1636 results about "Astaxanthin" patented technology

The present invention provides means for increasing the storage stability of astaxanthin in a green algal extract, and a green algal extract containing astaxanthin having high storage stability. The present invention provides a green algal extract comprising astaxanthin at a concentration of 0.5 to 20 wt % expressed in terms of free astaxanthin, and at least one phospholipid at a phospholipid concentration of 0.1 to 15 wt %. This green algal extract has an excellent ability to store stably astaxanthin, and even after storage for one week at 60° C. it is possible to retain approximately 80% or more of the astaxanthin.

A new method for krill meal production has been developed using a two step cooking process. In the first step the proteins and phospholipids are removed from the krill and precipitated as a coagulum. In the second stage the krill without phospholipids are cooked. Following this, residual fat and astaxanthin are removed from the krill using mechanical separation methods. A novel krill meal product with superior nutritional and technical properties is prepared.

The invention belongs to the field of microbial fermentation engineering, and discloses schizochytrium limacinum (Aurantiochytrium sp.SD116). The schizochytrium limacinum is stored in China Microbial Culture Collection Administration Committee General Microbial Center with a number of CGMCC No: 6208), and a method for fermenting and producing DHA (Docosahexaenoic Acid) grease utilizing high density of the schizochytrium limacinum. According to the schizochytrium limacinum and the method disclosed by the invention, a bacterial strain fermenting condition is optimized based on element supply and a fermenting control angle, a carbohydrate supplementation operation is carried out, therefore, high-density fermentation is achieved, dry cell weight finally reaches 70.43g / L, grease content reaches 50.1g / L, DHA occupies more than 35% of total content of fatty acid; moreover, bioactive substances such as beta-carotene, astaxanthin and squalene are contained. The complete set of technology is convenient to operate; higher biomass liveweight and DHA content can be obtained; fermenting cost can be reduced; and the method is suitable for industrial fermenting production.

The present invention relates to compositions and methods for modulating hair growth or regrowth. The compositions of the present invention comprise extracts of one or more of the following: Boswellia serrata, Undaria pinnatifida, green tea (e.g., Camellia sinensis), shiso, Pureraria mirifica, luteolin (e.g. Perilla ocymoides leaf extract), astilbin, vitamin E, amentoflavone, tetrahydropiperine, licochalcone, astaxanthin, red clover, Brassica juncea, unfermented green rooibos, enzyme CoQ10, salvia, ximenynic acid, hops oleoresin, apple, soy, saw palmetto, or ellagic extract, or any derivative thereof. In particular, the compositions and methods of the present invention can be used to stimulate or increase hair growth and / or prevent or slow the loss of hair by having one or more of the following functions: (a) inhibiting synthesis of DHT; (b) inhibiting proteasomal activity; (c) inhibiting IL-1 activity; (d) increasing vascularization; (e) increasing expression of vascular endothelial growth factor; (f) increasing expression of keratinocyte growth factor; (g) inhibiting inflammation; or (h) acting as an antibacterial.

The invention relates to processing crustaceans such as krill to oils comprising phospholipids that are Newtonian fluids and / or and have low viscosity, and in particular to the production of oils containing astaxanthin and phospholipids that show Newtonian fluidity and have a low viscosity.

The method of producing chitin, astaxanthin, protein, calcium powder and biofertilizer with shrimp shell includes the following technological steps: crushing shrimp shell, enzymolysis with composite enzyme, extracting with organic solvent, reaction and separating liquid from solid; separating the liquid into hydrolysis liquid and organic liquid ; vacuum concentrating the organic liquid to obtain coarse astaxanthin; eliminating organic solvent from hydrolysis liquid, vacuum concentrating and spray drying to obtain protein powder; soaking the solid in 3 % concentration hydrochloric acid and rinsing to obtain chitin; introducing CO2 gas to the waste acid solution and filtering to obtain active calcium powder; ultrafiltering the coarse astaxanthin liquid to obtain astaxanthin; adding phytic acid and active oligose into the effluent to obtain nutritious liquid as biofertilizer.

Administering water-soluble or dispersible synthetic analogs or derivatives of astaxanthin, lutein, zeaxanthin, or lycophyll and / or other carotenoids to a subject may reduce some of the adverse effects of inflammation in a body organ or tissue. The analogs or derivatives may be incorporated into pharmaceutical, over-the-counter, or nutraceutical preparations. Administration of the analogs or derivatives described herein may reduce deposition of inflammatory mediators such as C-reactive protein, complement system proteins or the membrane attack complex (MAC) in tissues. Reduced deposition of these molecules in tissues may reduce cell damage and / or lysis in the tissues.

The patent relates to health foods containing natural astaxanthin, which is made into liquid capsule containing natural astaxanthin with natural astaxanthin oil, edible oil and fat and natural antioxidant as raw materials by conventional processing; or which is made into power capsule or tables containing natural astaxanthin with natural astaxanthin, natural antioxidant and other health food as raw materials by conventional processing. In comparison with present technology, the advantage of the invention includes, (1) the health food provided in present patent takes natural astaxanthin as main raw material, has the strongest antioxidant, capable of improving human immunity and anti-aging and ranking first in terms of health foods containing natural antioxidant; (2) the health food is made from pure natural materials and without any compound materials and side-effect; (3) the natural astaxanthin of health food coordinately used with shark cartilage, glucosamine hydrochloride, chitosan, propolis and paclitaxel etc as function material, which is capable of enhancing astaxanthin function; (4) adding antioxidant of natural tea-pigment and tea polyphenols is capable of avoiding oxidation of astaxanthin, thus prolonging shelf life more than one year.

Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and / or rheumatoid arthritis have been found with krill oil and / or marine oil in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.

We describe a composition comprising a source of long chain polyunsaturated fatty acid, for example, docosahexaenoic acid (DHA), and a carotenoid, for example, astaxanthin and other nutrients for prophylactic and / or therapeutic use in the healing of trauma- and stress-induced inflammatory conditions.

The present invention is one kind of nutrient reinforcing agent for artificial fry raising of marine animal, and relates to the recipe and preparation process of micro algae bait nutrient reinforcing agent. The microalgae bait nutrient reinforcing agent consists of several kinds of micro algae containing different nutritious components and has grain size of 5-20 microns. It contains great amount of DHA, ARA and natural astaxanthin, and can raise the immunity and survival rate of raised marine animal. It can meet the requirement of hatched fries of fishes, shrimps and shells in feed. For example, when the microalgae bait nutrient reinforcing agent is used in raising turbot, it can raise the survival rate and lower the albinism rate greatly.

The invention provides plant active peptide firming facial mask essence. The essence is prepared from the following components in percentage by weight: 5-20 percent of glycerinum, 0.02-0.06 percent of sodium hyaluronate, 0.01-0.1 percent of allantoin, 0.1-0.5 percent of xanthan gum, 0.1-5 percent of oligopeptide-1, 0.1-5 percent of oligopeptide-6, 0.1-5 percent of centella asiatica extract, 0.1-5 percent of scutellaria baicalensis extract, 0.1-5 percent of astaxanthin, 0.1-5 percent of gingko leaf extract, 0.1-5 percent of houttuynia cordata extract, 0.1-5 percent of licorice root extract, 0.1-5 percent of rhodiola rosea extract, 0.1-5 percent of watermelon pulp extract, 0.1-2 percent of leuconostoc / radish root ferment filtrate and the balance of purified water. The plant active peptide firming facial mask essence has the effect of firming skin and smoothing skin fine lines in a comprehensive regulating manner.

The invention discloses functional compound feed special for greenhouse cultivation of litopenaeus vannamei. The feed is prepared from import fishmeal, peanut meal, fermented peanut meal, bean pulp, fermented bean pulp, yeast extract, cuttlefish meal, shrimp shell meal, high protein flour, monocalcium phosphate, granulesten, fish oil, a vitaminized mineral mixture premix compound and a functional additive. The functional additive is prepared from vitamins C, bacillus subtilis, seaweed ultrafine smashing micro powder and natural astaxanthin according to proportion. The feed effectively solves the problems of stress, immunity reduction, variety quality losses and the like caused by greenhouse large-scale intensive cultivation of the litopenaeus vannamei and meanwhile has the advantages of being balanced in nutrition, low in cost, green, environmentally-friendly and the like. Main umami substances in muscles of the litopenaeus vannamei fed through the feed are obviously improved, the total amino acid, necessary total essential amino acid and the like are improved in a certain extent, indexes such as the muscle strength, the freshness and the taste are obviously improved, the shrimp body color is close to that of wild shrimps, the immunity of juvenile shrimps and adult shrimps is obviously improved, and the survival rate is high. The feed is suitable for being used in greenhouse high-density large-scale cultivation of the litopenaeus vannamei.

A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and / or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy ketone intermediate from ketoisopherone. The optically active dihydroxy ketone intermediate may be converted into optically active astaxanthin derivatives.

The present invention is directed to carotenoid compositions and methods for inhibiting the growth of pathogenic bacteria or for preventing or treating bacterial infections in subjects by administration of an effective amount of astaxanthin and beta-carotene.

The invention provides a preparation method of a high-stability astaxanthin ester self-microemulsion. The high-stability astaxanthin ester self-microemulsion is prepared by mixing astaxanthin ester, carrier oil, a stabilizing agent, an emulsifying agent, an auxiliary emulsifying agent with a water phase under special process conditions according to a certain proportion, and then, distilling at low pressure to remove a solvent. The astaxanthin ester self-microemulsion prepared by the invention can be self-microemulsified in a water-phase medium to form transparent microemulsion, the particle diameter of which is within 100 nm; the solubility of astaxanthin ester in water is increased; simultaneously, the storage stability of astaxanthin ester is obviously increased; the two problems of being water-fast and low in stability of astaxanthin ester are solved; and thus, astaxanthin ester is possibly applied in water-phase foods, drugs and daily chemical products.

The invention relates to an astaxanthin-containing bacterial cellulose membrane product. The unique astaxanthin-containing bacterial cellulose membrane product is obtained by uniformly dispersing astaxanthin into a fine mesh-shaped structure of bacterial cellulose. The disadvantage that the astaxanthin cannot be stored for a long time under general preservation conditions is overcome; and meanwhile, a good beauty and skin care product with anti-aging and whitening functions is also provided for consumers. The astaxanthin in the bacterial cellulose membrane product has stable properties, the structure of the astaxanthin cannot be damaged, and the astaxanthin can be slowly and durably released to the applied skin when the product is used, and achieve good effects of resisting senility, oxidization and wrinkles, whitening and protecting sunshine. Meanwhile, the membrane product also has good water supplement and moisturizing effects due to high water retention performance of the bacterial cellulose.

The present invention involves a new method using micro-algae for the high-efficiency production of astaxanthin, said method comprising steps including the heterotrophic culture of micro-algae, dilution, light-induced culture, harvesting of algae cells and the extraction of astaxanthin. The method of the present invention takes full advantage of the rapid growth of micro-algae in the heterotrophic culture stage and of the high accumulation of astaxanthin brought about by the light-induced culture of the great quantity of algae cells obtained through said heterotrophic culture to significantly increase the efficiency of production of astaxanthin in micro-algae and thereby achieve low-cost, high-efficiency and large scale production of astaxanthin through micro-algae. The method not only provides an important technical means to address the large-scale industrial production of astaxanthin through micro-algae but also ensures an ample source of raw material for the widespread utilization of astaxanthin.

The invention provides a haematococcus extract preparation, and a preparation method and use thereof. A haematococcus extract soft capsule provided by the invention comprises the contents of haematococcus extract and an oleic phase, wherein the astaxanthin content of the haematococcus extract is 2 to 20 percent (w / w); and the mass-to-volume ratio (g / mL) of astaxanthin in the haematococcus extract and the oleic phase is 1-10:100. The invention also provides the method for preparing the haematococcus extract soft capsules. Experiments show that the haematococcus extract soft capsule provided by the invention has stability remarkably superior to that of the haematococcus extract and conventional products and is of great importance to the application of the astaxanthin to antioxidation, the enhancement of immunity, the suppression of tumorigenesis, the prevention and treatment of cardiovascular disease, the prevention of skin aging and the maintenance of health of eyes and the central nervous system.

The invention relates to the technical field of aquaculture feedstuff. Premix material consists of composite vitamin and composite microelement according to the mass ratio of 5 to 10:15 to 20, wherein the composite vitamin consists of vitamin A, vitamin D, vitamin E, vitamin K3, vitamin B1, vitamin B2, vitamin B6, vitamin B12, nicotinic acid, calcium pantothenate, folic acid, biotin, inositol, vitamin C, beta-glucan, garlicin, DMPT, astaxanthin, topaz, antioxidant, mildew inhibitor and wheat middlings; and the composite microelement consists of ferric citrate, zinc sulfate, magnesium sulfate, methionine, potassium iodate, manganese sulfate, copper sulfate, sodium selenite, potassium chloride, choline chloride, betaine and zeolite. The invention has stable raw material sources and complete nutrition. A cultivated object grows rapidly with a high feedstuff conversion rate and good cultivating benefits. Compared with crabs eating other feedstuff sources such as rough fish, corn, bean pulp, and the like, the quality of Chinese mitten crab is improved. The invention relates to the feedstuff additive premix material for the Chinese mitten crab.

The invention discloses aquarium fish feed. The aquarium fish feed is prepared from the following components in parts by weight: 25-45 parts of fish meal, 10-30 parts of flour, 10-45 parts of bean pulp, 5-25 parts of rapeseed meal, 1-3 parts of fish oil, 0.1-10 parts of spirulina, 0.1-3 parts of monocalcium phosphate, 1-3 parts of a fish adhesive, 0.1-5 parts of beer yeast, 0.2-1 part of multi-vitamin, 0.2-1 part of mineral substances and 0.01-1 part of astaxanthin. The aquarium fish feed has the effects of prompting the growth and the development of fishes, improving the immunity of fishes and achieving the purposes of long-term burnishing and long-term color retaining; the aquarium fish feed is convenient to use and can be preserved for a long time and transported in a long distance after being dried and packaged; and the aquarium fish feed is an aquarium fish feed which is free of residue and pollution and is safe, reliable, green and environment-friendly.

The present invention discloses a special penaeus orientalis functional biological feed in the thickness marking period and the functional biological feed consists of the following components: import fish meal, shrimp meal, fermented peanut meal, fermented soybean meal, yeast lysates, cuttlefish powder, high gluten flour, calcium dihydrogen phosphate, soybean lecithin, fish oil, vitamin-mineral premixes, probiotics and functional additives; wherein the probiotics consist of Bacillus subtilis subsp., Candida utilis yeast and Bifidobacterium longum; the functional additives are made of natural astaxanthin, linolenic acid, fermented chlorella and fermented spirulina. The functional biological feed aims at the physical characteristics of high density, high nutrition and fast growth of penaeus orientalis seedlings in the thickness marking period, uses high-quality animal protein, contains high levels of unsaturated fatty acids and bio-fermentation raw materials, is rich in lecithin, has a reasonable balance ratio of calcium and phosphorus, and fortified vitamin nutrition, adds immunoenhancers, living beneficial bacteria and digestive enzymes, promotes the rapid growth, enhances disease resistance and improves survival rate of penaeus orientalis seedlings which have strong body constitution and tidy specifications, and lay a solid foundation for subsequent successful breeding.

The invention relates to a preparation method of a highly-stable and cold water-soluble natural astaxanthin microcapsule preparation. The method concretely comprises the following steps: uniformly mixing astaxanthin oil, an oil-soluble antioxidant and a water-soluble emulsifier under a heating condition to prepare an oil phase; adding a wall material, a water-soluble antioxidant and a filler to purified water, stirring and dissolving above added materials, and adjusting the pH value of the obtained solution to prepare a water phase; and adding the oil phase to the water phase, uniformly stirring the water phase and the oil phase, grinding the obtained mixture through a sand mill, and carrying out one-step granulation on the obtained emulsion through a cold spraying-starch fluidized bed drying technology to obtain the microcapsule preparation with the particle size of 40-100 meshes. The content reservation rate of the microcapsule preparation disposed at 40DEG C under RH of 75% for 6 months is greater than 95%, and 0.1g of the microcapsule preparation is dissolved in 100ml of water to form a clear, transparent and floating oil-free solution, so the microcapsule preparation can be applied in beverages and other aqueous foods.

The invention discloses a method for extracting astaxanthin, which is finished by taking a rhodotorula or microalgae feed liquid containing the astaxanthin as a raw material, and performing separation, drying, crushing wall-breaking processes to the feed liquid. The method comprises the following concrete steps: the raw material is separated first to produce a mashed material with the water content less than or equal to 90 percent; the mashed material is dried to produce feed powder with the water content of between 5 and 10 percent; then an airflow crushing method is adopted to crush the feed powder to particles with diameters less than or equal to 10mu m. In the method, the drying is performed first and then the wall-breaking is performed, so the loss of the astaxanthin is reduced; the airflow crushing method is adopted, and has high wall-breaking rate and short wall-breaking time (only 1 minute or so), the temperature is between 20 and 30 DEG C during the wall-breaking process, and avoids the loss of the astaxanthin due to high-temperature oxidation; and the loss rate of the astaxanthin is less than or equal to 10 percent, and the wall-breaking rate is more than or equal to 90 percent.

The invention discloses a compound feed for enhancing color of rainbow trout. The compound feed is prepared from the following raw materials in parts by weight: 0.1-0.3 part of microelements, 0.03-0.06 part of vitamins, 1-2 parts of minerals, 15-25 parts of imported fish powder, 5-10 parts of shrimp shell powder, 2-5 parts of sleeve-fish ointment, 20-40 parts of bean pulp, 10-20 parts of mixed meal, 5-8 parts of corn protein powder, 2-3 parts of alfalfa powder, 0.04-0.08 part of cholate substances, 1-2 parts of spirulina powder, 4-6 parts of kelp powder, 4-6 parts of grease, 0.02-0.04 part of astaxanthin, 0.2-0.4 part of 0.2% lutein and 15-25 parts of flour. The raw materials such as the imported fish powder and the good-quality bean pulp are selected for meeting nutritional indexes of the rainbow trout, and the carotenoid-rich raw materials such as the spirulina powder, the astaxanthin, the lutein and the corn protein powder are emphatically added for enhancing the color of the rainbow trout according to physiological characteristics of the rainbow trout; the compound feed is convenient to use and free from toxic effects, and contains 40%-45% of crude proteins and 12%-16% of crude fat.

The invention relates to a high-calcium compound shrimp cake and a producing method thereof. The high-calcium compound shrimp cake is prepared through carrying out low-temperature chopping and uniform stirring on an all-acete chinensis paste which is prepared through a high-precision waterproof pulverization technology and proportional minced fillet, chicken breast fillet, salt, vital gluten, diced fatty meat, potato starch, monosodium glutamate, disodium 5'-ribonucleotide, sugar, a water retention agent and a quality improver so as to obtain a cake core material, preparing the cake core material into a circular or elliptic shape through a forming machine, wrapping a layer of bread powder on the outside surface of the cake core, and after the shape of the obtained shrimp cake is finalized by quick-freezing, deep-frying the shrimp cake until the appearance of the shrimp cake is golden, so that the shrimp cake is obtained. The shrimp cake prepared by the producing method is golden in appearance, and fresh, tender and slightly crisp in taste, both has the delicate flavors of shrimps, and preserves various beneficial elements such as rich Ca, P, chitin and astaxanthin in shrimp shells, so that the shrimp cake accords with the demands of people on food nutrition, health, taste, and the like.

The invention discloses a method of extracting Euphausia superba oil by using supercritical carbon dioxide. The method is as follows: freeze drying or heat drying is carried out on Euphausia superba, anhydrous ethanol is sprinkled after Euphausia superba is crushed and ground, uniform stirring is carried out, and supercritical carbon dioxide extraction is carried out after Euphausia superba is immersed for 1 to 2 h; flow for supercritical carbon dioxide extraction comprises the steps of standing and infiltrating Euphausia superba, carrying out static extraction for 20 to 40 m, heating an obtained extract to a temperature of 40 to 50 DEG C and carrying out dynamic extraction for 1 to 2 h. Yield of the Euphausia superba oil is 12 to 18%, and the obtained Euphausia superba oil mainly comprises, by weight, 37 to 43% of phosphatide, 13 to 18% of EPA (eicosapntemacnioc acid), 8 to 12% of DHA (docosahexaenoic acid) and 0.12 to 0.13% of astaxanthin. The method has the advantages of simple flow, stable quality, no harmful influence on environment in the process of extraction, safety and utility.

A process for preparing astaxanthin includes such steps as preparing special culture medium, loading it in reactor, inoculating algae including Haematococcacea able to generate astaxanthin and yeast in it, culturing and fermenting. Its advantages are low cost, and high conversion rate of saccharide, biomass and output of astaxanthin.

A composition for modulating cytokines to regulate an inflammatory or immunomodulatory response. The composition can include at least one of rosehips, blueberry, blackberry, elderberry, cranberry, rosemary, clove, feverfew, nettle root, artichoke, reishi mushroom, olive extract, green tea extract, grape seed extract, resveratrol, Aframomum melegueta, boswellia serrata extract, boswellia forte, ipriflavone, tocotrienols, evening primrose oil, INM-176, borage oil, krill oil, at least one type of xanthophyll (e.g., astaxanthin), green coffee extract and ferulic acid. Specifically, a composition of the invention can include: rosehips and at least one of blackberry, blueberry, elderberry, and optionally krill oil; or rosehips, resveratrol and at least one of Aframomum melegueta and astaxanthin. Based on the cytokine modulation and cytokine response inhibition of the composition, it can be used to regulate an immunomodulatory and / or inflammatory response, and subsequently treat diseases and / or abnormal conditions associated with inflammatory response, for example, cardiovascular conditions, arthritis, osteoporosis and Alzheimer's disease.

The invention relates to a feed additive prepared through mixed fermentation of plant feed protein and the processing waste liquid of chitin and a processing method, which pertains to the field of fermentation engineering. The feed additive takes the plant feed protein and the processing waste liquid of chitin as raw materials, is prepared through adding strains and solid fermentation, and is rich in a plurality of functional components such as astaxanthin, small peptide and probiotics. The feed additive and the processing method can improve the utilization ratio of protein, growth effect of animals as well as survival rate and significantly decrease feed cost; simultaneously, the feed additive and the processing method can also greatly reduce the cost of treating the processing waste liquid of chitin, are conducive to the environmental protection, energy conservation and efficiency increase and have significant social and economical benefits.