1774results about How to "Lower dose" patented technology

Two-dimensional or three-dimensional, time-resolved CT frame images are acquired during a dynamic study of a subject. A composite image is produced and this is used to reconstruct each CT frame image by weighting the backprojection of each projection view acquired for that image frame by the corresponding value in the composite image. This weighted backprojection enables artifact-free image frames to be produced with far fewer projection views of the subject. The composite image may be reconstructed from views acquired separately, or it may be produced by combining views acquired during the course of the dynamic study.

The invention relates to a herbicide composition, containing sulfonylurea or salt thereof, pyridine and cyhalofop-butyl as active ingredients with the weight ratio of 0.1 to 5: 0.1 to 10: 0.1 to 10. Compared with herbicides with single dose, the weed control effect of the herbicide composition of the invention is obviously improved, thereby reducing the using dosage, reducing the influence degreefor the environment while reducing the pesticide cost, simultaneously enlarging weed control spectrum, and having good control efficiency for Gramineae and broadleaf weeds in rice paddy fields.

The invention relates to a herbicide composition, containing sulfonylurea or salt thereof, pyridine and penoxsulam as active ingredients with the weight ratio of 0.1 to 5: 0.1 to 10: 0.1 to 10. Compared with herbicides with single dose, the weed control effect of the herbicide composition of the invention is obviously improved, thereby reducing the using dosage, reducing the influence degree for the environment while reducing the pesticide cost, simultaneously enlarging weed control spectrum, and having good control efficiency for Gramineae and broadleaf weeds in rice paddy fields.

The invention provides a fungicide composition containing an active component A and an active component B, and application thereof in preventing and controlling various agricultural fungal diseases. The active component A in the composition is one of two methoxyl acrylic ester compounds; and as shown above, the active component B of the compound A1 and the compound A2 is one of the following fungicide varieties: thiocarbamate compounds or salt thereof, aliphatic compounds or salt thereof, carbamate compounds or salt thereof, oxazole compounds or salt thereof, thiazole compounds or salt thereof, amide compounds or salt thereof, organophosphorus compounds or salt thereof, imidazole compounds or salt thereof, antibiotic compounds or salt thereof, pyridine compounds or salt thereof and triazole compounds or salt thereof.

Scintillator compositions having a garnet crystal structure useful for the detection of high-energy radiation, such as X, beta, and gamma radiation, contain (1) at least one of terbium and lutetium; (2) at least one rare earth metal; and (3) at least one of Al, Ga, and In. Terbium or lutetium may be partially substituted with Y, La, Gd, and Yb. In particular, the scintillator composition contains both terbium and lutetium. The scintillators are characterized by high light output, reduced afterglow, short decay time, and high X-ray stopping power.

A control device and a drug delivery system containing such a control device are disclosed for delivery to a patient of a drug or a placebo (or ineffective dose of the drug) according to a partial reinforcement schedule, whereby the placebo (or ineffective dose of the drug) is delivered in whole or in part during one or more delivery events. Methods of modulating the drug/placebo delivery to a patient are also provided, whereby the delivery event is initiated either according to a patient-initiated signaling event (i.e., a self-medication mode) or an automated signaling event (i.e., automated mode).

The invention relates to a strain used as hametz of microorganism, belonging to technical field of processing agricultural microorganism and food, which comprises the strain and the compound hametz ofplant lactocin as well as the application. The invention is characterized in that: the microzyme-Custer bouquet yeast strain can obtain by separating and filtering, which is suitable for fermenting the rice steamed sponge cake; the yeast strain is preserved in Chinese typical culturing and preserving centre and the preserved number is CCTCC NO: M207150. The microorganism compound hametz can be made by the ZSM-001 Custer bouquet yeast strain and AS1.510 plant lactocin (Lactobacillus plantarum), and can be used in rice fermented products, such as rice steamed sponge cakes. The invention has theadvantages of good fermenting performance and easy commercial process, and the products made by the invention have a typical sweet and sour perfume.

The invention provides a [(indole-3-yl)pyrimidine-2-yl]aminophenylpropyl-2-eneamide derivative and its salt, a preparation method of the derivative, and application of the derivative and the salt. The [(indole-3-yl)pyrimidine-2-yl]aminophenylpropyl-2-eneamide derivative has a structure shown in the formula I below. Deuterium-carbon bonds in the derivative enable the derivative to decompose slowly in a human body, a medicament of the derivative has a longer half-life period and a higher concentration in blood, the dosage of the medicament is finally reduced, and toxic and side effects of the medicament are decreased. Experiments show that compared with AZD 9291 mesylates, AZD 929-D9 mesylate of the deuterium-substituted derivative has Cmax which is 1.32 times as high as that of AZD 9291, exposed dose 1.41 times as high as that of AZD 9291, and elimination half-life 1.31 times as long as that of AZD 9291.

The invention provides a herbicide combination, containing Trifloxysulfuron, Pyrithiobac-sodium, APP and/or Cyclohexenone, and the ratio of parts by weights of Trifloxysulfuron: Pyrithiobac-sodium:APP and/or Cyclohexenone is 0.1:1:20-20:1:0.1. The combination can be used to prepare emulsifiable solution, liquor, thick emulsion, microemulsion, wettable powder, water suspending agent, oil suspending agent, water-dispersible granules or soluble powder (granules). The herbicide combination can be used to prevent and control Gramineae and broad-leaved weeds which have grown for one year or more than one year in the cotton field.

A spectrometer for detecting and quantifying elements in a sample. An exciter ionizes atoms in the sample, and the atoms thereby produce characteristic x-rays. A detector receives the x-rays and produces signals based on the x-rays. A filter system selectively blocks the x-rays from attaining the detector. The selective blocking of the x-rays is accomplished based on an energy of the x-rays. An analyzer receives the signals from the detector and detects and quantifies the elements in the sample based at least in part on the signals. In this manner, detector receives the light element x-rays, and the medium and heavy element x-rays are filtered out to avoid overwhelming the detector. This invention combines the large solid angle, high efficiency, and ability to measure the continuous background spectrum of the energy dispersive x-ray detector with the selectivity of the wavelength dispersive x-ray detector. It thus enables faster and more accurate measurement of light elements in thin films. This invention enhances the light element performance of a system by enabling higher throughput, lower e-beam and x-ray dose to the sample, and improved accuracy from the capability to measure the background radiation.

The invention provides an artificial blood vessel loaded with pseudo-ginseng medicines, and a preparation method and application for the artificial blood vessel. The artificial blood vessel sequentially consists of an inner layer, a middle layer and an outer layer which are closely connected with one another; the outer layer consists of nondegradable polymer materials; the middle layer consists of degradable high polymer materials and pseudo-ginseng powder distributed on the surface and/or the inside of the middle layer; the inner layer consists of degradable natural biological materials and pseudo-ginseng powder distributed on the surface and/or the inside of the inner layer; the mass percent of the pseudo-ginseng powder in the inner layer is larger than 5%; the content of the pseudo-ginseng powder in the middle layer is higher than that of the pseudo-ginseng powder in the inner layer; the outer layer is a nondegradable layer and is mainly used for protecting and replacing a blood vessel for a long time; the middle layer is a long-acting antithrombosis layer, can degrade high polymers, and can slowly release medicines so as to realize a long-acting antithrombosis effect; and the inner layer is a quick degrading layer, when the blood vessel is punctured and injured by a foreign object, the pseudo-ginseng medicines wrapped in the blood vessel are directly exposed on a wound, blood is stopped quickly, and the artificial blood vessel is particularly suitable for application to products such as hematodialysis.

The present invention provides for silk fibroin-based compositions comprising one or more antibiotic agents for prevention or treatment of microbial contamination, methods of making antibiotic-containing silk scaffold, methods of stabilizing antibiotics in silk scaffolds, and methods for preventing or treating microbial contamination using the antibiotic-containing compositions. Various methods may be used to embed the antibiotic(s) into the silk fibroin-based compositions. The antibiotic-containing compositions of the invention are particular useful for stabilizing antibiotics, preventing bacterial infections, and for medical implants, tissue engineering, drug delivery systems, or other pharmaceutical or medical applications.

To intraoperatively generate an updated volume data set in which a image information of biological tissue is volume data set representing reconstructed from a series of n 2D biological tissue x-ray projections, one version, in intraoperatively acquired m 2D biological tissue x-ray projections the biological tissue 2D contour is segmented and this is back-projected in the reconstructed volume data set. In another version, in the volume data set the biological tissue 3D contour is segmented and this is projected in intraoperatively acquired m biological tissue 2D x-ray projections. The 3D contour is visually repositioned by projection in the m 2D x-ray projections in the volume data set, until its projection is substantially congruent with the biological tissue image information in the respective 2D x-ray projections. In both versions, a volume data set updated around the intraoperatively determined biological tissue 3D contour is generated.

1,2-disubstituted heterocyclic compounds which are inhibitors of phosphodiesterase 10 are described. Also described are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. Among the disorders which may be treated are neurological, neurodegenerative and psychiatric disorders including, but not limited to, those associated with cognitive deficits or schizophrenic symptoms.

The invention discloses a pesticide compound containing penoxsulam and cyhalofop-butyl, and the application thereof; the compound comprises commonly used additive, penoxsulam and cyhalofop-butyl; the weight part ratio of the penoxsulam to the cyhalofop-butyl is 1:1 to 1:20; and the weight percentage of the total weight of the penoxsulam and the cyhalofop-butyl in the pesticide compound is 5 to 80percent. The invention is used for preventing and removing annual grassy weeds in a paddy field. The prevention effect of the invention has significant synergic or adding effect than the single dose,and the invention reduces the used dose of the pesticide, reduces the medication cost, prolongs the service life of the preparation and reduces the adverse impact of the pesticide on the ecological environment.

The invention discloses a eugenol biological pesticide which comprises the following ingredients in percentage by weight: 0.1% to 70% of eugenol, 6% to 20% of surfactant, 0.01% to 0.5% of plant immunity regulator, 10% to 50% of synergist, and raw materials of alcohol and turpentine for the rest part. With the advantage of reasonable formula, the eugenol biological pesticide is characterized in that the active volatility of the active ingredient eugenol is improved, the pesticide effect of the eugenol is enhanced, pesticide doses are reduced, and the pesticide cost for farmers is reduced; pureplant solvents are used in the eugenol biological pesticide which belongs to low-carbon and environment-friendly pesticide, so pollution and harm to the environment are reduced, and the eugenol biological pesticide is safe and environment friendly for use. The eugenol biological pesticide is used for preventing and treating powdery mildew, botrytis and downy mildew and regulating plant immunity, and has the effects of synergy, simultaneous treatment, resistance prevention, resistance delay, etc.

The invention relates to a herbicide composition, containing sulfonylurea or salt thereof, pyridine and acetochlor as active ingredients with the weight ratio of 0.1 to 5: 0.1 to 10: 0.1 to 10. Compared with herbicides with single dose, the weed control effect of the herbicide composition of the invention is obviously improved, thereby reducing the using dosage, reducing the influence degree for the environment while reducing the pesticide cost, simultaneously enlarging weed control spectrum, and having good control efficiency for Gramineae and broadleaf weeds in rice paddy fields.

The invention relates to a synergistic bactericide composition, in particular to a bactericide composition which comprises synergistically effective amount of kresoxim-methyl and any one of bactericidal active ingredients selected from the group consisting of diniconazole, flutriafol, triadimefon, thiophanate methyl, benomyl, prochloraz, ethirimol, bromothalonil, mancozeb, ziram, polyoxin, zhongshengmycin and wuyiencin.

The invention discloses a coreopsis tinctoria nutt extract and application of the coreopsis tinctoria nutt extract in preparation of medicines for treating hyperlipemia and anti-oxidation medicines. A method for preparing the coreopsis tinctoria nutt extract comprises the following steps: performing reflux extraction on a coreopsis tinctoria nutt medicinal material for 2-3 times by 12-25 times of 30-75% ethanol the amount of which is 12-25 times of the amount of the coreopsis tinctoria nutt medicinal material; mixing extract liquids, and concentrating to obtain extracting concentrate; diluting the extracting concentrate by water; refining by an AB-8 macroporous resin; sequentially eluting by water, 10% ethanol, 50-75% ethanol and 95% ethanol, and collecting the part eluted by 50-75% ethanol; concentrating and drying. The coreopsis tinctoria nutt extract comprises 10 flavones serving as main components, wherein the total content of marein and flavanomarein is more than 10 percent. Animal in-vivo experiments indicate that the coreopsis tinctoria nutt extract has a certain blood-fat regulating effect; and in-vitro anti-free radical scavenging experiments indicate that the coreopsis tinctoria nutt extract has a certain anti-oxidation effect, and flavanomarein, marein and the like are main anti-oxidation components.

The invention discloses a pesticide composition containing Bacillus thuringiensis and chlorantraniliprole. The pesticide composition comprises common aids, Bacillus thuringiensis and chlorantraniliprole; wherein the weight part ratio of Bacillus thuringiensis to chlorantraniliprole is 20:1-1:20; and Bacillus thuringiensis and chlorantraniliprole account for 1 to 60 percent of the weight of the pesticide composition. The aid is one or more of the following agents: solvent, an emulsifier, a wetting agent, a stabilizer, a dispersant, a thickener, a PH regulator, an anti-foaming agent, an antifreezer, and a filler. The pesticide composition is used for controlling Lepidoptera pests on crops, and is quick in response and long in persistence compared with a single agent; and the pesticide dosage and the cost are reduced, and environmental protection and comprehensive control over crop pests are facilitated.

The invention discloses a medicinal composition for treating or preventing the obesity and metabolic syndromes, and belongs to the medicine field. The medicinal composition treats orlistat and acarbose as medicinal active components, so the application amount of orlistat in the medicinal composition is substantially reduced, thereby the risk of the damage of orlistat to the liver of a body is reduced. The medicinal composition has a substantial synergistic effect when the medicinal composition is used for treating or preventing the obesity and the metabolic syndromes, can reduces the diabetes and angiocardiopathy suffering risks of obese patients, and has a wide medical application prospect.

The present invention belongs to the field of insecticides, and relates to a pest-killing and mite-killing composition, which contains an active component A and an active component B, a weight part ratio of the component A to the component B is 1:99-99:1, the active component A is selected from a compound I represented by the following structural formula, the active component B is selected from an organic phosphorus pest/mite killing agent, a nicotine type acetylcholine receptor (nAChR) agonist pest/mite killing agent, an apastia pest/mite killing agent, a proton gradient interference and oxidative phosphorylation affecting uncoupling pest/mite killing agent, a nereistoxin analog pest/mite killing agent, a Ryania receptor regulating pest/mite killing agent, a voltage-dependent sodium ion channel blocking pest/mite killing agent, an ecdysone receptor stimulating pest/mite killing agent, an amino butyric acid (GABA) gated chloride channel antagonism pest/mite killing agent, a microorganism pest/mite killing agent or other pest/mite killing agents, and the active component A has the following structure. The composition of the present invention has advantages of significant synergy, resistance delaying and the like, and can be used for prevention and control of a variety of pests. The compound I is defined in the instruction.