Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

48 results about "Sodium ascorbate" patented technology

Sodium ascorbate is one of a number of mineral salts of ascorbic acid (vitamin C). The molecular formula of this chemical compound is C₆H₇NaO₆. As the sodium salt of ascorbic acid, it is known as a mineral ascorbate. It has not been demonstrated to be more bioavailable than any other form of vitamin C supplement.

Method for detecting extracellular vesicle fusion by adopting fluorescence resonance energy transfer

PendingCN121476144AFluorescence/phosphorescenceSodium ascorbateGain
The invention provides a method for detecting fusion of extracellular vesicles by adopting fluorescence resonance energy transfer, and belongs to the technical field of extracellular vesicles. A dynamic fluorescence monitoring system is established, low-power laser excitation is adopted, dual-wavelength fluorescence signals are monitored at the same time, fluorescence signal data are collected, graded gain regulation and control processing is carried out through five threshold values, and a fluorescence signal super-sparse matrix is constructed; establishing a fluorescence signal processing matrix model, converting the super-sparse matrix into a dense matrix, constructing a gain matrix for signal correction, calculating a fluorescence resonance energy transfer efficiency parameter, obtaining a standardized efficiency value through matrix operation, outputting an extracellular vesicle fusion kinetic analysis result, and establishing a quantitative evaluation system. The technical problems of poor signal stability and low detection precision in the process of fluorescence resonance energy transfer detection of extracellular vesicle fusion are solved.
Owner:QINGDAO RAISECARE BIOTECHNOLOGY CO LTD

Novel air regulating agent and preparation process thereof

PendingCN121942757ARelease rate dynamic synchronizationdynamic sync release rateDispersed particle separationEdible seed preservationSodium ascorbateEthylic acid
The invention relates to the technical field of air conditioning agents, and discloses a novel air conditioning agent and a preparation process thereof, the novel air conditioning agent is prepared from the following raw materials by mass: 10.0-20.0% of light calcium carbonate; 25.0% to 32.5% of D-sodium erythorbate; 5.0%-15.0% of an odor absorbing agent; 0.5%-2.0% of ferrous acetate; 1.0%-3.0% of sodium carbonate; 0.5%-1.5% of citric acid; 15.0% to 20.0% of sodium-based montmorillonite; 5.0% to 10.0% of silicon dioxide; 1.5% to 4.5% of an anti-flocculation synergist; and the balance of water. The device realizes stable air pressure in a reaction period and low-temperature quick effect, effectively absorbs and removes peculiar smell, solves the hardening problem in water-containing material production, and is suitable for industrial continuous production.
Owner:BEIJING YINGFENG LITAI TECH TRADE +1

3n-PTD ligand, and preparation method and application thereof

The application belongs to the technical field of extraction separation, and particularly relates to a 3N-PTD ligand and a preparation method and application thereof. The preparation method provided by the application comprises the following steps: mixing 3-chloropropylamine hydrochloride, sodium azide and deionized water, and performing a reflux reaction to obtain 3-azidopropylamine; dissolving 2,6-diethynylpyridine, 3-azidopropylamine, sodium ascorbate and CuSO4.5H2O, and performing a click reaction to obtain the 3N-PTD ligand. The yield of the 3N-PTD ligand obtained by the preparation method is high.
Owner:LANZHOU UNIV

Whitening and brightening composition and cosmetic thereof

The invention discloses a whitening and brightening composition and a cosmetic thereof. The whitening and brightening composition is prepared from ascorbyl tetraisopalmitate, tranexamic acid, Brigtenyl, LightSKN CN, a resveratrol fermentation product, fermented lotus essence and super vitamin A, brigtenyl is a mixture composed of a first solvent, glycerin and diglucosyl gallic acid; lightSKN CN is a mixture composed of a second solvent, 1, 3-propylene glycol, xanthophyll, lecithin, sodium ascorbate and vitamin E; the resveratrol fermentation product is a mixture composed of a third solvent, a pichia pastoris fermentation lysate filtrate and resveratrol; the fermented lotus seed essence is a mixture composed of a fourth solvent, butanediol and a lotus seed extract; the super vitamin A is a mixture of isosorbide dimethyl ether and hydroxyl pinacolone retinoate. The whitening and brightening composition not only can inhibit melanin generation, reduce melanin transfer and accelerate melanin metabolism, but also can remove excessive free radicals in skin, so that the effects of long-acting skin whitening and skin brightening are achieved.
Owner:GUANGDONG BASONA BIOTECHNOLOGY CO LTD

Preparation method of silicon quantum dot-Fe < 3 + > fluorescent probe and application of silicon quantum dot-Fe < 3 + > fluorescent probe in detection of glyphosate pesticide residues

The invention discloses a preparation method of a silicon quantum dot-Fe < 3 + > fluorescent probe and application of the silicon quantum dot-Fe < 3 + > fluorescent probe in detection of glyphosate pesticide residues, belongs to the field of analytical chemistry, and solves the problems that an existing detection method is long in detection time consumption, complex in sample pretreatment and difficult in high-throughput analysis. The preparation method comprises the following steps: introducing a newly prepared sodium ascorbate solution and a 3-aminopropyltrimethoxysilane solution into ultrapure water for reaction; dialyzing the solution in distilled water to remove unreacted solvent, and storing the obtained solution in a dark place at room temperature; carrying out rotary evaporation on the solution until the solution is viscous, pumping by a vacuum pump until the solution is dry, and dissolving by distilled water to obtain a silicon quantum dot solution; and incubating the silicon quantum dot solution and Fe < 3 + > at room temperature to form the silicon quantum dot-Fe < 3 + > fluorescent probe. The preparation method is simple, and reaction products are easy to separate and purify; the method is simple and convenient in glyphosate detection operation, good in selectivity, rapid in response and high in sensitivity, and can be used for rapid and quantitative detection of glyphosate pesticide residues in vegetables.
Owner:LANZHOU INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES

Photocatalytic stereoselective E-type olefination of alkynyl amide and preparation method of alkynyl amide

PendingCN121974821Ashort reaction cyclefew reaction stepsOrganic compound preparationCarboxylic acid esters preparationSodium ascorbateActive agent
The invention discloses photocatalytic stereoselective E-type olefination of alkynyl amide and a preparation method of the alkynyl amide. The method is carried out in a water-phase micelle reaction system and is completed under the driving of visible light. According to the method, an alkynyl amide compound is taken as a raw material, sodium ascorbate is taken as a green reducing agent, Ru (bpy) 3 (PF6) 2 or [Ir (dtbpy) (ppy) 2] PF6 is taken as a photocatalyst in a water-phase micelle environment formed by a surfactant lauryl sodium sulfate (SDS), and under the protection of inert gas, catalytic circulation is initiated by visible light irradiation at 20-40 DEG C, so that the alkynyl amide compound is highly selectively converted into an E-type olefin product. The method is mild in condition, simple in step, high in stereoselectivity, environment-friendly and safe to operate, the problem that flammable and explosive reagents or harsh reaction conditions need to be used in a traditional method is solved, and a green and efficient preparation way is provided for preparation of the E-type acrylamide compound.
Owner:SHAANXI UNIV OF SCI & TECH

Method for extracting tellurium from sodium tellurite solution through electrodeposition

The invention discloses a method for extracting tellurium from a sodium tellurite solution through electrodeposition, and belongs to the technical field of non-ferrous metal hydrometallurgy. The method comprises the following steps: dissolving crude tellurium dioxide in a sodium hydroxide solution at 60-90 DEG C to prepare a sodium tellurite electrolyte containing 200-240 g / L of tellurium and 90-110 g / L of sodium hydroxide; in the electrodeposition process, a composite additive composed of sodium ascorbate, pentasodium diethylenetriamine pentaacetate, sodium citrate and polyvinylpyrrolidone is synchronously added into the electrolyte. And carrying out electrodeposition for 14-15 days under the conditions that the current density is 40-60A / m, the voltage is 15-30V and the temperature is 15-30 DEG C. Through the synergistic effect of the composite additive, tellurite radicals in the anode region are remarkably inhibited from being oxidized into insoluble sodium tellurate, heavy metal impurity ions in the electrolyte are strongly complexed, and therefore the direct recovery rate of tellurium is increased to 90% or above while the better current efficiency is kept, and the purity of the obtained tellurium ingot reaches 99.95% or above.
Owner:SHANDONG HUMON SMELTING

An antioxidant jam and a method for preparing the same

PendingCN122123479AFood shapingSodium ascorbateMicrobiology
This invention belongs to the field of food processing technology and provides an antioxidant jam and its preparation method. The invention employs a synergistic design of a pectin-calcium ion microgel and a core-shell microcapsule bilayer microstructure. The core of the core-shell microcapsule contains ascorbic acid or sodium ascorbate, while the shell contains a pectin-calcium ion crosslinking network. This design helps to balance processing adaptability, structural stability, and preservation of antioxidant activity. It solves the technical challenges of the coupling contradiction between gel strength and water-free properties after the introduction of the ion-crosslinked microstructure, the synergistic optimization of microcapsule encapsulation efficiency and controllable release, and the thermosensitive degradation of ascorbic acid under heat treatment and shear conditions. This invention has broad application value in functional food fields such as jams, jellies, and baking fillings.
Owner:SHANDONG JOYWIN GREEN AGRI DEV CO LTD

Fluorescence-based multicycle nucleic acid sequencing reaction using imaging reagents, kits

The present application relates to the technical field of gene sequencing, in particular to an imaging reagent and a kit for a multi-cycle nucleic acid sequencing reaction based on fluorescence. In the imaging reagent, the synergistic effect of the combination of ethyl 3,4-dihydroxybenzoate, 4-hydroxy-3-methoxyacetophenone and sodium ascorbate reduces the generation of free radicals, inhibits nucleic acid damage during the imaging process, reduces phasing and pre-phasing, and ultimately improves the accuracy of long read sequencing. In order to improve the sequencing read length, three functional components, namely antioxidants, fluorescence quenching inhibitors and free radical scavengers, are added to the traditional imaging reagent. Compared with the existing imaging protectants, the present application creatively selects three antioxidants, namely ethyl 3,4-dihydroxybenzoate, 4-hydroxy 3-methoxy acetophenone and sodium ascorbate, for compounding, so as to exert a synergistic effect and eliminate the need for adding fluorescence quenching inhibitors and free radical scavengers.
Owner:SIKUN LIFE SCIENCE CO LTD

Zero-lactose formula goat milk powder for pets and preparation method of zero-lactose formula goat milk powder

The invention discloses zero-lactose formula goat milk powder for pets and a preparation method of the zero-lactose formula goat milk powder, and relates to the technical field of preparation of goat milk powder. Comprising the following raw materials: raw goat milk, lactase L3000, sodium citrate, low-sensitivity whey protein, medium-chain triglyceride, fructo-oligosaccharide, galactooligosaccharide, modified sodium caseinate, modified chicken flavor peptide, composite minerals, composite vitamins, trehalose, sodium ascorbate, microcrystalline cellulose and polyglycerol fatty acid ester. According to the invention, the modified chicken flavor peptide is added, the chitosan oligosaccharide and gamma-aminobutyric acid modified chicken flavor peptide in the modified chicken flavor peptide realize long-acting retention of natural chicken flavor by virtue of a double-layer coating structure, the flavor is prevented from being oxidized and losing aroma during processing and storage, and the ingestion willingness of pets is remarkably improved; the chitosan oligosaccharide can adjust the balance of intestinal flora of the pet, and the gamma-aminobutyric acid can relieve the stress reaction of the pet during ingestion, so that the feed additive is suitable for weaned or food-changing pets, and achieves triple effects of aroma enhancement, intestine protection and relieving.
Owner:SHANXI YOULISHI DAIRY CO LTD

Hydrogel for sweat glucose detection, preparation method of hydrogel and spontaneous sweating type hydrogel sweat glucose detection sensor

The invention discloses hydrogel for sweat glucose detection, a preparation method of the hydrogel and a spontaneous perspiration type hydrogel sweat glucose detection sensor, and relates to the field of biological fluid characteristic object recognition, and the preparation method of the hydrogel comprises the steps that firstly, phytic acid and aniline monomers serve as raw materials, and phytic acid doped polyaniline powder is prepared; mixing Mxene, methylene blue, sodium ascorbate, the phytic acid doped polyaniline powder, acrylamide and N, N '-methylene bisacrylamide in deionized water to obtain a mixed solution; dropwise adding an ammonium persulfate solution into the mixed solution, stirring and standing to obtain a hydrogel intermediate; and finally, sequentially activating and modifying the hydrogel intermediate, and dispensing glucose oxidase to obtain the hydrogel for sweat glucose detection. The hydrogel prepared by the invention has high ion / electron conductivity, enzyme immobilization ability and mechanical flexibility. The interface charge transfer efficiency can be improved and multifunctional integration can be realized by integrally designing the electrode and a carbon electrode into a sensor of an interdigital structure.
Owner:HENAN UNIVERSITY OF TECHNOLOGY

Lactobacillus salivarius preparation and application thereof in regulating vaginal environment

PendingCN121466144AAntimycoticsUnknown materialsBiotechnologyLactobacillus salivarius
The invention relates to the technical field of microbial preparations, and discloses a lactobacillus salivarius preparation, which comprises a core material and a wall material, the core material comprises a lactobacillus salivarius suspension and a protective agent solution, and the wall material is 1-3% by mass of a sodium alginate aqueous solution or 5-10% by mass of a whey protein aqueous solution. The protective agent solution comprises the following components in percentage by mass: 5-8% of glycerol, 10-15% of skim milk powder, 0.3-0.8% of sodium ascorbate and 6-10% of trehalose. By systematically screening and optimizing the components and proportion of the protective agent, an efficient protective system is constructed, the survival rate of thalli in the freeze-drying process and the stability of the preparation in long-term storage are remarkably improved, the preparation can quickly recover and maintain the healthy acidic environment of vagina, and the preparation has a good application prospect. Breeding of various common harmful bacteria is remarkably inhibited, and the specific effects of adjusting vagina micro-ecological balance and preventing and assisting in treating related gynecological inflammation are achieved.
Owner:SHANGHAI MEIHA BIOTECHNOLOGY DEV CO LTD

A method for manufacturing a solid oxygen-removing, bactericidal, corrosion-inhibiting, and scale-inhibiting agent for seawater oil well pipelines

ActiveCN120664708BSeawater treatmentSpecific water treatment objectivesMeth-Aminophenylboronic acid
This invention relates to the field of anti-corrosion reagent technology, specifically disclosing a method for manufacturing a solid oxygen-removing, bactericidal, corrosion-inhibiting, and scale-inhibiting agent for seawater oil well pipelines. The agent comprises a three-layer core-shell structure: the core layer is composed of a copolymer hydrogel of 2-acrylamido-2-methylpropanesulfonic acid and N-vinylcaprolactam, loaded with sodium isoascorbate and a copper-L-histidine complex; the middle layer is composed of 3-aminophenylboronic acid-functionalized silica nanoparticles and catechol linked by dynamic borate ester bonds; and the shell layer is composed of a copolymer of 3,4-dihydroxyphenylalanine and 1H,1H,2H,2H-perfluorodecyl acrylate coating a corrosion-inhibiting and bactericidal complex. This invention overcomes the pH conflict between oxygen removers and corrosion inhibitors in traditional reagents through the synergistic effect of the core-shell structure and dynamic bonds, achieving integrated functions of oxygen removal, bactericidal action, corrosion inhibition, and scale inhibition. It effectively inhibits microbial corrosion, reduces the risk of scaling, extends the lifespan of seawater pipelines, and is suitable for complex marine conditions.
Owner:SHANDONG JICHANG ENVIRONMENTAL ENG CO LTD

Hairpin type DNA-copper cluster probe for rapid ratio fluorescence detection of Hg < 2 + > and preparation method of hairpin type DNA-copper cluster probe

PendingCN121825530AMaterial nanotechnologyNanoopticsSodium ascorbateMorpholine
The invention discloses a hairpin type DNA-copper cluster probe for rapid ratio fluorescence detection of Hg < 2 + > and a preparation method, the hairpin type DNA-copper cluster probe contains a hairpin type DNA template (hpDNA) capable of emitting strong red fluorescence and weak blue fluorescence at the same time, and the sequence of the hairpin type DNA template is 5 '-TTTTTTTTTTTTTTTTTTTTT TTTTCGCGCGATATATCGCGCG-3'. The method comprises the following steps: preparing a single-stranded DNA aqueous solution by using a 3-morpholine propanesulfonic acid buffer solution, heating the single-stranded DNA aqueous solution in a constant-temperature water bath kettle, cooling to room temperature, and refrigerating and storing in a refrigerator to form an hpDNA template solution; adding a copper sulfate solution into the hpDNA template solution, and incubating at constant temperature to obtain a mixed solution; and adding a sodium ascorbate (SA) solution into the mixed solution, reacting at a constant temperature, and reducing Cu < 2 + > coordinated on the hpDNA template by sodium ascorbate to obtain the hairpin type DNA-copper cluster probe for rapid ratio fluorescence detection of Hg < 2 + >. The hairpin DNA-copper cluster (hpDNA-CuNCs) probe can be used for rapid ratio fluorescence detection of Hg < 2 + >. The hpDNA-CuNCs probe has excellent selectivity on Hg < 2 + >, is used for rapid and sensitive detection of trace Hg < 2 + > in an actual water body sample, and has an accurate detection result.
Owner:SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING

Cranberry honey ice cream and preparation method thereof

PendingCN121621430AFrozen sweetsBiotechnologyIcing sugar
The invention provides cranberry honey ice cream and a preparation method thereof, and the cranberry honey ice cream is prepared from the following raw materials based on 100 jin of finished products: 8 jin of powdered sugar, 2.5 jin of non-dairy creamer, 12 jin of honey, 65 g of a stabilizer, 15 g of a composite additive, 3 g of ethyl maltol, 3.5 g of vanillin, 15 g of molasses element, 80 jin of water, 50 g of essence, a proper amount of carmine, 3 jin of cranberry freeze-dried powder, 5 jin of natural cranberry juice and 2 g of sodium ascorbate. The stabilizer is formed by compounding xanthan gum and guar gum according to the mass ratio of 2: 1; the composite additive is prepared by compounding monoglyceride and polyglycerol fatty acid ester according to a mass ratio of 3: 1; the Changbai mountain linden honey, the cranberry freeze-dried powder and the natural cranberry juice are fused and matched with the high-purity sodium ascorbate, so that the nutritional structure is enriched, and functional components such as honey active enzyme and cranberry anthocyanin are effectively reserved; a compounding system of xanthan gum and guar gum and a compounding system of monoglyceride and polyglycerol fatty acid ester are adopted, so that the stability of a raw material system is remarkably improved.
Owner:HEILONGJIANG WANGMISHIJIA AGRICULTURAL ECOLOGICAL DEVELOPMENT CO LTD

Rose essential oil microencapsulated composition for improving sleep as well as preparation method and application of rose essential oil microencapsulated composition

The invention discloses a rose essential oil microencapsulated composition for improving sleep as well as a preparation method and application of the rose essential oil microencapsulated composition, and belongs to the technical field of pharmaceutical preparations. The composition is prepared from the following components in parts by weight: 10 to 15 parts of rose essential oil, 2 to 6 parts of peony seed oil, 12 to 20 parts of octenyl succinic acid dextrin, 1 to 5 parts of freshly squeezed olive oil, 0.3 to 1 part of acer truncatum seed oil, 8 to 15 parts of beta-cyclodextrine, 1 to 5 parts of sodium ascorbate, 0.5 to 1 part of sleep-aiding raw materials, 5 to 15 parts of Arabic gum and 100 to 150 parts of water. Compared with the prior art, the problems that the rose essential oil is easy to volatilize and unstable and the bioavailability of various active ingredients is low are effectively solved, targeted efficient release of the active ingredients in the intestinal tract is achieved, the sleep improving effect is remarkably improved, the product safety is high, and the rose essential oil can be applied to preparation of drugs for improving sleep.
Owner:YUNXIN HUIJU TECHNOLOGY DEVELOPMENT (CHENGDU) CO LTD

Refining method of sodium ascorbate

PendingCN121873018AOrganic chemistryPharmacy medicineSodium ascorbate
The invention relates to the technical field of medicine preparation, in particular to a method for refining sodium ascorbate. The crude sodium ascorbate prepared by gulonic acid ester conversion is used as a raw material, and the high-purity sodium ascorbate finished product is prepared through two times of crystallization refining, so that refining steps of ion exchange, concentration and the like of the raw material vitamin C, which are long in time consumption and high in energy consumption, are omitted, and the preparation period of the finished sodium ascorbate finished product is greatly shortened; a new thought is provided for preparation of a sodium ascorbate finished product.
Owner:CSPC WEISHENG PHARM (SHIJIAZHUANG) CO LTD

Foam type collagen biological material, product and preparation method

The invention provides a foam type collagen biological material, a product and a preparation method, and relates to the technical field of biological materials. The preparation method comprises the following steps: S1, adding raw materials into enzymatic hydrolysate for enzymolysis, centrifuging, and taking supernatant, so as to obtain crude collagen extract; s2, carrying out ultrafiltration purification treatment on the collagen crude extract, then carrying out high-pressure homogenization, and centrifuging to obtain a collagen stock solution; s3, adding a protective agent into the collagen stock solution, homogenizing, transferring into a stainless steel bottle, and storing in a carbon dioxide atmosphere of 2 atmospheric pressure to obtain a foam type collagen biological material; the protective agent in the step S3 is selected from at least two of sodium ascorbate, sodium citrate, hydroxyproline and polyvinylpyrrolidone; the volume ratio of the collagen stock solution to the protective agent in the step S3 is 1: (0.01-0.1). The biomaterial prepared by the invention is remarkably improved in anti-seepage performance, suture strength and mechanical property, and has outstanding clinical application value.
Owner:杭州倍朗生物科技有限公司

Red heme iron red ginseng and colla corii asini nutritional milk powder and preparation method thereof

The invention discloses ruddy heme iron red ginseng and donkey-hide gelatin nutritional milk powder and a preparation method thereof, and belongs to the technical field of milk powder, the ruddy heme iron red ginseng and donkey-hide gelatin nutritional milk powder comprises the following components in parts by mass: a wet process part: 420-455 parts of whole milk powder, 306-345 parts of dried skim milk, 185-205 parts of isomaltooligosaccharide (type 50) powder, 35-40 parts of polydextrose, 11.5-14.5 parts of a milk powder nutrition enhancer III, 0.3-0.5 part of compound L-carnitine, and 0.1-0.3 part of heme chloride; according to the ruddy heme iron red ginseng and donkey-hide gelatin nutritional milk powder and the preparation method thereof, the heme chloride is adopted as an iron source, the bioavailability of the red heme iron red ginseng and donkey-hide gelatin nutritional milk powder is remarkably higher than that of ferrous sulfate used in traditional iron-supplementing milk powder, meanwhile, through beta-cyclodextrin embedding treatment, the fishy smell problem of an iron agent is solved, gastrointestinal tract stimulation is avoided, and L-sodium ascorbate is matched, so that the nutrition of the milk powder is improved. And the iron absorption rate can be further improved.
Owner:DAQING GREEN LEAF DAIRY PROD CO LTD

A polypeptide self-assembled hydrogel and a preparation method and application thereof

The application discloses a kind of polypeptide self-assembly hydrogel and its preparation method and application.The application is obtained by dissolving sodium ascorbate in 0.1M phosphate buffer solution to obtain sodium ascorbate solution;Antibacterial peptide Jelleine-1 is dissolved in DMSO to be configured into 100mg / mL polypeptide stock solution;Sodium ascorbate solution is added to polypeptide stock solution, fully stirred and mixed, and placed into shape, to obtain polypeptide self-assembly hydrogel.The preparation method of the application is simple, the gelation speed is fast, the production cost is low, the obtained polypeptide self-assembly hydrogel has excellent antibacterial performance and antioxidant performance, and almost has no cytotoxicity and hemolytic toxicity, has good biocompatibility, can effectively inhibit bacterial infection in atopic dermatitis, reduce oxidative stress, thereby significantly relieving dermatitis symptoms.
Owner:LANZHOU UNIV

An antioxidant anti-aging pn complex and a method for preparing the same

PendingCN122163468ACosmetic preparationsToilet preparationsPhosphateSodium ascorbate
This invention belongs to the field of biopharmaceutical manufacturing technology and discloses an antioxidant and anti-aging PN complex and its preparation method, comprising: polydeoxyribonucleotide, epigallocatechin gallate, divalent magnesium ions, sodium ascorbate phosphate, citrate-sodium citrate buffer system, and water; the divalent magnesium ions form chelates with the phosphate groups on the polydeoxyribonucleotide molecular chain and the phenolic hydroxyl groups of epigallocatechin gallate, respectively, so that epigallocatechin gallate forms a continuously distributed molecular coating layer on the surface of the polydeoxyribonucleotide molecular chain; this invention solves the problem of heterogeneous gel aggregation caused by excessively fast reaction kinetics in the preparation of biopharmaceutical macromolecules by transforming the unavoidable disordered crosslinking between chains in conventional mixing processes into highly ordered intramolecular homogeneous encapsulation.
Owner:SUZHOU RUIOUMAN BIOTECHNOLOGY CO LTD

Liquid deodorant suitable for long-term storage and preparation method and application thereof

The invention discloses a liquid deodorant suitable for long-term storage and a preparation method and application thereof, and belongs to the technical field of microorganisms. The deodorant is composed of a stabilizing solution and an activating solution which are independently packaged. The stabilizing solution is prepared from composite bacillus, trehalose, D-alanine and sodium ascorbate; the activation liquid comprises lactic acid bacteria, L-alanine and an enzyme preparation. According to the invention, D-alanine is used for inhibiting spore germination and is matched with trehalose for synergistic protection; when in use, L-alanine and an enzyme preparation are used for breaking dormancy. The deodorant solves the problems of poor storage stability and slow activation of a liquid microbial inoculum, the spore retention rate exceeds 90% after the liquid microbial inoculum is stored at room temperature for 12 months, and the deodorant has an excellent rapid ammonia nitrogen removal effect.
Owner:XINJIANG HERUN TECH CO LTD

Nanometer ultramicro liquid DHA composition and preparation method thereof

The invention discloses a nano ultramicro liquid DHA composition and a preparation method thereof, and belongs to the technical field of functional foods. The composition is prepared from the following raw materials: DHA algae oil, phosphatidylserine, walnut peptide, cerebroprotein peptide, curcumin, piperine, a herba cistanche extract, a hericium erinaceus extract, vitamin B6, vitamin B12, magnesium citrate, maltitol liquid, concentrated apple clear juice, yellow lemon concentrated liquid, green lemon concentrated juice, sodium citrate, edible essence, polyglycerol fatty acid ester and soybean powder phospholipid. Sodium ascorbate, glycerol and water; the preparation method comprises the following steps: (1) weighing raw materials; (2) premixing the component 1; (3) premixing a component 2; (4) pre-dissolving the component 3; (5) preparing a coarse emulsion; (6) performing superfine emulsification; (7) blending and mixing; (8) homogenizing and emulsifying; (9) filling and sealing; and (10) sterilizing. The composition is suitable for heart and intelligence nutrition supplement of children and special crowds, and has good taste, physical stability and oral absorption performance.
Owner:BRAVEIY BIOTECHNOLOGY (ANHUI) CO LTD

Fresh-cut cistanche preservation method using plasma activated water in cooperation with composite color fixative

The invention discloses a fresh-cut cistanche preservation method by using plasma activated water in cooperation with a composite color fixative, and belongs to the technical field of preservation of traditional Chinese medicinal materials. The preservative comprises the following components: phytic acid, sodium erythorbate, sodium pyrosulfite and plasma activated water. The dosage ratio of the phytic acid to the sodium erythorbate to the sodium pyrosulfite to the plasma activated water is (1-5g): (4-10g): (1-5g): 1L. The preservative can obviously delay the browning process of the fresh-cut cistanche, effectively promote accumulation of Vc, total phenols and flavonoid active substances, enhance the activity of superoxide dismutase (SOD) and catalase (CAT) and inhibit the activity of polyphenol oxidase (PPO) and peroxidase (POD), thereby improving the fresh-cut quality of the cistanche.
Owner:XINJIANG ACADEMY OF FORESTRY SCI +1

Fluorescence detection method for cellulose paper-based sulfur-containing substances and application of fluorescence detection method

The invention discloses a fluorescence detection method of a cellulose paper-based sulfur-containing substance and application. A preparation method of a fluorescence probe comprises the following steps: carrying out chemical modification on cellulose twice to obtain modified cellulose; synthesizing a deep red solid product compound 1; and synthesizing a blue-green compound 2. Reacting the modified cellulose with a compound 1 in DMSO (Dimethylsulfoxide) at 100 DEG C for 6 hours; then adding a compound 2 and an aqueous solution in which sodium ascorbate and CuSO4. 5H2O are dissolved; and after freeze drying, washing with ethanol until effluent is colorless, and drying to obtain the red purple cellulose-based fluorescent probe. According to the present invention, the natural polymer cellulose is adopted as the substrate, and the two fluorophores are grafted to construct the near-infrared region ratio type fluorescence sensing platform, such that the cysteine (Cys) and the glutathione (GSH) can be highly selectively distinguished and detected, and the important application value is provided in the fields of biosensing, in vivo imaging and the like.
Owner:QILU UNIVERSITY OF TECHNOLOGY (SHANDONG ACADEMY OF SCIENCES)

A natural nano-selenium optimized combination method for inhibiting proliferation of cancer cells, inducing apoptosis of cancer cells and repairing damaged body tissue cells

PendingCN122074649AOrganic active ingredientsCapsule deliveryMethylselenocysteineVitamin C
This invention discloses a natural nano-selenium optimized composition, belonging to the technical field of functional foods and bioactive preparations. The composition uses sodium L-ascorbate, selenium-enriched yeast, L-ascorbic acid, D-biotin, and L-selenomethylselenocysteine ​​as core raw materials, compounded with edible corn starch, maltodextrin, magnesium stearate, and hydroxypropyl starch in empty capsules; each capsule contains 100 μg selenium, 100 μg biotin, and 100 mg vitamin C. This invention, through the synergistic effect of multiple selenium forms with vitamins and biotin, forms a stable natural nano-selenium system, selectively inhibiting cancer cell proliferation and inducing cancer cell apoptosis, while simultaneously repairing damaged body tissues and cells. It exhibits high bioavailability and good safety, making it suitable for adjuvant tumor treatment and body damage repair.
Owner:SHANDONG YUPIN TIANDAN MARINE BIOTECHNOLOGY CO LTD

Color protection composition and color protection method for preparing quick-frozen dandelion dish

PendingCN121667271AFruits/vegetable preservation by blanchingTaraxacum officinale leafIce water
The invention relates to the field of food processing color protection, in particular to a color protection composition and a color protection method for preparing quick-frozen dandelion dishes, the composition comprises sodium ascorbate, calcium lactate and EDTA-2Na, dandelions are washed, then placed in blanching liquid containing the color protection composition to be blanched, quickly fished out after blanching is finished, and subjected to shock cooling with ice water to 10 DEG C or below, and a finished product is obtained. Draining off water, immediately quickly freezing, and freezing and preserving in a refrigerator at the temperature of-18 DEG C; according to the compound color protection formula provided by the invention, the safety risk of heavy metals is avoided, enzymatic browning can be inhibited, and the color of dandelion is stable; the blanching temperature and time parameters matched with the characteristics of the dandelion leaves are optimized, the problems of high-temperature long-time softening and rotting and low-temperature short-time enzyme inactivation are solved, and chlorophyll degradation and nutrition loss are reduced while the activities of polyphenol oxidase and peroxidase are ensured to be rapidly passivated; the synergistic effect of composite color protection and blanching processes is achieved, the process is simplified, and the method is suitable for large-scale production of quick-frozen vegetables.
Owner:HEBEI UNIV OF ENG

Small-molecule protein environment air disinfecting and deodorizing preparation and application thereof

ActiveCN121797080BBiocideGas treatmentActive agentSodium ascorbate
The present application relates to the technical field of environmental purification and odor removal, and discloses a small-molecule protein environmental air disinfection and odor removal preparation and application thereof.The preparation is made of core protein components, sodium citrate, sorbitol, an anti-browning agent, L-sodium ascorbate, riboflavin, cyclodextrin or cyclodextrin derivatives, a surfactant, a preservative and deionized water, wherein the core protein components are enzymatic products with a molecular weight less than or equal to 20 kDa, and the preparation is prepared by establishing an anti-browning buffer environment, dissolving functional components, slowly adding the core protein components to make them disperse and dissolve, and finally adjusting the pH value and setting the volume.The core protein components with a molecular weight less than or equal to 20 kDa have more active sites, and can enhance the capture and combination capacity with indoor air chemical pollutants, and can act on bacterial cell structures or virus activity, so as to realize the multifunctional air purification effect of pollutant removal and biological disinfection and inactivation.
Owner:ZHEJIANG FUSKAI BIOTECHNOLOGY CO LTD

A bovine protein peptide composition for anti-skin aging and its preparation method

ActiveCN121648001BArginineSodium phosphates
This invention belongs to the field of skincare technology and provides an anti-aging bovine protein peptide composition and its preparation method. Bovine protein peptides with a molecular weight of 300-800 Da are prepared using sequential enzymatic hydrolysis. Active peptides with arginine and lysine content ≥18% are directionally enriched by cation exchange chromatography. These peptides are then combined with sodium ascorbate phosphate, tocopheryl acetate, and phytic acid to construct an antioxidant synergistic network. A biomimetic liposome carrier is prepared using phosphatidylcholine, cholesterol, and ceramide 3. A multilayer responsive coating design is employed, sequentially coating the carrier surface with a poly-L-histidine layer, a hyaluronic acid layer, and a polycaprolactone outer layer, and grafting hyaluronic acid oligosaccharides to form a stable multilayer structure. The prepared composition has an average particle size of 120-280 nm, a drug loading efficiency ≥82%, and a 24-hour cumulative release rate of 58-82%, exhibiting excellent controlled-release performance and anti-aging activity, making it suitable for the development and application of high-end anti-aging skincare products.
Owner:SHANDONG LONGBEI BIOTECHNOLOGY CO LTD

Lactobacillus plantarum microbial preparation as well as preparation method and application thereof

The invention relates to the technical field of microbial preparations, and discloses a lactobacillus plantarum microbial preparation as well as a preparation method and application thereof, and the lactobacillus plantarum microbial preparation is prepared by mixing lactobacillus plantarum wet bacterial sludge and composite protective matrix liquid and then performing vacuum freeze drying. The composite protection matrix liquid comprises trehalose, soluble soybean polysaccharide, L-sodium ascorbate, calcium lactate pentahydrate and sodium citrate dihydrate. The preparation method comprises the following steps: adding anhydrous betaine into fermentation liquor in the later period of fermentation, carrying out programmed cooling, and collecting bacterial sludge; mixing and redissolving the bacterial sludge and the matrix liquid, and then carrying out nitrogen shearing gas stripping; and then freeze-drying through a procedure including annealing treatment to obtain a finished product. According to the invention, through cooperation of wrapping of the polysaccharide-calcium microgel network and compatible solute regulation of intracellular accumulated betaine, ice crystal nucleation and dehydration shrinkage damage in the freeze-drying process are relieved, the survival rate of freeze-drying viable bacteria of the microbial preparation is improved, and the storage stability of the microbial preparation in subsequent probiotic food application is improved.
Owner:LESHAN HENGFENG HUABANG BIOTECHNOLOGY CO LTD