55802results about How to "Improve applicability" patented technology

This disclosure provides several methods to generate nucleic acid mutations in vivo, for instance in such a way that no heterologous sequence is retained after the mutagenesis is complete. The methods employ integrative recombinant oligonucleotides (IROs). Specific examples of the described mutagenesis methods enable site-specific point mutations, deletions, and insertions. Also provided are methods that enable multiple rounds of mutation and random mutagenesis in a localized region. The described methods are applicable to any organism that has a homologous recombination system.

The present invention involves a blood pump having a pump housing with an internally disposed rotor that collectively provide a dual inflow capability which prevents thrombus formation and reduces hemolysis during use.

A method of enrolling voice information of an individual in a repository is disclosed. The individual may be associated with a contributing entity and the repository may be used by multiple entities within a consortium for creating, accessing or enhancing one or more forms of utterances associated with an individual. The method comprises establishing a predefined certification process for enrollment by multiple contributing entities of individual voice information in a repository, capturing one or more utterances from an individual associated with a contributing entity while the individual communicates over a network and storing one or more forms of the captured utterance associated with the individual along with information identifying the contributing entity associated with the individual in the repository.

The present invention relates to new adjuvants and the uses in pharmaceutical compositions, like in vaccines. In particular, the present invention provides new compounds useful as adjuvants and/or immunomodulators for prophylactic and/or therapeutic vaccination in the treatment of infectious diseases, inflammatory diseases, autoimmune diseases, tumors, allergies as well as for the control of fertility in human or animal populations. The compounds are particularly useful not only as systemic, but preferably as mucosal adjuvants. In addition, the invention relates to its uses as active ingredients in pharmaceutical compositions.

A method, according to one embodiment, includes writing a plurality of shingled tracks using an array of writers, determining first and second positions of an array of readers relative to the shingled tracks, the first and second positions being above and/or beyond track edges of the shingled tracks, repositioning the array of readers to various locations between the first and second positions and reading data from the shingled tracks, determining a read offset point where read performance is about the highest during the reading performed when repositioning the array of readers between the first and second positions, and computing, using the read offset point, data describing a lateral writing position to use during writing such that shingled tracks are written in a location specified by a format. Other systems, methods, and computer program products are described in additional embodiments.

The invention discloses an internet-of-things based medical management monitoring system. The system comprises user terminal equipment worn on a patient and a server for realizing management monitoring, wherein the user terminal equipment is communicated with the server through a wireless network; the user terminal equipment comprises a physiological parameter sensor for detecting a physiologicalparameter of the patient, an input module for inputting disease state data of the patient and a first wireless transmitting and receiving module for transmitting the physiological parameter or the disease state data to the server and receiving a diagnosis instruction of the server; and the server comprises a second wireless transmitting and receiving module for receiving the data transmitted by the user terminal equipment and transmitting the diagnosis instruction to the user terminal equipment, a remote diagnosis module for remote diagnosis of a doctor and an alarm processing module for comparing according to the detected physiological parameter of the patient and a set physiological parameter threshold and giving out an alarm. By using the system, the physiological condition of the patient can be monitored in real time; and the system has high intelligence and high practicability.

The invention discloses a multicarrier system under large bandwidth and a transmission method of correct/incorrect response information thereof. The multicarrier system consists of a base station and a terminal, wherein the base station indicates downlink allocation indexes on a physical downlink control channel; and the terminal transmits the correct/incorrect responses information in terms of a binding or multiplexing manner allocated to the terminal by the base station on the physical uplink shared channel or the physical uplink control channel according to the received downlink allocation indexes, actually-detected component carrier amount and the correct/incorrect responses information corresponding to each code stream transmitted by the physical downlink shared channel of the downlink component carrier obtained from physical downlink shared channel detection. When the incorrect response information is transmitted, the reason to the incorrect response information is indicated to the base station according to the binding or multiplexing mode allocated to the terminal by the base station. The invention can realize transmission of the correct/incorrect response information under the condition that downlink allocation information is probable to lose.

There is disclosed a resist composition comprising, at least, a polymer including repeating units represented by the following general formula (1). There can-be provided a resist composition that has a good barrier property against water, prevents resist components from leaching to water, has high receding contact angle against water, does not require a protective film, has an excellent process applicability, suitable for the liquid immersion lithography and makes it possible to form micropatterns with high precision.

The present invention provides a composition for an oily foamable aerosol, characterized in that the composition comprises a fat or oil, and a polyglycerol fatty acid ester and/or an organic and fatty acid esters of glycerol; and an aerosol comprising the composition as defined in above and a propellant.

Embodiments of the invention relate to a determination method and apparatus for poses of a mobile robot. The method comprises the following steps: when the pose of the mobile robot changes, calculating the first pose of the mobile robot in a global map by using an inertial navigation sensor; establishing a local map of a surrounding environment where the mobile robot is located by using a laser scanner in virtue of SLAM technology; subjecting the local map to image matching in the global map so as to obtain the second pose of the mobile robot in the global map and matching credibility, wherein the second pose is an optimal pose of the mobile robot in the global map obtained through image matching; and determining the pose of the mobile robot to be the first pose or the second pose according to matching credibility. According embodiments in the invention, determination of the poses of the mobile robot can be improved, and errors in pose determination can be reduced.

In the invention, the only information depended on by the segmentation is the motion vector field based on 4*4 block uniform sampling and extracted from the H.264 video signals. In the first, the normalization is made for the motion vector field of continuous multi frames, and the iteration back-projection is made for the motion vector field in order to get the accumulated motion vector field used for enhancing the salient motion vector; then, making global motion compensation for the accumulated motion vector field, and meanwhile using fast region-growing algorithm to segment it into multi regions according to motion similarity. By the invention, a computer with 3.0 GHz CPU main frequency and 512M memory can smoothly process the CIF format video sequence and play video stream in 25 fps with good segmentation quality. The invention can also be used in motion object segmentation of MPEF compressed domain.

The invention relates to the field of bio-materials, and especially relates to an acellular matrix repairing gel and a new method for preparing the same. The invention discloses the acellular matrix repairing gel and the method for preparing the same, wherein the method includes steps of acellular treatment and gelatinization treatment on tissue and organs from mammal animals to prepare the acellular matrix repairing gel. The acellular matrix repairing gel is eliminated in immunogenicity of heterologous and foreign tissue, so that activity of extracellular matrix components of the tissue is maintained as more as possible. The gel can specially repair damaged tissue and organs of human body, is strong in applicability, is suitable for requirements of various irregular-shaped repair zones and different position environments in body and has a huge clinical value.

The invention relates to an adaptive extraction and diagnosis method for degree features of a mechanical fault through a stack-type sparse automatic coding depth neural network, and belongs to the technical field of mechanical equipment state monitoring and reliability evaluation. The method aims at a problem of intelligent diagnosis of the degree of the mechanical fault, and comprises the steps: carrying out the stacking of sparse automatic coding, adding a classification layer, and constructing the stack-type sparse automatic coding depth neural network which integrates the adaptive learning and extraction of the degree features of the fault and fault recognition; employing the advantage that the sparse automatic coding can automatically learn the internal features of data, and adding noise coding to be integrated in the sparse automatic coding for improving the robustness of feature learning; carrying out the layer-by-layer no-supervision adaptive learning and supervision fine tuning of the original input complex data through multilayer sparse automatic coding, completing the automatic extraction and expression of the degree features of the mechanical fault and achieving the intelligent diagnosis of the degree of the fault. The method is used for the diagnosis of the degree of faults of rolling bearings under different work conditions, and obtains a good effect of feature extraction and diagnosis.

A process for producing high yields of enantioselective amino acids and chiral amines by reacting a keto acid or ketone and an amino acid donor in the presence of a transaminase biocatalyst to produce a keto acid by-product and an amino acid or amine product. Further reacting the keto acid by-product with a peroxide to increase the yield of additional amino acid or amine product.

A magnetoresistance effect device including a multilayer structure having a pair of ferromagnetic layers and a barrier layer positioned between them, wherein at least one ferromagnetic layer has at least the part contacting the barrier layer made amorphous and the barrier layer is an MgO layer having a highly oriented texture structure.

The invention provides a vehicle license plate recognition method based on a video. According to the vehicle license plate recognition method based on the video, moving vehicles are detected and separated out with the vehicle video which is obtained through actual photographing by means of a camera serving as input, the accurate position of a vehicle license plate area is determined by conducting vertical edge extraction on a target vehicle image obtained after pre-processing, a vehicle license plate image is separated out, color correction, binaryzation and inclination correction are conducted on a vehicle license plate image, each character in the positioned vehicle license plate area is separated to serve as an independent character, feature extraction is conducted one each character, obtained feature vectors are classified through a classifier which is well trained in advance, a classification result serves as a preliminary recognition result, secondary recognition is conducted on the stained vehicle license plate characters according to a template matching algorithm imitating the visual characteristics of human eyes, and then a final vehicle license plate recognition result is obtained. The vehicle license plate recognition method based on the video has the advantages that hardware cost is reduced, the management efficiency of an intelligent transportation system is improved, the anti-jamming performance and the robustness are high, the recognition efficiency is high, and the recognition speed is high.