111 results about "Polyunsaturated fatty acid" patented technology

The invention discloses a preparation method of hippocampus oil, which comprises the following steps: 1) adding dried hippocampus powder into a dichloromethane-methanol mixed solution, uniformly stirring, and extracting for 24 hours; 2) filtering the leach liquor, adding water, fully and uniformly mixing, standing for 12 hours, and collecting a lower layer organic phase; 3, the organic phase is subjected to rotary evaporation drying.The invention further discloses application of the hippocampus oil in preparation of uric acid lowering products.The hippocampus oil is rich in omega-3 polyunsaturated fatty acid (EPA and DHA), the activity of xanthine oxidase is moderately reduced, release of inflammatory factors is inhibited, and the comprehensive effect of inhibiting generation and relieving inflammation is achieved.

The invention provides paeonia suffruticosa-derived phosphatidyldiacylglycerol acyltransferase 1-2 or a coding gene and application thereof, and belongs to the technical field of functional proteins. The invention relates to phosphatidyldiacylglycerol acyltransferase 1-2 from paeonia ostii, which comprises phosphatidyldiacylglycerol acyltransferase 1-2 from paeonia ostii and / or phosphatidyldiacylglycerol acyltransferase 1-2 from paeonia suffruticosa. Experiments show that the Paeonia ostii-sourced phosphatidyldiacylglycerol acyltransferase 1-2 and / or Paeonia fulva-sourced phosphatidyldiacylglycerol acyltransferase 1-2 not only can synthesize linoleic acid and alpha-linolenic acid by using exogenous polyunsaturated fatty acid, but also does not affect accumulation of yeast total lipid. The peony-sourced phosphatidyldiacylglycerol acyltransferase 1-2 provided by the invention provides a new method for biosynthesis of triacylglycerol, and provides a new way for genetic breeding of oil crops.

The invention provides new application of lauric acid, and researches on the inhibiting effect of lauric acid on a cardiac voltage gated sodium channel Nav1.5 and the action mode of lauric acid in electrophysiological conduction prove that natural polysaturated fatty acid lauric acid is a potential Nav1.5 sodium channel inhibitor for the first time. Electrophysiological characterization shows that lauric acid is the most effective monomer in natural polysaturated fatty acid screened for inhibiting Nav1.5, and the IC50 value is 27.40 + / -12.78 mu M.

The invention discloses polyunsaturated fatty acid microcapsule powder as well as a preparation method and application thereof, and belongs to the field of foods. The microcapsule powder comprises the following raw materials: a core material solution prepared from 10-25% of polyunsaturated fatty acid and 0.5-2% of an emulsifier, and a wall material solution prepared from 2-5% of sodium caseinate, 3-6% of reducing sugar, 15-25% of modified starch and 40-60% of distilled water through heating and stirring. Wherein the mass ratio of the polyunsaturated fatty acid to the wall material is (1: 1.2)-(1: 1.5); and mixing the wall material solution and the core material solution, stirring and shearing, homogenizing and emulsifying at high pressure, sterilizing, and spray-drying to obtain the polyunsaturated fatty acid microcapsule powder. According to the present invention, the fishy smell of the polyunsaturated fatty acid can be covered, and effects of high oil loading capacity, high oxidation stability, high absorption rate, simple process and low cost are provided.

The present embodiments provide a plant-based lipid composition comprising high concentrations of long-chain omega-3 fatty acids, typically as fatty acid esters, comprising DPA, DTA, ETA, or ETrA, optionally with OA or ALA. These enriched lipid compositions have improved stability, and offer a sustainable source for these long-chain omega-3 fatty acids. In some embodiments, these enriched lipid compositions show enhanced modulation of inflammatory markers, such as inhibition of inflammatory cytokines, and offer nutritional or therapeutic value..

This invention discloses a microfluidic method for preparing fish oil microspheres based on viscosity control and its application, belonging to the field of functional food preparation technology. The method involves constructing three viscosity systems (3.47–15.19 mPa·s) by compounding concentrated fish oil and castor oil at a specific volume ratio. Using a 3% polyvinyl alcohol aqueous solution as the continuous phase, water-in-oil fish oil microspheres are prepared under constant pressure in a cross-shaped microfluidic chip. By controlling the viscosity of the oil phase, the microsphere particle size can be precisely controlled within the range of 53.89–72.34 μm, with a coefficient of variation ≤5% and regular morphology. The obtained microspheres exhibit excellent particle size stability under pH 5–7 and 0–2% NaCl conditions. The high-viscosity microspheres show significantly lower acid values ​​and thiobarbituric acid reactant values ​​compared to the low-viscosity group under storage conditions of 4–60℃, with an oxidation stability improvement of over 30%. In vitro digestion experiments show that the low-viscosity microspheres reach peak free fatty acid release rate after 120 min, while the high-viscosity group exhibits a sustained-release effect. This invention achieves simultaneous optimization of fish oil microsphere particle size, stability, and digestive behavior, providing a theoretical basis and precise process parameters for the structured design of ω-3 polyunsaturated fatty acid functional foods.

The invention provides a senescent muscle repairing composition and application, and belongs to the technical field of cosmetics. Comprising polyunsaturated fatty acid, carotenoid, peptides, polydeoxyribonucleotide PDRN and at least one algae extract selected from chlorella, spirulina, brown algae and red algae. According to the senescent muscle repairing composition prepared by the invention, through a carefully selected natural active component system, the composition has a synergistic effect from two major directions of promoting synthesis of ECM key components and inhibiting excessive degradation of ECM, and improves the structural quality of ECM, so that the steady state of skin ECM is effectively recovered, and the purposes of improving wrinkles and improving compactness and elasticity are achieved.

The present disclosure provides techniques for assessing FADS1 activity in a patient. Also provided are techniques for determining the appropriateness of treating a patient with a FADS1-modulating (e.g., inhibiting) compound. This determination can be made by analyzing one or more biological indicators of a FADS1-mediated disease or disorder in the subject. The one or more biological indicators can include one or more of the following in the subject: ratios of polyunsaturated fatty acids ("PUFAs"), the relative abundance of one or more cell types, the relative abundance of one or more differentially expressed genes ("DEGs") (or gene signatures of such DEGs, e.g., RNA), and / or the relative abundance of one or more metabolites. Also disclosed are methods of using FADS1 inhibitors in methods for treating metabolic disorders and obesity.

The application belongs to the technical field of microbial fermentation, and particularly relates to a fermentation product of fruit and vegetable wastes and corn stalks and application thereof. The fermentation product is obtained by inoculating Aspergillus oryzae SLY-M-15 fermentation product and Saccharomyces cerevisiae into a first mixture containing crushed and air-dried corn stalks and fruit and vegetable wastes, performing aerobic fermentation, adding a second mixture containing crushed and air-dried corn stalks and fruit and vegetable wastes and corn cob, performing secondary aerobic fermentation, inoculating Lactobacillus casei, Lactobacillus acidophilus and Lactobacillus fermentum, and performing anaerobic fermentation. The obtained fermentation product is applied to animal feed, can improve the average daily weight gain of mutton sheep, reduce the feed conversion ratio, improve the tenderness and cooked meat rate of mutton, and increase the content of n-3 polyunsaturated fatty acids.

The present disclosure provides techniques for accessing FADS1 activity in a patient. Also provided are techniques for determining the appropriateness of treatment of a patient with a FADS1 modulating (e.g., inhibiting) compound. This determination may be made by analyzing one or more biological indicators of FADS1-mediated disease or disorder in the subject. The one or more biological indicators may include one or more of a ratio of polyunsaturated fatty acids (“PUFAs”) in the subject, a relative abundance of one or more cell types, a relative abundance of one or more differentially expressed genes (“DEGs”) (or gene signatures, such as RNA, for such DEGs), and / or a relative abundance of one or more metabolites. Also disclosed are methods of using FADS1 inhibitors in methods of treating metabolic disorders and obesity.

There are provided compositions comprising at least one compound chosen from compound of formula (I), compound of formula (II), compound of formula (III) and compound of formula (IV); and a cannabinoid for use as a COX-2 inhibitor.

The invention discloses high-oleic-acid sunflower seed oil and a preparation method thereof, and belongs to the technical field of deep processing and refining of vegetable fat. According to the method, polyunsaturated fatty acid in triglyceride is preferentially converted into low-boiling-point fatty acid alkyl ester through selective enzymatic alcoholysis / ester exchange reaction, volatility difference is constructed, and directional enrichment of oleic acid components and segmented removal of low-boiling-point impurities are achieved through multi-stage short-path molecular distillation. According to the method, the content of oleic acid in the sunflower seed oil can be increased from 60-75% to 80-90%, the content of linoleic acid can be reduced from 15-30% to 5-12%, meanwhile, free fatty acid, peculiar smell precursors and oxylysate are effectively removed, the oxidation stability of the product is excellent, and the retention rate of nutritional ingredients is high. The linoleate-rich fraction generated in the technical process can be used as a high-added-value byproduct, so that the synergistic value increase of the main and by-products is realized.

The application provides a preparation method of a corrosion-resistant nanometer wave-absorbing agent, paint and application, and the preparation method comprises the following steps: S1, mixing polyunsaturated fatty acid, polyunsaturated fatty amine and trivalent iron raw materials in a stirrer until the mixture is uniform, heating at 100-150 DEG C for 20-60 min to remove moisture; S2, preheating the reaction system at 200-250 DEG C for 20-60 min, heating to 270-300 DEG C for 20-60 min, and naturally cooling to room temperature; S3, discarding the solution after heating reaction, then adding an organic solvent, mechanically stirring for 20-50 min, and then performing solid-liquid separation, and drying to obtain the product. According to the control of the addition proportion of the reaction raw materials, the particle size, micro-morphology and electromagnetic absorption performance of the final wave-absorbing agent can be changed, and the optimization and improvement of the electromagnetic wave absorption capacity can be realized; the ester organic matter wrapped outside in the reaction process can form a capsule protection layer outside the nanoparticles, isolate external corrosion elements, and itself does not have dielectric characteristics, and has good hydrophobicity, so that the corrosion resistance of the magnetic electromagnetic absorbing agent can be effectively improved.

The application provides a preparation method of high-load polyunsaturated fatty acid oil microcapsules. The preparation method of the high-load polyunsaturated fatty acid oil microcapsules comprises the following steps: (1) dissolving a water-soluble protein wall material in water to obtain an aqueous phase; (2) adding polyunsaturated fatty acid oil to the aqueous phase and performing shear emulsification; and (3) adjusting the solid content of the system obtained in the step (2) to 50-55% to obtain an emulsion. The content of the polyunsaturated fatty acid oil in the polyunsaturated fatty acid oil microcapsules is not less than 40 wt%, and the content of fatty acids with a carbon chain length of more than 20 and an unsaturated double bond of more than 4 in the polyunsaturated fatty acid oil is not less than 40%. The high-load polyunsaturated fatty acid oil microcapsule product obtained by the preparation method has low moisture content, is fluffy, has good instant solubility, has good brewing performance, and has good sensory stability during the shelf life.

There is provided a vegetable-based lipid composition comprising high levels of at least three different long-chain polyunsaturated fatty acids (typically as fatty acid esters). The compositions typically contain DHA as the principal long-chain polyunsaturated fatty acid. The composition is obtainable from a single source by conventional processing methods, and has improved stability properties.

The invention discloses a preparation method of a pumpkin seed oil-probiotic composite microcapsule capable of balancing polyunsaturated fatty acids, and relates to the technical field of biological materials. Comprising a composite microcapsule, and the composite microcapsule takes mixed pressed oil and probiotics as a core material and takes a whey protein and Arabic gum mixture as a wall material; the core material is embedded in the wall material; the mixed pressed oil comprises pumpkin seed oil and linseed oil; the preparation method comprises the following steps: S1, preparing balanced polyunsaturated fatty acid mixed pressed oil; s2, preparing a microcapsule wall material; s3, activating and preparing the probiotics; and S4, preparing the microcapsule. The invention provides the preparation method of the composite microcapsule capable of accurately delivering the probiotics to a target position.

A preparation of a high-conversion compound rumen bypass polyunsaturated fatty acid powder and the use thereof. The preparation comprises: adsorbing a polyunsaturated fatty acid oil by means of an adsorbent under vacuum conditions, and compounding a water-soluble antioxidant and an enzyme for promoting digestion and absorption to form a mixed powder; uniformly mixing and granulating the mixed powder by using a colloid or flour, and carrying out one-layer fixed coating by using a polysaccharide; and performing rumen bypass coating of the one-layer coating granule by using a fat powder or of a monoglyceride and a diglyceride by using a coating machine.

The present invention relates to a personal care composition comprising an unsaturated fatty acid selected from mono-unsaturated or poly-unsaturated fatty acids having carbon chain length from 14 to 24; and a terpenoid. Particularly, the present invention relates to said personal care composition that provides improved anti-aging benefit. Additionally, the present invention also relates to said personal care composition that improves the barrier function of the skin.

The invention provides staphylococcus saprophyticus as well as a culture system and application thereof in lipase production, and belongs to the technical field of microorganisms. The lipase producing strain PKS-3 is separated from oil-rich soil by using a plate method and belongs to staphylococcus saprophyticus, a grease degradation performance determination result shows that the lipase producing strain PKS-3 has a relatively good degradation effect on sunflower seed oil and other vegetable oil rich in linoleic acid, the degradation rate is 50% or above, and the lipase producing strain PKS-3 has the potential of degrading polyunsaturated fatty acid grease; the lipase in the strain is obtained through cloning, and a theoretical basis and an effective means can be provided for development and utilization of microbial resources and industrial application of the lipase.

This invention discloses a method for determining the distribution of fatty acids at the sn-2 position in oils rich in long-chain polyunsaturated fatty acids, belonging to the fields of analytical chemistry and food science. The method introduces a quality control oil sample containing a correction fatty acid, which is bound to any acyl position in the triglyceride molecule. A correction factor is calculated from the measured data of the quality control oil sample, and this correction factor is used to correct for enzymatic hydrolysis efficiency and analytical system bias. This invention innovatively introduces a quality control sample to monitor and correct enzymatic hydrolysis efficiency and separation recovery rate, eliminating systematic errors caused by factors such as enzyme activity fluctuations and operational differences, and greatly improving the reproducibility of the method across different times and operators.

The present application relates to the technical field of baked food, and particularly relates to an antioxidant baked composition and application thereof.The present application provides an antioxidant baked composition, which comprises an antioxidant composition and a baked ingredient; the antioxidant composition comprises the following components in parts by weight: 3-5 parts of chlamydomonas reinhardtii powder, 4-6 parts of tea tree flower powder and 3-5 parts of apocynum venetum tea powder.The chlamydomonas reinhardtii in the antioxidant composition of the present application contains algal polysaccharide and carotenoid, and provides high-quality protein and polyunsaturated fatty acid; the tea tree flower contains flavonoids and tea polysaccharide; the apocynum venetum tea contains flavonoid substances; the three raw materials are compounded in the present application, the active ingredients synergistically act, the antioxidant capacity is significantly improved, and the three raw materials synergistically enrich the nutritional composition (protein, dietary fiber and functional ingredients) of the product, realizing the dual values of "antioxidation + nutrition strengthening".

To provide a rubber composition that serves as a raw material for vulcanized rubber for tires, and a pneumatic tire equipped with vulcanized rubber of the rubber composition, which improves the balance between ice braking performance (grip performance) and response performance such as steering response and driving stability (anti-wandering performance) on frozen road surfaces (icy road surfaces). [Solution] A rubber composition containing diene rubber, porous cellulose particles, and vegetable oil, wherein the vegetable oil is a fatty acid ester triglyceride in which a fatty acid containing at least saturated and unsaturated fatty acids is ester-bonded to glycerin, and the ratio of unsaturated fatty acids in the fatty acid is 50% by mass or more. Preferably, the ratio of polyunsaturated fatty acids in the fatty acid is 15% by mass or more.

This invention relates to a specially formulated krill oil soft capsule composition designed to optimize fat energy supply and help reduce and delay lactic acid buildup, suitable for use in the food, nutritional supplement, health product, or sports supplement industries. The composition comprises the following ingredients by weight percentage: taurine (0-20%), sodium bicarbonate (0-20%), β-alanine (0-5%), citrulline malic acid (0-10%), with the balance being krill oil rich in Omega-3 polyunsaturated fatty acids. By rationally combining these ingredients, not only is the role of krill oil in promoting fat as an energy source enhanced, but the generation and clearance of lactic acid during exercise are also effectively managed, thereby supporting more sustained energy output and faster recovery. Furthermore, this invention provides a method for preparing the above composition and its application in improving athletic performance and accelerating recovery. This composition and its preparation method offer a new option for individuals seeking efficient energy management and physical recovery.

The application relates to the technical field of animal nutrition and meat quality regulation, and particularly relates to application of vascular endothelial growth factor B (VEGF-B) in increasing intramuscular fat content of pigs. The content of VEGF-B in pig serum and the expression level of VEGF-B in skeletal muscle tissue are significantly positively correlated with the intramuscular fat content of pigs, so that VEGF-B can be used as a biomarker for predicting the intramuscular fat content of pigs; meanwhile, fish oil rich in n-3 polyunsaturated fatty acids can promote the expression level of VEGF-B by activating G protein-coupled receptor 120 (GPR120), then increase the transvascular endothelial transport of fatty acids in blood vessels to skeletal muscle, and finally increase the intramuscular fat content.

The present invention aims to provide an agent that can increase butyrate-producing bacteria in the intestinal flora in a simple manner. [Solution] We discovered that an omega-3 polyunsaturated fatty acid-containing agent with a low POV (Post-Octometabolic Variability) has the effect of increasing butyrate-producing bacteria in the intestinal flora, and thus completed the present invention.

The present invention is concerned with materials and methods for the production of genetically modified plants, particularly where the plants are for the production of at least one unsaturated or polyunsaturated fatty acid. The Invention is also concerned with identification of genes conveying an unsaturated fatty acid metabolic property to a plant or plant cell, and generally relates to the field of phosphotidylcholine:diacylglycerol cholinephosphotransferase (PDCT).

The application discloses a preparation method of hippocampus oil, which comprises the following steps: 1) adding hippocampus dry powder into dichloromethane-methanol mixed solution and stirring uniformly, and then leaching for 24 hours; 2) after filtering the leaching solution, adding water and mixing fully, and then standing for 12 hours, and then collecting the lower organic phase; and 3) performing rotary evaporation and drying on the organic phase. The application further discloses the use of the hippocampus oil in the preparation of a product for reducing uric acid. The hippocampus oil is rich in omega-3 polyunsaturated fatty acids (EPA and DHA), shows moderate down-regulation on xanthine oxidase activity and inhibition on the release of inflammatory factors, and achieves the comprehensive effect of 'inhibiting generation and relieving inflammation'.

This invention discloses the application of *Pteris vittata* oil in skincare products. The preparation method of the *Pteris vittata* oil involves first extracting the raw material using supercritical CO2 extraction technology to obtain crude *Pteris vittata* oil; then purifying the crude *Pteris vittata* oil through multi-stage molecular distillation, collecting the light fraction to obtain the final *Pteris vittata* oil. This preparation method can efficiently enrich the antioxidant active ingredients such as tocopherols, squalene, and polyunsaturated fatty acids in the *Pteris vittata* oil. The prepared *Pteris vittata* oil exhibits excellent scavenging ability against DPPH free radicals, superoxide anions, and ABTS free radicals, while significantly enhancing SOD activity, reducing MDA levels, and minimizing oxidative stress damage, thereby exerting antioxidant and anti-aging effects. This provides a safe, gentle, and highly effective natural raw material for anti-aging, whitening, and skin barrier repair skincare products, and has promising market application prospects.

The purpose of the present invention is to provide a palatability improver for pet food, said palatability improver being capable of satisfactorily improving the palatability of a pet food to pets. Specifically, the purpose is to provide a palatability improver for pet food, said palatability improver being capable of satisfactorily improving the palatability of a pet food mainly composed of plant-based ingredients to pets.　It is found that a heat-treated product containing a polyunsaturated fatty acid-containing ingredient and a glutathione-containing yeast extract and / or cysteine-containing yeast extract resulted in improved palatability of a pet food to pets.