87 results about "Sodium borohydride" patented technology

The invention discloses a synthesis method of N, N '-bis-(2, 2, 6, 6-tetramethyl-4-piperidyl)-1, 6-hexamethylenediamine, which comprises the following steps: dropwise adding hexamethylenediamine into a mixture of 2, 2, 6, 6-tetramethyl-4-piperidone and an organic solvent, heating to react, cooling after the reaction is completed, adding a sodium borohydride solid into the mixture in batches, and heating to continue the reaction, so as to obtain the N, N'-bis-(2, 2, 6, 6-tetramethyl-4-piperidyl)-1, 6-hexamethylenediamine, namely the N, N '-bis-(2, 2, 6, 6-tetramethyl-4-piperidyl)-1, 6-hexamethylenediamine. After the reaction is finished, decompressing and spin-drying; the preparation method comprises the following steps: adding 1, 2, 6, 6-tetramethyl-4-piperidinyl-1, 6-hexamethylenediamine into an organic solvent, pulping residues, filtering, washing a filter cake with dichloromethane, combining filtrate, and spin-drying to obtain the N, N '-bis-(2, 2, 6, 6-tetramethyl-4-piperidinyl)-1, 6-hexamethylenediamine. The molar ratio of the 2, 2, 6, 6-tetramethyl-4-piperidone to the hexamethylenediamine to the sodium borohydride is (2.0 to 2.1): 1.0: (1.2 to 2.5); sodium borohydride is adopted to replace a traditional noble metal catalyst, high-pressure hydrogenation reaction is avoided, reaction conditions are mild, operation is safe, and cost is low; the purity and the yield of the product are effectively improved.

The invention relates to a diyne functionalized covalent organic framework material as well as a preparation method and application thereof, and the diyne functionalized covalent organic framework material is synthesized by taking 4, 4 ', 4', 4 ''-(pyrene-1, 3, 6, 8-tetrayl) tetraphenylamine and 5, 5 '-(butyl-1, 3-diyne-1, 4-diyl) diisophthalaldehyde as construction units and adopting a Schiff base reaction. The dialkynyl functionalized covalent organic framework material disclosed by the invention has good chemical stability and can be used as a carrier to controllably grow silver nanoparticles through metal coordination to obtain a composite material, and the composite material shows excellent catalytic activity and cycling stability in a 4-nitrophenol reduction reaction catalyzed by sodium borohydride; therefore, the method has important application potential in the fields of environmental restoration, green chemistry and the like.

The present invention relates to a method for preparing a high-purity peramivir intermediate. The method comprises the following steps: Step 1: adding compound II to a reaction kettle, and dropwise adding a sodium borohydride methanol solution; after the dropwise addition is completed, the reaction is stirred at a controlled temperature; purified water and a sodium nitrite solution are added, and the reaction is stirred to prepare compound (III); Step 2: adding acetic anhydride dropwise to compound (III), and the reaction is stirred at a controlled temperature; Step 3: adding a sodium carbonate aqueous solution, stirring, separating the liquids, collecting the organic phase, concentrating under reduced pressure, adding a solvent, stirring and crystallizing, and centrifuging until no obvious liquid flows out; vacuum drying the filter cake to obtain an off-white crude peramivir acetylate (IV); Step 4: refining to obtain an off-white solid peramivir acetylate (IV). #imgabs0#

This invention provides a compound for recognizing chiral amino alcohols, a fluorescent probe, its preparation method, and its application. Naphthol and sodium hydride are weighed and dissolved separately in ultra-dry tetrahydrofuran, mixed, and then reacted with bromomethyl methyl ether. The mixture is extracted with ethyl acetate, and the organic phases are combined to obtain product (R)-1. This product is dissolved in ultra-dry tetrahydrofuran, and n-butyllithium is added. The reaction system changes from colorless to brown, and the reaction is allowed to return to room temperature. Ultra-dry N,N-dimethylformamide solution is then added, and the reaction is quenched by adding saturated ammonium chloride solution under ice-water bath conditions. The product is then extracted with ethyl acetate to obtain product (R)-2. Product (R)-2 is dissolved in a mixed solvent of tetrahydrofuran and anhydrous methanol, and sodium triacetoxyborohydride is added. The product is then extracted with ethyl acetate to obtain reduced product (R)-3. Product (R)-3 is dissolved in a mixed solvent of dichloromethane and anhydrous ethanol, and concentrated hydrochloric acid is added. After the reaction is complete, the reaction is quenched with sodium bicarbonate, and then extracted with dichloromethane to finally obtain compound (R)-4, which recognizes chiral amino alcohols.

The invention discloses a novel nano-enzyme composite material and a preparation method and application thereof.The preparation method of the novel nano-enzyme composite material comprises the following steps that APDA nano-particles, chloroplatinic acid and water are mixed to be uniform, a mixed solution is obtained, a sodium borohydride aqueous solution at the temperature of 0-4 DEG C is dropwise added into the mixed solution at the temperature of 0-4 DEG C, stirring continues to be conducted for 4-6 h at the temperature of 0-4 DEG C, and the nano-enzyme composite material is obtained. The novel nano-enzyme composite material disclosed by the invention has an antioxidant function and an antibacterial property, can synchronously solve the problems of bacterial infection and oxidative stress, and has good photo-thermal stability.

The invention provides a non-noble metal catalyst for hydrogen production through catalytic decomposition of sodium borohydride, and a preparation method and application thereof, and belongs to the technical field of hydrogen production. The cobalt-boron catalyst is loaded on the nitrogen-doped porous carbon material, so that the hydrogen production rate and stability of the catalyst can be greatly improved, the highest hydrogen production rate is 5772 mL * min <-1 > * g <-1 >, and the catalyst can still keep relatively high activity after being recycled for 4 times.

The invention discloses an Nb2O5-loaded PtRu bimetallic catalyst for catalyzing chlorine-containing multi-component VOCs (Volatile Organic Compounds) and a preparation method thereof, and belongs to the field of nano material preparation. A yPtRux / Nb2O5 catalyst is prepared by adopting a reduction method of sodium borohydride (NaBH4) protected by polyvinyl alcohol (PVA), the molar ratio x of Ru to Pt is equal to 0.46-2.03, and the loading capacity y of PtRux is equal to 0.59 wt%-1.17 wt%. The 0.76 PtRu2.03 / Nb2O5 catalyst shows excellent toluene + 1, 2-DCE catalytic oxidation performance: T50% and T90% of toluene are 206 DEG C and 218 DEG C respectively, T50% and T90% of 1, 2-DCE are 315 DEG C and 345 DEG C respectively, and the catalyst has excellent water resistance, chlorine resistance and catalytic stability.

The present invention discloses a method for preparing a highly dispersed five-element high-entropy alloy-loaded carbon sponge absorber. First, a high-energy metal hydride (MOF) rich in zinc-based triazole is synthesized as a precursor. A layered porous carbon sponge is then obtained under inert gas and high-temperature heat treatment conditions. Five metal salts are selected and simultaneously reduced with a saturated sodium borohydride aqueous solution and a hydrogen-argon mixture to obtain a high-entropy alloy loaded on a multilayer carbon network structure. This absorber achieves a reflection loss of 35 dB at 2.7 mm and an effective absorption bandwidth of 9.44 to 13.56 GHz, covering the entire X-band.

The application discloses a kind of core-shell structure Fe 0 The application discloses a preparation method and use method of a core-shell structure Fe 0 @UiO-66-NH2 composite catalyst, the sample of step 2 is added to sodium borohydride (NaBH4) for reduction, and after acid washing, filtration and vacuum drying, the Fe 0 @UiO-66-NH2 composite catalyst is obtained.The purpose of the application is to provide a kind of core-shell structure Fe 0 @UiO-66-NH2 composite photocatalyst preparation method and use method thereof.

The application discloses a preparation method and application of an oxygen vacancy Li2ZrO3 material and belongs to the field of lithium ion batteries. The oxygen vacancy Li2ZrO3 with uniform structure and high ionic conductivity is successfully prepared by using seaweed fiber, hydrochloric acid, ethanol, zirconium chloride, lithium carbonate and sodium borohydride as raw materials. The seaweed fiber is used as a template, so that the defect of excessively large crystal particle size caused by the traditional solid-phase sintering method is avoided to a certain extent; and the oxygen vacancy is manufactured in a certain concentration of sodium borohydride aqueous solution without changing the structure, so that the operation is simple and practical, and the product is controllable.

The invention provides a selenium-doped layered mixed-phase molybdenum disulfide-based piezoelectric catalyst, which is prepared by the following steps: adding selenium powder and sodium borohydride into an ethanol water solution to obtain a selenium-containing solution; adding a molybdenum source and a sulfur source into the selenium-containing solution, and stirring to obtain a reddish brown precursor solution; performing hydrothermal crystallization on the reddish brown precursor solution to obtain a black solid; grinding the black solid into powder, adding into a sodium hydroxide aqueous solution, stirring in a water bath, filtering and collecting the solid; and grinding the collected solid again to obtain the selenium-doped layered mixed-phase molybdenum disulfide-based piezoelectric catalyst. The molybdenum disulfide-based piezoelectric catalyst prepared by the invention is used for performing piezoelectric catalytic degradation on organic wastewater containing antibiotics and / or organic dyes in a microwave environment. According to the molybdenum disulfide-based piezoelectric catalyst, the out-of-plane piezoelectric response is improved, the carrier separation efficiency is improved, the problems that a traditional molybdenum disulfide piezoelectric material is low in active site density and low in carrier separation efficiency are solved, and the molybdenum disulfide-based piezoelectric catalyst can be recycled.

The invention belongs to the field of organic synthesis, and particularly relates to a method for preparing an N, N-difluorobenzenesulfonamide compound under a fluorine-free gas condition. The method comprises the following steps: by taking a benzenesulfonamide compound as an initiator, preparing N-chlorobenzenesulfonamide sodium salt from the benzenesulfonamide compound by using tert-butyl hypochlorite, generating N-fluoro-N-chlorobenzenesulfonamide by using Selectfluor oxidation, and selectively reducing the N-fluoro-N-chlorobenzenesulfonamide into N-fluorobenzenesulfonamide by using sodium borohydride, thereby obtaining the N-fluorobenzenesulfonamide. And finally, carrying out fluorination by using a Selectfluor reagent, so as to generate the target product N, N-difluorobenzenesulfonamide. The method does not need to use highly toxic fluorine gas, the synthesis condition is mild, the separation condition is simple, and the yield is high.

The invention discloses a method for synthesizing jasmine lactone through photocatalytic reaction, and belongs to the field of fine chemicals. The synthesis method comprises the following steps: taking (E)-1, 6-octadiene-3-ketone-2 and iodoacetic acid as raw materials, carrying out photocatalytic reaction to obtain (E)-5-oxo-8-decenoic acid, then reacting with sodium borohydride to obtain (E)-5-hydroxy-8-decenoic acid, and carrying out esterification reaction on a crude product under the catalysis of acid without separation to obtain jasmonlactone. The method for obtaining the jasmine lactone has the advantages of easiness in synthesis of raw materials, mild reaction conditions, low cost and few steps, shows the superiority and simplicity of the synthesis method, and provides a simple way for preparation of the compounds.

The invention discloses a synthesis method of limidoterol, and belongs to the technical field of medicine synthesis. The method comprises the following steps: coupling cyclobutanone oxime and a caffeic acid derivative under the catalysis of ferrous acetylacetonate, a chlorobenzene solvent and the protection of nitrogen to obtain a decarboxylated cyanogen alkylation intermediate; oxidizing the intermediate with m-chloroperoxybenzoic acid in dichloromethane in the presence of sodium carbonate to obtain a vicinal diol monoester intermediate; catalyzing by cobalt chloride in methanol, reducing by sodium borohydride, and protecting by Boc2O to obtain a cyclized precursor; cyclizing the precursor in tetrahydrofuran by using sodium hydride to obtain a cyclized intermediate; and performing deprotection to obtain the limiterol. According to the method, dangerous reagents and processes are not used, the safety is high, and no heavy metal residues exist; the cost is low, precious metals are not needed, the post-treatment operation is simple and convenient, a complex purification process is not needed, and the total yield reaches 21%; process conditions are mild, normal pressure and conventional heating modes are adopted, and industrial production is easy to realize.

The invention belongs to the field of drug synthesis, and particularly relates to a method for preparing a sacubitril intermediate, which is characterized in that an intermediate compound 3 and an organic ammonium salt are used as raw materials and react in the presence of an iridium catalyst and a ligand to generate the sacubitril intermediate. According to the method, the yield and the chiral purity are high, the e.e value is as high as 99.7%, the reaction conditions are mild, and dangerous raw materials such as hydrogen and sodium borohydride are avoided.

The invention relates to an MIL-101 (Cr) assembled metal composite material as well as a preparation method and application thereof. The MIL-101 (Cr) assembled metal composite material is composed of MIL-101 (Cr) and copper. The invention provides a preparation method of an MIL-101 (Cr) assembled metal composite material, which comprises the following steps: dispersing chromium salt and terephthalic acid in water, carrying out hydrothermal crystallization and activation to obtain MIL-101 (Cr) powder, dispersing the MIL-101 (Cr) powder in a solvent to obtain a solution A, adding a copper salt solution, dispersing an intermediate in dichloromethane to obtain a solution B, dispersing sodium borohydride in ethanol to obtain a solution C, adding the solution C into the solution B, and carrying out hydrothermal crystallization and activation to obtain the MIL-101 (Cr) assembled metal composite material. And the MIL-101 (Cr) assembled metal composite material is obtained. The invention provides an application of an MIL-101 (Cr) assembled metal composite material as a catalyst. The problems that an existing copper-based catalyst for catalyzing CO2 conversion is poor in stability and prone to inactivation are solved.

The invention discloses a novel antibacterial material as well as a preparation method, a product and application thereof. The preparation method comprises the following steps: dissolving long-chain alkylamine in an alcohol solution, and marking as a solution A; respectively dissolving zinc nitrate and sodium hydroxide in deionized water, and marking as a solution B; slowly dropwise adding the solution B into the solution A, reacting at normal pressure and low temperature of 0-40 DEG C for 2-30 hours, centrifuging a product, washing with an alcoholic solution for 3-5 times, and drying in a drying oven at the temperature of 60-80 DEG C to obtain a product C; dispersing C into deionized water, uniformly stirring, slowly adding 0.5-1 mmol of a silver salt solution into the solution, and magnetically stirring for 1-2 hours to obtain D; and slowly adding D into a 1M sodium borohydride solution, dipping for 60-90 minutes, centrifuging, and drying in a vacuum oven at 60-80 DEG C for 6-10 hours to obtain the final antibacterial material. The antibacterial material prepared by the invention has a double-effect antibacterial function, and the antibacterial agent prepared by the invention has an excellent antibacterial effect.

This invention discloses Au nanoparticles loaded with bimetallic compounds for photocatalysis and their preparation method, belonging to the field of photocatalytic materials technology. Preparation steps: S1: Tetrachloroauric acid, quaternary ammonium salt, and citric acid are added to a sodium borohydride solution and stirred at 25-120℃ for 1-3 hours to obtain solution A; solution B is prepared containing quaternary ammonium salt, tetrachloroauric acid, ascorbic acid, silver nitrate, and hydrochloric acid; solutions A and B are mixed and stirred at 25-50℃ for 1-15 hours to obtain Au nanoparticles; S2: Solution C is prepared containing quaternary ammonium salt, a first metal source, and ascorbic acid; solution D is prepared containing quaternary ammonium salt, a second metal source, NaOH, and ascorbic acid; Au nanoparticles are mixed with solution C and reacted at 40-80℃ for 1-5 hours; then the supernatant is removed by centrifugation, and solution D is added again, reacting for 1-5 hours to obtain Au nanoparticles loaded with bimetallic compounds. This invention enables controllable nanoparticle structure and allows for metal loading at different sites by adjusting synthesis parameters.

This invention discloses a binary cocrystalline sugar alcohol sodium borohydride blend hydrogen-producing material. The ratio of sodium borohydride to the binary cocrystalline sugar alcohol sodium borohydride blend hydrogen-producing material is 1:0.3-2 (molar ratio). The binary cocrystalline sugar alcohol is a blend of two selected from xylitol, erythritol, sorbitol, or arabinol, and the melting range of the binary cocrystalline sugar alcohol is 80-94℃. In this solution, the binary cocrystalline sugar alcohol has a lower melting point than the single sugar alcohol, reducing the initial hydrogen release temperature and increasing the hydrogen release yield. The resulting hydrogen-producing material has an initial hydrogen release temperature below 70℃ and a hydrogen release yield above 2.1 wt.%, with a maximum of 4.5 wt.%.

The present disclosure provides methods, compounds, and compositions for treating industrial streams. A method of treating a stream may include adding a scavenger to the stream and adding an amine to the stream. The stream may include an acid gas and / or a carbonyl-containing compound. The scavenger may include, for example, sodium borohydride, hydroxylamine sulfate, acetaldehyde oxime, sodium cyanoborohydride, or any combination thereof. The amine may include, for example, ethylene diamine, ethyl ethanolamine, diethyl monoethanolamine, or any combination thereof.

The invention discloses grape pomace pretreatment liquid and a method for preparing microcrystalline cellulose from grape pomace. The grape pomace pretreatment liquid is prepared from laccase, polygalacturonase, acetosyringone, sodium dihydrogen phosphate, disodium hydrogen phosphate, dithiothreitol, fatty alcohol-polyoxyethylene ether, sorbitol and the balance of water. The method for preparing the microcrystalline cellulose from the grape pomace comprises the following steps: S1, cleaning the grape pomace with normal hexane, then cleaning with water, drying and crushing; s2, carrying out mixed reaction with the pretreatment liquid, and then separating out pretreatment residues; s3, adding a sodium carbonate solution for premixing, then adding a tetramethylammonium hydroxide solution and a sodium borohydride solution, and filtering after reaction to obtain filter residues; s4, adding a citric acid solution, adding carboxymethyl chitosan, adsorbing, and filtering to obtain cellulose residues; and S5, hydrolyzing and depolymerizing by using dilute acid, neutralizing, separating and washing an acidolysis product, and drying to obtain the microcrystalline cellulose. According to the method, impurity components which are difficult to treat in the grape pomace can be overcome, impurity removal and purification are completed, cellulose is reserved to the maximum extent, loss is reduced, and the yield is remarkably increased while high-purity microcrystalline cellulose is obtained.

The invention relates to a method for preparing 1, 4-butanediamine from succinonitrile, which comprises the following steps: S1, adding succinonitrile, Raney nickel, alkali and an alcohol solvent into a system under a nitrogen condition, and heating to 30-100 DEG C; s2, adding sodium borohydride into the system, and carrying out gas phase detection on the reaction process; after the reaction is completed, stopping the reaction, filtering and rectifying; and when the GC purity of the distillate reaches 99% or above, receiving the product. The invention provides a scheme for preparing the 1, 4-butanediamine, which is mild in reaction condition, easy to operate and relatively low in cost, and has a great industrial application prospect.

The present invention discloses a preparation method of Cu nanoflowers and their application in the detection of cola sugar content. The preparation process of Cu elemental nanoflowers includes dispersing the prefabricated powder in a copper sulfate solution, stirring evenly, adding a sodium borohydride solution with a specified concentration, and reacting at room temperature for 2-3 hours. In addition, the present invention also discloses a method for detecting cola sugar content by modifying a working electrode with Cu elemental nanoflowers. Its chronoamperometric response signal decreases linearly as the cola concentration is diluted. The concentration of sugar in cola can be calculated from the obtained linear fitting equation. The detection method provided by the present invention has low cost and high selectivity, and has high commercial value.

The invention discloses a high-efficiency rotigotine preparation process which comprises the following steps: dissolving sodium triacetoxyborohydride in a reaction solvent, adding 2-thiopheneethylamine while stirring, dropwise adding a dichloromethane solution of 5-methoxy-2-tetralone, continuously reacting, and carrying out post-treatment to obtain N-(1, 2, 3, 4-tetramethyl-4-piperidine)-1, 2, 3, 4-tetramethyl-4-piperidine. The preparation method comprises the following steps: adding 2, 2, 4-tetrahydro-5-methoxy-2-naphthyl)-2-thiophene ethylamine; dissolving L-DTTA and L-DBTA in ethanol and a water solvent, adding into the product, carrying out a reflux reaction, and recrystallizing to obtain a single-configuration resolution salt; the preparation method comprises the following steps: adding sodium triacetoxyborohydride into a reaction kettle, carrying out product alkalization, carrying out methyl tertiary ether extraction, concentrating an organic layer until the organic layer is dry, dissolving with dichloromethane, adding sodium triacetoxyborohydride, dropwise adding propionaldehyde, continuously carrying out stirring reaction after dropwise adding, after the reaction is finished, concentrating until no liquid drop exists, and carrying out post-treatment to obtain (S)-5-methoxyrotigotine; and dropwise adding HBr, and recrystallizing with n-hexane to obtain rotigotine. According to the present invention, the STAB-mediated continuous reductive amination is adopted to replace the high pressure hydrogenation, and the L-DTTA / L-DBTA composite resolution system is designed to improve the chiral selectivity, such that the process is simplified, and the cost is reduced.

The application discloses a method for catalyzing sodium borohydride to produce hydrogen at low temperature, which is characterized by using natural flavonoids (including flavone, flavonol, isoflavone and the like) as a catalyst, using methanol or a mixture of methanol and water as a reaction solvent, using NaBH4 as a raw material for hydrogen production, and performing alcoholysis of NaBH4 to produce hydrogen. The catalyst used in the application is abundant in source and low in price, can catalyze sodium borohydride to produce hydrogen through alcoholysis at a wide reaction temperature range, has stable catalytic performance, high hydrogen production rate, good catalytic durability and reusability, and has important significance for the application and popularization of sodium borohydride in the field of hydrogen production.

This invention discloses an FA / Au@COF(Fe) composite system, its preparation method, and its applications. The composite system comprises folic acid and Au@COF(Fe), wherein Au@COF(Fe) is composed of COF(Fe) and Au NP. The preparation method of the FA / Au@COF(Fe) composite system is as follows: Au solution and sodium borohydride are added to a solution of iron porphyrin COF and reacted to obtain Au@COF(Fe). Au@COF(Fe) is then dispersed in an alcohol solvent and added to a solution containing folic acid, and reacted to obtain FA / Au@COF(Fe). The preparation method of this invention is simple, inexpensive, and highly effective. This Au@COF(Fe) composite system exhibits catalase-like activity, enabling rapid colorimetric detection of H2O2 and tumor cells, demonstrating excellent detection performance and suitable for large-scale production and utilization.

The application discloses a preparation method of a cotton fabric loaded with cinnamaldehyde Schiff base and application thereof, and comprises the following steps of pretreatment of the cotton fabric: soaking the cotton fabric in a sodium periodate aqueous solution, avoiding light reaction, washing, and preparing an oxidized cotton fabric; preparation of the cotton fabric loaded with cinnamaldehyde Schiff base: soaking the oxidized cotton fabric in a polyethyleneimine ethanol solution, washing, then soaking in a sodium borohydride ethanol solution, washing, finally stirring and reacting in a cinnamaldehyde ethanol solution, taking out, washing, drying, and obtaining the cotton fabric loaded with cinnamaldehyde Schiff base. The cotton fabric has the advantages of absorbing ultraviolet light and near-infrared light, antibacterial property, improved hydrophobicity of the cotton fabric, and improved wrinkle resistance of the cotton fabric.

The invention belongs to the technical field of seawater fuel cell power generation, and particularly relates to a water circulation fuel cell power system based on seawater hydrogen production and a ship. Comprising a seawater pretreatment unit used for receiving seawater and removing impurities in the seawater; the fuel supply and mixing unit is connected with the seawater pretreatment unit and is used for mixing NaBH4 and seawater to form hydrogen fuel; the hydrogen fuel cell unit is connected with the fuel supplying and mixing unit and is used for generating hydrogen through hydrolysis reaction, converting the hydrogen into direct current and generating circulating water; the circulating unit is respectively connected with the hydrogen fuel cell unit and the fuel supplying and mixing unit and is used for feeding circulating water into the fuel supplying and mixing unit; and the power unit is connected with the hydrogen fuel cell unit and used for providing power for the ship. The seawater directly participates in the hydrolysis reaction of the sodium borohydride to start the system, and the water generated by the fuel cell is recycled, so that a'water-hydrogen-electricity 'closed loop is realized, and the energy density and the space utilization rate of the ship are improved.

A method of hydrogen generation may include contacting sodium borohydride (NaBH4) and water in the presence of a catalyst including a nanocomposite comprising graphitic C3N4, MO3, and MgAl2O4 in a mass relationship to each other in a range of from 5 to 15:2 to 7:75 to 95, at a temperature in a range of from 10 to 80° C., thereby catalyzing the hydrogen generation at a hydrogen generation rate in a range of from 2750 to 6000 mL / (min·g).