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9858results about "Microballoon preparation" patented technology

Methods for producing droplets for use in capsule-based electrophoretic displays

Methods are provided for forming a dispersion of substantially uniform droplets. An internal phase that includes a plurality of particles suspended in a first fluid is provided and an external phase including a second fluid is provided. The internal phase is vibrated and the internal phase is applied to the external phase. Either the internal phase or a combination of the internal and external phases form a series of droplets or complex droplets of substantially uniform size.
Owner:E INK CORPORATION

Processes for the production of electrophoretic displays

A coating of an encapsulated electrophoretic medium is formed on a substrate (106) by dispersing in a fluid (104) a plurality of electrophoretic capsules (102), contacting at least a portion of a substrate (106) with the fluid (104); and applying a potential difference between at least a part of the portion of the substrate (106) contacting the fluid (104) and a counter-electrode (110) in electrical contact with the fluid (104), thereby causing capsules (102) to be deposited upon at least part of the portion of the substrate (106) contacting the fluid (102). Patterned coatings of capsules containing different colors may be deposited in registration with electrodes using multiple capsule deposition steps. Alternatively, a patterned coating may be deposited upon a substrate containing a conductive layer by varying the conductivity of the conductive layer by radiation exposure or by coating portions of the conductive layer with an insulating layer, typically a photoresist.
Owner:E INK CORPORATION

Potentiation of immune responses with liposomal adjuvants

A high integrity liposome comprising at least one stabile lipid and at least one peptide-like therapeutic agent associated with said liposome, adapted for parenteral administration to an animal, including a human, and method according to manufacture and use. Immunizing dosage forms comprising a liposome and an immunogen, wherein said liposome and immunogen are present in an immunization dose. Additionally, a dosage form, including such form particularly adapted to producing an immune response, comprising a salt according to an organic acid derivative of a sterol and an immunogen wherein said organic acid derivative of a sterol and immunogen are present in an immunization dose, and method according to use is disclosed. Further, a dosage form, including such form particularly adapted to producing an immune response, comprising dimyristoylphosphatidylcholine (DMPC) / cholesterol liposomes, optionally in an aluminum hydroxide gel, and an immunogen wherein said DMPC / cholesterol and immunogen are present in an immunization dose, and method according to use.
Owner:TRANSAVE

Perfume encapsulates

A perfume encapsulate comprises an aminoplast capsule, the capsule shell comprising urea-formaldehyde or melamine-formaldehyde polymer and a second polymer comprising a polymer or copolymer of one or more anhydrides, preferably ethylene / maleic anhydride copolymer. The second polymer improves the stability of the capsules with respect to surfactant, thus improving perfume retention properties and enabling use of the capsules in aqueous surfactant-containing products in a way that has not hitherto been possible.
Owner:QUEST INTERNATIONAL

Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations

The present invention relates to pharmaceutical compositions for delivery of drugs intended to reside in the nose, compositions for nasal administration of drugs, e.g., antiviral agents, and particularly antiviral agents comprising the human major rhinovirus receptor, also known as intercellular adhesion molecule-1 (ICAM-1); to methods of making said nasal drug compositions, and to an improved process for the removal of residual solvent from pharmaceutical matrices.
Owner:BAYER PHARMA CORP

Light-emitting nanoparticles and method of making same

A method for the production of a robust, chemically stable, crystalline, passivated nanoparticle and composition containing the same, that emit light with high efficiencies and size-tunable and excitation energy tunable color. The methods include the thermal degradation of a precursor molecule in the presence of a capping agent at high temperature and elevated pressure. A particular composition prepared by the methods is a passivated silicon nanoparticle composition displaying discrete optical transitions.
Owner:MERCK PATENT GMBH +1

Liposomal apparatus and manufacturing methods

The present invention provides apparatus and processes for producing liposomes. By providing a buffer solution in a first reservoir, and a lipid solution in a second reservoir, continuously diluting the lipid solution with the buffer solution in a mixing chamber produces a liposome. The lipid solution preferably comprises an organic solvent, such as a lower alkanol.
Owner:ARBUTUS BIOPHARMA CORPORAT ION

Method Of Manufacture And The Use Of A Functional Proppant For Determination Of Subterranean Fracture Geometries

Proppants having added functional properties are provided, as are methods that use the proppants to track and trace the characteristics of a fracture in a geologic formation. Information obtained by the methods can be used to design a fracturing job, to increase conductivity in the fracture, and to enhance oil and gas recovery from the geologic formation. The functionalized proppants can be detected by a variety of methods utilizing, for example, an airborne magnetometer survey, ground penetrating radar, a high resolution accelerometer, a geophone, nuclear magnetic resonance, ultra-sound, impedance measurements, piezoelectric activity, radioactivity, and the like. Methods of mapping a subterranean formation are also provided and use the functionalized proppants to detect characteristics of the formation.
Owner:HALLIBURTON ENERGY SERVICES INC

Capsules, materials for use therein and electrophoretic media and displays containing such capsules

An encapsulation material, intended for use in encapsulated electrophoretic displays, comprises the coacervation product of a polyanionic polymer having a vinyl main chain and a plurality of anionic groups bonded to the main chain, with a cationic or zwitterionic water-soluble polymer capable of forming an immiscible second phase on contact with the polyanionic polymer.
Owner:E INK CORPORATION

Creation of libraries of droplets and related species

The present invention is generally related to systems and methods for producing a plurality of droplets. The droplets may contain varying species, e.g., for use as a library. In some cases, the fluidic droplets may be rigidified to form rigidified droplets (e.g., gel droplets). In certain embodiments, the droplets may undergo a phase change (e.g., from rigidified droplets to fluidized droplets), as discussed more herein. In some cases, a species may be added internally to a droplet by exposing the droplet to a fluid comprising a plurality of species.
Owner:PRESIDENT & FELLOWS OF HARVARD COLLEGE

Compositions comprising encapsulated material

A composition such as a water-based consumer product comprises material (e.g. perfume) encapsulated within shell capsules, each capsule comprising an encapsulating wall having an inner surface and an outer surface, with a coating on the inner surface and / or outer surface of the shell wall, the composition further comprising surfactant and / or solvent. The coating can improve the barrier properties of the shell and can enhance retention of the encapsulated materials within the shell.
Owner:QUEST INTERNATIONAL

Electrocatalyst powders, methods for producing powders and devices fabricated from same

Electrocatalyst powders and methods for producing electrocatalyst powders, such as carbon composite electrocatalyst powders. The powders have a well-controlled microstructure and morphology. The method includes forming the particles from an aerosol of precursors by heating the aerosol to a relatively low temperature, such as not greater than about 400° C.
Owner:CABOT CORP

Antigen delivery system and method of production

The present invention concerns polymer particle vaccine delivery systems in which a water insoluble protein antigen, e.g. a lipidated HpaA protein, is incorporated with particles comprising a polymer matrix. The present invention also concerns a method for incorporating such a water insoluble protein antigen with a polymer matrix in order to produce a polymer particle vaccine delivery system. In addition, the invention also provides a vaccine composition comprising the polymer particle delivery system. The vaccine can be used to treat and / or reduce the risk of for example Helicobacter infection.
Owner:ASTRAZENECA AB

Preparation of capsules

Prior art processes for producing protein-based capsules (for example, capsules for use in electrophoretic media) tend to be wasteful because they produce many capsules outside the desired size range, which is typically about 20 to 50 μm. Capsule size distribution and yields can be improved by either (a) emulsifying a water-immiscible phase in a preformed coacervate of the protein; or (b) using a limited coalescence process with colloidal alumina as the surface-active particulate material.
Owner:E INK CORPORATION

Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer

A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of ethylcellulose and then curing the coated substrate at a temperature and relative humidity elevated to a suitable level above ambient conditions until the coated dosage form attains a stabilized dissolution profile substantially unaffected by exposure to storage conditions of elevated temperature and / or elevated relative humidity.
Owner:PURDUE PHARMA LP

Pharmaceutical aerosol composition

Sterile compositions for administration as aerosols are described. They contain an active agent which is poorly water-soluble, a non-ionic surfactant acomponent and a phospholipid component. The compositions are suitable for oral or nasal inhalation, but also for topical or oromucosal administration. They are particulary useful for the efficient pulmonary administration of poorly soluble corticosteroids and can be aerosolized with common nebulizers.
Owner:PARI PHARMA GMBH

Microfluidic devices for controlled viscous shearing and formation of amphiphilic vesicles

ActiveUS20050032240A1Facilitates programmable control of sizeIncrease shear forceMixing methodsTransportation and packagingViscous shearEngineering
Systems and methods that control the size and composition of emulsified droplets, multi-lamellar and asymmetric vesicles, encapsulation of reagents, membrane proteins, and sorting of vesicles / droplets. More particularly, microfluidic devices for controlled viscous shearing of oil-water emulsions of micro- and nano-scale droplets, the subsequent formation of amphiphilic vesicles such as liposomes, polymer vesicles, micelles, and the like, the post-assembly and post-processing of the droplets including splitting, fusing, sorting and the like, polymer emulsions, and the integration of amphiphilic vesicle production-line on a single microfluidic chip. Preferably, the microfluidic device enables oil-water co-flows with tunable viscous shear forces higher than the immiscible interfacial tension forces that generate favorable conditions for droplet formation.
Owner:RGT UNIV OF CALIFORNIA

Seamless capsule for synthesizing biopolymer and method for producing the same

This invention provides a seamless capsule for synthesizing biopolymer, comprising:(a) an aqueous mixture for synthesizing biopolymer,(b) a seamless capsule layer encapsulating said aqueous mixture, formed from polysaccharide or protein, and,(c) a viscous liquid intermediate layer, present between said aqueous mixture and said seamless capsule layer, which is immiscible with water,wherein said seamless capsule has a diameter of 0.01 to 10.0 mm.This invention can also provide a method for producing the seamless capsule.
Owner:MORISHITA JINTAN CO LTD

Microfluidic Synthesis of Organic Nanoparticles

The present invention provides microfluidic systems and methods for the production of particles (e.g., nanoparticles) for drug delivery. The present invention provides microfluidic devices useful for production of particles by nanoprecipitation. The present invention provides highly homogenous compositions of particles produced by inventive microfluidic devices.
Owner:THE BRIGHAM & WOMEN S HOSPITAL INC +1

Processes for the production of electrophoretic displays

A coating of an encapsulated electrophoretic medium is formed on a substrate (106) by dispersing in a fluid (104) a plurality of electrophoretic capsules (102), contacting at least a portion of a substrate (106) with the fluid (104); and applying a potential difference between at least a part of the portion of the substrate (106) contacting the fluid (104) and a counter-electrode (110) in electrical contact with the fluid (104), thereby causing capsules (102) to be deposited upon at least part of the portion of the substrate (106) contacting the fluid (102). Patterned coatings of capsules containing different colors may be deposited in registration with electrodes using multiple capsule deposition steps. Alternatively, patterned coatings of capsules may be formed by applying a fluid form of an electrophoretic medium to a substrate, and applying a temporally varying voltage between an electrode and the substrate. The process may be repeated to allow for deposition of full color displays.
Owner:E INK CORPORATION
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