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124 results about "Lactobacillus salivarius" patented technology

Lactobacillus salivarius is a probiotic bacteria species that has been found to live in the gastrointestinal tract and exert a range of therapeutic properties including suppression of pathogenic bacteria.

Medicine for repairing oral mucosa and preparation method thereof

The invention relates to an oral mucosa repairing medicine and a preparation method thereof, and belongs to the technical field of medicines, the medicine comprises barnacle peptide, salivary lactobacillus, resveratrol, a biphasic adhesion matrix, hydroxyapatite, vitamin B family and other components. The preparation method comprises the following steps: sequentially carrying out enzymolysis on barnacle gooseneck by pepsin and lumbrukinase to obtain barnacle peptide. The double-phase adhesion matrix comprises a water-phase matrix, an oil-phase matrix and lecithin; the water-phase matrix contains a chondroitin sulfate-chitosan quaternary ammonium salt compound, sodium alginate and other components; the oil-phase matrix comprises sesame oil, beeswax, a polylactic acid-glycolic acid copolymer and the like. According to the invention, barnacle peptide and salivary lactobacillus are prepared by adopting a special method and are matched with resveratrol for use, so that multi-target and multi-path promotion of oral mucosa repair can be realized; the chondroitin sulfate-chitosan quaternary ammonium salt compound is prepared through electrostatic and physical embedding, the chondroitin sulfate-chitosan quaternary ammonium salt compound is matched with other components to prepare the biphasic adhesion matrix, the biocompatibility is good, the adhesion is high, and the action time of a sustained-release drug is well prolonged.
Owner:HUBEI SHUANGXING PHARMA CO LTD

American ginseng probiotic beverage and preparation method thereof

The invention discloses a panax quinquefolius probiotic beverage and a preparation method thereof, and relates to the technical field of functional foods. According to the beverage, the combination of the American ginseng extract and specific probiotics is taken as a core, the survival rate of thalli is increased by adopting a microcapsule embedding technology, and the product performance is optimized by adding a stabilizer and a flavor regulator. The formula comprises 5-15% of a panax quinquefolius extract, 3-8% of compound probiotic freeze-dried powder (lactobacillus plantarum, lactobacillus salivarius and bifidobacterium lactis), 10-25% of inulin, 5-15% of whey protein, 10-30% of a microcapsule wall material (sodium alginate / chitosan or a WPI-KGM compound), and auxiliary materials. According to the preparation method, the active ingredients are efficiently reserved through the processes of gradient extraction, microcapsule embedding, low-temperature drying and the like. The product has the functions of resisting fatigue, regulating intestinal flora and enhancing immunity, the survival rate of probiotics in simulated gastric juice reaches 85% or above, and the shelf life stability is improved by 40%.
Owner:HONG KONG NATURAL BIOTECHNOLOGY GROUP HOLDINGS CO LTD

Lactobacillus salivarius combination CCFM1327 capable of inhibiting foaming of macrophages and relieving periodontitis

PendingCN120399941ACosmetic preparationsAntibacterial agentsInflammatory factorsPorphyromonas gingivalis
The invention discloses combined lactobacillus salivarius CCFM1327 capable of inhibiting foaming of macrophages and relieving periodontitis, and belongs to the technical field of microorganisms. According to the invention, the strain of combined lactobacillus salivarius CCFM1327 is obtained, and the combined lactobacillus salivarius has the effects of inhibiting foaming of macrophages and relieving periodontitis, which are specifically reflected in that the combined lactobacillus salivarius can inhibit foaming of RAW264.7 cells caused by ox-LDL; the growth of porphyromonas gingivalis can be effectively inhibited; the periodontal probing and diagnosing depth of the periodontitis rats can be obviously reduced; the number of pathogenic bacteria in the oral cavity of the periodontitis rat is reduced; the level of an inflammatory factor IL-17A in serum is reduced; alveolar bone loss of rats suffering from periodontitis is reduced; and the number of alveolar bone osteoclasts is reduced.
Owner:JIANGNAN UNIV

Min pig source lactobacillus salivarius LSM231 for resisting PEDV infection and application of Min pig source lactobacillus salivarius LSM231

The invention discloses a porcine epidemic diarrhea virus (PEDV) infection resistant Min pig source lactobacillus salivarius LSM231 and application thereof, and belongs to the technical field of microorganisms. The Min pig source lactobacillus salivarius is named as Ligilbacillus salivarius LSM231 and is preserved in the China Center for Type Culture Collection, the preservation number is CCTCC NO: M 20242330, and the preservation time is October 25, 2024. The Min pig source lactobacillus salivarius has the advantages that the Min pig source lactobacillus salivarius is named as Ligilbacillus salivarius LSM231 and is preserved in the China Center for Type Culture Collection (CCTCC); the screened Min pig source lactobacillus salivarius is symbiotic probiotics in intestinal tracts and is high in safety performance, and experimental results show that the Min pig source lactobacillus salivarius LSM231 has relatively good antibacterial, acid-resistant and cholate-resistant characteristics, has a remarkable PEDV (porcine epidemic diarrhea virus) resisting effect, and can relieve clinical symptoms caused by PEDV infection and promote growth of piglets, so that the Min pig source lactobacillus salivarius LSM231 can be used for preventing and treating the porcine epidemic diarrhea. The compound can replace antibiotics to be used for preparing a micro-ecological preparation for resisting PEDV (porcine epidemic diarrhea virus) infection.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

Lactobacillus salivarius and application thereof in regulating flora balance of digestive tract of mutton sheep

The invention relates to the technical field of probiotics, in particular to lactobacillus salivarius and application of the lactobacillus salivarius in regulating flora balance of digestive tracts of mutton sheep. The invention provides a lactobacillus salivarius KS1018, and the preservation number of the lactobacillus salivarius KS1018 is CCTCC (China Center for Type Culture Collection) NO: M 2025020. The lactobacillus salivarius KS1018 is a strain which is separated from dolang sheep rumen fluid and has the characteristics of high temperature resistance, acid resistance and cholate resistance, and has the advantages of low immunogenicity and high safety when being applied to mutton sheep. Due to the high-temperature-resistant characteristic, high stability can be kept in the feed mixing and processing process, and the application effect is further improved. The acid-resistant and cholate-resistant characteristics can reduce the influence of the digestive tract on the activity of the feed additive, so that the feed additive effectively plays a role in the digestive tract of the ruminant. The strain is good in palatability after being fed, and can effectively regulate digestive tract flora of ruminants, restore digestive tract flora balance and improve the disease-resistant potential of the ruminants.
Owner:CHINA AGRI UNIV

Feed additive for improving immunity of pet cats as well as preparation method and application of feed additive

The invention provides a feed additive capable of improving immunity of pet cats as well as a preparation method and application of the feed additive, and belongs to the technical field of animal feed additives. The feed additive comprises probiotics and a traditional Chinese medicine extract, the probiotics comprise bifidobacterium animalis, combined lactobacillus salivarius and saccharomyces cerevisiae boulardii, and the traditional Chinese medicine extract comprises astragalus polysaccharide, curcumin and resveratrol. The probiotics directly enhance intestinal immunity through colonization resistance and metabolites, the traditional Chinese medicine components form internal and external dual defense through system immune activation, immunity-flora dual regulation is achieved, the probiotics and the traditional Chinese medicine extract form a symbiotic system of increasing the drug effect through bacteria and protecting the bacteria through drugs, and 1 + 1gt is achieved; and 2, the immunity improving effect is achieved.
Owner:JINLING INST OF TECH

Probiotic and use thereof

Disclosed in the present invention is a probiotic. The probiotic comprises Parabacteroides distasonis with the microbial deposit number of CCTCC NO: M20222033, Limosilactobacillus fermentum with the microbial deposit number of CCTCC NO: M2023352, Lactobacillus salivarius with the microbial deposit number of CCTCC NO: M2023348, Enterococcus avium with the microbial deposit number of CCTCC NO: M2023350, and Bifidobacterium bifidum with the microbial deposit number of CCTCC NO: M2023349. The probiotic has good safety, has antioxidant activity, can inhibit pathogenic bacteria, can alleviate colon injury, can inhibit inflammation, and can alleviate diarrhea caused by chemotherapeutic drugs.
Owner:SICHUAN ANAEROBIC BIOTECHNOLOGY CO LTD

Lactobacillus salivarius combination CCFM1332 with multi-target regulation effect and application of lactobacillus salivarius combination CCFM1332 in periodontitis

The invention discloses combined lactobacillus salivarius CCFM1332 with a multi-target regulation effect and application of the combined lactobacillus salivarius CCFM1332 in periodontitis, and belongs to the technical field of microorganisms. The invention discloses a strain of combined lactobacillus salivarius CCFM1332, and the combined lactobacillus salivarius not only has a vaginal immune regulation effect, but also has an effect of relieving periodontitis, which is specifically embodied in that: the combined lactobacillus salivarius can promote vaginal epithelial cells VK2 / E6E7 to secrete antibacterial peptides; the periodontal probing and diagnosing depth of the periodontitis rats can be reduced; the number of pathogenic bacteria in the oral cavity of the periodontitis rat is reduced; the levels of inflammatory factors IL-1beta, IL-6 and IL-17A in serum are reduced; alveolar bone loss of rats suffering from periodontitis is reduced, and the alveolar bone absorption condition of the rats is effectively relieved.
Owner:JIANGNAN UNIV

Postbiotic composition for effectively inhibiting dental caries in oral cavity and preparation method thereof

The invention belongs to the technical field of biomedical treatment and biological fermentation, discloses a metagen composition for effectively inhibiting oral dental caries and application thereof, and aims to solve the problems of great side effect, weak effect and unknown mechanism of the existing dental caries prevention and treatment means. The composition is prepared by mixing a metagen 1 which is prepared by fermenting lactobacillus salivarius Postbio-YY with a metagen 2 which is prepared by fermenting lactococcus lactis Postbio-F3 and lactobacillus paracasei Postbio-P6 step by step. In the preparation process, the active ingredients are reserved by accurately controlling the fermentation pH, time and pasteurization parameters. The composition can be prepared into multiple dosage forms such as toothpaste and the like, can remarkably inhibit the growth of streptococcus mutans and destroy the thallus structure, inhibits biofilm and exopolysaccharide synthesis by down-regulating fimI, wcaJ and wcae genes, is safe and free of side effects, and provides an efficient scheme for decayed tooth prevention and treatment.
Owner:YANGZHOU PERFECT DAILY CHEM

Vaginal active lactobacillus and application thereof

The invention belongs to the technical field of microorganisms, and particularly relates to combined lactobacillus salivarius and application thereof in female genital tract health. The preservation number of the strain is CCTCC NO: M20231719, and the strain has good bacteriostatic ability and dendritic cell (DC) maturation / activation stimulation ability, has no potential safety problem, can regulate vaginal micro-ecological balance, prevent infection caused by exogenous bacteria, effectively improve tumor immunosuppression microenvironment, and has good application prospects. And the method has very important significance on prevention / treatment of vaginal dysbacteriosis patients, gynecological tumors and precancerous lesions thereof.
Owner:CHENGDU BEITEYI KANGEN BIOMEDICAL TECHNOLOGY CO LTD

Application of chicken-derived saliva combined lactobacillus in laying hens in later laying period

The invention discloses application of chicken-derived saliva combined lactobacillus in laying hens in the later egg laying period. The chicken-derived saliva combined lactobacillus is used for preparing products for improving the production performance of the laying hens in the later egg laying period, improving the oxidation resistance of the laying hens in the later egg laying period and / or improving the egg quality of the laying hens in the later egg laying period. The chicken source combined lactobacillus salivarius is RS-11-1, is classified and named as the combined lactobacillus salivarius, is registered and preserved in China General Microbiological Culture Collection Center (CGMCC) on November 12, 2024, and has the preservation number of CGMCC No.32589. The chicken source combined lactobacillus salivarius has the advantages that the chicken source combined lactobacillus salivarius can be used for preparing the chicken source combined lactobacillus salivarius, and the chicken source combined lactobacillus salivarius can be used for preparing the chicken source combined lactobacillus salivarius; the chicken-derived saliva combined with lactobacillus can improve the intestinal health of laying hens in the late egg laying period, enhance the oxidation resistance of intestinal tracts, and improve the egg laying performance and egg quality of the laying hens in the late egg laying period.
Owner:SOUTHWEAT UNIV OF SCI & TECH

Application of lactobacillus salivarius in preparation of products for improving metabolism of alcohol and uric acid

The invention relates to the technical field of marine microorganisms, in particular to application of combined lactobacillus salivarius in preparation of products for improving metabolism of alcohol and uric acid, the combined lactobacillus salivarius NHNK-603 is preserved in the China Center for Type Culture Collection, and the preservation number is CCTCC NO: M 2024416. Experiments show; the NHNK-603 has the effects of inhibiting the growth of klebsiella pneumoniae, inhibiting the production of alcohol, agglutinating the klebsiella pneumoniae, inhibiting the virulence gene of the klebsiella pneumoniae, promoting alcohol metabolism, reducing alcohol damage, tolerating alcohol, degrading uric acid, inhibiting the activity of xanthine oxidase, promoting uric acid excretion, promoting the proliferation of Alistipes indinctus and synthesizing hippuric acid; the thallus biofilm increases the function of colonization on mucoprotein and intestinal epithelial cells, and can be applied to preparation of products for improving metabolism of alcohol and uric acid.
Owner:QINGDAO NOVO NUOKANG BIOTECHNOLOGY CO LTD

Genetic engineering saliva combined lactobacillus and application thereof

The invention relates to genetic engineering combined lactobacillus salivarius and application of the genetic engineering combined lactobacillus salivarius. The strain is classified and named as combined lactobacillus salivarius CTMT2, and the preservation number of the strain is CCTCC (China Center for Type Culture Collection) M 2025547. After an NIAAA model is injected into the stomach of an alcoholic liver mouse, the acetaldehyde level of the liver of the mouse is obviously reduced, and the alcoholic fatty liver symptom of the mouse is obviously relieved; after long-term intragastric administration of a high-glucose and high-fat modeling mouse, the acetaldehyde level in excrement of the mouse can be obviously reduced, the progress of liver fibrosis is improved, and good application prospects are achieved.
Owner:SHANGHAI SIXTH PEOPLES HOSPITAL

A fermentation process and application of wheat germ

ActiveCN118303506BBiotechnologyWheat germ
This invention discloses a fermentation process and application of wheat germ, belonging to the field of feed additive technology. The fermentation process includes the following steps: mixing Bacillus coagulans powder (accession number CGMCC No. 1.17145), Lactobacillus salivarius powder (accession number CCTCC NO: M 2022848), and steam-sterilized and cooled wheat germ; performing solid-state fermentation in a sealed environment; and then sterilizing with ozone after fermentation to obtain fermented wheat germ. This invention produces highly nutritious fermented wheat germ through simple steps. This fermented wheat germ can be used as a feed additive for laying hens, improving their production performance.
Owner:HEBEI NORMAL UNIVERSITY OF SCIENCE & TECHNOLOGY +1

Composition for inhibiting streptococcus angina and preparation method thereof

The invention provides a composition for inhibiting streptococcus angina and a preparation method of the composition, and belongs to the technical field of medicines. The preparation method comprises the following steps: carrying out water extraction on purslane and ginseng to obtain polysaccharide and an anti-inflammatory composition, mixing the anti-inflammatory composition and antibiotics, embedding the mixture in beta-cyclodextrin, forming a compound by the prepared inclusion compound, a magnetic gold nanocage and a probiotic secretion compound, loading the compound on lactobacillus salivarius LS02, uniformly mixing the compound with lactobacillus reuteri FPHC2951, lactobacillus acidophilus LA16 and polysaccharide, and carrying out freeze-drying to obtain the anti-inflammatory compound. The composition for inhibiting the streptococcus angina is prepared. The composition for inhibiting the streptococcus anginiae has good targeted inhibition and killing effects on harmful bacteria streptococcus anginiae, does not have drug resistance, has small side effects, is high in patient compliance, has good anti-oxidation, anti-inflammatory and antibacterial effects, is good in biocompatibility, and has a wide application prospect.
Owner:JIANGSU XINSHENAO BIOTECHNOLOGY CO LTD

A saliva-combined lactobacillus 8-2 strain and its application

The present invention provides a salivarius lactobacillus 8-2 strain and an application thereof, wherein the salivarius lactobacillus 8-2 strain has been deposited in the General Microbiology Center of the China Microbiological Culture Collection Administration Committee, and the deposit number is CGMCC NO.30612. The salivarius lactobacillus described in the present invention has good acid resistance, is non-hemolytic, has strong antibacterial ability, can reduce the damage caused by salmonella infection, and can effectively promote the absorption function of intestinal mucosa, improve the production performance of laying hens, has the potential to be developed into a high-quality probiotic preparation for laying hens with both "antibiotic replacement" function and the function of promoting the repair of intestinal mucosal damage, and can be used in the preparation of laying hen antibiotic substitutes, including the application of the fermentation supernatant of the strain in the preparation of laying hen antibiotic substitutes.
Owner:ZHEJIANG UNIV +1

Lactobacilli for treating cardiac dysfunction

The use of a bacterium of the species Lactobacillus salivarius in the manufacture of a food product, dietary supplement or medicament for treating cardiac dysfunction, particularly myocardial infarction, congestive heart failure, dilated cardiomyopathy or inflammatory heart disease (including endocarditis, inflammatory cardiomegaly and myocarditis) is disclosed.
Owner:INT N&H DENMARK APS

Pharmaceutical composition for repairing oral gingivitis and preparation method thereof

The invention relates to a pharmaceutical composition for repairing oral gingivitis and a preparation method thereof, and belongs to the technical field of biological medicine, the pharmaceutical composition comprises a lactobacillus salivarius fermentation extract, a herba violae extract, golden cicada nymph extract peptide, guava polyphenol and resveratrol; the lactobacillus salivarius fermentation extract is obtained by carrying out aerobic fermentation and anaerobic fermentation on lactobacillus salivarius to obtain a fermentation product, and purifying and extracting the fermentation product through an XAD7HP macroporous adsorption resin column; the philippine violet herb extract is obtained by performing enzymolysis on whole philippine violet herb through pectinase and cellulase and then performing enzymolysis through compound protease to obtain zymolyte, and purifying and extracting the zymolyte through a compound adsorption column. The golden cicada nymph extracted peptide is obtained by purifying and extracting 5kDa zymolyte obtained by performing step-by-step enzymolysis on golden cicada nymphs through papain and trypsin through a Q agarose gel FF adsorption column. All the components are matched for use according to a certain proportion, so that the antibacterial coating is capable of precisely resisting bacteria, has efficient anti-inflammatory and anti-oxidation properties, and is safe and reliable.
Owner:HUBEI SUIZHOU SHUANGXING BIOLOGICAL SCI & TECH CO L

Application of combined lactobacillus salivarius NHNK-603 in preparation of product for improving tooth color and gingivitis

The invention relates to the technical field of marine microorganisms, in particular to application of lactobacillus salivarius NHNK-603 in preparation of products for improving tooth color and gingivitis. The strain provided by the invention is preserved in the China Center for Type Culture Collection, and the preservation number is CCTCC NO: M 2024416. Experiments show; the NHNK-603 has the effects of inhibiting proliferation and biofilm formation of pigment-generating pathogenic bacteria, agglutinating the pigment-generating pathogenic bacteria, inhibiting melanin generation of the pigment-generating pathogenic bacteria, inhibiting hyaluronidase activity of the pathogenic bacteria, promoting growth of gingival fibroblasts, inhibiting gingival cell inflammation and apoptosis induced by the pigment-generating pathogenic bacteria, and inhibiting melanin generation of the pigment-generating pathogenic bacteria. And the product can be used for preparing products for improving tooth color and gingivitis.
Owner:QINGDAO NOVO NUOKANG BIOTECHNOLOGY CO LTD

Comprehensive bacterial composition for odor reduction

Use of a composition comprising bacteria for odor reduction in the treatment of symptoms of tissue necrosis, wound secretions or putrid wounds or a disease selected from the group consisting of ozena, hyperhidrosis, osmidrosis, chronic urinary tract infections, chlamydial infections and halitosis; wherein the composition comprises the bacteria Lactobacillus acidophilus TYCA15, Lactobacillus salivarius, Bifidobacterium animalis, Bifidobacterium bifidum and Bifidobacterium longum in the ratio 1:1:1:1:1; and the composition totals 10 9 bacteria per gram of the composition.
Owner:WEISENSEE BENEDIKT +1

Method for improving eggshell quality of laying hens in later egg laying period by adding lactobacillus salivarius into feed

The invention discloses a method for improving egg shell quality in the later egg laying period of laying hens by adding intestinal probiotics into feed, and belongs to the technical field of healthy poultry breeding. According to the method, specifically enriched lactobacillus salivarius is screened based on correlation analysis of intestinal flora and eggshell quality. The strain is added into basic ration of laying hens in the later egg laying period according to a certain proportion (preferably 150 mg / kg feed) in the form of bacterial powder with the viable count not lower than 1 * 10 < 9 > CFU / g, and the laying hens are continuously fed for at least 8 weeks. According to the method, the laying rate and the average daily egg weight of the laying hens in the later laying period can be remarkably increased, the eggshell thickness and strength are effectively improved, and the egg breaking rate is reduced. The strain screening method provided by the invention is scientific, clear in application effect, safe and free of residues, and an effective green solution is provided for solving the problem that the eggshell quality is reduced in the later egg laying period of laying hens.
Owner:SHIHEZI UNIVERSITY

Probiotic composition for improving health of oral cavity and upper respiratory tract and preparation method thereof

The invention belongs to the technical field of health-care products, and particularly relates to a probiotic composition for improving health of an oral cavity and an upper respiratory tract and a preparation method of the probiotic composition. Oral health is an important component of whole body health. Bacterial infections in the oral cavity, such as caries and periodontal diseases, not only influence the oral cavity, but also possibly harm the whole body health and influence the quality of life. The oral cavity is a portal of the respiratory tract, and bad oral hygiene may cause the accumulation of tartar, plaque, soft dirt and the like in the oral cavity and becomes a repository of pathogenic bacteria of the respiratory tract. When the immunity is low, the bacteria may enter the lung through the respiratory tract to cause respiratory tract and even lung infection. The invention discloses a probiotic composition for improving health of oral cavity and upper respiratory tract, which has the effects of resisting inflammation, resisting infection, preventing decayed teeth, protecting oral mucosa, preventing and treating bad breath and the like through the synergistic effect of streptococcus salivarius subsp. Thermophilus K12, lactobacillus rhamnosus CRL1505, lactobacillus salivarius NHNK612, lactobacillus mucus NHNK606 and the like.
Owner:QINGDAO VITALILAI FOOD CO LTD

Methods and compositions to modulate antibiotic resistance and gastrointestinal microbiota

Disclosed herein are methods and compositions related to probiotic formulas. These formulas comprise the bacterial strain Lactobacillus crispatus WZ-12 or a derivative thereof. Other strains which can be included in the composition include, but are not limited to, Lactobacillus salivarius 1-14, or Lactobacillus reuteri 2-2, and derivatives thereof. These compositions can be used in a variety of methods to treat and / or ameliorate diseases, such as colonization of antibiotic-resistant bacteria in the host organism. Also disclosed herein are methods of treating those subjects in need thereof by administering the compositions disclosed herein.
Owner:OHIO STATE INNOVATION FOUND

Probiotic for the treatment of infertility and recurrent miscarriage

The present invention relates to a Lactobacillus salivarius strain deposited at the Spanish Type Culture Collection (CECT) under the accession number 5713, or a mutant thereof, for use in the treatment and / or prevention of infertility or recurrent miscarriage in a female subject. Furthermore, the present invention relates to an in vitro monitoring method for monitoring the therapeutic effect of the treatment of infertility or recurrent miscarriage in a female subject with a Lactobacillus salivarius strain deposited at the CECT under the accession number 5713, or a mutant thereof.
Owner:BIOSEARCH SA

A feline oral care probiotic composition and uses thereof

ActiveCN116200307BBiotechnologyMouth care
The application discloses a cat oral cavity nursing probiotic composition and application thereof, and the probiotic composition comprises animal bifidobacterium and lactic acid bacteria, wherein the lactic acid bacteria is any one or a combination of multiple of salivarius, lactobacillus casei, enterococcus faecalis, lactobacillus rhamnosus, lactobacillus plantarum, lactobacillus acidophilus and lactobacillus reuteri; compared with single probiotic, the probiotic composition has better effect on oral cavity odor removal, can effectively improve cat oral cavity source halitosis, and can also reduce dental plaque formation, relieve gingivitis and dental caries, and can be applied to preparation of a cat oral cavity odor cleaner, and has good application prospect.
Owner:JUNWEIAN (WUHAN) LIFE TECHNOLOGY CO LTD

Primer composition and application thereof

The invention discloses a primer composition for detecting bifidobacterium bifidum of which the microbial preservation number is CCTCC (China Center for Type Culture Collection) NO: M2023349, enterococcus avium of which the microbial preservation number is CCTCC NO: M2023350, lactobacillus salivarius of which the microbial preservation number is CCTCC NO: M2023348, lactobacillus fermentum of which the microbial preservation number is CCTCC NO: M2023352, and parabacteroides didysonii of which the microbial preservation number is CCTCC NO: M20222033. The invention further discloses a kit based on the primer composition and application of the kit. The primer composition has good specificity and high accuracy aiming at the five bacteria, and can detect the five bacteria in a complex environment to evaluate the physiological status of a subject.
Owner:SICHUAN ANAEROBIC BIOTECHNOLOGY CO LTD

Compound microorganism feed additive for promoting growth of livestock and poultry

The invention discloses a compound microorganism feed additive for promoting the growth of livestock and poultry. The compound microorganism feed additive comprises microorganism strains, natural plant components and auxiliary materials, the microbial strains comprise 8 to 12 parts of candida utilis, 5 to 9 parts of bacillus licheniformis, 2 to 4 parts of bacillus subtilis, 8 to 12 parts of aspergillus niger, 8 to 12 parts of lactobacillus delbrueckii, 8 to 12 parts of lactobacillus acidophilus, 8 to 12 parts of bifidobacterium and 3 to 7 parts of lactobacillus salivarius; the natural plant components comprise 0.5 to 2 parts of moringa seed powder; the auxiliary materials comprise 20 to 30 parts of cane sugar, 10 to 15 parts of fish meal, 2 to 3 parts of grease, 10 to 20 parts of soybean meal, 5 to 10 parts of pupa powder, 10 to 15 parts of zinc lactate, 1 to 2 parts of calcium gluconate, 3 to 5 parts of calcium carbonate and 2 to 4 parts of paeonol. Microbial strains in the compound microbial feed additive can generate various growth regulatory factors such as vitamins, amino acids and organic acids, so that the growth and development of livestock and poultry are stimulated, and the growth speed is increased.
Owner:HENAN SMEC BIOENGINEERING CO LTD

Lactobacillus metabolism complex as well as preparation method and application thereof

The invention is applicable to the field of methods for lowering lipid and conditioning intestinal tracts, and provides a lactobacillus metabolic complex as well as a preparation method and application thereof, the lactobacillus metabolic complex is secreted by lactobacillus salivarius SNK-6, the lactobacillus salivarius SNK-6 is preserved in China General Microbiological Culture Collection Center on January 17, 2018, and the preservation number of the lactobacillus salivarius SNK-6 is CCTCC No: M2018044. The lactobacillus metabolic complex provided by the invention has a remarkable effect of preventing and treating fatty liver, and can regulate intestinal flora and enhance intestinal health at the same time. The compound has multiple effects of lowering lipid, resisting inflammation and resisting oxidation, and is superior to a single component. The preparation method of the metabolic complex is simple, low in cost and suitable for large-scale production. The compound is high in safety and free of toxic and side effects, and can be applied to the fields of medicine and health care as a functional food or a medicine additive.
Owner:SHANGHAI ACAD OF AGRI SCI

Composition and kit for preventing or treating atopic eczema and application thereof

In some embodiments, a composition comprising an effective amount of Bifidobacterium breve, Bifidobacterium bifidum, and Lactobacillus salivarius is provided. In some embodiments, the use of the composition in the prevention or treatment of atopic eczema in a subject is provided. In some embodiments, there is provided a method of preventing or treating atopic eczema in a subject, the method comprising the step of administering to the subject an effective amount of the composition. In some embodiments, there is provided a kit comprising: a composition of any one of the examples herein; and at least one container selected from the group consisting of capsules, pouches, packets, sachets, bottles, and blister packages. Other exemplary embodiments are described herein. In certain embodiments, the compositions are safe to use and effective to prevent or treat atopic eczema in a subject, especially an adult subject.
Owner:MICROBIOTA I CENT MAGIC LTD

Deodorizing disinfectant for pets as well as preparation method and application of deodorizing disinfectant

The invention discloses a pet deodorization disinfectant as well as a preparation method and application thereof. The deodorization disinfectant is prepared from a metabolite of a specific strain lactobacillus salivarius NJAUTYRGJ-Y (the preservation number is CCTCC NO: M 20242787), a plant extract, a disinfectant and salt components. The deodorant disinfectant can be directly sprayed on pet excrement, urine and living environment, and efficient deodorization and disinfection are realized. The deodorization disinfectant has a remarkable deodorization effect on excrement, urine and ammonia gas, and the deodorization effect lasts for a long time; the antibacterial agent has a good antibacterial effect on common pathogenic bacteria (staphylococcus aureus, escherichia coli and klebsiella pneumoniae), and also has a good disinfection effect on excrement, urine and air. In addition, the deodorant disinfectant has good safety, has no toxic or side effect, and is suitable for safe disinfection of pet living environment.
Owner:NANJING AGRICULTURAL UNIVERSITY +1