1691 results about "Polyvinyl pyrrolidone" patented technology

A device and method for the oral transmucosal delivery of active substances to the oral cavity utilizing an unplasticized polyvinyl pyrrolidone polymer (PVP) as the primary mucoadhesive. The device is applied and adheres to the mucosa of the oral cavity without causing side effects or leaving an unpleasant taste. Preferably the device is a bilayer tablet having a mucoadhesive layer and an overlying active substance containing layer. The mucoadhesive layer may contain PVP as the only adhesive or may be combined with other hydrophilic polymeric substances. The active layer also contains a hydrophilic polymer carrier. The layers in the device dissolve and release the active substance to the oral cavity and is particularly adapted for the delivery of substances active in the oral cavity such as breath fresheners and substances to combat dry mouth. It is also useful for the delivery of ionic drugs such as peptides.

The present invention provides a topical gel pharmaceutical formulation of insecticide suitable for treating an ectoparasite in a mammal, comprising: a) about 0.1-10% by weight of an insecticide; b) at least about 75% by weight of an organic solvent selected from the group consisting of a lower alkyl alcohol, a ketone, a glycol and a mixture thereof, wherein the organic solvent contains at least about 40% by weight of the lower alkyl alcohol; and c) at least one polymer selected from the group consisting of a cellulosic polymer, acrylates, methacrylates, and polyvinyl pyrrolidone. The present invention further provides a process of preparing as well as a method of treating ectoparasites in a mammal using the same.

Disclosed are sterile hydrogel compositions comprising polyvinyl alcohol (“PVA”), polyvinyl pyrrolidone (“PVP”), and a polysaccharide, wherein the combined amount of PVA and PVP present in the hydrogel compositions is from about 2% to about 12% weight by volume, based on the total volume of the composition, and wherein the hydrogel compositions has a gel fraction greater than or equal to 97%. Sterile hydrogel products including such sterile hydrogel compositions, and methods of making such sterile hydrogel compositions and sterile hydrogel products.

The present invention relates to a personal care absorbent article comprising at least two substrates each having an internal and external surface, wherein at least one substrate is a fluid permeable bodyside substrate selected from spunbond, meltblown, coform, airlaid, bonded-carded web, spunlace materials and combinations thereof; at least one substrate is an impermeable backsheet; and an absorbent core disposed in between said substrates; wherein at least the external surface of at least one substrate has applied to it a benefit agent selected from an additive composition wherein said additive composition is a polymer dispersion selected from polyolefin dispersions, polyisoprene dispersions, polybutadiene-styrene block copolymer dispersions, latex dispersions, polyvinyl pyrrolidone-styrene copolymer dispersions, polyvinyl alcohol-ethylene copolymer dispersions, and combinations thereof; an enhancement component selected from microparticles, expandable microspheres, fibers, additional polymer dispersions, scents, anti-bacterials, moisturizers, medicaments, soothers and combinations thereof; and combinations thereof.

The polishing slurry of the invention is a polishing slurry for polishing a silicon oxide film on polysilicon, which contains an abrasive, polysilicon polishing inhibitor, and water. As the polishing inhibitor, it is preferable to use (1) a water-soluble polymer having a N-monosubstituted or N,N-disubstituted skeleton substituted by any member selected from the group consisting of acrylamide, methacrylamide, and α-substituted derivatives thereof, (2) polyethylene glycol, (3) an oxyethylene adduct of an acetylene-based diol, (4) a water-soluble organic compound having an acetylene bond, (5) an alkoxylated linear aliphatic alcohol, or (6) a copolymer containing polyvinyl pyrrolidone or vinyl pyrrolidone. There is provided a polishing method which is capable of polishing a silicon oxide film on a polysilicon film at a high speed, and inhibiting the progress of polishing of a polysilicon film in exposed parts in the manufacturing method for a semiconductor.

The decomposer film product has a polymeric decomposer layer, a cover layer for protecting the decomposer film from the surroundings and a releasable support liner, which is removed prior to use. The polymeric decomposer film contains a water-soluble or water-insoluble polymeric adhesive material and a decomposition accelerator, which acts to decompose an effective ingredient, such as a steroid hormone, of a worn or unused transderamal patch, when the effective ingredient releasing layer of the patch adheres to the polymer film, so that the pharmaceutical effective ingredient comes into contact with the decomposition accelerator by diffusion. The decomposition accelerator includes a chemically oxidizing substance, preferably urea peroxide, manganese (III) acetate or iron (III) citrate. The water-insoluble polymeric adhesive material is preferably an acrylates adhesive. The water-soluble polymeric adhesive material is preferably polyvinyl alcohol, polyvinyl pyrrolidone, a cellulose derivative or a polyacrylic acid.

The invention relates to a method for preparing a high-flux composite membrane from a dopamine-modified nanometer material and belongs to the technical field of modification of membrane materials. The method is characterized by comprising the following steps of: forming an active poly-dopamine composite layer on the surfaces of titanium dioxide nanometer grains by utilizing automatic polymerization of dopamine, selecting different concentrations of dopamine-modified titanium dioxide grains, and adding the modified nanometer grains utilized as additives into a membrane casting solution, in which the mass fraction of PVDF (Polyvinylidene Fluoride) is 13% and the mass fraction of PVP (Polyvinyl Pyrrolidone) is 4%, so as to bend and modify according to different proportions, thus obtaining a composite membrane prepared from dopamine-modified nanometer titanium dioxide. The method for preparing the high-flux composite membrane from the dopamine-modified nanometer material, disclosed by the invention, has the advantages that dopamine-modified titanium dioxide can be greatly dispersed in an organic solvent to form a uniform dispersed phase; the additive can be used for effectively improving the hydrophilcity and anti-pollution capability of the high-flux composite membrane; and the dopamine modification method is simple, the condition is gentle, the flux of the prepared membrane is large and the anti-pollution capability is strong.

The invention provides a single phase whitening dentifrice that includes (i) a whitening agent selected from the group consisting of hydrogen peroxide, a bound peroxide and a solid peroxide (ii) an abrasive and (iii) a substantially anhydrous orally acceptable carrier, for example, polyethylene glycol. The bound peroxide may be hydrogen peroxide and a polymer and / or any peroxide compound and a porous cross-linked polymer, such as polymers of polyvinyl pyrrolidone, polyacrylates, a polymethacrylates, and a polyitaconates. The solid peroxide may be sodium perborate or urea peroxide. The invention also provides methods of whitening the tooth surfaces by contacting the surface with the composition.

Provided are a polysulfone type blood-purifying membrane which is improved in blood compatibility and separation properties and less in polyvinyl pyrrolidone eluting in the internal surface of the hollow fiber membrane, as well as a process for producing the same.

The present invention provides a colloidal nanosilver solution which contains nanosilver particles having diameters between 1 nm and 100 nm. The silver content in the colloidal solution is between 0.001% to 0.4% by weight. The colloidal nanosilver solution also contains a gelling agent which includes, but is not limited to, starch or its derivative, cellulose or its derivative, polymer or copolymer of acrylate or acrylate derivative, polyvinyl pyrrolidone, alginic acid, and xanthogenated gel. The present invention also provides a method for making the colloidal nanosilver solution. The colloidal nanosilver solution prepared by this method does not contain any toxic or impure substances.

The invention discloses a medicinal preparation rizatriptan benzoate capsule for treating migraine and a preparation method thereof. Every 10000 capsules are prepared from the following formulation constituents: 29-250g of rizatriptan benzoate, 20-400g of microcrystalline cellulose, 220-1100g of starch, 100-400ml of 10-20% polyvinyl pyrrolidone ethanol solution and 4-30g of magnesium stearate. The invention also provides a preparation method of the rizatriptan benzoate capsule. The capsule of the invention covers the foreign taste of the main medicine; release and absorption of the medicine are accelerated; medical particles in the capsule are not punched or molten, thereby overcoming some defects of tablets; after the capsule is taken orally, the medicine is directly dispersed in the gastrointestinal fluid and is moistened by the gastrointestinal fluid, thus the effective surface area is large; and the medicine has higher dissolving rate in the gastrointestinal fluid, can be better absorbed and has high bioavailability.

The invention relates to a method for preparing a length-diameter-ratio nano-silver wire by a pH-value regulation solvothermal method. The method comprises the following steps of: preparing the following ethylene glycol solution, namely an ethylene glycol solution A of silver nitrate or silver acetate, an ethylene glycol solution B of polyvinyl pyrrolidone (PVP), an ethylene glycol solution C of water-soluble chloride and concentrated acid D; mixing the components according to a certain amount and fully stirring to form a final mixed solution; moving the final mixed solution into a reaction kettle; placing in an oven for reaction for a certain time; taking the reaction kettle out and cooling to room temperature to obtain mother liquid of the nano-silver wire; adding alcohol into the mother liquid for diluting, and removing supernatant liquor to obtain a precipitate; and repeatedly performing centrifugal separation, and thus obtaining nano-silver wire dispersion liquid uniformly dispersed in the alcohol. The method is simple, high in efficiency and low in cost, and can prepare high-quality nano-silver wires within a wider range of reaction condition; and prepared products are high in length-diameter ratio, good in length uniformity and low in impurity content.

A process for making an ink jet ink comprising: a) providing a dispersion containing a pigment, a hydrocarbon carrier, and a polyamine / fatty acid condensation polymer dispersant; b) mixing the pigment dispersion with rigid milling media less than 100 mu m; c) introducing the mixture of step (b) into a mill; d) milling the mixture from step (c) until the pigment particle size is below about 100 nanometers (nm); e) adding to the mixture during or after step d) or f) (below) a stabilizer selected from the group consisting of a polyether polyol; a modified polyester resin; an acrylic polymer; an alkylol ammonium salt of a block copolymer having acidic groups; ethoxylated triethanolamine; a high molecular weight block copolymer having an amine functionality; sorbitan sesquioleate; polyhydroxy stearic acid; butylated polyvinyl pyrrolidone; poly(vinylpyrrolidone / 1-hexadecene); and poly(p-tert-butylstyrene-co-styrene-co-2-sulfoethyl-lithium methacrylate); f) separating the milling media from the mixture milled in step (d); and g) diluting the mixture to obtain an ink jet ink having a pigment concentration suitable for ink jet printers.

The invention relates to a preparation method of a triangular silver nanosheet, which comprises the following steps: firstly, mixing three types of reagents of oxyacid silver, trisodium citrate (Na3C6H5O7.2H2O) and polyvinyl pyrrolidone (PVP) according to a certain molar ratio; stirring for 4-10min at the temperature of 0 DEG C-30 DEG C; adding a proper amount of sodium borohydride (NaBH4) reagent into the mixed system; and then, adding a proper amount of hydrogen peroxide the mass fraction of which is 10%-30% to finally obtain the triangular silver nanosheet the size of which is 50nm-120nm. The method for preparing the triangular silver nanosheet has simple operation and high success ratio and can be carried out at normal temperature.

The invention relates to a fluorocarbon surfactant binary composite foam flooding system. The system is prepared by adopting fluorocarbon surfactant as a foaming agent, adopting a macromolecular compound as a foam stabilizer and adding water; the foaming agent is one or combination of sulphobetaine type fluorocarbon surfactant and amine oxide type fluorocarbon surfactant, or combination of alpha-alkenyl sulfonate and one of sulphobetaine type fluorocarbon surfactant and amine oxide type fluorocarbon surfactant; and the foam stabilizer is partially hydrolyzed polyacrylamide, polyvinyl pyrrolidone K30, polyvinyl pyrrolidone K90 or hydroxyethyl cellulose. An application method comprises that solution of the fluorocarbon surfactant binary composite foam flooding system and nitrogen are alternately injected into a stratum or a rock center so as to improve the recovery rate of crude oil.

A semi-synthetic platelet gel comprising a platelet-rich plasma, at least one platelet activator, and a biocompatible polymer selected from the group comprising carbomers, polyalkylene glycols, poloxamers, polyesters, polyethers, polyanhydrides, polyacrylates, polyvinyl acetates, polyvinyl pyrrolidones, polysaccharides, and derivatives thereof. A method for preparing a semi-synthetic platelet gel comprising the steps of (a) mixing a platelet-rich plasma with at least one platelet activator, and, before the start of clot formation, (b) adding the mixture thus obtained to a biocompatible polymer selected from the group comprising carbomers, polyalkylene glycols, poloxamers, polyesters, polyethers, polyanhydrides, polyacrylates, polyvinyl acetates, polyvinyl pyrrolidones, polysaccharides, and derivatives thereof.

Dental bleaching compositions include a dental bleaching agent, a generally linear high molecular weight (i.e., greater than about 500,000) polyvinyl pyrrolidone (PVP) and / or polyethylene oxide (PEO) tissue adhesion agent included in amount that imparts a high level of adhesiveness, a rheology-modifying agent such as fumed silica or fumed alumina that reduces or eliminates stringiness otherwise caused by the high molecular weight PVP and / or PEO, and a solvent or carrier. Dental bleaching compositions may include carboxypolymethylene instead of or in addition to PVP and / or PEO, wherein the fumed silica or fumed alumina increases long-term rheological stability even in the presence of a high concentration of dental bleaching agent. Dental treatment devices including a barrier layer and a quantity of the dental bleaching composition positioned adjacent to the barrier layer.

The aqueous slurry is useful for chemical mechanical polishing a semiconductor substrate having a tantalum-containing barrier layer and copper interconnects. The slurry includes by weight percent, 0 to 5 oxidizing agent, 0.1 to 25 silica particles, 0.001 to 3 polyvinyl pyrrolidone, 0.02 to 5 weight percent imine barrier removal agent selected from at least one of formamidine, formamidine salts, formamidine derivatives, guanidine, guanidine derivatives, guanidine salts and a mixture thereof, 0.02 to 5 weight percent carbonate, 0.01 to 10 inhibitor for decreasing static etch of the copper interconnects, 0.001 to 10 complexing agent and balance water; and the aqueous slurry having a pH of 9 to 11.

The invention discloses silicon dioxide loaded nano-silver waterborne antibacterial paint and a preparation method thereof, and belongs to the field of chemical paint. The paint is prepared from the following components: water, acrylic resin, polyurethane resin, a porous silicon dioxide loaded nano-silver antibacterial agent, a dispersant, a curing agent, a de-foaming agent, a film-forming auxiliary agent and a flatting agent. According to the silicon dioxide loaded nano-silver waterborne antibacterial paint, nano-silver is loaded in porous silicon dioxide, so that the effect of protecting the nano-silver is realized; a releasing speed of the nano-silver can also be slowed down to a certain extent, so that the antibacterial time of the paint is more durable. A pore channel space is limited and a special preparation process is adopted (under the protection effect of PVP (Polyvinyl Pyrrolidone)), the size of the nano-Ag is controlled to be only 3nm to 5nm, so that the specific surface area of the nano-Ag is greatly increased. Furthermore, a special pore channel of the porous silicon dioxide has a fixation effect on the nano-Ag, so that the nano-Ag is not easy to aggregate and has good dispersity in a solution, and the antibacterial performance of the paint is improved.

The invention provides a method for preparing polyhedral cuprous oxide nanometer granules. The method adopts a chemical solution method to prepare polyhedral cuprous oxide nanometer granules comprising cubes, chamfered cubes, cubic octahedrons, chamfered octahedrons or octahedral series. The method comprises the following concrete steps: copper salt is dissolved in water and stirred at a temperature between 50 and 60 DEG C; polyvinyl pyrrolidone, strong base solution and ascorbic acid solution are orderly added, stirred at a constant temperature between 50 and 60 DEG C and kept for 1 to 3 hours; after the reaction is over, the centrifugation is carried out; and a large amount of the deionized water is used for washing, and the cuprous oxide nanometer granules can be obtained after vacuum drying. By regulating the adding amount of the polyvinyl pyrrolidone, the polyhedral cuprous oxide nanometer granules comprising the cubes, the chamfered cubes, the cubic octahedrons, the chamfered octahedrons or the octahedral series are obtained. The method has the advantages of moderate condition, simple operation, low cost, high yield, controllable shape, and so on.

The invention discloses a method for preparing an aqueous polyurethane / nano titanium dioxide hybrid material and relates to a preparation technology of a modified polyurethane emulsion. The method comprises the following steps of: (1) preparing TBT (Tributyltin) sol; (2) adding polyalcohol and isocyanate which are used as raw material monomers, adding a hydrophilic chain extender, heating up the system to 30-80 DEG C by using N-polyvinyl pyrrolidone as a solvent and then adding a catalyst; (3) after the mixture reacts of 1-6 hours, heating up the system to 60-100 DEG C; continuing to make the mixture react for 1-6 hours, and then cooling to 20-60 DEG C; adding triethylamine used as a salt forming agent, and making the mixture react for 10-60 minutes; dispersing with water by using ethanediamine as a chain extender to obtain an aqueous polyurethane emulsion; maintaining the temperature to 20-50 DEG C, adding a small quantity of gamma-epoxypropyl trimethoxy silane and stirring for 10-90 minutes; adding the TBT sol to the system and dropwise adding a small quantity of hydrochloric acid; and persistently stirring for 12-48 hours to obtain the aqueous polyurethane / nano titanium dioxide hybrid material. The properties such as the weather resistance, the mechanical property, the coating transparency, and the like of the hybrid material are greatly improved.

The invention relates to a method for preparing a core-shell structure metal / polymer nanofiber membrane. The prepared fiber membrane uses a polymer as a nuclear layer and uses a nano-metal as a shell layer; the polymer can be polyvinyl pyrrolidone, polyvinyl alcohol, polyoxyethylene, polylactic acid, polyacrylonitrile, hyaluronic acid, chitosan and the like; the nano-metal shell layer comes from metal salt silver nitrate or copper chloride. The core-shell structure metal / polymer nanofiber is prepared by utilizing the electrospinning technique; by controlling the process parameters, the concentration of polymer, the content of metal salt and the proportioning of solvents, the metal / polymer nanofiber membrane is prepared; the fiber membrane has high application value on tissue engineering, recovery of wound, drug transportation, photoelectricity and the like.

The invention discloses a modified nanometer nulvalent ferric particle and preparing method with grain size at 20-50nm and even grain size at 30-40nm and specific surface at60-70m<2> / g, which comprises the following steps: allocating soluble ferric salt solution and NaBH4 or KBH4 alcohol-water composite solution with bulk rate at 1: 1-20, adding polyvinyl pyrrolidone in the soluble ferric salt solution according to rate, stirring evenly, adding NaBH4 or KBH4 alcohol-water composite solution in the soluble ferric salt solution, stirring continually until the solution becomes black, adopting magnetic method to select nanometer nulvalent ferric particle, washing through distilled water completely, washing through acetone or alcohol then, reserving in the acetone or alcohol.

The invention provides a sustained-release temperature-sensitive blood vessel embolic gel used for treating tumor. The sustained-release blood vessel embolic gel is prepared by entrapping a medicine by using a pharmaceutically acceptable carrier. The medicine is an anti-tumor medicine, and the pharmaceutically acceptable carrier comprises a gel prepared from poloxamer polymer, polyvinyl pyrrolidone, and the like or a composition thereof. The polymer material accounts for 5-65% of a gel mass. The particle size of the gel is in a range of 10nm to 150mum. The embolic agent is liquid gel under normal temperature, and can be used for direct injection through catheter. After injection into body, with the increase of temperature, the liquid gel is rapidly solidified into gel. Also, according to requirements, different medicines can be entrapped, and embolism and medication dual effect can be achieved through local sustained-release. Therefore, the gel provided by the invention can be used as an embolic agent for endovascular treatment, and can be used in various benign and malignant tumor transcatheter arterial chemoembolizations. The preparation method provided by the invention is simple, and is suitable for industrialized productions.

The invention discloses a complex microbial agent for producing soybean paste in Pixian County, which mainly comprises coculture of saccharomyces cerevisiae, candida utilis, lactobacillus plantarum and salt tolerant tetrads, and skim milk powder, glycerin, maltodextrin, trehalose and L-sodium glutamate, or mainly comprises coculture of saccharomyces cerevisiae, candida utilis, lactobacillus plantarum and salt tolerant tetrads, and porous starch, maltodextrin and polyvinyl pyrrolidone. A method for preparing the complex microbial agent for producing soybean paste in Pixian County comprises the following technological steps of: (1) activating and propagating strains; (2) inoculating; (3) co-culturing; and (4) adding a protective agent and drying. By using the complex microbial agent in the preparation of cooked soybean paste, the complex microbial agent maintains the characteristics of traditional soybean paste in Pixian County. Meanwhile, compared with the traditional technology, the complex microbial agent has the advantages of shortening the production period by 1 / 3, improving the amino nitrogen content by 3 to 8 times, improving the volatile aroma content by 2 to 4 times, and ensuring the aflatoxin B1 of 0 to 0.5ppm only.

A thickened composition and process useful for removing paint, comprising: a carbonate such as propylene carbonate or ethylene carbonate, a thickener such as polyvinyl pyrrolidone (PVP), hydrogen peroxide and water. The composition may include additional cosolvents such as glycol ethers and alcohols such as benzyl alcohol, and / or dibasic ester (DBE).

The invention relates to the technical field of battery materials, in particular to a coupled carbon nano tube-graphene composite three-dimensional network structure-coated ternary material and a preparation method thereof. According to the coupled carbon nano tube-graphene composite three-dimensional network structure-coated ternary material, a nickel-cobalt-manganese ternary material, carbon nano tubes and graphene are taken as raw materials; and the ternary material is characterized by being prepared by the following steps: with polyvinyl pyrrolidone as a dispersing agent, through a liquid-phase self-assembling method, simultaneously connecting the graphene and the carbon nano tubes with a silane coupling agent to form a three-dimensional network structure; and evenly dispersing the coupled carbon nano tube-graphene composite material and the nickel-cobalt-manganese ternary material through a physical method, coating the surface of the nickel-cobalt-manganese ternary material, and sintering the nickel-cobalt-manganese ternary material in an inert atmosphere, so as to obtain the evenly coated product. The product provided by the invention has the advantages of high specific discharge capacity, long cycle life and simplicity in preparation process; and large-scale production is easy to realize.

The electrostatic spinning process for preparing low density porous nanometer SnO2 fiber as laser target material is fast, efficient and simple. The electrostatic spinning process includes compound spinning solution with polyvinyl pyrrolidone, absolute ethyl alcohol, tin tetrachloride in certain weight proportion through mixing at room temperature; electrostatic spinning through spraying the spinning solution with spinning jet to an accepting screen 5-30 cm apart from the jet while applying electric field of 0.1-1 kv / cm, controlling the spraying time and the motion of the accepting screen to obtain fiber of different density and deposited in different areas; and roasting at 450-550 deg.c to obtain the nanometer SnO2 fiber.