105 results about "Aldol condensation" patented technology

The invention relates to a preparation method of a high-lithium-affinity vinylene covalent organic framework material serving as a lithium metal negative electrode interface protective layer. The method comprises the following steps: firstly, by utilizing a simple hydrothermal synthesis method, taking 1, 3, 5-trimethyl-2, 4, 6-triazine (TMT) and 2, 2-bipyridine-5, 5-diformaldehyde (BPY) as monomers, and carrying out Aldol condensation reaction to synthesize a covalent organic framework material connected by a vinylene bond, which is named as viCOF-bpy; the electrochemical performance of the material is verified by modifying the surface of a copper pole piece with the viCOF-bpy material and then assembling a battery. The lithium-loving group on the material skeleton can promote the migration of lithium ions, and the vinylidene has very strong chemical stability, so that the electrochemical performance of the lithium metal battery can be effectively improved.

The invention belongs to the field of organic synthesis, and discloses an aldol condensation reaction method and a catalyst thereof.The method comprises the steps that in the presence of a composite catalyst, a substrate 1 and a substrate 2 are subjected to an aldol condensation reaction, after the reaction is finished, an aldol condensation product is collected from reaction products, according to the method, aldol condensation reaction of fatty aldehyde or aromatic aldehyde is catalyzed by adopting the novel composite catalyst, and the method has the advantages of being mild in reaction condition, environmentally friendly, efficient and simple in post-treatment.

The invention provides a preparation method of an omariglitazone intermediate, which comprises the following steps: by taking p-halogenated benzaldehyde as a raw material, carrying out aldol condensation reaction, hydrolysis, decarboxylation, reduction, ring closing and the like to obtain an intermediate as shown in a formula 9, carrying out catalytic reaction, reduction reaction, ring closing and the like to obtain an intermediate as shown in a formula 13, and finally hydrolyzing to obtain a target product omariglitazone intermediate A. According to the invention, links of precious metal use and chiral resolution (key steps influencing cost and yield) in the prior art are avoided, and a method for synthesizing a single configuration through a chemical method is adopted, so that the yield is greatly improved, and the production cost is greatly reduced; meanwhile, a synthesis route is broken through, a target product is synthesized through cheap initial materials, and post-treatment is simpler and more controllable.

The present application relates to the technical field of alcohol aldehyde condensation reaction, and discloses an alcohol aldehyde condensation reaction method.The alcohol aldehyde condensation reaction method is carried out in an alcohol aldehyde condensation reaction device, the alcohol aldehyde condensation reaction device comprises a micro-channel alcohol aldehyde condensation reactor and an alcohol aldehyde condensation tube reactor which are connected in series; in the presence of an alkali catalyst, a reaction raw material n-butyl aldehyde is subjected to a first alcohol aldehyde condensation reaction in the micro-channel alcohol aldehyde condensation reactor to obtain a first alcohol aldehyde condensation reaction product; and the first alcohol aldehyde condensation reaction product is subjected to a second alcohol aldehyde condensation reaction in the alcohol aldehyde condensation tube reactor.The method uses a micro-channel alcohol aldehyde condensation reactor and an alcohol aldehyde condensation tube reactor to replace a full-mixing kettle reactor in the prior art to carry out alcohol aldehyde condensation reaction, so that the yield of a by-product heavy carbon alcohol can be significantly reduced, and the yield of a target product can be improved.

The present invention relates to the technical field of organic synthesis. Provided is a method for preparing 2,6-bis(4-azidobenzylidene)-4-methylcyclohexanone, comprising the following steps: S1, subjecting 4-nitrobenzaldehyde and trimethylsilyl azide to a nucleophilic aromatic substitution reaction to obtain 4-azidobenzaldehyde; S2, subjecting 4-azidobenzaldehyde and 4-methylcyclohexanone to an aldol condensation reaction, so as to obtain 2,6-bis(4-azidobenzylidene)-4-methylcyclohexanone. The described technical solution addresses the problems in the related art where the process for synthesizing 2,6-bis(4-azidobenzylidene)-4-methylcyclohexanone has low product yield, high costs and high energy consumption, and is not conducive to large-scale industrial production.

The invention discloses a preparation method of a composite nanofiltration membrane, which is characterized in that the surface of an ultrafiltration membrane is coated with natural low-cost biological materials carrageenan and sodium carboxymethyl cellulose, so that the environmental friendliness and technical feasibility in the field of water treatment are enhanced; the preparation method comprises the following steps: firstly preparing a composite membrane, then carrying out cross-linking modification on the surface of the membrane through aldol condensation reaction, and constructing a compact and stable three-dimensional network structure selection layer after cross-linking, so that the composite membrane keeps structural stability under extreme pH conditions and in an oxychlorination environment, meanwhile, the composite membrane is endowed with efficient nanofiltration performance, and the composite membrane can be practically applied to industrial chromium-containing wastewater.

The present application relates to the technical field of chemical essence and flavor, and particularly relates to a decenoic acid ester compound, a preparation method and application thereof, and comprises the following steps: (1) preparing 2-(4-methyl-benzylidene) heptanal: under the condition of an inorganic alkaline reagent, p-methylbenzaldehyde and n-heptanal are subjected to aldol condensation reaction to synthesize 2-(4-methyl-benzylidene) heptanal; (2) preparing 2-(4-methyl-benzylidene) heptyl alcohol: under the condition of a reducing agent, 2-(4-methyl-benzylidene) heptanal is reduced to 2-(4-methyl-benzylidene) heptyl alcohol; (3) preparing 5-decenoic acid 2-(4-methyl-benzylidene) heptyl alcohol ester: under the catalysis of an acid, 5-decenoic acid and 2-(4-methyl-benzylidene) heptyl alcohol are subjected to esterification to synthesize 5-decenoic acid 2-(4-methyl-benzylidene) heptyl alcohol ester. The compound in the present application has jasmine aroma and milk aroma, has elegant aroma, has long-lasting aroma, and has important use in the field of daily chemical flavoring.

The invention provides a difunctional acid-base synergistic catalyst, a preparation method and application in aldol condensation reaction, the catalyst is a modified halloysite nanotube-loaded barium-based catalyst, the modified halloysite nanotube-loaded barium-based catalyst is adopted for acid-base synergistic catalysis, the catalytic activity of the catalyst is greatly improved, and the catalytic activity of the catalyst is improved. The aldol condensation reaction is rapidly carried out, and the reaction yield is up to 98.0%. The method is mild in reaction condition, simple in production process, clean and environment-friendly in process and high in continuity degree, and the catalyst is easy to prepare and high in stability.

The application discloses a catalyst for preparing high-level unsaturated aldehyde through hydroxy aldehyde condensation reaction and a preparation method thereof. Specifically relates to a method for preparing propylene aldehyde through hydroxy aldehyde condensation reaction of a mixed solution of formaldehyde and acetaldehyde, in which, a basic metal is loaded on a modified CeO2 carrier; the reaction is carried out in a fixed bed under normal pressure; the catalyst provided by the application is cheap, and the preparation method is simple, efficient, and has the characteristics of high conversion rate of acetaldehyde in the reaction process, the highest conversion rate can reach 95%, and the selectivity of propylene aldehyde can reach 70%.

The invention belongs to the field of catalysis, and provides an Nb-based composite oxide supported metal catalyst, a preparation method and an application of the Nb-based composite oxide supported metal catalyst in preparation of aviation oil through hydrodeoxygenation. The catalyst comprises a dual carrier of gamma-Al2O3 and Nb2O5 (or NbOPO4), and one or more hydrogenation active metals. The hydrodeoxygenation catalyst provided by the invention has good acidity and hydrogenation performance under the interaction of the two carriers, and the acidity and hydrogenation performance are proved to be superior to those of an original single-carrier catalyst through characterization; the performance of the catalyst in hydrodeoxygenation of a biomass derivative aldol condensation product (a long-chain oxygen-containing compound) to prepare aviation oil is far superior to that of a single-carrier catalyst with the same metal loading capacity.

The application discloses a tetrahydroindazole biphenyl type fluorescent probe for detecting hydrazine and a preparation method and application thereof. The fluorescent probe is (3-(4-((2,5,8,11-tetraoxatridecan-13-yloxy)-4'- (6,6-dimethyl-2-(4-nitrophenyl)-4,5,6,7-tetrahydro-2H-5,7-methanobenzimidazole-3-yl)-1,1'-biphenyl-3-yl)-2-(pyridin-4-yl)acrylonitrile (TOPIB-PAN for short). The application uses 4-((2,5,8,11-tetraoxatridecan-13-yloxy)-4'- (6,6-dimethyl-2-(4-nitrophenyl)-4,5,6,7-tetrahydro-2H-5,7-methanobenzimidazole-3-yl)-1,1'-biphenyl-3-formaldehyde (TOPIB-CA for short) as a raw material, and performs an aldol condensation reaction with 4-pyridine acetonitrile to obtain the compound TOPIB-PAN. The compound TOPIB-PAN can specifically react with hydrazine. Under the irradiation of ultraviolet light with a wavelength of 365nm, the solution containing the compound emits green fluorescence. After hydrazine is added into the solution, the fluorescence color of the solution changes from green to colorless. Therefore, the compound can be used as a fluorescent probe for detecting hydrazine, has many advantages such as a low detection limit (7.9*10 ‑ 8 mol / L), a wide pH use range (3-11) and high light stability (>1800min), and has a good application prospect.

The invention belongs to the technical field of catalyst synthesis, and particularly discloses a preparation method of a first-generation Grubbs catalyst, dichlorophenyl ruthenium (II) dimer is used as a metal source raw material, benzaldehyde and tricyclohexylphosphine are combined to synthesize the first-generation Grubbs catalyst, in the reaction process, a dendritic multi-site di (pentafluorophenyl) boric acid catalyst is introduced, and the first-generation Grubbs catalyst is synthesized by using dichlorophenyl ruthenium (II) dimer as a metal source raw material. A di (pentafluorophenyl) boron group at the tail end forms a superacid center due to a strong electron absorption effect, and benzaldehyde carbonyl can be efficiently activated; the dendritic skeleton provides a multi-site synergistic effect and steric configuration control, enhances the substrate enrichment and transition state stabilization capability, and significantly reduces the activation energy generated by the Ru = CHPh key intermediate, and meanwhile, the key steps of further accelerating aldol condensation, metal-carbon double bond generation and the like are combined with a proper amount of alkaline accelerator, so that the preparation method has the advantages of high yield and high yield. The efficient introduction of a benzaldehyde key C1 construction unit is realized, the reaction condition is mild, and the operation is simple and convenient.

The present invention relates to a method for producing a compound represented by the following formula (I), which comprises a step of subjecting a compound represented by the following formula (II) and a compound represented by the following formula (III) to an aldol condensation reaction in the presence of [1] a compound represented by the following formula (I) and [2] a compound represented by the following formula (IV): TIFF0007773005000076.tif1968 The present invention relates to [3] a method for producing a compound represented by the following formula (VI), which comprises a step of subjecting a compound represented by the following formula (V) to a reduction reaction together with an ammonia equivalent. TIFF0007773005000077.tif2144

The invention relates to the technical field of medicines, and provides a synthesis method of a key intermediate of fluralana, which comprises the following steps: S1, carrying out aldol condensation reaction on a compound I and a compound II to obtain a compound III; s2, carrying out ring closing reaction on the compound III and hydroxylamine to obtain a compound IV; s3, the compound IV is subjected to an alkylation reaction under the action of a catalyst aluminum trichloride, and a compound V is obtained; s4, the compound V reacts with a Grignard reagent and then reacts with carbon dioxide, and a compound VI is obtained. Through the technical scheme, the problems of high cost, high impurity content and complex process of the existing synthesis method in the related technology are solved, a good foundation is laid for preparing flurala, and the process is simple to operate, high in conversion rate in each step and suitable for workshop production.

The invention discloses a tri-acceptor polymer based on diisoindigo and a preparation method and application thereof, and belongs to the technical field of organic semiconductor materials. The invention relates to a tri-acceptor polymer based on diisoindigo. In the structure of the tri-acceptor polymer, R1 and R2 are selected from at least one of C5-C80 straight-chain or branched-chain alkyl groups; x, Y and Z in the structure are selected from fluorine or hydrogen; and the polymerization degree n of the tri-acceptor polymer is 5-200. The tri-acceptor polymer is prepared through a Stille coupling reaction, an aldol condensation reaction and a Stille copolymerization reaction in sequence, the synthesis route is simple and easy to implement, the number of synthesis steps is small, and the method is suitable for large-scale synthesis. A field effect transistor taking the tri-acceptor polymer as an organic semiconductor layer has high bipolar transmission property, the highest electron mobility can reach 4.08 cm < 2 > V <-1 > s <-1 >, the highest hole mobility can reach 5.51 cm < 2 > V <-1 > s <-1 >, and the tri-acceptor polymer has a good application prospect in organic field effect devices.

The invention relates to an anhydrous formaldehyde alcohol solution as well as a preparation method and application thereof, the preparation method comprises the following steps: (1) under the action of an inorganic base catalyst, carrying out first mixing on paraformaldehyde and an alcohol solution for depolymerization reaction to obtain a formaldehyde alcohol solution containing inorganic base; and (2) carrying out separation treatment on the formaldehyde alcohol solution containing the inorganic base to obtain the anhydrous formaldehyde alcohol solution. According to the preparation method, the catalyst-containing polyoxymethylene alcohol solution is firstly obtained, then the catalyst in the polyoxymethylene alcohol solution is separated out, and the anhydrous formaldehyde alcohol solution is obtained, so that the anhydrous formaldehyde alcohol solution can stably exist and can be used in aldol condensation reaction, and the preparation method provided by the invention is simple in process, easily available in raw materials and low in cost. The method is suitable for large-scale industrial application.

The invention discloses a method for preparing isobutyraldehyde by catalyzing methanol and ethanol through a composite metal oxide catalyst, and particularly relates to a method for preparing isobutyraldehyde by catalyzing methanol and ethanol through an aldol condensation reaction by taking V2O5 as a main metal oxide catalyst. The introduced metal oxides comprise one or more of TiO2, Al2O3, ZrO2, SiO2, La2O3 and Nb2O5, and the composite metal oxide catalyst mainly containing V2O5 is prepared by one or more methods of mechanical grinding and is used for preparing isobutyraldehyde from methanol / ethanol. The method has the advantages that the metal oxide is introduced to optimize the oxygen supply activity and restore the oxidation capacity of the vanadium catalyst, so that the product selectivity is improved.

The application discloses a preparation method of alpha-tuliketone, relates to organic synthesis technology utilization, and the preparation is that 4,8-dimethyl-3,7-nonadiene-2-ketone and triacetal are subjected to aldol condensation reaction under the action of acid-base bifunctional catalyst to generate alpha-tuliketone; the acid-base bifunctional catalyst is obtained by grafting organic base onto carboxylic acid functionalized mesoporous material.The acid-base bifunctional catalyst is simple in preparation, good in stability and reusable, is used for catalyzing the reaction of 4,8-dimethyl-3,7-nonadiene-2-ketone and triacetal, can directly generate target product alpha-tuliketone by one-pot method, is high in reaction activity, short in reaction period, simple in post-treatment, simplifies process, is high in yield, and the yield can reach more than 95%.

The application discloses a synthesis method of (2E,4Z)-2,4-decadienoic acid ethyl ester, and belongs to the technical field of perfume synthesis. The method comprises the following steps: 3-octyn-1-ol is subjected to the oxidation of Akira Yoshide to obtain 2-octynal; after the aldol condensation and decarboxylation reaction of 2-octynal and malonic acid, E-dec-2-en-4-ynoic acid is obtained; the esterification reaction of the obtained carboxylic acid is carried out to obtain E-dec-2-en-4-ynoic acid ethyl ester; and the enynoic acid ester is subjected to cis-reduction to obtain (2E,4Z)-2,4-decadienoic acid ethyl ester. The synthesis method has the advantages of simpler operation, less waste, high selectivity, guaranteed yield and product quality, and is more suitable for industrialized scale production.

The application belongs to the technical field of pharmaceutical chemistry, and specifically discloses a chalcone derivative and a preparation method thereof. 2,4-dihydroxy formaldehyde is used as an initial raw material, isopentenyl is introduced into 2,4-dihydroxybenzaldehyde through a Friedel-Crafts reaction, and then a heterocycle is introduced through a hydroxy aldehyde condensation reaction of the heterocycle-substituted formaldehyde, so that a chalcone structure is formed. The prepared chalcone derivative has a structural formula as shown in Formula I, and the physicochemical properties thereof are studied. It is proved that the chalcone derivatives I-4, I-5, I-7, I-8, I-9, I-10, I-11, I-12 and I-14 all show a strong inhibitory effect on the proliferation of four tumor cells (PC9, MDA-MB-231, SMMC-7721 and SGC-7901). Among them, the chalcone derivative I-4 can effectively inhibit the proliferation of human lung cancer PC9 and H1975 cells in a concentration-dependent manner, and shows good in-vivo anti-tumor activity and can induce iron death of human lung cancer PC9 and H1975 cells, and has a good application prospect as an anticancer drug.

The invention relates to the technical field of new energy, in particular to a preparation method of C9-C13 cycloalkane. The method comprises the following steps: in the presence of a base catalyst and a solvent, carrying out aldol condensation reaction on acetophenone and furfural or phenylacetaldehyde and furfural to obtain (E)-3-(cyclopent-1, 3-diene-1-yl)-1-phenylpropyl-2-ene-1-one or (Z)-3-(furan-2-yl)-2-phenylacrolein; under the action of a nickel-loaded catalyst, (E)-3-(cyclopentyl-1, 2, 4-triazole-3-yl)- The C9-C13 cycloalkane prepared by adopting the preparation method disclosed by the invention has the advantages of high density, high volume calorific value, excellent low-temperature fluidity and good thermal stability, and can be used for preparing the C9-C13 cycloalkane. The problems of low fuel energy density and insufficient performance in the prior art are solved.

The invention relates to the technical field of chemical synthesis, in particular to a synthesis method of matrichthrin, which comprises the following steps: S1, under an alkaline condition, carrying out aldol condensation reaction on propionaldehyde to obtain a first reaction mixture containing 2-methyl-2-pentenal; s2, in the presence of a hydrogenation catalyst, 2-methyl-2-pentenal in the first reaction mixture obtained in the step S1 is subjected to a hydrogenation reaction, and a second reaction mixture containing 2-methylvaleraldehyde is obtained; s3, in the presence of an oxidation catalyst, 2-methylvaleraldehyde in the second reaction mixture obtained in the step S2 and oxygen or oxygen-containing gas are subjected to an oxidation reaction, and a third reaction mixture containing 2-methylvaleric acid is obtained; and S4, in the presence of an esterification catalyst and a water-carrying agent, carrying out esterification reaction on the 2-methylvaleric acid in the third reaction mixture obtained in the step S3 and ethanol to obtain matrichthrin. The requirement for supplementing manganese acetate is remarkably reduced, and the production cost is reduced.

The invention discloses a method for macroscopically preparing solid-state fluorescent carbon dots and the solid-state fluorescent carbon dots. The method comprises the following steps: S1, mixing an amide substance and acetaldehyde according to a preset proportion to obtain a precursor solution; s2, weighing a preset amount of strong alkali solid as a catalyst, rapidly adding the strong alkali solid into the precursor solution, and performing ultrasonic mixing to obtain a reaction solution; s3, heating the reaction solution and carrying out reflux reaction; s4, after the reaction is completed, naturally cooling a reaction solution to room temperature, separating and purifying, and taking a solid product; and S5, drying the solid-state product in a drying oven to obtain the target product solid-state fluorescent carbon dot. According to the synthesis method disclosed by the invention, on the basis of a mature aldol condensation reaction mechanism, by accurately regulating and controlling key parameters such as the molar ratio of reactants, the reaction temperature and time and the like, the generation of byproducts is effectively inhibited, the yield is remarkably improved (the yield can be up to 70-80%), and large-scale efficient preparation from gram level to kilogram level is realized. Meanwhile, the adopted raw materials are low in cost and wide in source, the reaction can be carried out under the conditions of normal pressure and lower temperature, the operation safety is high, and the energy consumption is low. And the post-treatment process only relates to conventional centrifugation, washing and drying steps, and no complex purification equipment is needed, so that the production cost and the process complexity are greatly reduced. Therefore, the method has great industrial large-scale production potential.

The application discloses a synthesis method of Triclabendazole, which comprises the following steps: starting from a compound of formula (11) and a compound of formula (10), a Pictet-Spengler reaction is performed, then intermolecular aldol condensation of a compound of formula (8) and a compound of formula (14) is performed, a fragment connection product of formula (15) is obtained through the reaction, then asymmetric ketal oxidation is performed to obtain a compound of formula (19-II), an intramolecular Stecker reaction is performed to obtain a compound of formula (5), then stereoselective decarboxylation protonation of palladium catalysis is performed to obtain a compound of formula (3), then a protecting group is removed, and an ethyl ester is reduced to obtain a compound of formula (26); then, the Triclabendazole shown in formula (A) is synthesized from the compound of formula (26). The method is mild in conditions, simple in operation, and raw materials are easy to obtain, and is suitable for large-scale production.

The invention discloses a preparation method of 2-aza [5] helicene, and belongs to the field of organic synthesis. The preparation method comprises the following steps: firstly, taking commercialized 2, 3-dihydrophenanthrene-4 (1H)-ketone as an initial raw material, and generating a 4-bromo-1, 2-dihydrophenanthrene-3-formaldehyde compound through a Vilsmeier-Haack reaction; secondly, the 4-bromo-1, 2-dihydrophenanthrene-3-formaldehyde and the 2, 3-dichloro-5, 6-dicyanobenzoquinone are subjected to oxidative aromatization, and a 4-bromophenanthrene-3-formaldehyde compound is generated; then, a Suzuki coupling reaction is catalyzed through palladium, and axial chirality 4-(4-methylpyridine-3-yl) phenanthrene-3-formaldehyde is constructed; and finally, carrying out intramolecular Aldol condensation / cyclization reaction to realize'shaft-to-screw 'transfer, so as to successfully obtain the target product 2-aza [5] helicene. The raw materials adopted by the method are cheap and easy to obtain, and the synthesis method is simple to operate and meets the requirements of industrial production.

This invention discloses a method for producing 4-hydroxy-2-pentanone from acetone and acetaldehyde, belonging to the field of fine chemical intermediate synthesis technology. The method uses bio-based acetone and bio-based acetaldehyde as raw materials, and 1,8-diazabicyclo[5.4.0]undec-7-ene as a catalyst. In a DBU-H₂O catalytic system, high-purity 4-hydroxy-2-pentanone is obtained through a cross-aldol condensation reaction followed by separation and purification. This invention solves the technical problems of low product yield, numerous by-products, dark product color, strong odor, and difficulty in catalyst recovery in existing technologies by optimizing reaction parameters and selecting specific catalysts. The reaction conditions are mild, the operation is simple, and the energy consumption is low. The catalyst can be recycled, and all raw materials are bio-based, meeting the requirements of green chemical development. It is suitable for large-scale industrial production, and the product can be widely used in bakelite preparation, flavorings, pharmaceutical intermediates, and other fields.

The invention discloses a preparation method of biomass-based polyalkyl substituted cyclopentane structure lubricating oil, and belongs to the field of organic synthesis. The preparation method comprises the following steps: performing aldol condensation on biomass-derived 2-undecanone and 5-methylfurfural, performing self [2 + 2] cycloaddition reaction to prepare a precursor of the lubricating oil with the polyalkyl substituted cyclopentane structure, and further performing hydrodeoxygenation to obtain the lubricating oil with the polyalkyl substituted cyclopentane structure. The lubricating oil precursor with the polyalkyl substituted cyclopentane structure has a high-tension four-membered ring structure, hydrodeoxygenation is carried out under co-catalysis of an activated carbon supported metal hydrogenation catalyst, a molecular sieve, heteropoly acid or aluminum oxide, high-performance lubricating oil with the cyclopentane structure is obtained through a reaction and a framework rearrangement process, the kinematic viscosity of the lubricating oil is 14.25 mm < 2 > / s at the temperature of 40 DEG C, and the kinematic viscosity of the lubricating oil is 3.49 mm < 2 > / s at the temperature of 100 DEG C.

The invention discloses a total acceptor type conjugated polymer and a preparation method and application thereof, the total acceptor type conjugated polymer is an acceptor-acceptor type conjugated polymer based on a sulfur-containing heterocycle isoindigo derivative and benzodifuran diketone, the structural general formula of the total acceptor type conjugated polymer is shown in the specification, in the formula, X is C or N, R1 is a C8-C24 alkane chain, and n is greater than or equal to 1. The total acceptor conjugated polymer is synthesized through aldol condensation polymerization and has good solution processability, the molecular structure has high planarity, the LUMO energy level and the HOMO energy level are reduced due to the electron deficiency capability, and the electron transmission performance of a material can be promoted. The polymer can be used as an electron transport material and is applied to the field of organic field effect transistors.

The invention discloses high-strength polyelectrolyte photo-thermal hydrogel as well as a preparation method and application thereof. The preparation method of the high-strength polyelectrolyte photo-thermal hydrogel comprises the following steps: dispersing polyvinyl alcohol, a polymerizable ionic liquid monomer, a vinyl cross-linking agent, an aldehyde cross-linking agent, a photo-thermal material and an acid catalyst into water to obtain a pre-gel solution; and sequentially carrying out aldol condensation reaction and radiation cross-linking reaction on the pre-gel solution to obtain the high-strength polyelectrolyte photo-thermal hydrogel with the interpenetrating double-network structure. The photo-thermal hydrogel has the advantages of high mechanical strength, excellent photo-thermal evaporation performance, active salt management and recovery capability and waste heat power generation function. The inherent contradiction among the mechanical strength of the photo-thermal hydrogel, the stability of a high-salt environment and the energy efficiency is successfully solved through sequential crosslinking. The method is simple in process and easy to expand, and has huge application potential in the fields of seawater desalination, salt lake resource development, distributed water and electricity combined supply in an off-network area and the like.

The invention belongs to the technical field of medicinal chemistry, and discloses a 2, 5-diketopiperazine compound, a synthesis method, a composition and application. The synthesis method comprises the following steps: synthesizing or providing 2, 3, 4, 5 or 6-substituted benzaldehyde A; synthesizing or providing an intermediate 2, 5-diketopiperazine derivative B; 2, 3, 4, 5 or 6-substituted benzaldehyde A and an intermediate 2, 5-diketopiperazine derivative B are subjected to Aldol condensation to obtain the compound with the structure as shown in the formula (I). The compound is novel in structure, part of the compound has excellent anti-tumor activity and optical stability, and the compound has good development prospects.