99 results about "Sodium ascorbate" patented technology

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses a synthetic nicotine composition and a preparation method thereof. The nicotine buccal film agent disclosed by the invention is prepared from the following components in parts by weight: 2 to 4 parts of nicotine clathrate compound powder, 0.2 to 0.6 part of phosphatidic acid, 0.1 to 0.3 part of tannic acid, 0.1 to 0.2 part of sodium ascorbate, 0.04 to 0.06 part of tocopherol, 0.01 to 0.02 part of ethylene diamine tetraacetic acid, 2 to 4 parts of povidone and 40 to 80 parts of absolute ethyl alcohol. The synthesized nicotine composition prepared by the invention can effectively relieve the phenomenon that the faster the nicotine is released, the stronger the bitter taste is. Meanwhile, in a high-temperature and high-humidity environment, the stability of nicotine can be effectively maintained, and the oxidation half-life period of nicotine is prolonged.

The invention belongs to the technical field of food and medicine, and relates to application of corn germ concentrated powder in improvement of osteoarthritis. The invention particularly relates to application of corn germ concentrated powder, namely corn antioxidant multienzyme, in preparation of medicines or health-care foods for treating rheumatoid arthritis and osteoporosis. In the corn germ concentrated powder, superoxide dismutase / (U / g) is greater than or equal to 8500, glutathione peroxidase / (U / g) is greater than or equal to 5000, and catalase / (U / g) is greater than or equal to 750. The corn germ concentrated powder can also be prepared by the following method: cleaning corn, germinating, adding water into the germinated corn, grinding and pulping, adding a settling agent into the corn steep liquor, standing, taking supernate, adding part of sodium ascorbate, performing temperature-controlled concentration, adding the rest sodium ascorbate and a stabilizer into the concentrated solution, and uniformly mixing to obtain the corn germ concentrated powder. And drying at controlled temperature, crushing, and mixing with a proper amount of silicon dioxide. The prepared corn germ concentrated powder has the effect of resisting rheumatoid arthritis.

The present disclosure provides a high-energy, low toxicity radiopharmaceutical composition comprising actinium that performs as an anti-tumor agent for targeted radionuclide therapy and has improved shelf-life stability. Specifically, the radiopharmaceutical composition may include 225Ac-PSMA I&T, sodium ascorbate, and optionally hydrochloric acid. The radiopharmaceutical composition may be suitable for administration to a patient in need thereof, such as for the purpose of treating prostate cancer.

The invention belongs to the technical field of seasoning processing, and particularly discloses salad dressing capable of improving the stability of natural pigments and a preparation method of the salad dressing. The salad dressing capable of improving the stability of the natural pigment comprises the following raw materials: high fructose corn syrup, yolk liquid, white granulated sugar, potassium sorbate, lemon concentrated juice, table vinegar, water, glycerol, the natural pigment, titanium dioxide, sucrose fatty acid ester, edible salt, xanthan gum, soybean oil, acetylated distarch adipate, sodium ascorbate, mustard powder and a rosemary extract. The HLB (Hydrophile Lipophile Balance) value of the sucrose fatty acid ester is The synergistic effect of all the components is remarkable, multiple defense lines of oxidation resistance, system stability, corrosion prevention and the like are constructed, and the probability of natural pigment fading in the salad dressing storage process is reduced.

The invention relates to the technical field of preparation of health-care products, in particular to a fat-soluble component nano-emulsion and a preparation method thereof. The preparation method comprises the following steps: stirring and dissolving the antioxidant and the caprylic / capric triglyceride, adding the vitamin D3 and the retinyl palmitate, and stirring and dissolving to obtain an oil phase; stirring the starch sodium octenylsuccinate in purified water until the starch sodium octenylsuccinate is dissolved, adding glycerol, and uniformly stirring and mixing to obtain a water phase; adding a small amount of water phase into the oil phase, and stirring at high speed to obtain primary emulsion; adding the primary emulsion into the residual water phase, stirring at a high speed, shearing and homogenizing to obtain a nano embedding emulsion; adding citric acid, cane sugar and sodium ascorbate into purified water, adding the nano embedding emulsion, and uniformly stirring to obtain a concentrated solution; and diluting the concentrated solution and adjusting the pH value to obtain the fat-soluble component nano-emulsion. The fat-soluble component nano-emulsion provided by the invention has good safety; the product can be easily absorbed and utilized by a human body, and is convenient for people to quickly supplement vitamin A and vitamin D3 required by the body.

This invention belongs to the field of crop cultivation technology, specifically relating to a rice nano-flavor enhancer and its application in rice cultivation. The rice nano-flavor enhancer of this invention is prepared from raw materials such as sodium octenyl succinate starch, sodium ascorbate, and sodium selenite. The prepared octenyl succinate starch-nano-selenium has advantages such as small nanoparticle size and system stability. This flavor enhancer can not only significantly improve the overall aroma of fragrant rice, but also enhance the aroma of non-fragrant rice. Specifically, it can significantly increase the content of volatile aroma compounds such as 2-acetyl-1-pyrroline (2-AP) in fragrant rice grains, and significantly increase the content of volatile aroma compounds such as vanillin, benzaldehyde, and geranylacetone in non-fragrant rice grains. Unlike traditional rice flavor enhancers, the rice nano-flavor enhancer of this invention has better applicability and a wider range of applications, helping to meet the growing market demand for high-quality rice.

The invention provides a method for detecting fusion of extracellular vesicles by adopting fluorescence resonance energy transfer, and belongs to the technical field of extracellular vesicles. A dynamic fluorescence monitoring system is established, low-power laser excitation is adopted, dual-wavelength fluorescence signals are monitored at the same time, fluorescence signal data are collected, graded gain regulation and control processing is carried out through five threshold values, and a fluorescence signal super-sparse matrix is constructed; establishing a fluorescence signal processing matrix model, converting the super-sparse matrix into a dense matrix, constructing a gain matrix for signal correction, calculating a fluorescence resonance energy transfer efficiency parameter, obtaining a standardized efficiency value through matrix operation, outputting an extracellular vesicle fusion kinetic analysis result, and establishing a quantitative evaluation system. The technical problems of poor signal stability and low detection precision in the process of fluorescence resonance energy transfer detection of extracellular vesicle fusion are solved.

The invention relates to the technical field of thin-layer chromatography detection, and discloses a thin-layer chromatography separation method for amino polyether and a matrix in a fluorine-18 labeled radiopharmaceutical, and the adopted developing solvent is acetonitrile and ammonia water, and the volume ratio of the acetonitrile to the ammonia water is 90: 10-85: 15. According to the method, amino polyether and matrix components are separated by adopting a developing solvent with a specific volume ratio, and particularly, sodium ascorbate in the amino polyether and the matrix is separated.

The present disclosure provides a high-energy, low toxicity radiopharmaceutical composition comprising actinium that performs as an anti-tumor agent for targeted radionuclide therapy and has improved shelf-life stability. Specifically, the radiopharmaceutical composition may include 225Ac-PSMA I&T, sodium ascorbate, and optionally hydrochloric acid. The radiopharmaceutical composition may be suitable for administration to a patient in need thereof, such as for the purpose of treating prostate cancer.

The invention discloses a vacuum color protection method of preserved apples, which comprises the following steps: peeling apples, removing kernels, and cutting the apples into apple slices; soaking the apple slices in a composite color-protecting solution, performing vacuum-pumping treatment, and continuing soaking to obtain the preserved apples subjected to color-protecting treatment; the composite color protection liquid is composed of citric acid, sodium erythorbate, sodium chloride, calcium chloride and water, the concentration of the citric acid is 3-6%, the concentration of the sodium erythorbate is 0.3-0.5%, and the concentration of the sodium chloride is 0.3-0.5%. The color fixative disclosed by the invention is combined with a vacuum mode, so that a greater benefit effect is exerted, and the color protection effect is improved under the condition that the water activity is not influenced. The method is simple in process and convenient to operate, toxic and harmful chemicals are not added, and the method has wide application and popularization prospects.

The invention discloses a rifapentine isoniazide tablet and a preparation method thereof, the rifapentine isoniazide tablet is a core-coated tablet, and comprises an inner-layer tablet core containing rifapentine and an outer-layer tablet layer containing isoniazide; the inner-layer tablet core comprises rifapentine, edetate disodium, sodium ascorbate and lauryl sodium sulfate, the rifapentine accounts for 53-63% of the total mass of the inner-layer tablet core, and the rifapentine tablet further comprises a filler, a stabilizer, a disintegrating agent, an adhesive, a surfactant, a lubricant and a coating layer; the coating layer coats the inner-layer tablet core; the outer sheet layer comprises isoniazide, a filling agent, a disintegrating agent, an adhesive, a lubricant and an adhesive; and the mass of the isoniazide accounts for 75-95% of the total mass of the outer sheet layer. According to the rifapentine isoniazide tablet disclosed by the invention, the compliance of a patient is enhanced. And meanwhile, the potential safety hazard problem of impurity increase caused by incompatibility of rifapentine and isoniazide is solved.

The invention provides starch sodium octenylsuccinate-free, protein-free and lactose-free fat powder as well as a preparation method and application thereof, and belongs to the technical field of foods. The fat powder provided by the invention comprises 25%-60% of glucose syrup (in terms of solid matter), 1%-20% of maltodextrin, 20%-50% of edible plant blend oil, 0.01%-3% of mono-and diglycerol fatty acid ester, 0.01%-3% of citric acid fatty glyceride, 0.1%-1% of sodium ascorbate, 0.005%-0.02% of ascorbyl palmitate and 0.01%-1% of potassium hydroxide. The fat powder provided by the invention is free of starch sodium octenylsuccinate, protein and lactose, good in solubility, good in dispersity and high in sinking speed. After being dissolved, the emulsion is milky white, has no (or few) small oil droplet floating, no precipitate and no floating object, and after standing, the solution is not layered.

The invention relates to the technical field of air conditioning agents, and discloses a novel air conditioning agent and a preparation process thereof, the novel air conditioning agent is prepared from the following raw materials by mass: 10.0-20.0% of light calcium carbonate; 25.0% to 32.5% of D-sodium erythorbate; 5.0%-15.0% of an odor absorbing agent; 0.5%-2.0% of ferrous acetate; 1.0%-3.0% of sodium carbonate; 0.5%-1.5% of citric acid; 15.0% to 20.0% of sodium-based montmorillonite; 5.0% to 10.0% of silicon dioxide; 1.5% to 4.5% of an anti-flocculation synergist; and the balance of water. The device realizes stable air pressure in a reaction period and low-temperature quick effect, effectively absorbs and removes peculiar smell, solves the hardening problem in water-containing material production, and is suitable for industrial continuous production.

The application belongs to the technical field of extraction separation, and particularly relates to a 3N-PTD ligand and a preparation method and application thereof. The preparation method provided by the application comprises the following steps: mixing 3-chloropropylamine hydrochloride, sodium azide and deionized water, and performing a reflux reaction to obtain 3-azidopropylamine; dissolving 2,6-diethynylpyridine, 3-azidopropylamine, sodium ascorbate and CuSO4.5H2O, and performing a click reaction to obtain the 3N-PTD ligand. The yield of the 3N-PTD ligand obtained by the preparation method is high.

The invention relates to the technical field of food processing, and discloses a roasted pepper sauce and a preparation method thereof. The roasted chili sauce comprises the following raw material components: a chili main material, an auxiliary material, a seasoning, a natural pigment and an antioxidant, wherein the chili main materials comprise red chilies, green chilies and yellow chilies; the auxiliary materials comprise a scorch aroma excitation auxiliary material and a flavor balance auxiliary material; the seasonings comprise ginger, garlic, salt and zanthoxylum oil; the antioxidant is selected from at least one of rosemary extract, tea polyphenol and sodium ascorbate. The preparation method of the roasted chili sauce is simple and controllable, the preparation process is standardized, the chili main material is cut into sections, then the chili sections are subjected to far infrared heating treatment, and then other raw materials are mixed, so that harmful substances and residues of tar, carbon black and the like caused by local high temperature are avoided, and the prepared roasted chili sauce is rich in scorch aroma flavor, rich in taste and rich in flavor. The color, the taste and the quality stability are good, and industrial production and market popularization are facilitated.

The invention relates to the technical field of medicinal preparations, in particular to a process for preparing instant BCAA powder, which comprises the following steps: (1) pretreatment: crushing a BCAA mixture until the particle size is 12-18 [mu] m, the ratio of leucine to isoleucine to valine in the BCAA mixture is 2.2: 1: 0.8; (2) mixing: putting 55-65% by mass of a composite instant auxiliary material, 2-4% by mass of a compound emulsifier, 1-3% by mass of sodium ascorbate, 1-2% by mass of a flavoring agent and 0.5-1% by mass of silicon dioxide into a three-dimensional mixer, mixing for 10min at 150r / min, then adding 20-30% by mass of the pretreated BCAA powder, and continuously mixing for 15min to obtain the premix. By optimizing the whole process of pretreatment, mixing, granulation, drying and screening, multi-dimensional improvement of instant solubility, anti-caking property, activity retention, taste, production efficiency and use convenience is realized. Compared with the prior art, the process has the advantages that the BCAA powder which is quick to dissolve, less in caking, high in activity and good in taste can be produced, the production efficiency is high, the cost is low, and the use scene is wide.

The application provides a purification method of sodium D-erythorbate, which comprises the following steps: (1) adding dimethyl carbonate into a reaction kettle, adding a catalyst, and then adding 2-keto-D-gluconic acid, so as to obtain an esterification liquid through reaction; (2) adding an inorganic base into the esterification liquid obtained in the step (1) and reacting for 1-2 hours, so as to obtain a reaction liquid; (3) filtering the reaction liquid obtained in the step (2), so as to obtain a filtrate and a filter cake, and the filter cake is the catalyst; (4) heating and reducing-pressure distilling the filtrate obtained in the step (3), so as to obtain methanol, dimethyl carbonate and a remaining component which is a crude product of sodium D-erythorbate, respectively; and (5) purifying the crude product of sodium D-erythorbate obtained in the step (4), so as to obtain a pure product of sodium D-erythorbate with a purity of more than 99.8%. The method does not use concentrated sulfuric acid, is simple in process and convenient in operation, has high environmental friendliness of solvents used in the purification process, is high in product purity and can well solve the problems of the prior art.

The invention discloses a whitening and brightening composition and a cosmetic thereof. The whitening and brightening composition is prepared from ascorbyl tetraisopalmitate, tranexamic acid, Brigtenyl, LightSKN CN, a resveratrol fermentation product, fermented lotus essence and super vitamin A, brigtenyl is a mixture composed of a first solvent, glycerin and diglucosyl gallic acid; lightSKN CN is a mixture composed of a second solvent, 1, 3-propylene glycol, xanthophyll, lecithin, sodium ascorbate and vitamin E; the resveratrol fermentation product is a mixture composed of a third solvent, a pichia pastoris fermentation lysate filtrate and resveratrol; the fermented lotus seed essence is a mixture composed of a fourth solvent, butanediol and a lotus seed extract; the super vitamin A is a mixture of isosorbide dimethyl ether and hydroxyl pinacolone retinoate. The whitening and brightening composition not only can inhibit melanin generation, reduce melanin transfer and accelerate melanin metabolism, but also can remove excessive free radicals in skin, so that the effects of long-acting skin whitening and skin brightening are achieved.

The invention discloses a preparation method of a silicon quantum dot-Fe < 3 + > fluorescent probe and application of the silicon quantum dot-Fe < 3 + > fluorescent probe in detection of glyphosate pesticide residues, belongs to the field of analytical chemistry, and solves the problems that an existing detection method is long in detection time consumption, complex in sample pretreatment and difficult in high-throughput analysis. The preparation method comprises the following steps: introducing a newly prepared sodium ascorbate solution and a 3-aminopropyltrimethoxysilane solution into ultrapure water for reaction; dialyzing the solution in distilled water to remove unreacted solvent, and storing the obtained solution in a dark place at room temperature; carrying out rotary evaporation on the solution until the solution is viscous, pumping by a vacuum pump until the solution is dry, and dissolving by distilled water to obtain a silicon quantum dot solution; and incubating the silicon quantum dot solution and Fe < 3 + > at room temperature to form the silicon quantum dot-Fe < 3 + > fluorescent probe. The preparation method is simple, and reaction products are easy to separate and purify; the method is simple and convenient in glyphosate detection operation, good in selectivity, rapid in response and high in sensitivity, and can be used for rapid and quantitative detection of glyphosate pesticide residues in vegetables.

The invention discloses photocatalytic stereoselective E-type olefination of alkynyl amide and a preparation method of the alkynyl amide. The method is carried out in a water-phase micelle reaction system and is completed under the driving of visible light. According to the method, an alkynyl amide compound is taken as a raw material, sodium ascorbate is taken as a green reducing agent, Ru (bpy) 3 (PF6) 2 or [Ir (dtbpy) (ppy) 2] PF6 is taken as a photocatalyst in a water-phase micelle environment formed by a surfactant lauryl sodium sulfate (SDS), and under the protection of inert gas, catalytic circulation is initiated by visible light irradiation at 20-40 DEG C, so that the alkynyl amide compound is highly selectively converted into an E-type olefin product. The method is mild in condition, simple in step, high in stereoselectivity, environment-friendly and safe to operate, the problem that flammable and explosive reagents or harsh reaction conditions need to be used in a traditional method is solved, and a green and efficient preparation way is provided for preparation of the E-type acrylamide compound.

The invention discloses a preparation method and application of super-amphiphilic molecular nanoparticles under a high solid condition, and belongs to the technical field of biology. The preparation method comprises the following steps: preparing a high-concentration curcumin-cyclodextrin inclusion compound by combining a heating stirring method with ultrasound; adding the inclusion compound into a high-concentration alkalized sodium caseinate solution, and continuously adding food-grade sodium hydroxide to maintain the pH value of the system; performing ultrasonic treatment on the mixture, acidifying, performing high-pressure homogenization, centrifuging, adding maltodextrin, and performing spray drying to obtain the curcumin nanoparticles. And redissolving the obtained nanoparticles, and adding sodium erythorbate, sodium hexametaphosphate, sucrose and polyglycerol fatty acid ester to obtain the beverage. According to the powder prepared by the method, the content of super-amphiphilic molecule solids is remarkably increased, so that the cost of large-scale spray drying is reduced; the beverage obtained by redissolving has relatively good physical and chemical stability and shelf life.

The invention discloses a method for extracting tellurium from a sodium tellurite solution through electrodeposition, and belongs to the technical field of non-ferrous metal hydrometallurgy. The method comprises the following steps: dissolving crude tellurium dioxide in a sodium hydroxide solution at 60-90 DEG C to prepare a sodium tellurite electrolyte containing 200-240 g / L of tellurium and 90-110 g / L of sodium hydroxide; in the electrodeposition process, a composite additive composed of sodium ascorbate, pentasodium diethylenetriamine pentaacetate, sodium citrate and polyvinylpyrrolidone is synchronously added into the electrolyte. And carrying out electrodeposition for 14-15 days under the conditions that the current density is 40-60A / m, the voltage is 15-30V and the temperature is 15-30 DEG C. Through the synergistic effect of the composite additive, tellurite radicals in the anode region are remarkably inhibited from being oxidized into insoluble sodium tellurate, heavy metal impurity ions in the electrolyte are strongly complexed, and therefore the direct recovery rate of tellurium is increased to 90% or above while the better current efficiency is kept, and the purity of the obtained tellurium ingot reaches 99.95% or above.

This invention belongs to the field of food processing technology and provides an antioxidant jam and its preparation method. The invention employs a synergistic design of a pectin-calcium ion microgel and a core-shell microcapsule bilayer microstructure. The core of the core-shell microcapsule contains ascorbic acid or sodium ascorbate, while the shell contains a pectin-calcium ion crosslinking network. This design helps to balance processing adaptability, structural stability, and preservation of antioxidant activity. It solves the technical challenges of the coupling contradiction between gel strength and water-free properties after the introduction of the ion-crosslinked microstructure, the synergistic optimization of microcapsule encapsulation efficiency and controllable release, and the thermosensitive degradation of ascorbic acid under heat treatment and shear conditions. This invention has broad application value in functional food fields such as jams, jellies, and baking fillings.

The present application relates to the technical field of gene sequencing, in particular to an imaging reagent and a kit for a multi-cycle nucleic acid sequencing reaction based on fluorescence. In the imaging reagent, the synergistic effect of the combination of ethyl 3,4-dihydroxybenzoate, 4-hydroxy-3-methoxyacetophenone and sodium ascorbate reduces the generation of free radicals, inhibits nucleic acid damage during the imaging process, reduces phasing and pre-phasing, and ultimately improves the accuracy of long read sequencing. In order to improve the sequencing read length, three functional components, namely antioxidants, fluorescence quenching inhibitors and free radical scavengers, are added to the traditional imaging reagent. Compared with the existing imaging protectants, the present application creatively selects three antioxidants, namely ethyl 3,4-dihydroxybenzoate, 4-hydroxy 3-methoxy acetophenone and sodium ascorbate, for compounding, so as to exert a synergistic effect and eliminate the need for adding fluorescence quenching inhibitors and free radical scavengers.

The invention belongs to the technical field of health care products or medicines, and discloses a high-purity alkaline compound vitamin C composition, and a liposome soft capsule and a preparation method thereof. The invention firstly provides a composition composed of sodium ascorbate, sodium erythorbate and the like, and the sodium erythorbate and trisodium citrate are utilized to synergistically construct a chemical dual-stability barrier. On the basis, the composition is further encapsulated through a low-temperature oxygen-free liposome preparation process to form a physical protection barrier capable of improving bioavailability, and the composition is prepared into a soft capsule dosage form. According to the preparation method disclosed by the invention, low-temperature and inert gas protection measures run through all the time, and the preparation method not only comprises superfine grinding and mixing of the core composition, but also comprises low-temperature and high-pressure homogenization and subsequent filling processes of the lipidosome. The final product is alkalescent and good in stability, and the absorption rate of active ingredients is remarkably improved through a liposome delivery system.

The invention discloses zero-lactose formula goat milk powder for pets and a preparation method of the zero-lactose formula goat milk powder, and relates to the technical field of preparation of goat milk powder. Comprising the following raw materials: raw goat milk, lactase L3000, sodium citrate, low-sensitivity whey protein, medium-chain triglyceride, fructo-oligosaccharide, galactooligosaccharide, modified sodium caseinate, modified chicken flavor peptide, composite minerals, composite vitamins, trehalose, sodium ascorbate, microcrystalline cellulose and polyglycerol fatty acid ester. According to the invention, the modified chicken flavor peptide is added, the chitosan oligosaccharide and gamma-aminobutyric acid modified chicken flavor peptide in the modified chicken flavor peptide realize long-acting retention of natural chicken flavor by virtue of a double-layer coating structure, the flavor is prevented from being oxidized and losing aroma during processing and storage, and the ingestion willingness of pets is remarkably improved; the chitosan oligosaccharide can adjust the balance of intestinal flora of the pet, and the gamma-aminobutyric acid can relieve the stress reaction of the pet during ingestion, so that the feed additive is suitable for weaned or food-changing pets, and achieves triple effects of aroma enhancement, intestine protection and relieving.

The invention discloses hydrogel for sweat glucose detection, a preparation method of the hydrogel and a spontaneous perspiration type hydrogel sweat glucose detection sensor, and relates to the field of biological fluid characteristic object recognition, and the preparation method of the hydrogel comprises the steps that firstly, phytic acid and aniline monomers serve as raw materials, and phytic acid doped polyaniline powder is prepared; mixing Mxene, methylene blue, sodium ascorbate, the phytic acid doped polyaniline powder, acrylamide and N, N '-methylene bisacrylamide in deionized water to obtain a mixed solution; dropwise adding an ammonium persulfate solution into the mixed solution, stirring and standing to obtain a hydrogel intermediate; and finally, sequentially activating and modifying the hydrogel intermediate, and dispensing glucose oxidase to obtain the hydrogel for sweat glucose detection. The hydrogel prepared by the invention has high ion / electron conductivity, enzyme immobilization ability and mechanical flexibility. The interface charge transfer efficiency can be improved and multifunctional integration can be realized by integrally designing the electrode and a carbon electrode into a sensor of an interdigital structure.

The invention relates to the technical field of microbial preparations, and discloses a lactobacillus salivarius preparation, which comprises a core material and a wall material, the core material comprises a lactobacillus salivarius suspension and a protective agent solution, and the wall material is 1-3% by mass of a sodium alginate aqueous solution or 5-10% by mass of a whey protein aqueous solution. The protective agent solution comprises the following components in percentage by mass: 5-8% of glycerol, 10-15% of skim milk powder, 0.3-0.8% of sodium ascorbate and 6-10% of trehalose. By systematically screening and optimizing the components and proportion of the protective agent, an efficient protective system is constructed, the survival rate of thalli in the freeze-drying process and the stability of the preparation in long-term storage are remarkably improved, the preparation can quickly recover and maintain the healthy acidic environment of vagina, and the preparation has a good application prospect. Breeding of various common harmful bacteria is remarkably inhibited, and the specific effects of adjusting vagina micro-ecological balance and preventing and assisting in treating related gynecological inflammation are achieved.

This invention relates to the field of anti-corrosion reagent technology, specifically disclosing a method for manufacturing a solid oxygen-removing, bactericidal, corrosion-inhibiting, and scale-inhibiting agent for seawater oil well pipelines. The agent comprises a three-layer core-shell structure: the core layer is composed of a copolymer hydrogel of 2-acrylamido-2-methylpropanesulfonic acid and N-vinylcaprolactam, loaded with sodium isoascorbate and a copper-L-histidine complex; the middle layer is composed of 3-aminophenylboronic acid-functionalized silica nanoparticles and catechol linked by dynamic borate ester bonds; and the shell layer is composed of a copolymer of 3,4-dihydroxyphenylalanine and 1H,1H,2H,2H-perfluorodecyl acrylate coating a corrosion-inhibiting and bactericidal complex. This invention overcomes the pH conflict between oxygen removers and corrosion inhibitors in traditional reagents through the synergistic effect of the core-shell structure and dynamic bonds, achieving integrated functions of oxygen removal, bactericidal action, corrosion inhibition, and scale inhibition. It effectively inhibits microbial corrosion, reduces the risk of scaling, extends the lifespan of seawater pipelines, and is suitable for complex marine conditions.

The invention discloses a hairpin type DNA-copper cluster probe for rapid ratio fluorescence detection of Hg < 2 + > and a preparation method, the hairpin type DNA-copper cluster probe contains a hairpin type DNA template (hpDNA) capable of emitting strong red fluorescence and weak blue fluorescence at the same time, and the sequence of the hairpin type DNA template is 5 '-TTTTTTTTTTTTTTTTTTTTT TTTTCGCGCGATATATCGCGCG-3'. The method comprises the following steps: preparing a single-stranded DNA aqueous solution by using a 3-morpholine propanesulfonic acid buffer solution, heating the single-stranded DNA aqueous solution in a constant-temperature water bath kettle, cooling to room temperature, and refrigerating and storing in a refrigerator to form an hpDNA template solution; adding a copper sulfate solution into the hpDNA template solution, and incubating at constant temperature to obtain a mixed solution; and adding a sodium ascorbate (SA) solution into the mixed solution, reacting at a constant temperature, and reducing Cu < 2 + > coordinated on the hpDNA template by sodium ascorbate to obtain the hairpin type DNA-copper cluster probe for rapid ratio fluorescence detection of Hg < 2 + >. The hairpin DNA-copper cluster (hpDNA-CuNCs) probe can be used for rapid ratio fluorescence detection of Hg < 2 + >. The hpDNA-CuNCs probe has excellent selectivity on Hg < 2 + >, is used for rapid and sensitive detection of trace Hg < 2 + > in an actual water body sample, and has an accurate detection result.