121 results about "1,3-Butanediol" patented technology

A non-naturally occurring microbial organism having a 1,3-butanediol (1,3-BDO) pathway includes at least one exogenous nucleic acid encoding a 1,3-BDO pathway enzyme or protein expressed in a sufficient amount to produce 1,3-BDO. A method for producing 1,3-BDO that includes culturing the this non-naturally occurring microbial organism under conditions and for a sufficient period of time to produce 1,3-BDO.

An ink for ink jet recording and an ink jet recording method which realize an image quality of laser printer on a plain paper in a one-pass printing mode under conditions of a volume of an ink droplet ejected being 5 to 43 Pico liter, a velocity of an ink droplet being 6 to 20 m / sec, frequency of 1 kHz and resolution of 300 dpi or more. The ink for ink jet recording is a penetrating type ink which comprises (1) at least one humectant selected from glycerin, 1,3-butandiol, triethyleneglycol, 1,6-hexanediol, propyleneglycol, 1,5-pentanediol, diethyleneglycol, dipropyleneglycol, trimethylolpropane and trimethylolethane, (2) colorant contained in the amount of 6 % by weight or more, (3) a polyol having 8 to 11 carbon atoms and glycolether, and an anionic surfactants or non-ionic surfactants, the ink has viscosity of 5 mPa.s or more at 25° C. and a surface tension of 40 mN / m or less.

A non-naturally occurring microbial organism having a 1,3-butanediol (1,3-BDO) pathway includes at least one exogenous nucleic acid encoding a 1,3-BDO pathway enzyme or protein expressed in a sufficient amount to produce 1,3-BDO. A method for producing 1,3-BDO that includes culturing the this non-naturally occurring microbial organism under conditions and for a sufficient period of time to produce 1,3-BDO.

A pipette tip formed by a polypropylene substrate coated with a water repellent agent. The water repellent agent contains a silicone resin containing at least one specific substance selected from the group consisting of diisononyl phthalate, diisodecyl phthalate, trioctyl trimellitate and poly (1,3-butanediol adipate). The total mass of the specific substance is 1-30 mass % of the silicone resin.

Embodiments of the invention relate to the enzymatic conversion of bioderived feedstocks to commercially valuable chemicals. The enzymatic conversions of the embodiments of the invention offer the potential for lower cost routes to these value-added chemicals. Some of the chemicals that are useful include nylon intermediates such as caprolactam, adipic acid, 1,6-hexamethylene diamine; butanediols such as 1,4-butanediol, 1,3-butanediol, and 2,3-butanediol; butanols such as 1-butanol, and 2-butanol; succinic acid, butadiene, isoprene, and 3-hydroxypropanoic acid.

The invention relates to a method for synthesizing cosmetic-grade 1,3-butanediol. The method includes the steps that acetaldehyde and water are mixed evenly and then injected into a reaction kettle, and dilute acetic acid is dripped under the alkaline condition so that the reaction system can be neutralized to be neutral; flashing is carried out, acetaldehyde obtained in distillation is recycled, and distillation residual liquid is 3-hydroxybutanal; obtained 3-hydroxybutanal and a catalyst are mixed evenly, hydrogen pressure is kept, centrifugal separation is carried out on the obtained product to obtain the catalyst for recycling, flashing is carried out on the liquor at 120 DEG C to obtain water and the byproducts ethyl alcohol and crotonaldehyde, and reduced pressure distillation is carried out to obtain coarse 1,3-butanediol; purification is carried out. The process of synthesizing 1,3-butanediol through condensation and hydrogenation reduction of an acetaldehyde liquid phase is improved through the steps, and thus the product 1,3-butanediol meets the quality requirement of the cosmetic industry.

PCT No. PCT / JP96 / 02739 Sec. 371 Date May 14, 1998 Sec. 102(e) Date May 14, 1998 PCT Filed Sep. 24, 1996 PCT Pub. No. WO98 / 13436 PCT Pub. Date Apr. 2, 1998A moisturizing composition comprising a trihydric or more water soluble polyhydric alcohol, lecithin and 3-methyl-1,3-butylene glycol, wherein lecithin:the trihydric or more water soluble polyhydric alcohol+3-methyl-1,3-butylene glycol=1:1,000 to 1:1 (weight ratio) and the trihydric or more water soluble polyhydric alcohol:3-methyl-1,3-butylene glycol=1:10 to 20:1 (weight ratio), various bases containing the moisturizing composition, and a cosmetic or external preparation containing the moisturizing composition. The moisturizing composition, bases, and cosmetic and external preparation are excellent in moisturizing properties, and have good stability.

The invention provides a preparation method of 1, 3-butylene glycol. The preparation method comprises following steps: A, acetaldehyde is introduced into a fixed bed reactor, under the effect of a supported type solid basic catalyst, aldol condensation reaction is carried out so as to obtain 3-hydroxybutyraldehyde; and B, 3-hydroxybutyraldehyde is subjected to continuous hydrogenation reaction inthe fixed bed reactor so as to obtain 1, 3-butylene glycol. According to the preparation method, the fixed bed reactor is adopted, at the same time, the supported type solid basic catalyst is adoptedto replace a conventional liquid alkali (such as sodium hydroxide) catalysts, and in the step of hydrogenation reduction, a supported nickel hydrogenation catalyst is adopted. The preparation method is capable of solving problems in the prior art product quality is poor, product yield is low, technology process is complex, and a large amount of waste water and waste residue is generated; aldol condensation quenching step is avoided; side reactions are reduced; relatively high reaction conversion rate and yield are achieved; no neutralizing or desalting process is needed in reaction process; and great improvement of traditional 1, 3-butylene glycol preparation technology is realized.

The invention relates to a Donkey-hide gelatin essence hydrating mask and a preparation method thereof. The mask is prepared from the following raw materials: Donkey-hide gelatin essence, a cucumber extract, a pomegranate extract, a seaweed extract, a palmetto extracting solution, dipotassium glycyrrhizinate, lubrajel oil, glycerinum, 1,3-butanediol, allantoin, sodium hyaluronate, carbomer and triethanolamine; Donkey-hide gelatin essence contains 4% of free amino acid in mass fraction, 80 to 85% of small peptide in mass fraction, and 14% of peptide fragment in mass fraction, wherein the molecular weight of small peptide ranges from 200 to 1,000Da; the molecular weight of peptide fragment ranges from 1,000 to 3,000Da; the pH (Potential of Hydrogen) of the hydrating mask ranges from 5.0 to 7.5. The Donkey-hide gelatin essence hydrating mask has the effects of hydrating, removing wrinkles, increasing skin elasticity, and enabling exquisite, smooth and glossy skin; the anti-allergic test shows that the Donkey-hide gelatin essence hydrating mask has no side effects, is safe and reliable and can be used for a long time as a mask product for skin care.

The invention provides a facial mask, which contains high active ingredients, can whiten skin and improve skin tone and can sooth allergic state of skin. The facial mask comprises the following components in percentage by weight: 1-5 percent of centella, 1-5 percent of tranexamic acid, 0.2-0.8 percent of vitamin B5, 1-5 percent of vitamin B3, 1-3 percent of vitamin C, 0.2-0.8 percent of allantoin, 4-8 percent of licoflavone, 1-3 percent of glucan, 0.2-0.8 percent of sodium hyaluronate, 10-20 percent of propylene glycol, 5-15 percent of 1,3-butanediol, 0.5-1.5 percent of collagen, 1-5 percent of amino acid, 2-8 percent of witch hazel, 1-5 percent of palmitoyl pentapeptide-3, 2-8 percent of hydroxyethylurea, 0.1-0.3 percent of hydroxyethyl cellulose, 0.2-0.8 percent of azone, and 31.1-40.5 percent of deionized water.

The ketogenic diet (KD) has therapeutic implications in many disease states. It was hypothesized ketone precursor supplementation would elevate blood ketone levels to therapeutic ranges (2-7 mM) without need for dietary restriction. The effects of ketogenic agents were tested on blood glucose, ketones, and lipids with a 28-day dose escalation study in male Sprague-Dawley rats: R,S-1,3-Butandiol (BD), acetoacetate ketone ester (KE), and control (H2O) (n≧8). Days 1-28, rats received a daily 5 g / kg intragastric gavage, based on previous toxicology studies. Once weekly, whole blood samples (10 μl) were acquired for analysis of glucose and βHB at 0, 0.5, 1, 4, 8, and 12 hours after test substance administration, or until βHB returned to baseline. At day 1 and 28, 10 μL of whole blood were collected to measure triglycerides, total cholesterol, and HDL concentration. Significant elevation of blood ketone was observed with a significant inverse relationship with blood glucose for the duration of the experiment. There were no significant changes in the lipid panel for any of the substances. There were significant reductions in body weight when animals were treated with either BD or KE as compared to control.

The invention provides a biological antibacterial composition and application of the biological antibacterial composition in cosmetics. The biological antibacterial composition comprises the following components in parts by weight: 0.25 to 1.0 part of epsilon-polylysine, 0.1 to 0.6 parts of nisin, 0.05 to 0.4 parts of natamycin, 3 to 8 parts of glycerin, 2 to 8 parts of 1,3-butanediol and 0.2 to 2 parts of caprylyl glycol. The composition provided by the invention has good antibacterial effect, particularly has a significant synergistic effect on inhibiting candida albicans, pseudomonas aeruginosa and aspergillus niger, can be used in skin care and washing cosmetics, and the additive amount of the original preservatives is reduced.

The invention discloses an electronic cigarette liquid containing tea extracts. The electronic cigarette liquid comprises, by weight, 10.0%-20.0% of polyethylene glycol, 5.0%-10.0% of glycerol, 2.0%-10.0% of deionized water, 1.0%-5.0% of Yunnan Hongda tobacco leaf water extracts, 1.0%-5.0% of Zimbabwe tobacco leaf water extracts, 0%-5.0% of nicotine, 5.0%-15.0% of tea extracts, 2.0%-5.0% of tobacco flavors and the balanced 1,3-butanediol. The invention further discloses a method for preparing the electronic cigarette liquid containing the tea extracts. According to the electronic cigarette liquid and the preparation method, as the tea extracts are added to the electronic cigarette liquid, the cigarette smoking feelings and the harmony can be promoted through tea perfumes, and the harmfulness of smoking can be reduced.

The invention provides a preparation method of 1, 3-butylene glycol. The preparation method comprises following steps: A, acetaldehyde is introduced into a microchannel reactor, under the effect of abasic ionic liquid catalyst, aldol reaction is carried out so as to obtain 3-hydroxybutyraldehyde; and B, 3-hydroxybutyraldehyde is subjected to continuous hydrogenation reaction in a fixed bed reactor so as to obtain 1, 3-butylene glycol. According to the preparation method, the traditional kettle type reaction technology is improved; the microchannel reactor is adopted, at the same time, the basic ionic liquid catalyst is adopted to replace conventional liquid alkali (such as sodium hydroxide) catalysts, and in the step of hydrogenation reduction, a supported nickel hydrogenation catalyst isadopted, and hydrogenation reduction is carried out in the fixed bed reactor. The preparation method is capable of solving problems in the prior art product quality is poor, product yield is low, andtechnology process is complex; relatively high reaction conversion rate and yield are achieved; no neutralizing or desalting process is needed in reaction process; and great improvement of traditional 1, 3-butylene glycol preparation technology is realized. The prepared 1, 3-butylene glycol is colorless and smelless, is high in purity, and is capable of satisfying application requirements of highgrade industries such as cosmetic.

The invention provides a non-naturally occurring microbial organism having n-propanol and isopropanol pathways, 1,4-butanediol (14-BDO) and isopropanol pathways, 1,3-butanediol (13-BDO) and isopropanol pathways or methylacrylic acid (MAA) and isopropanolpathways. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in each of the respective n-propanol, 14-BDO, 13-BDO or MAA and isopropanol pathways. The invention additionally provides a method for co-producing n-propanol and isopropanol, 14-BDO and isopropanol, 13-BDO and isopropanol or MAA and isopropanol. The method can include culturing an n-propanol and an isopropanol co-producing microbial organism, where the microbial organism expresses at least one exogenous nucleic acid encoding an n-propanol, an isopropanol, a 14-BDO, a 13-BDO and / or a MAA pathway enzyme in a sufficient amount to produce each of the respective products, under conditions and for a sufficient period of time to produce each of the respective products.

The present invention demonstrates the therapeutic use of ketone esters for seizure disorders, Alzheimer's disease malignant brain cancer, and other cancers, which are associated with metabolic dysregulation. The administration of a ketogenic diet, such as ketone esters, while concurrently subjecting the patient to a hyperbaric, oxygen-enriched environment resulted in therapeutic ketosis. Optionally, the hyperbaric, oxygen-enriched environment is 100% oxygen at 2.5 ATA absolute. The ketone esters may be derived from acetoacetate and can include R,S-1,3-butanediol acetoacetate monoester, R,S-1,3-butanediol acetoacetate diester, or a combination of the two. The treatment may further include administering at least 10% ketone supplementation, such as acetoacetate, adenosine monophosphate kinase, 1,3-butanediol, or ketone ester, to the patient.

The invention relates to a curable sealant composition broadly comprising a resealable, swellable, reactive sealant and free radical initiator; said resealable, swellable reactive sealant comprises monofunctional monomer(s), multifunctional monomer(s), reactive polymer such as unsaturated styrenic block copolymer, swellable additive, and optional components. The monofunctional monomer is a vinyl ester derivative of versatic acid with C9-C12 carbon atoms, or monoacrylate, monomethacrylate, monoacrylamide, or monomethacrylamide. The multifunctional monomer are di-, tri-, tetra-, and / or penta-functional monomers with vinyl, acrylate, methacrylate, acrylamide, or methacrylamide functionality, such as tricyclodecane dimethanol diacrylate, trimethylolpropane trimethacrylate, 1,3-butylene glycol dimethacrylate or a mixture thereof. The reactive unsaturated polymer is a styrenic block copolymer such as SBS, SIS, S-I / B-S, I-SEBS-I, and mixtures of two or more of these. The swellable additive is selected from saturated block copolymers such as SEBS, SEPS, SEEPS, and I-SEBS-I, or a mixture of these. Free radical initiators are preferably peroxides, although others are acceptable.

The invention discloses a composite membrane with a polymer coating and a preparation method of the composite membrane. According to the preparation method, water-based slurry coats one or two surfaces of a base membrane to form the polymer coating; with deionized water as a solvent, polymer particles, a surfactant and an aqueous adhesive are dispersed into the deionized water to form the water-based slurry; the water-based slurry also contains a suspending agent; the amount of the suspending agent is 3%-25% of total weight of the water-based slurry; and the suspending agent is at least one of potassium chloride, sodium chloride, dichloroacetic acid, ethylene dibromide, 3-bromopyridine, 4,5-dichloro 1,3-dioxolame-2-ketone, dichloroethane, dichloroethylene and 1,3-butanediol sulfite. According to the preparation method, the suspending agent is added to the water-based slurry; the solvent density is improved; and the polymer particles can be evenly dispersed into the deionized water to form the stable water-based slurry, so that the production quality of the composite membrane with the polymer coating is improved; and a basis is laid for preparation of a high-quality lithium-ion battery.

The invention relates to a preparation method of a graphene-like carbon nitride photocatalyst, belonging to the technical field of preparation methods of photocatalytic materials. The method comprises the following steps of: (1) dispersing graphite type carbon nitride in 1, 3-butanediol for performing ultrasonic treatment; (2) performing centrifugal treatment on an obtained suspension to remove a precursor; and (3) evaporating the suspension obtained by centrifugation till dryness so as to obtain a solid, namely the graphene-like carbon nitride photocatalyst. Ultra-thin type graphene-like carbon nitride nano-sheets prepared by utilizing the method disclosed by the invention has good photocatalytic property and photocurrent response, and the graphene-like carbon nitride nano-sheets simultaneously show stronger adsorption capacity. The preparation method provided by the invention has the advantages of low price of raw materials, simple process and mild reaction; and furthermore, the solvent raw materials can be industrially recycled, so that the whole synthesis process is green and environment-friendly, the product cost is effectively reduced, the preparation method is suitable for industrial large-batch production, and the preparation method further has very high application prospects and using values.

A cleaning liquid for an inkjet recording apparatus is provided. The cleaning liquid includes an organic solvent having a boiling point of less than 250° C. and no organic solvent having a boiling point of 250° C. or more. The organic solvent having a boiling point of less than 250° C. includes two or more methoxy-group-containing organic solvents and at least one of 1,2-propanediol, 1,3-propanediol, 1,2-butanediol, and 2,3-butanediol.

The invention discloses a formula of moisturizing milk. The formula comprises following ingredients: glycerin, 1,3-butanediol, cetyl ethyl hexanoate, caprylic / capric triglyceride, one or combination of cetearyl olivate and sorbitan olivate, polydimethyl siloxane, one or more combination of cetyl palmitate, sorbitan olivate and sorbitan palmitate, polyvinyl pyrrolidone, preservative, polyquaternium-10, carbomer, triethanolamine, xanthan gum, hyaluronic acid, EDTA-2Na and the balance being water. The moisturizing milk provided by the invention is good in thickness and sticky feeling; and by using the moisturizing milk, a breathable membrane can be formed on the skin surface, a moisturizing effect is obvious, and the moisture retention is still as before after 8 hours.

A method of reducing odor of 1,3-butylene glycol includes contacting the 1,3-butylene glycol with an activated carbon selected from wood-based activated carbons and chemically activated carbons.

The present invention demonstrates the therapeutic use of ketone esters for seizure disorders, Alzheimer's disease and malignant brain cancer, which are associated with metabolic dysregulation. The administration of ketone esters resulted therapeutic ketosis and neuroprotection against seizures resulting from CNS oxygen toxicity. Supplemental ketones were also found to reduce superoxide production in cultured cortex neurons exposed to hyperbaric oxygen and Aβ-42, and to decrease proliferation and viability in U87 glioma cells. These observations support the therapeutic effect of ketones for seizure disorders, Alzheimer's disease and malignant brain cancer. The ketone esters may be derived from acetoacetate and can include R,S-1,3-butanediol acetoacetate monoester, R,S-1,3-butanediol acetoacetate diester, or a combination of the two.

A method of treating cancer using ketogenic diet, while concurrently subjecting the patient to a hyperbaric, oxygen-enriched environment. Optionally, the hyperbaric, oxygen-enriched environment is 100% oxygen at 2.5 ATA absolute. The treatment may further include administering at least 10% ketone supplementation, such as acetoacetate, adenosine monophosphate kinase, 1,3-butanediol, or ketone ester, to the patient.

The invention relates to a curable sealant composition broadly comprising a resealable, swellable, reactive sealant and free radical initiator; said resealable, swellable reactive sealant comprises monofunctional monomer(s), multifunctional monomer(s), reactive polymer such as unsaturated styrenic block copolymer, swellable additive, and optional components. The monofunctional monomer is a vinyl ester derivative of versatic acid with C9-C12 carbon atoms, or monoacrylate, monomethacrylate, monoacrylamide, or monomethacrylamide. The multifunctional monomer are di-, tri-, tetra-, and / or penta-functional monomers with vinyl, acrylate, methacrylate, acrylamide, or methacrylamide functionality, such as tricyclodecane dimethanol diacrylate, trimethylolpropane trimethacrylate, 1,3-butylene glycol dimethacrylate or a mixture thereof. The reactive unsaturated polymer is a styrenic block copolymer such as SBS, SIS, S-I / B-S, I-SEBS-I, and mixtures of two or more of these. The swellable additive is selected from saturated block copolymers such as SEBS, SEPS, SEEPS, and I-SEBS-I, or a mixture of these. Free radical initiators are preferably peroxides, although others are acceptable.

The invention belongs to the field of human lubricants, and relates to a formula and a preparation method of a human lubricant. The formula comprises the following components in parts by mass: 0.05-0.5 parts of tremella polysaccharide and 0.1-1.5 parts of preservative. The preparation method of the vaginal lubricant comprises the steps that polyacrylamide resin, glycerol, propylene glycol and 1,3-butanediol are sufficiently mixed; an aqueous medium is uniformly mixed; the preservative is added; and the human lubricant is obtained. Compounded agents used by the natural antibacterial lubricant are good in lubrication, mild in property, colorless and odorless, have no adverse effect on a human, have antibacterial and anti-inflammatory action, can be dissolved in water, are convenient to clean, and cannot remain on the surface of human skin, so that the lubricant is safe and effective.

The invention relates to a preparation method for a modified polyacrylamide filtrate reducer for drilling fluid, and belongs to the technical field of petroleum drilling oilfield chemistry high-molecular polymers. The preparation method comprises the following steps: adding acrylamide monomer, 1,3-butylene glycol diacrylate, ethylene thiourea, hydroxy-propyl acrylate, cardanol, trimethylol propyl triacrylate, maleic anhydride, polyvinyl butyral, a chain extender, water, a crosslinking agent, a surfactant and a catalyst into a reactor, uniformly mixing, adding the mixture into a phosphoric acid adjusting system to adjust the pH value to 4-6, feeding inert gas to remove dissolved oxygen in the reaction system; cooling the reaction system, adding an initiating agent, and warming up for polymerization reaction; taking out the obtained jelly reactant, and conducting granulation, stoving and smashing so as to obtain the modified polyacrylamide filtrate reducer. The provided modified polyacrylamide filtrate reducer has the advantages of being good in high-temperature resistance and small in filtrate reduction loss.

Method for the synthesis of a compound of formula H(OCH[CH3]CH2C[O])3—O-A-O—R wherein A is the residue of 1,3-butandiol and R is H or H(OCH[CH3]CH2C[O]3—. The method comprises reacting a cyclic oligomer of (R)-3-hydroxybutyrate consisting of (R)-3-hydroxybutyrate moieties with a 1,3-butandiol in an organic solvent in the presence of Candida antarctica lipase type B in a furan or pyran solvent.

A method is provided for the preparation of high-purity 1,3-butylene glycol from acetaldehyde. In the method, acetaldehyde is condensed in the presence of base to form a mixture of acetaldols, and the acetaldols are then converted to 1,3-butylene glycol by hydrogenation. Chemical treatment and distillation processes are described which provide 1,3-butylene glycol of very high purity.

A color filter ink is adapted to be used to manufacture a color filter by an inkjet method. The color filter ink includes C. I. Pigment Red 254, a dispersion medium, and a pigment derivative. The dispersion medium disperses the C. I. Pigment Red 254 and includes one or more compounds selected from the group consisting of 1,3-butylene glycol diacetate, bis(2-butoxyethyl)ether, 2-(2-methoxy-1-methylethoxy)-1-methylethylacetate, triethylene glycol butylmethylether, and diethylene glycol monobutyl ether acetate. The pigment derivative is represented by a prescribed chemical formula.