97 results about "Tocopherol" patented technology

The invention relates to the technical field of rice bran processing, and discloses a rice bran degreasing and nutrition retention edible process synergistic treatment method which comprises the following steps: (a) in an NADES-aqueous solution medium, adding an immobilized catalyst A, and hydrolyzing ferulate bonds and phospholipids in rice bran at low temperature; (b) carrying out intermediate dehydration on the slurry obtained in the step (a) to reduce the water activity; (c) adding an immobilized catalyst B into the dehydrated slurry in the step (b), carrying out esterification reaction, and grafting free ferulic acid generated by hydrolysis to glyceride in situ; and (d) carrying out solid-liquid separation on the slurry obtained in the step (c) to obtain finished oil and finished powder. According to the method, an NADES medium is adopted to replace an organic solvent, the whole process is carried out at low temperature, degradation of heat-sensitive nutrient substances is avoided, and resource utilization of ferulic acid is achieved. The prepared functional rice bran oil is rich in feruloyl glyceride, total tocopherol and oryzanol, and is low in acid value and peroxide value.

This invention discloses a recombinant collagen liposome, its preparation method, and its application. The recombinant collagen liposome comprises 1-10 parts recombinant type XVII collagen, 2-15 parts soybean lecithin, 0.3-2 parts tocopherol, 0.5-7 parts antioxidant, 20-54 parts glycerol, and Dendrobium officinale enzymatic hydrolysate to a total weight of 100 parts. This invention improves the stability and transdermal absorption of recombinant type XVII collagen by encapsulating it in liposomes. The prepared recombinant collagen liposomes not only have a high encapsulation efficiency but also retain excellent barrier repair and anti-wrinkle effects after 8 weeks of storage, making them suitable for use in cosmetics.

The invention discloses a self-emulsifying adjuvant of a vaccine and a preparation method of the self-emulsifying adjuvant, and relates to the technical field of vaccine adjuvants. The adjuvant comprises an oil phase, an emulsifier and a freeze-drying protective agent, the oil phase comprises squalene and tocopherol, the emulsifier comprises polysorbate and a polyoxyethylene-polyoxypropylene block copolymer, and the freeze-drying protective agent comprises sugar and sugar alcohol. The preparation method comprises the following steps: emulsifying an oil phase and a water phase to form a nano-emulsion, and then freeze-drying to obtain freeze-dried powder. The adjuvant has the advantages of small particle size, uniform distribution, high stability, rapid reconstruction and the like, and can effectively maintain active components and improve the immune effect of vaccines.

The invention discloses a compound microorganism freeze-drying protective agent, a preparation method of the compound microorganism freeze-drying protective agent and a use method of the compound microorganism freeze-drying protective agent. Comprising the following raw materials in parts by weight: 0.03 part of disodium ethylene diamine tetraacetate, 5 to 15 parts of trehalose, 2 to 5 parts of sorbitol, 0.5 to 2 parts of ascorbic acid, 0.05 to 0.2 part of N-acetyl-L-cysteine, 0.1 to 0.5 part of polylactic acid-glycolic acid copolymer, 0.01 to 0.05 part of alpha-tocopherol and 1 to 3 parts of bentonite. The PLGA, the alpha-tocopherol and the NAC construct a three-stage synergistic anti-oxidation system from outside to inside: the PLGA is externally blocked, so that rapid consumption of an antioxidant is avoided, and slow release is realized; the alpha-tocopherol realizes oxidative damage repair of cell membranes; nAC maintains the internal reduction environment of cells, reduces oxidative stress and can regenerate alpha-tocopherol at the same time, and reutilization of resources is achieved.

Disclosed is a method of reducing fine lines or wrinkles on skin. The method can include applying a topical skin care composition to skin with fine lines or wrinkles. The composition can include lactobacillus ferment, ascorbyl glucoside, Terminalia ferdinandiana fruit extract, Helianthus annuus (Sunflower) seed extract, glycerin, Persea gratissima (avocado) oil, Butyrospermum parkii (shea) butter, coco-caprylate / caprate, Sclerotium gum, sodium benzoate, and tocopherol.

The invention discloses an essence composition for promoting eyelash growth and a preparation method thereof.The essence composition comprises a phase A, a phase B, a phase C, a phase D and a phase E. The phase B comprises natural active extracts. The natural active extract comprises butyrospermum parkii butter, a matricaria chamomilla leaf extract, glycyrrhiza glabra, a centella asiatica extract, a rosemary leaf extract, tocopherol, a scutellaria baicalensis root extract, a tea leaf extract and a polygonum cuspidatum root extract in a mass ratio of (0.488985): (0.005): (0.0025): (0.0025): (0.0005): (0.0005): (0.000005): (0.000005): (0.000005). On the premise that safety and mildness are guaranteed, the eyelash density and length are remarkably improved through low-dosage active ingredients, and the safe and efficient requirements of daily eyelash nursing can be met.

To provide a sirolimus-containing powder granule formulation that ensures bioavailability and has improved stability. [Solution] A sirolimus-containing granular preparation containing sirolimus and tocopherol, but not containing hydroxypropylcellulose, and a method for producing a sirolimus-containing granular preparation, characterized by comprising the steps of (1) mixing a solution containing sirolimus and tocopherol with core particles that form the core of the granular preparation in the absence of hydroxypropylcellulose, and (2) drying the mixture obtained in step (1).

The invention discloses a fried crisp meat wrapping material and application thereof, and belongs to the technical field of food. The fried crisp meat wrapping material is prepared from the following raw materials in parts by weight: 80 parts of wheat flour, 20 parts of waxy corn starch, 150 parts of water, 0.75 part of xanthan gum and 0.05 part of tocopherol. The fried crispy meat prepared by the method disclosed by the invention has relatively low oil content, meanwhile, the quality of frying oil can be maintained to a certain extent in the frying process, and potential food safety hazards are reduced. The crispy meat shells fried with the wrapping material prepared by the method have better health attributes and better palatability, and based on the oxidation resistance of tocopherol in the shells, the crispy meat shells have important significance for maintaining body health and preventing diseases.

The invention discloses an optimized formula of plant organic nano-selenium for activating an immune system, inhibiting cancer cell proliferation, preventing cancers, preventing tumors, resisting oxidation and resisting aging, and belongs to the technical field of functional food formulas. According to the formula, selenium-enriched yeast and dl-alpha-tocopheryl acetate are used as main materials, L-ascorbic acid can be selectively added, auxiliary materials such as microcrystalline cellulose and starch sodium octenylsuccinate are matched to prepare a capsule preparation, and the content of functional components in a single preparation is precisely controlled as follows: 90-100 micrograms of selenium and 40-50 mg of vitamin E, or 90-100 micrograms of selenium, 40-50 mg of vitamin E and 40 mg of vitamin C. According to the invention, synergistic interaction is realized through scientific proportioning of functional components, a fat-soluble and water-soluble dual anti-oxidation system is constructed, an organism immune system can be effectively activated, cancer cell proliferation can be inhibited, and meanwhile, the composition has multiple effects of preventing cancers, preventing tumors, resisting oxidation and resisting aging; the preparation method is simple and convenient in process, easy in parameter control and suitable for industrial large-scale production, the prepared preparation is high in active ingredient stability, excellent in bioavailability, high in safety and capable of being widely applied to preparation of related functional foods, and all raw materials are food-grade. The technical problems that an existing selenium compound formula is unreasonable in proportion, poor in efficacy synergy and poor in preparation performance are solved.

The present disclosure includes chewing gum base compositions and related methods of use and preparation thereof. For example, the present disclosure includes a chewing gum base composition comprising from about 25% to about 50% by weight of a natural rubber composition, from about 20% to about 35% by weight of a resin, from about 15% to about 25% by weight of a filler, from about 15% to about 20% by weight of a softener, from about 15% to about 20% by weight of a plasticizer, and from about 2% to about 10% by weight of an emulsifier. The natural rubber composition may include at least 99% by weight of edible deproteinized natural rubber, and the edible stabilizer includes an antioxidant selected from the group consisting of butylated hydroxytoluene (BHT), tocopherol, or a combination thereof.

The application belongs to the technical field of biological medicine, and particularly relates to an adjuvant influenza vaccine and a preparation method and application thereof. The adjuvant influenza vaccine comprises an influenza virus monovalent stock solution, an adjuvant and a PBS buffer solution; the adjuvant is prepared by using mixed oil and an auxiliary agent, the mixed oil comprises squalene, medium-chain triglyceride and alpha-tocopherol; and the auxiliary agent comprises sorbitan trioleate Span-85, Tween 80 and vitamin E succinate polyethylene glycol ester. The adjuvant influenza vaccine prepared by the application has good immunization effect, and can especially improve the overall effect of a tetravalent adjuvant influenza vaccine on four viruses.

The present invention relates to a composition comprising certain triglycerides having a low content of cyclopropene-based fatty acid (CPFA) acyl groups and tocopherols, as well as the use of such a composition, especially in cosmetic applications, and a method of treating baobab oil.

The present invention relates to a nutritional vitamin complex for pets intended to improve the fur and skin quality of pets such as dogs and cats. The composition of the complex contains omega-3, curcumin, piperine, biotin (vitamin H or vitamin B7), vitamin B2 (riboflavin), vitamin B3 (nicotinic acid or niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B12 (cyanocobalamin), folic acid (vitamin B9), vitamin E (alpha-tocopherol), vitamin C, zinc (zinc glycine chelate), coenzyme Q10, hydrolysed type II collagen, astaxanthin, DL-methionine, selenium, L-glycine, L-proline, L-phenylalanine, L-leucine, L-isoleucine, L-histidine, L-arginine, L-lysine, L-tyrosine, resveratrol, and a flavouring agent.

The invention provides a thermo-sensitive hydrogel containing alpha-isoterpinene and a preparation method of the thermo-sensitive hydrogel, and the hydrogel comprises the following components: Te with the content of 0.1-5.0% (w / w); the temperature-sensitive matrix is composed of poloxamer 407 (15-25% w / w) and poloxamer 188 (2-10% w / w), and the mass ratio of the poloxamer 407 to the poloxamer 188 is (2.5-7.5): 1; the antioxidant system comprises ascorbyl palmitate (0.05-0.2% w / w), at least one of tocopherol, rosmarinic acid ester or pharmaceutically acceptable derivatives of the rosmarinic acid ester, and the balance of water. The traditional Chinese medicine composition is used for safely and effectively treating acnes. Belongs to the field of pharmaceutical preparations.

The object of this disclosure is to provide a topical composition comprising ceramide 2 and tocopherol and / or its derivatives that can suppress creaming. [Solution] A topical composition containing (A) ceramide 2, (B) tocopherol and / or its derivatives, and (C) heparin-like substance has suppressed creaming.

The present invention relates to a nutritional vitamin complex for pets intended to improve the fur and skin quality of pets such as dogs and cats. The composition of the complex contains omega-3, curcumin, piperine, biotin (vitamin H or vitamin B7), vitamin B2 (riboflavin), vitamin B3 (nicotinic acid or niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B12 (cyanocobalamin), folic acid (vitamin B9), vitamin E (alpha-tocopherol), vitamin C, zinc (zinc glycine chelate), coenzyme Q10, hydrolysed type II collagen, astaxanthin, DL-methionine, selenium, L-glycine, L-proline, L-phenylalanine, L-leucine, L-isoleucine, L-histidine, L-arginine, L-lysine, L-tyrosine, resveratrol, and a flavouring agent.

The invention belongs to the technical field of health-care products, particularly relates to plant extract wormwood oil for body oil bath and a preparation process thereof, and provides a safe and efficient solution through compounding of natural plant essential oil and low-temperature process innovation. The prunus amygdalus dunn oil and the simmondsia chinensis seed oil are used as mild substrates, and cooperate with the lavender oil, the blumea oil and the rose essential oil to form a double-effect synergistic system for soothing nerves and dredging collaterals; the completeness of plant active molecules is reserved to the maximum extent through gradient mixing and light-shielding curing procedures, an anti-oxidation barrier is constructed by means of natural tocopherol, and the product stability is prolonged. The technical effects comprise that the lavender oil and the rose essential oil calm the nervous centralis, relieve anxiety mood and realize synchronous regulation of mind and body; the simmondsia chinensis seed oil bionic sebum structure promotes zero-burden permeation, and the prunus amygdalus dulcis oil forms a protective film to reduce scraping injury and improve the universality of sensitive skin.

The present application relates to the field of livestock feed, and provides a feed for improving the intestinal health of livestock by rosemary oil and a preparation method thereof; the feed is composed of cyclodextrin-coated rosemary oil compound, corn flour, straw pellets, wheat, barley, rapeseed meal, cottonseed meal, peas, bran, bone meal, calcium carbonate, calcium hydrogen phosphate and the like. The cyclodextrin-coated rosemary oil compound is obtained by co-precipitation of rosemary essential oil nano-composite emulsion and cyclodextrin, and the rosemary essential oil nano-composite emulsion is mainly obtained by nano-emulsification of rosemary, alpha-tocopherol and chitosan; the above technologies significantly enhance the stability, slow-release performance and absorption rate of rosemary oil in the feed. The feed is uniformly mixed and granulated by a double-shaft paddle mixer, and the feed not only improves the intestinal health of livestock and enhances the nutrient absorption efficiency, but also has good processability, storage stability and long-term performance.

This invention provides a composition with moisturizing and skin-nourishing effects and its application. The composition comprises collagen, sodium hyaluronate, shea butter, and tocopherol. The collagen includes any one or a combination of at least two of recombinant human type III collagen, recombinant human type IV collagen, or recombinant human type XVII collagen. This invention creatively discovers that the four components—collagen, sodium hyaluronate, shea butter, and tocopherol—can positively influence each other and synergistically enhance their effects, significantly increasing the moisture content of the stratum corneum and improving skin elasticity, thus achieving excellent moisturizing, antioxidant, and skin-nourishing effects.

This invention discloses a method for preparing and using a long-acting antitumor organic and inorganic bone binder, which is prepared by polymerization, blending, and freeze-drying of porous calcium phosphate and antioxidant-grafted Tremella fuciformis polysaccharide hydrogel. The porous calcium phosphate is prepared by controlling its porous structure and composition to achieve degradation, thereby slowly releasing calcium ions, improving osteogenic properties, and achieving high bonding strength with human bone at the postoperative bone tumor defect site. Simultaneously, leveraging the high bonding strength and long-acting antitumor properties of the Tremella fuciformis polysaccharide hydrogel grafted with one or two antioxidants such as ascorbic acid, tea polyphenols, flavonoids, and tocopherols, the porous calcium phosphate and antioxidant-grafted Tremella fuciformis polysaccharide hydrogel are combined to form a covalently cross-linked network structure, further improving the bonding strength of the bone binder, promoting osteogenic properties with host bone tissue, and providing a long-lasting antitumor cycle.

The invention belongs to the technical field of cosmetics, and particularly relates to an oil-soluble composite plant extract as well as a preparation method and application thereof. The oil-soluble composite plant extract is prepared from the following components in percentage by mass: 0.8 to 1.2 percent of chamomilla recutita flower extract, 0.4 to 0.8 percent of glycyrrhiza glabra root extract, 0.4 to 1.0 percent of peony extract, 0.3 to 0.7 percent of herba centellae extract, 0.08 to 0.12 percent of rosemary leaf extract, 0.08 to 0.12 percent of tocopherol, 0.0010 to 0.0014 percent of tea leaf extract, 0.0010 to 0.0016 percent of rhizoma polygoni cuspidati root extract, 0.0010 to 0.0014 percent of radix scutellariae root extract and the balance of butyrospermum parkii butter. By optimizing the preparation method of the peony extract, the content of total polyphenols in the peony extract is increased. The oil-soluble composite plant extract is applied to skin care products and has the effects of improving skin elasticity and resisting aging.

Disclosed herein are personal care compositions having enhanced antioxidant efficacy and are mild to the skin. According to one aspect, there is provided a personal care composition having from about 0.1 to about 9 wt.% of vitamin E, the vitamin E comprising tocopherols; from about 1 to about 10 wt.% of vitamin B, the vitamin B comprising nicotinamide; and an extract of Amaranthus sp., wherein all weight percents are based on the total weight of the personal care composition.

This invention discloses an artificial breeding method for the Oriental blackfish, belonging to the field of fish artificial breeding technology. It includes six core steps: broodstock selection and domestication, enhanced maturation cultivation, broodstock selection and anesthesia, spawning induction, artificial insemination, fertilized egg hatching, and fry rearing. One year in advance, suitable-aged wild Oriental blackfish are selected and domesticated in a flowing water pond. Before breeding, tocopherol is mixed into their feed to enhance gonadal development. High-quality broodstock are selected at a female-to-male ratio of 1:2 and anesthetized. A specific ratio of spawning inducing agent is injected using a two-injection method. Artificial insemination is performed in a standardized fiberglass circular fishpond under controlled water flow conditions. Fertilized eggs are incubated at 26±1℃ for 22 hours, and after hatching, they are transferred to a sterilized micro-flow water pond for rearing. This invention achieves a 100% spawning efficiency, a stable fertilization rate of over 95%, and a hatching rate exceeding 82%. It is simple to operate, cost-effective, and allows for large-scale breeding, providing key technical support for the conservation and population expansion of the Oriental blackfish.

Disclosed is a method of reducing fine lines or wrinkles on skin. The method can include applying a topical skin care composition to skin with fine lines or wrinkles. The composition can include Terminalia ferdinandiana fruit extract, Helianthus annuus (Sunflower) seed extract, sodium hyaluronate, arginine, glycerin, pentylene glycol, lecithin, and tocopherol or tocopherol acetate.

The invention discloses a melogabalin besylate-containing pharmaceutical composition and a preparation method thereof, the preparation prescription adopts vitamin E polyethylene glycol succinate, gallic acid or tocopheryl succinate as antioxidants, and the specific antioxidants are screened out, so that the prepared melogabalin besylate pharmaceutical composition is better in stability and better in curative effect. Oxidative degradation impurities are effectively controlled, and the effectiveness and safety of melogabalin besylate are improved. In addition, the preparation method is stable, controllable and easy to amplify.

The present invention relates to a composition comprising: a) at least one agent chosen from acids and salts thereof, the acids comprising at least one linear or branched, saturated or unsaturated, aliphatic chain containing from 3 to 5 carbon atoms; b) at least 0.2% by weight, relative to the total weight of the composition, of at least one antioxidant chosen from tocopherols and esters thereof; and c) at least one surfactant chosen from anionic surfactants, amphoteric or zwitterionic surfactants, and mixtures thereof.

The invention relates to the technical field of preparation of cleansing products, in particular to a formula and a preparation method of skin-refreshing cleansing oil, and the skin-refreshing cleansing oil is characterized in that fatty acid ester components and polyoxyethylene ether surfactants in a system are balanced by adjusting the proportion of cetyl alcohol ethyl hexanoate to PEG-8 diisostearate; after the proportion is adjusted, the dosage of sorbitol polyether-30 tetraoleate is increased to 7%, and the strength of an interfacial film is improved; and tocopherol is added as an antioxidant substance, so that the risk of emulsification collapse caused by oxidation stability is reduced. According to the skin-refreshing cleansing oil formula and the preparation method, the strength of an interfacial film is enhanced by increasing the dosage of sorbitol polyether-30 tetraoleate, oxidation is inhibited by adding tocopherol, the content of squalane is dynamically adjusted by combining the proportion of polar / non-polar components, emulsification collapse and layering are effectively avoided, and it is ensured that the product is kept in a stable state in the storage and use process.

The invention relates to a pharmaceutical dosage form for oral administration comprising (i) an intragranular phase, which comprises Sertraline or a physiologically acceptable salt thereof; one or more intragranular fillers (preferably selected from one or more sugar alcohols or sugars; preferably mannitol or lactose, more preferably mannitol); one or more intragranular antioxidants (preferably selected from butylated hydroxytoluene (BHT), butylated hydroxy anisole (BHA), tocopherol or derivatives thereof, ascorbic acid or derivatives thereof, sodium metabisulphite, propyl gallate, sodium thiosulphate, or any combination thereof, more preferably ascorbic acid); (ii) an extragranular phase, which comprises one or more extragranular fillers (preferably mannitol, microcrystalline cellulose, lactose, or any combination thereof); and (iii) optionally, a film coating. The invention further relates to a process for manufacture by wet granulation, wherein the antioxidant is preferably dissolved in the granulation liquid.

To provide a retort food oil and fat composition that can preserve the desirable original flavor of retort food even when stored for a long period of time, and a retort food using the retort food oil and fat composition. [Solution] A retort food oil composition wherein the total oil composition contains 0.015 to 15% by weight of tocopherol, 0.0005 to 0.15% by weight of mushroom extract (dry weight), and the weight ratio of tocopherol to mushroom extract is 8 to 250.

The invention discloses cactus essence oil with an anti-wrinkle effect and a preparation method of the cactus essence oil, and belongs to the technical field of skin care. Comprising the following raw materials: prickly pear seed oil, simmondsia chinensis seed oil, squalane, caprylic / capric triglyceride, bakuchiol, rosa damascena flower oil, sandalwood oil, frankincense oil, carrot seed oil, pelargonium graveolens oil, bisabolol, crithmum maritimum oil and tocopherol. According to the cactus essence oil with the anti-wrinkle effect and the preparation method of the cactus essence oil, the cactus seed oil is used as a core substrate, core components such as bakuchiol and crithmum maritimum oil are scientifically matched with soothing components such as bisabolol, and special preparation processes such as low-temperature premixing, step-by-step mixing, vacuum homogenization and light-shielding standing are combined, so that the cactus essence oil with the anti-wrinkle effect is obtained. The prepared cactus essence oil realizes multiple improvements of wrinkle resistance, stability maintenance, skin feeling and production practicability.