Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

22 results about "Polyunsaturated fatty acid" patented technology

Polyunsaturated fatty acids (PUFAs) are fatty acids that contain more than one double bond in their backbone. This class includes many important compounds, such as essential fatty acids and those that give drying oils their characteristic property.

A viscosity-controlled microfluidic fish oil microsphere, its preparation method and application

PendingCN122076334ANervous disorderMetabolism disorderIn vitro digestionPolyvinyl alcohol
This invention discloses a microfluidic method for preparing fish oil microspheres based on viscosity control and its application, belonging to the field of functional food preparation technology. The method involves constructing three viscosity systems (3.47–15.19 mPa·s) by compounding concentrated fish oil and castor oil at a specific volume ratio. Using a 3% polyvinyl alcohol aqueous solution as the continuous phase, water-in-oil fish oil microspheres are prepared under constant pressure in a cross-shaped microfluidic chip. By controlling the viscosity of the oil phase, the microsphere particle size can be precisely controlled within the range of 53.89–72.34 μm, with a coefficient of variation ≤5% and regular morphology. The obtained microspheres exhibit excellent particle size stability under pH 5–7 and 0–2% NaCl conditions. The high-viscosity microspheres show significantly lower acid values ​​and thiobarbituric acid reactant values ​​compared to the low-viscosity group under storage conditions of 4–60℃, with an oxidation stability improvement of over 30%. In vitro digestion experiments show that the low-viscosity microspheres reach peak free fatty acid release rate after 120 min, while the high-viscosity group exhibits a sustained-release effect. This invention achieves simultaneous optimization of fish oil microsphere particle size, stability, and digestive behavior, providing a theoretical basis and precise process parameters for the structured design of ω-3 polyunsaturated fatty acid functional foods.
Owner:DONGGUAN UNIV OF TECH

Selection of patients for the treatment of fads1-mediated diseases or disorders using fads-1 inhibitors

PendingUS20260183297A1DiseaseMetabolite
The present disclosure provides techniques for accessing FADS1 activity in a patient. Also provided are techniques for determining the appropriateness of treatment of a patient with a FADS1 modulating (e.g., inhibiting) compound. This determination may be made by analyzing one or more biological indicators of FADS1-mediated disease or disorder in the subject. The one or more biological indicators may include one or more of a ratio of polyunsaturated fatty acids (“PUFAs”) in the subject, a relative abundance of one or more cell types, a relative abundance of one or more differentially expressed genes (“DEGs”) (or gene signatures, such as RNA, for such DEGs), and / or a relative abundance of one or more metabolites. Also disclosed are methods of using FADS1 inhibitors in methods of treating metabolic disorders and obesity.
Owner:AMGEN INC

A method for determining the sn-2 fatty acid distribution in long chain polyunsaturated fatty acid-enriched oils

PendingCN122409883AFatty acid bindingTriglyceride
This invention discloses a method for determining the distribution of fatty acids at the sn-2 position in oils rich in long-chain polyunsaturated fatty acids, belonging to the fields of analytical chemistry and food science. The method introduces a quality control oil sample containing a correction fatty acid, which is bound to any acyl position in the triglyceride molecule. A correction factor is calculated from the measured data of the quality control oil sample, and this correction factor is used to correct for enzymatic hydrolysis efficiency and analytical system bias. This invention innovatively introduces a quality control sample to monitor and correct enzymatic hydrolysis efficiency and separation recovery rate, eliminating systematic errors caused by factors such as enzyme activity fluctuations and operational differences, and greatly improving the reproducibility of the method across different times and operators.
Owner:瞿瀚鹏

An antioxidant baking composition and uses thereof

PendingCN122250488AImprove antioxidant capacityRealize the dual value of "antioxidation + nutritional enhancement"Dough treatmentBaking processesBiotechnologyApocynum venetum
The present application relates to the technical field of baked food, and particularly relates to an antioxidant baked composition and application thereof.The present application provides an antioxidant baked composition, which comprises an antioxidant composition and a baked ingredient; the antioxidant composition comprises the following components in parts by weight: 3-5 parts of chlamydomonas reinhardtii powder, 4-6 parts of tea tree flower powder and 3-5 parts of apocynum venetum tea powder.The chlamydomonas reinhardtii in the antioxidant composition of the present application contains algal polysaccharide and carotenoid, and provides high-quality protein and polyunsaturated fatty acid; the tea tree flower contains flavonoids and tea polysaccharide; the apocynum venetum tea contains flavonoid substances; the three raw materials are compounded in the present application, the active ingredients synergistically act, the antioxidant capacity is significantly improved, and the three raw materials synergistically enrich the nutritional composition (protein, dietary fiber and functional ingredients) of the product, realizing the dual values of "antioxidation + nutrition strengthening".
Owner:GUANGDONG FOOD & DRUG VOCATIONAL COLLEGE

A softgel capsule composition of krill oil with improved fat energy supply

This invention relates to a specially formulated krill oil soft capsule composition designed to optimize fat energy supply and help reduce and delay lactic acid buildup, suitable for use in the food, nutritional supplement, health product, or sports supplement industries. The composition comprises the following ingredients by weight percentage: taurine (0-20%), sodium bicarbonate (0-20%), β-alanine (0-5%), citrulline malic acid (0-10%), with the balance being krill oil rich in Omega-3 polyunsaturated fatty acids. By rationally combining these ingredients, not only is the role of krill oil in promoting fat as an energy source enhanced, but the generation and clearance of lactic acid during exercise are also effectively managed, thereby supporting more sustained energy output and faster recovery. Furthermore, this invention provides a method for preparing the above composition and its application in improving athletic performance and accelerating recovery. This composition and its preparation method offer a new option for individuals seeking efficient energy management and physical recovery.
Owner:FOK (FUJIAN) BIOTECHNOLOGY CO LTD

Agent for increasing butyrate-producing bacteria in the gut microbiota

ActiveJP7885902B1BiotechnologyButyrate-Producing Bacteria
The present invention aims to provide an agent that can increase butyrate-producing bacteria in the intestinal flora in a simple manner. [Solution] We discovered that an omega-3 polyunsaturated fatty acid-containing agent with a low POV (Post-Octometabolic Variability) has the effect of increasing butyrate-producing bacteria in the intestinal flora, and thus completed the present invention.
Owner:FUJI OIL CO LTD

Method for the production of high levels of PUFA in plants

The present invention is concerned with materials and methods for the production of genetically modified plants, particularly where the plants are for the production of at least one unsaturated or polyunsaturated fatty acid. The Invention is also concerned with identification of genes conveying an unsaturated fatty acid metabolic property to a plant or plant cell, and generally relates to the field of phosphotidylcholine:diacylglycerol cholinephosphotransferase (PDCT).
Owner:BASF PLANT SCI GMBH

Use of a mealworm oil in a skin care product

PendingCN122272460Aavoid destructionHigh retention rateDPPHSuperoxide
This invention discloses the application of *Pteris vittata* oil in skincare products. The preparation method of the *Pteris vittata* oil involves first extracting the raw material using supercritical CO2 extraction technology to obtain crude *Pteris vittata* oil; then purifying the crude *Pteris vittata* oil through multi-stage molecular distillation, collecting the light fraction to obtain the final *Pteris vittata* oil. This preparation method can efficiently enrich the antioxidant active ingredients such as tocopherols, squalene, and polyunsaturated fatty acids in the *Pteris vittata* oil. The prepared *Pteris vittata* oil exhibits excellent scavenging ability against DPPH free radicals, superoxide anions, and ABTS free radicals, while significantly enhancing SOD activity, reducing MDA levels, and minimizing oxidative stress damage, thereby exerting antioxidant and anti-aging effects. This provides a safe, gentle, and highly effective natural raw material for anti-aging, whitening, and skin barrier repair skincare products, and has promising market application prospects.
Owner:JINHUA HERUI LIFE HEALTH TECHNOLOGY CO LTD

Method for producing very-long-chain polyunsaturated fatty acid

The present invention provides a method for producing a very-long-chain polyunsaturated fatty acid, the method comprising reacting a compound represented by Formula II: R1-MgX1 with Formula III: X2-(CH2)m-X in a solvent to obtain a compound represented by Formula I: R1-(CH2)m-X.
Owner:NISSUI CORPORATION

Whole mixed daily ration for dairy goats containing fresh oat grass, and method for its preparation and use

PendingCN122271438AInhibition of growth and reproductionlower water activityFiberPreservative
This invention belongs to the field of dairy goat feed technology, specifically relating to a total mixed ration (TMR) for dairy goats containing fresh oat hay, its preparation method, and its application. The invention involves chopping fresh oat hay, sequentially spraying it with a functional oil-based compound emulsion and an organic acid salt compound preservative solution, followed by static adsorption and mixing treatment, and then gradient mixing with dry-based raw materials to obtain the TMR. This invention is the first to achieve the direct use of high-moisture fresh oat hay in TMR without fermentation. It utilizes the cell wall fiber network of fresh oat hay as a natural carrier for functional oils, allowing the oils to penetrate into the fiber pores through static adsorption, forming a stable physical encapsulation structure and effectively reducing the rumen hydrogenation rate of polyunsaturated fatty acids. The invention employs a low-starch, high-slow-release fiber gradient energy supply design, combined with the organic acid salt compound preservative solution, to achieve synergistic effects in feed preservation, oil protection, and rumen health regulation.
Owner:INNER MONGOLIA SHENGJIAN BIOTECHNOLOGY CO LTD +2

Synthetic polyunsaturated fatty acid conjugated phospholipid yeast engineering bacteria, construction method and application thereof

ActiveCN121699770BIDH1Pyruvate synthesis
The present application relates to a kind of synthetic polyunsaturated fatty acid binding phospholipid yeast engineering bacteria and construction method and application, belong to microbial engineering technical field, the engineering bacteria is with Yarrowia lipolytica as bottom cell, knock out the Mhy1, Iro1, IDH1, CEX1 gene in its genome for generating mycelium, synthesis of triglyceride, citric acid metabolism, citric acid efflux;Phospholipid synthesis, pyruvate synthesis, polyunsaturated fatty acid synthesis and acyltransferase CDS1, OPI3, Mce2, LplA, △9Elo, △8Des, △5Des, △17Des, △5Elo, △15Des, LPCAT3 gene are sequentially connected together, as an expression module is integrated in the URA site of genome.The yeast engineering bacteria of the present application obtains polyunsaturated fatty acid binding phospholipid in one step efficiently, and phospholipid yield is 151.19 mg / g, and in binding fatty acid, EPA content is 13.2%.
Owner:YELLOW SEA FISHERIES RES INST CHINESE ACAD OF FISHERIES SCI

Application of metal organic framework material, method for improving yield of polyunsaturated fatty acid of oleaginous microorganism and preparation method of microbial oil

PendingCN122071726AImmobilised enzymesFungiBiotechnologyMicrobial oil
The invention relates to the field of fermentation, and discloses application of a metal organic framework material, a method for improving the yield of polyunsaturated fatty acid of an oil-producing microorganism and a preparation method of microbial oil. The method for improving the yield of the polyunsaturated fatty acid of the oleaginous microorganism comprises the following steps: inoculating the oleaginous microorganism into a culture medium containing a metal organic framework material for culturing; the metal organic framework material is selected from at least one of a cerium-based metal organic framework material, a copper-zinc-based metal organic framework material and a copper-based metal organic material. The method provided by the invention can improve the yield of the polyunsaturated fatty acid in the oleaginous microorganisms, and has a remarkable market prospect.
Owner:NANJING NORMAL UNIVERSITY

Bacopa monnieri extract containing omega-3 polyunsaturated fatty acid composition that enhances hippocampal activity and improve memory

ActiveNL2040949B1Brain developmentPhospholipid
Disclosed is an ActiOmega® composition (unsaturated fatty acids and phospholipids) comprising Bacopa monnieri extracts. The composition in the present invention can improve concentration, enhance cognition, improve learning and memory abilities, increase the release and transmission rate of neurotransmitters, enhance hippocampal activity, promote the absorption and utilization of DHA in the human body and the brain development. The DHA in the present invention achieves efficient purification and impurity removal through ultra-high vacuum molecular distillation technology (without the need for solvents), and ensures almost no fishy odourthrough the high vacuum steam deodorization process, with higher DHA content and purity, natural green colour, easy access to the brain, and high bioavailability.
Owner:MOMS GARDEN GMBH

Plasticizer for rubber, rubber composition, and molded article

PCT designated stageWO2026133782A1Polymer sciencePlasticizer
The present invention provides a plasticizer for rubber capable of exhibiting sufficient plasticizing effect on rubber while improving compatibility with rubber. Specifically, the plasticizer for rubber comprises a diester obtained from a polyoxyalkylene glycol and a monocarboxylic acid as reaction raw materials, wherein the monocarboxylic acid is a fatty acid having 12 to 24 carbon atoms and includes a polyunsaturated fatty acid having 12 to 24 carbon atoms.
Owner:DIC CORP

A fattening pig feed formula containing peony seed oil and application thereof

PendingCN122375690AFodderPolyunsaturated fatty acid
The present application belongs to the technical field of animal feed processing, and particularly relates to a fattening pig feed formula containing peony seed oil and application thereof. The feed formula is composed of a basic daily ration raw material without added fat, soybean oil and peony seed oil; the soybean oil and the peony seed oil serve as the only fat source of the feed formula; the mass content of alpha-linolenic acid in the peony seed oil is greater than or equal to 38%; and the mass ratio of n-6 polyunsaturated fatty acid to n-3 polyunsaturated fatty acid in the feed formula is 1.0-5.0:1. The present application realizes the technical breakthrough of muscle gain without fat gain on fattening pigs for the first time by designing the feed formula containing peony seed oil and precisely regulating the n-6 / n-3 PUFA ratio of the feed.
Owner:INSTITUTE OF SUBTROPICAL AGRICULTURE CHINESE ACADEMY OF SCIENCES

Cosmetic or dermatological composition and uses thereof

PCT designated stageWO2026150174A1Vitamin CVegetable oil
The present invention relates to a cosmetic or dermatological composition and to the use thereof, in particular for enhancing and firming the skin, and combating a dull complexion. The cosmetic or dermatological composition comprises, in % by weight relative to the total weight of the composition, from 3 to 4% by weight of at least one vegetable oil rich in essential polyunsaturated fatty acids; a combination of 0.002 to 0.02% of a copper salt, 0.02 to 0.2% of a zinc salt, and 0.02 to 0.2% of a magnesium salt; a myrtle essential oil; and vitamin C and / or a derivative thereof. The present invention also relates to a cosmetic treatment method comprising a step of applying an effective quantity of the composition to a person's skin.
Owner:LAB M&L SA

A method of identifying grass-fed beef

PendingCN122361676AGrazingAgricultural science
The application discloses a method for identifying grazing beef, and relates to the technical field of livestock product quality identification, and comprises the following steps: detecting three core indexes of a beef sample, i.e., a yellowness value, an n-6 / n-3 polyunsaturated fatty acid ratio and a shear force, and quickly and accurately determining whether the beef is raised by grazing or feeding in a shed. The application is based on the key quality differences between grazing beef and feeding beef, and establishes a scientific identification method and threshold standard. The method is simple to operate and has high accuracy, can be used for grassland beef quality certification and brand protection, and has important economic value and market application prospect.
Owner:INSTITUTE OF ANIMAL SCIENCES OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES

An anti-aging plant composition and a method for preparing the same

The present application provides an anti-aging plant composition and a preparation method thereof, and belongs to the field of medical, dental or cosmetic formulations. The composition is compounded by Pseudomonas stutzeri fermented Coptis extract, Bacillus subtilis fermented Dendrobium officinale extract, Galangal extract and plant oil rich in polyunsaturated fatty acids. The lipopeptide biosurfactant produced in situ by directional fermentation of double bacteria is combined with high shear homogenization process to realize sub-micron self-emulsification of oil without adding chemical surfactants. The present application significantly improves the transdermal penetration of active components and the synergistic anti-aging effect, and has a refreshing skin feel and high safety, and is suitable for various anti-aging cosmetics.
Owner:YIYANG TONGKANG (GUANGZHOU) PHARMACEUTICAL CO LTD +1

DHA enriched polyunsaturated fatty acid compositions

PendingUS20260182598A1LipidomeLipid composition
There is provided a vegetable-based lipid composition comprising high levels of at least three different long-chain polyunsaturated fatty acids (typically as fatty acid esters). The compositions typically contain DHA as the principal long-chain polyunsaturated fatty acid. The composition is obtainable from a single source by conventional processing methods, and has improved stability properties.
Owner:NUSEED NUTRITIONAL US INC

A double Pickering emulsion for targeted delivery of polyunsaturated fatty acids, its preparation method and application

PendingCN122297391ANutritionSoya bean
This invention relates to the field of nutritional intervention technology, and more particularly to a double Pickering emulsion for targeted delivery of polyunsaturated fatty acids, its preparation method, and its application. The invention first prepares folic acid-modified soy protein isolate-chitosan electrostatic composite particles as solid particle emulsifiers to stably deliver polyunsaturated fatty acids in a double Pickering emulsion. The folic acid-modified soy protein isolate-chitosan electrostatic composite particles utilize the amphiphilic nature of soy protein isolate and the steric hindrance effect of chitosan to construct a dense, three-dimensional rigid physical barrier at the oil-water interface, significantly reducing the oxidative degradation rate of polyunsaturated fatty acids, ensuring their storage stability, and achieving long-term stability. Simultaneously, by leveraging the active targeting mediated by folic acid receptors and the pH-responsive properties of chitosan, targeted and precise controlled release and delivery of polyunsaturated fatty acids in the colon are achieved, providing a solid technical foundation for precise nutritional intervention in colon cancer.
Owner:NORTHWEST UNIV

Estrosphere preparation, method of production thereof and use

PCT designated stageWO2026104929A1Organic active ingredientsAntiviralsDiseaseEstradiolum
An estrosphere preparation comprising an ester phase and an aqueous phase characterised in that the ester phase comprises α-linolenic acid ethyl ester, or a mixture of α-linolenic acid ethyl ester with one or more components selected from the group comprising polyunsaturated fatty acids ethyl esters (PUFA ethyl esters) or triglycerides, ethanol, and emulsifier, in a weight ratio of between 2:0.5:1 and 8:2:1, respectively, and the aqueous phase comprises water with glycerol at a final concentration of 2.25% by weight, wherein the weight ratio of α-linolenic acid ethyl ester, or of the mixture of α-linolenic acid ethyl ester with one or more components to ethanol, emulsifier and water is between 2:0.5:1:45 and 8:2:1:45, respectively. A method for producing such an estrosphere preparation. Said preparation for use in the treatment of cancer and viral diseases.
Owner:ONCOTURN SPÓŁKA Z OGRANICZONĄ ODPOWIEDZIALNOŚCIĄ

Single cell protein with enhanced polyunsaturated fatty acid content

PendingBD2024365A0Single-cell proteinCupriavidus necator
The present disclosure relates to single cell protein (SCP) products obtained from Cupriavidus necator that has been engineered to produce a favorable fatty acid profile. The biomass produced by the C. necator and the SCP products that include it contain unsaturated fatty acids that are not naturally produced by C. necator.
Owner:LANZATECH INC