3213 results about "Glycerol" patented technology

The invention belongs to the field of skin care products, and particularly relates to an anti-wrinkle and anti-aging composition as well as a preparation method and application thereof, and the anti-wrinkle and anti-aging composition comprises neurotransmitter inhibition peptide, signal peptide, madecassoside, inositol and glycosylglycerol. The neurotransmitter inhibition type peptide is at least three of acetyl hexapeptide-8, arginine / lysine polypeptide, dipeptide diaminobutyrylbenzylamide diacetate and acetyl octapeptide-3, and the signal type peptide is at least two of palmitoyl pentapeptide-4, decapeptide-4 and acetyl tetrapeptide-9. Compared with the prior art, all the components of the anti-wrinkle and anti-aging composition act on different anti-aging pathways and can be matched with one another from multiple aspects of oxidation resistance, inflammation resistance, moisturizing, cell viability enhancement, wrinkle reduction and the like, a more comprehensive and better anti-aging effect is provided, skin aging is comprehensively resisted, the skin is in a more young state, and the anti-wrinkle and anti-aging composition has the advantages that the anti-wrinkle and anti-aging effects are achieved. And the anti-wrinkle and anti-aging composition is small in irritation and good in stability.

The application belongs to the technical field of daily chemical industry, and particularly relates to an emulsion and a preparation method thereof. The emulsion provided in the application comprises an emulsifier, glycerol, oil-phase active substance, pentaerythritol tetra(ethylhexanoate) and water; the emulsifier is a lipopeptide; the weight percentage of the lipopeptide and the glycerol is not less than 3%; the weight ratio of the oil-phase active substance and the pentaerythritol tetra(ethylhexanoate) is 1:3-10; the ratio of the sum of the weights of the lipopeptide and the glycerol to the sum of the weights of the oil-phase active substance and the pentaerythritol tetra(ethylhexanoate) is 1:3-10; and the ratio of the sum of the weights of the lipopeptide, the glycerol, the oil-phase active substance and the pentaerythritol tetra(ethylhexanoate) to the weight of the water is 1:1-4. The emulsion is prepared by using sodium bacillomycin, glycerol and pentaerythritol tetra(ethylhexanoate), can effectively inhibit the diffusion of the oil-phase active substance at the interface of the emulsion, reduce the oxidative degradation of the oil-phase active substance, and greatly prolong the effective action time of the oil-phase active substance in the emulsion.

The invention relates to the field of medical materials and medical instruments, and discloses a dry bioprosthetic valve and a preparation method thereof.The preparation method comprises the following steps that S1, pericardium and a cross-linking agent solution are mixed for a cross-linking reaction; s2, carrying out first dehydration treatment on the crosslinked pericardium by adopting a first dehydration solution with gradually increased concentration gradient under an ultrasonic condition; and S3, carrying out second dehydration treatment on the pericardium subjected to the first dehydration treatment by adopting a second dehydration solvent, so as to obtain the dried bioprosthetic valve. According to the preparation method provided by the invention, ethanol, isopropanol and water in a specific proportion are adopted to prepare a dehydration solution with gradient concentration, and two-step dehydration drying is carried out in combination with the physical effect of an ultrasonic technology and glycerol, so that rapid rehydration of the bioprosthetic valve is realized, and the original shape and mechanical property of the bioprosthetic valve can be better recovered after rehydration; and the immediate hemodynamic stability of the valve is improved.

The invention relates to the field of oral cavities, and particularly discloses a lasting antibacterial type composite tooth socket for medicine carrying and a preparation method thereof.The lasting antibacterial type composite tooth socket comprises an adsorption layer and an antibacterial membrane layer, the adsorption layer is used for adsorbing oral cavity treatment liquid medicine, and the antibacterial membrane layer comprises a nano-silver antibacterial layer and a chitosan antibacterial layer; the preparation method comprises the following steps: mixing a tea polyphenol-polylactic acid composite solution, a nano-silver-carboxylation modified cellulose compound and a polyvinyl alcohol solution, and carrying out electrostatic spinning to prepare a nano-silver antibacterial fiber membrane, so as to form the nano-silver antibacterial layer; mixing chitosan with hot water, adding cinnamyl aldehyde, glycerol and boric acid, stirring to obtain a mixed solution, coating one side of the nano-silver antibacterial layer with the mixed solution, and curing to form a chitosan antibacterial layer; the adsorption layer is attached to the side, away from the chitosan antibacterial layer, of the nano-silver antibacterial layer, and then the lasting antibacterial type composite tooth socket for carrying the medicine is prepared through hot-pressing compounding. The drug-loaded composite tooth socket has the characteristic of further improving the antibacterial property and the antibacterial durability of the drug-loaded composite tooth socket.

The invention provides a glyceryl triacetate production parameter control method and system based on reinforcement learning, and relates to the technical field of optimization control methods, and the method comprises the steps: obtaining the production parameters of glyceryl triacetate; based on the kinetic model, constructing a kinetic equation of the esterification reaction of glycerol and acetic acid; constructing a digital twinborn simulation environment of the glyceryl triacetate production process; defining a reinforcement learning framework by taking a digital twin simulation environment as a scene; according to the reinforcement learning framework, taking the Elman neural network as a state predictor, and predicting the state of the glyceryl triacetate; solving the reinforcement learning framework through an MO-MPO algorithm, and determining an optimal control strategy and an optimal production parameter sequence corresponding to the optimal control strategy; judging whether the process capability index is smaller than a process capability index threshold value or not; if yes, continuing to solve the reinforcement learning framework; otherwise, outputting an optimal production parameter sequence; and controlling the optimal production parameter sequence through a PID (Proportion Integration Differentiation) control algorithm.

The invention discloses a preparation method of an edible pectin film capable of monitoring and prolonging fruit freshness, which comprises the following steps: carrying out oxidation reaction on pectin and sodium periodate, then terminating the reaction and purifying to obtain oxidized pectin; the preparation method comprises the following steps: dissolving oxidized pectin in water, then adding histidine, and carrying out heating reaction at 60-120 DEG C for 1-3 hours to obtain a reaction product with pH-responsive fluorescence characteristics; adding a calcium chloride aqueous solution as a cross-linking agent into the reaction product, simultaneously adding glycerol as a plasticizer, stirring and mixing for 5-15 minutes at the temperature of 50-70 DEG C, and then stirring and mixing for 1.5-2.5 hours at the temperature of 20-30 DEG C to obtain a uniform film forming solution; pouring the film-forming liquid into a film, and drying to obtain an edible pectin film; the invention also provides the edible pectin film prepared by the preparation method. The prepared edible pectin film is mainly used for packaging fruits, and the freshness of the fruits can be visually displayed through fluorescence change while the fruits are kept fresh.

The invention discloses a waterproof long-lasting oil-control gel composition and a preparation method thereof, and belongs to the technical field of cosmetics. The composition comprises 4-6 parts of an oil absorption compound A, 9-13 parts of an oil absorption compound B and 70-95 parts of a gel matrix, wherein the oil absorption compound A is prepared from mesoporous silica and poloxamer 407, and the aperture of the oil absorption compound A is 5-10 nm; the oil absorption compound B is prepared from polymethyl methacrylate microspheres, isododecane and polyglycerol-3 diisostearate, and the pore diameter of the oil absorption compound B is 150 to 300 nm. According to the invention, through dual mechanisms of temperature response and volatilization driving, a dynamic gradient structure of bottom layer small aperture-surface layer large aperture is formed at skin temperature, and directional migration of grease is realized; meanwhile, the surface property transformation of the material after oil absorption is creatively utilized, a hydrophobic membrane is formed on the surface of the polymethyl methacrylate microsphere, a self-enhanced waterproof barrier is constructed, the unique effect that the more oil is absorbed, the more water is resisted is achieved, the problem of makeup removal caused by sebum and sweat can be effectively solved, and the makeup lasting time is remarkably prolonged.

The invention provides a capsule used as an aerosol generating substrate, the capsule contains fuming materials propylene glycol and glycerol, a capsule skin comprises a colloidal substance, the colloidal substance is at least one of animal glue, vegetable glue, starch and a starch modifier, and only one layer of capsule skin is provided. The invention also discloses an aerosol generating product using the capsule, and uniform and sufficient smoke release can be obtained at a lower heating temperature, so that the aerosol product can further reduce the energy consumption, reduce the release of harmful substances and improve the feeling of a smoker.

The invention relates to polyethylene glycol glycerol ricinoleate granules as well as a preparation method and application thereof. The granules comprise first polyethylene glycol glycerol ricinoleate with an HLB (Hydrophile-Lipophile Balance) value of 17-19, second polyethylene glycol glycerol ricinoleate with an HLB value of 12-14, a carrier and vitamin E acetate. According to the invention, fatty acid and / or hydrogenated vegetable oil are / is taken as a nutritional carrier, and polyethylene glycol glycerol ricinoleate with an HLB value of 12-14 is introduced, so that the dispersity of active ingredients with a high HLB value (17-19) in the carrier is effectively improved, and granulation is facilitated; meanwhile, the vitamin E acetate is added, so that the immunity of animals can be enhanced while the effects of resisting oxidation and prolonging the shelf life of the product are achieved. The granules solve the problems that pure products are not easy to mix, inconvenient to use and the like.

The invention discloses a preparation method and application of a reproducible self-healing polyurethane elastomer with synergism of dynamic silicon oxygen bonds and multiple hydrogen bonds. The method comprises the following steps: (1) carrying out a pre-polymerization chain extension reaction on polytetrahydrofuran, isophorone diisocyanate and a catalyst; (2) adding a 3, 13-dihydroxy propyl octaphenyl double-layer silsesquioxane monomer to carry out a chain extension reaction, and then adding carbohydrazide to carry out a reaction; and (3) adding glycerol and camphorsulfonic acid, uniformly stirring, pouring into a mold, curing and drying, thereby obtaining the reproducible self-healing polyurethane elastomer with synergistic dynamic silicon-oxygen bonds and multiple hydrogen bonds. According to the invention, a common fabric is soaked in a dispersion liquid formed by uniformly mixing diluted polyurethane and hydrophobically modified MXene to obtain the multifunctional composite material with the functions of self-cleaning, self-repairing, photo-thermal conversion and human body sensing.

The invention discloses an antibacterial dressing for skin repair and a preparation method thereof, and relates to the field of medical dressings. The antibacterial dressing for skin repair is prepared from the following raw materials in parts by weight: 4-8 parts of carboxymethyl chitosan, 2-5 parts of collagen, 5-10 parts of glycerol, 10-20 parts of a framework material, 1-2 parts of an antibacterial agent, 1-3 parts of a humectant and 70 parts of purified water. The prepared antibacterial dressing for skin repair has good moisturizing performance and antibacterial performance.

The invention discloses a gel composition for improving compatibility and gelling speed of a tooth whitening product. The gel composition comprises whitening gel and a catalyst, respectively filling the whitening glue and the catalyst into a double-barrel injector; when the tooth whitening gel is used, the push rod is pushed, the whitening gel and the catalyst in the double-tube barrel are squeezed out at the same time and mixed at the mixing head to form the tooth whitening gel capable of being smeared on the tooth surface of a patient, and the pH value of the tooth whitening gel is 7.5-10.0. The catalyst comprises potassium salt or strontium salt, sodium fluoride, glycerol, cross-linked polyacrylamide gels, strong alkaline substances, essence and water; the whitening gel comprises a hydrogen peroxide solution, a cross-linked polyacrylamide gel, glycerin, essence and water. The cross-linked polyacrylamide gel is adopted, the gel is resistant to strong-alkalinity and high-pH environment and various inorganic salt ions such as fluoride, sylvite or strontium salt, the prepared gel is stable in form and good in compatibility, the gel preparation process is simple, the gel is rapidly swelled when encountering water and does not huddle, and long-time standing is not needed.

The invention relates to a diacylglycerol acyltransferase capable of synthesizing triglyceride as well as a coding gene and application of the diacylglycerol acyltransferase, and belongs to the field of enzymology, the nucleotide sequence of the gene for coding the diacylglycerol acyltransferase is as shown in SEQ ID NO.1, and the amino acid sequence of the diacylglycerol acyltransferase is as shown in SEQ ID NO.2. The invention also provides a recombinant plasmid and a recombinant engineering bacterium containing the gene of the enzyme. Diglyceride and an acyl donor are used as substrates, and triglyceride is catalytically synthesized through an acyl transfer reaction by using the enzyme. The invention provides an efficient tool for realizing enzymatic biosynthesis and large-scale production of natural triglyceride.

The invention discloses an automatic treatment device and method for metal workpiece surface polishing and application. According to the automatic environment-friendly electrochemical polishing device, the workpieces are automatically transferred through the automatic conveying device, automatic connection of all the procedures is achieved, and the automatic environment-friendly electrochemical polishing process of the metal workpieces such as the pure magnesium workpieces is achieved; and compared with the prior art, only water is used as a cleaning medium in the whole process, and toxic and harmful chemical agents are not needed. The environmental pollution risk is greatly reduced, and the environmental protection requirement is met. The environment-friendly polishing solution is adopted for electrochemical polishing, core components of the polishing solution are biodegradable non-toxic reagents such as ethyl alcohol and glycerinum, waste liquid treatment is simple, zero liquid discharge can be achieved, and the difficulty and cost of waste water treatment are remarkably reduced. According to the invention, the process flow is simplified, the consumption of chemicals and pollution emission are reduced, and the process efficiency is improved. According to the invention, whole-process monitoring and automatic operation from pretreatment to post-treatment are realized, the production efficiency and consistency are improved, and the method is suitable for industrial large-scale application.

The invention belongs to the technical field of cosmetics, and particularly relates to a water-in-oil-in-water three-phase coated microbead as well as a preparation method and application thereof. The water-in-oil-in-water three-phase coated microbead is of a spherical structure and sequentially comprises an outer water phase, an inner oil phase and an inner water phase from outside to inside, the outer water phase comprises sodium alginate, agarose, cyclodextrin, glycerin and other components, the inner oil phase comprises caprylic / capric triglyceride, grape seed oil, olive squalane, tocopherol and other components, and the inner water phase comprises sodium alginate, agarose, cyclodextrin, glycerin and other components. And the inner water phase comprises ampelopsis grossedentata extract, astragalus membranacus root extract and other components. According to the invention, an easily oxidized and unstable active matter is fully and firmly protected by adopting a droplet microfluidic coating technology, so that the active matter is free from external stimulation, active ingredients with different effects play multiple roles, and the composition has good anti-inflammatory, soothing and oil-controlling effects and can be applied to the field of cosmetics.

The invention discloses a solid ultrasonic gel patch as well as a preparation method and application thereof, and belongs to the technical field of medical chemistry. The solid ultrasonic gel patch is prepared from an acrylamide monomer, polyvinyl alcohol, sodium polyacrylate, sodium carboxymethyl cellulose, nano silicon dioxide, propylene glycol, glycerol, acrylic acid, triethanolamine, a cross-linking agent, an initiator and water according to a specific ratio. The prepared solid ultrasonic gel patch is highly matched with human soft tissue in acoustic impedance (about 1.62-1.63 * 10 < 6 > Pa.s / m), low in acoustic attenuation coefficient (less than or equal to 0.034 dB / (cm.MHz)), moderate in skin adhesion, excellent in flexibility and moisture retention, capable of solving the problems that a traditional ultrasonic coupling agent is inconvenient to use, easy to dry, poor in experience and the like, and suitable for acoustic wave conduction in ultrasonic examination and treatment.

The invention discloses diglyceride prepared by an enzymic method as well as a preparation method and application thereof, and belongs to the technical field of deep processing of grease. The method comprises the following steps: adding fatty acid into a choline chloride-glycerol-urea ternary eutectic solvent, uniformly mixing, and then adding candida antarctica lipase B for esterification reaction to obtain a reaction mixture; separating the reaction mixture, and recovering an upper-layer oil phase; and separating and purifying the upper-layer oil phase to obtain the diglyceride. According to the method, the reaction rate is high, the selectivity of the diglyceride in the esterification process is high, the yield of the diglyceride can reach 65% or above by reacting for 1 h, the selectivity of the diglyceride is 75% or above, and the purity of the separated and purified diglyceride is 90% or above; in addition, the method is simple to operate, and the reaction product and the eutectic solvent can be separated through simple centrifugation after the reaction is finished; in addition, the monoglyceride content in the product is low, and the subsequent separation and purification difficulty is greatly reduced.

Disclosed is a water-in-oil type emulsion cosmetic composition comprising (a) at least one polyglycerol type surfactant; (b) a resin; (c) a solvent comprising at least one polar oil and at least one non-polar oil; and (d) water.

The invention discloses a collateral-dredging and pain-relieving gel plaster and a preparation method thereof. The collateral dredging and pain relieving ointment is prepared from the following raw materials in percentage by mass: camphor, borneol, menthol, absolute ethyl alcohol, collateral dredging and pain relieving volatile oil, a surfactant, collateral dredging and pain relieving extract, tartaric acid, purified water, partially neutralized sodium polyacrylate, a cross-linking agent, an adhesive, glycerol, EDTA-2Na (Ethylene Diamine Tetraacetic Acid) and a filling agent. The plaster disclosed by the invention is high in application comfort, breathable, free from aching feeling after being uncovered, free from residue on skin and not sticky when being in contact with sweat; the use of an organic solvent is basically avoided in the production process; the matrix contains components such as water and glycerol, has the effects of moistening the skin and promoting skin hydration, and is free of irritation and sensitization to the skin; repeated uncovering and pasting can be achieved, and the viscosity influence is small.

The invention relates to the technical field of cosmetics, and particularly discloses emulsion type foaming cleaning scrub cream with a skin care effect and a preparation method of the emulsion type foaming cleaning scrub cream. The scrub cream is prepared from the following raw material components in percentage by mass: 8 to 15 percent of glycerol, 0.2 to 0.9 percent of sodium hydroxide, 0.3 to 0.8 percent of citric acid, 0.03 to 0.2 percent of EDTA (Ethylene Diamine Tetraacetic Acid) disodium, 0.5 to 1.5 percent of an auxiliary agent, 1.5 to 3.0 percent of a thickening agent A, 1.5 to 3.0 percent of a thickening agent B, 5.86 to 1457 percent of an emollient, 12 to 22 percent of a surface active foaming agent, 0.8 to 3.0 percent of an emulsifying agent, 2.5 to 13 percent of a cutin stripping agent, 0.7 to 1.3 percent of a preservative, 0.32 to 0.92 percent of a skin conditioning agent and the balance of water, the skin conditioner is a mixture prepared from sodium hyaluronate, tocopherol, papain, nicotinamide, carnosine, panthenol and phytosterol oleate.

The invention discloses a method for producing mRNA (messenger ribonucleic acid) template plasmids by fermenting escherichia coli. When the recombinant escherichia coli is fermented and cultured, a seed solution of the recombinant escherichia coli is inoculated into a basic culture medium to be fermented and cultured until the OD600 value of fermentation liquor is 18-22, then a fed-batch culture medium is continuously added at the feeding rate of 5-15 mL / L / h to be subjected to continuous fed-batch fermentation culture, the basic culture medium contains 0.05-0.2 mmoL / L of ferric salt compound and 0.05-0.2 mmoL / L of copper chloride dihydrate, and the basic culture medium contains 0.05-0.2 mmoL / L of ferric salt compound and 0.05-0.2 mmoL / L of copper chloride dihydrate. The basal culture medium contains 10-15 g / L of copper chloride dihydrate and 100-300 mg / L of p-hydroxybenzoic acid, the carbon source of the basal culture medium contains 0.1-0.3 mmoL / L of a ferric salt compound, 0.1-0.3 mmoL / L of copper chloride dihydrate and 100-300 mg / L of p-hydroxybenzoic acid, the carbon source of the fed-batch culture medium contains 360-480 g / L of glycerol, and the ferric salt compound is one or more of ferrous citrate, ferric ammonium citrate or ferrous sulfate heptahydrate. According to the method, the yield and superhelix content of the mRNA template plasmids are improved by optimizing the culture medium formula and culture conditions, and large-scale production of the high-quality target mRNA template plasmids is facilitated.

The invention relates to the technical field of skin care products, and discloses an anti-aging and whitening composition and a preparation method thereof.The anti-aging and whitening composition comprises anti-aging and whitening components, whitening synergistic components, moisturizing and repairing components and deionized water, and the anti-aging and whitening components comprise botryine, ergothioneine and Ectoine; wherein the mass ratio of the glassine to the ergothioneine to the ectoine is (1.2 to 2.0) to (0.4 to 0.7) to (1.0 to 1.5); the whitening synergistic component comprises one or more of nicotinamide, glabridin and tranexamic acid; the moisturizing and repairing component is prepared from one or more of sodium hyaluronate, ceramide NP, glycerol and 1, 3-butanediol. Experiments show that the mass ratio of the glassine to the ergothioneine to the ectoine is (1.2-2.0): (0.4-0.7): (1.0-1.5), so that the glassine, the ergothioneine and the ectoine show a remarkable synergistic effect (in some cases, the synergistic index CIlt is 0.85), and the anti-aging and whitening functions of the composition containing the glassine, the ergothioneine and the ectoine are improved.

The preparation method comprises the following steps: mixing and stirring polyvinyl alcohol and deionized water, cooling, adding glycerol and hyaluronic acid, stirring, adjusting the pH value to be acidic, cooling, adding a modified additive, stirring, injecting into a mold, repeatedly freezing and thawing, and carrying out vacuum drying to obtain the anti-wrinkle and anti-aging polymer hydrogel mask. In the using process of the hydrogel mask, when the internal modified additive makes contact with the skin surface, due to the weak acidity of the skin, an iron organic frame structure on the surface of the modified additive is attacked by hydrogen ions, coordinate bonds of the modified additive are damaged, and a skeleton is partially or completely dissociated; the active substances can be slowly released under the action of the modified additive, advanced oxidation caused by too fast release of the active substances is prevented, and the modified additive also contains a nano silicon dioxide structure, so that the mask has certain air permeability, the strength, elasticity and toughness of the mask are improved, and the mask cloth is prevented from being easily torn.

The present invention relates to a packaged condom comprising a sealed package; and within the package, a condom comprising natural rubber latex and / or synthetic polyisoprene; wherein the condom comprises, on one or more surfaces thereof and in contact with the natural rubber latex and / or synthetic polyisoprene, an aqueous lubricant; wherein the aqueous lubricant comprises: a thickener and 5 wt.% to 30 wt.%, based on the total weight of the aqueous lubricant, of a humectant comprising at least one organic compound selected from the group consisting of glycerol, propylene glycol, polyethylene glycol, and any combination thereof; and one or more sugar alcohols having a molecular weight of from 120 to 10000 g / mol. It also relates to a method for preparing a packaged condom and to the use of an aqueous lubricant to lubricate one or more surfaces of a condom. The condom preferably presents a transparent appearance to the end user.

The present invention relates to detergents and cleaning compositions that comprise a surfactant, an anti-redeposition agent, and an effective amount of 1,2-heptanediol and / or 2,3-heptanediol or a specific type of anti-redeposition boosting agent, such as alkanediols, glyceryl caprylate, 4-hydroxyacetophenone, ethyl hexyl glycerin or tropolone, and the use of said detergents and cleaning compositions for the preparation of a detergent and cleaning product for household, institutional and industrial application. Furthermore, the present invention relates to a method of treating a stained and / or soiled substrate, using the detergents and cleaning compositions according to the present invention. Additionally, the present invention relates to the use of 1,2-heptanediol and / or 2,3-heptanediol or of specific substances as defined herein for boosting the activity of an anti-redeposition agent in a detergent and cleaning composition and / or for improving cleaning performance of a detergent and cleaning composition. Moreover, the present invention relates to a method of boosting the activity of an anti-redeposition agent in a detergent and cleaning composition and / or of improving cleaning performance of a detergent and cleaning composition by adding an effective amount of 1,2-heptanediol and / or 2,3-heptanediol or of specific anti-redeposition agents, such as alkanediols, glyceryl caprylate, 4-hydroxyacetophenone, ethyl hexyl glycerin or tropolone to said detergent and cleaning composition. Finally, the present invention relates to the use of 1,2-heptanediol, 2,3-heptanediol or a mixture comprising 1,2-heptanediol and 2,3-heptanediol or at least one anti-redeposition boosting agent, such as alkanediols, glyceryl caprylate, 4-hydroxyacetophenone, ethyl hexyl glycerin or tropolone as anti-redeposition agent.

The invention discloses a method for synergistically extracting flavonoid compounds in epimedium wushanense by combining a ternary eutectic solvent with in-situ ultrasound, which is characterized in that choline bitartrate-urea-glycerol (Chb: Ure: Gly) is used as the ternary eutectic solvent, and the flavonoid compounds in epimedium wushanense are synergistically extracted by the in-situ ultrasound. The method is high in extraction speed and good in repeatability, solvent consumption can be reduced, operation steps are simplified, and efficiency is improved.

The present application relates to the field of cosmetic technology, in particular to a quick-drying and shaping spray and a preparation method thereof, in particular to a hair styling product which is quickly dried, permanently shaped and has hair care effect through the synergistic effect of specific film-forming agents and volatile systems, comprising the following components: ethanol 30-50%, aminomethyl propanol 0.1-1%, butanediol 1-5%, octyl acrylamide / acrylate / methyl acrylate copolymer 5-15%, PEG-12 dimethicone 0.5-2%, keratin 0.1-2%, hydrolyzed keratin 0.1-2%, oxidized keratin 0.1-2%, aloe barbadensis leaf extract 0.5-3%, selaginella kurata extract 0.5-3%, radix falatoniae extract 0.5-3%, radix salviae miltiorrhizae extract 0.5-3%, water 20-40%, essence 0.1-2%, cetrimonium chloride 0.1-1%, phenoxyethanol 0.5-1.5%, propylene glycol 1-5%, p-hydroxyacetophenone 0.5-1.5%, chlorphenesin 0.1-0.5%, ethylhexylglycerin 0.5-1.5%.

A polishing liquid containing: abrasive grains; an additive; and water, in which the additive includes (A1) a polyglycerol having a weight average molecular weight of 350 to 2800 and (B) a compound having two or more nitrogen atoms to which a hydroxyalkyl group is bonded. A polishing liquid containing: abrasive grains; an additive; and water, in which the additive includes (A2) a polyglycerol having a hydroxyl value of 800 to 1000 mgKOH / g and (B) a compound having two or more nitrogen atoms to which a hydroxyalkyl group is bonded.

The invention provides an external application medicine for incontinent dermatitis and a preparation method thereof. The composition is prepared from active ingredients such as a radix sophorae flavescentis extract, calamine, vitamin E, ceramide, a herba portulacae extract, glycyrrhizic acid, chitosan and colloidal oat powder according to a specific proportion. Moisturizing matrixes such as sodium hyaluronate and glycerol and functional components such as tea tree essential oil are supplemented. And through a preparation process of matching high-speed shearing with ultrasonic dispersion, uniform dispersion and stability of each component are ensured. Experimental results show that the composition shows a remarkable synergistic effect in the aspects of anti-inflammation, antibiosis, skin barrier repair and the like, the comprehensive relieving and repairing effect of the composition is superior to that of a conventional drug control, and all the components and a special preparation process are necessary for achieving the optimal effect. The product has no irritation to human skin, is good in safety, can be prepared into various dosage forms such as cream, hydrogel or spray, and is suitable for nursing and repairing sensitive skin.

The invention discloses a colchicine external preparation with high intradermal residual quantity and percutaneous transmittance as well as a preparation method and application thereof, and belongs to the technical field of pharmaceutical preparations. The invention provides a colchicine external preparation with high intradermal residue and transdermal transmittance. The colchicine external preparation comprises: a) colchicine or a pharmaceutically acceptable salt thereof; b) a penetration enhancer; c) pharmaceutically acceptable excipients and / or excipients; the penetration enhancer is at least one of polyglycerol oleate or isosorbide dimethyl ether. The drug loading capacity and the percutaneous transmittance of the colchicine external preparation disclosed by the invention are remarkably improved. When polyglycerol oleate is selected as a penetration enhancer to prepare colchicine gel, the intradermal retention volume can reach 358.08 micrograms within 20 hours. When isosorbide monomethyl ether is selected as a penetration enhancer to prepare ethosome gel, the accumulated penetration amount can reach 106.87 mu g / cm < 2 >, and the intradermal residual amount can reach 90.58 mu g or above.