321 results about "Amidogen" patented technology

The invention relates to the technical field of oil exploitation, and discloses a compound containing an amide group as well as a preparation method and application thereof. The compound containing the amide group has a structure as shown in a formula (1). The polymer obtained by polymerizing the compound can improve the water-drive recovery efficiency of conventional oil reservoirs and common heavy oil reservoirs. # imgabs0 #

The invention belongs to the technical field of organic matter preparation, and discloses an amide-containing isoxazoline derivative as well as a preparation method and application thereof. According to the invention, chemical modification and molecular design are carried out on the compound with an isoxazoline structure, and a substituent group is introduced to N of an amide group, so that a series of efficient compounds which can be used for killing insects or mites in agriculture or forestry and have excellent activity are obtained, and particularly, the compounds have very good biological activity on lepidoptera, hemiptera and other pests. When being used at an extremely low concentration, the compound disclosed by the invention also shows an excellent control effect on various pests or pest mites, has insecticidal or acaricidal activity in each stage (such as eggs, larvae (nymphs), pupae and adults) of the life cycle of the pests or pest mites, and has an excellent control effect on the pests or pest mites which have drug resistance to traditional insecticides or acaricides. And the composition also shows excellent control activity.

A photobase generator includes a compound including: first skeletons represented by the following formula (a); and a second skeleton including nitrogen atoms bonding to bonding positions of the first skeletons to form amide groups, wherein, in a molecule, a number of the first skeletons is two or more, a number of the nitrogen atoms, configuring the amide groups, in the second skeleton is the same as the number of the first skeletons, and at least one of the nitrogen atoms configuring the amide groups is converted into a nitrogen atom configuring a secondary amine or a tertiary amine by light irradiation. In the formula (a), G is a divalent aromatic group, and * represents the bonding position with the nitrogen atom.

The invention relates to an epoxy hardener as well as a preparation method and application thereof. The epoxy hardener is prepared from ring-containing anhydride A, diamine B with a long polyether chain and active diamine D through reaction. The epoxy curing agent is endowed with relatively high rigidity by the annular structure of the epoxy curing agent; two amide groups are close to each other and are located on a V-shaped tooth-shaped structure, two close chains contain active hydrogen and nitrogen atoms which can react with the same epoxy resin molecule to form a new cross-linked ring structure, and a filler in the epoxy resin composition can be embedded into the new ring structure to improve the rigidity of the epoxy resin composition; the long polyether chain endows the epoxy curing agent with relatively high viscosity and toughness, and the impact strength of a cured product is improved; the active diaminobutyl improves the reaction rate of the epoxy curing agent, so that the epoxy resin composition has shorter surface drying time.

The invention relates to the field of water treatment, in particular to a composite material with polyfunctional groups and a preparation method and application thereof.The composite material with the polyfunctional groups contains at least two groups including carboxyl, amino, amido and hydroxyl and at least one group including sulfo and nitro; the composite material contains a cross-linked compound of a polymer I and a polymer II, and the polymer I is a carbon chain polymer and contains at least one group including a sulfonic acid group and a nitro group; and the polymer II is at least one of chitosan and a derivative thereof, and chitin and a derivative thereof. The composite material with multiple functional groups is preferably a composite fiber, has a synergistic adsorption effect of multiple functional groups, can effectively adsorb a complex heavy metal ion system in a water body, and is a heavy metal ion adsorbent which is high in adsorption efficiency, large in adsorption quantity and wide in applicable temperature range.

A resist underlayer film, which, while exhibiting excellent resistance to a resist developer which is a resist solvent or an alkaline aqueous solution, exhibits removability, and preferably solubility, only in wet etching chemicals. This composition for forming a resist underlayer film contains a solvent, a heterocyclic compound having a dicyanostyryl group, a cyclic compound including an amide group, for example, and the reaction product of a heterocyclic compound precursor having an epoxy group and an active proton compound, for example.

The invention relates to an acridine sulfonamide carboxylic acid derivative as well as a preparation method and application thereof, and the preparation method comprises the following steps: in an alkaline environment, acridine sulfonamide and amino acid or an amino acid derivative are subjected to amidation reaction in an organic solvent, and the acridine sulfonamide carboxylic acid derivative is obtained after purification; wherein the acridine sulfonamide carboxylic acid derivative has two acridine sulfonamide-like groups, and the two acridine sulfonamide-like groups are connected through the amino acid or the amino acid derivative. The yield of the preparation method exceeds 70%, and the luminous efficiency of the prepared acridine sulfonamide carboxylic acid derivative is higher and is about two times that of acridine sulfonamide NSP-SA-NHS.

The invention relates to the technical field of oilfield exploitation, and discloses a preparation method of a drag reducer for a high-salt-resistance fracturing fluid. According to the preparation method, methacrylamide, acrylic acid, N-allyl imidazole, naphthyl modified sulfo modified morpholine derivatives and quaternary ammonium salt modified triazinyl pyrrolidone are polymerized in water, washed and dried, and the drag reducer for the high-salt-resistance fracturing fluid is obtained. The sulfonate radical enhances the solubility of the polymer, and enables the molecular chain skeleton of the polymer to carry more negative charges, so that the molecular chain is not easy to curl, and the salt resistance and shear resistance are improved; a hydrophobic association structure formed by introducing a long carbon chain and naphthyl on a polymer molecular chain is beneficial to association among molecules under the action of external salt, so that the salt-resistant and shear-resistant effects are enhanced; a steric effect generated by a pyrrole group, a morpholine group and a triazine group can limit hydrolysis of a primary amide group of a main chain, so that the salt resistance is improved; the quaternary ammonium salt group can increase the rigidity of a molecular chain, so that the anti-shearing performance is improved.

The invention discloses a preparation method, an intermediate and application of menochromone. The preparation method comprises the following steps: reacting 4-bromopyrrole-2-carboxylic acid with propargylamine to generate 4-bromo-N-propynyl pyrrole-2-formamide; the preparation method comprises the following steps: reacting 4-bromo-N-propinyl pyrrole-2-formamide with pinacol borane to generate a mixture; reacting the mixture with 2-(t-butyloxycarboryl amino)-5-iodo-1H-imidazole to generate (E)-(5-(3-(4-bromo-1H-pyrrole-2-formamido) prop-1-ene-1-yl)-1H-imidazole-2-yl) tert-butyl carbamate, and reacting the (E)-(5-(3-(4-bromo-1H-pyrrole-2-formamido) prop-1-ene-1-yl)-1H-imidazole-2-yl) tert-butyl carbamate with the tert-butyl carbamate; and reacting the (E)-(5-(3-(4-bromo-1H-pyrrole-2-formamido) prop-1-ene-1-yl)-1H-imidazole-2-yl) tert-butyl carbamate with a dioxane hydrochloride solution, so as to generate the menochromone. The invention provides a preparation method of menosin, which is short in synthetic route, simple and convenient to operate, high in product yield and suitable for industrial production.

The invention discloses amino-terminated hyperbranched polyamide acid as well as a preparation method and application thereof. The amino-terminated hyperbranched polyamide acid is formed by polymerizing an aromatic anhydride monomer, an aromatic triamine monomer and an aromatic diamine monomer; the mole numbers of the aromatic anhydride monomer, the aromatic triamine monomer and the aromatic diamine monomer are a, b and c respectively, a: (b + c) = 1: 1-1: 1.5, and the proportion of b to c is any proportion. The amino-terminated hyperbranched polyamide acid disclosed by the invention not only has abundant terminal amino groups, but also contains a large number of polar groups such as ether bonds, imidazole rings, amide groups and carboxyl groups in molecular chains. Therefore, a stable water-based colloid emulsion can be formed in the presence of water and a small amount of organic solvent, other auxiliaries are not needed, and the interface performance and the mechanical performance of the composite material can be greatly improved.

The invention discloses polyhedral oligomeric silsesquioxane containing an amido bond and a hindered phenol functional group as well as a preparation method and application of the polyhedral oligomeric silsesquioxane. The structural formula of the polyhedral oligomeric silsesquioxane is one or more of the following formulas I-III, r1 and R2 are independently selected from at least one of hydrogen, alkyl, alkoxy, hydroxyalkyl, cycloalkyl, cycloalkyl alkyl, aryl, aralkyl, heterocyclic radical, heterocyclic radical alkyl, carboxyl, ester group, acylamino, amino, amido, halogen, nitro, cyano, oxycarbonyl and aminocarbonyl; and R3 and R4 are independently selected from alkylene with 0 to 20 carbons. The polyhedral oligomeric silsesquioxane containing the amido bond and the hindered phenol functional group prepared by the preparation method disclosed by the invention is high in hindered phenol functional group content and small in size, long-term and efficient protection can be realized under a low addition amount, and the thermo-oxidative aging resistance of a polymer is effectively improved.

An amido group-containing monomer composition contains 80.00 to 99.99 mass % of an amido group-containing monomer (a) of the following formula (1) and 0.01 to 20.00 mass % of a metal chelate complex (b) having carbonyl group as a ligand:wherein R1 represents a hydrogen atom or a methyl group, R2 represents a hydrocarbon group having a carbon number of 1 to 6, R3 represents a hydrocarbon group having a carbon number of 1 to 23, and R4 represents hydrogen or a methyl group.

The purpose of the present invention is to provide an industrially preferred method for producing a p-toluenesulfonate of 7-(2,3-difluoro-4-(2-((2-methoxyethyl)(methyl)amino)ethoxy)benzyl)-10-hydroxy-6-methyl-N-(4-methyl-2-(6-methylpyrimidin-4-yl)phenyl)-8-oxo-6,7-diazaspiro[4,5]dec-9-ene-9-carboxamide, which enables a target product to be obtained more inexpensively and easily as compared to conventional methods.The present invention has attained a method which enables a target product to be efficiently obtained by a step of preparing wet powder of a p-toluenesulfonate of 7-(2,3-difluoro-4-(2-((2-methoxyethyl)(methyl)amino)ethoxy)benzyl)-10-hydroxy-6-methyl-N-(4-methyl-2-(6-methylpyrimidin-4-yl)phenyl)-8-oxo-6,7- diazaspiro[4,5]dec-9-ene-9-carboxamide, and a step of drying the wet powder.

The invention discloses a compound and application thereof, and belongs to the technical field of medicinal chemistry. The structure of the compound is shown as a formula I. In the formula I, A ring is selected from C6-C12 aryl or C5-C6 cycloalkyl; r1 and R2 are independently selected from one or more of hydrogen, C1-C10 straight chain or branched chain alkyl, C3-C6 naphthenic base, C1-C10 alkoxy, substituted C1-C10 straight chain or branched chain alkyl, substituted C3-C6 naphthenic base, substituted C1-C10 alkoxy, amino, halogen, nitrile group and nitryl; m and n respectively represent the numbers of R1 and R2, m + n = 5, and m > = 1; l is selected from a thioformamido group, a formamido group, a sulfonyl group, a sulfonamido group, a sulfonylurea group, an ester group or a carbonyl group. The compound is unique and novel in structure, and has relatively strong inhibitory activity and excellent analgesic effect as a TRPV1 inhibitor. # imgabs0 #

The invention deals with a composition comprising a liquid carrier, which is liquid at a temperature of 23 °C, a block co-polymer comprising at least one block (A) wherein block (A) comprises at least one amide group and at least one block (B) having no amide groups, dissolved in the liquid carrier, wherein block (A) does not contain aromatic groups, and an ionic compound, wherein the ionic compound comprises at least one of CaCl2, MgCl2, SrCl2, ZnCl2, carbamimidoylazanium chloride, NaSCN, NaBr, dissolved in the liquid carrier.

One embodiment of the nonlinear light-absorbing material disclosed herein comprises a compound represented by the following formula (1) as its main component. In formula (1), R 1 ~R 10 Each group can be a hydrogen atom, halogen atom, saturated hydrocarbon group, haloalkyl group, unsaturated hydrocarbon group, hydroxyl group, carboxyl group, alkoxycarbonyl group, aldehyde group, acyl group, amide group, nitrile group, alkoxy group, acyloxy group, thiol group, alkylthio group, sulfonic acid group, acylthio group, alkylsulfonyl group, sulfonamide group, primary amino group, secondary amino group, tertiary amino group, or nitro group.

The application discloses a platinum complex with controllable activity and a preparation method and application thereof, which is formed by coordination of vinyl siloxane, modified ligand and chloroplatinic acid; the modified ligand is prepared by reaction of maleic anhydride, allylamine and hydroxymethyl dimethyl phosphite. The application introduces amide groups and phosphite groups into the molecular chain of maleic anhydride, uses the groups as coordination compounds to coordinate with vinyl siloxane and platinum, and can improve the normal-temperature storage stability of the platinum catalyst while still keeping high catalytic activity of the platinum catalyst on the hydrosilylation reaction; when the platinum complex is used for catalyzing preparation of addition-type liquid silicone rubber, no inhibitor needs to be added, and the silicone rubber has good mechanical properties.

The application discloses a kind of high selectivity nanofiltration composite membrane and preparation method thereof, belong to nanofiltration membrane related technical field.The application is in the form of in-situ polymerization with anhydride, ester group, amide group on membrane surface, the degree of hydrolysis of polyamide membrane is controlled by the cleaning of post-processing solution, to control the charge density of membrane surface, to improve or reduce the permeability of monovalent ion;By controlling the ratio of trimesoyl chloride and diacyl chloride monomer, the size of pore structure can be adjusted, further improving the permeability of monovalent salt;By adjusting the amount of hydrophilic pore-forming agent to improve the hydrophilic performance of ultrafiltration base film, the flux and monovalent salt permeability of nanofiltration composite membrane are improved.The high selectivity nanofiltration composite membrane prepared by the application has excellent divalent salt ion removal rate, lower monovalent salt removal rate, and higher water flux, suitable for industrial production.

The invention relates to the technical field of electrochemistry, in particular to a method for improving the charge-discharge performance of a tin-air battery. A trace amount of urea is added into the electrolyte and the carbon cloth substrate is pretreated, so that amide groups (C = O and-NH) in urea molecules can interact with the carbon cloth substrate, and two H atoms of urea tend to be oriented towards two O atoms of Sn (OH) 3-, so that adsorption of Sn (OH) 3-on the carbon substrate in the electrolyte is enhanced; the problems of tin death, hydrogen evolution and the like of a current tin-air battery charge-discharge anode are solved, the service life of the battery is prolonged, the reliability of the battery is improved, low-cost and high-performance development of the tin-air battery can be promoted, and the commercialized application process of the tin-air battery is greatly promoted.

The invention discloses a method for preparing a chiral benzhydrol compound through asymmetric hydrogenation of o-amido benzophenone under catalysis of rhodium. The chiral rhodium catalyst is generated in situ from a metal rhodium salt and a chiral phosphine-phosphoramidite ligand in various solvents. Compared with other methods for synthesizing chiral benzhydrol, the method has the characteristics of cheap catalyst, easiness in preparation of chiral ligand, mild reaction conditions, simplicity and convenience in operation, high yield, high enantioselectivity and the like, and can be applied to large-scale preparation of chiral benzhydrol compounds. The method is also suitable for efficient preparation of the rice plant growth regulation inhibitor (S)-Inabenide, the yield can reach 92%, the enantioselectivity can reach 96%, and the method has good industrial application prospects.

The present invention discloses a process for preparing compound of Lifitegrast of Formula (I) or a salt thereof. Briefly, The present invention discloses a process for the preparation of Lifitegrast of Formula I from alkyl (S)-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6- carboxamido)-3-(3 (methylsulfonyl)phenyl)propanoate a compound of Formula V via 5 transesterification of Phenyl (S)-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6- carboxamido)-3-(3)(methylsulfonyl)phenyl) propanoate of Formula IV.

The invention discloses an adsorbent resin and a preparation method thereof, and belongs to the technical field of wastewater adsorption treatment. The preparation method comprises the following process steps: S1, taking p-chloromethyl styrene, styrene and n, n '-(4, 4'-methylene diphenyl) bismaleimide as monomers, mixing the monomers, a cross-linking agent and a pore-foaming agent to obtain an oil phase, and carrying out suspension polymerization in the presence of a dispersion phase, an additive and an initiator to obtain a polymerization product; s2, carrying out Soxhlet extraction and other treatments on the polymerization product to obtain chloromethylated amide group modified polystyrene; s3, carrying out amination treatment on the chloromethylated amido group modified polystyrene to obtain an amination product; and S4, washing and vacuum drying the amination product obtained in the step S3 to obtain the adsorption resin. The adsorbent resin obtained by the method can effectively enrich long-chain alkyl carboxylic acid in a water body, and has the advantages of low cost, high adsorption capacity, strong selectivity and excellent cyclic regeneration stability.

This invention relates to a thickening and water-retaining agent with a branched network structure and its preparation method. The raw materials, by weight, include: 10 parts of unsaturated acid monomer; 5-40 parts of acrylamide; 1-5 parts of unsaturated amide monomer; 3-10 parts of unsaturated sulfonate monomer; 2-5 parts of workability-modifying monomer; 0.5-2 parts of oxidant; 0.5-6 parts of polymerizable reducing agent; and water. The thickening and water-retaining agent with a branched network structure prepared by this invention, during the hydration process of cement, continuously adds branched structure through the hydrolysis effect of amide groups, and continuously and slowly releases free water to replenish the free water consumed during hydration. This meets the flowability requirements of concrete after hydration, solving the problems of existing thickening and water-retaining agents that cannot simultaneously meet the initial and post-hydration thickening and water-retaining properties and flowability requirements of concrete, and also addressing the issue of storage stability.

The present application provides an organosilicon thermally conductive phase-change material and a preparation method thereof. The organosilicon thermally conductive phase-change material comprises, by mass, 100 parts of ethylene cyclocarbonate-modified organopolysiloxane, 64-115 parts of amino-modified organopolysiloxane, 5.5-12 parts of cyclic acid anhydride, 2-5 parts of antioxidant, 1.5-3 parts of silane coupling agent, and 300-800 parts of thermally conductive powder. The present application does not contain a phase-change material, fundamentally solving the problem of easy leakage of phase-change materials. The cross-linked network is formed by the reaction of ethylene cyclocarbonate-modified organopolysiloxane and amino-modified organopolysiloxane. The cyclic carbonate group reacts with the amino group to produce carbamate groups and hydroxyl groups, and the cyclic acid anhydride reacts with the amino group to produce amide groups and carboxyl groups. As a result, the cross-linked network contains a large number of polar groups. At room temperature, these polar groups further form a cross-linked network. When heated, the cross-linked network weakens, and the phase-change material becomes viscous, achieving the phase-change function.

The invention relates to a drug-loading material containing modified sodium alginate and application of the drug-loading material in pesticide preparations, and belongs to the technical field of pesticide pharmacy, the drug-loading material containing modified sodium alginate contains an N-vinyl caprolactam chain segment, the volume phase transition temperature of the drug-loading material can be regulated and controlled through the concentration of metal ions, and the temperature-sensitive chain segment collapses at high temperature, so that the drug-loading material containing modified sodium alginate has good stability. At low temperature, the network is loose to promote release, at low temperature, the network is compact, ineffective release is inhibited, temperature fluctuation in the field is adapted, metal ions, carboxyl of modified sodium alginate, carboxyl of dehydroabietic acid and acylamino of N-vinylcaprolactam form a dynamic coordination network, accurate gradient release is presented in weak-acid, neutral and alkaline environments, and the metal ion-modified hydrogel has good biocompatibility. Amino and carboxyl of the chitosan quaternary ammonium salt form an acid-base buffer pair, the pH response interval is further refined, release disorder caused by small fluctuation of soil acidity and alkalinity is avoided, the drug-loading material has a temperature and pH dual response function, and targeted release in a pest and disease damage high-incidence environment (high temperature and specific pH) is achieved.

The invention provides a preparation method of a novel chiral thiourea / phosphine bifunctional organic catalyst with a cis-cyclic 1, 2-phosphinamine skeleton and application of the novel chiral thiourea / phosphine bifunctional organic catalyst in an asymmetric catalytic reaction. The chiral organic catalyst is prepared by taking cis chiral 2-(diphenylphosphine)-1, 2, 3, 4-tetrahydro-1-naphthylamine and an isothiocyanate compound as raw materials through a one-step reaction under a mild condition. The chiral thiourea / phosphine bifunctional organic catalyst is simple to prepare and stable in property, and shows excellent catalytic activity and stereoselectivity in an asymmetric hydrosilylation reaction of o-amido benzophenone.

The application belongs to the technical field of compound preparation, and discloses a kind of 3-amido quinoline structure containing compound, its chemical structural formula is as follows: wherein, R1 is halogen;R2 is N-substituted five or six-membered nitrogen heterocyclic primary amine group or 3-substituted six-membered nitrogen heterocyclic primary amine group;R3 is 4-methylphenyl or 4-benzyl morpholinyl.The 4-methylphenyl or 4-benzyl morpholinyl substituted terminal alkyne ketone, 2-amino-5-halogen benzaldehyde is used as raw material to synthesize intermediate product, and the intermediate product is reacted with N-substituted five or six-membered nitrogen heterocyclic primary amine or 3-substituted six-membered nitrogen heterocyclic primary amine, to obtain a variety of 3-amido quinoline structure containing compounds, the raw material is widely sourced, low in price, green and environmentally friendly, and easy to operate, simple in condition, fast in reaction time, convenient in post-treatment, high in product yield, suitable for large-scale preparation, and has wide application prospect.

The present invention relates to a process for stereoselective polyene cyclization to produce tricyclic compounds of formula (I), wherein X is CH2or C=O, comprising reacting a compound of formula (II), wherein X is CH2or C=O and wherein the curved line indicates the E- or Z-configuration, in the presence of a catalytic amount of a Bronsted acid having an acidic sulfonamide moiety.(I)(II)

The application belongs to the technical field of medicine synthesis, and particularly relates to a preparation method of furosemide. The preparation method of furosemide comprises the following steps: chlorosulfonation: reacting chlorosulfonic acid and 2,4-dichlorobenzoic acid, hydrolyzing, filtering, and obtaining 2,4-dichloro-5-sulfonyl chlorobenzoic acid; amination: adding 2,4-dichloro-5-sulfonyl chlorobenzoic acid into ammonia water, reacting, neutralizing, filtering, purifying, and obtaining 2,4-dichloro-5-sulfonamidobenzoic acid; condensation: reacting 2-furfurylamine and 2,4-dichloro-5-sulfonamidobenzoic acid, and obtaining furosemide crude product; decolorization: adding the furosemide crude product into a saturated sodium bicarbonate solution, adding activated carbon for decolorization, neutralizing, and crystallizing, and thus furosemide product is obtained. The raw material used in the application is easy to obtain and low in price, the comprehensive reaction period is short, the amount of hazardous waste generated is small, the prepared furosemide is high in purity and high in total yield, the comprehensive cost of the whole preparation process is low, and the application is suitable for industrial production.

The invention discloses amido polylactic acid as well as a preparation method, application and an application method thereof. The amido polylactic acid is prepared from polylactic acid, an oxidizing agent, a dicarboxyl amine compound, a hydroxyl-containing acyl chloride monomer and a catalyst. The preparation method comprises the following steps: firstly, respectively preparing a dihydroxy amide monomer and polylactic acid with carboxyl at two ends, then esterifying the dihydroxy amide monomer and the polylactic acid to obtain an amido polylactic acid fiber with an amido group, and blending the amido polylactic acid fiber with a polyethylene fiber to prepare the amido polylactic acid degradation film material. According to the invention, amide groups are introduced into polylactic acid molecules through a chemical method, so that the polylactic acid is endowed with new performance, the heat resistance, chemical stability, biocompatibility and the like of the polylactic acid can be improved, and the formed amido polylactic acid degradable film material has the characteristics of degradability and antibacterial property, is relatively high in heat resistance and mechanical property, and can be widely applied to the field of degradable film materials. The method can be widely applied to the biomedical field.