157 results about "Polysorbate" patented technology

The invention discloses a diluent for whole blood lateral immunochromatography detection as well as a preparation method and a detection method thereof, and belongs to the technical field of immunochromatography detection. The diluent solves the technical problems of unsmooth chromatography, background interference, poor stability of detection results and the like caused by red blood cells during direct detection of whole blood samples. The diluent comprises a buffer system, an osmotic pressure regulator glycine, a nonionic surfactant polysorbate, an erythrocyte aggregation inducer polyvinylpyrrolidone, a dynamic viscosity regulator trehalose, a blocking protein, a stabilizer combination L-methionine and L-histidine, and a composite formula of water. Red blood cells are effectively induced to gather and intercept on the sample pad through the synergistic effect of all the components, and meanwhile the stability of the chromatography process and the activity of the detection reagent are maintained. The diluent is mainly used for lateral immunochromatography quantitative detection of markers such as pro-enkephalin, C-reactive protein, cardiac troponin I or N-terminal pro-brain natriuretic peptide in a whole blood sample.

The invention provides a method for grafting Tibetan white bark pine on Chinese pine, belongs to the technical field of needle-leaved tree species grafting, and solves the technical problem that the survival rate is lower than 40% due to slow joint healing, high pathogen infection rate and environmental fluctuation. According to the technical scheme, the method is characterized by comprising the following steps: cutting 1.8-2.2 cm of a vertical notch reaching xylem at the part, which is 2.5-3.5 cm exposed out of the surface of a culture medium, of a rootstock rhizome part; cutting the scion base into a symmetrical double-sided wedge shape, and immersing the scion base into a sodium citrate buffer solution containing polyvinylpyrrolidone, methyl salicylate and calcium chloride; the two sides of the vertical notch are coated with adsorption glue; inserting a scion alignment cambium and fixing by using a grafting belt; an ethanol water solution containing salicylic acid, trehalose and polysorbate 80 is applied to the interface every 2-3 days; maintaining the day temperature to be 23-25 DEG C, the night temperature to be 16-18 DEG C and the humidity to be 90-95%; when the young sprouts grow to 2-3 cm, the rootstocks are girdled, and trunks are cut off after 7-10 days. The method is used for large-scale breeding of the Tibetan pinus bungeana grafted seedlings.

The invention provides a docetaxel-loaded platelet delivery system as well as a preparation method and application thereof, and relates to the technical field of medicines. According to the invention, the docetaxel-loaded platelet delivery system is obtained by loading the docetaxel with the platelets for the first time, so that the problem that in the prior art, the traditional docetaxel preparation (injection) needs to be solubilized by polysorbate 80, so that allergy is easily caused is avoided, the safety and biocompatibility of the docetaxel medicine are improved, and the docetaxel-loaded platelet delivery system is suitable for clinical application. And the docetaxel-loaded platelet delivery system has excellent stability and can be stored at normal temperature for a long time. The invention provides the preparation method of the docetaxel-loaded platelet delivery system, and the method is simple to operate, high in encapsulation efficiency and drug loading rate and suitable for popularization. The docetaxel-loaded platelet delivery system disclosed by the invention has an outstanding treatment effect on melanoma and has a good application prospect.

The invention relates to the field of medicinal emulsifiable paste, in particular to compound fluconazole emulsifiable paste and a preparation method thereof. The compound fluconazole emulsifiable paste is prepared from the following components in parts by weight: 0.6 to 5 parts of fluconazole, 0.2 to 2 parts of neomycin sulfate, 0.1 to 0.2 part of triamcinolone acetonide, 5 to 15 parts of stearic acid, 10 to 25 parts of white vaseline, 2 to 8 parts of glyceryl monostearate, 0.5 to 3 parts of medicinal dimeticone, 1 to 5 parts of polysorbate-80, 0.1 to 0.3 part of sorbic acid, 0.1 to 1 part of vitamin E, 0.01 to 0.1 part of EDTA (Ethylene Diamine Tetraacetic Acid) disodium, 5 to 15 parts of glycerol and the balance of purified water, wherein the total amount is 100 parts. According to the application, the antioxidant property of the cream is improved by adding the vitamin E and the EDTA disodium, the vitamin E is used for directly scavenging free radicals, the EDTA disodium is used for eliminating an oxidation catalyst, and the quality guarantee period of the cream can be remarkably prolonged and the drug effect can be maintained by combining the vitamin E and the EDTA disodium.

The application relates to the technical field of cough-relieving medicines, and discloses a high-efficiency cough-relieving loquat particle composition which is composed of the following components in parts by weight: loquat leaf extract 30-40 parts; white front extract 10-15 parts; platycodon grandiflorum extract 6-10 parts; white mulberry bark extract 18-25 parts; stemona sessiliflora extract 7-10 parts; menthol 0.1-0.5 part; polyethylene glycol 2-5 parts; mannitol 8-12 parts; ethyl cellulose 3-6 parts; hydroxypropyl methyl cellulose 1-3 parts; phosphatidylcholine 1-3 parts; polysorbate 80 1-3 parts; cross-linked sodium carboxymethyl cellulose 4-6 parts; and sucrose 40-60 parts. The double dispersion system combining the immediate-release component and the sustained-release component is adopted, the solubility and the initial release speed of the traditional Chinese medicine extract are remarkably improved through the addition of polyethylene glycol and mannitol, and the technical effect that the drug effect appearing time is remarkably shortened is achieved. Compared with the technical scheme relying on only a single release mode in the prior art, the deficiency that the drug effect is slow and the symptoms of the patient cannot be timely relieved is solved.

The application discloses a kind of bumetanide tablets, raw materials include bumetanide 1 according to mass ratio;Corn starch 81~85;Lactose 50~54;Agar 0.1~0.3;Povidone K304~6;Polysorbate 80, 0.1~0.2;Silicon dioxide 3~4.5;Talcum powder 2~3.3;Magnesium stearate 0.3~0.7.Its preparation method includes the following steps: pretreatment, premixing, granulation, wet granulation, drying, dry granulation, total mixing, tabletting and packaging.The application introduces the synergistic system of trace agar and polysorbate 80 in the prescription.Agar, as a natural hydrophilic colloid, can form a hydrophilic network structure during the granulation process, and synergistically act with polysorbate 80, greatly improving the wettability and dispersibility of the slurry to ultrafine bumetanide, preventing drug agglomeration, so that the drug can be more evenly distributed in the granules during the subsequent drying and tabletting process.

The invention discloses an oyster enzymolysis ultrafiltration extract nasal spray and a preparation method thereof, the nasal spray comprises the following components: 5-10 wt% of oyster extract, 0.1-0.3 wt% of preservative, 0.05-0.15 wt% of sodium chloride and 0.1-0.3 wt% of emulsifier, the pH value is 5.5-6.5, the content of the preservative is 0.1-0.3 wt%, the content of the sodium chloride is 0.05-0.15 wt%, the content of the emulsifier is 0.1-0.3 wt%, and the balance is water. The preservative is one of benzalkonium chloride, sorbic acid and potassium sorbate, and the emulsifier is polysorbate 80. Through definite raw material composition, a step-by-step process and quality control, the bioavailability of active components is improved, the flavor of the product is optimized, the effect of safely and efficiently improving sleep is achieved, the problems of low bioavailability, poor flavor and potential safety hazards of an existing sleep improving product are solved, the process repeatability is high, and the preparation method is suitable for industrial production. The long-term use of people with chronic insomnia is facilitated.

This application relates to the field of feed processing technology and discloses a highly absorbable feed composition for nursery pigs containing compound probiotics. The composition includes the following ingredients: a basal diet, a live bacteria compound powder composed of freeze-dried *Lactobacillus plantarum* powder and freeze-dried *Bacillus coagulans* powder, medium-chain triglycerides, a PIT-responsive compound emulsifier composed of polysorbate-80 and sorbitan monooleate, anhydrous trehalose, glycerol, a micron-sized confinement carrier, which is a porous carrier obtained by high-temperature expansion and vacuum degassing of perlite powder, and fumaric acid. This invention employs anhydrous trehalose and glycerol to construct a high-permeability system, combined with medium-chain triglycerides and a compound emulsifier to form an oil-phase encapsulation, achieving the technical effect of effectively blocking external moisture penetration and improving the heat resistance of the bacteria.

The present application belongs to the technical field of biological enzyme preservation, and particularly relates to a bromelain freeze-drying protective agent and a preparation method thereof. The composition comprises the following components: 30-50 parts of trehalose, 8-10 parts of pullulan, 3-10 parts of malt dextrin, 12-22 parts of mannitol, 1-4 parts of sorbitol, 4-12 parts of glycine, 0.05-0.2 parts of polysorbate-20, 1.5-4.5 parts of a buffer, 0.2-0.8 parts of N-acetylcysteine, 0.05-0.3 parts of oxidized glutathione, 0.8-2.5 parts of PEG and 0.05-0.3 parts of an antioxidant. The present application takes trehalose-pullulan polysaccharide as a main skeleton, inhibits ice crystal growth and reduces water activity; mannitol constructs a crystal phase support network, and polysorbate-20 stabilizes the interface; oxidized glutathione temporarily seals mercapto groups, and microencapsulated N-acetylcysteine realizes controllable reduction during redissolution; and a sodium phosphate buffer system maintains pH stability.

The present disclosure relates to formulations comprising a protein comprising an Fc region (e.g., an antibody) and a surfactant such as a polysorbate (e.g., Polysorbate 20), and methods of purifying such proteins that improve stability of the surfactant such as a polysorbate in such formulations.

The invention relates to a detection method, in particular to a method for detecting aldehyde impurities in polysorbate 20. According to the method, interference caused by the purity of 2, 4-dinitrophenylhydrazine is avoided, derivatization of a reference substance is performed by adopting a method synchronously operating with a test sample, eight aldehyde ketone substances can be detected at the same time, and compared with literature methods, the method is high in specificity, good in precision, high in accuracy, simple and easy to implement and high in operability.

This invention belongs to the field of cosmetic technology and discloses a composition containing polypeptides, its preparation method, and its application. The composition provided by this invention comprises: polypeptides and a solubilizing and penetration-enhancing complex; the polypeptides include at least one selected from Codonopsis pilosula cyclic peptide B, conopeptide, carnosine, acetyl tetrapeptide-5, acetyl hexapeptide-8, and nonapeptide-1; the solubilizing and penetration-enhancing complex comprises the fermentation product filtrate of Kluyveromyces lactis / Ganoderma lucidum fruiting body extract, polyols, polysorbate, and ferulic acid. The composition provided by this invention, through the synergistic effect between its components, can effectively improve the solubility and stability of the polypeptides, preventing precipitation or exudation, while effectively promoting the transdermal absorption of the polypeptides; the composition provided by this invention has excellent antioxidant and anti-aging effects.

The present invention relates to a solution pharmaceutical preparation of cabazitaxel which is an ethanol-free direct infusion dilution of cabazitaxel and has excellent storage stability. Specifically, the present invention relates to a solution pharmaceutical preparation containing cabazitaxel as an active ingredient that contains a glycol solvent selected from polysorbate, polyethylene glycol, and / or propylene glycol and an organic acid. The pH of the solution pharmaceutical preparation diluted by water to a cabazitaxel concentration of 0.1 mg / mL is from higher than 3.5 to 5.5.

A pharmaceutical composition comprises a buffer-less aqueous formulation of adalimumab, a salt, a polyol, and a polysorbate. The formulation is suitable for injection.

The present application relates to the technical field of pharmaceutical preparation, and provides a calcium carbonate tablet, which comprises the following raw materials in parts by weight: 700-800 parts of calcium carbonate, 80-100 parts of corn starch, 15-25 parts of low-substitution hydroxypropyl cellulose, 1.5-2.5 parts of polysorbate-80, 7-9 parts of protein sugar, 3-5 parts of hypromellose, 2.5-3.0 parts of magnesium stearate and 15-25 parts of sodium carboxymethyl starch; wherein the calcium carbonate is selected from calcium carbonate with a particle size of 40-80 μm; the low-substitution hydroxypropyl cellulose and the sodium carboxymethyl starch are disintegrants, and the ratio of the amount of the low-substitution hydroxypropyl cellulose to that of the sodium carboxymethyl starch is 1:1. The present application also provides a preparation method of the calcium carbonate tablet. The calcium carbonate tablet has the advantages of short disintegration time, high dissolution rate, good bioavailability and good stability.

The application belongs to the technical field of biological medicine, and particularly relates to a freeze-dried preparation based on synergistic effect of trehalose and arginine for optimizing the performance of omalizumab reconstitution and a preparation method thereof. The preparation method comprises the following steps: preparing a histidine-hydrochloric acid buffer, dissolving omalizumab, trehalose, arginine and polysorbate 20 in the histidine-hydrochloric acid buffer to prepare a solution preparation; and freeze-drying the solution preparation to obtain the freeze-dried preparation; wherein the molar concentration ratio of trehalose to arginine in the solution preparation is 10-90:15-55. The freeze-dried preparation obtained by using the preparation method has a fast reconstitution speed and a fast bubble disappearance speed during reconstitution, can save time, meets the clinical emergency drug demand, and is more convenient to use.

A composition comprising an oily medium system and an active ingredient, and a method of increasing the bioavailable rate of an active ingredient, where the method comprises incorporating the active ingredient into an oily medium system, and where the oily medium system contains a vegetable oil and / or a component of a vegetable oil, the liquid does not contain the following substances: a phosphate buffer solution, polyethylene glycol, dimethyl sulfoxide, ethanol, polypropylene glycol, polysorbate, ethyl acetate, 12-hydroxystearic acid hydroxyethyl ester and tocopherol polyethylene glycol succinate; the active ingredient is selected from the group consisting of compounds of formula (I) wherein T1 is a C6 cyclic hydrocarbon and R1 is a C1-C8 aliphatic hydrocarbon group, pharmaceutically acceptable salts thereof, and combinations thereof.

The invention belongs to the field of papermaking, and particularly relates to an ink composition for food paper, which comprises resin, a first flavor agent, a second flavor agent, a first emulsifier, a second emulsifier and an organic solvent, the first flavor agent comprises a sweetening agent and a salty agent; the second flavor agent comprises an acidulant; the first emulsifier is selected from one or more of polyglycerol monooleate and sorbitan fatty acid; the second emulsifier is selected from one or more of polysorbate and triglycerol fatty acid ester; the mass content of the first emulsifier in the ink composition is 2%-6%; and the mass content of the second emulsifier in the ink composition is 2-6%. The invention also relates to a preparation method of the ink composition for the food paper, the food paper and a printing method thereof, and application of the ink composition. The ink composition disclosed by the invention is high in stability and has the flavor of coordinating and fusing sweet taste, salty taste and sour taste, and the flavor is continuously kept and is not easy to attenuate.

The invention belongs to the technical field of traditional Chinese medicine navel patches, and particularly relates to a composite medicine carrying navel therapy patch based on a PU film and a preparation method thereof.The composite medicine carrying navel therapy patch comprises an anti-sticking release film, a medicine carrying layer, a medical pressure-sensitive adhesive layer and a PU waterproof protective layer; the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 10 to 20 parts of rhizoma zingiberis, 10 to 15 parts of roasted rhizoma atractylodis macrocephalae, 8 to 12 parts of radix codonopsis, 5 to 10 parts of fructus evodiae, 5 to 10 parts of fructus foeniculi, 3 to 8 parts of cortex cinnamomi, 1 to 3 parts of borneol, 8 to 20 parts of polysorbate 80, 0.5 to 2 parts of carbomer 940, 1 to 3 parts of triethanolamine and 0.1 to 0.5 part of EDTA-2Na. By means of the integrated design of slow-release hydrogel drug loading and the multi-layer patch, efficient transdermal absorption and stable release of drugs are achieved, and the bioavailability and application comfort of the composite drug-loading navel therapy patch are improved.

The invention discloses a sweet-scented osmanthus and calendula child face cream for relieving allergy, moistening and repairing skin barrier and a preparation method thereof, and relates to the technical field of cosmetics. Osmanthus flower extract, calendula flower extract, coleus forskohlii root extract, radish seed extract, radix gentianae extract, centella asiatica extract, butyrospermum parkii butter and sunflower seed oil which are plant-sourced are utilized; a rahnella / soybean protein fermentation product, sodium hyaluronate, allantoin, mannitol, arginine, microcrystalline cellulose, polysorbate-60, phenoxyethanol and water are supplemented, so that a layer of protective film can be formed on the surface of the skin. The sweet-scented osmanthus and calendula cream for children is prepared according to the skin characteristics of children, is safe and non-toxic, and can be safely used at ease.

The invention discloses a zingiberenone A-containing composition with repairing and anti-wrinkle effects and a preparation process of the zingiberenone A-containing composition. The composition is prepared from the following components in percentage by weight: 0.0015 percent to 2 percent of zingiberenone A, 30 percent to 40 percent of glycerol, 30 percent to 40 percent of propylene glycol, 10 percent to 20 percent of polysorbate-80 and 10 percent to 20 percent of PEG-60 hydrogenated castor oil. The preparation process comprises the following steps: mixing the components, heating in a water bath at 40-50 DEG C, and ultrasonically stirring until the components are completely dissolved. Through specific auxiliary material compounding and process, the technical bottleneck of poor water solubility of zingiberenone A is overcome, so that zingiberenone A can be stably applied to cosmetics. Human body efficacy evaluation proves that the composition containing 0.0015% of zingiberenone A has remarkable anti-wrinkle, firming, moisturizing and soothing effects; the composition containing 0.015% of the composition has significant skin barrier repairing, moisturizing and soothing effects, and is mild and non-irritant. According to the invention, stabilization and efficacy verification of zingiberenone A in cosmetics are realized for the first time.

The invention discloses a method for extracting fine iron powder from iron-containing minerals by magnetic separation in the field of mineral processing, which comprises the following steps: firstly, coarsely crushing low-grade iron-containing raw ores, carrying out wet ball milling to obtain ore pulp, adding sodium hexametaphosphate and polysorbate 80, and stirring and dispersing; adjusting the pH value of the ore pulp to 5-6 by using diluted hydrochloric acid or sodium hydroxide, adding a quaternary composite modified material with a specific structure, and stirring to enable the material to be in full contact with the iron minerals; then the ore pulp is pumped into a high-gradient magnetic separator, and rough concentrate enriched with iron minerals is separated out under the specific gradient magnetic field intensity; and finally, stirring and desorbing at a constant temperature through a citric acid buffer solution at a certain temperature, magnetically separating to obtain high-grade fine iron powder, and washing and drying the desorbed modified material to be repeatedly used. According to the method, efficient selective extraction of iron in the low-grade iron-containing minerals is achieved through multi-stage structural design and process parameter optimization of the materials, the grade and the recovery rate of the fine iron powder are remarkably improved, and the modified materials can be recycled and are high in environmental friendliness.

The present invention generally pertains to methods of quantifying free fatty acids in a pharmaceutical formulation. In particular, the present invention pertains to a method of quantifying free fatty acids released from polysorbate hydrolysis in a pharmaceutical formulation comprising a pharmaceutical product, polysorbate and free fatty acids, using liquid chromatography-mass spectrometry, without the use of an extraction step.

The invention discloses low-viscosity essence lotion with a liquid crystal structure and a preparation method of the low-viscosity essence lotion. The low-viscosity essence emulsion with the liquid crystal structure comprises the following components in percentage by mass: 1.2%-8.5% of an emulsifier capable of forming the liquid crystal structure, 3%-20% of an emulsifying synergistic composition, 1%-5% of an oil phase component, 64.5%-94.8% of a water phase component, 0%-1% of a pH value regulator and 0%-1% of an antioxidant, the emulsifier capable of forming a liquid crystal structure comprises any one or more of hydrogenated lecithin, polysorbate-20 and polyglycerol-3 polydimethylsilyl hydroxyethyl polydimethylsiloxane, and the content of the hydrogenated lecithin is 0.7%-5%. The low-viscosity essence lotion with the liquid crystal structure provided by the invention is refreshing, easy to absorb and excellent in moisturizing effect.

A cyclocurcumin-based composition consisting of: a cyclocurcumin component present at 20 to 40 wt% of the total composition; a curcuminoid component present at 30 to 50 wt%, comprising 20 to 30 wt% curcumin, 5 to 10 wt% demethoxycurcumin, and 3 to 8 wt% bisdemethoxycurcumin; a solubilizer component present at 5 to 15 wt%, comprising polysorbate at 3 to 8 wt% and lecithin at 3 to 7 wt%; a complexing component present at 5 to 12 wt%, comprising cyclodextrin inclusion complexes; and a nanoparticulate component present at 3 to 10 wt%, comprising cyclocurcumin particles with a particle size in the range of 50 nm to 200 nm. consists of a polymer stabilizing component, which is present in an amount of 4 to 10 wt.-% is present and comprises polyvinylpyrrolidone or polyethylene glycol, a phospholipid complex component present in an amount of 3 to 8 wt% and consisting of phosphatidylcholine complexes, and an encapsulation component present in an amount of 2 to 6 wt% and containing maltodextrin or gum arabic, the composition being configured to ensure improved solubility, stability and bioavailability.

The present invention relates to insulin formulations comprising polysorbate 80. The present invention provides, inter alia, aqueous liquid pharmaceutical formulations comprising insulin or an insulin analogue, ionic zinc, a chelating agent, and polysorbate 80.

The embodiment of the invention provides anti-hair-loss, plump and dense hair essence, and relates to the field of hair care essence. The essence is prepared from water, ethyl alcohol, butanediol, PPG-26-butanol polyether-26, PEG-40 hydrogenated castor oil, tetrahydromethylpyrimidine carboxylic acid, 1, 2-hexanediol, caprylyl glycol, a ginseng root extract, palmitoyl tetrapeptide-7, a cacumen biotae extract, 1, 2-hexanediol, 1, 3-pentanediol, 1, 3-pentanediol, 1, 3-pentanediol, 1, 3-pentanediol, 1, 3-pentanediol and the like. The preparation method comprises the following steps: adding 1, 3-propylene glycol, phenoxyethanol, p-hydroxyacetophenone, carbomer, triethanolamine, adenosine, hydrolyzed sodium hyaluronate, hydrolyzed collagen, hydrolyzed elastin, caramel color, a scutellaria baicalensis root extract, a ginger root extract, copper tripeptide-1, a chamomilla recutita flower extract, glycerin, polysorbate-20, lactic acid, ethylhexylglycerin, carnosine, acetyl hexapeptide-8, palmitoyl pentapeptide-4, 2, 4-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1 The composition is prepared from the following raw materials: palmitoyl tripeptide-1, rosemary leaf extract, acetyl hexapeptide-8, arginine / lysine polypeptide, acetyl tetrapeptide-2 and acetyl tetrapeptide-5.

The invention belongs to the field of pharmaceutical preparations, and particularly relates to a pharmaceutical composition containing chlorbuconazole and a preparation method of the pharmaceutical composition. The invention provides a pharmaceutical composition containing chlorbuconazole as well as a preparation method and application of the pharmaceutical composition. Specifically, the invention discloses a pharmaceutical composition, the pharmaceutical composition comprises chlorbuconazole or a pharmaceutically acceptable salt thereof, polyethylene glycol 400, sorbitan oleate and polysorbate 80, the chlorbuconazole or the pharmaceutically acceptable salt thereof accounts for 1-10% of the total weight of the pharmaceutical composition, and the moisture content of the pharmaceutical composition is lower than 10%. The pharmaceutical composition disclosed by the invention has good dissolution rate and relatively high stability.

The invention provides an antibacterial dressing composition and a medical gynecological protection pad, and belongs to the technical field of medical dressings. The composition is prepared from 70 to 90 parts of water, 8 to 10 parts of polyethylene glycol, 4 to 6 parts of glycerol, 0.3 to 0.7 part of carbomer, 0.06 to 0.15 part of L-cysteine, 4 to 8 parts of chitosan quaternary ammonium salt, 0.3 to 0.8 part of panthenol, 0.4 to 0.7 part of tocopheryl acetate, 0.2 to 0.4 part of sodium hyaluronate, 0.1 to 0.3 part of chlorhexidine digluconate, 3 to 4 parts of polyvinylpyrrolidone, 1 to 5 parts of sodium alginate, 0.1 to 0.3 part of polysorbate, 0.6 to 0.9 part of luteoloside, 0.1 to 0.2 part of quercetin and 0.05 to 0.2 part of sophocarpidine. Chitosan quaternary ammonium salt and chlorhexidine digluconate are used as bactericidal components, quercetin and sophocarpidine are added to serve as bacteriostatic agents, and the bactericidal components, active components such as panthenol, tocopheryl acetate and galuteolin and a film-forming agent form a dispersion system. The antibacterial facial mask has remarkable antibacterial property, and has the effects of resisting inflammation, preserving moisture, promoting tissue repair and the like. The gynecological protection pad acts on the surface of vulva inflammation, and the exact treatment effect can be achieved.

The application discloses a method for detecting the dissolution curve of ezetimibe and rosuvastatin calcium tablets, and belongs to the technical field of drug detection. The method uses an aqueous solution containing 0.1-0.3 wt% polysorbate 80 as a dissolution medium, and performs dissolution according to a dissolution instrument basket method, wherein the rotating speed of the rotating basket is 50-100 revolutions per minute, and the mesh number of the rotating basket is 10 meshes. The method provided by the application has good dissolution for both ezetimibe and rosuvastatin calcium, and has the characteristics of strong specificity, high sensitivity, high accuracy, good durability and the like, can effectively distinguish the difference between self-prepared preparations and reference preparations, and is more universal and practical, and is more simple and efficient in operation.