31 results about "Natural source" patented technology

This invention relates to a bioactivator based on L-proline structural modification, its synthesis method, and its application, belonging to the field of agricultural chemistry. The activator employs a biomimetic molecular design strategy, prepared through the splicing of active structural units. L-proline's unique natural source advantage and the important active unit fragment N,N-diethylethanolamine from DA-6 undergo an esterification reaction to yield 2-(diethylamino)ethyl-L-proline ester. Bioactivity experiments were conducted on wheat and soybean, respectively. The results showed that this compound can promote plant growth at low concentrations, exhibiting significantly better growth effects than the blank control in terms of germination rate, root length, and stem length. Furthermore, the preparation process of this invention is simple, low-cost, and easily scalable for industrial production, and it possesses good environmental compatibility. Its unique natural source advantage provides a new option for activator development and has significant potential for agricultural development.

The application belongs to the technical field of cell culture, and particularly relates to a temperature-sensitive cell three-dimensional culture support, which comprises temperature-sensitive hydroxypropyl chitin, the molecular weight of the temperature-sensitive hydroxypropyl chitin is 15,000-300,000 Da, and the degree of deacetylation (DD) is 35%-65%. The support material is temperature-sensitive hydroxypropyl chitin prepared by derivatization of chitosan of a natural source through a specific process, and can be used for three-dimensional culture of cells. The temperature-sensitive hydroxypropyl chitin is used for three-dimensional culture of cells, and can significantly reduce the culture cost, improve the convenience and the viability of the cultured cells.

The present invention relates to a novel process for crosslinking polysaccharides of natural origin in an aqueous-organic medium and topical formulations comprising the same. The process of the present invention produces gels of natural origin polymers more concentrated or free of added water and in powder form, suitable for thickening, stabilizing or emulsifying cosmetic or pharmaceutical topical formulations or for suspending solid particles therein.

The present application relates to the field of medicine manufacturing, and relates to a preparation method of natural source cholesterols for injection, which comprises the following steps: taking fish oil, cooling and winterizing, taking the lower sediment, heating to dissolve it into clear winterization fraction, adding the winterization fraction into a chromatographic column filled with mixed filler of adsorbent and filter aid which are mixed uniformly in a physical way to perform circulation chromatography, emptying the winterization fraction after the circulation ends, adding eluent to the chromatographic column, and recovering the solvent after the eluent is combined to obtain cholesterols concentrate. The cholesterols concentrate is added with first crystallization solvent to recrystallize and refine twice, the cholesterols crude product after recrystallization is taken and added with second crystallization solvent to recrystallize and refine, and the product is dried under reduced pressure to obtain cholesterols for injection. The present application solves the technical problem of preparing cholesterols for injection from fish oil, is suitable for large-scale industrialization of cholesterols, can be applied to preparation of complex preparations such as liposomes, and improves the safety of drug use.

The present invention relates to systems with emergent properties, in particular suitable for use as lubricants, for example for the manufacture of tablets and capsules, and as technical aids for the operation of processing machines for the preparation of said materials, and provides novel natural systems with lubricating action, suitable for use as lubricants, 100% of natural origin, compositions containing them, their uses and methods of preparation. In particular, the present invention provides novel natural systems with lubricating activity, suitable for use as lubricants, 100% consisting of products of natural origin, not chemically synthesized, consisting of powders of seeds-containing fruits or seeds, wherein said fruits or seeds are characterized by the presence of fatty acids, optionally in combination with natural gums, to replace the common chemical origin powder lubricants.

This application provides a novel lipopeptide molecule, its preparation method, and its applications. The novel lipopeptide molecule of this application possesses ultra-low interfacial tension, surface tension, and extremely strong wetting reversal properties. Compared with naturally derived lipopeptide compounds, it exhibits stronger stability and higher surface activity, and has broad application prospects in the field of petroleum extraction.

The application belongs to the technical field of animal disease prevention and control, and discloses application of a traditional Chinese medicine monomer, i.e., a perillyl alcohol, in preparation of a medicine for preventing or treating a pseudorabies of pigs. The application verifies the role of the perillyl alcohol in inhibiting a pig pseudorabies virus infection process and explores the application value of the perillyl alcohol in resisting the pig pseudorabies virus, and provides a theoretical basis and practical guidance for prevention and control of the PRV. In addition, the perillyl alcohol is a natural source medicine, has the advantages of safety, few side effects, low metabolic residues and no pollution, and has good popularization and application value.

This invention discloses a method for preparing the natural product mycenolide A, comprising the following steps: mixing compound 2, IBX oxidant, and solvent to carry out an oxidation reaction to obtain the natural product mycenolide A; the structural formulas of compound 2 and the natural product mycenolide A are as follows: This invention proposes and realizes for the first time an efficient total synthesis strategy for all possible chiral isomers of mycenolide A, not only solving the scientific problem of the scarcity of natural mycenolide A and its unknown absolute configuration, but also providing solid technical support and material guarantee for subsequent evaluation of neuroprotective activity and development of related original drugs due to its excellent synthetic efficiency and comprehensive coverage of chiral isomers.

This invention discloses a fingerprint development reagent based on natural AIE compounds and precipitated silica, its preparation method, and its application, belonging to the field of forensic identification technology. The reagent is a particulate suspension comprising precipitated silica, natural AIE compounds, a surfactant, and a solvent. During preparation, the surfactant is dissolved in the solvent, the natural AIE compound is added and dissolved, and then precipitated silica is added in batches with stirring to obtain a uniform and stable suspension. This invention uses naturally derived AIE active substances, which are non-toxic, environmentally friendly, and low-cost, avoiding the biotoxicity and complex preparation process of traditional synthetic dyes. It also effectively solves the problems of dust pollution and poor compatibility with moist objects in powder development methods. It achieves high-contrast, high-definition fluorescence development of latent fingerprints on both dry and moist, non-permeable surfaces. The preparation process is simple and controllable, easy to scale up, and has good application prospects in rapid on-site detection fields such as criminal investigation and forensic identification.

The embodiment of the present application provides a kind of positive ganoderma lucidum polysaccharide-based hydrogel and its preparation method and application, wherein the positive ganoderma lucidum polysaccharide-based hydrogel includes the following components by weight: ganoderma lucidum polysaccharide extract 10~100 parts;Silane coupling agent with amino functional group 0.5~10 parts;Epoxide compound 1~10 parts;Radical initiator 0.1~1 parts.The positive ganoderma lucidum polysaccharide-based hydrogel and its preparation method and application provided by the embodiment of the present application, by selecting natural source ganoderma lucidum polysaccharide as basic material, its inherent biocompatibility and biological activity are maintained.The positive charge functional group introduced by chemical modification significantly enhances the interaction ability of hydrogel with negatively charged biomolecules.The structure of hydrogel is optimized by accurately controlling the chemical modification and crosslinking process, so that it has better mechanical strength and stability.

The present invention relates to a process of preparing alkali metal carbonate, more particularly to alkali metal carbonate having lowered bulk density. It is desired to provide a low-density sodium carbonate which is also environmentally friendly and involves lower green-house gas emissions while maintaining desirable properties. It is desired to provide an alkali metal carbonate which has low bulk density and is obtained from natural source. The present inventors have found that when an aqueous solution of dense sodium carbonate is mixed with a copolymer of acrylic acid and maleic acid, with specific mole ratio of maleic acid to acrylic acid, the treated sodium carbonate surprisingly has a lowered bulk density and preferably has improved dispersibility, liquid carrying capacity and enhanced porosity.

The present application relates to the technical field of polysaccharide extraction, in particular to a preparation method of purified polysaccharides from Lycium barbarum and application thereof, the molecular weight of the polysaccharides ranges from 5000 to 50000 Da, and the purity is greater than or equal to 98%, the polysaccharides comprise glucose, rhamnose and mannose, wherein the molar ratio of glucose, rhamnose and mannose is 3.2-4.0:1.8-2.5:1.0-1.5; the preparation method is green and environmentally friendly, no harmful reagent residues, high polysaccharide activity retention rate, high purification efficiency, high bioavailability, low toxicity, natural source and clear mechanism of action.

The application discloses application of a Portulaca oleracea extracellular vesicle in resisting acne and regulating acne microecological flora. The Portulaca oleracea extracellular vesicle PDEVs provided by the application can significantly inhibit growth of Propionibacterium acnes, and has obvious bactericidal effect under a lower MIC condition, has less influence on skin beneficial bacteria, is helpful to maintaining or regulating skin microecological balance, and has the advantage of selectively regulating skin flora. Meanwhile, the PDEVs can significantly reduce mRNA expression levels of inflammatory factors IL-6, IL-8, IL-1beta and TNF-alpha of HaCaT cells under stimulation of inactivated Propionibacterium acnes and intracellular reactive oxygen species ROS levels, thereby reducing inflammatory reaction and oxidative stress reaction; the PDEVs have a synergistic effect in regulating skin microecology, inhibiting inflammatory reaction and relieving oxidative stress, have good biocompatibility and safety, and provide more choices for developing natural source active ingredients for preventing or improving acne.

The application provides a postharvest preservation method of mango, which comprises the following steps: S1. picking and pretreatment, S2. short-wave ultraviolet mild irradiation treatment, S3. preservative solution immersion and storage. The preservative solution is composed of phyllium extract solution, mango leaf extract solution, arginine grafted modified chitosan, glacial acetic acid and sterile water. Through the synergistic process of the short-wave ultraviolet mild irradiation and the preservative solution immersion, combined with the multiple effects of the modified chitosan coating and the plant extract, the mango can be stored for 30 days under the condition of 13-15 DEG C and 85-90% relative humidity, the good fruit rate is still kept to be more than 90%, and the weight loss rate is less than 5%, so that the industry problems that the mango is prone to rot and fast water loss after harvesting are effectively solved. The components of the preservative solution used in the application are all safe natural sources, no chemical synthetic fungicides are used in the whole process, there is no pesticide residue risk, and the green preservation and food safety requirements are met.

This invention belongs to the field of agrochemical technology, specifically relating to the synthesis and application of a bioactivator based on L-proline structural modification. Using naturally sourced and inexpensive L-proline as a raw material, this invention synthesizes the target compound, triethanolamine tri-L-proline ester, through a one-step esterification reaction for structural modification. Bioactivity experiments confirm that this compound can significantly improve the germination rate of crops such as wheat and soybeans at low concentrations, and promote root and stem growth, with regulatory effects far superior to the blank control. Furthermore, this compound has a simple production process, low raw material cost, and excellent water solubility, making it easy to achieve large-scale industrial production. This is of great significance for reducing agricultural production costs, improving crop yield and quality, and developing green and environmentally friendly activators.

The present utility model relates to a collagen-enriched natural souring seasoning powder made from processed chicken feet and kamias. The composition uses chicken feet collagen powder as a value-added ingredient and dehydrated kamias powder as a natural source of sour flavor. These are blended with selected seasoning ingredients such as salt, garlic powder, onion powder, black pepper, and food-grade anti-caking starch to produce a dry savory and tangy seasoning powder. The product may be used to enhance the taste of soups, sauces, marinades, meat dishes, vegetable dishes, fried foods, and other food preparations. This utility model provides a practical way to make use of chicken feet and kamias as useful food ingredients while producing a flavorful seasoning powder without primarily relying on artificial chicken flavoring, synthetic souring agents, or preservative additives.

The present disclosure belongs to the technical field of biological medicines. Disclosed is a novel ceramide which has a structure represented as formula IFurther disclosed in the present disclosure are a preparation method for and the use of the ceramide. The present disclosure uses naturally-sourced and readily-available 10-hydroxycarboxylic acid as a starting raw material to construct the ceramide having a novel structure. The preparation method has a simple and convenient synthetic route and is suitable for large-scale production. Meanwhile, the obtained ceramide shows more excellent effects in the aspects of tissue repair, anti-inflammatory repair, tissue healing, moisturizing and anti-aging, and thus can be used in the fields of health care products, cosmetics and drugs.

A hydrogel of one aspect has an excellent level of thickening performance even at a low concentration, has good dispersibility, has an outstanding level of water holding capacity compared to other thickeners, and has a non-sticky excellent feeling when used. In addition, the hydrogel not only has an excellent ability of dispersing nanoparticles, but also a production process therefor is relatively simple and does not require much energy. In addition, since the hydrogel is naturally crosslinked with citric acid, which is a naturally derived component, the hydrogel may be widely applied in the field of cosmetics pursuing green and clean beauty.

The application discloses a kind of schizochytrium high DHA low DPA oil fermentation control method and application, through the time axis joint control strategy of "resource release-pathway bias-state reinforcement": in early and middle fermentation, small molecule of natural source is added in batches, and FAS competition path is moderately inhibited;In key time window, the programmed ventilation and stirring cascade control of "normal oxygen supply-low oxygen supply induction-recovery oxygen supply" is implemented to maintain target DO interval;And 28-34 ℃ temperature ladder is used to up-regulate and can be linked with feeding to strengthen metabolic state switching and fatty acid spectrum formation.After the above-mentioned joint regulation, DHA 67.5%, DPA 4.5% and oil yield 84.3 g / L can be stably obtained in 5 L fermenter;Scaling up to 500 L fermenter, DHA 68.3%, DPA 4.8% and oil yield 89.7 g / L can still be obtained.The method is safe and simple, and the parameters can be engineered to replicate, easy to scale up and migrate, can significantly reduce the burden of DHA / DPA separation and purification and improve the product specification stability, with good industrial application prospect.

Disclosed herein are edible compositions containing a blue colorant having a phycocyanin content of at least 35 wt.% or at least 40 wt.% and uses thereof. The blue colorant can be derived from a natural source, such as Spirulina ( Spirulina ) or Galdieria sulphuraria ( Galdieria sulphuraria ), and can provide color characteristics similar to those provided by the synthetic blue colorant FD&C Blue No. 1.

Described herein are processes and enzymes for the enzymatic production of glucaric acid from glucuronic acid, and more specifically the enzymatic production of substituted glucaric acid from substituted glucuronic acid. Advantageously, the process and enzymes described herein make preferential use substituted glucuronic acid obtained from natural sources, such as underutilized hemicellulose stream from wood and agricultural biorefineries, to produce substantially enantiomerically pure substituted D-glucaric acid.

Provided herein is a composition of substances preferably obtained from natural sources, which is effective in preventing and / or treating iron deficiency conditions or diseases. The composition includes iron pyrophosphate, phosphatidylserine, phosphatidylcholine and starch, preferably acetylated pregelatinised starch. The formulation gives the composition gastro-resistance properties and high bioavailability of the active ingredient iron pyrophosphate. The composition is prepared in the form of a solid, semi-solid or liquid pharmaceutical dosage, preferably for oral administration.

This invention discloses a method for preparing a strain of Lactobacillus saccharidus and its application in the preservation of chilled fresh meat, including the following steps: Step (1) Initial screening: Take 1.0 g of environmental sample, add 9 mL of sterile physiological saline, shake at 37℃ and 200 r / min for 30 min, sonicate for 10 min, then serially dilute to 10⁻⁴-10⁻⁶, take 100 μL and spread it on MRS solid medium, incubate at 37℃ for 48 h, pick single colonies and purify 3 times; Step (2) Antibacterial screening: Use 8 strains of putrefactive bacteria such as Enterobacter and Escherichia coli as indicator bacteria. The preparation method of this Lactobacillus saccharidus strain is based on natural sources, ensuring high safety and making it a suitable alternative to chemical preservatives. It exhibits significant inhibitory effects on major spoilage bacteria (such as Pseudomonas and Enterobacteriaceae) and pathogenic bacteria in chilled meat. Its low-temperature resistance (4℃) and acid and alkali resistance make it suitable for the storage environment of chilled meat. After application, it can reduce the total bacterial count, TVB-N content, pH value, and drip loss rate, delay color changes, and effectively extend the shelf life of chilled meat.

The application belongs to the field of agricultural chemistry, and particularly relates to synthesis and application of a biological activator based on structural modification of L-phenylalanine. The application takes L-phenylalanine as a core raw material, which is rich in natural sources, cheap and easy to obtain, and has good biocompatibility. The structural directional modification is completed through one-step efficient esterification reaction, and the target compound 2-(diethylamino) ethyl-L-phenylalanine ester is successfully synthesized. The compound can effectively improve the germination rate of crops at a low concentration, significantly promote the healthy growth of roots and stems, and enhance the stress resistance of seedlings, and solves the pain point of traditional products "high concentration dependence". In addition, the compound also has outstanding industrialization advantages: the production process is extremely simple, the raw material cost is controllable, the water solubility is excellent, and the compound can be mass-produced without complex post-treatment, which provides a new path for the development of green and environmentally friendly plant growth activators, and has important agricultural application value and ecological significance.

The present invention relates to a novel process for crosslinking polysaccharides of natural origin in aqueous-organic media and detergent formulations comprising the same. The process of the present invention produces gels of natural origin polymers more concentrated or free of added water and in powder form.

This invention belongs to the field of food packaging materials technology and discloses a pH-responsive food spoilage indicator film based on carboxymethyl chitosan and sodium alginate, and its preparation method. This invention provides a smart packaging film that integrates pH-responsive color change and active antibacterial functions within a single film layer. The film uses carboxymethyl chitosan and sodium alginate as the composite film-forming substrate, and simultaneously loads anthocyanins as a pH indicator and magnolol as a natural antibacterial agent. This invention is prepared by a casting method, which is simple. The film exhibits sensitive pH-responsive color change capability for amines produced by food spoilage, enabling real-time visual early warning of the spoilage process; simultaneously, magnolol and carboxymethyl chitosan synergistically endow the film with broad-spectrum antibacterial activity, actively extending the shelf life of fresh food. All components of this invention are derived from natural sources and have biodegradable capabilities, providing a simple, functionally integrated, green, and safe smart packaging solution for fresh food.

The present application relates to the use of an antimicrobial composition comprising essentially ingredients of natural origin as a preservative activator in cosmetic products. Due to the selection of the components of this antimicrobial composition, it has very broad compatibility with most formulations of cosmetic products, and may in particular be integrated into these formulations without destabilizing them or having to modify them, while maintaining the transparency of said cosmetic products.

Apparatus for extraction of components from a material of natural origin, such as cannabis sativa. The apparatus comprises an extraction vessel 4 for containing the material of natural origin. The ext

The application belongs to the technical field of biological disease prevention and treatment, and particularly relates to application of wormwood essential oil in prevention and treatment of soft rot of sweet potato. The soft rot of sweet potato is caused by Rhizopus stolonifer. The wormwood essential oil is prepared by using a water vapor distillation method. In view of the broad-spectrum bacteriostasis of the wormwood essential oil, the wormwood essential oil is innovatively used in the prevention and treatment experiment of the soft rot of sweet potato. The preliminary experimental results show that the wormwood essential oil has a good bacteriostatic effect on the pathogenic bacteria Rhizopus stolonifer causing the soft rot of sweet potato. In view of the advantages of the wormwood essential oil such as safety, no pollution and natural source, based on the results, better technical reference and practical significance can be provided for the harvesting and preservation of sweet potato and the postharvest preservation of other crops.