192 results about "Polyunsaturated fatty acid" patented technology

A process produces aliphatic monocarboxylic acids and α,ω-dicarboxylic acids or α,ω-dicarboxylic monoesters by electrochemical oxidation of unsubstituted or at least monosubstituted, monounsaturated or polyunsaturated fatty acids or fatty acid esters in the presence of an inorganic or organic nitrate salt in an electrolysis cell in a reaction medium in the presence of oxygen.

The present invention provides a method for inducing fat accumulation in a cell of a fish, including contacting a cell obtained or derived from a fish with an effective amount of a composition including: (i) a fat accumulation inducing agent; and (ii) a carrier, wherein the fat accumulation inducing agent consists essentially of a free fatty acid and a peroxisome proliferator-activated receptor gamma (PPARy) agonist. Further provided are a cultured fish cell including an increased amount of a PUFA and a reduced amount of MUFA, compared to a control fish cell, and an edible composition including the same.

The invention belongs to the field of food processing, and discloses a preparation method and application of a targeted colon delivery polyunsaturated fatty acid grease microcapsule. 11S globulin in soybeans and Arabic gum are used as wall materials of the microcapsule, complex coacervation of the 11S globulin in the soybeans and the Arabic gum is induced under a certain pH condition, so that oil drops are wetted by a coacervate, a core-shell structure is formed, a coacervate phase is further stabilized through glucan to inhibit coalescence, and on the basis, the microcapsule is prepared. And tannic acid, polysaccharide and protein can form hydrogen bonds and generate hydrophobic interaction to further crosslink the condensed phase to obtain the microcapsule capable of resisting digestion of the stomach and the small intestine, so that colon delivery of polyunsaturated fatty acid is realized.

The invention provides a preparation method of a milk goat total mixed ration containing fresh oat grass, and the method comprises the following steps: preparing a first fermentation product from peanut straw, soybean meal and wheat bran, then carrying out mixed fermentation on the first fermentation product and corn straw to prepare a second fermentation product, and mixing the second fermentation product with other components containing the fresh oat grass to prepare the milk goat total mixed ration. The milk goat total mixed ration provided by the invention can improve the milk yield of milk goats or improve the level of polyunsaturated fatty acids in goat milk.

The invention provides a microalgae fertilizer capable of improving salt and alkali resistance of cucumbers, and the microalgae fertilizer is a composite microalgae bio-fertilizer and comprises scenedesmus obliquus, nitzschia grain and extracellular polymeric substances generated in the culture process of the nitzschia grain. The components of the microalgae compound fertilizer disclosed by the invention are all freshwater algae strains and natural active microalgae cells, so that sodium ions and metal cations cannot be accumulated, the microalgae compound fertilizer does not contain blue-green algae, and cytotoxin which is harmful to the environment cannot be generated; the used algae strains are easier to breed, and the biomass accumulation speed of the algae strains is far higher than that of other algae strains, so that the prepared microalgae biological fertilizer has the advantages of saving time and cost. And the polyunsaturated fatty acid generated by the microalgae fertilizer can enhance the plant resistance through an osmotic regulation system and an antioxidant enzyme ROS system.

The invention belongs to the field of polyunsaturated fatty acid oil preparations, and discloses a steady-state phospholipid type DHA microcapsule as well as a preparation method and application thereof. The preparation method comprises the following steps: weighing resistant dextrin and soybean protein isolate as embedding wall materials according to a certain ratio, uniformly stirring, adding water, stirring and dissolving to form a wall material solution, adding polysaccharide into the wall material solution to obtain a solution A, adding core material grease into the solution A according to a certain ratio, stirring and dispersing, performing high-pressure homogenization to prepare an emulsion, drying, and sieving to obtain the high-temperature-resistant oil-in-oil-in-oil-in-oil-in-oil-in-oil-in-oil-in-oil-in-oil-in-oil-in-oil-in-oil-in-oil. The phospholipid type DHA microcapsule powder is subjected to subcritical treatment, and the steady-state phospholipid type DHA microcapsule powder is obtained. Polysaccharide substances with the molecular weight smaller than 10,000 Daltons are added into an embedding material, stability of polyunsaturated fatty acid grease can be provided, and the prepared phospholipid type DHA microcapsule is free of surface oil, complete in structure, good in taste masking effect, free of fishy smell or similar to fishy smell after being placed for 3 months and excellent in storage stability.

The present invention provides a method for preparing Maillard polyunsaturated fatty acid oil microcapsules. The method for preparing the polyunsaturated fatty acid oil microcapsules comprises the following steps: (1) dissolving sodium caseinate, glucose and lactose in water and mixing them evenly, adding a moisture retaining agent, adjusting the Maillard reaction pH to 8-10, and obtaining an aqueous phase after the reaction; (2) adding polyunsaturated fatty acid oil to the aqueous phase and emulsifying by shearing; (3) adding cellulose and its derivatives to the system obtained in step (2), and shearing to obtain an emulsion; the content of polyunsaturated fatty acid oil in the polyunsaturated fatty acid oil microcapsules is not less than 40wt%. The preparation method provided by the present invention can improve the rehydration property of the Maillard microcapsule product with high oil content, while ensuring that the product is not over-dried, improving the product sensory properties, and ensuring its sensory stability during the shelf life.

The invention provides low-beany-flavor bean flour and a preparation method of low-beany-flavor soybean formula nutrition powder, belongs to the field of food processing, and particularly relates to the preparation method of the low-beany-flavor soybean formula nutrition powder. By providing the low-beany-flavor bean flour and the preparation method of the low-beany-flavor soybean formula nutrition powder, the problems that existing soybean formula nutrition powder is inharmonious in amino acid composition, single in nutrition composition, serious in beany flavor and the like are solved. The soybean formula nutrition powder with low beany flavor and balanced nutrition provided by the invention ensures that an organism obtains comprehensive and balanced amino acid combinations, vitamins, minerals and polyunsaturated fatty acids, and the sensitization is also greatly reduced.

The present invention relates to compounds according to general formula (I) which are metabolically robust analogues of bioactive lipid mediators derived from omega-3 polyunsaturated fatty acids (n-3 PUFAs) for use in treating or reducing the risk of developing or preventing: (i) neovascularization and / or (ii) inflammatory disorder, in particular, ophthalmic disorders associated with neovascularization and / or inflammation.

The invention discloses a preparation method of hippocampus oil, which comprises the following steps: 1) adding dried hippocampus powder into a dichloromethane-methanol mixed solution, uniformly stirring, and extracting for 24 hours; 2) filtering the leach liquor, adding water, fully and uniformly mixing, standing for 12 hours, and collecting a lower layer organic phase; 3, the organic phase is subjected to rotary evaporation drying.The invention further discloses application of the hippocampus oil in preparation of uric acid lowering products.The hippocampus oil is rich in omega-3 polyunsaturated fatty acid (EPA and DHA), the activity of xanthine oxidase is moderately reduced, release of inflammatory factors is inhibited, and the comprehensive effect of inhibiting generation and relieving inflammation is achieved.

The invention provides a functional wet food for improving pet hair health and a preparation method thereof, and belongs to the technical field of pet foods.The functional wet food is prepared from, by weight, 40%-45% of meat, 4%-7% of vegetables, 6%-10% of functional microcapsules, 0.2%-0.5% of mineral additives, 0.3%-0.7% of vitamins, 0.5%-1% of natural humectants and the balance deionized water. The functional microcapsule prepared by coating the polyunsaturated fatty acid and the traditional Chinese medicine extract with the chitosan can enhance the stability of the polyunsaturated fatty acid and the palatability of wet grains, and meanwhile, the polyunsaturated fatty acid and the traditional Chinese medicine extract in the microcapsule can achieve a synergistic effect, so that the skin and hair states of pets are improved from inside to outside.

The name of the invention is a pharmaceutical combination for the treatment of cancer. A pharmaceutical combination comprising (A): a polyunsaturated fatty acid and (B): a chemotherapeutic compound for simultaneous, separate or sequential use in the treatment of cancer in a human patient.

The present invention provides a kind of composition containing bird's nest acid, phospholipid and polyunsaturated fatty acid and preparation method thereof, composition, when not adding any additives, bird's nest acid is dispersed in DHA grease in functional ingredients, while solving the problem that DHA is easily oxidized, promotes brain development, regulates immunity, promotes the absorption and utilization of minerals in the intestine and the effects of beauty and skin care. Phospholipids can prevent the sedimentation of bird's nest acid in ω 3 polyunsaturated fatty acid grease, and are phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol or phosphatidylserine. Not only can the sedimentation of bird's nest acid be prevented, but also the growth of nerve cells can be supported, thereby improving the absorption rate of DHA in the brain. Especially PS, itself can not only nourish the brain, enhance brain function, but also relieve mental stress and improve cognition, and is called "brain nutrient".

The invention provides paeonia suffruticosa-derived phosphatidyldiacylglycerol acyltransferase 1-2 or a coding gene and application thereof, and belongs to the technical field of functional proteins. The invention relates to phosphatidyldiacylglycerol acyltransferase 1-2 from paeonia ostii, which comprises phosphatidyldiacylglycerol acyltransferase 1-2 from paeonia ostii and / or phosphatidyldiacylglycerol acyltransferase 1-2 from paeonia suffruticosa. Experiments show that the Paeonia ostii-sourced phosphatidyldiacylglycerol acyltransferase 1-2 and / or Paeonia fulva-sourced phosphatidyldiacylglycerol acyltransferase 1-2 not only can synthesize linoleic acid and alpha-linolenic acid by using exogenous polyunsaturated fatty acid, but also does not affect accumulation of yeast total lipid. The peony-sourced phosphatidyldiacylglycerol acyltransferase 1-2 provided by the invention provides a new method for biosynthesis of triacylglycerol, and provides a new way for genetic breeding of oil crops.

Disclosed herein is a refined PUFA oil with an enhanced palatability comparing to the same PUFA oil without refinement. Also disclosed is a food composition for a companion animal or a food for human consumption wherein said food composition comprises the above refined PUFA oil and thus having enhanced palatability. Further disclosed herein is a method for manufacturing the above-mentioned refined PUFA oil wherein said method comprises the step of deodorization.

The invention provides new application of lauric acid, and researches on the inhibiting effect of lauric acid on a cardiac voltage gated sodium channel Nav1.5 and the action mode of lauric acid in electrophysiological conduction prove that natural polysaturated fatty acid lauric acid is a potential Nav1.5 sodium channel inhibitor for the first time. Electrophysiological characterization shows that lauric acid is the most effective monomer in natural polysaturated fatty acid screened for inhibiting Nav1.5, and the IC50 value is 27.40 + / -12.78 mu M.

The invention discloses polyunsaturated fatty acid microcapsule powder as well as a preparation method and application thereof, and belongs to the field of foods. The microcapsule powder comprises the following raw materials: a core material solution prepared from 10-25% of polyunsaturated fatty acid and 0.5-2% of an emulsifier, and a wall material solution prepared from 2-5% of sodium caseinate, 3-6% of reducing sugar, 15-25% of modified starch and 40-60% of distilled water through heating and stirring. Wherein the mass ratio of the polyunsaturated fatty acid to the wall material is (1: 1.2)-(1: 1.5); and mixing the wall material solution and the core material solution, stirring and shearing, homogenizing and emulsifying at high pressure, sterilizing, and spray-drying to obtain the polyunsaturated fatty acid microcapsule powder. According to the present invention, the fishy smell of the polyunsaturated fatty acid can be covered, and effects of high oil loading capacity, high oxidation stability, high absorption rate, simple process and low cost are provided.

The utility model discloses homogenizing equipment for processing polyunsaturated fatty acid-based antioxidant cream, which relates to the related field of cream processing equipment and comprises a tank body, a base is mounted at the bottom of the tank body through bolts, a feeding pipe is mounted on a perforated pipeline at the top of the tank body, and an auxiliary stirring component is arranged at the left end of the outer side surface of a stirring shaft at the bottom of a stirring motor. The stirring motor drives the stirring plate, the through plate and the guide plate to stir ingredients in the tank body, so that the ingredients collide with one another through the through plate and the through hole to accelerate mixing, and the ingredients in the tank body are upwards or downwards rushed out through the rotating guide plate; the material cleaning assembly is arranged at the left end of the inner side face of the tank body, when a scraping plate makes contact with the inner wall of the tank body, generated counter-acting force drives a sliding rod to compress a spring, in this way, cream adhering to the inner wall or the inner bottom of the tank body can be scraped away through the scraping plate and a material guide disc, and the scraped cream can be concentrated, gathered and discharged through the material guide disc.

The present embodiments provide a plant-based lipid composition comprising high concentrations of long-chain omega-3 fatty acids, typically as fatty acid esters, comprising DPA, DTA, ETA, or ETrA, optionally with OA or ALA. These enriched lipid compositions have improved stability, and offer a sustainable source for these long-chain omega-3 fatty acids. In some embodiments, these enriched lipid compositions show enhanced modulation of inflammatory markers, such as inhibition of inflammatory cytokines, and offer nutritional or therapeutic value..

This invention discloses a microfluidic method for preparing fish oil microspheres based on viscosity control and its application, belonging to the field of functional food preparation technology. The method involves constructing three viscosity systems (3.47–15.19 mPa·s) by compounding concentrated fish oil and castor oil at a specific volume ratio. Using a 3% polyvinyl alcohol aqueous solution as the continuous phase, water-in-oil fish oil microspheres are prepared under constant pressure in a cross-shaped microfluidic chip. By controlling the viscosity of the oil phase, the microsphere particle size can be precisely controlled within the range of 53.89–72.34 μm, with a coefficient of variation ≤5% and regular morphology. The obtained microspheres exhibit excellent particle size stability under pH 5–7 and 0–2% NaCl conditions. The high-viscosity microspheres show significantly lower acid values ​​and thiobarbituric acid reactant values ​​compared to the low-viscosity group under storage conditions of 4–60℃, with an oxidation stability improvement of over 30%. In vitro digestion experiments show that the low-viscosity microspheres reach peak free fatty acid release rate after 120 min, while the high-viscosity group exhibits a sustained-release effect. This invention achieves simultaneous optimization of fish oil microsphere particle size, stability, and digestive behavior, providing a theoretical basis and precise process parameters for the structured design of ω-3 polyunsaturated fatty acid functional foods.

The invention relates to the field of microalgae active component extraction, and discloses a method for extracting fucoxanthine and polyunsaturated fatty acid from microalgae and an extracted product thereof, the method comprises the following steps: S1, carrying out first extraction on the microalgae by using a low-concentration alcohol solution, and carrying out solid-liquid separation to obtain a first algae cake and a first extracting solution; and S2, carrying out second extraction on the first algae cake obtained in the step S1 by using a high-concentration alcohol solution, and carrying out solid-liquid separation to obtain a second algae cake and a second extracting solution. According to the method, the low-concentration alcoholic solution and the high-concentration alcoholic solution are matched for extraction, the method is simple, efficient, low in cost and suitable for large-scale production, the problem of residues of toxic solvents such as n-hexane is avoided, the alcoholic solution can be recycled, the proportion of the low-concentration alcoholic solution and the high-concentration alcoholic solution in a final finished product is close to that in natural microalgae cells, and the method is suitable for large-scale production. And the composition does not need to be compounded again.

The invention provides a senescent muscle repairing composition and application, and belongs to the technical field of cosmetics. Comprising polyunsaturated fatty acid, carotenoid, peptides, polydeoxyribonucleotide PDRN and at least one algae extract selected from chlorella, spirulina, brown algae and red algae. According to the senescent muscle repairing composition prepared by the invention, through a carefully selected natural active component system, the composition has a synergistic effect from two major directions of promoting synthesis of ECM key components and inhibiting excessive degradation of ECM, and improves the structural quality of ECM, so that the steady state of skin ECM is effectively recovered, and the purposes of improving wrinkles and improving compactness and elasticity are achieved.

The present disclosure provides techniques for assessing FADS1 activity in a patient. Also provided are techniques for determining the appropriateness of treating a patient with a FADS1-modulating (e.g., inhibiting) compound. This determination can be made by analyzing one or more biological indicators of a FADS1-mediated disease or disorder in the subject. The one or more biological indicators can include one or more of the following in the subject: ratios of polyunsaturated fatty acids ("PUFAs"), the relative abundance of one or more cell types, the relative abundance of one or more differentially expressed genes ("DEGs") (or gene signatures of such DEGs, e.g., RNA), and / or the relative abundance of one or more metabolites. Also disclosed are methods of using FADS1 inhibitors in methods for treating metabolic disorders and obesity.

The invention discloses a method for preparing vegetarian whole eggs based on lotus seed resistant starch-protein-based oil body emulsion filling gel, and belongs to the field of food processing. According to the vegetarian whole egg prepared by the invention, the selected raw materials are high in nutritional value, and yeast protein and soy isolate protein are compounded to simulate the protein content and amino acid characteristics in natural egg white; the oil body is rich in lecithin and polyunsaturated fatty acid so as to simulate high-quality fat and color of yolk; lotus seed resistant starch is RS3 type resistant starch capable of relieving allergy, and it is found that the lotus seed resistant starch can improve the gel characteristic in a certain concentration range so as to be matched with the egg texture. The method disclosed by the invention is simple in processing technology, green and environment-friendly, vegetarian whole eggs with nutrient composition, texture and color similar to those of eggs are obtained, and a diversified nutritional supplement is provided for egg allergic persons and vegetarian persons.

The application belongs to the technical field of microbial fermentation, and particularly relates to a fermentation product of fruit and vegetable wastes and corn stalks and application thereof. The fermentation product is obtained by inoculating Aspergillus oryzae SLY-M-15 fermentation product and Saccharomyces cerevisiae into a first mixture containing crushed and air-dried corn stalks and fruit and vegetable wastes, performing aerobic fermentation, adding a second mixture containing crushed and air-dried corn stalks and fruit and vegetable wastes and corn cob, performing secondary aerobic fermentation, inoculating Lactobacillus casei, Lactobacillus acidophilus and Lactobacillus fermentum, and performing anaerobic fermentation. The obtained fermentation product is applied to animal feed, can improve the average daily weight gain of mutton sheep, reduce the feed conversion ratio, improve the tenderness and cooked meat rate of mutton, and increase the content of n-3 polyunsaturated fatty acids.

The present disclosure provides techniques for accessing FADS1 activity in a patient. Also provided are techniques for determining the appropriateness of treatment of a patient with a FADS1 modulating (e.g., inhibiting) compound. This determination may be made by analyzing one or more biological indicators of FADS1-mediated disease or disorder in the subject. The one or more biological indicators may include one or more of a ratio of polyunsaturated fatty acids (“PUFAs”) in the subject, a relative abundance of one or more cell types, a relative abundance of one or more differentially expressed genes (“DEGs”) (or gene signatures, such as RNA, for such DEGs), and / or a relative abundance of one or more metabolites. Also disclosed are methods of using FADS1 inhibitors in methods of treating metabolic disorders and obesity.

A method for preparing a filled chocolate product, the method comprising: providing a filling composition comprising at least one powdered food ingredient and a fat blend comprising from 15 to 67 wt.% of a temper hard fat and from 85 to 33 wt.% of a liquid oil, tempering the filling composition to form a tempered filling composition, depositing the tempered filling composition on to at least one surface of a chocolate product, wherein the surface of the chocolate product has a temperature of less than 28 ºC, and optionally coating the filling composition with chocolate, actively cooling the deposited filling composition, wherein in the step of depositing the tempered filling composition, the tempered filling composition is deposited having a temperature of from 20 to 30 ºC and in the step of actively cooling the deposited filling composition, the deposited filling composition is cooled to a temperature of at least 4 ºC below the deposition temperature, wherein the temper hard fat has a solid fat content of at least 60 wt.% at 20 ºC, wherein the liquid oil has a solid fat content of less than 15 wt.% at 20 ºC, and wherein the fat blend has a saturated fatty acid residue content of from 16 to 42 wt.% and a polyunsaturated fatty acid residue content of less than 40 wt.%, based on the total weight of fatty acid residues of the fat blend.

Disclosed are cosmetic compositions and skin care products that are stabilized against lipid chain auto-oxidation. In particular, this invention substitutes a portion of polyunsaturated fatty acids used in cosmetic compositions and skin care products with a corresponding deuterated polyunsaturated fatty acid.

There are provided compositions comprising at least one compound chosen from compound of formula (I), compound of formula (II), compound of formula (III) and compound of formula (IV); and a cannabinoid for use as a COX-2 inhibitor.