78 results about "Quechers" patented technology

The invention relates to a full-automatic QuECHERS experimental device, and relates to the technical field of sample pretreatment, the full-automatic QuECHERS experimental device comprises an extraction unit and a pipetting unit, the extraction unit comprises: a first tube rack module comprising a plurality of test tube racks; a carrying mechanical arm; the first cap screwing module comprises a tube cap clamping and lifting assembly acting on a tube cap, a tube body clamping and rotating assembly acting on a tube body and a first sliding rail assembly for conveying a test tube to a next station; the sample adding module comprises a homogeneous proton adding module and a salt pouring module; the second cap screwing module comprises a pipe body clamping and rotating assembly, a pipe cap clamping and lifting assembly and a second sliding rail assembly for realizing communication and conveying of the extraction unit and the pipetting unit; the invention discloses a pipetting mechanical arm and a gun head frame. The device is provided with the extraction unit capable of synchronously performing extraction operation and the pipetting unit capable of performing pipetting operation, so that the extraction operation and the pipetting operation are synchronously performed during pesticide residue inspection, and the experimental efficiency and the applicability of the device are effectively improved.

The invention relates to a UPLC-MS / MS (Ultra Performance Liquid Chromatography-Mass Spectrometry / Mass Spectrometry) detection method for simultaneously determining 150 stimulant substances in cosmetics, and belongs to the technical field of stimulant detection. According to the detection method, a solid-phase extraction and QuECHERS combined pretreatment technology is adopted, firstly, an acetonitrile ultrasonic extraction mode in a QuECHERS method is adopted, secondly, a matrix is purified in a solid-phase extraction mode, an extraction tube adopts a filter type solid-phase extraction column, namely an Agilent Captiva EMR-Lipid filter column, different from a traditional HLB solid-phase extraction column, the filter column does not need to be activated and balanced, and the detection method is simple and convenient to operate. Gravity self-elution can be achieved in the sample purification process, and only 20% of pure water needs to be added into an extracting solution to achieve the purpose of activating a filtering column; and water can also be used as a dispersing agent and an impurity removing agent at the same time, so that impurities dissolved in water can be adsorbed while the sample is dispersed. The detection method provided by the invention can realize LC-MS / MS determination of 150 stimulant substances in cosmetics under the condition of simultaneously satisfying a pretreatment method for extracting 150 stimulant substances in cosmetics.

The invention provides a QuEChERS-LC-MS / MS. The method for simultaneously determining various mycotoxins in Sichuan pepper based on QuEChERS-LC-MS / MS. The method specifically comprises the following steps: S1, crushing dry Sichuan pepper, sequentially adding ultrapure water, an extracting agent and a salting-out agent, and centrifuging to take supernate, so as to obtain pretreated Sichuan pepper extract; s2, adding the pretreated zanthoxylum bungeanum extracting solution into a purifying agent, performing vortex and centrifugation, taking supernate, and filtering to obtain a purified to-be-detected sample; s3, preparing fungaltoxin mixed standard solutions with different concentrations, and drawing a standard curve; and S4, determining the content of various fungaltoxins in the pepper by adopting a liquid chromatography-tandem triple quadrupole mass spectrometer. The determination method provided by the invention is convenient, simple and accurate, can effectively extract, purify and detect various mycotoxins in Sichuan pepper, and realizes high-throughput detection of 12 mycotoxins in dry red Sichuan pepper and dry green Sichuan pepper.

The invention relates to the technical field of food safety detection, discloses a method for determining 5 new pesticide residues in animal-derived foods by gas chromatography-tandem mass spectrometry, optimizes a beef sample pretreatment method based on QuEChERS by orthogonal experimental design, adopts a detection method of gas chromatography-tandem mass spectrometry, and combines external standard method quantification to establish a detection method for detecting 5 pesticide residues in animal-derived foods, which provides certain data support for future animal-derived food supervision and import and export risk monitoring. The method comprises the following steps: 1) preparation of standard solution: respectively preparing a standard reserve solution, a mixed standard working solution and a blank matrix mixed standard working solution; 2) sample pretreatment: placing the sample in a centrifuge tube, vortexing and centrifuging with an extraction solvent and an extraction dispersant, obtaining an upper organic phase, further vortexing and centrifuging in a centrifuge tube containing a dSPE mixture to obtain a supernatant, and filtering for standby use; 3) performing GC-MS / MS analysis on the filtered supernatant.

The invention discloses a multi-dimensional high-precision detection method and system for biotoxins in agricultural products, and the method comprises the steps: carrying out sterile collection and grading pretreatment on an agricultural product sample to obtain a homogenized sample; extracting the homogenized sample by adopting a mixed solvent system, adding an internal standard substance, carrying out salting-out layering, and collecting supernate; sequentially carrying out QuEChERS purification, multi-mechanism adsorption column purification and molecularly imprinted polymer specific enrichment on the supernate; carrying out dual-mode detection on the target toxin enrichment liquid, respectively carrying out quantitative detection by adopting a liquid chromatography-tandem mass spectrometry method, and carrying out screening detection by adopting an intelligent electrochemical sensing method; performing optimization processing on the dual-mode detection signal, and comprehensively judging a sample detection result; through integrated application of a triple purification mechanism, a dual-mode detection system, machine learning signal analysis and a full-chain quality control technology, efficient enrichment and deep interference removal of target toxins in a complex matrix can be realized, and both precision and applicability are considered.

The invention relates to the technical field of pesticide residue detection, in particular to a detection method for determining benfuracarb, carbosulfan and metabolites thereof, which comprises the steps of sample preparation and preservation, sample extraction, purification, standard working curve drawing and result calculation. An optimized QuEChERS pretreatment method is adopted, a citric acid buffer salt system is combined to adjust the pH value, a liquid chromatography-mass spectrometry / mass spectrometer is used for detection, and an external standard method is used for quantitative analysis. The method can effectively solve the problem that the target object is unstable under the acidic condition, simplifies the operation process, reduces the reagent consumption, is environment-friendly, enhances the detection applicability of the method in various matrixes, is suitable for rapid detection of large-batch samples, and has the characteristics of high efficiency, accuracy and environment friendliness.

The present invention provides a method for quickly extracting and purifying pyrethroid pesticide residues from vegetables and fruits, and relates to the technical field of agricultural product safety detection. The detection method comprises S1. extraction: weighing homogenized vegetable and fruit samples into a centrifuge tube, adding 0.1% acetic acid acetonitrile for extraction, and then adding sodium chloride and sodium citrate dihydrate to obtain a supernatant. S2. solvent conversion: transferring a suitable volume of supernatant into a conical flask, vacuum rotary evaporation to near dryness, drying with nitrogen, adding n-hexane to dissolve, covering the bottle with a stopper and shaking well, and waiting for QuEChers purification; S3. purification: transferring the n-hexane solution obtained by the S2 solvent conversion to a centrifuge tube containing PSA and tungsten disulfide nanomaterials, shaking and centrifuging, taking the supernatant through an organic microporous filter membrane, and providing GC-ECD determination. The detection method effectively removes impurities in the extraction solution and has a simple procedure, shortens the sample pretreatment time, reduces matrix interference, and improves the accuracy of the determination.

The invention discloses an attapulgite-multi-walled carbon nanotube purification material as well as a preparation method and application thereof. The attapulgite-multi-walled carbon nanotube is used as a purifying agent in tea pesticide detection, matrix interferents can be effectively removed, the surface area of the attapulgite-multi-walled carbon nanotube is large, and pigments can be adsorbed from a complex matrix through the electron interaction and hydrophobic interaction of the multi-walled carbon nanotube; the porous structure of the attapulgite can physically adsorb and capture macromolecular impurities (such as proteins and polysaccharides), and amido bonds on the interface of the attapulgite-multi-walled carbon nanotubes can also adsorb polar molecules (such as organic acids). The attapulgite-multi-walled carbon nanotube interface is connected through a chemical bond, so that the phase separation problem of a physical mixed adsorbent is avoided, the material is uniformly dispersed in a solvent and can be in rapid contact with a matrix, and the purification efficiency is improved. Compared with a traditional QuEChERS method, the method has the advantages that a single material attapulgite-multiwalled carbon nanotube is adopted as a purifying agent, matrix impurities can be efficiently removed without multi-material combination, and the method is small in dosage, high in adsorption capacity, simple in experimental operation and low in raw material cost.

The invention discloses a sampling device for the content of a growth regulator in fruits and a synchronous sampling detection method, and aims to establish a rapid, simple, safe, reliable and high-specificity sampling detection method for multi-component PGRs in plant-derived food, improve the detection efficiency and reduce the detection cost, and by establishing a QuEChERS sample pretreatment method and combining an HPLC-MS detection technology, the content of a growth regulator in the fruits can be detected, and the content of the growth regulator in the fruits can be detected. According to the present invention, the combination of MgSO4, PSA, C18 and other purification materials is optimized, the PGRs residue rapid detection is performed in the fruit agricultural product matrix, the reference basis is provided for the related food quality safety supervision work such as multi-component PGRs residue detection, risk evaluation, standard formulation and the like, the sampling device can achieve the multi-point rapid equivalent sampling when the fruit is sampled, and the sampling efficiency is improved. Errors caused by manual sampling can be avoided, so that the detection result is more objective and accurate, and the operation is simple and convenient.

This invention discloses an integrated pretreatment tube and its working method for detecting mycotoxins in camellia milk. The pretreatment tube includes an outer tube with an outer tube cap at its top, a middle tube inside the outer tube with its top protruding from the outer tube cap and a middle tube cap at its top, and an inner tube inside the middle tube with its top protruding from the middle tube cap and its top cap. An ultrafiltration tube is located inside the inner tube, with its outer sidewall conforming to the inner sidewall of the inner tube, and its bottom forming an ultrafiltration element. At least one set of micropores is provided on the sidewall of the middle tube, and a first microporous filter membrane covers these micropores. At least one set of micropores is also provided on the sidewall of the inner tube, and a second microporous filter membrane covers these micropores. Through holes are provided on the sidewall of the ultrafiltration tube, and these through holes are directly opposite the positions of the second microporous filter membrane. A QuEChERS reagent pack is located at the bottom of the middle tube, and a salt pack is located at the bottom of the outer tube.

The invention discloses a QuEChERS-high performance liquid chromatography determination method for diarrheogenic illegal additives in food, and the method comprises the following steps: step 1, taking 2.0 g of a food sample, adding 10 mL of an extraction solvent, carrying out vortex oscillation-ultrasonic treatment, then adding anhydrous magnesium sulfate and sodium chloride, carrying out vortex mixing, carrying out centrifugal treatment, and extracting a supernatant; 2, taking 5mL of the supernate, adding the supernate into a purification tube containing purification salt, carrying out vortex oscillation-centrifugal treatment, taking the supernate, and enabling the supernate to pass through a 0.45 mu m polytetrafluoroethylene microfiltration membrane, so as to obtain a solution to be detected; and 3, injecting the solution to be detected into a high performance liquid chromatograph, carrying out gradient elution by adopting a C18 chromatographic column and taking acetonitrile-water as a mobile phase at a flow rate of 1.0 mL / min, a column temperature of 30 DEG C, a detection wavelength of 210 nm and a sample size of 10 [mu] L, and quantitatively analyzing a target compound through an external standard method. The invention aims to obtain a method for detecting illegal additives in food, which is low in cost and high in detection efficiency.

The invention discloses a non-targeted screening method for pesticide and veterinary drug residues in raw milk based on LC-TOFMS (liquid chromatography-time of flight mass spectrometry) and application of the non-targeted screening method, and belongs to the technical field of food safety detection. According to the method, a QuEChERS technology is adopted to carry out pretreatment on a raw milk sample, a liquid chromatography-time-of-flight mass spectrometry technology is utilized to carry out detection, and a self-built mass spectrometry database is combined to realize non-targeted qualitative screening. A self-established mass spectrum database comprises precise mass numbers, retention time, parent ion loading modes and secondary mass spectrum fragment information of 46 kinds of pesticides and 54 kinds of veterinary drugs. The method is simple in pretreatment, high in detection speed, wide in coverage range and suitable for rapid screening and quality monitoring of pesticide and veterinary drug residues in raw milk, and has good practicability and popularization value.

The invention discloses a method for detecting nitrofuran metabolites in macrobrachium rosenbergii based on UPLC-MS / MS (Ultra Performance Liquid Chromatography-Mass Spectrometry / Mass Spectrometry) and application of the method, and belongs to the technical field of safety evaluation and detection of aquatic products. According to the method, a macrobrachium rosenbergii sample is pretreated by utilizing a QuECHERS method, nitrofuran metabolites are extracted, and the method comprises the steps of adding acidified acetonitrile for extraction, adding ammonium acetate and sodium chloride for water removal, adding a dispersed solid extraction column for reducing a matrix effect and the like. After the treatment by the QuECHERS method disclosed by the invention, the obtained nitrofuran metabolite does not need to be subjected to a derivatization procedure, and an HILIC hydrophilic chromatographic column can be directly used for carrying out liquid chromatography-mass spectrometry analysis in a positive ion mode so as to detect the nitrofuran metabolite such as semicarbazide and the like. The detection method provided by the invention has the advantages of high sensitivity, strong accuracy, wide applicability and the like, and compared with the traditional detection method, the reagent waste can be avoided, and a large amount of time can be saved.

The invention belongs to the technical field of pesticide residue detection, and relates to a method for detecting residues of four herbicides in farmland soil through QuEChERS pretreatment-high performance liquid chromatography-tandem mass spectrometry. The method comprises the following specific steps: (1) drawing a standard curve: preparing a mixed standard solution of four pesticides including topramezone, bicyclopyrone, isoxaflutole and dicarfentrazone, carrying out high performance liquid chromatography-tandem mass spectrometry analysis, and drawing the standard curve according to the concentrations of the four pesticide standard solutions and quantitative ion pair peak areas; (2) QuEChERS pretreatment: performing solvent extraction, salt extraction and purifying agent treatment on to-be-detected soil to obtain a to-be-detected sample solution; and (3) analyzing the concentration of the pesticide residues: performing high performance liquid chromatography-tandem mass spectrometry analysis on the sample solution to be detected, and calculating to obtain the concentration of the four pesticide residues in the soil to be detected. The method is simple in pretreatment, high in detection recovery rate, good in detection result repeatability and high in detection sensitivity.

The application discloses a pesticide detection method for rice based on QuEChERS and ultraviolet-visible spectrophotometry, and takes three pesticides, i.e., bensulfuron-methyl, propanil and cypermethrin, as examples to carry out research on a rapid screening method for multiple pesticide residues in rice. The improved QuEChERS method is used to process rice to obtain a matrix liquid, matrix standard solution and solvent standard solution are prepared, the quantitative linear range of each pesticide and the matrix effect are obtained. In the quantitative concentration range, mixed solutions of the three pesticides in four combinations are prepared, the types of the pesticides in the rice are determined through support vector machine qualitative analysis, and the concentrations of the pesticides are predicted through partial least squares regression analysis, so that the pesticide residues in the rice can be effectively and rapidly detected.

The utility model discloses a QuECHERs sample purification column, and relates to the technical field of QuECHERs sample purification, the QuECHERs sample purification column comprises a main column body and a supporting assembly, the upper end of the main column body is connected with a sealing column cover, the supporting assembly is arranged outside the main column body, and the supporting assembly comprises a vertical sliding groove, a transverse sliding groove, a limiting sliding block, a mounting ring and a supporting column rod, transverse sliding grooves are formed in the two ends of the exterior of each vertical sliding groove, limiting sliding blocks are connected into the vertical sliding grooves, mounting rings are arranged outside the limiting sliding blocks, supporting column rods are additionally arranged on the two sides of the exterior of each mounting ring, and a purification assembly is arranged in the main column body and comprises a copper catalyst layer, a molecular sieve layer, an activated carbon layer and a microfiltration membrane layer. A molecular sieve layer is arranged below the copper catalyst layer, and an activated carbon layer is arranged below the molecular sieve layer. According to the QuECHERs sample purification column, the purification column can be stably and vertically placed on a table top, and the flexibility and motility of the purification column in the using process are improved.

The present invention discloses a method for detecting the content of phenidone in aquatic products, comprising the following steps: (1) dissolving phenidone in methanol to prepare standard solutions of different concentrations; (2) mixing the sample with acetonitrile, grinding and centrifuging to obtain a first supernatant; (3) placing the first supernatant in a flask containing PSA, C 18 and MgSO4 in a QuECherS purification tube, oscillated and centrifuged to obtain a second supernatant; (4) filtering the second supernatant through an organic filter membrane to obtain a sample solution; (5) respectively sending the standard solution and the sample solution to a high performance liquid chromatography tandem mass spectrometer for detection, and then comparing the obtained detection results to perform qualitative and quantitative detection. The present invention has simple pretreatment, accurate quantitative determination, and high sensitivity. The detection limit of phenidone is 5.0 μg / kg, and it can quickly and highly sensitively perform qualitative and quantitative detection of the phenidone content in aquatic products.

The invention provides a method for detecting imidazolone compounds in animal-derived food, and relates to the technical field of analysis and detection. The QuEChERS method is combined for extraction, the acetic acid-acetonitrile solution serves as an extracting agent, the sodium citrate dihydrate, the disodium citrate sesquihydrate, the anhydrous magnesium sulfate and the sodium chloride serve as QuEChERS extracting salt, and the extraction rate of imazamox, imazapic, imazapic, imazalic acid and imazethapyr is high. The extracting solution is purified by using a PPR phospholipid-removing solid-phase extraction small column, and the extracting solution of a high-fat food sample is frozen, so that the matrix effect is greatly reduced. High performance liquid chromatography-tandem mass spectrometry is adopted for detection, and the sensitivity of the detection method is high. The detection method provided by the invention is simple to operate and low in pretreatment cost.

The invention discloses an FM550 in-vivo enrichment detection method and a risk monitoring method for tilapia, and relates to the technical field of ecological monitoring. The method not only can reflect the actual risk of a flame retardant in the environment, but also can be conveniently applied to aquaculture and ecological risk assessment. The detection method comprises the following steps: obtaining a liver sample and a muscle sample of a target tilapia mossambica, freeze-drying the liver sample and the muscle sample for 72 hours, and crushing and homogenizing 1 g of the liver sample and the muscle sample for later use; the target tilapia mossambica refers to tilapia mossambica which is exposed in an FM550 environment within 56 days; and carrying out solvent extraction, QuEChERS purification treatment and solvent conversion treatment on the crushed and homogenized sample, and then carrying out gas chromatography-mass spectrometry detection to obtain a detection result of FM550 in-vivo enrichment.

The invention provides a method for rapidly detecting bifenthrin in drug soil barrier soil based on a QuEChERS method in combination with ultra-high performance liquid chromatography. The method comprises the following steps: step 1, preparing a soil sample to be detected; step 2, extraction; step 3, purifying; step 4, detecting; 5, preparing a standard solution; 6, drawing a correction curve; step 7, combining calculation, adopting an external standard method for quantification, substituting the corresponding peak area into a correction curve formula for calculation, and obtaining the corresponding bifenthrin concentration; the method is easy and convenient to operate, the requirement for the operation proficiency degree is low, and operation can be completed without long-time training and high operation skills; a chlorine-containing solvent is not used, so that the environmental pollution is small, the problem that a great deal of time is consumed for cleaning experimental vessels for multiple times in an oscillation extraction method is solved in the aspects of experimental preparation, vessel cleaning and the like, and the working intensity is reduced; and the concentration of bifenthrin can be rapidly, simply and accurately detected.

The invention discloses a method for determining N-nitrosamine compounds in animal-derived food, and belongs to the field of food detection. The method comprises the following steps: freezing and grinding animal-derived food, mixing the animal-derived food with an internal standard solution, deionized water and acetonitrile, and freezing and preserving to obtain a pretreated sample; the method comprises the following steps: treating a pretreated sample through a QuEChERS salt bag, centrifuging, carrying out nitrogen blowing concentration, and mixing with deionized water to prepare an enriched solution; purifying the enriched solution by adopting a purification bag or specific functional resin, and centrifugally filtering to obtain a sample solution; and calculating the content of the target compound through a peak area ratio by using a liquid chromatograph-high resolution mass spectrometer provided with an APCI source and taking N-nitrosodimethylamine-D6 as an internal standard. The functional resin is formed by cross-linking specific functional monomers and is large in specific surface area and high in adsorption selectivity; the method has strong anti-interference capability, and can efficiently detect the N-nitrosamine compounds in dried aquatic products and other animal-derived foods.

The invention relates to a method for determining halauxifen-methyl, prothioconazole and metabolite residues of halauxifen-methyl, prothioconazole and metabolite residues of halauxifen-methyl, prothioconazole and metabolite residues of halauxifen-methyl, prothioconazole and metabolite residues of halauxifen-methyl, prothioconazole and metabolite residues of halauxifen-methyl, prothioconazole and metabolite residues of halauxifen-methyl in food. The method is simple, convenient and rapid to operate, good in precision and recovery rate, and suitable for confirmed quantitative determination of halauxifen-methyl, prothioconazole and metabolite thereof in food.

The utility model relates to an efficient purification device based on a QuEChERS method, and belongs to the technical field of sample pretreatment, the efficient purification device comprises a purification pipe filled with an adsorbent, the bottom of the purification pipe is provided with a microfiltration membrane, and the purification pipe is detachably provided with a piston rod. The method has the advantage of improving the sample purification efficiency.

The invention discloses a method for rapidly screening 25 environmental hormones in an aquatic product. The method comprises the following steps: performing QuEChERS extraction on the aquatic product to obtain a QuEChERS extracting solution; mixing the QuEChERS extracting solution with an extracting agent, water and an adsorbent to form a micro-emulsion system, centrifuging the micro-emulsion system, and enriching a target object in a solidified organic phase; carrying out gradient elution separation by adopting a C18 chromatographic column; and high-resolution mass spectrum data is acquired in a positive and negative ion switching mode. The method disclosed by the invention integrates efficient extraction, deep purification and high-sensitivity detection, and is suitable for efficient enrichment, purification and accurate detection of multi-component trace pollutants in a complex biological matrix.

The invention relates to the technical field of food safety detection, and discloses a method for detecting five novel pesticide residues in a fruit and vegetable matrix by combining a QuEChERS technology with gas chromatography-triple quadrupole mass spectrometry. According to the method, a QuEChERS technology is combined with a gas chromatography-triple quadrupole mass spectrometry method to detect the content of the diflufenican, the ipfencarbazone, the oxathiazil, the cyclopyridazinate and the pethoxamid in the fruit and vegetable matrix. The method is simple, convenient, rapid and high in accuracy and precision, and provides technical support for daily detection of fruit and vegetable products; comprising 1, sample pretreatment: weighing a proper amount of a fruit and vegetable sample, and treating the fruit and vegetable sample with an extraction solvent, a water removal agent, an extraction salt and a cleaning agent to obtain a to-be-detected sample filter residue, 2, solution preparation: respectively preparing a required standard stock solution, a mixed standard working solution and a blank matrix standard solution, and 3, detecting the to-be-detected sample filter residue or / and the blank matrix standard solution.

The invention relates to a detection method for extracting triazole fungicide pesticide residues in water by using a hydrophobic deep-eutectic solvent. The detection method comprises the following steps: firstly, preparing the hydrophobic deep-eutectic solvent by using a heating method; determining the types of the deep eutectic solvents (DESs) and the proportion of hydrogen bond donors / acceptors (HBD / HBA) through a single factor experiment so as to screen out the DESs with the optimal extraction efficiency; the extraction process conditions of the QuEChERS method are optimized through an L9 (33) orthogonal experiment; inspecting the sensitivity, the detection limit, the accuracy and the precision of the method through a method verification experiment; and finally, carrying out actual sample detection. According to the method, detection can be completed in a short time with relatively high extraction efficiency and sensitivity, pretreatment operation steps are simplified, the detection cost is reduced, and potential risks of a traditional organic solvent on human health and environment are reduced.

The invention belongs to the technical field of analytical chemistry and food / traditional Chinese medicine safety detection, and particularly relates to a magnetic dispersive solid-phase extraction material and a preparation method and application thereof. The preparation method of the magnetic dispersion solid-phase extraction material comprises the following step: preparing the magnetic dispersion solid-phase extraction material Fe3O4 (at) MWCNT (at) Uio-67 from a Fe3O4 (at) MWCNT magnetic composite material by adopting an in-situ growth method. The material has ultrahigh specific surface area, rich adsorption sites and good magnetic separation characteristics, can be used in a QuEChERS pretreatment method, realizes rapid, sensitive and accurate detection of mycotoxin based on an ultra-high performance liquid chromatography-tandem mass spectrometry analysis method, and provides reliable technical support for quality safety control of related products.

The invention belongs to the technical field of detection, and particularly relates to a method for detecting various pesticide residues in corn based on magnetic aminated multi-walled carbon nanotubes. According to the invention, magnetic aminated multi-walled carbon nanotubes (m-M) are prepared from aminated multi-walled carbon nanotubes to serve as a purification material to improve a QuEChERS method, and meanwhile, the method for detecting multiple pesticide residues in corn is established by combining with UPLC-MS / MS (Ultra Performance Liquid Chromatography-Mass Spectrometry / Mass Spectrometry). The method has the advantages of high recovery rate, simplicity in operation, high precision and high accuracy, and 45 pesticide residues in corn can be simultaneously analyzed. Compared with a traditional QuEChERS purification material, the m-M can achieve an ideal purification effect without being combined with other purification materials, solid-liquid rapid separation can be achieved by applying an external magnetic field, purified liquid is obtained, the operation time is saved, the analysis efficiency is improved, and the method is suitable for rapid detection of a large number of samples.

The invention discloses a method for rapidly detecting sulfonamides in meat by an improved QuEChERS combined enzyme inhibition colorimetric method, which uses a natural eutectic solvent instead of a toxic organic solvent as an extraction agent, reduces the harm to the environment and human body, improves the extraction efficiency, and is beneficial to protecting the enzyme activity, so that the detection is more sensitive and stable; the magnetic COF (TpPa-Cl) coated Fe3O4 synthesized by adopting a simple and rapid stirring method not only has good chemical stability and can be repeatedly used, but also has excellent adsorption capacity and strong magnetism, and when the magnetic COF (TpPa-Cl) coated Fe3O4 is used as an adsorbent for improving QuEChERS, interfering substances in a sample can be effectively removed in a small amount, the pretreatment time is shortened, and the purification process is simplified; in the enzyme inhibition colorimetric detection process, a digital image colorimetric method of a smart phone is combined for quantitative analysis. The whole method has the remarkable advantages of greenness, high efficiency, short time consumption, low cost, simplicity in operation, high sensitivity and the like.

1. The name of the product of this design: Solid Phase Extractor (QuEChERS). 2. Purpose of this design product: This design product is used for solid phase extraction instrument, which is used for fully automatic operation of solid phase extraction process. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: Stereoscopic drawing 1.