418 results about "Acetylation" patented technology

The invention discloses a sodium alginate embedded iron-carbon microcapsule material for repairing cadmium and arsenic polluted soil and a preparation method of the sodium alginate embedded iron-carbon microcapsule material, and belongs to the technical field of soil heavy metal pollution repairing materials. The material comprises straw biochar, high-iron steel slag powder, a sulfydryl acetylated chitosan-iron monatomic cluster compound, a boron-doped graphitized carbon coated cobalt ferrite nanosheet, sodium alginate, calcium chloride and sodium carbonate. Wherein the sulfydryl acetylated chitosan is prepared by reacting chitosan with sulfydryl acetic anhydride, dialyzing and drying, and performing solvothermal reaction with ferric nitrate under high pressure. The preparation method comprises the following steps: pyrolyzing and drying the straw biochar, reacting the high-iron steel slag with sulfuric acid, adding the biochar, adjusting the pH value, adding sodium carbonate, mixing to obtain an iron-carbon-based passivation material, mixing with two modified compounds, mixing with a sodium alginate solution, dropwise adding a calcium chloride solution, and stirring and curing. The material can be applied to remediation of cadmium and arsenic polluted soil.

The invention discloses a lignin-based epoxy anticorrosive paint and a preparation method thereof. The anticorrosive paint is prepared by mixing a lignin-based epoxy anticorrosive paint component, a lignin-based phenolic amine curing agent and a diluent. According to the lignin-based epoxy anticorrosive paint disclosed by the invention, on one hand, a lignin epoxy resin acetylation modification method based on lipase is introduced, and the content of hydrophilic groups is reduced, so that formation of a compact lignin cross-linked network structure is promoted, and the barrier ability, heat resistance and aging resistance of an anticorrosive coating on a chemical medium are improved on the resin level; on the other hand, lignin and furfural are respectively used for partially replacing phenol and paraformaldehyde to prepare a lignin-based phenolic aldehyde amine curing agent with high chemical inertness, so that the protection effect of a coating in an extreme corrosion environment and the adhesive force to a metal base material are improved on the curing agent level. The lignin-based epoxy anticorrosive paint prepared by the invention has good corrosion resistance, aging resistance, thixotropy and adhesive force.

The invention discloses a peracetylated polysaccharide derivative mixing accelerator as well as a preparation method and application thereof, and relates to the technical field of polysaccharide derivatives. Alkyl polyglucoside and glycidyl ether are subjected to etherification reaction to obtain polysaccharide derivatives; and adding acetic anhydride and an organic weak base catalyst into the polysaccharide derivative, and carrying out esterification reaction to obtain the peracetylated polysaccharide derivative. The obtained peracetylated polysaccharide derivative can be used for reducing the minimum miscible pressure of CO2 in an offshore oilfield. The polysaccharide derivative provided by the invention is simple in synthesis process, and the molecular activity of the polysaccharide derivative can be regulated and controlled by changing the number of carbon dioxide-philic groups and the length of oleophylic unsaturated hydrocarbon chains, so that the polysaccharide derivative can be used in the CO2 oil displacement process of oilfield exploitation, and the minimum miscible pressure in the CO2 oil displacement process is effectively reduced.

The invention belongs to the technical field of biomass materials and environment-friendly adhesives, and relates to a biomass adhesive, in particular to a preparation method of a biomass environment-friendly adhesive based on longan shells, which comprises the following steps: firstly, cleaning, drying, crushing and screening the longan shells for pretreatment, and then carrying out alkalization and acetylation chemical modification to obtain the biomass environment-friendly adhesive based on the longan shells. And finally, compounding with gelatinized starch, a chitosan acetic acid solution and citric acid, and adjusting the viscosity to obtain the adhesive. The waste longan shells are used as raw materials, agricultural waste recycling is achieved, the product is free of formaldehyde release and biodegradable, and the viscosity of the prepared adhesive is 1000-2000 mPa.s at the temperature of 25 DEG C and is measured through a rotary viscometer; the wood-wood bonding strength is larger than or equal to 2.5 MPa, the 24-hour water absorption rate is smaller than or equal to 25%, the problems that a traditional biomass adhesive is short in performance and low in cost, special equipment is not needed for preparation are solved, the adhesive is suitable for the industrial fields of artificial board manufacturing, furniture manufacturing and the like, and environment-friendly transformation of the adhesive industry is promoted.

The invention relates to the technical field of fibers, in particular to a controlled-release anti-aging polypropylene fiber and a preparation method thereof. The fiber is prepared from polypropylene homopolymer resin, a reaction type interface layer master batch and a controlled release anti-aging master batch, the reactive interface layer master batch is formed by reacting and extruding maleic anhydride modified polypropylene and 3-aminopropyl terminated polydimethylsiloxane, so that the interface compatibility is enhanced; the controlled-release anti-aging master batch contains hydroxyl and peracetylated cyclodextrin grafted siloxane carriers, and an ultraviolet absorbent, a light stabilizer and an antioxidant are included, so that the controlled release of an anti-aging agent is realized. The preparation method comprises the steps of master batch preparation, final mixing granulation, melt spinning and drafting setting. The fiber strength is remarkably improved, the boiling water shrinkage rate is reduced, the strength retention rate after ultraviolet aging reaches 93% or above, the yellow index change is small, and the outdoor service life is prolonged.

The invention discloses a modified bamboo fiber reinforced polypropylene composite material and a preparation method thereof, and belongs to the field of polypropylene composite materials, the modified bamboo fiber reinforced polypropylene composite material is characterized by comprising the following raw materials by mass: 1-10 parts of modified bamboo fiber, 80-90 parts of polypropylene, and 1-5 parts of a compatilizer. The modified bamboo fiber is prepared by modifying the surface of bamboo fiber by using acetic anhydride as an acetylation reagent and concentrated sulfuric acid and glacial acetic acid as a solvent system. Through acetylation modification of the bamboo fiber, the surface hydrophobic effect of the bamboo fiber is greatly improved, the bamboo fiber adapts to a polypropylene polymer non-polar material, and the interfacial compatibility between the bamboo fiber and polypropylene is improved. Fine fibers can be separated from the modified bamboo fibers through two screw extrusion processes under the shearing action of the screws and are uniformly dispersed in a polypropylene matrix, the fine fibers have the effect of a heterogeneous nucleating agent on polypropylene, the reinforcing effect of the bamboo fibers on the polypropylene is improved, and the composite material is endowed with more excellent mechanical performance and thermal stability.

The invention relates to the technical field of high polymer materials, in particular to a degradable PHA tableware material and a preparation method thereof. The degradable PHA tableware material overcomes the problem that the degradable PHA tableware material is poor in mechanical property and antibacterial property. The preparation method comprises the following steps: drying polyhydroxyalkanoate, poly (butylene succinate), acetylated lignin, nano-zinc oxide, chitosan oligosaccharide and hexagonal boron nitride, carrying out melt extrusion on the dried materials, maleic anhydride grafted PHA, acetyl tributyl citrate and cinnamyl aldehyde in a double-screw extruder, carrying out injection molding, and carrying out plasma treatment activation. Polyurethane antibacterial slurry containing silver-loaded zeolite is sprayed, the tableware material with the body-surface synergistic enhancement function is finally obtained, and the impact strength, rigidity and antibacterial rate of the material are improved.

The invention relates to the technical field of biological medicines, and discloses a PD-L1 K263 acetylation modified antibody, which is prepared from an immunogen containing a sequence as shown in SEQ ID NO.1. The PD-L1 K263 acetylation modified antibody is a PD-L1 K263 acetylation modified antibody. The invention also discloses a preparation method of the PD-L1 K263 acetylation modified antibody. The preparation method comprises the following steps: designing and synthesizing a polypeptide antigen, preparing an immunogen, immunizing animals, purifying the antibody and evaluating serum titer. The antibody provided by the invention can accurately recognize and combine with the PD-L1 protein subjected to K263 acetylation modification in the breast cancer, provides a specific tool for qualitative and quantitative detection of K263Ac-PD-L1 in the breast cancer, and provides a reliable molecular marker detection means for evaluating the curative effect of anti-PD-1 / PD-L1 immunotherapy; therefore, a biological preparation with specificity and practicability and a technical support are provided for accurate diagnosis, targeted therapy and curative effect monitoring of breast cancer.

The present invention relates to matrix-forming cross-linked carboxyalkyl chitosan, to compositions comprising same, to a process for the preparation thereof and to various uses thereof, in particular in therapeutic, rheumatology, ophthalmology, cosmetic medicine, plastic surgery, open surgery, dermatology, gynecology or cosmetic fields. In particular, the invention relates to a substrate comprising at least one carboxyalkyl chitosan having glucosamine units, N-acetylglucosamine units and glucosamine units substituted with a carboxyalkyl group, expressed in the number of moles of N-acetyl groups relative to the number of moles of total glucosamine units, the acetylation degree of the carboxyalkyl chitosan is 40%-80%, and the carboxyalkyl chitosan is crosslinked through covalent bonds between carboxyalkyl chitosan chains.

The invention discloses a chemical-enzymatic coupling synthesis method of oseltamivir phosphate, which comprises the following steps: by taking monasic acid OS-01 as a substrate, sequentially carrying out S1 esterification, S2 ketalation, S3 selective ring opening, S4 TEMPO oxidation, S5 primary transaminase reaction, S6 acetylation, S7 secondary transaminase reaction and S8 phosphorylation reaction to obtain the final product oseltamivir phosphate OS-09. According to the method, the step of sodium azide required by a traditional route is avoided, the production safety and the industrialization possibility are enhanced, two different transaminases are used for respectively constructing different chiral centers, the steps of protecting groups and deprotecting groups on the traditional route are not needed, the overall route is short, the used chemical reagents are few, the yield is high, and the method is suitable for industrial production. The industrial requirements of environmental protection and low cost are met.

The application discloses a synthesis method of 2'-OMe adenosine, comprising the following steps: S1. dissolving adenosine in DMF, and reacting with a methylation reagent in the presence of a base to obtain a mixture of 2'-OMe adenosine and 3'-OMe adenosine; S2. reacting the mixture of 2'-OMe adenosine and 3'-OMe adenosine with acetic anhydride in a solvent to obtain an acetylated mixture; S3. deacetylating the acetylated mixture under the action of ammonia, and crystallizing to obtain 2'-OMe adenosine; the application uses cheap and easily available raw materials and a safe alkylating reagent, synthesizes 2'-OMe adenosine through a shorter route, avoids column chromatography operation, and provides a new synthesis method of 2'-OMe adenosine which is easy to process.

The present disclosure relates to compositions for increasing acetylated alpha-tubulin levels in peripheral neuronal cells. The present disclosure also relates to the use of tubulin deacetylase inhibitors, or activators of tubulin acetylation for increasing acetylated tubulin levels in the cells. The present disclosure also relates to methods for assessing risk of developing peripheral neuropathy by assessing the levels of acetylated alpha-tubulin. The present disclosure further relates to methods for treating a subject suffering from a peripheral neuropathy using the compositions described herein.

The application belongs to the technical field of organic synthesis, and particularly relates to a preparation method of alpha soludex. The preparation method takes 11-ketoprogesterone as raw material, firstly acetylates the ketone group at the 3 position, then obtains 3beta-hydroxyl through a composite biological enzyme method, and finally obtains alpha soludex through hydrogenation and translocation reaction. The composite biological enzyme method is used to obtain 3beta-hydroxyl, has good specificity, mild reaction conditions, does not need special equipment, and has high conversion efficiency. The preparation method of the application is easy to purify the reaction products of each step, the total mass yield of the final alpha soludex product is greater than 85%, and the HPLC purity is greater than 99.5%. The preparation method of the application has low cost and is suitable for industrial large-scale production.

The application belongs to the technical field of biology and particularly relates to a kind of biomimetic enzyme and its application in degrading aflatoxin.The raw material of the biomimetic enzyme includes polypeptide and divalent copper ion, the sequence of the polypeptide is shown in SEQ ID No.1, specifically: Ac-HCHLKLKLKL-CONH2, the N terminal of the polypeptide is acetylated, and the C terminal is amidated.The biomimetic enzyme is constructed by sequencing design and metal coordination to construct an active site, is stable in catalyzing AFB1 rupture in wide pH and temperature, has the advantages of good tolerance, high catalytic efficiency, and has potential application advantages in the application in grain and feed purification.

This invention relates to a compound containing trifluoromethyloxadiazole and a spirocyclic structure, or a pesticide-acceptable salt, hydrate, or solvate thereof, characterized in that the structure of the compound containing trifluoromethyloxadiazole and a spirocyclic structure is shown in general formula I. Compared with the prior art, the compound provided by this invention can be used to prepare histone deacetylase inhibitors, effectively inhibiting the growth and reproduction of various rust fungal spores, with effects comparable to fluopyram.

The invention relates to the technical field of high polymer materials and the technical field of polyvinyl alcohol, in particular to acetoacetylated polyvinyl alcohol modified resin as well as a preparation method and application of the acetoacetylated polyvinyl alcohol modified resin. And then the acetoacetylated polyvinyl alcohol modified resin is subjected to acid treatment by using an aqueous solution of a non-oxidizing acid to reduce the chroma of the acetoacetylated polyvinyl alcohol modified resin, so that the problems of poor solubility and yellow color of the product in the existing method are fundamentally solved, and the acetoacetylation degree and structural stability of the product are ensured at the same time.

The application discloses a histone deacetylase inhibitor and application thereof. Specifically, the application relates to a compound shown in a general formula (I), a pharmaceutically acceptable salt of the compound, and a preparation method and application of the compound. The compound has a good inhibiting effect on histone deacetylase, and can be used for treating tumors and related diseases.

The invention belongs to the technical field of vinasse recycling, and discloses a vinasse / EVA composite foaming packaging material and a preparation method thereof. The preparation method comprises the following steps: carrying out pretreatment and surface modification on vinasse to obtain hydrophobicity-enhanced modified vinasse powder; uniformly mixing EVA, the modified vinasse powder, a foaming agent, a cross-linking agent, a lubricating agent and an activating agent to obtain a mixture; and carrying out mould pressing and heating on the mixture to foam and crosslink the mixture, and cooling to obtain the composite foam material. Through the synergistic effect of'alkali liquor-hydrogen peroxide combined treatment + acetylation modification ', the content of polar hydroxyl on the surface of the vinasse fiber is effectively reduced, and the vinasse fiber is changed from hydrophilicity to hydrophobicity. The modified vinasse powder and a non-polar EVA matrix follow the principle of similar dissolves, and the interface bonding force is greatly enhanced, so that the mechanical properties of the composite material, such as tensile strength and elongation at break, are remarkably improved.

The invention belongs to the technical field of biology, and particularly relates to acetylated raffinose and application thereof. According to the invention, acetylation modification is carried out on raffinose by using an acetylation reagent to obtain acetylated raffinose, the acetylated raffinose can significantly improve the scavenging ability and total antioxidant ability of raffinose on DPPH free radicals, and the scavenging ability on hydroxyl free radicals and the reduction ability on iron ions are also improved to a certain extent. The acetylated raffinose provided by the invention has potential application value in development of functional foods and antioxidants.

The application discloses a method for preparing 3-methoxy-3-methyl-1-butyl acetate, and belongs to the technical field of organic compound synthesis. The method comprises the following steps: taking 3-methoxy-3-methyl-1-butanol as raw material, and respectively adopting acetic acid, acetic anhydride and acetyl chloride as acetylation reagents, and adding a catalyst or an acid-binding agent to perform acetylation reaction, so as to obtain 3-methoxy-3-methyl-1-butyl acetate. The application provides a synthesis method for 3-methoxy-3-methyl-1-butyl acetate, takes 3-methoxy-3-methyl-1-butanol as raw material, respectively adopts acetic acid, acetic anhydride and acetyl chloride as acetylation reagents, adds a catalyst or an acid-binding agent to perform acetylation reaction, and obtains 3-methoxy-3-methyl-1-butyl acetate. In view of the defect that there is no acetylation synthesis process suitable for the target product in the prior art, the related technical blank is filled.

The application provides a composite iron phosphate and a preparation method and application thereof, and the preparation method comprises the following steps: (1) mixing nanocellulose, glacial acetic acid, acetic anhydride, perchloric acid and an organic solvent to obtain acetylated nanocellulose through reaction; (2) mixing nanocellulose, TEMPO and sodium bromide with water, adding sodium hypochlorite solution to obtain oxidized nanocellulose through reaction; (3) mixing the oxidized nanocellulose and the acetylated nanocellulose with an acidic aqueous solution, then mixing with an oily solvent to obtain a water-in-oil emulsion; (4) mixing an iron source, a phosphorus source and the water-in-oil emulsion, and then obtaining the composite iron phosphate through sintering treatment after reaction. The application utilizes the different hydrophilic / hydrophobic difference of acetylated and oxidized nanocellulose to induce the generation of a spherical shell-shaped iron phosphate filled with rod-shaped structures, the nanocellulose forms carbon in situ after high-temperature calcination, and the uniform distribution of the carbon layer is realized, and the conductivity is further improved.

The invention belongs to the field of microbial fermentation and the technical field of daily chemicals, and particularly relates to deacetylated sophorolipid as well as a preparation method and application thereof. By using cheap culture medium components and screening out saccharomycetes with high yield of lactone type sophorolipid, the problem that the production cost of the sophorolipid is too high is effectively solved, and the application of the sophorolipid in various fields is promoted; through the step of carrying out enzymolysis on a fermentation substrate in advance, the problems of long single fermentation period, low thallus utilization rate, high energy consumption and high cost of traditional saccharomycetes are solved. A multi-round fermentation circulation system is designed, and bacteria liquid is settled and recycled and then inoculated and fermented, so that thalli are efficiently and repeatedly utilized, the unit yield is increased, the fermentation period is shortened, and the production cost is effectively controlled. The structure is adjusted through a resin modification technology, a final product mainly comprises acetylated sophorolipid, and compared with acetylated sophorolipid and deacetylated sophorolipid, the sophorolipid has better foam stability and sensitive skin repairing effect and is suitable for the application fields of cosmetics, washing care and the like.

The invention discloses an in-situ acetylation-co-crystallization method and application of the in-situ acetylation-co-crystallization method in organic molecular structure determination, and the in-situ acetylation-co-crystallization method comprises the following steps: synthesizing a cyclic trinuclear silver (I) complex as a crystallization partner, and carrying out an in-situ acetylation reaction in an organic molecular sample, after the reaction is completed, adding a crystallization partner for co-crystallization; the application of the in-situ acetylation-co-crystallization method in the determination of the organic molecular structure comprises the following steps: preparing a co-crystal from an organic molecule to be detected through the in-situ acetylation-co-crystallization method, collecting crystallographic data of the co-crystal, and analyzing to obtain a crystal structure of an acetylation product of the organic molecule to be detected; and determining the chemical structure and the spatial configuration of the to-be-detected organic molecule according to the crystal structure of the to-be-detected organic molecule acetylation product. The method can be used for structure determination of a series of acetylated organic molecules such as alcohols, phenols, amines and the like.

The application discloses a nitrogen acetylated carbazole alkaloid, and the structure is selected from one of the following structures: The application discloses a nitrogen acetylated carbazole alkaloid produced by fermentation of streptomyces J1074, and provides a biosynthetic preparation method, which is more green and environmental protection, and cost reduction compared with a chemical synthesis method; the compound ATC-A provided by the application shows significant antithrombotic activity in a thrombotic zebrafish model, which may be related to down-regulation of gene expression related to platelet activation and blood coagulation cascade, and has important development prospect and clinical application value.

The present application relates to the technical field of food processing, and particularly relates to acetylated carrageenan with anti-inflammatory activity and a preparation method and application thereof, the preparation method comprising the following steps: step 1: carrageenan acidolysis, obtaining carrageenan powder with different molecular weights, and adding the carrageenan powder into formamide to obtain a mixed solution; step 2: placing the mixed solution in a reaction environment with a temperature of 40-60 DEG C to react; step 3: obtaining an acetylated carrageenan solution by reaction; step 4: adding anhydrous ethanol to precipitate, centrifuging to obtain the precipitate, resolubilizing with water, using a 500Da dialysis bag to dialyze with distilled water, and freeze-drying to obtain acetylated carrageenan. The present application has the beneficial effect that the preparation method of the acetylated carrageenan obtained by the above technical solution of the present application acetylates and modifies specific low-molecular-weight carrageenan, has the effects of reducing inflammation of low-molecular-weight carrageenan, improving the degree of acetyl substitution, promoting the biological activity of carrageenan and many other advantages, and can be produced industrially.

The application belongs to the technical field of pharmaceutical chemistry synthesis, and specifically discloses a preparation method of oseltamivir and a phosphate thereof and an intermediate thereof, which comprises the following steps: (1) a compound of formula VII is reacted with VIII under the action of a base in a solvent to obtain an intermediate of formula VI, and then the intermediate of formula VI is reacted under the action of a strong base at high temperature to obtain formula V; (2) formula V is subjected to ring-opening reaction with tert-butylamine in a solvent under the catalysis of a Lewis acid to obtain formula IV; (3) formula IV is reacted with an acetylating agent in a solvent under the action of a base to obtain formula III; (4) formula III is reacted under the action of an acid at a certain temperature to obtain formula II; and (5) formula II is subjected to salt formation with phosphoric acid in a solvent to obtain oseltamivir. The preparation method has the characteristics of simple operation, low cost, high yield, high optical purity of the product, stable process and the like, and is suitable for industrial production.

The application belongs to the technical field of starch chemical modification, and particularly relates to a preparation method of acetylated distarch phosphate. The method comprises the following steps: mixing starch with a deep eutectic solvent composed of choline chloride, glycerol and a small amount of water, adding a phosphate crosslinking agent and a delayed-release alkalizing agent for crosslinking reaction after pH adjustment, performing acetylation reaction by adding acetic anhydride or vinyl acetate after cleaning by alcohol solvent replacement, and finally obtaining the product through neutralization, washing, dehydration and drying. The process utilizes the deep eutectic solvent to control water activity and particle structure, and combines the slow-release alkali source to maintain a stable reaction environment, so that the crosslinking and acetylation are uniformly carried out, and the side reactions and residual salt load are effectively reduced. The obtained acetylated distarch phosphate has stable substitution degree, uniform particle structure and excellent performance in freeze-thaw stability, and is suitable for multiple fields such as papermaking, textile and oil field additives.

The invention relates to a preparation method of acetylated distarch phosphate with high transparency, and belongs to the technical field of starch deep processing. The method comprises the following steps: by taking waxy corn starch as a raw material, dispersing the waxy corn starch into starch milk, and carrying out ultrasonic pretreatment; then sequentially carrying out acetylation and cross-linking reaction under a step-by-step optimization condition: firstly, taking acetic anhydride as a reagent, carrying out reaction at the pH value of 8.0-9.0 and the temperature of 20-35 DEG C, neutralizing until the pH value is 6.0-7.0, then taking sodium trimetaphosphate as a cross-linking reagent, adding sodium chloride as an accelerant, and carrying out reaction at the pH value of 10.0-11.0 and the temperature of 35-50 DEG C; and finally, neutralizing, washing with a 70-90% ethanol water solution, and drying to obtain the product. The product disclosed by the invention is excellent in transparency and good in freeze-thaw stability, and can be efficiently applied to preparation of transparent gel foods, frozen desserts and neutral transparent beverages.

The invention discloses an antibody for specifically recognizing 1147th acetylation of ribosome biosynthetic factor 1 protein as well as a preparation method and application of the antibody. According to the protein sequence and the modification type of the ribosome biosynthetic factor 1, two modified antigen polypeptides A and B are designed, and through detection, the antibody obtained by immunizing animals with the two polypeptides has high specificity and affinity, can accurately recognize the acetylation modification form of the 1147th site of BMS1, and avoids recognition of an unmodified form or other modification sites. The antibody is suitable for various immunological detection methods, is high in repeatability and low in background, has mass production potential, can realize industrialization, not only can be used for evaluating the cis-platinum drug resistance condition in esophageal cancer treatment, but also can be used for various scenes such as basic research, disease mechanism analysis, biomarker development and drug target screening, and is wide in application range.

The invention belongs to the technical field of medicines, and particularly relates to acetylated hawthorn polysaccharide as well as a preparation method and application thereof. The preparation method of the acetylated hawthorn polysaccharide comprises the following steps: adding fresh hawthorn fruits into a deep-eutectic solvent for homogenization, and extracting by adopting a physical method to obtain an extracting solution; carrying out alcohol precipitation and centrifugation on the extracting solution to prepare crude polysaccharide; and adding water into the crude polysaccharide, redissolving, deproteinizing, concentrating, dialyzing and freeze-drying to obtain the acetylated hawthorn polysaccharide. The method utilizes a physical method to cooperate with deep eutectic solvent extraction, is green and pollution-free, can realize efficient preparation and effective separation of acetylated hawthorn polysaccharide, has high acetylation degree, has in-vitro and in-vivo intestinal mitochondrial homeostasis regulation activity, has no toxic or side effect, is suitable for people with intestinal mitochondrial related diseases, and also has the functions of improving intestinal mitochondrial homeostasis regulation. And the composition is also suitable for preventing intestinal diseases of normal people.