666 results about "Lactobacillus acidophilus" patented technology

The invention relates to the technical field of biological pharmacy, and discloses a probiotic microcapsule with a function of improving intestinal microecology, which comprises the following components in percentage by weight: lactobacillus rhamnosus: each gram of formula contains 1010 CFU of lactobacillus rhamnosus; lactobacillus acidophilus: each gram of the formula contains 109 CFU; clostridium butyricum: each gram of the formula contains 108 CFU; 5%-8% of a nano sodium alginate-chitosan compound; 3%-5% of peptide nanoparticles; 2%-4% of a natural polymer intelligent response film; 3%-6% of arabinoxylan oligosaccharide; 4%-7% of resistant dextran; 2%-4% of lentinan; and 0.1%-0.3% of resveratrol. Through a double-layer or three-layer embedding technology of the nano sodium alginate-chitosan compound and the intelligent response polymer film, the tolerance of the probiotics in gastric acid and cholate environments is remarkably enhanced, and targeted release of the probiotics in small intestines and colon is ensured.

The invention relates to a composite metabiotic inoculant for promoting vaginal micro-ecological balance and application thereof. Strain in the composite metabiotic inoculant for promoting vaginal micro-ecological balance comprises an inactivated LA88 strain and an inactivated N13 strain. The invention develops a brand-new probiotic intervention strategy for promoting the micro-ecological balance of the vagina, namely, the inactivated lactobacillus acidophilus LA88 strain and the inactivated lactobacillus plantarum N13 strain are compounded to form a brand-new composite metabiotic bacterial agent, and the composite metabiotic bacterial agent has a relatively good proliferation effect on various beneficial bacteria of the vagina, and can be used for preparing the probiotics for promoting the micro-ecological balance of the vagina. The traditional Chinese medicine composition has a strong inhibition effect on various vaginal pathogenic bacteria, and can promote recovery of a healthy microbial community structure.

The invention relates to a weight-losing enzyme and a preparation method thereof, and belongs to the technical field of biology, and the weight-losing enzyme comprises a fruit enzyme, a vegetable enzyme, a seed enzyme and a lotus leaf extract; the fruit enzyme is obtained by performing enzymolysis on mixed fruit pulp of apples, lemons, grapefruits and haws through pectinase, performing enzymolysis through pepsase and performing co-fermentation through bifidobacterium longum and lactobacillus acidophilus; the vegetable enzyme is obtained by performing enzymolysis on mixed vegetable pulp of wax gourd pulp, celery and spinach through pectinase, performing enzymolysis through pepsin and performing fermentation through lactobacillus plantarum and bifidobacterium adolescentis; the seed enzyme is obtained by carrying out trypsin enzymolysis on mixed powder of semen raphani and phaseolus calcaratus, then carrying out nattokinase enzymolysis and then fermenting with bifidobacterium breve; the lotus leaf extract is obtained by sequentially carrying out enzymolysis on lotus leaves through hemicellulase, snail protease and nattokinase. All the components are matched for use, so that the weight-losing food has the effects of promoting digestion, inhibiting fat absorption, regulating intestinal flora, promoting metabolism and the like, and has a good weight-losing effect.

The invention relates to the technical field of health care products, and discloses kidney function health wine based on traditional Chinese medicine fermentation and a preparation method of the kidney function health wine. 6-10 parts of cistanche deserticola; 9-30 parts of radix astragali and 6-12 parts of fructus lycii; the fermentation strain comprises lactobacillus acidophilus, lactobacillus plantarum, bifidobacterium longum subsp. Longum, saccharomyces cerevisiae and bacillus subtilis, and the fermentation strain comprises the following strains: lactobacillus acidophilus JYLC-374, lactobacillus plantarum JYLC-482, bifidobacterium longum subsp. Longum JYBB-163, saccharomyces cerevisiae JYSC-710 and bacillus subtilis JYBS-312. By adopting the technical scheme that a traditional Chinese medicine compound formula is combined with specific probiotic fermentation, the technical effects of enhancing the bioavailability of active ingredients and promoting kidney function regulation are achieved, and the dissolution rate and the biotransformation rate of herbal medicine active substances are improved.

The invention relates to the technical field of pharmaceutical preparations, and discloses a composition with liver protection and antioxidation effects and a preparation method thereof.The composition is prepared from galactosamine modified astragalus membranaceus exosome, schisandra chinensis nanocrystals, liquorice-chitosan nanoparticles, lactobacillus acidophilus freeze-dried powder, beta-(1, 3) / (1, 3, 4-tetramethyl-1, 3-pentanediol monoisobutyrate) sourced from saccharomyces cerevisiae, and beta-(1, 3, 4-tetramethyl-1, 3-pentanediol monoisobutyrate). And (6) a dextran, grape exosome-curcumin hybrid vesicle freeze-dried powder, a curcumin-mitochondrial targeting peptide compound, a resveratrol-hydroxypropyl-beta-cyclodextrin inclusion compound and reduced panthenol. According to the liver-protecting and anti-oxidation composition disclosed by the invention, multi-dimensional intervention on liver protection is realized through an elaborately designed ternary system. The system is composed of a traditional Chinese medicine extract, a microorganism-plant exosome combination and a high-bioavailability antioxidant, all the parts have a synergistic effect, and the liver protection effect is remarkably improved.

The invention belongs to the technical field of microorganisms, and particularly relates to a postbiotic preparation for pets as well as a preparation method and application of the postbiotic preparation. The metabolite preparation provided by the invention comprises a lactobacillus plantarum Ps-8 inactivated thallus and a metabolite thereof, a lactobacillus casei C-9 inactivated thallus and a metabolite thereof, a bifidobacterium animalis subsp. Lactis BB-16 inactivated thallus and a metabolite thereof, and a lactobacillus acidophilus LA-14 inactivated thallus and a metabolite thereof. The pet food can be applied to various food types of different varieties of cat and dog pets, and has the effects of improving the intestinal barrier function of the pets, enhancing the immunity, reducing the incidence rate of diarrhea, reducing the food change stress, promoting the digestion of nutrient substances, optimizing the state of spirit and fur, reducing the odor of excrement, fading the odor of the oral cavity, improving the health level of the oral cavity and teeth and the like.

The invention relates to the field of microorganisms, and discloses a strain of lactobacillus acidophilus and application of the lactobacillus acidophilus in preparation of drugs for preventing and / or treating hyperlipidemia and hyperglycemia, the preservation number of the lactobacillus acidophilus is CGMCC No.33155, the strain can generate lactic acid, is resistant to acid and cholate, and has strong self-aggregation ability and hydrophobic ability. The strain provided by the invention can promote the decomposition of fat and sugar by degrading cholesterol and inhibiting the activity of alpha-glucosidase and alpha-amylase, can reduce the expression levels of blood sugar, blood fat and inflammatory factors of hyperlipidemia and hyperglycemia mice, and provides a new idea for preparing medicines for preventing and / or treating hyperglycemia and hyperlipidemia.

The invention provides composite probiotic powder capable of nourishing the stomach and tonifying the spleen and a preparation method of the composite probiotic powder. The composite probiotic powder comprises the following components in parts by weight: 6-12 parts of freeze-dried bacterial powder, 40-50 parts of prebiotics, 20-25 parts of fruit and vegetable powder, 14-19 parts of enzymolysis plant powder, 12-15 parts of fermented plant powder and 46-61 parts of sugar alcohol. The freeze-dried bacterial powder is prepared by mixing lactobacillus acidophilus, bifidobacterium animalis, lactobacillus plantarum, lactobacillus helveticus and lactobacillus bulgaricus; the prebiotics are prepared by mixing inulin, galactooligosaccharide, isomaltooligosaccharide and fructo-oligosaccharide in a weight ratio of 10: (8-12): (4-6): (13-16). The prepared compound probiotic powder has the effects of nourishing the stomach and tonifying the spleen.

The invention relates to the technical field of food, and particularly discloses a compound prebiotics embedded probiotic microcapsule and a preparation method and application thereof.The green tea leaves serve as main raw materials, water extraction is conducted on the green tea leaves, meanwhile, ultrasonic-assisted treatment is adopted, active ingredients in the green tea leaves can be more effectively released, the extraction time is shortened, and the content of probiotics in the green tea leaves is increased; the extraction rate of active ingredients in the green tea leaves is improved; then, lactobacillus acidophilus is adopted to ferment the extract liquid, so that the green tea fermentation liquid contains more antioxidant active ingredients, combined polyphenol in the extract liquid can release micromolecular polyphenol in the fermentation process, the content of substances such as flavone and polyphenol in the green tea fermentation liquid is increased, and the antioxidant activity is further improved; and then the modified dietary fiber is used as a main wall material of the microcapsule to embed the green tea fermentation liquor and the probiotics, so that the stability of active substances and the probiotics in the green tea fermentation liquor is improved, and the green tea fermentation liquor can play a role in protection and slow release in the simulated digestion process.

The invention discloses a composition for treating insomnia. Comprising probiotic compounds: lactobacillus plantarum, bifidobacterium lactis, lactobacillus crispatus, lactobacillus acidophilus, lactobacillus rhamnosus, bifidobacterium bifidum, lactobacillus reuteri, lactobacillus casei, lactobacillus bulgaricus, lactobacillus fermentum, lactobacillus gasseri, lactococcus lactis, bifidobacterium longum, lactobacillus salivarius, bifidobacterium breve, streptococcus thermophilus and lactobacillus paracasei; lactobacillus helveticus; and traditional Chinese medicine components and prebiotics. Probiotics are matched with traditional Chinese medicines with homology of medicine and food, and corresponding prebiotics are supplemented, so that the balance of intestinal flora can be adjusted and information transmission between intestines and cranial nerves can be promoted through the synergistic effect of the probiotics and the corresponding prebiotics, and then gastrointestinal inflammation, ulcer, helicobacter pylori infection, constipation and insomnia are treated or improved; and treating or improving spleen and stomach disharmony, liver qi stagnation, excessive heart fire, fire excess from yin deficiency, heart-kidney disharmony caused by emotion, pressure, diseases and the like, and insomnia caused by the symptoms.

The invention relates to the technical field of functional beverage processing, in particular to a method for preparing ginger black tea by combining fresh ginger pretreatment with black tea probiotic fermentation, a ginger black tea product and application of the ginger black tea product. The method comprises the following steps: a) fresh ginger enzymolysis pretreatment: fresh ginger is subjected to enzymolysis treatment to reduce the gingerol content; b) microencapsulation of gingerol: preparing the ginger liquid subjected to enzymolysis, sodium alginate and chitosan into microcapsules; c) black tea extraction: performing water extraction on black tea to prepare black tea liquid; d) probiotic activation: carrying out activation culture on lactobacillus acidophilus and lactobacillus plantarum; e) performing multi-stage fermentation: mixing the black tea liquid, gingerol microcapsules and activated probiotics, and performing fermentation through multi-stage temperature and pH control; (f) post-processing the product, namely post-processing the fermentation liquor to obtain the probiotic-containing ginger black tea product, so that the effective components of the ginger are reserved while the content of spicy components of the ginger is reduced.

The invention relates to the field of biotechnology and female health care, in particular to a stachyose composition for promoting micro-ecological regulation of lactobacillus and application of the stachyose composition, and the composition comprises stachyose and pharmaceutically acceptable auxiliary materials. The stachyose is used as prebiotics to selectively promote proliferation and colonization of the lactobacillus crispatus, the combination of 1%-5% of the stachyose and 0.1%-0.5% of the lactic acid can promote proliferation of the lactobacillus crispatus, the lactobacillus crispatus is one or more of the lactobacillus crispatus, the lactobacillus plantarum and the lactobacillus acidophilus, and the combination of 1%-5% of the stachyose and 0.1%-0.5% of the lactic acid can inhibit gardnerella and candida albicans. The stachyose composition disclosed by the invention is in the form of slow-release gel and bath foam; the composition can be used for treating or preventing bacterial vaginitis, colpitis mycotica and related symptoms, has the advantages of no antibiotics, no drug resistance, high safety and the like, and is suitable for the fields of vagina local nursing and micro-ecological regulation.

The invention discloses a functional probiotic composition and application thereof, and relates to the technical field of microbial engineering. Bifidobacterium longum, lactobacillus acidophilus and enterococcus faecalis are combined to serve as a microbial agent, the microbial agent and active substances of the tea leaves form a composition, then the composition is combined with prebiotics, it is ensured that viable bacteria directly reach the intestinal tract through a microencapsulation technology, and the effect of improving the immune function is achieved; tea polyphenol in the active substances of the tea leaves can serve as a carbon source of prebiotics to stimulate proliferation of the bifidobacterium longum and the lactobacillus acidophilus, so that the acid resistance and intestinal colonization capacity of the microbial inoculum are enhanced, and meanwhile, theanine in the active substances of the tea leaves, the bifidobacterium longum and the lactobacillus acidophilus synergistically promote secretion of gamma-aminobutyric acid, so that the effect of improving the intestinal colonization is achieved. And the tea polyphenol can inhibit the large intestine rod from adhering to the intestinal mucosa, and the probiotic agent secretes antibacterial peptide, so that the integrity of the intestinal barrier is maintained together.

The present invention relates to a composite postbiotic agent for promoting vaginal microecological balance and its application, wherein the strains in the composite postbiotic agent for promoting vaginal microecological balance include inactivated LA88 strain and inactivated N13 strain. The present invention has developed a new probiotic intervention strategy for promoting vaginal microecological balance, that is, inactivating Lactobacillus acidophilus Lactobacillus acidophilus LA88 strain and inactivated Lactobacillus plantarum Lactobacillus plantarum The N13 strain is compounded to form a new composite postbiotic agent, which has a good proliferation effect on a variety of beneficial vaginal bacteria, a strong inhibitory effect on a variety of vaginal pathogenic bacteria, and can promote the restoration of a healthy microbial community structure.

The invention discloses a composite microbial preparation for treating obesity of pet dogs and application of the composite microbial preparation, and belongs to the technical field of microbial preparations. The compound microbial preparation is prepared by fermenting lactobacillus acidophilus L100 and lactobacillus reuteri GBW1146, and the preservation number of the lactobacillus reuteri GBW1146 is CGMCC (China General Microbiological Culture Collection Center) No. 34455. The compound microbial preparation is prepared by fermenting lactobacillus acidophilus L100 and lactobacillus reuteri GBW1146. The compound microbial preparation can remarkably reduce digestion and absorption of intestinal tracts of dogs on fat and reduce triglyceride and cholesterol levels in blood, so that the average food intake and average calorie consumption of the dogs are reduced, and finally the effect of reducing obesity of the pets is achieved. The compound microbial preparation provided by the invention enhances the competitiveness of the pet feed additive and series products thereof in China in the international market, and has a wide application prospect.

The invention belongs to the technical field of traditional Chinese medicine patches, mainly relates to a traditional Chinese medicine patch and a preparation method thereof, and in particular relates to a patch for treating cough and asthma and a preparation process thereof. Natural plants including the semen brassicae, the pink reineckea herb and the modified herba ephedrae are selected, the performance is improved through synergistic fermentation of the lactobacillus acidophilus CICC-22162 and the bifidobacterium breve CICC-6184, the effect of treating cough and asthma of the traditional Chinese medicine is improved, meanwhile, under the fermentation condition, the effect of treating diarrhea is achieved under the synergistic effect of leavening of the semen brassicae and the pink reineckea herb, and the traditional Chinese medicine composition has a good application prospect. In addition, the perillaseed extracting solution and the asarum extracting solution which are used in the patch have extremely high oxidation resistance under the synergistic effect, so that the stability of the patch is effectively improved, and the shelf life of the patch is prolonged.

The invention relates to a probiotic agent capable of resisting helicobacter pylori infection and application of the probiotic agent. The bacterial strains in the probiotic agent capable of resisting helicobacter pylori infection are composed of a Bifidobacterium animalis subsp. Lactis (Bifidobacterium animalis subsp. Lactis). Lactis BLa80 bacterial strain and a Lactobacillus acidophilus LA18 bacterial strain. The invention further relates to a preparation method of the probiotic agent capable of resisting helicobacter pylori infection and application of the probiotic agent capable of resisting helicobacter pylori infection. The two strains can cooperate with each other and promote each other, and have a synergistic effect in the aspect of resisting helicobacter pylori infection, specifically, the level of an Hp-IgG antibody and the level of endotoxin of a mouse infected with helicobacter pylori are remarkably reduced; the levels of serum inflammatory factors such as IL-17A, IL-10, IL-23, IFN-beta and IFN-gamma of mice infected with helicobacter pylori are regulated, and inflammatory response caused by helicobacter pylori infection is inhibited; the activity of pepsin, the activity of cellulase and the activity of alpha-amylase are obviously improved, so that the digestive ability of the stomach is enhanced.

The invention relates to a skin-cleaning composition and application thereof in cleaning cream, and belongs to the technical field of daily chemicals, the skin-cleaning composition comprises the following raw materials: plant fermentation liquor, a chrysanthemum artemisia extract, silk amino acid, cetyl alcohol ethyl hexanoate, PEG-20 glyceryl triisostearate and soapberry seed oil; the preparation method of the plant fermentation liquid comprises the following steps: S1, pretreating part of the raw materials; s2, activating and culturing the strain; and S3, adjusting the pH value of the mixed solution A, performing temperature-controlled sterilization, cooling, adding mannase, performing temperature-controlled enzymolysis, performing enzyme deactivation after enzymolysis is completed, so as to obtain a mixed solution B, cooling, adding a lactobacillus acidophilus fermentation seed solution and a streptococcus thermophilus fermentation seed solution, performing temperature-controlled standing fermentation, performing temperature-controlled sterilization and speed-controlled centrifugation after fermentation is completed, taking supernate, and performing 0.22 mu m membrane microfiltration, so as to obtain the plant fermentation liquor. The raw materials of the skin-cleaning composition provided by the invention have a synergistic effect, so that the skin-cleaning composition has the effects of moisturizing and whitening while effectively cleaning the skin.

The invention belongs to the technical field of cosmetic raw materials, and particularly provides a composition containing kava pepper and mung bean seed extracts, a preparation method and application. The preparation method of the mung bean seed extract is specifically optimized, for example, a lactobacillus plantarum strain, a lactobacillus johnsonii strain and a lactobacillus acidophilus strain are compounded and used for fermenting sprouted mung bean liquid, and a fermentation culture medium, fermentation environment conditions and the like are optimized; the nutritional ingredients of protein, glycine, inorganic salt and the like in the prepared mung bean seed extract are effectively improved, so that the prepared composition containing the kava pepper and the mung bean seed extract and the cosmetics thereof can show excellent effects of moisturizing and repairing, resisting inflammation, resisting aging, instantly calming, easing pain and the like.

The invention belongs to the technical field of probiotic particles, and particularly relates to probiotic particles for improving intestinal functions as well as a preparation method and application of the probiotic particles. The probiotic particles capable of improving the intestinal function comprise a probiotic core, a first embedding layer, a second embedding layer and a third embedding layer, the probiotic inner core is prepared from plant lactobacillus, bifidobacterium animalis, lactobacillus acidophilus, bifidobacterium longum, lactobacillus paracasei, lactobacillus rhamnosus, lactobacillus fermentum, lactobacillus helveticus, streptococcus thermophilus, plant lactobacillus, lactobacillus helveticus and lactobacillus rhamnosus. According to the present invention, the twelve probiotics are contained, and the latest three-layer embedding technology is adopted so as to enhance the storage property and the digestive tract tolerance, such that the product can maintain the beneficial bacterium activity for a long time without refrigeration, and the product is suitable for the crowd with the alteration of the intestinal flora.

The invention provides a lactobacillus acidophilus HX-LA15 with strong antioxidant activity, the preservation number of the lactobacillus acidophilus HX-LA15 is CGMCC (China General Microbiological Culture Collection Center) No.32954, and the lactobacillus acidophilus HX-LA15 is preserved in China General Microbiological Culture Collection Center on December 23, 2024. Meanwhile, the invention further provides a compound fermentation product of the lemon myrtle leaves and the herba cistanche, a probiotic preparation containing the lactobacillus acidophilus HX-LA15 and the compound fermentation product as well as a preparation method and application of the probiotic preparation. The lactobacillus acidophilus HX-LA15 provided by the invention has a remarkable scavenging capability on free radicals, and compared with other probiotics, the lactobacillus acidophilus HX-LA15 can be used for remarkably increasing the content of cistanoside A and polyphenol compounds in a compound fermentation product after fermenting the lemon myrtle leaves and the cistanche; therefore, the fermented product has the function of improving reproductive function decline and reproductive aging of mice with kidney-yang deficiency, and has a good application prospect.

The invention discloses a method for quantitatively detecting viable bacteria of lactobacillus reuteri, lactobacillus rhamnosus, lactobacillus paracasei and lactobacillus acidophilus. The novel molecular detection target disclosed by the invention has high specificity on target bacteria. The disclosed PMA-qPCR method comprises the steps of target detection, qPCR primer and probe design, qPCR detection system, PMA treatment condition and viable bacteria quantitative standard curve. After qPCR amplification, if a Cq value appears, the dissolution peak is single and the dissolution temperature is consistent with that of a positive sample (only aiming at a dye method), the lactic acid bacteria are identified as target lactic acid bacteria, and the number of viable bacteria can be calculated according to a corresponding standard curve. The method can effectively detect and count viable bacteria of Lactobacillus reuteri, Lactobacillus rhamnosus, Lactobacillus paracasei and Lactobacillus acidophilus, has the advantages of rapidness, accuracy, simple operation and the like, and is convenient for food enterprises and inspection institutions to use.

The invention discloses a Kunlun chrysanthemum bud extract compound with intestinal probiotic and hypoglycemic activity and a preparation method thereof, and belongs to the technical field of natural compound extraction. The preparation method comprises the following steps: firstly, fermenting Kunlun chrysanthemum bud powder by adopting lactobacillus acidophilus, then repeatedly extracting by utilizing a gradient ethanol solvent, and preparing an extract compound by taking water as a solvent, so that the stability of an organic solvent extract in an aqueous solution is remarkably improved; a further research shows that when the absolute ethyl alcohol extract, the water extract and the extract compound of the Kunlun chrysanthemum buds are independently used as prebiotics, intestinal microorganisms can be changed; when being used as an alpha-glucosidase inhibitor, the alpha-glucosidase inhibitor shows in-vitro hypoglycemic activity, however, a compound prepared from absolute ethyl alcohol and a water extract can better play the role, and the compound shows a synergistic effect when playing the role. And a theoretical basis is provided for the application in the fields of prebiotics and blood glucose reduction.

A composition includes postbiotics comprising two or more of the following components: Lactobacillus acidophilus, Lactobacillus rhamnosus, and Saccharomyces boulardii; wherein the postbiotics are dead, whole-cell postbiotics. A method of providing to a subject an immunomodulatory, immune regulatory and / or immune boosting effect through administering the composition is also provided. A method of making the postbiotic composition is also provided.

The invention discloses a microbial compound feed for improving disease resistance of blue crabs and a preparation method of the microbial compound feed, and belongs to the technical field of feed preparation. The microbial compound feed comprises the following raw materials in parts by weight: 30-40 parts of fermented soybean meal, 20-25 parts of bran, 15-20 parts of fish meal, 5-8 parts of a compound microbial agent, 3-5 parts of algal polysaccharides, 2-3 parts of a radix astragali extract, 1-2 parts of chitosan, 2-3 parts of a mineral premix and 1-1.5 parts of compound vitamins, wherein the compound microbial agent comprises bacillus licheniformis, lactobacillus acidophilus and saccharomyces cerevisiae. The microbial compound feed disclosed by the invention comprehensively improves the disease resistance of the blue crabs and improves the survival rate through various ways, such as nutrition balance, immune regulation and intestinal health improvement, so that the breeding cost is reduced, and the income of farmers is increased.

The invention provides a micromolecular renewal fermentation composition and application thereof, and belongs to the technical field of cosmetics. The fermentation composition comprises the following components in parts by weight: 95-99 parts of a composite plant fermentation concentrated solution and 1-5 parts of a protective agent, the compound plant fermentation concentrated solution is prepared by taking a rhizoma polygonati root extract, a poria cocos sclerotium extract, an avocado fruit extract and a ginseng root extract as compound plant raw materials, and fermenting the compound plant raw materials through compound lactobacillus to obtain a secondary metabolite; the composite lactobacillus is composed of at least two of lactobacillus plantarum, lactobacillus mucus fermentation, lactobacillus casei and lactobacillus acidophilus. The fermentation composition is prepared by fermenting multiple plant extracts, the multi-link anti-aging effect is remarkable, skin wrinkles are comprehensively improved through multiple ways of scavenging free radicals, promoting regeneration of type I collagen and elastin, resisting saccharification and the like, the anti-wrinkle and tightening effects are good, the good anti-inflammatory and soothing effects are achieved, safety is good, and the composition is suitable for being used for skin care. The application prospect in the field of beauty makeup or daily chemicals is wide.

The present application belongs to the technical field of biological fermentation, and discloses a natural plant fermentation liquor, which is prepared from acanthopanax, angelica sinensis, rosa davurica, phellinus baumii, tea leaves, water, mixed enzymes and mixed bacterial agents; wherein the mixed enzymes include cellulase, pectinase and tannase, and the mixed bacterial agents include lactobacillus plantarum, schizosaccharomyces and lactobacillus acidophilus.The natural plant fermentation liquor has high safety, good clarity after adjusting the concentration of crude drugs, and can be added into a cosmetic matrix.The preparation method is simple, and the effective active ingredients of the natural plants and tea leaves are extracted by the synergistic effect of bacteria and enzymes to the maximum extent.In addition, the present application also discloses the application of the natural plant fermentation liquor in preparing cosmetics for treating oily sensitive skin.

The present invention relates to a prebiotic feed additive for promoting intestinal health of pigs, belonging to the technical field of feed, the prebiotic feed additive of the present invention comprises prebiotic components and biological adjuvants, the prebiotic components comprise oligofructose, oligoisomaltose, inulin and resistant dextrin, the biological adjuvant is a product obtained by co-enzymatic hydrolysis of dandelion and houttuynia cordata by hemicellulase and pectinase, then fermented by Lactobacillus acidophilus and Propionibacterium freudenreichii in sequence, and finally enzymatic hydrolyzed by bromelain and trypsin step by step. The components in the additive are used in combination to have a good effect of promoting intestinal health of pigs, can balance and improve the intestinal microenvironment, improve feed nutrient utilization, enhance immunity, reduce diarrheal diseases, and promote growth and weight gain.

The invention discloses a processing method of fermented cottonseed meal for replacing soybean meal. The method comprises the following steps: uniformly mixing cottonseed meal, feather meal, corn starch and water to obtain a fermentation substrate, adding a first-stage fermentation inoculant into the fermentation substrate for aerobic fermentation, adding a second-stage fermentation inoculant for anaerobic fermentation after fermentation is finished, and performing low-temperature drying and crushing on a fermentation product after fermentation is finished to obtain the cottonseed meal fermented feed. The first-stage fermentation inoculant comprises candida utilis, aspergillus oryzae, papain and cellulase; and the second-stage fermentation inoculant comprises lactobacillus reuteri and lactobacillus acidophilus. According to the method, a bacterium-enzyme synergistic two-step fermentation mode is adopted, bacterium-enzyme synergistic aerobic fermentation is carried out firstly, then anaerobic fermentation is carried out with compound probiotics, and the obtained cottonseed meal fermented feed is high in crude protein and amino acid content and good in palatability, can completely replace soybean meal, can effectively regulate fat metabolism and can improve the lean meat percentage of fattening pigs.