155 results about "Polyunsaturated fatty acid" patented technology

A process produces aliphatic monocarboxylic acids and α,ω-dicarboxylic acids or α,ω-dicarboxylic monoesters by electrochemical oxidation of unsubstituted or at least monosubstituted, monounsaturated or polyunsaturated fatty acids or fatty acid esters in the presence of an inorganic or organic nitrate salt in an electrolysis cell in a reaction medium in the presence of oxygen.

The present invention provides a method for inducing fat accumulation in a cell of a fish, including contacting a cell obtained or derived from a fish with an effective amount of a composition including: (i) a fat accumulation inducing agent; and (ii) a carrier, wherein the fat accumulation inducing agent consists essentially of a free fatty acid and a peroxisome proliferator-activated receptor gamma (PPARy) agonist. Further provided are a cultured fish cell including an increased amount of a PUFA and a reduced amount of MUFA, compared to a control fish cell, and an edible composition including the same.

The invention belongs to the field of food processing, and discloses a preparation method and application of a targeted colon delivery polyunsaturated fatty acid grease microcapsule. 11S globulin in soybeans and Arabic gum are used as wall materials of the microcapsule, complex coacervation of the 11S globulin in the soybeans and the Arabic gum is induced under a certain pH condition, so that oil drops are wetted by a coacervate, a core-shell structure is formed, a coacervate phase is further stabilized through glucan to inhibit coalescence, and on the basis, the microcapsule is prepared. And tannic acid, polysaccharide and protein can form hydrogen bonds and generate hydrophobic interaction to further crosslink the condensed phase to obtain the microcapsule capable of resisting digestion of the stomach and the small intestine, so that colon delivery of polyunsaturated fatty acid is realized.

The invention provides a preparation method of a milk goat total mixed ration containing fresh oat grass, and the method comprises the following steps: preparing a first fermentation product from peanut straw, soybean meal and wheat bran, then carrying out mixed fermentation on the first fermentation product and corn straw to prepare a second fermentation product, and mixing the second fermentation product with other components containing the fresh oat grass to prepare the milk goat total mixed ration. The milk goat total mixed ration provided by the invention can improve the milk yield of milk goats or improve the level of polyunsaturated fatty acids in goat milk.

The present invention provides a method for preparing Maillard polyunsaturated fatty acid oil microcapsules. The method for preparing the polyunsaturated fatty acid oil microcapsules comprises the following steps: (1) dissolving sodium caseinate, glucose and lactose in water and mixing them evenly, adding a moisture retaining agent, adjusting the Maillard reaction pH to 8-10, and obtaining an aqueous phase after the reaction; (2) adding polyunsaturated fatty acid oil to the aqueous phase and emulsifying by shearing; (3) adding cellulose and its derivatives to the system obtained in step (2), and shearing to obtain an emulsion; the content of polyunsaturated fatty acid oil in the polyunsaturated fatty acid oil microcapsules is not less than 40wt%. The preparation method provided by the present invention can improve the rehydration property of the Maillard microcapsule product with high oil content, while ensuring that the product is not over-dried, improving the product sensory properties, and ensuring its sensory stability during the shelf life.

The present invention relates to compounds according to general formula (I) which are metabolically robust analogues of bioactive lipid mediators derived from omega-3 polyunsaturated fatty acids (n-3 PUFAs) for use in treating or reducing the risk of developing or preventing: (i) neovascularization and / or (ii) inflammatory disorder, in particular, ophthalmic disorders associated with neovascularization and / or inflammation.

The invention discloses a preparation method of hippocampus oil, which comprises the following steps: 1) adding dried hippocampus powder into a dichloromethane-methanol mixed solution, uniformly stirring, and extracting for 24 hours; 2) filtering the leach liquor, adding water, fully and uniformly mixing, standing for 12 hours, and collecting a lower layer organic phase; 3, the organic phase is subjected to rotary evaporation drying.The invention further discloses application of the hippocampus oil in preparation of uric acid lowering products.The hippocampus oil is rich in omega-3 polyunsaturated fatty acid (EPA and DHA), the activity of xanthine oxidase is moderately reduced, release of inflammatory factors is inhibited, and the comprehensive effect of inhibiting generation and relieving inflammation is achieved.

The invention provides a functional wet food for improving pet hair health and a preparation method thereof, and belongs to the technical field of pet foods.The functional wet food is prepared from, by weight, 40%-45% of meat, 4%-7% of vegetables, 6%-10% of functional microcapsules, 0.2%-0.5% of mineral additives, 0.3%-0.7% of vitamins, 0.5%-1% of natural humectants and the balance deionized water. The functional microcapsule prepared by coating the polyunsaturated fatty acid and the traditional Chinese medicine extract with the chitosan can enhance the stability of the polyunsaturated fatty acid and the palatability of wet grains, and meanwhile, the polyunsaturated fatty acid and the traditional Chinese medicine extract in the microcapsule can achieve a synergistic effect, so that the skin and hair states of pets are improved from inside to outside.

The present invention provides a kind of composition containing bird's nest acid, phospholipid and polyunsaturated fatty acid and preparation method thereof, composition, when not adding any additives, bird's nest acid is dispersed in DHA grease in functional ingredients, while solving the problem that DHA is easily oxidized, promotes brain development, regulates immunity, promotes the absorption and utilization of minerals in the intestine and the effects of beauty and skin care. Phospholipids can prevent the sedimentation of bird's nest acid in ω 3 polyunsaturated fatty acid grease, and are phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol or phosphatidylserine. Not only can the sedimentation of bird's nest acid be prevented, but also the growth of nerve cells can be supported, thereby improving the absorption rate of DHA in the brain. Especially PS, itself can not only nourish the brain, enhance brain function, but also relieve mental stress and improve cognition, and is called "brain nutrient".

The invention provides paeonia suffruticosa-derived phosphatidyldiacylglycerol acyltransferase 1-2 or a coding gene and application thereof, and belongs to the technical field of functional proteins. The invention relates to phosphatidyldiacylglycerol acyltransferase 1-2 from paeonia ostii, which comprises phosphatidyldiacylglycerol acyltransferase 1-2 from paeonia ostii and / or phosphatidyldiacylglycerol acyltransferase 1-2 from paeonia suffruticosa. Experiments show that the Paeonia ostii-sourced phosphatidyldiacylglycerol acyltransferase 1-2 and / or Paeonia fulva-sourced phosphatidyldiacylglycerol acyltransferase 1-2 not only can synthesize linoleic acid and alpha-linolenic acid by using exogenous polyunsaturated fatty acid, but also does not affect accumulation of yeast total lipid. The peony-sourced phosphatidyldiacylglycerol acyltransferase 1-2 provided by the invention provides a new method for biosynthesis of triacylglycerol, and provides a new way for genetic breeding of oil crops.

The invention provides new application of lauric acid, and researches on the inhibiting effect of lauric acid on a cardiac voltage gated sodium channel Nav1.5 and the action mode of lauric acid in electrophysiological conduction prove that natural polysaturated fatty acid lauric acid is a potential Nav1.5 sodium channel inhibitor for the first time. Electrophysiological characterization shows that lauric acid is the most effective monomer in natural polysaturated fatty acid screened for inhibiting Nav1.5, and the IC50 value is 27.40 + / -12.78 mu M.

The invention discloses polyunsaturated fatty acid microcapsule powder as well as a preparation method and application thereof, and belongs to the field of foods. The microcapsule powder comprises the following raw materials: a core material solution prepared from 10-25% of polyunsaturated fatty acid and 0.5-2% of an emulsifier, and a wall material solution prepared from 2-5% of sodium caseinate, 3-6% of reducing sugar, 15-25% of modified starch and 40-60% of distilled water through heating and stirring. Wherein the mass ratio of the polyunsaturated fatty acid to the wall material is (1: 1.2)-(1: 1.5); and mixing the wall material solution and the core material solution, stirring and shearing, homogenizing and emulsifying at high pressure, sterilizing, and spray-drying to obtain the polyunsaturated fatty acid microcapsule powder. According to the present invention, the fishy smell of the polyunsaturated fatty acid can be covered, and effects of high oil loading capacity, high oxidation stability, high absorption rate, simple process and low cost are provided.

The utility model discloses homogenizing equipment for processing polyunsaturated fatty acid-based antioxidant cream, which relates to the related field of cream processing equipment and comprises a tank body, a base is mounted at the bottom of the tank body through bolts, a feeding pipe is mounted on a perforated pipeline at the top of the tank body, and an auxiliary stirring component is arranged at the left end of the outer side surface of a stirring shaft at the bottom of a stirring motor. The stirring motor drives the stirring plate, the through plate and the guide plate to stir ingredients in the tank body, so that the ingredients collide with one another through the through plate and the through hole to accelerate mixing, and the ingredients in the tank body are upwards or downwards rushed out through the rotating guide plate; the material cleaning assembly is arranged at the left end of the inner side face of the tank body, when a scraping plate makes contact with the inner wall of the tank body, generated counter-acting force drives a sliding rod to compress a spring, in this way, cream adhering to the inner wall or the inner bottom of the tank body can be scraped away through the scraping plate and a material guide disc, and the scraped cream can be concentrated, gathered and discharged through the material guide disc.

The present embodiments provide a plant-based lipid composition comprising high concentrations of long-chain omega-3 fatty acids, typically as fatty acid esters, comprising DPA, DTA, ETA, or ETrA, optionally with OA or ALA. These enriched lipid compositions have improved stability, and offer a sustainable source for these long-chain omega-3 fatty acids. In some embodiments, these enriched lipid compositions show enhanced modulation of inflammatory markers, such as inhibition of inflammatory cytokines, and offer nutritional or therapeutic value..

This invention discloses a microfluidic method for preparing fish oil microspheres based on viscosity control and its application, belonging to the field of functional food preparation technology. The method involves constructing three viscosity systems (3.47–15.19 mPa·s) by compounding concentrated fish oil and castor oil at a specific volume ratio. Using a 3% polyvinyl alcohol aqueous solution as the continuous phase, water-in-oil fish oil microspheres are prepared under constant pressure in a cross-shaped microfluidic chip. By controlling the viscosity of the oil phase, the microsphere particle size can be precisely controlled within the range of 53.89–72.34 μm, with a coefficient of variation ≤5% and regular morphology. The obtained microspheres exhibit excellent particle size stability under pH 5–7 and 0–2% NaCl conditions. The high-viscosity microspheres show significantly lower acid values ​​and thiobarbituric acid reactant values ​​compared to the low-viscosity group under storage conditions of 4–60℃, with an oxidation stability improvement of over 30%. In vitro digestion experiments show that the low-viscosity microspheres reach peak free fatty acid release rate after 120 min, while the high-viscosity group exhibits a sustained-release effect. This invention achieves simultaneous optimization of fish oil microsphere particle size, stability, and digestive behavior, providing a theoretical basis and precise process parameters for the structured design of ω-3 polyunsaturated fatty acid functional foods.

The invention relates to the field of microalgae active component extraction, and discloses a method for extracting fucoxanthine and polyunsaturated fatty acid from microalgae and an extracted product thereof, the method comprises the following steps: S1, carrying out first extraction on the microalgae by using a low-concentration alcohol solution, and carrying out solid-liquid separation to obtain a first algae cake and a first extracting solution; and S2, carrying out second extraction on the first algae cake obtained in the step S1 by using a high-concentration alcohol solution, and carrying out solid-liquid separation to obtain a second algae cake and a second extracting solution. According to the method, the low-concentration alcoholic solution and the high-concentration alcoholic solution are matched for extraction, the method is simple, efficient, low in cost and suitable for large-scale production, the problem of residues of toxic solvents such as n-hexane is avoided, the alcoholic solution can be recycled, the proportion of the low-concentration alcoholic solution and the high-concentration alcoholic solution in a final finished product is close to that in natural microalgae cells, and the method is suitable for large-scale production. And the composition does not need to be compounded again.

The invention provides a senescent muscle repairing composition and application, and belongs to the technical field of cosmetics. Comprising polyunsaturated fatty acid, carotenoid, peptides, polydeoxyribonucleotide PDRN and at least one algae extract selected from chlorella, spirulina, brown algae and red algae. According to the senescent muscle repairing composition prepared by the invention, through a carefully selected natural active component system, the composition has a synergistic effect from two major directions of promoting synthesis of ECM key components and inhibiting excessive degradation of ECM, and improves the structural quality of ECM, so that the steady state of skin ECM is effectively recovered, and the purposes of improving wrinkles and improving compactness and elasticity are achieved.

The present disclosure provides techniques for assessing FADS1 activity in a patient. Also provided are techniques for determining the appropriateness of treating a patient with a FADS1-modulating (e.g., inhibiting) compound. This determination can be made by analyzing one or more biological indicators of a FADS1-mediated disease or disorder in the subject. The one or more biological indicators can include one or more of the following in the subject: ratios of polyunsaturated fatty acids ("PUFAs"), the relative abundance of one or more cell types, the relative abundance of one or more differentially expressed genes ("DEGs") (or gene signatures of such DEGs, e.g., RNA), and / or the relative abundance of one or more metabolites. Also disclosed are methods of using FADS1 inhibitors in methods for treating metabolic disorders and obesity.

The application belongs to the technical field of microbial fermentation, and particularly relates to a fermentation product of fruit and vegetable wastes and corn stalks and application thereof. The fermentation product is obtained by inoculating Aspergillus oryzae SLY-M-15 fermentation product and Saccharomyces cerevisiae into a first mixture containing crushed and air-dried corn stalks and fruit and vegetable wastes, performing aerobic fermentation, adding a second mixture containing crushed and air-dried corn stalks and fruit and vegetable wastes and corn cob, performing secondary aerobic fermentation, inoculating Lactobacillus casei, Lactobacillus acidophilus and Lactobacillus fermentum, and performing anaerobic fermentation. The obtained fermentation product is applied to animal feed, can improve the average daily weight gain of mutton sheep, reduce the feed conversion ratio, improve the tenderness and cooked meat rate of mutton, and increase the content of n-3 polyunsaturated fatty acids.

The present disclosure provides techniques for accessing FADS1 activity in a patient. Also provided are techniques for determining the appropriateness of treatment of a patient with a FADS1 modulating (e.g., inhibiting) compound. This determination may be made by analyzing one or more biological indicators of FADS1-mediated disease or disorder in the subject. The one or more biological indicators may include one or more of a ratio of polyunsaturated fatty acids (“PUFAs”) in the subject, a relative abundance of one or more cell types, a relative abundance of one or more differentially expressed genes (“DEGs”) (or gene signatures, such as RNA, for such DEGs), and / or a relative abundance of one or more metabolites. Also disclosed are methods of using FADS1 inhibitors in methods of treating metabolic disorders and obesity.

Disclosed are cosmetic compositions and skin care products that are stabilized against lipid chain auto-oxidation. In particular, this invention substitutes a portion of polyunsaturated fatty acids used in cosmetic compositions and skin care products with a corresponding deuterated polyunsaturated fatty acid.

There are provided compositions comprising at least one compound chosen from compound of formula (I), compound of formula (II), compound of formula (III) and compound of formula (IV); and a cannabinoid for use as a COX-2 inhibitor.

The invention discloses high-oleic-acid sunflower seed oil and a preparation method thereof, and belongs to the technical field of deep processing and refining of vegetable fat. According to the method, polyunsaturated fatty acid in triglyceride is preferentially converted into low-boiling-point fatty acid alkyl ester through selective enzymatic alcoholysis / ester exchange reaction, volatility difference is constructed, and directional enrichment of oleic acid components and segmented removal of low-boiling-point impurities are achieved through multi-stage short-path molecular distillation. According to the method, the content of oleic acid in the sunflower seed oil can be increased from 60-75% to 80-90%, the content of linoleic acid can be reduced from 15-30% to 5-12%, meanwhile, free fatty acid, peculiar smell precursors and oxylysate are effectively removed, the oxidation stability of the product is excellent, and the retention rate of nutritional ingredients is high. The linoleate-rich fraction generated in the technical process can be used as a high-added-value byproduct, so that the synergistic value increase of the main and by-products is realized.

The present disclosure relates to a specific high melt strength polypropylene comprising units derivable from propylene and at least one polyunsaturated fatty acid or an ester thereof, a polymer composition comprising such a high melt strength polypropylene, a product comprising such a high melt strength polypropylene or the polymer composition comprising the same, a process for preparing such a high melt strength polypropylene as well as its use for film making or extrusion coating.

The application provides a preparation method of a corrosion-resistant nanometer wave-absorbing agent, paint and application, and the preparation method comprises the following steps: S1, mixing polyunsaturated fatty acid, polyunsaturated fatty amine and trivalent iron raw materials in a stirrer until the mixture is uniform, heating at 100-150 DEG C for 20-60 min to remove moisture; S2, preheating the reaction system at 200-250 DEG C for 20-60 min, heating to 270-300 DEG C for 20-60 min, and naturally cooling to room temperature; S3, discarding the solution after heating reaction, then adding an organic solvent, mechanically stirring for 20-50 min, and then performing solid-liquid separation, and drying to obtain the product. According to the control of the addition proportion of the reaction raw materials, the particle size, micro-morphology and electromagnetic absorption performance of the final wave-absorbing agent can be changed, and the optimization and improvement of the electromagnetic wave absorption capacity can be realized; the ester organic matter wrapped outside in the reaction process can form a capsule protection layer outside the nanoparticles, isolate external corrosion elements, and itself does not have dielectric characteristics, and has good hydrophobicity, so that the corrosion resistance of the magnetic electromagnetic absorbing agent can be effectively improved.

The application provides a preparation method of high-load polyunsaturated fatty acid oil microcapsules. The preparation method of the high-load polyunsaturated fatty acid oil microcapsules comprises the following steps: (1) dissolving a water-soluble protein wall material in water to obtain an aqueous phase; (2) adding polyunsaturated fatty acid oil to the aqueous phase and performing shear emulsification; and (3) adjusting the solid content of the system obtained in the step (2) to 50-55% to obtain an emulsion. The content of the polyunsaturated fatty acid oil in the polyunsaturated fatty acid oil microcapsules is not less than 40 wt%, and the content of fatty acids with a carbon chain length of more than 20 and an unsaturated double bond of more than 4 in the polyunsaturated fatty acid oil is not less than 40%. The high-load polyunsaturated fatty acid oil microcapsule product obtained by the preparation method has low moisture content, is fluffy, has good instant solubility, has good brewing performance, and has good sensory stability during the shelf life.

The present disclosure provides techniques for acquiring FADS1 activity in a patient. Also provided are techniques for determining the suitability of treating a patient with a FADS1 regulatory (e.g., inhibitory) compound. The determination may be made by analyzing one or more biological indicators of a FADS1-mediated disease or disorder in the subject. The one or more biological indicators may include one or more of a ratio of polyunsaturated fatty acids ("PUFAs") in the subject, a relative abundance of one or more cell types, a relative abundance of one or more differentially expressed genes ("DEG") (or gene characteristics, e.g., RNA for such DEG), and / or a relative abundance of one or more metabolites. Also disclosed are methods of using FADS1 inhibitors in methods of treating metabolic disorders and obesity.

The invention discloses an euphausia superba oil composition for promoting growth of retinal cells and improving oxidative damage of the retinal cells and application of the euphausia superba oil composition, and belongs to the technical field of functional foods.The euphausia superba oil composition is prepared from, by weight, 0.1-500 parts of euphausia superba oil, 0.1-25 parts of lutein ester and 0.1-5 parts of zeaxanthin; the content of phospholipid in the euphausia superba oil is greater than or equal to 38 wt%, and the content of omega-3 polyunsaturated fatty acid is greater than or equal to 9 wt%. The raw materials of the composition are easy to obtain, the safety is high, retinal cell proliferation can be promoted, the inhibition effect of H2O2 on retinal cells is improved, H2O2-induced high inflammation and high oxidative stress states are relieved, damage of H2O2 to retinal cells is relieved, and the composition has wide application prospects in the aspect of preparing products for optic nerve protection.

There is provided a vegetable-based lipid composition comprising high levels of at least three different long-chain polyunsaturated fatty acids (typically as fatty acid esters). The compositions typically contain DHA as the principal long-chain polyunsaturated fatty acid. The composition is obtainable from a single source by conventional processing methods, and has improved stability properties.