2561 results about "Nicotine" patented technology

The invention relates to a non-smokable electronic spray cigarette which only comprises nicotine without harmful tar. The cigarette includes a smoke mouth integer comprised with a shell, a cell, a high frequency ionzer, nicotine solution storage and its container, control circuit, a display screen, a human contact sensor, a piezoelectric supersound atomizer, a high temperature vaporization nozzle and attachments, an electro-thermal vaporization nozzle installed in the air suction end of the shell goes through an electric control pump or a valve with a measuring chamber and a liquid storage container which contains nicotine solution and is connected to the electric control pump or a valve with a one-way flow valve, the control circuit plate has four export ends individually connected with the high frequency ionizer, electric heater, pump or valve and the display screen, a human resistence sensor and an air flow sensor are connected to the input end of the control circuit. The advantages of the present invention are smoking without tar, reducing the cancerogenic risk, the user still feel smoking and experiercing the excitement, the cigarette is no need to be lit and is no fire danger.

The invention relates to an electronic atomization cigarette which only contains nicotine without harmful tar. The electronic atomization cigarette includes a shell and a mouthpiece. The external wall of the shell has an air inlet. An electronic circuit board, a normal pressure cavity, a sensor, a vapor-liquid separator, an atomizer, a liquid-supplying bottle are sequentially provided within the shell, wherein the electronic circuit board comprises an electronic switching circuit and a high frequency generator. A stream passage of the sensor is provided on one side of the sensor, and a negative pressure cavity is provided in the sensor. The atomizer and the liquid-supplying bottle is in contact with each other. An atomization cavity is arranged in the atomizer. A retaining ring for locking the liquid-supplying bottle is provided between one side of the liquid-supplying bottle and the shell, and an aerosol passage is provided on the other side of the liquid-supplying bottle. The air inlet, normal pressure cavity, vapor-liquid separator, atomizer, aerosol passage, gas vent and mouthpiece are sequentially interconnected.

An improved electronic evaporable substance delivery device delivers nicotine-containing vapor to a user from a smoking device. The smoking device comprises a case having therein a power source, microprocessor, heating element and nicotine-containing cartridge. Microprocessor-controlled heating of the heating element causes air passing thereover to be heated. Passage of the heated air in proximity of the cartridge causes boiling of cartridge contents, and the release of a nicotine-containing vapor. A user may ingest the nicotine-containing vapor via a mouthpiece located at a first end of the case.

The present invention relates to an electronic atomization cigarette which only contains nicotine without harmful tar. The electronic atomization cigarette includes a shell and a mouthpiece. The external wall of the shell has an air inlet. An electronic circuit board, a normal pressure cavity, a sensor, a vapor-liquid separator, an atomizer, a liquid-supplying bottle are sequentially provided within the shell, wherein the electronic circuit board comprises an electronic switching circuit and a high frequency generator. A stream passage of the sensor is provided on one side of the sensor, and a negative pressure cavity is provided in the sensor. The atomizer and the liquid-supplying bottle is in contact with each other. An atomization cavity is arranged in the atomizer. A retaining ring for locking the liquid-supplying bottle is provided between one side of the liquid-supplying bottle and the shell, and an aerosol passage is provided on the other side of the liquid-supplying bottle. The air inlet, normal pressure cavity, vapor-liquid separator, atomizer, aerosol passage, gas vent and mouthpiece are sequentially interconnected. The advantages of the present invention include smoking without tar, significantly reducing the cancerogenic risk. Furthermore, users still feel as if they are smoking and experiencing the same excitement, and the cigarette is no need to be lit and is no fire risk.

The present invention relates to an electronic atomization cigarette which only contains nicotine without harmful tar. The electronic atomization cigarette includes a shell and a mouthpiece. The external wall of the shell has an air inlet. An electronic circuit board, a normal pressure cavity, a sensor, a vapor-liquid separator, an atomizer, a liquid-supplying bottle are sequentially provided within the shell, wherein the electronic circuit board comprises an electronic switching circuit and a high frequency generator. A stream passage of the sensor is provided on one side of the sensor, and a negative pressure cavity is provided in the sensor. The atomizer and the liquid-supplying bottle is in contact with each other. An atomization cavity is arranged in the atomizer. A retaining ring for locking the liquid-supplying bottle is provided between one side of the liquid-supplying bottle and the shell, and an aerosol passage is provided on the other side of the liquid-supplying bottle. The air inlet, normal pressure cavity, vapor-liquid separator, atomizer, aerosol passage, gas vent and mouthpiece are sequentially interconnected. The advantages of the present invention include smoking without tar, significantly reducing the cancerogenic risk. Furthermore, users still feel as if they are smoking and experiencing the same excitement, and the cigarette is no need to be lit and is no fire risk.

A smokeless cigarette that provides for the dispensation of vitamins to the user by way of a vitamin infused cartridge whereby a liquid mixture of vitamins and / or botanicals are injected into a liquid supplying bottle within the nicotine cartridge for inhalation and absorption by the user.

A smokeless pipe comprises a bowl (1), a shank (2), a stem (3) with a bit (4) and an air channel (5) inside of the pipe, which is used for placing a carrier of a nicotine-containing or flavoring agent (10) and a heating unit (7) connected to a power supply (8). According to the invention at least one of elements (7) of a heating unit is arranged in the stem (3) and is shifted to the bit (4). The invention ensures preservation of the health of a pipe smoker while fully simulating the process of smoking.

The present disclosure generally relates to compositions, and related devices and methods, useful in vaporizing devices such as electronic cigarettes. The composition may comprise nicotine, at least one solvent, and at least one ion pairing agent, and may be vaporized to form a condensation aerosol, wherein inhalation of the aerosol allows for deposition of nicotine with the respiratory system, including deep lung deposition. The vaporizing device may comprise a vaporization unit, a battery, and an integrated circuit coupled to the battery, wherein the integrated circuit is configured to control the battery for rapid initial vaporization without overheating, producing thermal degradation products, or draining battery energy. The battery may operate with pulse width modulation for at least a portion of the time the vaporizing device is being used.

This invention encompasses methods for the treatment and prevention of disorders that include, but are not limited to, eating disorders; weight gain; obesity; irritable bowel syndrome; obsessive-compulsive disorders; platelet adhesion; apnea; affective disorders such as attention deficit disorders, depression, and anxiety; male and female sexual function disorders; restless leg syndrome; osteoarthritis; substance abuse including nicotine and cocaine addiction; narcolepsy; pain such as neuropathic pain, diabetic neuropathy, and chronic pain; migraines; cerebral function disorders; chronic disorders such as premenstrual syndrome; and incontinence. The invention further encompasses pharmaceutical compositions and dosage forms which comprise optically pure (+) sibutramine, optionally in combination with a phosphodiesterase inhibitor or a lipase inhibitor.

A novel composition for the use as snuff in the oral cavity, the composition comprising tobacco and / or a tobacco substitute encapsulated in a membrane material comprising one or more membranes at least one of which being water permeable and water-insoluble. A novel composition enables a selective release of e.g. nicotine while it at the same time reduces the release of substances, which normally lead to unwanted side effects. The novel compositions may be used as a healthier alternative to snuff and other tobacco products such as, e.g., cigarettes, cigars and pipe. Methods for giving up smoking, reducing nicotine craving, reducing side effects normally related to smoking and snuffing of tobacco as welt a method for the preparation of a composition according to the invention.

The disclosure relates to a method of enhancing nicotine or other medicament concentrations in a gaseous carrier. The methods are adaptable to the delivery of nicotine or other medicaments for therapeutic effect in various diseases, in particular nicotine for tobacco product use cessation, substitution and / or harm reduction. The disclosure further relates various devices and device design principles for practicing these methods.

Rapidly dissolving, oral film preparations for rapid release of an active agent in the oral cavity, in particular, rapidly dissolving oral films comprising a nicotine active which achieve good transbuccal absorption and provide nicotine craving relief to an individual are disclosed herein.

A nicotine inhalation pipe includes a rodlike nicotine holder (1) and a mouthpiece (2) attached to one end of the holder (1). The holder (1) includes a transparent outer tube (3) having a plurality of openings (36) at both ends thereof, liquid absorbent granules (34) filled in the outer tube (3), and a nicotine inhalation path formed by gaps between the liquid absorbent granules (34) and gaps between the inner peripheral surface of the outer tube (3) and the liquid absorbent granules (34). The liquid absorbent granules (34), which are made of porous silica gel and in which a nicotine solution is absorbed, permit nicotine to be vaporized from the nicotine solution.

An electronic cigarette is provided in two or three sections. One section is a reusable barrel containing the electrical components, including a rechargeable battery and a heater or atomizer. Another section may include the atomizer and a replaceable and disposable cartridge having the desired volatile substance, such as nicotine, a medicament, and / or a flavoring agent.

It has been discovered that the stimulation of beta-adrenergic receptors, which activate cAMP formation, give rise to increased APP and GFAP synthesis in astrocytes. Hence, the in vitro or in vivo exposure of neuronal cells to certain compositions comprising beta-adrenergic receptor ligands or agonists, including, e.g., norepinephrine, isoproterenol and the like, increases APP mRNA transcription and consequent APP overproduction. These increases are blocked by beta-adrenergic receptor antagonists, such as propranolol. The in vitro or in vivo treatment of these cells with 8Br-cAMP, prostaglandin E2 (PG E2), forskolin, and nicotine ditartrate also increased APP synthesis, including an increase in mRNA and holoprotein levels, as well as an increase in the expression of glial fibrillary acidic protein (GFAP). Compositions and methods are disclosed of regulating APP overexpression and mediating reactive astrogliosis through cAMP signaling or the activation of beta-adrenergic receptors. It has further been found that the increase in APP synthesis caused by 8Br-cAMP, PG E2, forskolin, or nicotine ditartrate is inhibited by immunosuppressants or anti-inflammatory agents, such as cyclosporin A, and FK-506 (tacrolimus), as well as ion-channel modulators, including ion chelating agents such as EGTA, or calcium / calmodulin kinase inhibitors, such as KN93. The present invention has broad implications in the alleviation, treatment, or prevention of neurological disorders and neurodegenerative diseases, including Alzheimer's Disease.

The invention relates to devices and methods for delivering nicotine and / or other alkaloids from tobacco, other plants and other natural sources. More particularly, the invention relates to devices and methods for delivering an aerosol of nicotine to a user's lungs without combustion of the nicotine source materials.

A device for the administration of basic active agents, such as nicotine, to the human or animal body. The active agents are administered by inhalation. The device comprises a first preparation containing a nicotine base or / and a further basic active agent and, a second or further preparations. At least one preparation contains at least one volatile acid suitable for inhalation.

A cartomizer for an electronic cigarette having an elongated, hollow body with a mouthpiece in a first end and a battery coupling in an opposite second end. An atomizing coil is disposed in the body generally perpendicular to a longitudinal axis of the cartomizer and has positive and negative terminal leads pressfit connected to positive and negative terminals separated by an insulative spacer in the battery coupling. A fibrous wick is inserted inside the atomizing coil and a cloth tube is disposed generally parallel to the longitudinal axis of the cartomizer and extends from the atomizing coil to the mouthpiece. A volatile liquid mixture of preferably 80% propylene glycol and 20% veggie glycol with liquid nicotine and / or flavoring is disposed in the body.

Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.

The present invention generally relates to tobacco and tobacco products having a reduced amount of nicotine and / or tobacco specific nitrosamines (TSNA). More specifically, several ways to make tobacco plants that have reduced nicotine and TSNA levels have been discovered. Embodiments include tobacco harvested from said tobacco plants, cured tobacco from said tobacco plants, tobacco products made with said cured tobacco and methods of making these compositions.

Therefore, the technological essential point of the invention is that it is aimed at providing e-cigarette with battery replacement type that allows a quick recharge and replacement of a battery when the battery is dead or out of order by making a condition that only battery could be separately drawn out in the inside of power supply part in which opening and closing members are formed in e-cigarette that a user inhales the smoke that is generated by burning liquid containing nicotine.

Nicotine-containing pharmaceutical compositions wherein nicotine is absorbed into and / or adsorbed onto cellulose of non-seed organism origin, especially cellulose from algae, bacteria and / or fungi.

The invention claims a combined multifunctional electronic simulated cigarette, comprising an indicator, wherein the indicator is provided with a air inlet hole; one end of the indicator is connected with one end of an aroma generator; a first switch and a first battery are arranged between the indicator and the aroma generator; a solid aromatic substance is arranged in the aroma generator and is provided with electric heating wires; the other end of the aroma generator is connected with one end of a smoke capsule; solid adsorption cotton adsorbed with nicotine is arranged in the smoke capsule; the other end of the smoke capsule is connected with a suction nozzle which is provided with a suction hole. The invention can provide users with aromatic gases, nicotine component and simulated smoke simultaneously; and the users can respectively choose to inhale the aromatic gases, the nicotine component and the simulated smoke according to the needs, and the invention can meet the needs of the users or the smoking quitters in different stages, help the users to gradually reduce the suction amount of nicotine, and finally achieve the purpose of not taking in nicotine.

It has been discovered that the stimulation of beta -adrenergic receptors, which activate cAMP formation, give rise to increased APP and GFAP synthesis in astrocytes. Hence, the in vitro or in vivo exposure of neuronal cells to certain compositions comprising beta -adrenergic receptor ligands or agonists, including, e.g., norepinephrine, isoproterenol and the like, increases APP mRNA transcription and consequent APP overproduction. These increases are blocked by beta -adrenergic receptor antagonists, such as propranolol. The in vitro or in vivo treatment of these cells with 8Br-cAMP, prostaglandin E2 (PG E2), forskolin, and nicotine ditartrate also increased APP synthesis, including an increase in mRNA and holoprotein levels, as well as an increase in the expression of glial fibrillary acidic protein (GFAP). Compositions and methods are disclosed of regulating APP overexpression and mediating reactive astrogliosis through cAMP signaling or the activation of beta -adrenergic receptors. It has further been found that the increase in APP synthesis caused by 8Br-cAMP, PG E2, forskolin, or nicotine ditartrate is inhibited by immunosuppressants or anti-inflammatory agents, such as cyclosporin A, and FK-506 (tacrolimus), as well as ion-channel modulators, including ion chelating agents such as EGTA, or calcium / calmodulin kinase inhibitors, such as KN93. The present invention has broad implications in the alleviation, treatment, or prevention of neurological disorders and neurodegenerative diseases, including Alzheimer's Disease.

In order to use a commercially available cigarette or cigar as it is, vaporize nicotine from the tobacco leaves, and enable inhalation of the vaporized nicotine without burning the product, a non-combustion smoking tool comprises a slender heater 1 having a sharp end which is directly inserted into a commercially available cigarette or cigar 100 to directly heat the leaves of the cigarette or cigar by the heater so as to vaporize nicotine contained in the tobacco leaves and enable inhalation of the vaporized nicotine.

Aspects of the present invention concern tobacco having reduced nicotine and nitrosamines, which is used to manufacture consumer tobacco products, and methods to produce such tobacco. More specifically, embodiments include methods to reduce nicotine and nitrosamines in tobacco crops by applying auxin, auxin analogs, and jasmonate antagonists during the cultivation of such tobacco crops. Tobacco generated using said methods and consumer tobacco products obtained therefrom are also embodiments.

A method and composition to help persons reduce or quit smoking is disclosed, employing raw tobacco leaves, or tobacco fluid extract, or food grade tobacco like flavor and aroma, and Antioxidants, with or without and SAMe and caffeine. All ingredients can be in a micro-powdered or liquid form, for buccal administration. The composition can be in a tablet or capsule that is intended to be slowly sucked and dissolved in the mouth, and that delivers the nicotine, caffeine or SAMe, proved to be effective in alleviating smoking withdrawal symptoms. The composition can also be embedded inside a soft squeezable plastic cigarette for simulated smoking, providing additional periodic doses of nicotine, caffeine and SAMe to satisfy cravings for cigarettes.

The present invention provides compositions comprising a conjugate of a hapten with a carrier in an ordered and repetitive array, and methods of making such compositions. The conjugates and compositions of the invention may comprise a variety of haptens, including hormones, toxins and drugs, especially drugs of addiction such as nicotine. Compositions and conjugates of the invention are useful for inducing immune responses against haptens, which can use useful in a variety of therapeutic, prophylactic and diagnostic regimens. In certain embodiments, immune responses generated using the conjugates, compositions and methods of the present invention are useful to prevent or treat addiction to drugs of abuse and the resultant diseases associated with drug addiction.

Compositions comprising nicotine, which compositions provide a rapid release of nicotine. Nicotine is present in the form of a nicotine-cellulose combination. The compositions are designed for administration to the oral cavity where the nicotine is rapidly released from the composition and available for absorption through the oral mucosa. The compositions are lozenges and have excellent storage stability.

A non-combustion smoking tool is usable with a commercial cigarette or cigar as it is, the tool vaporizes nicotine from the tobacco leaves and enables inhalation of the vaporized nicotine without burning the product. The non-combustion smoking tool has a heater to be used which includes a coil part and a linear part to be inserted into a commercial cigarette or cigar, wherein the linear part preheats the tobacco leaves, and the coil part heats air around the coil part so that, when a smoker inhales, the heated air around the coil part passes through the tobacco leaves so as to vaporize nicotine contained in the tobacco leaves and enable inhalation of the vaporized nicotine.