2005 results about "Self-assembly" patented technology

The present invention discloses a self-assembled monolayer hole transport material based on an alkyl polyphosphate anchoring group, a synthesis method thereof, and an application in an inverted perovskite solar cell. The present invention uses carbazole or 3,6-diphenylcarbazole with good hole transport properties as a parent core, and achieves complete coverage and stable self-assembly of the material on the substrate surface by improving the anchoring group from traditional alkyl monophosphate to alkyl diphosphate and triphosphate. The synthesis method of the present invention is simple and the synthesis cost is low. The prepared material can achieve the dual functions of hole transport and perovskite interface passivation, while enhancing the self-assembly strength and stability. When the material is used as a hole transport layer in an inverted perovskite solar cell, a photoelectric conversion efficiency of >20% can be obtained without doping, and the material has broad application prospects.

The invention discloses a thiapyran molecule modified solar cell and a preparation method thereof. The cell sequentially comprises an ITO (Indium Tin Oxide) conductive glass layer, a 4-aminotetrahydro-2H-thiapyran-1, 1-dioxide hydrochloride modified [4-(3, 6-dimethoxy-9H-carbazole-9-yl) butyl] phosphonic acid hole transport layer, a Cs0.05 (FA < 0.77 > MA < 0.23 >) < 0.95 > Pb < (I < 0.77 > Br < 0.23 >) 3 wide-band gap perovskite thin film, a phenethyl ammonium iodide passivation layer, an electron transport layer of [6, 6]-phenyl-C61-butyric acid isomethyl ester, a 2, 9-dimethyl-4, 6, 7-tetrahydro-2H-thiapyran-1, 1-dioxide hydrochloride modified [4-(3, 6-dimethoxy-9H-carbazole-9-yl) butyl] the hole barrier layer is made of 1, 7-biphenyl-1, 10-phenanthroline; the electrode layer is made of metal Ag; according to the scheme, the hole transport layer is modified through thiapyran molecules, agglomeration of the hole transport layer is relieved, and a more compact and more uniform self-assembled single layer is generated by inducing favorable crystal orientation. A good bottom interface is obtained based on thiapyran molecule modification, and ordered growth of high-quality perovskite crystal grains is promoted. In addition, the energy level of the hole transport layer is effectively adjusted through thiapyran molecule treatment, and the extraction and transmission of carriers by the hole transport layer are enhanced.

This invention discloses a fluorene-based organic small molecule hole transport material and its applications. The general structural formula of the fluorene-based organic small molecule hole transport material is as follows: where n = 1-4, and R represents the hole transport capacity. This fluorene-based organic small molecule hole transport material is used as an undoped hole transport material in perovskite solar cell devices. By introducing dicarboxylic acid groups onto the fluorene-based organic small molecule hole transport material, when used in an inverted perovskite solar cell device, it can form chemical bonds with the hydroxyl groups of the glass conductive substrate, forming a directionally aligned self-assembled layer on the surface of the glass conductive substrate. This effectively improves the charge transport capability at the interface and increases the photoelectric conversion efficiency of the perovskite solar cell device. Furthermore, since this perovskite solar cell device does not contain lithium salts, it exhibits high water and oxygen stability. In addition, the synthesis process of this fluorene-based organic small molecule hole transport material is simple, and the raw materials are inexpensive and readily available, making it highly valuable for practical applications.

Embodiments of improved methods are provided to form ordered structures on a surface of a substrate using direct self-assembly (DSA) of ionic liquid crystals (ILCs). More specifically, various embodiments of methods are provided to control the pitch of a layered structure formed on a substrate surface via self-assembly of ILCs having cation head groups, alkyl tail groups and anions. In the embodiments disclosed herein, the pitch of the layered structure is controlled by: (a) controlling the cation / anion charge ratio of the cation head groups and anions included within the ILCs, and / or (b) adding an ionic liquid to a solution comprising the ILCs.

The invention relates to the technical field of soil conditioners, and particularly discloses an intelligent controlled-release core-shell alginate soil conditioner and a preparation method thereof.The conditioner is of a core-shell-layer three-layer structure and comprises a core layer, a middle shell layer and an outer layer, the three layers account for 30%, 40% and 30% of the total weight respectively, and the core layer mainly comprises improved alginate and nutrients; the middle shell layer mainly comprises chitosan and a microbial preparation; and the outer layer mainly comprises modified charcoal and magnetic nano # imgabs0 #. The preparation method comprises the four steps of core layer preparation, middle shell layer coating, outer layer coating and forming post-treatment, and multiple functions of accurate nutrient supply, efficient heavy metal fixation and soil microenvironment regulation and control are achieved through a core-shell-layer three-layer structure design and a pH / temperature / microorganism triple response mechanism by adopting a coaxial electronic injection and layer-by-layer self-assembly technology; the fertilizer has a remarkable improvement effect on sandy soil and saline-alkali soil, and the organic matter increasing rate reaches 40%.

The invention relates to the field of ultrasonic sensors, provides an ultrasonic sensor and a preparation method thereof, an ultrasonic fingerprint module and electronic equipment, and at least facilitates improvement of the performance of the ultrasonic sensor. The preparation method comprises the following steps: forming a bottom electrode layer on a substrate; forming a piezoelectric layer on the bottom electrode layer; a top electrode is formed on the piezoelectric layer, and the top electrode layer is prepared through the steps that the surface of the piezoelectric layer is treated, so that the surface of the piezoelectric layer has hydrophilicity; carrying out silanization treatment on the piezoelectric layer to form a self-assembled molecular layer; soaking the substrate subjected to silanization treatment in a pre-polymerization solution, so that the self-assembled molecular layer and monomers in the pre-polymerization solution are polymerized to form an adhesion layer; forming a catalyst layer on the adhesion layer; the substrate with the catalyst layer is placed in a chemical plating tank, so that a catalyst in the catalyst layer catalyzes metal ions in the chemical plating tank to form a metal layer, and the adhesion layer and the metal layer form a top electrode layer; and forming a protection layer on the top electrode layer.

The present invention relates to the field of biomedical materials. Particularly provided is a DNA-silk fibroin composite hydrogel microsphere. The DNA-silk fibroin composite hydrogel microsphere is prepared from DNA and silk fibroin on the basis of the micro-fluidic technology by means of combination of self-assembly physical crosslinking and photo-crosslinking. The introduction of a silk fibroin network into the composite hydrogel microsphere can provide mechanical performance for a DNA hydrogel network and reduce the production cost. RGD can remarkably improve the cell loading capability of the microsphere. The hydrogel microsphere can simulate a microenvironment of cartilage tissue by means of three-dimensional loading of high-density cells, so as to enhance substance exchange and signaling between cells, and more effectively promote the proliferation and adhesion of bone marrow mesenchymal stem cells and regulating the chondrogenic differentiation, thus promoting cartilage regeneration and repair, and providing an available material for preparing medicaments or medical instruments for cartilage defect repair.

The invention provides high-activity contact type silver powder for photovoltaic conductive silver paste, a preparation method of the high-activity contact type silver powder and the photovoltaic conductive silver paste, and belongs to the technical field of photovoltaic materials. The high-activity contact type silver powder comprises net-shaped polycrystalline spherical silver powder and an active layer wrapping the surface of the net-shaped polycrystalline spherical silver powder. Wherein the reticular polycrystalline spherical silver powder is a spherical aggregate formed by stacking and self-assembling flaky particles with the particle size of 200-600 nm, and the reticular polycrystalline spherical silver powder is of a porous structure; and the active layer is an organic amine compound. The silver powder disclosed by the invention has good conductivity after being sintered, the adhesive force of a fine grid is relatively high, and the assembly has relatively high power output.

The invention belongs to the photovoltaic field, and particularly relates to a self-assembled monolayer (SAMs), a perovskite solar cell and a preparation method. The self-assembled monolayer comprises a self-assembled monolayer molecule and a thiophene organic matter. The thiophene organic matter forms a frame structure after SAMs film forming, the stability of SAMs can be improved, meanwhile, the carrier transport efficiency of a hole transport layer is improved through the pi-pi conjugation effect, and the performance of a device is improved.

The disclosed subject matter relates compounds of structure (I), and polymers of structure (II) having a polydispersity ranging from 1 to about 1.1, compositions comprising said polymers and a spin casting solvent, the process of forming a pinning layer selectively on metal with said composition and the process of using said pinning layers to affect chemoepitaxy directed self-assembly of an overlying block copolymer, and the subsequent process of pattern transfer of this self-assembled layer into a substrate by etching.

The present disclosure provides an alignment method and application of a cyanobiphenyl liquid crystal composite doped with an organic donor material. The organic small molecule is doped in the host cyanobiphenyl liquid crystal, and the small molecule donor / cyanobiphenyl liquid crystal mixture is directionally induced to assemble by virtue of the large surface energy difference between the superhydrophobic structured substrate and the superhydrophilic flat substrate. The liquid crystal molecules form a uniform arrangement under the action of the liquid bridge, driving the self-assembly of the small molecule donor to be embedded in the cyanobiphenyl liquid crystal, forming a structure of electron donor-donor, enhancing the conductivity of the liquid crystal composite device, studying the influence of the surface tension of the solvent on the performance of the composite, and giving a direction for the selection of the solvent. Compared with the methods of inducing the alignment of liquid crystal molecules and donor small molecules by using electric fields, magnetic fields, photolithography, capillary methods, etc., this method is simpler and more feasible, easy to transfer, the circuit pattern is easy to design, and has good stability.

The invention provides a coordination nano assembly of chiral cyclopeptide and manganese ions as well as a preparation method and application of the coordination nano assembly. According to the method, a manganese superoxide dismutase protein structural domain and a unique tumor microenvironment of melanoma high tyrosinase are combined, and polypeptide sequences L-YD-hL-DD-h, L-YL-HL-DL-H and D-yD-hD-dD-h with different chirality are designed for the first time; the chirality of the polypeptide is regulated and controlled, the in-vivo circulation stability and the cell entry efficiency of the nano assembly are improved, the coordination self-assembly of manganese and different chiral cyclopeptides is realized, and the in-situ oxidation of an in-vivo tumor microenvironment is simulated for photo-thermal therapy and cell membrane coating. The method disclosed by the invention is simple, mild in experimental condition and easy to operate, the prepared cell membrane coated nano assembly not only has long circulation stability and high cell entry efficiency, but also can realize mild photo-thermal therapy through in-situ oxidation, releases manganese ions to activate a CGAS-STING pathway for immunotherapy of tumors, and has a wide application prospect. The potential application value is realized in the field of combined treatment of tumors.

The invention provides an ER targeting self-assembly AIE probe with cascade ROS / RNS generation performance, and belongs to the technical field of material chemistry, the probe is composed of four units: 1) an AIE photosensitizer OTBS used for generating ROS; 2) deriving peptide FFVLK from beta amyloid protein, and promoting the self-assembly of the peptide to form a nanofiber with a beta-sheet structure; (3) an oligomerization arginine unit RRRR which is used as an NO donor; and 4) ER targeting signal peptide KDEL to endow ER with targeting ability. Based on ER targeting and a self-assembly process, the self-assembly AIE probe is subjected to ER in-situ self-assembly in cells to form nanofibers, ROS / RNS is generated in a cascading manner under illumination, and strong ICD is induced. In addition, the tumor residence time of the photosensitizer is prolonged due to the formation of the nanofibers, and the treatment effect is further improved. The invention provides a new thought for the design of a novel light-operated II-type ICD inducer.

The invention relates to a structural design, synthesis and application of a biomass carbon dot modified poly L-cysteine-S-S-carboxylic acid amphiphilic polypeptide. The invention provides a structural design, synthesis and application of poly (L-cysteine-S-S-carboxylic acid) amphiphilic polypeptide (P-L-cys) modified by biomass carbon dots (CDs). Comprising synthesis of P-L-cys which contains hydrophobic groups, provides hydrophilic and functionalized carboxyl and provides reduction response by disulfide bonds, synthesis of CDs and CDs modified P-L-cys (CDs (at) P-L-cys), and the macroscopic performance change of the polypeptide is explored from regulation factors of a polypeptide secondary structure and a self-assembly nanostructure assembly mechanism. The P-L-cys and the CDs (at) P-L-cys prepared by the invention have functionalization, fluorescence imaging and dual-response drug release and have particle sizes suitable for drug delivery and enrichment, and the CDs also provide a photo-thermal and photodynamic synergistic treatment effect and have good application prospects in the fields of drug delivery, cancer resistance and the like.

The invention belongs to the field of micro-nano structures, and relates to a preparation method of a nano needle tip split ring 3D structure periodic array. According to the method, after a reflecting layer and a supporting layer are deposited on a silicon substrate, polystyrene nanospheres are self-assembled, the volume of the nanospheres is reduced through reactive ion etching, then two times of inclined magnetron sputtering are carried out, deposited precious metal is etched through a reactive ion etching machine, and the silicon substrate is obtained. And removing the nanosphere mask to obtain the 3D structure periodic array of the nanotip split ring. The method has the characteristics of simple preparation process, good uniformity, high order degree and strong repeatability, and has wide application potential in the fields of SERS (Surface Enhanced Raman Scattering), photoelectric property detection and the like.

The invention discloses an acid responsive nanoprobe as well as preparation and anti-tumor application thereof. The nanoprobe has a core-shell structure, takes a nanoparticle self-assembled by a polycation aggregation-induced emission (AIE) photosensitizer and functional nucleic acid as a core, and takes a hyaluronic acid modified metal polyphenol network as a shell. The nanoprobe utilizes the acid responsiveness and broad-spectrum absorption performance of the metal polyphenol network and the diagnosis and treatment advantages of the polycation AIE photosensitizer to realize the acid responsiveness'switch 'controllable diagnosis and treatment of the tumor nanoprobe. In a neutral environment, the fluorescence is weak, the generation of ROS is less, and the background noise signal of the nanoprobe and the toxicity of non-targeted tissues are reduced; in an acid environment, fluorescence is enhanced, the ROS yield is improved, and the treatment efficiency and the curative effect monitoring accuracy are improved. The nano diagnosis and treatment probe is ingenious in design and simple to prepare, and can realize PDT and gene therapy synergistic anti-tumor, in-situ real-time report of early tumor treatment effect and assistance in precise cancer treatment.

The invention belongs to the technical field of immunoassay and biosensing detection, and particularly relates to a preparation method and application of an antibiotic electrochemical luminescence sensor based on a double-enhancement strategy. According to the invention, a bifunctional metal organic gel is used as a substrate, a graphite-phase carbon nitride quantum dot is used as a luminous body, and a self-assembly split aptamer walker is combined to construct the electrochemical luminescence sensor for sensitive detection of antibiotics. The sensor has the advantages of extremely high specificity and sensitivity, wide detection range, low detection limit and strong anti-interference performance, and has important scientific significance and application value in detection of antibiotic residues in the environment.

The invention provides a perovskite solar cell, a preparation method thereof and a photovoltaic module. The perovskite solar cell comprises a first electrode, a hole transport layer, a perovskite layer, an electron transport layer and a second electrode which are stacked in sequence. The material of the hole transport layer comprises a biomolecular material which is fixed on a self-assembly monomolecular layer material through an intermolecular force, and the biomolecular material comprises one or more of guanine, adenine, thymine, uracil, cytosine, hydroxymethylcytosine, xanthine, hypoxanthine, 6-mercaptopurine and corrin. According to the perovskite cell provided by the invention, the biomolecular material with a plurality of nitrogen heterocyclic structures and amino groups is added to generate multipoint hydrogen-bond interaction and pi-pi accumulation with the tail end of the SAM, so that the orderliness of molecular arrangement is improved, and the dipole direction and strength of the whole interface are regulated and controlled; and a coordination bond or hydrogen bond network is formed by the coordination compound and uncoordinated cations or anions in perovskite, so that interface defects are effectively passivated, and the thermal stability and the humid and hot life of a device are enhanced.

The invention relates to the technical field of organic light-emitting display, and discloses a preparation method of a silicon-based OLED micro-display, which comprises the following steps: S1, cleaning a silicon-based CMOS driving circuit substrate containing an electrode, and removing surface pollutants; s2, performing plasma surface treatment on the substrate through argon, nitrogen or oxygen; s3, forming a molecular layer on the surface of the electrode through a self-assembly monomolecular layer technology; s4, depositing a protective film material on the surface of the treated electrode through a solution deposition method; s5, the protective film is removed through laser etching, and the surface of the electrode is exposed; and S6, cleaning and patterning the electrode by using a developing solution, and further carrying out electrode welding. The surface of the electrode is treated by adopting a self-assembly monomolecular layer technology, and the polarity and the adhesive force of the surface of the electrode can be remarkably enhanced through modification of an amino silane solution, so that the bonding strength among all layers of materials is improved.

The invention relates to the technical field of road construction and maintenance, and discloses a multi-polymer modified emulsified asphalt in-situ cold recycling mixture and a preparation process thereof, the multi-polymer modified emulsified asphalt in-situ cold recycling mixture comprises the following components by weight: 600-680 parts of nano hybrid emulsified asphalt; 250 to 350 parts of plasma activated recycled aggregate; 15 to 30 parts of a microcapsule phase change catalyst; 5 to 10 parts of bio-based interface reinforcing fiber; and 3-8 parts of a rare earth doped curing accelerator. According to the invention, through multi-technology cross-scale fusion of a quaternary polymer rigid-flexible synergistic system, a gradient emulsification-vacuum self-assembly process, double-shell intelligent catalytic release and rare earth gradient distribution-magnetic field induced fiber arrangement, the bottlenecks of unbalanced high and low temperature performance, easy interface stripping, poor aging resistance, extensive process regulation and control and the like of a traditional asphalt material are overcome; and the strength and toughness-durability-self-adaption performance synergistic jump is realized.

The invention discloses a method for detecting acrylamide in coffee based on colorimetric and photo-thermal dual modes of MXene / MOFs nano-enzyme, and belongs to the technical field of chemical analysis and detection.According to the method, LiF and HCl are used for etching Ti3AlC2 to obtain Mxene, a solvothermal method is adopted for synthesizing Mn / Fe-MIL-NH2, Mxene coated Mn / Fe-MIL-NH2 nano-enzyme is obtained in a self-assembly mode, the Mxene coated Mn / Fe-MIL-NH2 nano-enzyme has peroxidase-like activity and photo-thermal performance, and the Mxene coated Mn / Fe-MIL-NH2 nano-enzyme can be used for detecting acrylamide in coffee in the colorimetric and photo-thermal dual modes. Under irradiation of near-infrared light 808 nm, peroxidase-like activity of the Mxene-coated Mn / Fe-MIL-NH2 nano-enzyme is improved, due to addition of acrylamide, the speed of oxidizing a substrate TMB by the Mxene-coated Mn / Fe-MIL-NH2 nano-enzyme is increased, meanwhile, the temperature of the oxidized TMB with photosensitive performance is also increased, and the method has the advantages of being high in sensitivity, high in specificity, easy to operate, rapid and the like.

The invention provides a method for visually and rapidly detecting carbosulfan pesticide by using medium-entropy nano-enzyme and application of the medium-entropy nano-enzyme, and belongs to the technical field of analytical chemistry. On the basis of a metal ligand cross-linking strategy, the medium-entropy nano-enzyme FeCeCu MEzymes is synthesized through self-assembly of the chelating ability of dopamine phenolic hydroxyl and multi-metal ions of Fe < 3 + >, Ce < 3 + > and Cu < 2 + >, and the medium-entropy nano-enzyme FeCeCu MEzymes sensor is designed to be combined with a smart phone to realize rapid visual detection of carbosulfan; the rapid and visual carbosulfan detection method provided by the invention has the advantages of rapidness, high sensitivity, good selectivity, visual detection result and the like, and is simple and easy to operate and relatively low in cost.

The invention belongs to the technical field of preparation of polypeptides, and particularly relates to a self-assembled polypeptide capable of responding to alkaline phosphatase and degrading Neuropilin-1 as well as a preparation method and application of the self-assembled polypeptide. The self-assembled polypeptide (formula I) provided by the invention has a self-assembly starting unit 'GNNQQNY (SEQ ID NO: 1)', can be self-assembled in vitro, and can form nanofibers after responding to alkaline phosphatase, so that not only can the critical self-assembly concentration of the polypeptide be reduced, but also the binding capacity with target protein can be improved. The material can degrade NRP1 on the surfaces of tumor cells and Treg cells, and has huge potential in promoting immunotherapy of tumors.

The invention relates to the technical field of all-solid-state batteries, in particular to air-stable argyrodite type sulfide electrolyte, a preparation method thereof and an all-solid-state battery. The air-stable argyrodite type sulfide electrolyte provided by the invention comprises a sulfide solid electrolyte and a protective layer formed by self-assembly of organic molecules on the surface of the sulfide solid electrolyte, wherein the sulfide solid electrolyte is argyrodite type sulfide solid electrolyte, the general formula of the sulfide solid electrolyte is Li < 7-a > PS < 6-a > X , X is halogen, and a is more than 0 and less than 2; the organic molecule is at least one of 1-methoxyhexane, 2-heptanone, 3-chloropropanol, 4-chlorobenzyl mercaptan, n-amylamine, 5-chloromethyl-1, 3-benzodioxole, chlorophenylmethane and ethylbenzene, and the organic molecule is at least one of 1-methoxyhexane, 2-heptanone, 3-chloropropanol, 4-chlorobenzyl mercaptan, n-amylamine, 5-chloromethyl-1, 3-benzodioxole, chlorophenylmethane and ethylbenzene. According to the air-stable argyrodite type sulfide electrolyte provided by the invention, the stability of the sulfide electrolyte to water can be enhanced, and the ionic conductivity of the sulfide electrolyte can be ensured.

The invention discloses a layered liquid crystal electrolyte based on a dynamic self-assembly strategy and a preparation method and application thereof, and belongs to the technical field of new energy materials, and the preparation method comprises the following steps: uniformly mixing dodecyl non-glycol ether and n-decanol according to a mass ratio, heating and centrifuging to a homogeneous phase to obtain a mixed element; dropwise adding a zinc chloride aqueous solution into the mixed element, carrying out vortex mixing, and centrifuging to remove bubbles; placing the sample in a constant-temperature environment for standing, and screening a phase region with anisotropic characteristics through a polarizing microscope; and continuously carrying out constant-temperature self-assembly on the screened sample, and representing the lamellar liquid crystal structure through a polarized optical microscope and small-angle X-ray scattering. A two-dimensional layered liquid crystal structure is constructed through synergistic self-assembly of the surfactant and the solvent, a zinc ion source is provided in combination with the zinc chloride aqueous solution, and the ion transmission efficiency and the thermal stability are remarkably improved.

The invention provides a low-surface-energy macromolecular photoinitiator, a UV (ultraviolet) LED (light-emitting diode) photocureable coating and a photocureable skin-touch coating. The low-surface-energy macromolecular photoinitiator comprises an ultraviolet light initiator chain segment, a coinitiator amine molecular chain segment, a low-surface-energy chain segment and a functional end group which are arranged repeatedly, and the ultraviolet light initiator chain segment, the coinitiator amine molecular chain segment, the low-surface-energy chain segment and the functional end group are randomly connected through single bonds. The low surface energy chain segment comprises one or more of C1-C30 divalent alkyl and divalent siloxy which are partially substituted or completely substituted by fluorine atoms; the amine molecular chain segment of the co-initiator can be used as a hydrogen donor of an ultraviolet light initiator chain segment, so that the photo-initiation efficiency can be improved; due to the introduction of the low-surface-energy chain segment, the low-surface-energy macromolecular photoinitiator has a certain migration ability, self-assembly can occur on the surface of a coating after film coating, the oxygen isolation ability is improved, and a skin feeling layer is formed through illumination; the functional end group participates in thermocuring, so that the mechanical property of the coating is improved.

The invention discloses a preparation method and application of an amino-functionalized graphene quantum dot modified MXene loose nanofiltration membrane. The preparation method comprises the following steps: mixing an MXene nanosheet dispersion liquid with an aminated graphene quantum dot aqueous solution, and preparing an amino functionalized graphene quantum dot / MXene mixed dispersion liquid by adopting a self-assembly method; and filtering and depositing the obtained mixed dispersion liquid on the modified base membrane to obtain the MXene loose nanofiltration membrane. According to the preparation method disclosed by the invention, the zero-dimensional aminated graphene quantum dots are creatively embedded into the MXene nanosheets, so that the MXene loose nanofiltration membrane which is stable in structure and regular in stacking is prepared. The nanofiltration membrane has good separation performance on different dyes and inorganic salts while effectively inhibiting water swelling, is a next-generation separation membrane with high stability and high selectivity, is mild and simple in preparation process, and has a wide application prospect.

The invention relates to the technical field of biological medicine, in particular to a polypeptide self-assembly PROTAC degradation agent and a preparation method and application thereof. The polypeptide self-assembly PROTAC degradation agent comprises a self-assembly group, an E3 ligase recognition group, a cathepsin response group, an FOXM1 targeting binding group, a connecting peptide and an integrin alpha 6 targeting peptide, the amino acid sequence of the FOXM1 targeted binding group is as shown in SEQ ID NO: 1. According to the polypeptide-based nano delivery system, the drug delivery efficiency is remarkably improved, meanwhile, the risk of side effects is reduced to the minimum through controllable release of active fragments, and a basis is provided for preparation of tumor drugs.

The invention provides a bifunctional nano-enzyme SERS (Surface Enhanced Raman Scattering) detection platform for ultrasensitively detecting mi RNA (Ribonucleic Acid) related to cerebral infarction and a preparation method, and relates to the technical field of biomedical engineering. The preparation method comprises the following steps: synthesizing gold nanorods (AuNRs) by using a seed growth method, and growing Pt on the surface of a product to prepare gold platinum nanorods (Au (at) Pt NRs); the preparation method comprises the following steps: synthesizing gold nano hexagonal plates (AuNHs) by using a seed growth method, and preparing an AuNHs array through oil-water interface self-assembly; and modifying an aptamer complementary chain (H1) on the Au (at) Pt NRs obtained in the step (1) through an Au-S bond. And combining the assembled AuNHs array with a nucleic acid aptamer (cDNA) corresponding to mi R-106a-5p to functionalize the assembled AuNHs array in the step (2), so as to construct an SERS (Surface Enhanced Raman Scattering) detection platform. The target mi R-106a-5p can be specifically combined with cDNA, so that Au (at) Pt NRs carrying H1 are separated from the surface of an AuNHs array, TMB oxidation is reduced, and SERS signals are remarkably reduced. And according to SERS signal intensity, substituting the SERS signal intensity into a linear regression equation to realize quantitative detection of mi RNA.

A photovoltaic structure includes a transparent substrate and a transparent bottom electrode provided over the substrate. The transparent bottom electrode includes a first set of metal lines in contact with a first conducting layer. The first set of metal lines is characterized by an average height (H) of at least about 150 nm, an average width (W), and an aspect ratio H / W of at least about 1 / 250. A self-assembled molecular charge selective layer (SAM-CSL) is disposed over the transparent bottom electrode. A perovskite absorber layer overlays the SAM-CSL, an upper carrier transport layer overlays the perovskite absorber layer, and a top electrode overlays the upper carrier transport layer.