower end of the shell, and contact parts are arranged at the front ends of the jaw pressing plates; the sliding plates are symmetrically arranged in the shell up and down; the lifting plates are symmetrically arranged in the fixing column up and down; the stimulation rod is arranged in the center of the fixing column in a sliding and penetrating mode, and the stimulation rod and the antifouling sleeve are coaxially arranged; the flushing assemblies are symmetrically arranged on the two sides of the interior of the shell. Pollution caused by vomit leakage is effectively avoided, meanwhile, the psychological burden of a patient is greatly reduced through the closed vomiting environment, the whole stimulation emetic process is achieved through the independent occlusion action of the patient, assistance of medical staff is not needed, and the psychological burden of the patient is low.

The present invention belongs to the field of biomedicine, and particularly relates to a detection method for a spleen-strengthening and hangover-relieving mixture. Combining the clinical experience of famous veteran traditional Chinese medicine doctors, the present invention is modified and added on the basis of Gehua Jiedu Decoction, taking into account strengthening the spleen and protecting the liver, promoting digestion and stopping vomiting, clearing heat and resolving dampness, and the spleen-strengthening and hangover-relieving empirical formula is composed as follows: Flos Puerariae, Radix Puerariae, Flos Chrysanthemi, Scutellariae Baicalensis Tablets, Fructus Citri Sarcodactylis, Rhizoma Atractylodis Macrocephalae, Radix Paeoniae Alba, Poria, Caulis Bambusae in Taenia, Cortex Moutan, Fermented Medicated Leaven, Rhizoma Bletillae, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae. The present invention has carried out thin-layer identification, characteristic spectrum analysis, and quantitative analysis of index components on this preparation, and has the remarkable advantages of simple operation and easy popularization and use, and can be applied to the product quality analysis of this mixture.

Neonatal congenital duodenal obstruction is an intestinal lumen obstructive disease caused by abnormal development of the duodenum during fetal period, and it is a relatively common type among neonatal digestive tract obstructions. Its global incidence is approximately 1 / 5000 to 1 / 10000 neonates, and it is more common in Asian populations. The typical clinical manifestations of this disease include vomiting, upper abdominal distension, and delayed passage of meconium after birth. The present invention provides a method for establishing a zebrafish model for simulating duodenal obstruction, and additionally provides a design idea for the target.

The invention relates to the technical field of massage, in particular to an anti-vomiting massage device for chemotherapy nursing, and provides the following scheme aiming at the defect that in the prior art, the neck is inconvenient to massage at the same time, so that the use feeling is poor, the anti-vomiting massage device for chemotherapy nursing comprises a wearing main body, and a first air bag is mounted on the inner wall of the wearing main body; a first air pump is fixedly mounted on the wearing main body, and the output end of the first air pump is fixedly connected with the first air bag; the number of the connecting blocks is two, the two connecting blocks are both fixedly installed at the top of the wearing main body, a shell is fixedly installed on the two connecting blocks, a second air bag is installed on the inner wall of the shell, a second air pump is fixedly installed on the shell, and the output end of the second air pump is fixedly connected with the second air bag. And the massage plate is mounted on the inner wall of the shell, so that the neck can be massaged at the same time, and the use feeling is improved.

The present invention discloses a multifunctional sputum aspirator, which comprises: a ventilation structure for connecting the patient's airway with the outside; an airbag disposed at the front end of the ventilation structure and capable of expanding to cover the opening of the patient's airway; and a sputum aspiration assembly passing through the ventilation structure and the airbag and having a front end that can extend into the patient's airway to discharge the secretions in the airway. The multifunctional sputum aspirator of the present invention has a simple structure, low difficulty in placement and operation, can establish an artificial airway in the patient's oral cavity, has reliable ventilation, small damage to the airway mucosa, high success rate, can efficiently discharge the secretions in the patient's airway, and reduces vomiting and aspiration under the stimulation of sputum aspiration in the patient.

The invention discloses a nursing device special for tumor chemotherapy, and relates to the technical field of chemotherapy nursing instruments, and the nursing device comprises a fixing device used for supporting and protecting parts required by chemotherapy nursing for the oncology department; the moving device is located on one side in the fixing device; the massage assembly is located on one side of the moving device and located in the fixing device. The telescopic rod lifts the rotating rod, the motor drives the rotating rod to rotate, the massage rod is lifted alternately for massage, when vomiting is needed, a patient stands up, the pressure sensing device controls the moving plate to move outwards, the spittoon extends out of the device for vomiting, then the patient lies down, the pressure sensing device controls the moving plate to retract, and the clamping frame moves, so that the spittoon extends out of the device for vomiting. The spittoon can be automatically ejected, vomitus of a patient can be conveniently collected, the aim of massaging the body of the patient can be achieved, and the situation that muscle atrophy is caused due to the fact that blood is not circulated when the patient lies in a bed for a long time is avoided.

The suppression of the gag reflex response, administered through a training device and associated desensitization method(s), without medical intervention, is desirable for many people who suffer from gag reflex response issues. An oral acclimation training device comprise various thickness(es) and length(s) and may have components to prevent swallowing or choking of the device by the user. Further, the device may be part of a kit having multiple training objects with specific attributes (e.g. thickness, depth, shape, finish, texture) that are designed for a specific stage in the training sequence and tailored for the user's inherent gag reflex sensitivity. Training objects are designed to provide optimal stimulus range to cause desensitization but not cause severe gagging or vomiting. The gag suppression stemming from this device is long-term, meaning that it may last for many weeks or months, depending on the individual. This duration may be extended indefinitely by occasional re-training or similar conditioning.

The invention relates to the technical field of vomit collecting equipment, and particularly discloses a general anesthesia postoperative vomit nursing device which comprises a mounting frame. The collecting hopper is detachably arranged at the bottom of the mounting frame, a collecting bag is fixed to the surface of the connecting position of the collecting hopper and the mounting frame, and a containing part of the collecting bag is arranged on the inner side of the collecting hopper; and the sealing assembly is arranged on the mounting frame. Through the arrangement of the sealing assembly, when a patient needs to vomit, the patient firstly turns over the head, presses a soft cushion with the head and drives an inserting rod at the bottom to move downwards, the inserting rod moves downwards to drive two sealing covers which are in sliding connection to rotate downwards, and the whole collecting hopper can be opened by rotating the sealing covers downwards; and after the head of the patient is reset, the patient is reset through the reset spring, and the sealing cover can be sealed and reset again, so that the vomit gas is prevented from overflowing. The problems that an existing vomiting nursing technology is inconvenient to use, pollutes the environment, increases the infection risk and the like are solved.

The utility model discloses a portable vomiting device which comprises an adjusting scarf, a vomiting barrel and a movable assembly, and the adjusting scarf comprises a scarf body, a left connecting belt, a right connecting belt, an adjusting semi-ring and a connecting opening; the vomiting barrel comprises a vomiting barrel cover, an upper barrel body and a lower barrel body, the section of an opening of the vomiting barrel is trapezoidal, and a sealing cover is detachably connected to an outlet in the bottom of the lower barrel body; a filter screen is arranged between the upper barrel body and the lower barrel body; an annular hollow groove and a sampling barrel are arranged in the lower barrel body; the movable assembly comprises fixing pieces, a movable shaft and a connecting piece, the fixing pieces are fixed to the upper portion of the short edge face of the vomiting barrel, and the movable shaft sequentially penetrates through the through hole of one fixing piece, the movable hole of the connecting piece and the through hole of the other fixing piece to fix the connecting piece between the two fixing pieces; the other end of the connecting piece penetrates through the connecting opening to be connected with the neckerchief body. The vomitus collecting device is convenient for a patient to carry, so that the patient is not limited by places, and the vomitus is collected when the patient suddenly vomits, so that the vomitus is prevented from polluting public places.

The invention discloses a double-agonist polypeptide compound and medical application thereof, and belongs to the field of polypeptide medicine, the amino acid sequence of the GIP-R and GLP-1R double-agonist polypeptide compound is Y-Z-EGTFTSDSI-X2-LDKI-A-Q-Bn-X4-X5-VQWLI-X6-GGPSSG-A-PPPS, and the amino acid at the C terminal is amidated. The GIP-R and GLP-1R dual-excitation polypeptide compound disclosed by the invention has a more remarkable dual-excitation effect on a human glucose-dependent insulinotropic polypeptide (GIP) and a human glucagon-like peptide-1 (GLP-1) receptor, not only has the effects of reducing blood glucose and reducing weight, but also has a longer half-life period and higher bioavailability; adverse reactions such as nausea and vomiting caused by long-term use of existing medicines can be avoided, and the traditional Chinese medicine composition can be used as an effective raw material for preparing medicines for treating or preventing diabetes or weight-reducing medicines.

The present application provides a propofol analogue, a preparation method thereof and application thereof in non-narcotic field. The propofol analogue has a structure as shown in general formula (G). The propofol analogue of the present application can greatly reduce or eliminate the affinity to GABA receptor, i.e. weaken or eliminate the narcotic property. It targets specific targets and shows effects in improving sleep, regulating blood pressure, relieving vomiting, resisting depression, protecting heart and brain, etc. (G).

The utility model relates to the field of medical nursing, and discloses an anti-odor vomit treatment device which comprises a connecting seat, the top end of the connecting seat is slidably connected with a moving block, the inner wall of the left end of the moving block is elastically connected with a limiting block through a reset spring, and the top end of the moving block is hinged to a movable sleeve through a hinge rod; a conical pipe is fixedly connected to the top end of the movable sleeve, a rotating plate is rotationally connected to the top end of the conical pipe, and a fixed pipe is fixedly connected to the top end of the connecting base. According to the device, the movable sleeve vertically moves along the fixed pipe by moving the movable block and utilizing the fact that the length of the hinge rod is fixed, adjustment can be conducted according to the vomiting height of a patient, discomfort caused by the fact that the patient bows too much during vomiting is avoided, the situation that the patient is prone to splashing during vomiting is avoided, and a worker does not need to hold the collecting barrel by hand; the practicability of the device is improved to a certain extent.

The utility model discloses a vomiting barrel with an angle adjusting structure, which relates to the technical field of medical treatment and public health equipment and comprises a barrel body, an adjusting mechanism is arranged on the outer side of the barrel body and comprises a support frame, a support shaft, an outer gear ring and an inner gear ring, the support frame is arranged on the outer side of the barrel body, and the support shaft is arranged on the support frame. A supporting shaft connected with the can body is rotationally connected into the supporting frame. The adjusting mechanism is arranged, the inner gear ring is clamped with the supporting shaft through the outer gear ring, and the inner gear ring is elastically connected with the supporting frame through the reset spring, so that the inner gear ring can be separated from the outer gear ring by pushing the pushing frame, and at the moment, the barrel body can be pushed according to the requirements of a patient or the actual use scene; and the pushing frame is loosened after the supporting shaft is adjusted to a required inclination angle, so that the inner gear ring is reset under the action of the reset spring and is clamped with the outer gear ring, and the positioning after adjustment is realized so as to be convenient for a patient to use.

The present invention relates to a preparation which can inhibit the initial release of a specific PRS inhibitor and has an effect of preventing nausea or vomiting side effects that occur when an excess amount of an active ingredient is absorbed at the initial stage.