55 results about "Thiamine" patented technology

A sunscreen formulation includes carbon quantum dots having reacted units of citric acid and thiamine and particles of a metal-organic framework including zinc and reacted units of terephthalic acid. The sunscreen formulation further comprises a liquid carrier and a stabilizer. The quantum dots are dispersed in the metal-organic framework. The particles of the metal-organic framework are dispersed in the liquid carrier.

The present disclosure relates generally to methods of utilizing sonosensitizers in the presence of thiamine or a derivative thereof for the purpose of cross-linking animal tissue, producing singlet oxygen within or at the site of animal tissue, or treating a condition in a subject, wherein the condition is an aneurysm, cancer, and / or a scleral condition.

The invention discloses application of thiamine in preparation of a product for treating subclinical ketosis of dairy cows, and belongs to the field of biological medicines. Tests prove that compared with dairy cows suffering from subclinical ketosis (SCK), by adding thiamine, the content of beta-hydroxybutyric acid (BHBA), the number of bacteria in milk and the number of somatic cells can be remarkably reduced, and the milk yield, the milk fat content, the acetic acid content and the A / P ratio are remarkably increased; the microbial diversity of rumen and excrement of the dairy cow can be adjusted; a metabonomics result shows that metabolite up-regulated after the thiamine is added mainly focuses on pyruvic acid metabolism, glycolysis or gluconeogenesis, tyrosine metabolism, glycerophospholipid metabolism and biosynthetic pathways of phenylalanine, tyrosine and tryptophan. The conclusion is that when thiamine is added into the SCK dairy cow, synthesis and catabolism of BHBA of an organism can be effectively regulated and controlled by adjusting the content of succinyl-coenzyme A, then subclinical ketosis is relieved, rumen fermentation is promoted, and therefore the milk yield and the milk quality are improved.

The invention relates to a thiazole connection-based covalent organic framework nanofiltration membrane as well as a preparation method and application thereof. Amphiphilic thiamine-containing monomers and aldehyde monomers are used as interfacial polymerization monomers, and polymerization is performed on a liquid-liquid free interface to obtain the covalent organic framework nanofiltration membrane with thiazole bonds as connecting structure elements. The thiazole bond is used as a connecting element to improve the separation selectivity and acid resistance of the COF membrane, the molecule desalination selectivity of the thiazole-connected covalent organic framework nanofiltration membrane reaches 690, and the thiazole-connected covalent organic framework nanofiltration membrane can be stably stored for a long time in 12M HCl, can still stably run and be stored for a long time under the harsh conditions of mechanical stress, high temperature, strong corrosion and the like, and keeps excellent structural stability; the membrane can be used for membrane separation in a neutral environment or a strong acid environment.

The present application provides thiamine compounds shown in formula (I) and application thereof. The thiamine compounds of the present application can be used for preparing polyolefin antioxidants. The thiamine compounds of the present application introduce sulfide bonds in aryl secondary amine, so that the antioxidant contains naphthylamine groups of primary antioxidants and sulfide groups of auxiliary antioxidants, which not only can terminate free radicals by providing hydrogen protons, but also can react with hydroperoxides, so as to achieve the dual effects of primary and auxiliary antioxidants, and thus the antioxidant effect is significantly enhanced.

The present invention provides a thiamine sulfate crystal and an extraction method thereof, and relates to the technical field of thiamine sulfate purification, and the extraction method comprises the following steps: thiamine thiosulfate is oxidized by hydrogen peroxide to obtain an oxidation liquid, and the oxidation liquid is added into an organic solvent for crystallization and separation to obtain the thiamine sulfate crystal; the organic solvent comprises at least one of methanol, ethanol and acetone. According to the extraction method, the specific organic solvent is adopted to crystallize the thiamine sulfate, high-purity thiamine sulfate crystals can be extracted from the aqueous solution oxidized by thiamine thiosulfate, the purity can reach 99.70% or above, and the process is simple, efficient and suitable for industrial production.

The present invention includes at least a coloring material, water, thiamine, a thiamine derivative, or a salt thereof.

The application discloses a fermentation method for producing thiamine pyrophosphokinase and belongs to the technical field of bioengineering. The BL21 recombinant engineering bacteria containing pET28a-TPK, pET28a-ProS2-TPK or pET28a-SUMO-TPK are constructed, the seed liquid is prepared, the isopropyl-beta-D-thiogalactoside is used for inducing expression, the bacteria are collected, the cells are broken and the supernatant is collected to obtain the TPK crude enzyme liquid. In the fermentation, the LB / TB culture medium containing 50 μg / mL kanamycin or 100 μg / mL ampicillin is used. The SUMO label is introduced to guide the correct folding of the TPK, so that the soluble expression ratio of the TPK is more than 85%, the ratio is improved by 2 times compared with the common system, the inclusion body ratio is greatly reduced, the process is stable and has good repeatability, and an effective scheme is provided for the industrialized large-scale preparation of the TPK.

The invention relates to the technical field of powder conveying, and particularly discloses a thiamine nitrate finished product powder automatic conveying and quantitative discharging system which comprises a discharging pipe assembled below a powder hopper, and an elastic pressing piece, a pressing push ring and a control assembly are arranged on the discharging pipe; the multiple elastic pressing pieces are arranged in the circumferential direction of the discharging pipe, each elastic pressing piece comprises a connecting part fixedly connected with the discharging pipe and a movable part located below the connecting part, and the lower end of each movable part is obliquely arranged outwards in the radial direction; the pressing push ring sleeves the outer side of the connecting part in an up-down sliding manner; the control assembly is arranged at the discharging end of the discharging pipe and corresponds to the lower end of the movable part in position. The thiamine nitrate finished product powder automatic conveying and quantitative discharging system has the effects that dust diffusion can be effectively reduced, and meanwhile the powder bagging quality is improved.

The present disclosure provides compositions and methods for providing a health benefit to a growing animal comprising administering a food composition to the animal, wherein the food composition includes a brain development blend. The brain development blend generally comprises DHA, EPA, taurine, choline, thiamine, riboflavin, pantothenic acid, niacin, pyridoxine, vitamin B12, and folic acid.

The invention discloses a preparation method of deep-color isopropyl ethyl thiamine ester, which comprises the following steps: taking 200g of isopropyl ethyl thiamine ester base material, adding 5g of 8% hydrogen peroxide (the effective HO accounts for 0.2%) under the stirring conditions of 35 DEG C and 250rpm, stirring for 10 minutes, adding 0.3-3.4 g of 70% monoethylamine, and reacting at constant temperature for 30 minutes to obtain a deep-color isopropyl ethyl thiamine ester product. According to the method, continuous controllable change of the color of the thiamine ester from light red yellow to dark red brown is realized by accurately controlling the ratio and the reaction condition at 35 DEG C, the deviation of the main peak of the product chromatography is less than or equal to 0.5%, layering and precipitation are avoided after standing in a dark place for 8 hours, the loss of main components is extremely low, the process stability is high, and the method is suitable for industrial production.

The invention discloses a nutritional additive for livestock, which is prepared from thiamine and nicotinamide in a mass ratio of (1-2): (1-2), and is a brand-new nutritional additive capable of effectively relieving the industrial problems of sheep breast immunity, oxidative damage, lactation performance reduction and the like caused by heat stress. Under the optimized additive amount, by applying the nutritional additive, the functions of mammary gland cells can be remarkably improved, and the milk yield and the content of milk components such as milk fat, milk protein and lactose can be increased; according to the nutritional additive, a safe and stable daily ration formula can be established, and the residual risk of traditional chemical drugs or excessive vitamins is avoided.

The present application provides a preparation method of thiamine compound shown in formula (I), wherein the method comprises using compound of formula (III) and R 15 X is used to prepare thiamine compound shown in formula (I),

The present invention relates to the use of a combination of vitamins, more specifically to the combined use of biotin and thiamine, for the treatment of Huntington's disease. More specifically, the present invention explains that treatment with a combination of biotin and thiamine can improve the neurological, neuroimaging and spectroscopic symptoms associated with Huntington's disease.

The invention discloses a formula of an organic mixed health-care beverage and a preparation method of the organic mixed health-care beverage. The raw materials comprise, by weight, 1-3 g of ginseng, 1-3 g of deer-horn glue, 2-5 g of folium cortex eucommiae, 2-5 g of gynostemma pentaphylla, 2-5 g of hawthorn, 2-5 g of ligusticum wallichii, 1-3 g of schisandra chinensis, 3-5 g of rhizoma polygonati, 2-5 g of radix ophiopogonis, 100-200 mg of algal oil, 200-300 mg of taurine, 150-200 mg of grape seed extract, 3-5 ml of perilla seed oil, 50-80 ml of yoghourt, 30-50 ml of walnut juice and 30-50 ml of peanut liquid. The selenium-enriched beverage is prepared from 30 to 50 milliliters of sweet almond liquid, 30 to 50 milliliters of black sesame liquid, 30 to 50 milliliters of mango juice, 50 to 100 milliliters of apple juice, 30 to 50 milliliters of tomato juice, 50 to 80 micrograms of selenium-enriched yeast, 25 to 50 milligrams of vitamin C, 125 to 25 milligrams of vitamin E, 0 to 15 milligrams of vitamin B1 {thiamine}, 15 milligrams of vitamin B2 {riboflavin}, 0 to 15 milligrams of vitamin B2 {pyridoxine}, 15 milligrams of vitamin B6 {pyridoxine}, 25 milligrams of vitamin B9 {folic acid}, 40 micrograms of vitamin B9 {folic acid}, and 0 to 75 milligrams of vitamin B12 {cobalamin}. After being taken by various people for a period of time, the health-care food is smooth and delicious in taste and free of adverse reaction through evaluation in multiple aspects, and the health-care effect and feeling state of the health-care food are better than those of the prior art. And the health-care tea is suitable for a wide range of people, is beneficial to market promotion, and enables more people to achieve the health-care effect of preventing diseases before diseases.

The invention relates to an aneurinibacillus michaeli ZKSW002 as well as a fungicide and application thereof, and belongs to the technical field of microorganisms. The bacillus michaeli ZKSW002 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No.36075, the preservation date is September 25, 2025, and the address of the preservation institution is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing. The invention further provides application of the thiamine bacillus migulensis ZKSW002 in inhibition of harmful bacteria in soil, prevention and treatment of root-knot nematode and promotion of plant growth. The thiamine bacillus michaeli ZKSW002 disclosed by the invention not only can promote the growth of crops and realize weight loss and synergism, but also can control the occurrence of soil-borne fungal and bacterial diseases, and can inhibit the growth of root-knot nematode. Chemical pesticide application can be reduced, pesticide residues are reduced, and sustainable development of agricultural economy is promoted.

The invention relates to an elsholtzia and ginseng composite peptide special diet for improving cardiovascular and cerebrovascular diseases and microcirculation disturbance and a preparation method thereof. The special diet comprises the following components: 5-15% of small molecule peptide; 18-65% of a plant extract; 0.1 to 3 percent of gamma-aminobutyric acid; 0.01 to 1 percent of N-acetylneuraminic acid; 0.005% to 0.1% of thiamine; 0.001 to 0.05 percent of riboflavin; and the balance of auxiliary materials. Wherein the plant extract comprises at least one of elsholtzia, rhizoma zingiberis and ginseng. According to the scheme provided by the invention, the elasticity and permeability of blood capillaries can be improved, microcirculation can be improved, blood fat can be reduced, and cardiovascular and cerebrovascular diseases can be effectively prevented and relieved.

The invention discloses a novel intestinal probiotic butyric acid monad and application thereof, the novel intestinal probiotic butyric acid monad is preserved in Guangdong Microbiological Culture Collection Center, and the preservation number is GDMCC No.67648. A mouse model proves that the butyric acid monad can promote synthesis of intestinal TMP (Trimethoprim) by remodeling intestinal steady state, and then the TMP is converted into thiamine. Through intestinal liver circulation, thiamine accumulates in the liver and is further converted into TPP. The process promotes the degradation of BCAs, further regulates the lipid metabolism of the liver, and obviously alleviates the progress of metabolic dysfunction related fatty liver diseases induced by high fat diet.

The invention relates to the field of medicines, in particular to a construction method of an Alzheimer's disease non-human primate model. A small dose of thiamine antagonist pyrithiamine is given to the chronic abdominal cavity to induce chronic thiamine metabolic disorder, so that the non-human primate marmoset Alzheimer disease model capable of reflecting the Alzheimer disease course is established, and the method has the advantages of simplicity in operation, small animal injury and the like; therefore, the method is beneficial to further basic clinical transformation research and the like, and has more important scientific significance and economic value.

To provide an aqueous ink composition capable of maintaining stable quality over a long period of time.SOLUTION: The ink composition contains at least a coloring material, water, and thiamine, a thiamine derivative or a salt thereof.SELECTED DRAWING: None

The disclosed invention relates to a chemical composition that can be taken orally and supplements an unhealthy diet and lifestyle. In one aspect of the invention the chemical composition includes Retinol Palmitate, Thiamine, Riboflavin, Niacin, Nicotinamide mononucleotide (NMN), Pyridoxal, Folic Acid, Cyanocobalamin, Cholecalciferol, Zinc, Manganese, Copper, Calcium, Magnesium, Iron, L-Selenomethionine, Lysine, Phenylalanine, L-Threonine, L-Methionine, L-Histidine, L-Tryptophan, L-Leucine, L-Isoleucine, L-Valine, Cinnamon Bark Powder, and Curcumin.

A topical composition comprising a nanonised L-glutathione and cyclodextrin complex, together with ascorbic acid in a weight ratio of glutathione to ascorbic acid from 7:1 to 15:1 and from 1:1 to 1:15 and a further compound comprising dexpanthenol, thiamine, benzalkonium chloride, sodium hyaluronate or acetyl-L-cysteine, which composition is topically administered for treating the symptoms of viral infection including COVID-19 and influenza, and for treating herpes simplex, herpes zoster, post herpetic neuralgia, genital herpes, alcohol detoxification, high triglycerides, age or liver spots and lupus.

The invention discloses application of thiamine in improving the sugar utilization rate and growth performance of sturgeons, and belongs to the field of aquaculture. It is proved for the first time that by enhancing a glycolytic pathway, inhibiting a gluconeogenesis pathway and promoting glycogen decomposition, the thiamine effectively improves the sugar metabolism capacity of sturgeons and reduces hepatic glycogen deposition and fat accumulation, so that the risk of metabolic disorder is reduced. Meanwhile, thiamine also promotes muscle fiber growth, so that the growth speed of the sturgeons and the feed utilization rate are remarkably increased. Therefore, the thiamine can be used as a feed additive for preparing the feed for improving the sugar utilization rate and the growth performance of the sturgeons. A safe and efficient nutrition regulation and control scheme is provided for sturgeon culture, the feed utilization rate and culture benefits are improved, meanwhile, ecological risks such as antibiotic abuse are avoided, and remarkable economic benefits and application prospects are achieved.

The application discloses a strawberry tissue culture and rapid propagation method based on natural extracts and belongs to the technical field of strawberry tissue culture and rapid propagation. The application takes MS culture medium as a basis, uniformly adds sucrose as a carbon source in the culture medium, and uniformly adds ascorbic acid (VC) and thiamine (VB1) as coenzyme vitamins to provide a uniform nutrient environment, and takes eleutherococcus senticosus extract as a growth regulator to replace traditional 6-BA, so that the browning rate and the malformation rate of the strawberry tissue culture and rapid propagation can be effectively reduced, and the proliferation rate, the survival rate and the morphological performance are equivalent to those of conventional culture (6-BA is added in the culture medium). The application solves the problems of synthetic hormone dependence and residues in the prior art, reduces the malformation rate and the browning rate of the tissue culture seedlings, and has a good popularization and application prospect.

Provided is use of thiamine pyrophosphokinase TPK as a target in the treatment of Alzheimer's disease; and AD symptoms due to the inhibited TPK can be prevented by promoting the kinase activity and / or expression level of TPK protein in brain with TPK as a target.

The application provides a full-synthetic culture medium for 2-keto-gluconic acid producing bacteria proliferation and application thereof, and belongs to the technical field of microorganisms. The full-synthetic culture medium for 2-keto-gluconic acid producing bacteria proliferation culture comprises 10.0-40.0 g / L of glucose, 0.5-4.0 g / L of urea, 5.0-30.0 mg / L of thiamine, 0.5-3.0 mg / L of biotin, 1.0-4.0 g / L of NaH2PO4, 0.7-2.1 g / L of KH2PO4, 0.1-0.3 g / L of MgSO4·7H2O and 0.0-5.0 g of CaCO3. The full-synthetic culture medium or semi-synthetic culture medium is subjected to proliferation culture, and it is shown that the full-synthetic culture medium can completely replace the semi-synthetic culture medium, guarantees the repeatability of culture results, and further fermentation production of the bacteria strains subjected to the proliferation culture will not affect the stability of the fermentation production of the bacteria strains.

The invention provides a method of promoting weight management in a mammal comprising administering to the mammal a composition comprising at least one weight loss agent and at least one mitochondrial enhancer. The weight loss agent can be selected from the group consisting of psyllium, guar gum, capsaicin, chitosan, caffeine, gamboge, mume, capsaicin, yohimbine, butterfly pea, glucomannan, African mango, guarana, pyruvate, carnitine, beta-glucan, fucoxanthin, raspberry ketone, white kidney bean, kola nut, chromium, ginseng, psyllium, St. John's wort, dandelion, hydroxycitric acid, conjugated linoleic acid, green tea, black tea, coffee bean extract, forskolin, and bitter orange. The mitochondrial enhancer can be selected from the group consisting of beetroot extract, nitrate, idebenone, nicotinamide riboside, elamipretide, vitamin C, vitamin D, vitamin E, thiamine, riboflavin, magnesium, calcium, phosphate, phospholipid, creatine, pyruvate, coenzyme Q10, NADH, niacin, L-carnitine, dichloroacetate, curcumin, schisandrin, and resveratrol. Compositions for weight management are also provided.

The invention discloses a paraquat synthesis process and processing equipment thereof, and belongs to the technical field of paraquat synthesis. The paraquat synthesis process comprises a polymerization reaction and an oxidation reaction, and the polymerization reaction comprises the following steps: sequentially adding 1-methyl pyridine chloride and a catalyst A into a first high-pressure kettle, carrying out vacuumizing-nitrogen displacement on the high-pressure kettle for later use, adding a catalyst B into a second high-pressure kettle, and carrying out vacuumizing-nitrogen displacement for later use. According to the paraquat synthesis process and the paraquat processing equipment provided by the invention, a ternary concerted catalysis system of thiamine hydrochloride, caustic soda liquid and tetrabutylammonium salt is adopted, so that the conversion rate of 1-methyl pyridine chloride is stable; the addition of the liquid caustic soda improves the catalytic activity of thiamine hydrochloride and the catalytic efficiency of polymerization reaction, the yield of paraquat reaches 93% or above, the synergistic effect of the catalyst significantly shortens the oxidation time, and the efficiency is improved by 7-8 times compared with that of a single catalyst system.

The present invention relates to over the counter (OTC) film coated tablet compositions comprising one or more types of vitamins. Specifically, the invention focuses on formulations that include B vitamins, such as thiamine (B1), riboflavin (B2), nicotinamide (B3), pantothenic 5 acid (B5), pyridoxine (B6), biotin (B7), folic acid (B9), and cobalamin (B12). These vitamin- enriched tablets are intended for dietary supplementation to support various bodily functions, including energy metabolism, nervous system health, and the maintenance of healthy skin, hair, and eyes.