79results about How to "Improve anti-aging effect" patented technology

The invention relates to a ginseng, ganoderma lucidum and red date preparation with anti-oxidation and anti-aging effects and application thereof, and belongs to the field of health-care food, and the preparation comprises a ganoderma lucidum polysaccharide extract, a ginseng extract and a red date polyphenol extract. According to the method, the high-voltage pulsed electric field is combined with the Sevage method to extract the ganoderan, the extraction efficiency and purity can be improved while the biological activity of the ganoderan is maintained, and the method has the advantages of being short in time, low in cost, easy and convenient to operate and the like and is suitable for industrial production. Meanwhile, the synergistic effect of the components is achieved, the optimal anti-oxidation and anti-aging effects are achieved, and the prepared ginseng, lucid ganoderma and red date oral liquid preparation has the excellent anti-oxidation and anti-aging effects.

The invention relates to an anti-aging composition, a skin care product and a preparation method of the anti-aging composition and the skin care product. The anti-aging composition is prepared from the following components in parts by weight: 0.05 to 0.20 part of collagen, 0.05 to 0.20 part of elastin, 0.10 to 3.00 parts of water lily flower extract, 0.50 to 2.20 parts of folium mori extract, 0.50 to 2.40 parts of rhizoma dioscoreae extract and 1 to 10 parts of beta cyclodextrin. Compared with the prior art, the water lily extract, the mulberry leaf extract and even elastin have the capability of scavenging free radicals, and the Chinese yam extract has the capability of activating human body to synthesize collagen, so that the anti-aging effect is very remarkable through the synergistic interaction of the water lily extract, the mulberry leaf extract and even elastin; external supplement of collagen is matched with an internal synthesis effect, so that the collagen accumulation speed in the skin is greatly increased, the number of wrinkles is effectively reduced, and the anti-aging effect is improved.

The invention relates to a skin care composition and application thereof, and belongs to the technical field of cosmetics. The invention provides a skin care composition which comprises ginsenoside RG2 and III-type collagen, the composition can effectively inhibit secretion of metal matrix protease MMP1 and remarkably increase gene expression of the III-type collagen and has a synergistic anti-wrinkle effect, and the ginsenoside RG2 and the III-type collagen used for preparing cosmetics are high in price, so that the skin care composition has a good anti-wrinkle effect. In this way, the usage amount of ginsenoside RG2 and III type collagen can be reduced, and the ginsenoside RG2 and III type collagen can exert equivalent functions under the condition of low usage amount, so that the cost is saved, and meanwhile, a better anti-wrinkle effect can be achieved.

The invention relates to a ginseng and ganoderma lucidum preparation with anti-oxidation and anti-aging effects and application of the ginseng and ganoderma lucidum preparation with the anti-oxidation and anti-aging effects, ginseng and ganoderma lucidum are used as main components, and the ginseng and ganoderma lucidum preparation with the anti-oxidation and anti-aging effects is obtained through a specific preparation technology.

The invention provides collagen tripeptide as well as a preparation method and application thereof, and belongs to the technical field of active peptide. The invention provides a preparation method of collagen tripeptide, which comprises the following steps: carrying out enzymolysis treatment on tilapia scales and high-temperature-resistant protease, then carrying out enzymolysis treatment by using alkaline protease and neutral protease in sequence, filtering enzymatic hydrolysate by using a ceramic membrane and an organic filter membrane in sequence, and intercepting by using a 400Da nanofiltration membrane to obtain collagen tripeptide. The permeate contains active peptide mainly composed of collagen tripeptide. After the permeate is concentrated and dried, the collagen tripeptide powder is detected, and the protein content reaches 96.2%, the GPH content is 3.8%, and the CTP content is 35.09%. The collagen tripeptide powder has better DPPH (1, 1-diphenyl-2-picrylhydrazyl) scavenging activity; the traditional Chinese medicine composition has an obvious ROS removing effect, a beta-galactosidase activity inhibiting effect and a telomerase activity enhancing promoting effect on a hydrogen peroxide induced zebrafish aging model, and shows an obvious anti-aging effect.

The invention belongs to the technical field of cosmetics, and particularly relates to a natural-source composition with a function of inhibiting multiple types of matrix metalloproteinases of skin and application of the natural-source composition. The composition is prepared from the following components: herba cistanche powder, American ginseng powder, a red-knees herb extract and a creeping rostellularia herb extract. The composition has the effects of inhibiting expression of multiple types of matrix metalloproteinases in skin immortalized keratinocytes, improving elastin synthesis and inhibiting elastase decomposition, and has no obvious side effects. The composition disclosed by the invention can be used for preparing various cosmetics, functional foods and health-care products related to skin aging resistance, and has a wide application prospect.

The invention provides a skin care composition containing stem cell extract as well as a preparation method and application of the skin care composition, and belongs to the technical field of cosmetics. The method comprises the following steps: mixing and culturing the extracted urine-derived stem cells and pilose antler stem cells in a DMEM culture medium added with epidermal growth factors, cholera toxin, penicillin, streptomycin, transferrin, IL-2 and IL-15, then separating a culture solution to obtain mixed exosomes, mixed stem cells and extracellular matrixes, preparing the mixed stem cells into stem cell lipidosome, and preparing the stem cell lipidosome. Embedding the stem cell extract and the mixed exosome into titanium dioxide / silicon dioxide microspheres, adding into an extracellular matrix, and uniformly dispersing to obtain the skin care composition containing the stem cell extract. The skin care composition containing the stem cell extract prepared by the invention can obviously prolong the preservation period of stem cells and exosomes and improve the repair and improvement of the stem cells and the exosomes on skin, and the prepared composition has better effects of resisting aging, whitening, promoting skin elasticity, resisting wrinkles and the like, and has a wide application prospect.

The invention relates to an anti-aging composition containing recombinant collagen and a preparation method thereof. The main component of the composition is high-purity collagen obtained through a gene recombination technology, and various anti-aging active components such as sodium hyaluronate, vitamin C, coenzyme Q10 and vitamin E are combined. The invention also provides a preparation method, which ensures that each component is uniformly distributed and the biological activity is not damaged through low-temperature homogenization treatment and accurate proportioning. The composition disclosed by the invention can be used for remarkably promoting the proliferation of human skin fibroblasts and enhancing the expression of I-type collagen genes, and has a remarkable anti-aging effect. The composition is high in safety and remarkable in effect, is suitable for preventing and treating skin aging, and is widely applied to the fields of medicines and cosmetics.

The present application provides a rhodiolide composition with a core-shell-shell structure, a preparation method thereof comprising the steps of: 1) EGCG inclusion: adding beta-cyclodextrin and EGCG into water, ultrasonic, forming an inclusion compound; 2) liposome assembly: weighing soybean phospholipid and cholesterol, dissolving in chloroform to form a uniform solution; weighing rhodiolide, dissolving in the uniform solution, rotary evaporation to remove chloroform, then adding the inclusion compound and PBS buffer into the container, hydrating, forming a liposome wrapping rhodiolide and inclusion compound; 3) shell loading: weighing collagen, mixing with chitosan solution uniformly to form a complex; adding the complex into the liposome, the complex is coated on the outer layer of the liposome, centrifugal purification, obtaining a rhodiolide composition with a core-shell-shell structure. The present application belongs to the technical field of cosmetic raw materials, and the rhodiolide composition provided has the advantages of high stability, good transdermal effect, and significant anti-aging effect.

The invention discloses an intelligent DYG selenoprotein NMN composite gradient anti-aging supplement product and an intelligent wearable equipment health management system, and a comprehensive and scientific anti-aging and intelligent health management system is constructed by integrating DYG selenoprotein, NMN and other core anti-aging components, combining various nutrients and traditional Chinese medicine components and integrating the traditional Chinese medicine massage and movement concepts. According to the scheme, through the synergistic effect of the composite components, the antioxidant capacity of the body is remarkably enhanced, damage of free radicals to cells is effectively reduced, and therefore the senescence process is delayed. Meanwhile, the application of the intelligent wearable device enables health management to be more personalized and accurate, and customized anti-aging strategies and health suggestions are provided by monitoring user health data in real time. In addition, health and longevity are promoted through multiple ways of adjusting energy metabolism, improving cardiovascular health, enhancing immunity and the like, and the life quality of the user is comprehensively improved. The combination of traditional Chinese medicine massage and exercise is not only beneficial to body health, but also capable of relieving psychological pressure and improving the overall happiness. On the whole, the anti-aging effect is remarkably improved, the disease prevention ability of the user is enhanced, and the healthy, longevity and vigor life experience is brought to the user.

The invention relates to the technical field of amino acid compositions, and discloses a compound amino acid composition for enhancing telomerase activity, which comprises the following components (by weight): 20-25 parts of L-arginine; 15 to 20 parts of L-lysine; 25 to 30 parts of L-glutamine; 10 to 15 parts of L-serine; 5 to 8 parts of L-glycine; 3 to 5 parts of L-proline; 2 to 4 parts of N-acetyl-L-cysteine; 1 to 2 parts of L-tryptophan; 1 to 2 parts of beta-alanine; 2 to 3 parts of L-carnitine; 1-2 parts of taurine; through the synergistic effect of multiple mechanisms, the compound amino acid composition not only significantly enhances the telomerase activity (up to 195%), but also can maintain the telomere length, inhibit cell aging and provide antioxidant protection. The comprehensive regulation effect is derived from a unique metabolic network formed among the components, and mutual promotion and regulation are realized. Experimental results show that the long telomere length (8.3 kb vs control group 7.1 kb) can be maintained in 30-day long-term culture.

The invention discloses a lamellar liquid crystal nano composition with multiple anti-aging effects and application thereof, and the lamellar liquid crystal nano composition comprises the following components in percentage by total weight of the composition: 0.1-20% of glycolipid emulsifier; 0.1%-5% of an amino acid emulsifier; 0.1%-5% of retinol and a derivative thereof; 0.01%-5% of a water-soluble active matter; 0.01% to 1% of ceramide NP; 10%-20% of grease; 30%-50% of a polyol; the total percentage is 100%. A biological surfactant, ceramide and an amino acid surfactant are compounded according to a certain proportion to form a lamellar liquid crystal structure similar to a skin structure.

The invention relates to the technical field of plant extracts, in particular to application of an ensexual euphorbia herb extract in preparation of antioxidant, anti-aging and whitening products. The invention provides an application of a preparation containing at least one of C1-C6 compounds in preparation of antioxidant, whitening and / or anti-aging products. Researches show that the crude extract of the flowers and buds of the euphorbia lasiocarpa, the refined components of the crude extract and the refined components of the euphorbia lasiocarpa and compounds C1-C6 in the crude extract can effectively remove DPPH free radicals, down-regulate expression of senescence-related genes and proteins (such as MMP1 genes and MMP1 proteins), up-regulate expression of anti-aging genes (COL1 genes) and inhibit the activity of tyrosinase, and the euphorbia lasiocarpa has good anti-oxidation, whitening and anti-aging effects, and can be used for preparing the traditional Chinese medicine composition. Wide application prospects are realized in the fields of skin care products, health care products and the like.

The invention relates to the technical field of antioxidant facial masks, in particular to an antioxidant facial mask containing pomegranate extract and a preparation method of the antioxidant facial mask, and the antioxidant facial mask comprises modified facial mask base cloth and facial mask liquid; the preparation method comprises the following steps: stirring and mixing pomegranate peel extract, pomegranate seed extract, sodium hyaluronate, xanthan gum, an emulsifier and deionized water, and sterilizing by utilizing ultraviolet rays to obtain a mixed solution; the modified mask base cloth is sterilized through ultraviolet rays, the sterilized modified mask base cloth is put into a packaging bag, the mixed solution is injected into the packaging bag, and the antioxidant mask containing the pomegranate extract is prepared. The pomegranate peel extract and the pomegranate seed extract are added into the mask liquid, so that the mask has good anti-oxidation and anti-aging effects, the mask liquid is sufficiently loaded through the modified mask base cloth, the mask can release functional substances for a long time, rapid loss of moisture is also avoided, and the quality of the mask is improved.

This invention discloses a fusion protein targeting the urokinase-type plasminogen activator receptor and its application in the field of anti-aging. The fusion protein is composed of a hepatocyte growth factor active domain and a humanized anti-uPAR single-domain antibody linked by a flexible linker peptide, and its specific amino acid sequence is SEQ ID NO:3. This fusion protein can specifically bind to uPAR, which is highly expressed on the surface of senescent cells, with intramolar affinity, achieving targeted delivery of the hepatocyte growth factor active domain. In vitro experiments have demonstrated that this protein can significantly reverse the aging phenotype of human fibroblasts, effectively reduce aging-related β-galactosidase activity, p16INK4a protein expression, and interleukin-6 secretion, and promote cell proliferation. In a rapidly aging mouse model, this protein can systematically improve age-related physiological functional decline. The fusion protein of this invention achieves specific targeting and efficient treatment of senescent cells, providing a new solution for the development of anti-aging drugs.

The invention discloses an anti-aging collagen enhanced skin care composition, relates to the technical field of skin care, and adopts the technical scheme that the composition comprises a core effective component and an auxiliary component, the core component comprises resveratrol and sophoricoside, and the auxiliary component comprises an auxiliary component and an auxiliary component; the auxiliary components comprise active collagen, hyaluronic acid, trehalose, vitamin C or a derivative thereof, phenoxyethanol, carbomer, an emulsifier, glycerol and the balance of pure water. By using the specific emulsifier and accurately controlling the pH value, the stability of resveratrol and sophoricoside and the absorption rate of resveratrol and sophoricoside on skin are remarkably improved; the active ingredients can more effectively permeate into the deep layer of the skin, and the anti-aging effect is achieved. Through scientific proportioning of the two components, the synergistic effect is optimized, the anti-oxidation and anti-inflammatory efficacy is remarkably improved, the capacity of the formula for resisting external environment pressure is enhanced, and skin aging is effectively delayed. The optimized auxiliary components improve the moisture retention and skin feeling of the product, so that the emulsion is easy to absorb.

The present invention relates to a preparation method of a white thorn flower seed extract, and its product and application. The preparation method comprises the following steps: subjecting crushed and sieved white thorn flower seeds to ultrasonic-assisted enzymolysis to obtain an enzymolysis product; subjecting the enzymolysis product to subcritical extraction with subcritical water to obtain an extract; filtering and concentrating the extract to obtain a white thorn flower seed crude extract; subjecting the white thorn flower seed crude extract to flocculation and decolorization to obtain the white thorn flower seed extract. The present invention adopts ultrasonic-assisted enzymolysis and subcritical water extraction technology, and further purifies by flocculation and decolorization, so as to obtain a white thorn flower seed extract rich in polysaccharides and oxymatrine, and no organic solvent or toxic and harmful chemical substances are used in the preparation process, and the white thorn flower seed extract is green and environmentally friendly, and the obtained white thorn flower seed extract is safe and non-irritating, has clear biological activity, and can be applied to the field of skin care products to achieve industrial production.

The present invention relates to the field of cosmetic technology, and in particular to a cosmetic composition and its application in the preparation of skin care products. The invention provides a composition of a filtrate of a fermentation product of bifidobacterium / lactobacillus / soybean seed extract and a microcurrent tetrapeptide, and the composition has at least one of the following effects: I) anti-oxidation; II) protecting cells; III) regulating the transcription level of related genes; IV) regulating the expression level of related proteins; V) inhibiting aging indicator bacteria. Therefore, the composition can achieve a good anti-aging effect, and there is a synergistic effect between the two components. The composition can be applied to the field of cosmetics, with a wider range of efficacy, especially in the field of beauty and skin care.

The invention provides an anti-aging repairing face cream added with NAD + composition and a preparation process of the anti-aging repairing face cream. The anti-aging repairing face cream is prepared from the following components in parts by weight: 20 to 30 parts of NAD < + > composition, 2 to 6 parts of caprylic / capric triglyceride, 1 to 3 parts of non-ionic surfactant, 1 to 4 parts of emulsifier, 4 to 8 parts of oleic acid / linoleic acid / linolenic acid polyglycerol ester, 1 to 6 parts of dimeric pentaerythritol hexaprylate / hexapric acid ester, 0.1 to 1.5 parts of potassium lauroyl wheat amino acid, 2 to 8 parts of polydimethylsiloxane, 1 to 3 parts of 1, 2-propylene glycol and the balance of water. The invention relates to an environment-friendly plastic which is prepared from the following raw materials in parts by weight: 2 to 6 parts of 1, 2-hexanediol, 1 to 4 parts of polyethylene glycol-8, 2 to 6 parts of lauroyl lysine, 0.1 to 1 part of p-hydroxyacetophenone, 1 to 4 parts of potassium cetyl phosphate, 0.1 to 1 part of acrylic acid (ester) / C10-30 alkanol acrylate cross-linked polymer, 3 to 9 parts of sodium polyacrylate grafted starch, 0.5 to 2 parts of xanthan gum, 0.1 to 0.5 part of daily essence, 0.01 to 0.1 part of sodium hydroxide and 0.1 to 0.5 part of tetrasodium glutamate diacetate. The face cream prepared by the preparation method disclosed by the invention has the effects of resisting aging, moistening and preserving moisture on facial skin.

The invention relates to the technical field of medical treatment and beauty treatment, in particular to a solution for injection and a preparation method thereof. According to the injection solution disclosed by the invention, the cross-linked sodium hyaluronate, the vitamin B, the active peptide, the nicotinamide, the amino acid, the buffer solution and the water for injection are taken as raw materials, so that the injection solution is endowed with relatively good enzyme stability, is not easy to quickly decompose in vivo and is non-toxic; functional raw materials such as active peptide and nicotinamide are used, so that the injection solution has excellent anti-aging and melanin inhibition effects.

The invention relates to the field of medicine and cosmetology, and discloses a cell active peptide composition for promoting regeneration of multi-type collagen structure protein, a preparation method of the cell active peptide composition and application of the cell active peptide composition in medicine and cosmetology. The composition is prepared from the following raw materials: tripeptide-10 citrulline, hexapeptide-9, hydrolyzed sodium hyaluronate, gamma-aminobutyric acid, decarboxylated carnosine hydrochloride, acetyl tetrapeptide-3, acetyl tetrapeptide-11, palmitoyl dipeptide-7, palmitoyl pentapeptide-4 and the like. The composition can promote the synergistic expression of I-type, III-type, IV-type, VII-type and XVII-type collagen, fibronectin, elastin and glycosaminoglycan of the skin; collagen crosslinking is prevented, a triple-helix structure is maintained, and collagen degradation is inhibited. When being applied to skin medicine and beauty treatment, the composition can accelerate regeneration of structural proteins such as skin collagen, repair skin injury, reduce wrinkles such as crow's feet, lacrimal ducts, nasolabial folds and subocular wrinkles, solve the problem of skin aging caused by loss of the structural proteins such as collagen, and improve skin elasticity and compactness.

The invention discloses an anti-aging water-soluble facial essence block and a preparation, packaging and using method thereof, and relates to the technical field of cosmetics, the anti-aging water-soluble facial essence block is obtained by compounding a filling agent, a humectant, an anti-aging agent, a soothing agent, an anti-allergy agent, a repairing agent, a preservative and a neutralizing agent, and the anti-aging water-soluble facial essence block can improve the anti-aging ability of skin and can also improve the anti-aging effect of the skin. After the traditional Chinese medicine composition is used, the percutaneous water loss rate of the skin of a user can be reduced, the skin barrier can be repaired, and the secondary recurrence of skin problems can be reduced; meanwhile, after the anti-aging water-soluble facial essence block is mixed with water according to a certain proportion, the anti-aging water-soluble facial essence block can be quickly dissolved to form facial essence, the operation is simple, and the use is convenient.

The invention relates to the field of acne-removing products, aims to solve the problem that the acne-removing products are difficult to be suitable for acne types caused by different factors, and provides a traditional Chinese medicine composition for removing acnes, which is prepared from the following components in parts by weight: 80 to 170 parts of bletilla striata, 105 to 210 parts of radix paeoniae rubra, 120 to 265 parts of herba portulacae, 110 to 230 parts of dandelion, 90 to 210 parts of herba violae and 115 to 310 parts of fructus forsythiae. The traditional Chinese medicine composition for removing acnes, provided by the invention, has the effects of clearing away heat and toxic materials, diminishing swelling and removing stasis, resisting bacteria, resisting inflammation and whitening after the six traditional Chinese medicines are combined. Wherein fructus forsythiae is used as a main drug and has the effect of killing propionibacterium acnes, dandelion and herba violae are used as ministerial drugs and have the effects of resisting inflammation and oxidation, purslane is used as an adjuvant drug and has the effects of resisting bacteria, diminishing inflammation, removing cutin and repairing cuticles, and rhizoma bletillae and radix paeoniae rubra are used as conductant drugs and have the effects of resisting oxidative stress and improving blood circulation; the traditional Chinese medicine mask cream provided by the invention can promote the absorption of traditional Chinese medicine components, and also has good moisture retention, film-forming property, aging resistance and the like.

The invention discloses an anti-oxidation skin care product formula capable of diminishing inflammation, relieving itching, moistening skin and delaying senescence, and relates to the technical field of anti-oxidation skin care products. The anti-oxidation skin care product formula comprises the following raw materials: a purslane extract, alum, purified water, glycerol, coconut oil, stearic acid, triethanolamine, methylparaben, plant essential oil, vitamins, beewax, sodium carboxymethyl cellulose and titanium dioxide, the purslane extract has good anti-inflammatory, anti-oxidation and antibacterial effects, is helpful for relieving skin inflammation, reducing redness, swelling and irritation, and has a good anti-inflammatory, anti-oxidation and antibacterial effect. The anti-oxidation skin care product has obvious effects of resisting oxidation, delaying senescence and moistening skin and beautifying, alum has astringing and antibacterial characteristics, is beneficial to reducing skin grease secretion and astringing pores, also has a certain antibacterial effect and can kill parasites to relieve itching, and after being used, the anti-oxidation skin care product can relieve skin inflammation, reduce redness and swelling and irritation, moisten skin, preserve moisture and resist oxidation, and can be used as an anti-oxidation skin care product. The skin aging is delayed.

The invention relates to the technical field of senescence delaying medicines, and discloses a senescence delaying preparation which comprises the following components: resveratrol, dihydroquercetin, curcumin, coenzyme Q10, bromelain, glutathione, roxburgh rose SOD and nicotinamide ribose NR. A preparation method of the preparation capable of delaying senescence comprises the following steps: step 1, weighing the resveratrol, the dihydroquercetin, the curcumin, the coenzyme Q10, the bromelain, the glutathione, the roxburgh rose SOD and the nicotinamide ribose NR in parts by weight for later use; and 2, mixing the raw materials, and further grinding. Compared with the prior art, the invention has the following advantages: experiments prove that after the product is taken for 10 weeks, the human body is kept in a vigorous state, vigorous energy, full brain and relatively vigorous state, age pigments and pigmented spots are gradually eliminated, the skin is in a whitening state, the immune function of the human body can be improved, and an excellent anti-aging effect can be shown.

The invention discloses a rosa roxburghii tratt ergothioneine fermentation broth and a preparation method and application thereof. The preparation method comprises the following steps: inoculating a fermentation substrate with lactobacillus A, carrying out primary fermentation to obtain a primary fermentation broth, adding ergothioneine into the primary fermentation broth, inoculating lactobacillus B, and carrying out secondary fermentation and sterilization to obtain the rosa roxburghii tratt ergothioneine fermentation broth. Wherein the fermentation substrate comprises roxburgh rose and water; the lactobacillus A comprises lactobacillus delbrueckii subsp. Bulgaricus, and the lactobacillus B comprises lactobacillus plantarum. According to the method, the active substances in the roxburgh rose are released in the primary fermentation process by utilizing the composite strains in a staged fermentation manner, the ergothioneine is added in the secondary fermentation process, a synergistic effect is realized in the mixed fermentation process, the whole fermentation process performs staged fermentation on the ergothioneine and the roxburgh rose, the release of the active substances in the roxburgh rose is improved, and the yield of the roxburgh rose is improved. Ideal effects of resisting aging, resisting oxidation, promoting cell repair, preserving moisture and the like are achieved.

The invention relates to the technical field of functional compositions, in particular to an anti-wrinkle and firming functional composition containing glassine as well as a preparation method and application of the anti-wrinkle and firming functional composition containing glassine. The composition containing the botryine and having the anti-wrinkle and firming effects is prepared from the following components: 3 to 15 parts of an RS configuration botryine solution, 1 to 3 parts of a spherical PDRN compound, 0.1 to 0.5 part of a folium achilleae millefolium extract wrapped by maltodextrin and 0.5 to 1.25 parts of a sodium mannose phosphate solution, the RS-configuration glassine solution comprises R-type glassine and S-type glassine in a mass ratio of (7-8): (2-3); the spherical PDRN compound is prepared from poly (deoxyribonucleotide) (PDRN), hydrolyzed sodium hyaluronate, 1, 2-pentanediol, 1, 2-hexanediol and deionized water; the sodium mannose phosphate solution comprises sodium mannose phosphate, glycerol and water. Through the multi-target multi-layer synergistic effect of all the components, the obvious tightening and wrinkle fading effects superior to those of a single component or a conventional compound are obtained.

The invention relates to the technical field of skin care product raw materials, and particularly discloses an anti-aging composition and a preparation method thereof, the anti-aging composition comprises the following components by mass: 9-10 parts of a composite extract; 4.7 to 5.3 parts of a cell metabolism activator; 0.9 to 1.1 parts of a preservative; 84.6 to 86.4 parts of a solvent; the composite extract is prepared by compounding a dendrobium officinale stem extract, a snow lotus herb extract, a cistanche deserticola extract and a ganoderma spore extract. The anti-aging tea has the advantage of having a better anti-aging effect.

The present invention relates to the technical field of cosmetics, and discloses a composition having the effect of promoting the expression of antioxidant enzymes and its application. The composition having the effect of promoting the expression of antioxidant enzymes provided by the present invention comprises a turmeric root extract and dimethylmethoxychromanol, wherein the mass ratio of the turmeric root extract to the dimethylmethoxychromanol is (0.5-3):1. The present invention adopts turmeric root extract and dimethylmethoxychromanol to mix according to the mass ratio, and achieves a synergistic effect in promoting the expression of antioxidant enzymes. The composition having the effect of promoting the expression of antioxidant enzymes provided by the present invention is applied to cosmetics and / or skin care products, which can exert obvious skin antioxidant and anti-aging effects at a lower application amount.

The invention discloses a preparation method of hypertonic stimulated bone marrow mesenchymal stem cells, and particularly relates to the technical field of stem cell culture. The method comprises the following steps: S1, adding a sodium chloride solution into a DMEM / f-12 complete medium to prepare a hypertonic medium system; s2, selecting third-generation bone marrow mesenchymal stem cells, and replacing the hypertonic culture medium when the cells are fused to 70-80%; s3, after the culture medium is replaced, culturing in a constant-temperature cell culture box to obtain the bone marrow mesenchymal stem cells subjected to hypertonic stimulation treatment. The method can effectively improve the cell activity and multiplication capacity of the bone marrow mesenchymal stem cells, delay cell senescence and enhance the anti-active oxygen and anti-hypertonic capacity, thereby improving the treatment effect on the radiation-induced lung injury.