The invention discloses a method for efficiently preventing and removing weeds in a rice field, which comprises the following steps: S1, a killing stage: 7-10 days before plowing and harrowing the rice field, sterilant herbicides
glyphosate and
glufosinate-
ammonium need to be used to comprehensively and thoroughly remove worst weeds around ridges so as to prevent the worst weeds from growing from the edges of the ridges to the middle of the rice field after
sowing; and S2, a sealing and killing stage: 3-5 days after
sowing in the rice direct
sowing field, sealing herbicides
bensulfuron methyl, pretilachlor and a safener are comprehensively sprayed for one time for sealing, and the step requires no omission, so that the purpose of sealing and killing
weed seeds is achieved, and
germination of the
weed seeds is prevented. S3, when the seedlings grow to 3 leaves, 1 core and 6 leaves,
moisture in the field is drained in sunny and windless days, and then herbicides with different components are selected for supplementary killing according to the types of weeds in the rice field, compared with the prior art, the scheme is more comprehensive, targeted, flexible, safe and efficient, the cost and the risk are reduced, and better
technical support is provided for farmers.