8784results about "Inhalators" patented technology

An aerosol generation device includes a circuit or microcontroller for automatically detecting and adjusting vibration frequency of an electronic transducer to a determined resonance frequency that changes during operation of the device whereby the circuit or microcontroller provides a plurality of tuning signal waves at each of a plurality of time intervals during operation of the electronic transducer from comparison of the current measured for each signal wave during each time interval.

The present invention provides a dry powder formulation of 5-MeO-DMT or a pharmaceutically acceptable salt thereof, and one or more pharmaceutically acceptable carriers or excipients. The formulations described herein may be used to treat a disease or condition, such as depression or alcohol use disorder in a subject in need thereof.

Provided herein are epinephrine spray formulations. Also provided herein are methods of treating anaphylaxis by administering epinephrine spray formulations to subjects in need of such treatment.

A device and method for delivering a fluid as an ejected stream of droplets during inhalation uses inertial filtering to cause a first plurality of droplet particles generated by an ejector mechanism to pass through an airflow exit while a second plurality of droplet particles having a greater mass mean aerodynamic diameter than the first plurality of droplet particles fails to pass through the airflow exit.

Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and / or fully automated.

The present invention provides an inhaler comprising a housing which contains a blister strip having a plurality of blisters which contain powdered medicament for inhalation, a mouthpiece mounted to the housing through which the medicament is inhaled by a user, an indexing and opening mechanism for indexing the blister strip and for opening the blisters which is operated by an actuator, wherein the blister strip is indexed by forward motion of the actuator from a first position to a second position, such as by opening a cover, and is also indexed in the same direction by reverse motion of the actuator from the second positon to the first position, such as by closing the cover.

The present disclosure provides devices for delivery of powder formulations and methods of manufacture and use of such devices.

The present invention provides an inhaler comprising a housing which contains a blister strip having a plurality of blisters which contain powdered medicament for inhalation; a mouthpiece through which the medicament is inhaled by a user; an indexing wheel for indexing the blister strip; an opening mechanism for opening the blisters; an actuator which is movable between a first position and a second position in order to operate the indexing wheel and the opening mechanism; and a coupling mechanism for coupling the actuator to the indexing wheel so that the indexing wheel rotates together with the actuator during part of the motion of the actuator; characterized in that the coupling mechanism comprises a shuttle that rotates on the same axis as, and translates axially relative to, the indexing wheel.

Disclosed is a needle-free applicator that is suitable for administering a solid, amorphous, mono-particulate powder composition into a body cavity of a human patient, which cavity includes a mucosal surface, wherein the applicator comprises:(i) an opaque reservoir comprising said powder composition;(ii) an optional actuating means for generating a force upon actuation of the device by a user; and(iii)a dispensing means through which, following said actuation, said powder composition may be dispensed,wherein said powder composition comprises a pharmacologically-effective dosage amount of an adrenergic receptor modulator, or a pharmaceutically-acceptable salt thereof, encapsulated in an amorphous state along with a pharmaceutically-acceptable carrier material; andwhich powder composition is less than about 4% chemically degraded after storage for:(a) at least about 3 months at 40° C. and 75% relative humidity; and / or(b) at least about 18 months at below about 30° C.; and / or(c) at least about 18 hours at above about 1 million lux of UV light.

An inhaler includes a main body having a canister housing, a medicament canister retained in a central outlet port of the canister housing, and a dose counter having an actuation member for operation by movement of the medicament canister. The canister housing has an inner wall, and a first inner wall canister support formation extending inwardly from a main surface of the inner wall. The canister housing has a longitudinal axis X which passes through the center of the central outlet port. The first inner wall canister support formation, the actuation member, and the central outlet port lie in a common plane coincident with the longitudinal axis X such that the first inner wall canister support formation protects against unwanted actuation of the dose counter by reducing rocking of the medicament canister relative to the main body of the inhaler.

Disclosed is a pharmaceutically-acceptable composition in the form of a solid, amorphous, mono-particulate powder comprising a mixture of:a pharmacologically-effective dosage amount of an adrenergic receptor modulator, or a pharmaceutically-acceptable salt thereof; anda pharmaceutically-acceptable carrier material, which carrier material comprises a maltodextrin with a dextrose equivalent (DE) that is above 15.Compositions are suitable for transmucosal drug delivery, including nasal delivery, by which said compositions may be loaded into a single-use nasal applicator. Compositions are preferably made by way of spray drying and may further include a disaccharide, such as lactose or trehalose which, along with the active ingredient and maltodextrin, may be spray-dried together in combination. Compositions may further comprise one or more alkyl saccharides. Preferred alkyl saccharides include sucrose esters, such as sucrose monolaurate. Preferred adrenergic receptor modulators include epinephrine (adrenaline). The compositions are thus particularly useful in the treatment of allergic reactions, including anaphylaxis.

According to the invention, there is provided a which composition is in the form of an amorphous, mono-particulate powder comprising a mixture of: (a) a pharmacologically-effective dosage amount of at least one biopharmaceutical drug compound; and (b) a pharmaceutically-acceptable carrier material, which carrier material comprises a combination of a disaccharide and a polymeric material. Preferred pharmaceutically-acceptable carriers in this regard include lactose or trehalose and dextrins (e.g. maltodextrins). Compositions may further comprise one or more alkyl saccharides. Preferred alkyl saccharides include sucrose esters, such as sucrose monolaurate. Powder compositions may be produced by spray-drying the various components together in combination.

An aerosol-generating device for generating an aerosol from an aerosol-forming substrate is provided, the aerosol-generating device including: an electrically powered heater element configured to heat the aerosol-forming substrate; a temperature sensor coupled to the electrically powered heater element and configured to sense a temperature of the electrically powered heater element; a power source configured to supply power to the electrically powered heater element and the temperature sensor; and control electronics configured to measure an impedance value of the electrically powered heater element, correlate the measured impedance value with a value of impedance determined from the temperature of the electrically powered heater element as sensed by the temperature sensor, and control the supply of power to the electrically powered heater element based on the correlation. A method of controlling an electrically powered heater element of the aerosol-generating device is also provided.

A mist inhaler device (200) for generating a mist including a therapeutic for inhalation by a user. The device includes a mist generator device (201) and a driver device (202). The driver device (202) is configured to drive the mist generator device (201) at an optimum frequency to maximise the efficiency of mist generation by the mist generator device (201).

The present disclosure provides a biometrically controlled handheld medication dispensing device. The device includes a housing containing a cartridge carrier, designed with a specific connector to align with a medication cartridge. Notably, the device also includes a biometric authentication component that works in conjunction with an activator mechanism. When operated and upon user authentication, the activator mechanism causes the cartridge carrier to move the medication cartridge between a stored position and a dispensing position, where it can be compressed to safely and efficiently dispense medication to a user.

A nasal spray device comprises a non-pressurized reservoir for containing a liquid formulation; a spray nozzle; and a manually energizable pump, configured to pressurize a quantity of said liquid formulation and causing the liquid formulation to move through the spray nozzle such that the liquid formulation is discharged from the spray nozzle as an aerosol spray. The spray nozzle comprises a membrane having a plurality of micropores of a substantially identical size below 8 micron and beyond 3 micron through which the liquid formulation passes as the liquid formulation is discharged from the device. Said membrane is configured to release said dose of said liquid formulation in a period of at least 500 milliseconds as a conically shaped plume having an apex. An energy of less than 20 Joule / gram is being dissipated in the liquid to preserve the molecular integrity of macromolecules within the liquid.

An electronically actuated droplet delivery device with a mouthpiece for inhaling fluid droplets includes an ejector mechanism having an electronic actuator operably coupled to an aperture plate. A fluid reservoir provided fluid to the ejector mechanism through a surface tension plate that increases contact between the fluid from the fluid reservoir and the aperture plate.

An electronic droplet delivery device having a mouthpiece of inhalation of droplets includes an aperture plate with a plurality of openings coupled to a piezoelectric actuator. A fluid reservoir supplies a solution with nicotine to the aperture plate for ejection out of the mouthpiece in a droplets stream.

The utility model discloses an automatic cover rebounding structure of a medicine distribution device, which comprises a distributor shell, a turning cover and a torsion piece, the turning cover is rotatably arranged on the distributor shell, and the turning cover can reciprocate between an initial position and a final position; the turning part is connected with the distributor shell and the turning cover and can turn around the rotating axis of the turning cover, and the turning cover is tightly pressed to the initial position through the turning part without external force. According to the automatic cover rebounding structure of the medicine distribution device, the turning cover can be automatically reset, a user can conveniently use the automatic cover rebounding structure, and meanwhile the problem that an outlet is polluted due to the fact that the turning cover forgets to be closed or is not tightly closed is effectively solved; in addition, the turning cover has the in-place locking function, and medicine dosage changes caused by accidental movement of the turning cover in the medicine taking process can be avoided.

A system for delivering an aerosolized drug to a patient. The system includes a holding chamber (108), suitable to contain a drug to be aerosolized, and a connect element (100) having first and second ends, the second end being opposite to the first end and being suitable to be connected to the holding chamber (108). The connect element further comprises one or more mating mechanism (102, 104, 112, 114, 118) proximal its first end. The system can also include a mouthpiece (400), a drug assembly (200) including a drug housing (216) and a drug cartridge (300), and a vaporizer (500).

A capsule for an aerosol-generating device includes a housing. The housing includes an inner frame defining an opening. The housing defines at least one air inlet and at least one air outlet. The capsule also includes an aerosol-forming substrate at least partially within the opening, and a heater supported by the inner frame and extending across at least a portion of the opening. The at least one air inlet, the opening, and the at least one air outlet collectively form at least one airflow pathway through the capsule. The airflow pathway is longer than a thickness of the capsule.

A hookah device (202) which attaches to a hookah (246). The hookah device (202) comprises a plurality of ultrasonic mist generator devices (201) for generating a mist for inhalation by a user. The hookah device (202) comprises a driver device (202) which controls the mist generator devices (201) to maximize the efficiency of mist generation by the mist generator devices (201) and optimize mist output from the hookah device (202).

Apparatus, methods, and systems for delivery and administration of pharmaceutical, therapeutic and cosmetic substances to users. The method includes providing a removable capsule having an atomizer, inserting the removable capsule in a channel of a base unit of a device. The channel is in fluid communication with a mixing chamber of the base unit, and the base unit defines openings on the base unit configured to receive a portion of a conduit and a removable air mover unit. Further, the method includes dispensing, using the atomizer, the at least one medication from the removable capsule to the mixing chamber of the base unit, and using the removable air mover unit, causing air and the at least one medication within the mixing chamber to be conveyed from the mixing chamber to the conduit such that air and the at least one medication dispensed from the removable capsule exits the conduit.

The present invention provides a dry powder inhaler comprising: one or more doses of powdered medication; an outlet through which a user may inhale a dose of medication; an airway, and a mixing element located in the airway When a user inhales on the outlet, medication is entrained in an air flow and flows through the airway and out through the outlet. The mixing element is in the form of three generally orthogonal generally circular discs with a common centre.

Disclosed herein is a device configured to impart flavoring to an airstream admitted the device prior to the airstream reaching an aerosol generator of the device, the device thereby operable to deliver a flavored aerosol from an outlet.

Vaporizers and vaporizer systems, which can include a device in communication with a vaporizer, can include one or more features related to control of functions and / or features of the vaporizer, identification of a cartridge and / or a vaporizable material in the cartridge, data exchange (either one-way or two-way) between a cartridge and a vaporizer with which the cartridge is engaged, and the like.

The invention relates to a heating control method, aerosol generating equipment and a computer readable storage medium. The control method is used for the aerosol generation equipment, the aerosol generation equipment comprises a supporting assembly, a first laser and a second laser, the supporting assembly is used for installing an aerosol generation product, and the light emitting sides of the first laser and the second laser face the supporting assembly. The heating control method comprises the steps of controlling the first laser to emit detection laser; acquiring a detection feedback signal sent by the second laser, wherein the detection feedback signal is generated when the second laser is irradiated by the reflected detection laser; determining whether the aerosol generating product is mounted on the supporting assembly according to the detection feedback signal; under the condition that the aerosol generating article is installed on the supporting assembly, the first laser and / or the second laser are / is allowed to emit the heating laser to heat the aerosol generating article. According to the heating control method, the laser is allowed to emit high-power heating laser only when it is determined that the aerosol generating product is installed on the supporting assembly.

Vaporizers and vaporizer systems, which can include a device in communication with a vaporizer, can include one or more features related to control of functions and / or features of the vaporizer, identification of a cartridge and / or a vaporizable material in the cartridge, data exchange (either one-way or two-way) between a cartridge and a vaporizer with which the cartridge is engaged, and the like.

A refillable liquid tip or cartridge for a vaping device includes a capacitive sensor plate located in a tip liquid reservoir. The liquid refilling device provides the liquid sucked from the refilling bottle to the vapour device; the refilling device comprises a capacitance measuring circuit; a microcontroller uses data from the capacitance measurement circuit to determine whether a liquid level in the tip liquid reservoir is above or below a threshold level, if below, activates a liquid pump in the refill device to draw liquid from the refill vial, and if not, activates a liquid pump in the refill device to discharge liquid from the refill vial. And pumping the liquid through the vapour device and up into the tip liquid reservoir. The pumping is stopped once the liquid reaches the threshold level.

Provided are an aerosol generating apparatus including a cigarette insertion portion into which a cigarette is insertable; and a vaporizer configured to heat a liquid composition to generate aerosol and discharge the generated aerosol toward the inserted cigarette such that the generated aerosol passes through the cigarette inserted into the cigarette insertion portion, and a cradle for receiving the aerosol generating apparatus.