322 results about "Polysorbate" patented technology

The invention discloses a scalp essence capable of controlling oil and removing dandruff and a preparation method thereof, and provides the scalp essence capable of controlling oil and removing dandruff. The formula consists of the following raw materials: water, saccharomycetes / rice fermentation product filtrate, butanediol, phenoxyethanol, caprylic acid / capric triglyceride, galactose yeast-like bacterium fermentation product filtrate, allantoin, a saccharomycetes / zinc fermentation product, nicotinamide, arginine, polysorbate-20, hydrogenated lecithin, acrylic acid (ester) / C10-30 and an alkanol acrylate cross-linked polymer. Hydrolyzed sodium hyaluronate and trace components. According to the oil-controlling and dandruff-removing scalp essence disclosed by the invention, through the synergistic interaction among the raw materials, the effects of replenishing water, preserving moisture, controlling oil and removing dandruff are increased, the effects of relieving, recovering oil-water balance, recovering skin elasticity and delaying senescence are also achieved, the effects of preventing hair loss and nourishing hair are also achieved, and meanwhile, the oil-controlling and dandruff-removing scalp essence has the advantage of being stable in storage.

The invention provides a culture method for improving immunity of fishes. The culture method comprises the following steps: S1, selection of culture points; S2, specification and layout of net cages; S3, selection and throwing of fish fries; according to the fry disinfection method disclosed by the invention, the fry are soaked and disinfected by using a compound disinfectant prepared from povidone iodine, polysorbate, citric acid and vitamin C in a specific proportion, so that pathogenic microorganisms on the surfaces and gill parts of fish bodies are effectively killed. According to the breeding management, the immunity of the fish body is comprehensively enhanced by feeding the fish with an immune conditioner composed of campesterol palmitate, immunomodulatory peptide, beta-glucan and astaxanthin in a specific proportion. According to the bottom mud management, the content of harmful substances is reduced by putting a bottom mud modifier composed of sodium molybdate, nitrifying bacteria, photosynthetic bacteria, tetrandrine and sodium alginate in a specific proportion, growth of pathogenic bacteria is inhibited, nutrient substance circulation is promoted, the water quality environment is optimized, and healthy growth of fry is promoted.

The invention discloses a diluent for whole blood lateral immunochromatography detection as well as a preparation method and a detection method thereof, and belongs to the technical field of immunochromatography detection. The diluent solves the technical problems of unsmooth chromatography, background interference, poor stability of detection results and the like caused by red blood cells during direct detection of whole blood samples. The diluent comprises a buffer system, an osmotic pressure regulator glycine, a nonionic surfactant polysorbate, an erythrocyte aggregation inducer polyvinylpyrrolidone, a dynamic viscosity regulator trehalose, a blocking protein, a stabilizer combination L-methionine and L-histidine, and a composite formula of water. Red blood cells are effectively induced to gather and intercept on the sample pad through the synergistic effect of all the components, and meanwhile the stability of the chromatography process and the activity of the detection reagent are maintained. The diluent is mainly used for lateral immunochromatography quantitative detection of markers such as pro-enkephalin, C-reactive protein, cardiac troponin I or N-terminal pro-brain natriuretic peptide in a whole blood sample.

The invention relates to the technical field of cosmetics, and particularly discloses an oil-control moisturizing pressed powder with a multi-layer microporous structure and a preparation method of the oil-control moisturizing pressed powder. The oil-control moisturizing pressed powder with the multi-layer microporous structure is characterized by comprising powder, a first emulsion and a second emulsion, the first emulsion is prepared by mixing a first humectant, hydrogenated lecithin, C12-20 acid PEG-8 ester, polysorbate-80 and water; the second emulsion is formed by mixing a second humectant and water; the preparation method comprises the following steps: mixing and drying the powder and the first emulsion, and then mixing with the second emulsion to obtain slurry; and freeze-drying the slurry at-80 to-60 DEG C, then freeze-drying at-40 to-5 DEG C, and finally freeze-drying at-5 to 45 DEG C to obtain the pressed powder. A uniform three-dimensional micropore structure is formed in the oil-controlling and moisturizing pressed powder, more moisturizing components can be loaded, the contact area with the skin is increased, and therefore the oil-controlling and moisturizing pressed powder has excellent moisturizing performance and skin feeling.

The invention provides a method for grafting Tibetan white bark pine on Chinese pine, belongs to the technical field of needle-leaved tree species grafting, and solves the technical problem that the survival rate is lower than 40% due to slow joint healing, high pathogen infection rate and environmental fluctuation. According to the technical scheme, the method is characterized by comprising the following steps: cutting 1.8-2.2 cm of a vertical notch reaching xylem at the part, which is 2.5-3.5 cm exposed out of the surface of a culture medium, of a rootstock rhizome part; cutting the scion base into a symmetrical double-sided wedge shape, and immersing the scion base into a sodium citrate buffer solution containing polyvinylpyrrolidone, methyl salicylate and calcium chloride; the two sides of the vertical notch are coated with adsorption glue; inserting a scion alignment cambium and fixing by using a grafting belt; an ethanol water solution containing salicylic acid, trehalose and polysorbate 80 is applied to the interface every 2-3 days; maintaining the day temperature to be 23-25 DEG C, the night temperature to be 16-18 DEG C and the humidity to be 90-95%; when the young sprouts grow to 2-3 cm, the rootstocks are girdled, and trunks are cut off after 7-10 days. The method is used for large-scale breeding of the Tibetan pinus bungeana grafted seedlings.

The invention provides an anti-freezing denaturation agent for golden and tiger hybrid spotted fish meat protein and a preparation method of the anti-freezing denaturation agent. The invention relates to an anti-freezing denaturation agent for protein of Jinhu hybrid spotted fish. The anti-freezing denaturation agent is prepared from the following raw materials in parts by weight: 5 to 8 parts of trehalose-mannitol, 0.5 to 1 part of nano chitosan, 0.2 to 0.5 part of rosmarinic acid and 0.1 to 0.2 part of polysorbate-80. The trehalose-mannitol is prepared from trehalose and mannitol. Aiming at the characteristics of Jinhu hybrid spotted fish meat, trehalose-mannitol, nano chitosan, rosmarinic acid and polysorbate-80 are taken as raw materials and compounded to obtain a new formula of the protein anti-freezing denaturation agent for the Jinhu hybrid spotted fish meat, and the anti-freezing denaturation agent prepared by adopting the formula and the process disclosed by the invention can be used for inhibiting protein degradation and improving the anti-freezing denaturation effect of the Jinhu hybrid spotted fish meat. The decrease range of MP protein concentration, MP total sulfydryl content and MP Ca < 2 + >-ATPase activity of the antifreeze agent is obviously reduced, and the effect of the antifreeze agent is superior to that of a commercially available antifreeze agent. Moreover, the anti-freezing denaturation agent for the protein of the Jinhu hybrid spotted fish does not contain phosphorus, and has the advantages of safety and high efficiency.

The invention relates to the technical field of cosmetics, in particular to preparation and application of a cyclodextrin-coated azelaic acid oil-control skin-care product. Comprising the following steps: S1, adding deionized water into a mixer, adding a cyclodextrin-azelaic acid inclusion compound, nicotinamide and allantoin, mixing to obtain a water phase, mixing glycerol, caprylic / capric triglyceride, polydimethylsiloxane, polysorbate-80 and tocopheryl acetate to obtain an oil phase, slowly adding the oil phase into the water phase, and shearing and emulsifying to obtain a nanoemulsion; and S2, cooling the nano-emulsion, adding carbomer while stirring, continuously cooling to room temperature, sequentially adding phenoxyethanol, ferulic acid, menthol and essence, adjusting the pH value of the emulsion with triethanolamine, homogenizing, defoaming, disinfecting and filling. By adjusting the proportion of the components in the formula, the skin feeling of the product can be further optimized, so that the product is more comfortable and not greasy, and a lasting oil control effect is provided.

The invention discloses thermal insulation and waterproof integrated phase change heat storage mortar and a preparation method thereof, and belongs to the technical field of building materials. The mortar is prepared from the following raw materials: cement, water, fine aggregate, shape-stabilized phase-change material super-hydrophobic silicon dioxide, a water reducing agent and polysorbate, the preparation method of the shape-stabilized phase change material-coated super-hydrophobic silicon dioxide comprises the following steps: S1, carrying out hydrophobic modification on diatomite to obtain hydrophobic modified diatomite; s2, adding n-hexadecane into the hydrophobic modified diatomite, and obtaining a shape-stabilized phase change material through a vacuum impregnation method; and S3, adding the shape-stabilized phase change material and the super-hydrophobic silicon dioxide into water, stirring, performing ultrasonic dispersion, and filtering and drying to obtain the shape-stabilized phase change material-coated super-hydrophobic silicon dioxide. The shape-stabilized phase-change material and super-hydrophobic silicon dioxide are doped into the mortar, so that the compressive strength, the thermal insulation performance and the waterproof performance of the mortar are remarkably improved, and the mortar has excellent durability.

The invention relates to a string maintenance nanoemulsion and a preparation method thereof, and belongs to the technical field of string maintenance. The nanoemulsion comprises polysorbate 80 and sorbitan stearate 60 as main emulsifiers, glyceryl monostearate, cetyl alcohol and stearyl alcohol as auxiliary emulsifiers, liquid paraffin and xanthan gum for adjusting the consistency, chitosan-loaded sodium hyaluronate nanoparticles as a long-acting humectant, and glycerol and propylene glycol as humectants and also can be used as anti-freezing agents. Ethylparaben is used as a preservative; and essence and the balance of water can be selectively added. Uniformly mixing and stirring the water-soluble components; uniformly mixing and stirring oil soluble components; and adding the oil phase into the water phase, stirring to form primary emulsion, emulsifying, homogenizing, cooling, and adding essence to obtain the product. According to the invention, the chitosan-loaded sodium hyaluronate nanoparticles are introduced to realize long-acting moisturizing and moistening of strings, and have the advantages of fine and soft texture and the like.

The invention relates to the field of corrugated paper preparation, in particular to moisture-proof and mildew-proof corrugated paper and a preparation method thereof. The composite board comprises a board core located in the center and paper layers located on the two sides of the board core. A moisture-proof and mildew-proof bonding layer is arranged between the board core and the paper layer; a moisture-proof and mildew-proof protective layer is arranged on the outer side of the The moisture-proof and mildew-proof bonding layer is obtained by coating a bonding agent; the adhesive comprises activated carbon powder, kaolin, water, hydrogen peroxide, potassium permanganate, starch, caustic soda, borax, a defoaming agent and a special drying catalyst; the moisture-proof and mildew-proof protective layer is obtained by coating a protective agent; the protective agent is prepared from activated carbon powder, kaolin, paraffin, dimethyl silicone oil, absolute ethyl alcohol, tetrabutyl titanate, an emulsifier OP-10, polysorbate-80, an acetic acid solution, styrene-acrylic emulsion, a film-forming agent, a dispersing agent and a preservative. On the basis of the original performance, multi-layer moisture-proof and mildew-proof effects are further achieved, the quality of the corrugated paper is improved, objects contained in the corrugated paper are protected, the strength of the corrugated paper is enhanced, and the service life of a carton is prolonged.

The invention relates to a production method of a high-end filter aluminum foil for a coating, which comprises the following steps: (1) stirring and mixing polymethylene polyphenyl isocyanate, polyol, a polymerization inhibitor, a catalyst and water, and reacting to obtain a prepolymer; (2) mixing the prepolymer with polysorbate and cyclopentane to obtain a base coating; (3) the surface of the aluminum foil is coated with the base layer paint, and the aluminum foil coated with a base layer coating is obtained; (4) adding a surfactant into water, uniformly mixing, adding silicate, a boron compound and nano silicon dioxide, and uniformly stirring to obtain a hydrophilic coating; and (5) the surface of the base layer coating is coated with hydrophilic paint, and the coating aluminum foil is obtained. The base layer coating is of a porous structure, the roughness of the surface of the aluminum foil is improved, the hydrophilicity of the hydrophilic coating is improved to a certain extent through the roughness of the porous structure in the base layer coating, and the hydrophilic angle of the hydrophilic coating is reduced.

The invention discloses an agricultural synergist containing astragalus polysaccharide and application of the agricultural synergist, and belongs to the technical field of killing agents for biopesticides. The synergist comprises astragalus polysaccharide, a polysorbate / lecithin compound emulsifier, a carboxymethyl chitosan / siloxane penetrant and a modified accelerant synthesized by palladium catalysis. Polysaccharide is structurally modified through a blue light LED induced tetra (triphenylphosphine) palladium catalytic reaction, and the epidermal penetration efficiency of the biopesticide on tetranychus urticae is improved by 3.2 times in combination with the synergistic permeation effect of a siloxane derivative. The mite killing rate of the suspending agent prepared according to a preferable formula reaches 92.5% within 24 hours, and the lasting period is prolonged to 14 days. The system overcomes the defects of slow effectiveness and poor stability of the traditional biopesticide, by means of a targeted combination mechanism of natural components, the environment friendliness is kept while the original pesticide dosage is reduced by 50%, and the system is particularly suitable for the pest control requirement of organic agriculture.

The invention discloses a special-effect foliar fertilizer for improving cold resistance of durian seedlings as well as a preparation method and application of the special-effect foliar fertilizer, and belongs to the technical field of durian planting. The special-effect foliar fertilizer prepared by the invention is prepared from the following raw materials in parts by weight: 2 to 5 parts of fulvic acid, 10 to 20 parts of antifreeze agent, 0.5 to 2 parts of pine needle extract, 3 to 8 parts of alginate oligosaccharide, 0.3 to 0.8 part of 14-hydroxybrassinosterol, 0.2 to 0.5 part of 0.01 to 0.1 percent v / v polysorbate-20, 2 to 4 parts of chitosan, 1 to 3 parts of trehalose, 0.1 to 1 part of brassinolide, 0.1 to 0.3 part of salicylic acid and 6 to 10 parts of glycerol. The special-effect foliar fertilizer is simple to prepare, safe overwintering of durian seedlings at the low temperature of 4-15 DEG C can be effectively guaranteed, and the problems of dead seedlings and runt seedlings caused by low temperature are remarkably solved. The durian seedling culture medium is safe and environment-friendly in components, is beneficial to reduction of environmental pollution and pesticide residues, provides rich nutrition for breeding and growth of durian seedlings, and has remarkable application potential for promoting development of the durian industry.

The invention provides a docetaxel-loaded platelet delivery system as well as a preparation method and application thereof, and relates to the technical field of medicines. According to the invention, the docetaxel-loaded platelet delivery system is obtained by loading the docetaxel with the platelets for the first time, so that the problem that in the prior art, the traditional docetaxel preparation (injection) needs to be solubilized by polysorbate 80, so that allergy is easily caused is avoided, the safety and biocompatibility of the docetaxel medicine are improved, and the docetaxel-loaded platelet delivery system is suitable for clinical application. And the docetaxel-loaded platelet delivery system has excellent stability and can be stored at normal temperature for a long time. The invention provides the preparation method of the docetaxel-loaded platelet delivery system, and the method is simple to operate, high in encapsulation efficiency and drug loading rate and suitable for popularization. The docetaxel-loaded platelet delivery system disclosed by the invention has an outstanding treatment effect on melanoma and has a good application prospect.

The invention relates to the field of medicinal emulsifiable paste, in particular to compound fluconazole emulsifiable paste and a preparation method thereof. The compound fluconazole emulsifiable paste is prepared from the following components in parts by weight: 0.6 to 5 parts of fluconazole, 0.2 to 2 parts of neomycin sulfate, 0.1 to 0.2 part of triamcinolone acetonide, 5 to 15 parts of stearic acid, 10 to 25 parts of white vaseline, 2 to 8 parts of glyceryl monostearate, 0.5 to 3 parts of medicinal dimeticone, 1 to 5 parts of polysorbate-80, 0.1 to 0.3 part of sorbic acid, 0.1 to 1 part of vitamin E, 0.01 to 0.1 part of EDTA (Ethylene Diamine Tetraacetic Acid) disodium, 5 to 15 parts of glycerol and the balance of purified water, wherein the total amount is 100 parts. According to the application, the antioxidant property of the cream is improved by adding the vitamin E and the EDTA disodium, the vitamin E is used for directly scavenging free radicals, the EDTA disodium is used for eliminating an oxidation catalyst, and the quality guarantee period of the cream can be remarkably prolonged and the drug effect can be maintained by combining the vitamin E and the EDTA disodium.

The invention belongs to the technical field of cosmetics, and particularly discloses a freeze-dried powder base solution and a preparation method thereof. The freeze-dried powder base solution comprises a component A and a component B. The component A is prepared from magnesium potassium fluosilicate, a filling agent, lauroyl lysine, titanium dioxide, CI 77492, CI 77491, CI 77499 and the balance water, butanediol, xanthan gum, a thickening agent, trehalose, polysorbate-60, an emulsifying agent a, phenyl polytrimethylsiloxane, isononyl isononanoate and a preservative. The component B is prepared from the following components: the balance of water, butanediol, a preservative, magnesium sulfate, an emollient, disteardimonium hectorite, phenyl polytrimethylsiloxane, isododecane, trimethylsiloxy silicate ester, an emulsifier b and PEG-10 (Polyethylene Glycol) polydimethylsiloxane. Various raw materials are mixed, so that the obtained liquid foundation has relatively good dispersity, has smooth and refreshing skin feeling, and is prevented from being thick, sticky and greasy.

Provided herein are methods for precipitating proteins in compositions containing proteins and polysorbates. These methods allow for accurate determination of the concentration or amount of polysorbate in the composition.

The invention relates to the field of inorganic nonmetal powder materials, and discloses a preparation method of silicon nitride powder, which comprises the following steps: (1) mixing a surfactant, liquid ammonia and an organic solvent to form a to-be-reacted solution, and mixing the to-be-reacted solution with a silicon tetrachloride solution for substitution reaction to obtain a solution containing silicon imine suspended matters; the surfactant is selected from one or more of sodium dodecyl sulfate, polyvinylpyrrolidone, sodium stearate, sodium dodecyl benzene sulfonate, fatty acid methyl ester ethoxylate sulfonate, fatty acid sorbitan, polysorbate-20 and polysorbate-80; the surfactant is selected from one or more of sodium dodecyl sulfate, polyvinylpyrrolidone, sodium stearate, sodium dodecyl benzene sulfonate, fatty acid methyl ester ethoxylate sulfonate, fatty acid sorbitan, polysorbate-20 and polysorbate-80; (2) carrying out suspended matter extraction and impurity removal on the solution containing the silicon imine suspended matter to obtain silicon imine powder; (3) performing thermal decomposition on the silicon imine powder to obtain amorphous silicon nitride powder; and (4) crystallizing the amorphous silicon nitride powder to obtain the alpha-phase silicon nitride powder. The method can reduce the impurity content and agglomeration degree of the precursor so as to improve the quality of the silicon nitride powder.

The invention relates to the technical field of salad processing, in particular to mixed type composite salad sauce and a preparation method thereof.The mixed type composite salad sauce comprises salad base sauce, a thickening agent and composite edible powder which are packaged and stored separately and mixed during use, and the composite edible powder is obtained by spraying a protective agent to vegetable powder, nut powder, yoghurt powder, meat powder, fruit powder and cereal powder; the protective agent is obtained by mixing ethyl cellulose, polyethylene glycol, a dispersing aid and edible ethanol according to the weight ratio of (1-2): 0.5: 1: (5-6); the auxiliary dispersing agent is polysorbate and / or sodium carboxymethyl cellulose; the composite edible powder passes through a 200-500-mesh sieve, the salad dressing is divided into the salad base dressing, the thickening agent and the composite edible powder, the salad base dressing, the thickening agent and the composite edible powder are mixed during use, salad base dressing juice can be effectively prevented from directly permeating the composite edible powder, the vegetable powder and the fruit powder can keep the crispness of the salad base dressing, the nut powder cannot become greasy due to absorption of excessive grease, and the taste of the salad base dressing is improved. And the meat powder can maintain the due chewiness and flavor, so that the original crispness, tenderness, chewiness and flavor of the raw materials are maintained.

The application relates to the technical field of cough-relieving medicines, and discloses a high-efficiency cough-relieving loquat particle composition which is composed of the following components in parts by weight: loquat leaf extract 30-40 parts; white front extract 10-15 parts; platycodon grandiflorum extract 6-10 parts; white mulberry bark extract 18-25 parts; stemona sessiliflora extract 7-10 parts; menthol 0.1-0.5 part; polyethylene glycol 2-5 parts; mannitol 8-12 parts; ethyl cellulose 3-6 parts; hydroxypropyl methyl cellulose 1-3 parts; phosphatidylcholine 1-3 parts; polysorbate 80 1-3 parts; cross-linked sodium carboxymethyl cellulose 4-6 parts; and sucrose 40-60 parts. The double dispersion system combining the immediate-release component and the sustained-release component is adopted, the solubility and the initial release speed of the traditional Chinese medicine extract are remarkably improved through the addition of polyethylene glycol and mannitol, and the technical effect that the drug effect appearing time is remarkably shortened is achieved. Compared with the technical scheme relying on only a single release mode in the prior art, the deficiency that the drug effect is slow and the symptoms of the patient cannot be timely relieved is solved.

The invention discloses an enconazole self-emulsifying drug delivery system composition and a preparation method thereof, and belongs to the technical field of medicines. The enconazole self-emulsifying composition is prepared from enconazole, an oil phase and an emulsifying agent, the oil phase is sorbitan fatty acid esters; the emulsifying agent is polysorbate; the sum of the sorbitan fatty acid esters and the polysorbates is greater than or equal to 10% and less than 100%. After the self-emulsifying composition is dispersed in water, the particle size is not higher than 10 microns, and after the self-emulsifying composition is stored for 6 weeks at room temperature, the enconazole is not degraded and is uniformly dispersed in an emulsified solution, and the stability is good.

The application discloses a kind of bumetanide tablets, raw materials include bumetanide 1 according to mass ratio;Corn starch 81~85;Lactose 50~54;Agar 0.1~0.3;Povidone K304~6;Polysorbate 80, 0.1~0.2;Silicon dioxide 3~4.5;Talcum powder 2~3.3;Magnesium stearate 0.3~0.7.Its preparation method includes the following steps: pretreatment, premixing, granulation, wet granulation, drying, dry granulation, total mixing, tabletting and packaging.The application introduces the synergistic system of trace agar and polysorbate 80 in the prescription.Agar, as a natural hydrophilic colloid, can form a hydrophilic network structure during the granulation process, and synergistically act with polysorbate 80, greatly improving the wettability and dispersibility of the slurry to ultrafine bumetanide, preventing drug agglomeration, so that the drug can be more evenly distributed in the granules during the subsequent drying and tabletting process.

The invention discloses an oyster enzymolysis ultrafiltration extract nasal spray and a preparation method thereof, the nasal spray comprises the following components: 5-10 wt% of oyster extract, 0.1-0.3 wt% of preservative, 0.05-0.15 wt% of sodium chloride and 0.1-0.3 wt% of emulsifier, the pH value is 5.5-6.5, the content of the preservative is 0.1-0.3 wt%, the content of the sodium chloride is 0.05-0.15 wt%, the content of the emulsifier is 0.1-0.3 wt%, and the balance is water. The preservative is one of benzalkonium chloride, sorbic acid and potassium sorbate, and the emulsifier is polysorbate 80. Through definite raw material composition, a step-by-step process and quality control, the bioavailability of active components is improved, the flavor of the product is optimized, the effect of safely and efficiently improving sleep is achieved, the problems of low bioavailability, poor flavor and potential safety hazards of an existing sleep improving product are solved, the process repeatability is high, and the preparation method is suitable for industrial production. The long-term use of people with chronic insomnia is facilitated.

The present application relates to string maintenance nanoemulsion and its preparation method, belong to string maintenance technical field. The nanoemulsion includes: polysorbate 80, stearic acid sorbitan 60 as main emulsifier, glycerin monostearate, cetyl alcohol, stearyl alcohol as auxiliary emulsifier, liquid paraffin, xanthan gum adjusts consistency, chitosan carries sodium hyaluronate nanoparticle as long-acting moisturizing agent, glycerol, propylene glycol is humectant and can be used as antifreezing agent; hydroxyphenyl ethyl as preservative; can also selectively add essence, the balance is water. The water-soluble ingredients are mixed and stirred uniformly; the oil-soluble ingredients are mixed and stirred uniformly; the oil phase is added to the water phase, and the primary emulsion is stirred and emulsified, and the essence is added after cooling, and the present application is obtained. The present application realizes long-acting moisturizing and nourishing of the string by introducing chitosan carrying sodium hyaluronate nanoparticles, and has the advantages of fine texture, softness and the like.

This application relates to the field of feed processing technology and discloses a highly absorbable feed composition for nursery pigs containing compound probiotics. The composition includes the following ingredients: a basal diet, a live bacteria compound powder composed of freeze-dried *Lactobacillus plantarum* powder and freeze-dried *Bacillus coagulans* powder, medium-chain triglycerides, a PIT-responsive compound emulsifier composed of polysorbate-80 and sorbitan monooleate, anhydrous trehalose, glycerol, a micron-sized confinement carrier, which is a porous carrier obtained by high-temperature expansion and vacuum degassing of perlite powder, and fumaric acid. This invention employs anhydrous trehalose and glycerol to construct a high-permeability system, combined with medium-chain triglycerides and a compound emulsifier to form an oil-phase encapsulation, achieving the technical effect of effectively blocking external moisture penetration and improving the heat resistance of the bacteria.

The invention provides a preserving fluid for preserving adipose tissue-derived stem cell extracellular vesicles and a formula of a corresponding preparation, and particularly, the formula comprises sodium chloride, cane sugar, polysorbate 80, histidine and histidine hydrochloride. According to the formula, the storage stability of the extracellular vesicles secreted by adipose tissue can be improved, substances in the extracellular vesicles are prevented from being degraded, convenience is provided for clinical application of the extracellular vesicles, and good market prospects are achieved.

The present application belongs to the technical field of biological enzyme preservation, and particularly relates to a bromelain freeze-drying protective agent and a preparation method thereof. The composition comprises the following components: 30-50 parts of trehalose, 8-10 parts of pullulan, 3-10 parts of malt dextrin, 12-22 parts of mannitol, 1-4 parts of sorbitol, 4-12 parts of glycine, 0.05-0.2 parts of polysorbate-20, 1.5-4.5 parts of a buffer, 0.2-0.8 parts of N-acetylcysteine, 0.05-0.3 parts of oxidized glutathione, 0.8-2.5 parts of PEG and 0.05-0.3 parts of an antioxidant. The present application takes trehalose-pullulan polysaccharide as a main skeleton, inhibits ice crystal growth and reduces water activity; mannitol constructs a crystal phase support network, and polysorbate-20 stabilizes the interface; oxidized glutathione temporarily seals mercapto groups, and microencapsulated N-acetylcysteine realizes controllable reduction during redissolution; and a sodium phosphate buffer system maintains pH stability.

The present disclosure relates to formulations comprising a protein comprising an Fc region (e.g., an antibody) and a surfactant such as a polysorbate (e.g., Polysorbate 20), and methods of purifying such proteins that improve stability of the surfactant such as a polysorbate in such formulations.

The invention relates to the technical field of biological materials, and discloses a liquid dressing and a preparation method thereof, and the liquid dressing comprises a lipid phase and a water phase; the lipid phase comprises lecithin, glyceryl dioleate, polysorbate and an organic solvent; the water phase comprises hyaluronic acid or a salt thereof and a buffer solution, the molecular weight of the hyaluronic acid or the salt thereof is 500-5000Da, and the mass ratio of the hyaluronic acid or the salt thereof to lecithin is (0.05-0.2): 10. The mode of combining the lipid phase and the water phase is adopted, all components in the lipid phase and the water phase have a synergistic effect, free hyaluronic acid or salt thereof is released while the carrier transports hyaluronic acid or salt thereof, the free hyaluronic acid or salt thereof preferentially reaches an action target spot, and then the hyaluronic acid or salt thereof is slowly released under the carrier effect of the lipid phase, so that the hyaluronic acid or the salt thereof is slowly released. According to the present invention, the long-term and lasting protection on the wound part is achieved, the rapid release and slow release combined purpose is achieved, the in vivo immune system is enhanced, the overall cell inflammatory factor level in the body is significantly reduced, and the rapid and continuous pain relieving effect is achieved.

The invention relates to the technical field of synthetic leather preparation, and discloses waterborne polyurethane synthetic leather and a preparation method thereof.The waterborne polyurethane synthetic leather comprises a base layer and a coating layer, the base layer is polyester non-woven fabric, and the coating layer comprises, by weight, 10-20 parts of aromatic isocyanate; 50 to 70 parts of polyether polyol; 5 to 15 parts of nano silicon dioxide; 0.1 to 0.5 part of a catalyst; 15 to 25 parts of water; 5 to 10 parts of epoxidized soybean oil; 0.1 to 0.3 part of polysorbate-20 (20); the aromatic isocyanate is toluene diisocynate, the nitrogen content of the aromatic isocyanate is 14-16%, the purity of the aromatic isocyanate is higher than 98%, and the volatile content of the aromatic isocyanate is lower than 1%. By introducing the nano silicon dioxide and the epoxidized soybean oil and optimizing the reaction process, the anti-aging, anti-ultraviolet and high-temperature-resistant properties of the polyurethane synthetic leather are improved, the service life is prolonged, and the stability and high performance of the product are ensured.