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794 results about "Triglyceride" patented technology

A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids (from tri- and glyceride). Triglycerides are the main constituents of body fat in humans and other vertebrates, as well as vegetable fat. They are also present in the blood to enable the bidirectional transference of adipose fat and blood glucose from the liver, and are a major component of human skin oils.

Pharmaceutical use of an extended-release composition containing pirfenidone for the treatment and reversal of human steatohepatitis (nafld / NASH)

PendingUS20250325530A1Organic active ingredientsDigestive systemPeroxisome ProliferationLiver fibrosis
The present invention relates to the use of a pharmaceutical composition in the form of extended-release tablets containing Pirfenidone for treating NAFLD / NASH and advanced liver fibrosis by decreased serum cholesterol and triglycerides as well as reducing the content of hepatic fat accumulation, both in the form of macrosteatosis and microsteatosis. Additionally, its use as an agonist for PPARgamma (peroxisome proliferation receptor activated gamma), PPARalpha (peroxisome proliferation receptor activated alpha), LXR and CPT1, key molecules in the metabolism of fatty degradation and inflammation of the liver. In addition, another use is the induction of decreased expression of NFKB master gene, transcriptional inducer of hepatic inflammatory process factor. All of these events results in the reversal of NAFLD / NASH and advanced liver fibrosis.
Owner:EXCALIBUR PHARM INC

Enzymatic method enriched high-purity nannochloropsis oculata polar lipid and preparation method thereof

The invention relates to the technical field of functional lipid preparation, in particular to high-purity nannochloropsis oculata polar lipid enriched by an enzymic method and a preparation method of the high-purity nannochloropsis oculata polar lipid. The method comprises the following steps: specifically and selectively hydrolyzing triglyceride by using immobilized Lip2 lipase to generate glycerol and free fatty acid, retaining and enriching polar lipid components, and carrying out centrifugal filtration and molecular distillation to obtain the high-purity nannochloropsis oculata polar lipid. The invention provides a method for preparing high-purity polar lipid by performing enzymolysis on nannochloropsis oculata oil by using lipase Lip2 produced by yarrowia lipolytica, which maximally retains the polar lipid and obtains a high-purity polar lipid product through the specific catalytic action of Lip2 lipase. The method which is mild in reaction condition, environment-friendly, simple in step and high in purity is provided for efficient enrichment of the nannochloropsis oculata polar lipid, the prepared polar lipid product is extremely high in purity, and the blank of efficient preparation of the nannochloropsis oculata polar lipid in the prior art is filled.
Owner:OCEAN UNIV OF CHINA +2

Efficient separation and purification method of MLnM type medium and long chain triglyceride

The invention discloses an efficient separation and purification method of MLnM type medium-chain and long-chain triglyceride, and belongs to the technical field of separation and purification. The efficient separation and purification method comprises the following steps: S1, preparing a crude product; s2, mixing the crude product with an adsorbent for static adsorption; and S3, performing column chromatography elution on the static adsorption product, and performing dynamic chromatography to separate the MLnM type triglyceride. According to the efficient separation and purification method of the MLnM type medium-long-chain triglyceride, a neutral aluminum oxide static adsorption and dynamic column chromatography coupling process is adopted, the purity of the MLnM type triglyceride can be greatly improved and is far higher than that of other adsorbents, the whole process steps are clear, the steps of raw material preparation, static adsorption, dynamic chromatography and the like are included, and the method is suitable for industrial production. The operation process is easy for standardized and large-scale production, and does not need to depend on complex equipment such as molecular distillation, supercritical CO2 extraction and the like.
Owner:BOHAI UNIV

Composition with functions of reducing blood sugar and blood fat as well as preparation method and application of composition

The invention belongs to the technical field of biological medicines, and particularly discloses a composition with functions of reducing blood sugar and blood fat as well as a preparation method and application of the composition. Chinese herbal compound medicinal materials are subjected to water extraction and high-temperature and high-pressure sterilization, and lactobacillus rhamnosus SHA113 bacterial sludge is resuspended in a water extract to obtain the composition of lactobacillus rhamnosus SHA113 and the Chinese herbal compound; the traditional Chinese medicine compound composition comprises astragalus membranaceus, raw Chinese yam, hawthorn, gynostemma pentaphylla, liquorice and jujube; the preservation number of the lactobacillus rhamnosus SHA113 is CCTCC (China Center For Type Culture Collection) NO: M 2017838; the lactobacillus rhamnosus SHA113 and traditional Chinese medicine compound composition can remarkably reduce the content of triglyceride and cholesterol in serum, control the fasting blood-glucose level, relieve accumulation of triglyceride and cholesterol in the liver and improve the oxidation resistance of the liver, has wide market potential and application prospects, and has wide application prospects. The compound can be applied to preparation of drugs for reducing blood sugar and blood fat.
Owner:NORTHWESTERN POLYTECHNICAL UNIV

Water-in-oil-in-water three-phase coated microbead as well as preparation method and application thereof

The invention belongs to the technical field of cosmetics, and particularly relates to a water-in-oil-in-water three-phase coated microbead as well as a preparation method and application thereof. The water-in-oil-in-water three-phase coated microbead is of a spherical structure and sequentially comprises an outer water phase, an inner oil phase and an inner water phase from outside to inside, the outer water phase comprises sodium alginate, agarose, cyclodextrin, glycerin and other components, the inner oil phase comprises caprylic / capric triglyceride, grape seed oil, olive squalane, tocopherol and other components, and the inner water phase comprises sodium alginate, agarose, cyclodextrin, glycerin and other components. And the inner water phase comprises ampelopsis grossedentata extract, astragalus membranacus root extract and other components. According to the invention, an easily oxidized and unstable active matter is fully and firmly protected by adopting a droplet microfluidic coating technology, so that the active matter is free from external stimulation, active ingredients with different effects play multiple roles, and the composition has good anti-inflammatory, soothing and oil-controlling effects and can be applied to the field of cosmetics.
Owner:CONOME (GUANGZHOU) BIOTECHNOLOGY CO LTD

Preservative sprayed before picking of peach fruits and spraying method thereof

The invention discloses a preservative sprayed before picking of peach fruits and a spraying method thereof, and is characterized in that the preservative is prepared from the following raw materials in percentage by mass: 2-8% of alginate oligosaccharide, 0.05-0.2% of gamma-aminobutyric acid, 0.5-2% of capric triglyceride, 0.1-0.3% of glycerol, 1-3% of tween-80, 0.2-1% of sodium carboxymethyl cellulose and the balance of water. The method for spraying the preservative to the peach fruits before picking the peach fruits comprises the following steps: selecting peach trees with consistent tree age and growth vigor, starting from the 90th-110th day after the peach fruits bloom, spraying the peach fruits three times every three days, uniformly spraying the surfaces of the peach fruits until the surfaces of the peach fruits are in a dripping state, and spraying the preservative to the surfaces of the peach fruits. The method has the advantages that the commodity fruit rate of the picked peach fruits is increased, the storage period of the peach fruits is prolonged, the normal-temperature storage rotting rate of the peach fruits is reduced, the cold damage caused by low-temperature storage is relieved, and the quality and taste of the fruits are kept.
Owner:NINGBO UNIV

Nutrient composition for improving muscle function and application

The invention relates to the technical field of nutritional foods, and particularly discloses a nutritional composition for improving muscle functions and application. The nutritional composition for improving the muscle function, provided by the invention, is prepared from the following components in parts by mass: 40 to 60 parts of 1, 3-dioleic acid-2-palmitic acid triglyceride and 20 to 70 parts of 1-oleic acid-2-palmitic acid-3-linoleic acid triglyceride. A specific amount of OPO and OPL are compounded, and the two components have a synergistic effect, so that the exercise amount and the ATP content of an organism are remarkably increased, sarcopenia is relieved by improving energy metabolism, the muscle function is improved, and the food has a wide application prospect in the field of food and is worthy of popularization and application. The food can be used in health-care food, formula food for special medical purposes, infant formula food or special diet food.
Owner:JUNLEBAO DAIRY GRP CO LTD

Insulin secretion-promoting agent and blood sugar level improver using same, diabetes improver, and food

Provided is an insulin secretion-promoting agent comprising, as an active ingredient, a triglyceride represented by the following formula (I):wherein R1, R2 and R3 each denotes a saturated fatty acid residue, at least one of which is a pentadecanoic acid residue. An insulin secretion-promoting action of the pentadecanoic acid triglyceride at the time of elevated blood glucose level is discovered, and pharmaceuticals and health foods for improving blood glucose level and diabetes are provided using this triglyceride.
Owner:REFINE HLDG CO LTD +1

Repair composition based on mussel mucin and application of repair composition in skin barrier repair

The invention relates to the technical field of repair compositions, and discloses a repair composition based on mussel mucin and application of the repair composition in skin barrier repair. The invention discloses a mussel mucoprotein-zinc composite microcapsule repair agent, which is prepared from the following components in parts by weight: mussel mucoprotein-zinc composite microcapsules, modified carboxymethyl chitosan, isolactone palmitate, a pH response type ceramide slow release system, dimeticone, cetostearyl alcohol, a calcium ion activating agent, an auxiliary repair factor, beheneth-25, caprylic / capric triglyceride, glyceryl monostearate, glyceryl distearate, pentanediol and citric acid. The preparation method comprises the following steps: adding ethanol, phenoxyethanol / ethylhexylglycerin, trehalose, beta-glucan and purified water; according to the whole technical scheme, through functional complementation and process optimization of all the components, synergistic interaction is achieved, the transpedermis water loss amount can be rapidly reduced, the water content of the skin cuticle is increased, the damaged skin barrier structure can be repaired from the source, and the resistance and stability of the skin are remarkably improved.
Owner:HEFEI SHELL PARTY INNOVATIONS TECH CO LTD

Nutritional composition for promoting absorption of fatty acid and mineral substances and application

The invention belongs to the field of functional substance research, and particularly relates to a nutritional composition for promoting absorption of fatty acid and mineral substances and application. The nutritional composition provided by the invention comprises necessary active ingredients shown as the following (I) and (II): (I) 1, 3-dioleic acid-2-palmitic acid triglyceride; (II) a milk fat globule membrane, and / or, 2 '-fucosyllactose; moreover, in the nutritional composition, the mass ratio of the necessary active component shown in (I) to the necessary active component shown in (II) is (5-10): (0.5-10). The combination of OPO and MFGM and / or 2 '-FL provided by the invention can be beneficial to promoting the absorption of the body to fatty acids and mineral substances, and especially can be beneficial to promoting the transmembrane transport capability of intestinal cells of the body to fatty acids and mineral substances, so that the absorption efficiency is improved.
Owner:FEIHE (AR HORQIN BANNER) DAIRY CO LTD +1

Quick-acting red-removing repairing product and method thereof

The invention belongs to the technical field of skin care products, and discloses a quick-acting red-removing repair product which comprises the following components: water, caprylic / capric triglyceride, glycerol, sorbitol, phosphatidylcholine, 1, 3-propylene glycol, xanthan gum, eicosapentaenoic acid, docosahexaenoic acid, phytosphingosine, centella asiatica extract and tocopheryl acetate. A turmeric rhizome extract and 1, 2-hexanediol. Through mutual cooperation of the turmeric root extract and the centella asiatica extract, by taking enhancement of skin immune regulation and skin barrier functions as an action mechanism, on one hand, skin inflammatory response can be inhibited, and inflammation, microorganisms and bacteria can be effectively resisted, and on the other hand, skin barrier reconstruction can be promoted, wound healing can be promoted, and an ECM matrix can be protected; in addition, the eicosapentaenoic acid, the docosahexaenoic acid, the turmeric root extract, the phytosphingosine and the centella asiatica extract are wrapped by the nano-microcapsule liposome, so that the activity of the product can be ensured.
Owner:GUANGZHOU GRET BIOTECHNOLOGY CO LTD

Collagen production promoter, wrinkle improver, topical skin care composition, and beauty food or beverage

Provided is a collagen production promoter comprising, as an active ingredient, a triglyceride represented by the following formula (I), wherein R1, R2 and R3 each denotes a saturated fatty acid residue, at least one of which is a pentadecanoic acid residue. The triglyceride comprising the pentadecanoic acid promotes the production of skin fibroblasts and collagen, and can be used as a topical skin care composition and a beauty food or beverage for improving the condition of skin.
Owner:REFINE HLDG CO LTD

Skin moistening oil containing water-soluble active matters and preparation method of skin moistening oil

PendingCN121971321AmildImprove the pleasure of useCosmetic preparationsToilet preparationsPolymer scienceActive agent
The invention relates to the field of cosmetics, in particular to skin moistening oil containing a water-soluble active matter and a preparation method of the skin moistening oil. The skin moistening oil of the water-soluble active matter is prepared from the following raw materials in parts by mass: 0.1-1 part of a phase A, 3-15 parts of a phase B and 80-100 parts of a phase C, wherein the phase A is a water-soluble component, and the water-soluble component comprises one or more of deionized water, VC ethyl ether and nicotinamide; the phase B is a solvent, and the solvent comprises one or more of ethyoxyl diethylene glycol, 1, 2-pentanediol, isopentanediol and isostearic acid; the phase C is skin moistening oil, and the skin moistening oil comprises caprylic / capric triglyceride. The skin moistening oil product provided by the invention has the advantages of clear and transparent appearance, good fluidity, excellent stability, no need of adding a surfactant or a solubilizer, mildness, no irritation, simple process, controllable cost, good practical value and good application prospect.
Owner:SHANGHAI ZHONGYI DAILY CHEM CO LTD +1

Cosmetic oil with whitening, soothing and anti-aging effects and preparation method thereof

The invention discloses cosmetic oil with whitening, soothing and anti-aging effects and a preparation method of the cosmetic oil. The plant essential oil is prepared from the following raw materials in parts by weight: 0.5 to 1.5 parts of sunflower seed oil, 0.01 to 0.05 part of lupinus albus seed extract, 0.0001 to 0.001 part of tocopherol, 0.01 to 0.05 part of rosemary leaf extract, 0.001 to 0.1 part of dimethyl methoxy benzodihydropyranol, 50 to 90 parts of caprylic / capric triglyceride, 0.01 to 0.2 part of ascorbyl tetraisopalmitate, 0.01 to 0.2 part of bisabolol, 5 to 20 parts of squalane, 2 to 8 parts of simmondsia chinensis seed oil, 5 to 15 parts of meadowfoam seed oil and 0.1 to 1 part of lavender oil. And 0.3-1 part of a centella asiatica extract. According to the cosmetic oil product provided by the invention, by optimizing the use of substances, the composition has triple effects of whitening, relieving and resisting aging, can meet multiple skin care requirements of consumers at the same time, and is wide in market application range.
Owner:WUHAN MAYINGLONG MASSIVE HEALTH CO LTD

Traditional Chinese medicine composition for reducing uric acid level and preparation method thereof

The invention belongs to the field of preparation of medicaments for reducing uric acid, and particularly relates to a traditional Chinese medicine composition for reducing uric acid level and a preparation method thereof. Piperine, oat beta-glucan and medium chain triglyceride are mixed to react, a carrier material with a net structure is formed, a uric acid reducing solution obtained through adsorption and fermentation is freeze-dried, and the obtained efficient uric acid reducing component can remarkably and efficiently reduce the uric acid level in an organism; the regulating component is mixed with the metabolism promoting component obtained after powdering, the mixture is put into the coating material which can form a transparent film after being dried, and freeze spray drying is performed to obtain the long-acting agent which can stably play a role in a long-acting manner; the composition for maintaining stability and improving taste is uniformly sprayed on the surface of the traditional Chinese medicine component for reducing the uric acid level, and the prepared traditional Chinese medicine composition for reducing the uric acid level is remarkable and efficient in effect, improved in taste, free of peculiar smell, beneficial to persistent taking and free of irritation to liver and kidney after being taken for a long time.
Owner:SHANXI FUNCTIONAL FOOD RES INST OF SHANXI AGRI UNIV

Blumea oil gel as well as preparation method and application thereof

The invention provides blumea oil gel as well as a preparation method and application thereof, and relates to the technical field of daily chemicals. The blumea oil gel provided by the invention comprises the following components in percentage by mass: 45-65% of vegetable fat, 25-40% of polyol and 10-15% of an emulsifier, the vegetable fat comprises the following components in percentage by mass: 5-10% of folium artemisiae argyi essential oil, 30-40% of meadowfoam seed oil and 50-65% of caprylic / capric triglyceride. The meadowfoam seed oil and the caprylic / capric triglyceride are added into the vegetable fat component, so that volatilization of the folium artemisiae argyi essential oil can be reduced, and stabilization of effective components is facilitated; according to the blumea oil gel disclosed by the invention, the blumea oil gel is jointly formed by a proper amount of polyhydric alcohol, an emulsifier and vegetable fat containing the blumea oil, an oil gel system with a three-dimensional network structure can be formed, and a continuous oil phase in the system is fixed in a gel network, so that the stability of effective components is improved, and meanwhile, percutaneous absorption can be better promoted.
Owner:NANJING INST FOR THE COMPREHENSIVE UTILIZATION OF WILD PLANTS CHINA COOP +1

Quick-curing matte silicone sealant and preparation method thereof

The invention relates to the technical field of silicone rubber sealing materials, and discloses a fast-curing matte silicone sealant and a preparation method thereof.The silicone sealant is prepared from, by mass, 100 parts of alpha, omega-dihydroxy polydimethylsiloxane, 5-15 parts of a reactive plasticizer, 70-120 parts of calcium carbonate, 5-10 parts of a cross-linking agent, 1-5 parts of a coupling agent, 0.5 part of a catalyst and 0.5-1 part of a vulcanization accelerator; 0.2 to 1.5 parts of a reaction type matte agent solution; the reaction type matte agent solution is a mixture of hydroxylated eleostearic acid triglyceride and a cross-linking agent. The silicone sealant prepared by the invention has the advantages of smooth surface, excellent matte effect, weather aging resistance, thixotropy, rapid curing and the like, can be used as a sealing material for high-end buildings, and has a wide application prospect.
Owner:CHENGDU GUIBAO SCI & TECH +1

Ultra-high molecular weight polyethylene pipe super-lubrication extrusion auxiliary agent and preparation method thereof

ActiveCN121517920AEpoxyPolymer science
The invention belongs to the technical field of pipes, and particularly relates to an ultra-high molecular weight polyethylene pipe super-lubrication extrusion aid and a preparation method thereof. The extrusion aid consists of the following components in parts by mass: 5-11 parts of an internal lubricant, 4-10 parts of an external lubricant, 3-5 parts of a plasticizer, 12-25 parts of a filler and 0.5-2 parts of an antioxidant, the external lubricant is prepared by mixing organic silicon modified epoxy oleic acid triglyceride, erucic acid, zinc stearate and stearic acid according to the mass ratio of 100: (20-40): (10-25): (5-15). The ultra-lubricating extrusion aid for the ultra-high molecular weight polyethylene pipe prepared by the invention realizes stable extrusion of ultra-high molecular weight polyethylene under the conditions of low energy consumption, high yield and high quality.
Owner:WEIFANG JUPU NEW MATERIAL TECH CO LTD

Bath oil with stability and foamability and preparation method thereof

The invention discloses bath oil with stability and foamability and a preparation method thereof, and relates to the technical field of daily chemical products. The vegetable oil consists of peony seed oil, grape seed oil and sunflower seed oil in a mass ratio of 1: 2: 2. The bath oil is prepared from the following raw material components in parts by weight: 45 to 50 parts of vegetable oil, 18 to 22 parts of a surfactant, 16 to 18 parts of fatty alcohol-polyoxyethylene ether, 8 to 12 parts of caprylic / capric triglyceride, 1 to 3 parts of span 80, 0.1 to 0.5 part of an antioxidant, 1 to 3 parts of cocamidomethyl MEA and 0.1 to 2 parts of essence. On the basis of the compound vegetable oil, the optimal adaptive surfactant is screened out, then the compound antioxidant is introduced, and the bath oil which is long-acting, stable, high in foaming quality, clean, mild, nourishing and comfortable is effectively formed.
Owner:JIANGSU OUYALI DAILY COSMETIC

Prophylactic, Progression Inhibitor, Ameliorant for Visual Field Defect Disorders, Light-Induced Ocular Tissue Disorders and Related Disorders, and Food Product

Provided is a composition for visual field defect disorders, glaucoma, light-induced ocular tissue damage and related disorders, which can be used as a food or drug for long-term administration, prevention, symptom relief and improvement. A composition comprising a triglyceride represented by the formula (I):(wherein R1, R2, and R3 are each a saturated fatty acid residue, and at least one of them is a pentadecanoic acid residue) as an active ingredient.
Owner:REFINE HLDG CO LTD

Stable injectable cannabidiol formulations

An injectable cannabidiol formulation for non-IV parenteral administration comprising, consisting essentially of, or consisting of: (a) a solvent system consisting of (i) an effective amount of at least one triglyceride oil; and (ii) an effective amount of at least one C1-C3 alkyl ester of a C6-C22 fatty acid; and (b) an effective amount of cannabidiol; wherein the formulation is free of water and ethanol, has a viscosity less than about 35 cP, and is phase stable and chemically stable. The formulation can further comprise at least one additional pharmaceutically acceptable excipient. Kits containing the formulation are also described.
Owner:CARDIOL THERAPEUTICS INC

A method for preparing high-quality bio-based 1,9-nonanediol

This invention discloses a method for preparing high-quality bio-based 1,9-nonanediol, comprising the following steps: transesterification, precipitation, fatty acid methyl ester refining, ozone oxidation pyrolysis, solvent recovery, esterification, dimethyl azelaate refining, and hydrogenation to obtain high-quality bio-based 1,9-nonanediol. This invention achieves gradient and full-component utilization of vegetable oil raw materials: the oil-based portion of triglycerides is used to produce high-quality bio-based 1,9-nonanediol, while simultaneously producing byproducts such as methyl palmitate, methyl stearate, propionic acid, hexanoic acid, and nonanoic acid; the glycerol-based portion of triglycerides is used as a byproduct of glycerol production. This invention utilizes esterification to reconstruct the products of ozone oxidation pyrolysis, converting the high-boiling-point monomethyl azelaate into the low-boiling-point dimethyl azelaate, achieving efficient separation from saturated fatty acid methyl esters. The dimethyl azelaate, as a raw material, is then hydrogenated to obtain high-quality nonanediol, significantly reducing production costs.
Owner:ZHEJIANG UNIV OF TECH

Composition for improving obesity or cognitive function comprising hemp seed fermentate

PCT designated stageWO2025234537A1Nervous disorderMetabolism disorderBiotechnologyRos scavenging
The present invention relates to a food composition for improving obesity or cognitive function, comprising a hemp seed fermentate prepared using the Pediococcus acidilactici SRCM201591 strain. The fermentate was confirmed for radical scavenging ability, ROS scavenging ability, and AChE inhibitory ability, and found to have an antioxidant effect as a high content of polyphenol was measured. An anti-obesity effect was also confirmed through assays for triglyceride inhibition and C. elegans size reduction, and antioxidant and anti-obesity related gene regulation effects were identified following administration of the fermented extract. Accordingly, the fermentate can be advantageously used in the manufacture of food for improving obesity or cognitive function.
Owner:FUTURE F BIOTECH +1

Preparation and application of sour horse milk-derived lactobacillus plantarum, enterococcus faecalis and composite freeze-dried microbial inoculum with synergistic probiotic function

PendingCN121294270AAntibacterial agentsBacteriaBiotechnologyMare milk
According to the invention, the traditional fermented koumiss in Xinjiang is collected, two novel multifunctional probiotic strains, namely, the lactobacillus plantarum SR6 GDMCC NO.66817 strain and the enterococcus faecalis SM5 GDMCC NO.66816 strain with good compatibility are separated and screened out, and the two strains have the characteristics of reducing blood fat, reducing cholesterol, removing triglyceride, resisting oxidation and antagonizing pathogenic bacteria, and have the characteristics of good cholate and gastrointestinal tract tolerance, high survival rate and good safety. The growth characteristics and compatibility of the two strains are improved; the inhibition rate of cholesterol esterase and pancreatic lipase; the method comprises the following steps: evaluating the triglyceride removal rate, antioxidant activity, pathogenic bacterium resistance, artificially simulated gastrointestinal fluid tolerance, strain drug resistance and safety, compounding lactobacillus plantarum SR6 and enterococcus faecalis SM5 strains according to a ratio of 1: 1 to prepare a freeze-dried bacterial agent, and keeping good survival rate (pgt; 0.05) and functional characteristics, the strain can be used as a functional direct vat set starter and is directly applied to production of fermented dairy products, and the biological activity of food is improved.
Owner:YILI NALA DAIRY GRP CO LTD +1

A method for preparing nervonic acid monoglyceride

This invention relates to the field of oil and fat synthesis technology, specifically to a method for preparing nervonic acid monoglyceride. In this invention, nervonic acid and glycerol are used as raw materials, and an esterification reaction is carried out under microwave assistance to obtain a first mixture containing nervonic acid monoglyceride, nervonic acid diglyceride, nervonic acid triglyceride, unreacted nervonic acid and glycerol, and a catalyst. Glycerol and the catalyst are removed by ethyl acetate extraction to obtain a second mixture. Subsequently, taking advantage of the temperature-sensitive nature of nervonic acid monoglyceride in edible oils, it is separated and purified to obtain nervonic acid monoglyceride. The esterification reaction under microwave assistance not only avoids the corrosion and contamination problems caused by traditional acid catalysts, but also significantly shortens the esterification reaction time, improves synthesis efficiency, and effectively inhibits the isomerization of cis-nervonic acid during the reaction, ensuring the stability of the product configuration.
Owner:SHANDONG YUANLITAI MEDICAL TECH CO LTD

Detection of bladder cancer

ActiveCN113302495BDisease diagnosisDimerBiomarker panel
The present invention provides a method for detecting the presence of or risk of bladder cancer in a female patient, the method comprising the steps of: detecting the presence of a biomarker panel in a sample isolated from a female patient, the biomarker panel comprising IL-13 and IL-12p70 and one or more biomarkers selected from the group consisting of BTA, midkine, PAI-1 / tPA, 8OHdG, CEA, CK18, Fibrillin, Creatinine, CXCL16, Cystatin B, Cystatin C, d-dimer, EGF, FAS, HAD, IL-1a, IL-1b, IL-4, IL-6, IL-7, IL-8, MCP-1, Microalbumin, MMP9 NGAL, MMP9 TIMP1, NGAL, NSE, Progranulin, TUP, TGFB1, Thrombomodulin, sTNFR1, TPA, VEGF and Triglyceride, and / or the concentration of albumin / microalbumin / protein to creatinine in a sample isolated from a female patient, expressed as an albumin:creatinine ratio; and assessing the result and comparing it to a normal control, wherein an increase in the presence of the biomarkers compared to the normal control indicates the presence or risk of cancer in the patient from which the sample was isolated.
Owner:RANDOX LAB LTD

Confectionery product

The present invention relates to a confectionery product comprising 20% to 70% by weight of a sweetener; and 20% to 70% by weight of a plant-based fat phase; wherein the plant-based fat phase has from 1.0% to 10.0% by weight of total lauric acid (C12: 0) and myristic acid (C14: 0); and from 20.0% to 70.0% by weight of total palmitic acid (C16: 0) and stearic acid (C18: 0); the percentage of acid is an acid bound as an acyl group in the glyceride of the plant-based fat phase and based on the total weight of C8 to C24 fatty acids; total palmitic acid (C16: 0) and stearic acid (C18: 0) in the second position of the triglycerides, which accounts for at least 1.0% of the percentage of total palmitic acid (C16: 0) and stearic acid (C18: 0) in the triglycerides of the plant-based fat phase (Sn-2 total palmitic acid and stearic acid%); up to 10.0% by weight of a total CN32 triglyceride, CN34 triglyceride, CN36 triglyceride, CN38 triglyceride, and CN40 triglyceride; the plant-based fat phase is based on total triglycerides present in the plant-based fat phase. The invention also relates to a method for preparing said confectionery product.
Owner:BUNGE LODERS CROKLAAN BV +1

Compositions and methods for treating diabetes

Disclosed herein are compositions and methods for treating diabetes, wherein the compositions comprise a GLP-1 agonist. The disclosed compositions are also effective in reducing body weight and improving triglyceride and cholesterol levels. Disclosed herein are methods for treating type 2 diabetes mellitus in a subject, for reducing A1C in a subject, for reducing body mass in a subject, and for modulating a hypoglycemic hormone level in a subject.
Owner:PURVIVA CORP

Lipid-lowering traditional Chinese medicine composition, lipid-lowering traditional Chinese medicine extract and preparation method and application of lipid-lowering traditional Chinese medicine extract

The invention provides a lipid-lowering traditional Chinese medicine composition and extract as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The lipid-lowering traditional Chinese medicine composition is prepared from the following raw materials: rhizoma cyperi and radix gentianae. The invention further provides an extract of the lipid-lowering traditional Chinese medicine composition. The extract is obtained by mixing rhizoma cyperi and radix gentianae and then co-extracting. The composition or the extract can be used for preparing medicines for preventing and / or treating hyperlipemia, and can be used for improving lipid metabolism disorder of liver cells and reducing the content of triglyceride and total cholesterol in the liver cells.
Owner:KUNMING UNIV OF SCI & TECH