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460 results about "Taurine" patented technology

Taurine (/ˈtɔːriːn/), or 2-aminoethanesulfonic acid, is an organic compound that is widely distributed in animal tissues. It is a major constituent of bile and can be found in the large intestine, and accounts for up to 0.1% of total human body weight. Taurine is named after the Latin taurus (a cognate of the Greek ταῦρος) which means bull or ox, as it was first isolated from ox bile in 1827 by German scientists Friedrich Tiedemann and Leopold Gmelin. It was discovered in human bile in 1846 by Edmund Ronalds.

Amino acid frosted cleaning composition as well as preparation method and application thereof

The invention provides an amino acid frosted cleaning composition as well as a preparation method and application thereof. The amino acid frosted cleaning composition comprises a surfactant, an amino acid composition, a thickening agent, a humectant, an antioxidant, a pH regulator and water, the surfactant is a combination of cocoyl glycinate, cocamidopropyl hydroxy sulfobetaine, sodium cocoyl methyl taurine taurate, sulfonic acid hydroxypropyl ester lauryl glucoside cross-linked polymer sodium and glycolipid. According to the invention, a mild surfactant system with amino acid as a main component is adopted, so that the shampoo has rich and fine foam, quick foaming performance and easy washing performance, and the skin feeling is smooth and soft after washing. In addition, the system contains suspended crystal frosted particles formed by self-assembly of the amino acid composition, the appearance is novel, the better efficacy performance is achieved, and meanwhile the cleaning effect and the use comfort are improved.
Owner:NOX BELLCOW COSMETICS CO LTD

Oyster peptide and application thereof in preparation of product for improving alcoholic liver injury

The invention relates to the technical field of preparation of marine bioactive substances and functional foods, in particular to oyster peptide and application thereof in preparation of products for improving alcoholic liver injury. According to the invention, oyster peptide raw materials rich in natural taurine are adopted, scientific formula design and natural plant alcohol effect dispelling and liver protecting components are adopted, and adverse reactions after drinking, such as hangover, fatigue and alcoholic liver injury, are effectively relieved; according to the oyster peptide tabletted candy formula with the functions of dispelling the effects of alcohol and protecting the liver, provided by the invention, functional components all meet design requirements through detection.
Owner:QUANZHOU MARINE BIOTECHNOLOGY IND RES INST

Long-acting antibacterial female care gel and preparation method thereof

The invention relates to the technical field of female private care, and discloses a long-acting antibacterial female care gel and a preparation method thereof.According to the care gel, natural plant extracts serve as core active ingredients, microbial fermentation products, macromolecular thickening agents and functional auxiliary materials are supplemented, and a synergistic system is formed through scientific compatibility; wherein the core components comprise compound antibacterial components such as cranberry extract, gallnut extract and pomegranate peel extract, nourishing and repairing components such as radix puerariae extract and southern dodder seed extract, and stable components such as ammonium polyacryloyldimethyl taurine. By optimizing the formula composition and the preparation process, the technical problems that existing female care gel is short in bacteriostasis time and poor in biocompatibility are solved, and the female care gel has the multiple effects of long-acting bacteriostasis, mildness, no irritation, nourishing, repairing, moisturizing, lubricating and the like. The preparation method adopts the processes of segmented extraction, gradient mixing and low-temperature sterilization, ensures the stability of active ingredients and the uniformity of a gel system, and is suitable for large-scale production.
Owner:AMERICANA (LIAONING) PHARM CO LTD

Composition containing lutein, zeaxanthin, astaxanthin, anthocyanins and proanthocyanidins

A trace element supplement consisting of lutein, zeaxanthin, astaxanthin, anthocyanins, and proanthocyanidins is designed to improve retinal health in children and adolescents, relieve eye strain, and slow the progression of myopia. The daily dose is 1–20 mg lutein, 0.2–4 mg zeaxanthin, 0.5–8 mg astaxanthin, 10–700 mg taurine, and 0.5–8.5 mg zinc; the nighttime dose is 1–100 mg eyebright extract, 10–300 mg chamomile extract, 1–200 mg anthocyanins, and 1–500 mg proanthocyanidins.
Owner:LITTLE UMBRELLA LTD

Ginseng leaf solid beverage and preparation method thereof

The invention discloses a ginseng leaf solid beverage and a preparation method thereof. The ginseng leaf solid beverage is prepared from the following components in parts by weight: 15 to 22 parts of ginseng leaf extract liposome, 12 to 14 parts of ginseng leaf extract, 6 to 8 parts of compound peptide powder, 10 to 14 parts of compound soluble dietary fiber, 0.21 to 0.25 part of taurine, 5 to 7 parts of compound sugar alcohol, 0.2 to 0.4 part of tea polyphenol, 0.4 to 0.6 part of citric acid, 0.1 to 0.3 part of sweetening agent, 0.4 to 0.6 part of edible essence and 0.8 to 1.2 parts of stabilizer. According to the ginseng leaf solid beverage and the preparation method thereof provided by the invention, ginseng leaf active ingredients are introduced in the form of lipidosome powder, and the ginseng leaf active ingredients, the ginseng leaf extract, the composite peptide powder, the composite soluble dietary fibers, a sugar alcohol system and the like are subjected to formula synergy, so that the comprehensive improvement of stable activity, improved taste, stable brewing and dosage form and excellent efficacy is realized; high-value, stable and acceptable application of ginseng, especially ginseng leaf resources, in a solid beverage form is realized, and industrialization is facilitated.
Owner:SICHUAN GUOPINTANG FOOD CO LTD

Probiotic composition for improving immunity and preparation method thereof

The invention provides a probiotic composition for improving immunity and a preparation method thereof, and belongs to the technical field of probiotics. The preparation method comprises the following steps: fermenting selenium-enriched nostoc sphaeroides through selenium-enriched saccharomycetes to extract selenium-enriched nostoc sphaeroides polysaccharide and selenium-enriched nostoc sphaeroides protein peptide, mixing with traditional Chinese medicine polysaccharide obtained by extracting astragalus membranaceus, rhodiola rosea, codonopsis pilosula and pseudo-ginseng, and reacting with ferric salt to prepare a polysaccharide-Fe / selenium compound; solid residues are mixed and fermented, and active protein peptide is prepared from the solid residues and selenium-rich nostoc sphaeroides protein peptide; the probiotic composition capable of improving immunity is prepared by extracting a polysaccharide-Fe / selenium compound and a polysaccharide-Fe / selenium compound through an organic solvent, extracting a permeate through an organic solvent to obtain an active component, collecting a bacterial liquid, mixing and embedding the bacterial liquid in the polysaccharide-Fe / selenium compound and sodium alginate, and uniformly mixing the bacterial liquid with the active protein peptide, the active component, taurine and ginsenoside Rg3, so that the probiotic composition capable of improving immunity can play good anti-inflammatory, anti-oxidation, immunoregulation, anti-tumor, anti-virus and other roles, and has a good application prospect. Wide application prospects are realized.
Owner:余昭军

Composite inducer for promoting attachment and metamorphosis of bivalve mollusk larvae and application of composite inducer

The invention discloses a composite inducer for promoting adhesion and metamorphosis of marine bivalve mollusk larvae and an application method of the composite inducer. The composite inducer for promoting adhesion and metamorphosis of the marine bivalve mollusk larvae comprises glutamine, glutamic acid, potassium chloride, calcium chloride and taurine, and the concentration ratio of the glutamine to the glutamic acid to the potassium chloride to the calcium chloride to the taurine is 1: 1: 2 * 10: 1.7 * 10: 4. According to the application, glutamine, potassium ions, calcium ions, glutamic acid and taurine are matched, the application effect of the glutamine, the potassium ions, the calcium ions, the glutamic acid and the taurine in the aspect of improving the attachment and metamorphosis rate of the shellfish larvae is defined, the technical blank of multi-component cooperative regulation and control of the attachment and metamorphosis of the shellfish at present is filled, a new solution is provided for bivalve shellfish fry production, and the application prospect is wide. The method is of great significance in promoting healthy development of the mariculture industry.
Owner:DALIAN OCEAN UNIV

High-foaming self-thickening amino acid cleaning composition and preparation method thereof

The invention provides a high-foaming self-thickening amino acid cleaning composition and a preparation method thereof, and relates to the technical field of cosmetics. The high-foaming self-thickening type amino acid cleaning composition is prepared from the following raw materials in percentage by mass: main surfactants: 15%-20% of potassium cocoyl glycinate, 0.5%-2.0% of sodium cocoyl amino propionate and 0.05%-2% of sodium lauroyl glutamate; the auxiliary surfactant comprises the following components in percentage by weight: 1.2%-1.8% of sodium lauroamphoacetate, 1.8%-3.6% of lauryl hydroxyl sulfobetaine, 0.5%-1.5% of sodium methyl cocoyl taurate and 0.5%-1.5% of lauryl glucoside; and 0.5%-1.8% of an acrylic ester copolymer. The cleaning composition is free of fatty acid components, small in irritation, rich and dense in foam, good in foam performance, high in cleaning power, good in flushing performance, free of false slip after flushing and good in stability.
Owner:SHANDONG HUAWUTANG BIOLOGICAL TECHNOLOGY CO LTD

Composition for external preparation for skin, containing composite microneedle containing polymer active ingredient

Provided is a novel means for delivering an active ingredient into the skin. An external preparation composition for the skin, which is characterized by containing composite microneedle-like crystals in which a polymer active ingredient is included in crystals of a biosoluble substance; a method for producing a taurine composite microneedle-like crystal in which a polymer active ingredient is encapsulated in a crystal, the method being characterized by comprising a step for inducing crystal growth in an environment in which an aqueous solution (A) in which taurine, which is a biosoluble substance, is dissolved in water, and a liquid substance (B) having a low solubility in taurine are mixed or brought into contact with each other, by dissolving or dispersing a polymer active ingredient in the aqueous solution (A) or the liquid substance (B), the polymer active ingredient is enclosed in the crystal along with the growth of the crystal.
Owner:COSMED PHARMA

Eye wash containing PDRN and EGT and preparation method thereof

PendingCN121668183ASenses disorderAntipyreticXerophthalmiaCornea repair
The invention discloses a PDRNamp and a method for preparing the PDRNamp. The invention discloses EGT eye wash as well as a preparation method and application thereof, and belongs to the technical field of eye care products. The eye wash is prepared from the following active components in percentage by mass: 0.001 to 0.01 percent of PDRN, 0.03 to 0.1 percent of EGT (Ergothioneine), sodium hyaluronate, sodium chloride, taurine and the like, wherein the mass percent of the PDRN is 0.001 to 0.01 percent, and the mass percent of the EGT is 0.03 to 0.1 percent. Through the synergistic effect of PDRN and EGT, the product has excellent cornea repairing capacity and a powerful anti-oxidation function at the same time, and the moisturizing and soothing effects are enhanced by compounding sodium hyaluronate and taurine. The obtained eye washing liquid is an isotonic solution with neutral pH, is mild and non-irritating, does not contain preservatives, can effectively achieve multiple nursing effects of eye cleaning, moisturizing, repairing, anti-inflammatory and anti-oxidation, and is suitable for relieving xerophthalmia, assisting cornea repair and daily anti-oxidation nursing of eyes.
Owner:SHANGHAI PUAISHI BIOTECHNOLOGY CO LTD

Astragaloside synergistic composition as well as preparation method and application thereof

The invention discloses an astragaloside synergistic type composition as well as a preparation method and application of the astragaloside synergistic type composition. Comprising the following components: 8 to 16 parts of astragaloside, 20 to 40 parts of a honeysuckle flower extract, 10 to 20 parts of L-carnitine, 0.1 to 0.5 part of selenium yeast, 3 to 8 parts of diammonium glycyrrhizinate, 5 to 15 parts of taurine, 8 to 20 parts of a fructus forsythiae extract, 2 to 7 parts of vitamin E, 12 to 32 parts of hydroxypropyl-beta-cyclodextrin, 2 to 10.5 parts of maltodextrin, 1 to 7 parts of Arabic gum, 10 to 20 parts of lactose, 1 to 3 parts of zinc gluconate and 2 to 5 parts of magnesium stearate. 1-3 parts of vitamin C, 1-5 parts of xanthan gum and 1-3 parts of lecithin. The composition has a wide application prospect in preparation of veterinary drugs or veterinary food additives.
Owner:JIANGXI CHENGBIXIN BIOTECHNOLOGY CO LTD

A method for preparing high-bionic bovine bezoar by using 3D printing technology and application

The application relates to the technical field of biological pharmacy, and discloses a method for preparing high-bionic bovine bezoar by using a 3D printing technology and application. The preparation raw material of the high-bionic bovine bezoar comprises the following components: fermented bovine bile, saturated calcium hydroxide, hydroxypropyl methyl cellulose, bilirubin, cholic acid, deoxycholic acid and taurine; wherein the fermented bovine bile is obtained by fermenting bovine bile by using escherichia coli. The high-bionic bovine bezoar prepared by using the preparation raw material to perform 3D printing can be comparable to natural bovine bezoar in terms of components, effects and appearance, the main pharmaceutical components can be adjusted according to actual requirements, the production cost of the bovine bezoar can be greatly reduced, and the demand of people for the bovine bezoar can be met.
Owner:麒牛药业(珠海横琴)有限公司

Method for determining taurine in magnesium acetyltaurate

The invention provides a method for detecting taurine in magnesium acetyltaurate, which comprises the following steps: (1) derivatization treatment: carrying out derivatization reaction on a derivatization reagent and magnesium acetyltaurate containing taurine under an alkaline condition to obtain a derivatization product; (2) detection: detecting the derivatization product in the step (1) by adopting a high performance liquid chromatography-ultraviolet detector; wherein the derivatization reagent is selected from the group consisting of 2, 4-dinitrofluorobenzyl cyanide. The determination method has the advantages of high sensitivity, good specificity, simple operation, high accuracy, good reproducibility, good stability and low cost, improves the quality standard of taurine detection in magnesium acetyltaurate, can strictly control the quality of taurine in magnesium acetyltaurate, ensures the safety and reliability of magnesium acetyltaurate, and has a wide application prospect. The practical significance is realized.
Owner:苏州博研医药科技有限公司

Wrinkle-removing cream containing sequoia stem fermentation product and preparation method of wrinkle-removing cream

PendingCN121512898ACosmetic preparationsToilet preparationsEthylhexyl palmitateButanediol
The invention relates to the technical field of cosmetics, and particularly discloses anti-wrinkle cream containing sequoia stem fermentation products and a preparation method of the anti-wrinkle cream. The wrinkle removing cream containing the sequoia stem fermentation product is prepared from the following raw materials in percentage by mass: a material A: glycerol, butanediol, p-hydroxyacetophenone YS028, an ammonium acryloyldimethyl taurate / VP copolymer, p-hydroxyacetophenone YS008 and the balance of water; the material B is prepared from cetostearyl alcohol, an emulsifying agent MONTANOV202, butyrospermum parkii butter, isopropyl myristate, C10-18 fatty acid triglyceride, polydimethylsiloxane, ethylhexyl palmitate and XIAMETERPMX-0345Z Fluid; the material C is prepared from a material D and a material E; the material C is prepared from a sequoia stem fermentation product, Naturalpenet 2020 and SEPIGEL305; the material D is prepared from YONOME SPE II, Alps mountain leucas, ULA-L1004 coated ceramide, anti-wrinkle base peptide, super-oinmetidyl-D2, Chinese prescription hexyl A powder, XYREPIOR, annoine TM, essence and methyl dihydrojasmonate; the material D is prepared from YONOME SPE II, Alps mountain leucas, ULA-L1004 coated ceramide, anti-wrinkle base peptide, super-oinmetidyl-D2, Chinese prescription hexyl A powder, XYREPIOR, annoine TM In addition, the preparation method has the advantage of improving the wrinkle removing effect of the wrinkle removing cream.
Owner:SHANDONG YUSEN BIOTECHNOLOGY CO LTD

Pharmaceutical composition containing adapalene and benzoyl peroxide and preparation method thereof

PendingCN121818792AHydroxy compound active ingredientsAntisepticsContact dermatitisGlycerol
The invention relates to a pharmaceutical composition, which is prepared from adapalene, benzoyl peroxide, a traditional Chinese medicine extract, an acrylamide and acryloyl dimethyl sodium taurate copolymer, a mixture of isohexadecane and polysorbate 80, docusate sodium, EDTA (Ethylene Diamine Tetraacetic Acid) disodium, glycerol, poloxamer 124, propylene glycol and water, the traditional Chinese medicine extract comprises moutan bark, salvia miltiorrhiza, radix rehmanniae recen, radix sophorae flavescentis, coptis chinensis, rheum officinale, scutellaria baicalensis, menthol and borneol. According to the pharmaceutical composition disclosed by the invention, the synergistic antibacterial and anti-keratosis curative effects of adapalene and benzoyl peroxide can be maintained, and meanwhile, the occurrence rate of local skin dryness, erythema, desquamation, burning heat sensation and contact dermatitis can be remarkably reduced.
Owner:JIANGSU SEMPOLL PHARMA

Composite nut polypeptide solid beverage and preparation method thereof

The invention discloses a composite nut polypeptide solid beverage and a preparation method thereof. The health-care food is prepared from the following components in parts by weight: 20 to 40 parts of walnuts, 15 to 30 parts of cashew nuts, 10 to 25 parts of almonds, 12 to 28 parts of almonds, 8 to 20 parts of hazelnuts, 0.3 to 0.8 part of compound protease, 0.05 to 0.15 part of beta-glucanase, 10 to 20 parts of isomaltooligosacharide, 5 to 15 parts of resistant dextrin, 8 to 18 parts of maltodextrin, 0.1 to 0.3 part of silicon dioxide, 0.05 to 0.15 part of vitamin C, 0.02 to 0.08 part of gamma-aminobutyric acid, 0.03 to 0.1 part of taurine and 2 to 5 parts of natural strawberry powder. And 0.05 to 0.15 part of natural vanilla essence. The invention discloses and provides a composite nut polypeptide solid beverage and a preparation method thereof, a composite enzymolysis technology is adopted, nut protein is hydrolyzed into small-molecule polypeptides with the average molecular weight lower than 1000Da, and the polypeptides have high biological activity and bioavailability.
Owner:JIANGSU HAODE FOOD CO LTD

Sodium hyaluronate composite solution for relieving skin aging and preparation method thereof

The invention relates to the technical field of biomedical materials, in particular to a sodium hyaluronate composite solution for relieving skin aging and a preparation method thereof, the sodium hyaluronate composite solution comprises sodium hyaluronate, taurine, proline, glutamic acid, glycine and valine; sodium hyaluronate has a specific molecular weight, the composite solution has a specific pH value and osmotic pressure, and all the components have a synergistic effect, so that a moist environment is provided for skin, free radicals are removed, collagen synthesis is promoted, and aging phenomena such as skin laxity and wrinkles are improved. The composition can maintain skin moisture for a long time, scavenge free radicals, resist oxidation and promote collagen synthesis to improve skin aging, the preparation process guarantees stable components, the solution is matched with the physiological environment of the skin, and the composition is non-irritant, safe to use and good in anti-aging effect.
Owner:CHANGZHOU INST OF MATERIA MEDICA

Generalized pustular psoriasis diagnostic marker based on metabonomics and application thereof

The invention discloses a generalized pustular psoriasis diagnosis marker based on metabonomics and application of the generalized pustular psoriasis diagnosis marker. The diagnostic marker is prepared from one or more of the following 35 compounds: pyruvic acid, alpha-ketoisovaleric acid, 2-hydroxybutyric acid, 3-hydroxybutyric acid, methane thiophosphoric acid, proline, uracil, tranexamic acid, 4-aminobutyric acid, threonine, scopoletin, dodecanol, N-methyl-L-leucine, L-cysteine-glycine and L-kynurenine. The feed additive is prepared from the following raw materials: 3-hydroxybenzoic acid, allantoin, delta-tocopherol, xylofuranose, glucose-1-phosphoric acid, pyrophosphate, taurine, L-asparagine, phthalic acid, 4-(dimethylamino) azobenzene, 5-tert-butyl-1h-indole-2, 3-dione, quinic acid, glucose, histidine, lysine, palmitic acid, 7-methylguanine, oleic acid and whale acid. The marker can be used for accurately distinguishing patients with generalized pustular psoriasis from healthy people.
Owner:SHANGHAI DERMATOLOGY HOSPITAL

Methods and compositions for methionine restriction

The technology described herein is directed to compositions and methods for reducing levels of methionine. In various aspects described herein are: engineered methionine-reducing probiotic microorganisms; engineered methanethiol-reducing probiotic microorganisms; and engineered taurine-producing probiotic microorganisms. Also described herein are methods of using such engineered microorganisms, such as for reduction of bioavailable methionine or for treatment of a methionine-associated disease or disorder. Also described herein are probiotic dietary supplements, pharmaceutical compositions, and food compositions comprising such engineered microorganisms.
Owner:PETRI BIO INC

Anti-fatigue and joint protection composition for sports people

The invention belongs to the technical field of biological medicines, and particularly discloses an anti-fatigue and joint protection composition for sports people, which comprises the following components in percentage by mass: 10-25% of citrus bioflavonoid, 5-15% of taurine, 15-30% of eggshell membrane powder, 2-8% of curcumin compound, 1-5% of citric acid and the balance of maltooligosaccharide. Under the synergistic interaction of the citrus bioflavonoid, the taurine, the eggshell membrane powder and the curcumin compound, the composition with excellent anti-fatigue and joint protection effects is obtained.
Owner:GUANGZHOU PROCEPT BIOTECH

Whitening composition containing jasmine extract as well as preparation method and application of whitening composition

The invention provides a whitening composition containing a jasmine extract as well as a preparation method and application thereof, and relates to the technical field of cosmetics. The whitening composition is prepared from the following components in parts by weight: 1 to 10 parts of nicotinamide; 0.1 to 5 parts of taurine; 0.1 to 3 parts of lecithin; 0.01 to 2 parts of inositol; 0.01 to 1 part of ceramide NP; 0.1 to 3 parts of tranexamic acid; 0.01-2 parts of glutathione, 0.1-5 parts of a jasmine flower lactobacillus fermentation extract and 20-60 parts of water. By controlling the types and mass ratio of the specific components, especially the mass ratio of lecithin to tranexamic acid, inositol to glutathione, and nicotinamide to taurine to jasmine lactic acid bacteria fermentation extract, the obtained composition not only can inhibit melanin generation and transport, but also can promote permeation of effective components, so that the anti-aging effect of the composition is improved, and the anti-aging effect of the composition is improved. The content of effective components in the skin is increased, so that the absorption effect and the bioavailability of the product are improved.
Owner:GUANGZHOU BURUIS TECHNOLOGY CO LTD

A contact lens containing PDRN and a preparation method thereof

The present application belongs to the technical field of contact lenses, and provides a contact lens containing PDRN and a preparation method thereof. The contact lens is pretreated to obtain a plasma lens; the plasma lens is sequentially soaked in a first PDRN solution, a hyaluronic acid solution, a second PDRN solution and a taurine solution to obtain a semi-finished lens; and the semi-finished lens is crosslinked to obtain the contact lens containing PDRN. Through the design of a multi-layer structure, the present application realizes the synchronous and synergistic implantation of PDRN, hyaluronic acid and taurine in the contact lens. Among them, PDRN activates the A2A adenosine receptor signaling pathway, plays a core therapeutic role in promoting corneal epithelial cell proliferation, inhibiting the release of inflammatory factors and accelerating tissue repair; hyaluronic acid plays a role in lubricating and protecting the cornea; and taurine can scavenge active oxygen free radicals and reduce oxidative stress damage.
Owner:GANSU TIANHOU OPTICAL TECHNOLOGY CO LTD

Ionic liquid for treating androgen-derived alopecia as well as preparation method and application of ionic liquid

The invention discloses an ionic liquid for treating androgen-derived alopecia as well as a preparation method and application thereof, and belongs to the technical field of medicines. Through the composite molecular structure design of the quaternary ammonium salt-taurine ionic liquid, the ionic liquid integrates ROS removal, stem cell activation, efficient transdermal and long-acting retention, so that the ionic liquid can directly act on a core pathological link of androgen-derived alopecia; and safe and efficient treatment without drug combination is effectively achieved.
Owner:UNIV OF SCI & TECH BEIJING

Microelement composite additive for improving reproductive performance of pets

PendingCN122004358AFood processingAnimal feeding stuffBiotechnologyVitamin E Acetate
The invention belongs to the technical field of pet nutrition, and discloses a trace element composite additive for improving the reproductive performance of pets, which comprises the following raw materials: zinc sulfate, sodium selenite, copper sulfate, manganese sulfate, vitamin E acetate, L-lysine hydrochloride, taurine, methionine, selenium yeast and zeolite powder. The zeolite powder is subjected to a specific acid treatment activation process, so that the adsorbability and the stability are improved. The invention also discloses a preparation method of the additive. A three-step mixing process is adopted to ensure the uniformity of the product. The additive is suitable for being added into feed in the breeding period of canine or feline pets, the adding amount of the additive is 0.1-0.5% of the total weight of the feed, and the feeding time is 1 month before breeding and 1 month after breeding. Through scientific proportioning of organic trace elements and inorganic trace elements, in combination with specific amino acids and vitamins, the components have a synergistic effect, so that the pregnancy rate, the litter size and the survival rate of newborn animals of pets are remarkably increased, and meanwhile, the pet feed has good storage stability and use safety.
Owner:BEIJING ZHONGNONG JINTENG BIO-PHARM CO LTD

Plasma protective agent, freeze-drying method for keeping pH of plasma and freeze-dried plasma

PendingCN121313569APowder deliveryInorganic non-active ingredientsHydroxyethyl starchVitamin C
The invention relates to the technical field of freeze-drying preparations, in particular to a plasma protective agent, a freeze-drying method for keeping the pH of plasma and freeze-dried plasma, and the plasma protective agent comprises the following components: an instant protective agent which comprises 5mg / ml of glycine; the feed additive is prepared from sodium dihydrogen phosphate, trehalose, hydroxyethyl starch, polyethylene glycol, mannitol, taurine, tryptophan lysine or glutamic acid. The sustained-release protective agent comprises antioxidant components encapsulated by lipidosome, wherein the antioxidant components comprise glutathione, adenosine and vitamin C. The invention also discloses a preparation method of the sustained-release protective agent. The novel protective agent vitamin C is adopted, the plasma pH adjusting operation is remarkably simplified, and the vitamin C is composed of multiple components with different functions, so that the stability of key components such as blood coagulation factors in plasma is greatly improved.
Owner:BLUE OCEAN TIANYUAN BIOTECHNOLOGY (BEIJING) CO LTD

Composite hydrogel for medical auxiliary materials and preparation method thereof

The invention belongs to the technical field of medical materials, and particularly relates to a composite hydrogel for medical dressings, the hydrogel is composed of carrageenan, locust bean gum, polyvinyl alcohol, polyvinylpyrrolidone, potassium chloride, diglycerol and water, and functional components such as dragon fruit powder and taurine can be selectively added. The preparation method comprises the following steps: dissolving PVA in hot water, adding mixed powder of carrageenan and locust bean gum, uniformly stirring and swelling, adding PVP, KCl, diglycerol and other functional components, heating to form uniform and clear composite sol, and cooling to obtain physical crosslinking gel with good adhesion and resilience; and inducing PVP and PVA in the gel to be further crosslinked by adopting 60Co gamma ray irradiation, so as to obtain a final product with higher mechanical strength and more stable structure. The hydrogel is high in transparency, can be tightly attached to skin or tissue, has excellent biocompatibility, moisturizing performance and structural stability, and is suitable for wound dressing.
Owner:河南省科学院同位素研究所有限责任公司

A traditional Chinese medicine composition for treating intrahepatic cholestasis and application thereof

This invention relates to a traditional Chinese medicine combination for treating intrahepatic cholestasis, which is made from the following raw materials in parts by weight: Artemisia capillaris and Glycyrrhiza uralensis 5:1 and 3:1. This invention also provides the preparation of the above-mentioned medicine and its use in treating intrahepatic cholestasis. Its advantages are: the traditional Chinese medicine composition of this invention (Artemisia capillaris and Glycyrrhiza uralensis decoction) has a significant ameliorative effect on intrahepatic cholestasis (non-obstructive type) induced by a 1% CA-containing diet in mice. Artemisia capillaris and Glycyrrhiza uralensis decoction can alleviate weight loss in mice and improve liver necrosis; significantly reduce serum ALT and ALP levels in mice; reduce the content of total bile acids in the liver and decrease the proportion of toxic bile acid taurine deoxycholic acid (TDCA) in the bile acid pool; upregulate liver BSEP protein expression to promote bile acid efflux; and downregulate liver NLRP3 protein expression to alleviate liver necrosis.
Owner:裘福荣 +1

Highly active conjugated bile acid-deconjugating enzyme and use thereof

The present invention addresses the problem of: developing a method capable of noninvasively sampling and analyzing intestinal mucosa bacteria; analyzing the intestinal bacteria, especially intestinal mucosa bacteria on the basis of the method; and developing a therapeutic method for diseases occurring in the intestinal tract for which therapeutic methods have not been established. The inventors of the present invention have found that bacteria contained in a cotton swab (swab) sample on the feces surface exhibit a bacterial flora composition similar to that of bacteria existing in the intestinal mucosa; and, as a result of analysis based on the finding, have clarified that Adlercreutzia, which has not been reported until now as a mucosa-related bacterium, lives in the large intestinal mucosa layer, produces taurine, which is a strong anti-inflammatory compound, by the action of the bile acid-deconjugating enzyme, and alleviates enteritis, thereby completing the present invention. In other words, the present invention can provide a composition having an anti-inflammatory effect, which includes a bacterium of the genus Adlercreutzia, or a bile acid-deconjugating enzyme that is derived from a bacterium of the genus Adlercreutzia.
Owner:KEIO UNIV +1