14 results about "Ethylamine" patented technology

The invention relates to the field of organic chemistry, and particularly discloses a synthetic method of berberine hydrochloride. The synthesis method of berberine hydrochloride comprises the following steps: S1, carrying out reductive amination reaction on bromohomopiperony lamine and o-veratraldehyde to synthesize an intermediate II; s2, carrying out Suzuki coupling reaction on the intermediate II and an organic boron compound under the catalysis of a palladium metal organic matter to synthesize an intermediate III; s3, the intermediate III and organic chloride are subjected to an amino chlorination reaction, and an intermediate IV is synthesized; s4, carrying out intramolecular atom transfer radical addition and intramolecular Friedel-Crafts alkylation cascade reaction on the intermediate IV in a mixed solvent under the catalysis of a copper catalyst to synthesize an intermediate V; and S5, carrying out oxidative aromatization reaction on the intermediate V and iodine under the catalysis of alkali to synthesize berberine hydrochloride. The synthesis process is simpler, reaction conditions are easier to control, the yield is high, and the method is suitable for industrial production.

The invention relates to the field of textile printing materials, and discloses a preparation method of water-based digital printing bottoming white adhesive cement, which comprises the following steps: mixing water-based acrylate emulsion with an auxiliary agent and a macromolecular quaternary ammonium salt color fixing agent to obtain a premix; mixing the premix with filling powder to obtain dispersion liquid; and adding a curing agent and a thickening agent into the dispersion liquid and mixing. The macromolecular quaternary ammonium salt color fixing agent is prepared by reacting an organic silicon modified allylamino phosphorus-containing bromine substituent and bis (dimethylamino) phosphoric acid hydrogenated cardanol ester; the organic silicon modified allylamine phosphorus-containing bromine substituent is prepared by preparing the allylamine phosphorus-containing bromine substituent from allylamine, phenyl dichlorophosphate and 2-bromoethylamine hydrobromide as raw materials and then reacting the allylamine phosphorus-containing bromine substituent with heptamethyltrisiloxane. The white rubber cement prepared by the preparation method is bright in color and clear in pattern, can be recycled and reused, and has the advantages that the white rubber cement is easy to prepare, the cost is low, and the application prospect is wide. The color fixing fastness, the flame-retardant and fire-proof performance, the net blocking prevention performance and the hand feeling comfort degree are good.

This invention discloses a room-temperature phase pyroelectric material and its preparation method, relating to the field of pyroelectric material technology, with the chemical formula C4H. 14 N₂OPbCl₄ is prepared as follows: 2-Dimethylaminoethylamine is cooled and stirred in an ice-water bath, then hydrogen peroxide solution is added dropwise while stirring. After the reaction, the resulting reaction solution is vacuum dried to obtain the nitrogen oxide of 2-dimethylaminoethylamine. The nitrogen oxide of 2-dimethylaminoethylamine and lead chloride are added to a concentrated hydrochloric acid solution, heated in an oil bath, and stirred to obtain a pyroelectric material. The pyroelectric material of this invention has a perovskite structure and undergoes a reversible phase transition reaction at a phase transition temperature of 27°C. During the phase transition, a current is generated at the polar axis of the crystal. The phase transition temperature at room temperature allows the pyroelectric material to operate within a relatively stable temperature range, providing reliable energy collection performance and showing great application value in waste heat utilization, self-sustaining systems, and other fields.

The present invention discloses an antibacterial compound of Formula 1 or pharmaceutically acceptable salt thereof:wherein X is CH, S, CH—NH2;R1 is C1-C8 alkyl, substituted alkyl, alkyl amine, substituted amine; preferably R1 is methyl, ethyl, propyl, butyl, pentyl, isopropyl, isobutyl, methyl amine, ethylamine, propylamine, isopropyl amine, isobutylamine, N-ethylprop-2-yn-1-amine, N-isopropyl propane-1,3-diamine, N1-isopropyl ethane-1,3-diamine, 1-butyl-2-methylguanidine, N1-ethyl-N1-propylethane-1,2-diamine, cyclobutyamine, phosphate, sulphate;R2 is hydrogen, alkyl, substituted alkyl; preferably R2 is methyl, propyl, isopropyl;R3 is hydrogen, alkyl, substituted alkyl; and preferably R3 is methyl, propyl, isopropyl.The Formula 1 or pharmaceutically acceptable salt thereof is an imidazole glycerol phosphate dehydratase (IGPD) inhibitor and treats or prevents or ameliorates tuberculosis.

The invention discloses a preparation method of deep-color isopropyl ethyl thiamine ester, which comprises the following steps: taking 200g of isopropyl ethyl thiamine ester base material, adding 5g of 8% hydrogen peroxide (the effective HO accounts for 0.2%) under the stirring conditions of 35 DEG C and 250rpm, stirring for 10 minutes, adding 0.3-3.4 g of 70% monoethylamine, and reacting at constant temperature for 30 minutes to obtain a deep-color isopropyl ethyl thiamine ester product. According to the method, continuous controllable change of the color of the thiamine ester from light red yellow to dark red brown is realized by accurately controlling the ratio and the reaction condition at 35 DEG C, the deviation of the main peak of the product chromatography is less than or equal to 0.5%, layering and precipitation are avoided after standing in a dark place for 8 hours, the loss of main components is extremely low, the process stability is high, and the method is suitable for industrial production.

The present application relates to a kind of preparation methods of pethoxamid, comprising the following steps: isobutyryl benzene and 2-ethoxyethylamine are reacted, and intermediate 2 is obtained;Then intermediate 2, chloroacetyl chloride, organic solvent are reacted, after reaction, separation is carried out, and pethoxamid pure product is obtained.Belong to the technical field of pesticide chemical engineering.The present application uses continuous flow tubular reactor in step 1, preferred catalyst, good catalytic effect, short reaction time, high reaction efficiency;In step 2, continuous flow microchannel reactor is used, the yield of product obtained is high and high purity, high safety, high reaction efficiency, with good application prospect.

The application provides a kind of floatation reagent and its preparation method, relate to mineral processing technical field.A kind of floatation reagent, including the following weight parts raw materials:ethylamine 2-3 parts, medium long carbon chain fatty amine 3-4 parts, fatty acid salt 2-3 parts, diesel oil 0.5-1 part.The floatation reagent prepared by the application has significantly higher selectivity to feldspar than quartz, can realize the floatation separation of feldspar and quartz under neutral conditions, effectively alleviates the problem of environmental pressure caused by the separation of feldspar and quartz under strong acid and strong base conditions in existing research.

The invention relates to the technical field of fluororubber, and discloses a solvent-resistant flame-retardant fluororubber material and a preparation process thereof. The fluororubber material comprises the following raw materials: 90-110 parts of fluororubber, 30-40 parts of silicon fluoride rubber, 20-25 parts of a flame-retardant filler, 5-8 parts of a plasticizer, 2-3 parts of a vulcanizing agent and 1-2 parts of triallyl isocyanurate. The preparation method of the plasticizer comprises the following steps: adding 2, 2, 2-trifluoroethylamine into epoxidized soybean oil, heating to 80-85 DEG C, and stirring to react for 6-8 hours to obtain the plasticizer; the preparation method of the flame-retardant filler comprises the following steps: coating aluminum hydroxide with epoxy silane coupling agent modified silicon dioxide to obtain epoxy modified composite filler; and 2, 2, 2-trifluoroethylamine is used for modification, such that the flame-retardant filler is obtained. The prepared fluororubber material has excellent mechanical properties and toughness, and also has excellent flame retardance.

The invention relates to the technical field of chemical engineering, in particular to a production process of N-ethyl-3-carbamoyl-4-methyl-6-hydroxy-2-pyridone, which comprises the following steps: S1, condensation ring closure; s2, separation and purification; s3, hydrolyzing, diluting and centrifuging; and S4, recovery of concentrated sulfuric acid. The method has the advantages that the preparation process can be continuous and environment-friendly, the cost of raw materials can be greatly reduced, the sulfuric acid and the monoethylamine are recycled, and the byproduct ethanol is produced.

The application relates to the field of corrosion prevention technology, and particularly relates to a preparation process of heavy-duty anticorrosive paint for building bridges, which introduces a self-repairing prepolymer into water-based epoxy resin as a base material to improve the durability, uses composite basalt flakes as fillers, introduces diluents and penetrants as assistants under the action of a water-based amine curing agent, grows nanometer silicon dioxide on the surface of the basalt flakes in situ to obtain pretreated basalt flakes, and then grafts 2-urea-based-4[1H] pyrimidone; the self-repairing prepolymer is a silicone-modified prepolymer grafted with composite phenylboronic acid ester; the composite phenylboronic acid ester is obtained by a thiol-ene click reaction of eugenol and 3-mercapto-1,2-propanediol to obtain double-hydroxyl eugenol, and then grafted with 2-urea-based-4[1H] pyrimidone under the action of boron-nitrogen coordination between 2-dimethylaminoethylamine and 3-aminophenylboronic acid to form phenylboronic acid ester with pH response by dehydration.

The application discloses a method for preparing trifluoroethylamine by continuous aminolysis using a micro-channel method, which comprises the following steps: (1) mixing trifluoro-chloroethane with organic solvent I to obtain an A-phase solution; mixing ammonia, a surfactant and organic solvent II to obtain a B-phase solution; (2) feeding the A-phase solution and the B-phase solution into a micro-channel reactor at a certain flow rate at the same time, and heating to 50-110 DEG C to perform aminolysis reaction to obtain trifluoroethylamine. The preparation method disclosed by the application can ensure high conversion rate of a substrate, high selectivity and high yield of a target product, and the preparation process condition is simple, time consumption is short, and TFEA fine products are prepared, so that industrial production is more convenient to realize.

The utility model discloses an energy-saving device capable of reducing the production cost of ethylamine, which belongs to the technical field of chemical production and comprises a bottom plate and a dehydrating tower, a liquid inlet pipe is fixedly mounted above the side wall of the dehydrating tower, and a steam inlet pipe is mounted on the side wall of the dehydrating tower in a communicated manner; a steam exhaust pipe is installed on the top face of the dehydrating tower in a communicating mode, a shielding cap is installed above the steam exhaust pipe, a circular pipe is installed on the lower portion of the interior of the steam exhaust pipe in a sealed mode, and a sealing valve is attached to the interior of the circular pipe in a sliding mode. A transverse rod is transversely and fixedly installed on the upper portion of the interior of the steam exhaust pipe, a threaded rod is installed on the transverse rod in a threaded penetrating mode, a pressing plate is rotatably installed at the bottom of the threaded rod, a push spring is fixedly installed at the bottom of the pressing plate, and the bottom of the push spring is fixedly connected with a sealing valve. Compared with the prior art, the device can effectively improve the heating efficiency of raw materials in ethyl amine production, and further saves energy in ethyl amine production.

The utility model discloses an automatic monoethylamine liquid preparation system, and relates to the technical field of monoethylamine liquid preparation. Comprising a monoethylamine liquid preparation tank, a concentration sensor is arranged in the monoethylamine liquid preparation tank, and a liquid level meter is arranged on the monoethylamine liquid preparation tank; the monoethylamine liquid preparation tank is connected with a desalted water outer pipe through a pipeline; a desalted water regulating valve and a desalted water stop valve are arranged on the pipeline; the bottom of the side wall of the monoethylamine liquid preparation tank is connected with the monoethylamine liquid preparation cooler through a pipeline, the monoethylamine liquid preparation cooler is connected with one interface of the static mixer through a pipeline, the static mixer is connected with the monoethylamine storage tank through a pipeline, and the pipeline is provided with the monoethylamine stop valve and the monoethylamine regulating valve; the bottom of the monoethylamine liquid preparation tank is connected to one interface of the static mixer through a circulating pipeline, and a temperature sensor is arranged at the joint of the circulating pipeline and the monoethylamine liquid preparation tank; the concentration sensor, the liquid level meter, the desalted water regulating valve, the desalted water stop valve, the monoethylamine stop valve, the monoethylamine regulating valve and the temperature sensor are electrically connected.

The invention discloses a method for determining the content of ethambutol hydrochloride based on a surface enhanced Raman spectrum technology, through enhancement of nano-silver particles, the intensity of a characteristic peak in a Raman spectrum is remarkably increased, the detection sensitivity is greatly improved, a coagulant is added to enable the nano-silver particles to be in a certain aggregation state, and the detection sensitivity is greatly improved. The characteristic peak in the Raman spectrum is further enhanced; compared with traditional high performance liquid chromatography (HPLC) detection, the method has the advantages that the analysis and detection time is greatly shortened, the detection operation is simplified, the use of an organic solvent is reduced, and the economic benefit is remarkably improved.