10 results about "Polyvinyl pyrrolidone" patented technology

The application discloses a preparation method of fly ash-silane coupling agent composite ceramic membrane, which comprises the following steps: after pretreatment, fly ash is mixed with polyether sulfone, N-methyl pyrrolidone solvent and polyvinyl pyrrolidone to prepare uniform slurry; the slurry is transferred to a spinning kettle; green bodies are prepared after wet spinning and phase conversion; and fly ash ceramic membrane support bodies are prepared through high-temperature gradient sintering. Anhydrous ethanol and deionized water are mixed, hydrochloric acid is added dropwise to adjust the pH value to 4.5, then polyvinyl pyrrolidone is added, stirring is carried out, and then a silane coupling agent is added dropwise to prepare a silane coupling agent coating solution; the ceramic membrane support body is coated by using a pulling method, and is cured in an oven at 80 DEG C, so that the fly ash-silane coupling agent composite ceramic membrane is obtained. The fly ash-silane coupling agent composite ceramic membrane has high oil interception rate, high flux and high stability, and can significantly improve the filtering performance of the support body. Meanwhile, the fly ash-silane coupling agent composite ceramic membrane conforms to the concept of treating waste with waste, reduces the preparation cost, and is suitable for industrial application.

The application provides a low-smoke halogen-free cable sheath material and a preparation method thereof, and belongs to the technical field of high polymer materials. The terminal aluminum-based polyethylene is prepared through coordination chain transfer polymerization, is converted into terminal hydroxyl polyethylene through oxidation hydrolysis, is reacted with sodium hydride to obtain active polyethylene glycol sodium, alkyl sulfonate is used to initiate N -vinyl pyrrolidone cationic addition polymerization to prepare active polyvinyl pyrrolidone cation, and the two are connected through nucleophilic-electrophilic coupling reaction to form an ether bond connected PE-b-PVP block copolymer, and are used as an anchor agent to be blended and melt-extruded with polyolefin resin and phosphazene flame retardant, dipole-dipole interaction between the PVP segment and the phosphazene is utilized to realize in-situ physical enrichment of the flame retardant in the cable sheath. The sheath material has the characteristics of efficient flame retardation, excellent insulation, low smoke density and the like, and can be applied to the fields of medium and high voltage power cables, communication cables, special cables for rail transit and the like.

This invention belongs to the field of pharmaceutical formulations and relates to a compound ophthalmic in-situ gel composition for treating ocular Demodex mite infection, its preparation method, and its application. By weight percentage, the compound ophthalmic in-situ gel composition for treating ocular Demodex mite infection comprises 0.1-2.0% of a nitroimidazole compound, 0.05-3.0% of an isoxazoline compound, 0.1-1.5% of a gelling polymer, 1.0-8.0% of a complex solubilizing system, 0.1-3.0% of pharmaceutically acceptable excipients, and the balance being water. The complex solubilizing system includes polyvinylpyrrolidone and cyclodextrin derivatives. This invention effectively solves the problem of poor solubility of isoxazoline drugs through a complex solubilizing system, and the combination of the two drugs has a significant synergistic acaricidal effect. Combined with a gelling polymer, it can achieve in-situ gelation on the ocular surface, prolong retention, and sustained drug release, with low ocular irritation, providing a highly effective, long-lasting, and safe new local treatment option for Demodex mite-related eye diseases.

The application discloses a method for detecting perchlorate based on a silver nanofilm substrate. The application uses polydiene dimethyl ammonium chloride and sodium diethylthio carbamate as a protective agent, polyvinyl pyrrolidone as a stabilizer, and sodium borohydride-ethylene glycol as a reducing agent to obtain polydiene dimethyl ammonium chloride or diethylthio amino modified silver nanoparticles with high activity through one-pot synthesis or microwave synthesis, which are used as a surface-enhanced Raman scattering substrate for the detection of perchlorate. The perchlorate detection technology provided by the application has the advantages of simple preparation process, green and environmentally-friendly synthesis process, high sensitivity and the like, and provides a new technical path for the accurate detection of perchlorate in water.

The application discloses a method for preparing disease-preventing medium-element water-soluble fertilizer by using Chinese herbal medicine extract, and belongs to the technical field of water-soluble fertilizer. The method comprises the following steps: mixing calcium nitrate (tetrahydrate), anhydrous calcium chloride, magnesium sulfate heptahydrate, magnesium nitrate hexahydrate, anhydrous potassium sulfate, boric acid, white carbon black, citric acid, polyvinyl pyrrolidone and Chinese herbal medicine extract mixture, adding into water and stirring uniformly, discharging and packaging, and the disease-preventing medium-element water-soluble fertilizer is obtained; the Chinese herbal medicine extract mixture is prepared by using Ailanthus altissima swingle fresh leaves, broken powder of Vitex negundo seed, Kigelia japonica flower, dry root of Stemona sessilifolia and Periwinkle whole grass, water extraction, and freeze-drying; by compounding Ailanthus altissima, Vitex negundo, Kigelia japonica, Stemona sessilifolia and Periwinkle five kinds of Chinese herbal medicine extract, multi-target point synergistic inhibition of bacteria is formed, meanwhile, medium-element nutrient supply is met, and the integration of nourishment supply and disease prevention is realized.

The present invention discloses a lyophilized pharmaceutical composition of Sovateltide for parenteral administration. More specifically, the invention discloses a composition comprising Sovateltide stabilized with lactobionic acid 10 and polyvinyl pyrrolidone (Kollidon PF 12), as well as a process for its preparation, which offers improved stability and reduced impurities.

The present application provides a controlled release tablet of Brivaracetam and a preparation method thereof, which comprises: a bilayer tablet core containing Brivaracetam, which is composed of a drug-containing layer and a push layer; and a semi-permeable membrane coating with a drug release hole arranged outside the bilayer tablet core, wherein the drug-containing layer contains an effective dose of Brivaracetam, a sustained-release material I, a sustained-release material II, a binder I and other pharmaceutical excipients; the sustained-release material I is carbomer, the sustained-release material II is selected from any one of hydroxypropyl methyl cellulose, polyethylene oxide and polyvinyl pyrrolidone, and the weight ratio of the sustained-release material II to the sustained-release material I is 1:1-5:1; and the push layer contains a hydrophilic polymer, an osmotic pressure regulator, a binder II and other pharmaceutical excipients. The controlled release tablet of Brivaracetam of the present application has a significant zero-order drug release feature, a stable blood drug concentration, a long-lasting drug effect, and a good medication compliance with once-a-day administration.

The present application relates to the technical field of textile fabric, and discloses a multifunctional composite acrylic fabric and a preparation method thereof, the multifunctional composite acrylic fabric is obtained by treating acrylic fabric with sodium hydroxide solution and finishing liquid in sequence; the finishing liquid is prepared from deionized water, a crosslinking agent, nano silicon dioxide, perfluorohexyl ethyl acrylate, butyl acrylate, polyvinyl pyrrolidone, fatty alcohol polyoxyethylene ether, quaternary ammonium salt modified nano zinc oxide and ammonium persulfate aqueous solution; the quaternary ammonium salt modified nano zinc oxide is prepared from ethanol aqueous solution, nano zinc oxide, gamma-methacryloxypropyl trimethoxysilane, hexadecyl dimethyl allyl ammonium chloride aqueous solution and ammonium persulfate; and the crosslinking agent is prepared from hydroxyl silicone oil, isophorone diisocyanate, dibutyl tin dilaurate catalyst and methanol; the present application has good wear resistance, waterproofness and antibacterial property.

The present application relates to silver nanowire preparation technical field, especially in kind of based on seed control's silver nanowine's preparation method.The present application mixes silver salt solution 1 and ammonia water, carries out complexation reaction, obtains silver ammonia solution;Polyvinyl pyrrolidone solution 1 and silver ammonia solution are mixed after adding formic acid solution, carries out redox reaction, obtains seed solution;Polyvinyl pyrrolidone solution 2, seed solution and sodium chloride solution are mixed after preheating to reaction temperature, and silver salt solution 2 is added, reaction is carried out, and silver nanowine is obtained.The present application utilizes fast nucleation + slow growth mode to prepare silver nanowine, in the preparation seed solution process, formic acid shows moderate reduction rate, can realize continuous uniform nucleation, thereby obtains small, narrow distribution silver seed, shortens the preparation time of seed, controls seed size and quantity.Seed solution is added to improved polyhydric alcohol solution, reduces silver nanoparticle byproduct, improves silver nanowine purity and uniformity.