69 results about "Fatty acids.polyunsaturated" patented technology

The invention discloses a method for screening carp dominant parents with high total polyunsaturated fatty acid content. The method comprises the steps that training feature data and training target data are obtained, the training feature data comprise SNP genotype information of a training sample, and the training target data comprise polyunsaturated fatty acid total content information of the training sample; training the ridge regression model by using the training feature data and the training target data to obtain a prediction model; obtaining SNP genotype information of a to-be-detected sample; obtaining a breeding value of the to-be-detected sample according to the SNP genotype information of the to-be-detected sample and the prediction model; and screening the carp dominant parents with the total content of polyunsaturated fatty acids according to the breeding values. According to the method, the breeding value of the carp can be directly obtained according to the SNP genotype information of the sample to be detected and the prediction model, so that dominant parents with high carp polyunsaturated fatty acid content are screened from the sample to be detected, and an excellent material is provided for new carp germplasm identification and breeding.

The disclosure provides methods for increasing saturated, monounsaturated, and poly unsaturated fatty acid production using the PUFA gene cluster plasmid and the gene regulator pfaR.

The application discloses a method for screening superior parents of carp with high total content of polyunsaturated fatty acids. The method comprises obtaining training characteristic data and training target data, wherein the training characteristic data comprises SNP genotype information of training samples, and the training target data comprises total content information of polyunsaturated fatty acids of the training samples; training a ridge regression model by using the training characteristic data and the training target data to obtain a prediction model; obtaining SNP genotype information of a to-be-tested sample; obtaining a breeding value of the to-be-tested sample according to the SNP genotype information of the to-be-tested sample and the prediction model; and screening superior parents of carp with high total content of polyunsaturated fatty acids according to the breeding value. By the method, the breeding value of the to-be-tested sample can be directly obtained according to the SNP genotype information of the to-be-tested sample and the prediction model, and then the superior parents of carp with high content of polyunsaturated fatty acids can be screened from the to-be-tested sample, thereby providing excellent materials for new germplasm identification and breeding of carp.

This invention relates to the field of fatty acid detection technology, specifically to a method for determining 11 polyunsaturated fatty acids based on LC-MS / MS. The method includes: preparing a calibration solution; hydrolyzing bound fatty acids in a blood sample, adding a precipitant, centrifuging, and collecting the supernatant as the test sample; detecting the test sample using liquid chromatography-tandem mass spectrometry, and substituting the detection results into the calibration curve equation to obtain the content of the 11 polyunsaturated fatty acids in the test sample. This method can rapidly and accurately detect the content of 11 polyunsaturated fatty acids, providing a more accurate basis for clinical diagnosis and assisting in the early detection and treatment of diseases; at the same time, it can also provide more targeted nutritional advice to individuals, promoting health management.

To provide a means effective in suppressing oxidative deterioration of fats and oils containing polyunsaturated fatty acid containing DHA and to provide a method capable of determining near olfactory sense of human being by specifying a component that becomes an index of oxidative deterioration of fat and acid containing DHA.SOLUTION: A lipid composition containing lipids composed of polyunsaturated fatty acids as constituent fatty acids, wherein a composition ratio of polyunsaturated fatty acids among all constituent fatty acids of the lipids is 15% or more, the moisture content is 600 ppm or less, perfluorooctanesulfonic acid is 0.1 ppb or less, and perfluorooctanoic acid is 0.1 ppb or less. It is preferable that the composition contains 2-(2-pentenyl)furan at less than 0.0095 ppm, and 2,4-heptadienal at less than 2.600 ppm.SELECTED DRAWING: None

Deuterated polyunsaturated fatty acid (“PUFA”) compounds, compositions, and uses of the compounds for reducing lipid autooxidation and the treatment of various diseases and conditions are provided.

The invention provides a method for producing polyunsaturated fatty acid, and belongs to the technical field of biological fermentation. The method for producing polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid from schizochytrium limacinum comprises the following steps: activating schizochytrium limacinum in a seed culture medium to obtain a schizochytrium limacinum seed culture solution; inoculating the schizochytrium limacinum seed culture solution into a fermentation culture medium for culturing, wherein the fermentation culture medium comprises rapeseed protein powder; and extracting the culture solution in the cultured fermentation culture medium to obtain the polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid. According to the present invention, the yield of polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid can be significantly improved.

Fatty acids with one or more unsaturations and an odd-numbered hydrocarbon chain are described, wherein these fatty acids have the chemical structure of the therapeutically active metabolites of alpha-hydroxylated mono- or polyunsaturated fatty acids with an even-numbered chain. The compositions comprising these fatty acids, their medical uses, and their use as indicators of a patient's efficacy and / or response to treatment with the alpha-hydroxylated mono- or polyunsaturated fatty acids with an even-numbered chain from which they are derived are also described.

This invention relates to a method for rapidly screening filamentous fungi that produce high levels of triglycerides and polyunsaturated fatty acids, belonging to the field of microbial technology. The method employs a two-stage screening strategy of "resistance primary screening – fluorescence secondary screening." In the primary screening stage, strains with strong lipid synthesis capabilities are initially screened by adding a combination of phytocyanin and quizalofop-p-ethyl inhibitors to the culture medium. In the secondary screening stage, cellophane culture technology and Nile red fluorescence staining are combined to quantitatively assess the triglyceride content of the colonies, achieving rapid and non-destructive screening. This method is simple to operate, highly efficient, and shows a significant positive correlation between fluorescence intensity and triglyceride content. It is suitable for mutagenesis breeding and industrial strain selection of oil-producing filamentous fungi such as *Morchella alpineensis*.

PROBLEM: To provide a composition comprising highly enriched PUFA or its alkyl esters while containing fatty acid esters of 3-MCPD at adequately low concentrations and to provide an efficient method for producing the composition. MEANS FOR SOLVING: A composition that contains fatty acids or fatty acid alkyl esters as its major component, the composition containing highly unsaturated fatty acid or alkyl ester thereof, wherein the proportion of the highly unsaturated fatty acid in the constituent fatty acids of the composition is 50 area % or more and wherein the concentration of 3-MCPD as found upon analyzing the composition by American Oil Chemists' Society official method Cd 29b-13 assay A is less than 1.80 ppm.

The invention provides a feed additive for increasing the content of n-3 polyunsaturated fatty acids in pork and a compound feed. The feed additive consists of spartina alterniflora powder and a bacterial enzyme additive, the bacterial enzyme additive is prepared from lactobacillus plantarum, aspergillus niger, yarrowia lipolytica, bacillus subtilis, cellulase, beta-mannase and protease; the compound feed comprises a basic ration and the feed additive. Through development and utilization of spartina alterniflora powder and practice, waste is turned into wealth, a new source of the feed additive is expanded, and the feed additive is added into daily ration, so that the digestibility of neutral detergent fibers of the daily ration is improved, the antioxidant capacity of serum is enhanced, and the contents of alpha-linolenic acid, arachidonic acid and eicosapentaenoic acid in pork are increased.

Genetically engineered yeast cells having disruption of pex3, pex5 or pex20 genes and combinations thereof having reduced beta-oxidation and methods for increasing polyunsaturated fatty acids are disclosed.

The present application relates to the technical field of microcapsules, and in particular to a polyunsaturated fatty acid oil microcapsule, a preparation method therefor, and a use thereof. The present application provides a polyunsaturated fatty acid oil microcapsule, the raw material of which comprises polyunsaturated fatty acid oil, wherein an anisidine value of the polyunsaturated fatty acid oil is not greater than 10. It is found in the present application that the anisidine value of the polyunsaturated fatty acid oil will affect the solubility of the microcapsule containing the polyunsaturated fatty acid oil, and the solubility of the polyunsaturated fatty acid oil microcapsule can be effectively improved by controlling the anisidine value of the polyunsaturated fatty acid oil within a range of not higher than 10, thereby solving the problems that a product containing the polyunsaturated fatty acid oil microcapsule has poor solubility and is prone to generation of insoluble particles, and improving the quality of the product containing the polyunsaturated fatty acid oil microcapsule.

To provide an oil which does not become cloudy when stored at a low temperature while containing a specific amount of palmitic acid.SOLUTION: An oil containing a specific amount of palmitic acid has at least one characteristic selected from the group consisting of (i) a predetermined triglyceride content, (ii) a predetermined PUFA content, (iii) a predetermined stearic acid content, (iv) a predetermined content of C18 fatty acids, and (v) a predetermined DHA / EPA ratio. The oil does not become cloudy during low-temperature storage.SELECTED DRAWING: Figure 1

A frozen aerated confection comprising water and a fat component, wherein the fat component is present in an amount of from 1 to 15 wt%, and wherein the fat component comprises i) a fat blend having a triglyceride composition of from 30 to 80% saturated fatty acids, less than 30% polyunsaturated fatty acids and the remainder being monounsaturated fatty acids, and ii) a wax ester.

The present invention belongs to the technical field of oil refining, and specifically relates to a method for removing mineral oil from oil and fat, and the resulting oil and fat. The method comprises the following steps: introducing steam into the oil and fat under vacuum conditions for treatment; wherein the total amount of steam introduced is 15% to 95% of the mass of the oil and fat. The method for removing mineral oil from oil and fat provided by the present invention is particularly advantageous for removing mineral oil from polyunsaturated fatty acid oils and fats. It can effectively and simply remove mineral oil from oil and fat without changing the existing oil and fat production process steps, and obtain oil and fat with a mineral oil content of less than 5 ppm.

The present invention belongs to the field of dairy cow performance measurement and milk quality detection, and discloses a method for rapid batch detection of polyunsaturated fatty acids in milk by mid-infrared spectroscopy. In terms of the selection of characteristic bands, it breaks the commonly used method of using algorithms to screen features, and instead uses a method of manual selection + multiple traversals. Finally, characteristic bands for modeling are selected, especially the absorption region containing part of water is screened out, and it is proved that adding part of the water absorption band can improve the accuracy of the model. The optimal preprocessing and algorithm combination for the establishment of the polyunsaturated fatty acid model is selected, the optimal parameters are determined, and the accuracy of the model is improved. Rapid, accurate, and low-cost detection of the polyunsaturated fatty acid content in raw milk is achieved, and rapid batch detection is realized.

The application provides a polyunsaturated fatty acid oil microcapsule and a preparation method. The preparation method of the polyunsaturated fatty acid oil microcapsule comprises the following steps: (1) adding a water retention agent into an aqueous solution of a water-soluble protein wall material, and uniformly mixing to obtain an aqueous phase; (2) adding polyunsaturated fatty acid oil into the aqueous phase, and shearing and emulsifying; (3) adding cellulose and a derivative thereof into the system obtained in the step (2), and shearing to obtain an emulsion; the content of the cellulose and the derivative thereof in the polyunsaturated fatty acid oil microcapsule is 0.05-0.3 wt%; the content of the polyunsaturated fatty acid oil in the polyunsaturated fatty acid oil microcapsule is not less than 40 wt%, and the content of a fatty acid with a carbon chain length of more than 20 and an unsaturated double bond of more than 4 in the polyunsaturated fatty acid oil is not less than 40%. The high oil-loading microcapsule product obtained by the preparation method has good sensory and good stability during a shelf life.

The application provides a medicine for treating an immune checkpoint inhibitor-resistant tumor, comprising a polyunsaturated fatty acid, an ACLY inhibitor and an immune checkpoint inhibitor. The polyunsaturated fatty acid comprises one or more of omega-3 polyunsaturated fatty acids and omega-6 polyunsaturated fatty acids. The ACLY inhibitor is selected from one or more of the following: Bempedoic acid, SB 204990, NDI-091143, BMS-303141, small interfering RNA targeting the ACLY gene and short hairpin RNA targeting the ACLY gene. The medicine has good treatment effect on the immune checkpoint inhibitor-resistant tumor.

A method of preparing rumen-protected polyunsaturated fatty acids (RuPUFAs) for use in ruminant feeds by inducing the Maillard reaction between a reducing carbohydrate source and de-oiled lecithin in the presence of a PUFA under reduced pressure conditions is disclosed. Products made by the process, as well as methods for enhancing performance, assisting the induction of pregnancy, alleviating inflammation, modulating fetus growth, improving immune system function, and modulation of the fatty acid composition of meat and milk of ruminant animals are also disclosed.

The present invention relates to a process for producing ethyl esters of polyunsaturated fatty acids, comprising transesterifying triacylglycerols in extracted plant lipid.

Disclosed herein are methods for preparing isotopically modified polyunsaturated lipids containing 1,4-diene systems, comprising selective isotopic modification of one or more bis-allylic positions of the polyunsaturated lipid in the presence of a transition metal catalyst.

The invention belongs to the technical field of food processing, and particularly relates to a preparation method of thymol microemulsion and application of the thymol microemulsion in margarine. According to the thymol microemulsion provided by the invention, the water solubility and stability of edible oil and the utilization rate of unsaturated fatty acid can be improved, the edible oil is encapsulated in the form of microemulsion, and polyunsaturated fatty acid is embedded through a food delivery system, so that the dispersity of the polyunsaturated fatty acid in a water phase is improved, and oxidation of oil drops is inhibited; therefore, the purposes of protecting, transferring and releasing the functional grease are achieved. According to the margarine prepared by the preparation method disclosed by the invention, in-vitro simulated digestion result analysis shows that oil drops of a test sample are gradually reduced along with the action of stomach and intestine digestive juice, and the total fatty acid content is reduced. According to the phenomenon, positive regulation and control of a system on fat digestion and normal metabolism of fat are optimized, the controllability of fat digestion and absorption is achieved, the requirements of special crowds for slow release of nutritional ingredients of sugar-controlled and fat-controlled people and the like are met, and experimental and theoretical support is provided for functional application.

The invention belongs to the technical field of meat product processing, and discloses a composite nutrition enhancer for a meat product, a nutrition-enhanced meat product and a processing method of the nutrition-enhanced meat product. The composite nutrition enhancer for meat products is an oil-in-water type emulsion, and is prepared by emulsifying the following raw materials: konjac gum gel liquid, which is a gel dispersion liquid obtained by heating konjac gum under an alkaline condition to form gel, neutralizing the gel, and shearing and dispersing the gel; the edible oil and fat is rich in Omega-3 polyunsaturated fatty acid; the invention discloses a jack fruit seed coat extract. The compound nutrition enhancer and the meat product enhanced by the compound nutrition enhancer provided by the invention can still keep an extremely low grease oxidation degree (for example, the peroxide value is obviously lower than that of a control group) and an extremely high nutrient retention rate after being subjected to freeze thawing, heating and long-term storage, so that the most difficult problem of instability in Omega-3 enhancement is fundamentally solved.

The present invention relates to the production of aromatic hexanols and compositions containing them. In particular provided herein are methods of producing hexenols comprising: a) contacting a hydroperoxide of a polyunsaturated fatty acid with a modified hydroperoxide lyase to form a hexenal; and b) reducing the hexenal to a hexenol in the presence of a hydride donor, a ketoreductase, and a co-factor wherein the contacting and reducing steps are carried out at essentially the same time in the substantial absence of baker's yeast.

The invention discloses a method for preparing high-purity cis-oleic acid through selective hydrogenation of vegetable oleic acid, and belongs to the technical field of preparation of cis-oleic acid. Comprising the following steps: dissolving vegetable oleic acid in a solvent to form a mixed solution, and then introducing the mixed solution and mixed gas consisting of hydrogen and inert gas into a fixed bed reactor filled with a PdPt / C catalyst for hydrogenation reaction, thereby realizing selective hydrogenation of the vegetable oleic acid to generate high-purity cis-oleic acid. By accurately regulating and controlling the partial pressure of hydrogen in the mixed gas and the polarity type of the solvent, polyunsaturated fatty acids such as linoleic acid and the like can be efficiently hydrogenated, meanwhile, side reactions that oleic acid is excessively hydrogenated into stearic acid and a cis-structure is converted into a trans-isomer are remarkably inhibited, and finally, a cis-oleic acid product with high purity and high yield is obtained.

The present invention relates to a novel enzyme capable of producing multi-hydroxy derivatives from polyunsaturated fatty acids and a method for producing multi-hydroxy derivatives of polyunsaturated fatty acids using the same.

The present invention relates to compounds according to general formula (I) which are metabolically robust analogues of bioactive lipid mediators derived from omega-3 polyunsaturated fatty acids (n-3 PUFAs) for use in treating, reducing the risk of developing or preventing a disorder associated with an elevated GDF-15 plasma concentration.

The invention relates to the technical field of feed additives. The invention provides a composition for producing selenium-enriched snowflake beef, a functional feed additive prepared from the composition and application of the functional feed additive. Comprising rapeseed oil, soybean oil, palm oil, linseeds, fructus perillae, semen raphani, platycladus orientalis kernels, fennel, fructus psoraleae, pumpkin seeds, semen cassiae, fructus arctii, semen plantaginis, common fenugreek seeds, semen cuscutae, fructus cnidii, cardamine violifolia powder, cortex magnoliae officinalis, cortex cinnamomi, haws, pericarpium citri reticulatae, pericarpium citri reticulatae viride, rhizoma atractylodis, cyrtomium fortunei, herba artemisiae scopariae, bile acid, soybean phospholipid, cellulase, fatty acid synthetase, vitamin E, vitamin D, zeolite powder and the like. Lipase, polyunsaturated fatty acid, phytoestrogen and the like contained in the traditional Chinese veterinary medicine seeds are utilized to regulate fat metabolism of an organism and increase the content of high-density lipoprotein, and traditional Chinese veterinary medicines for warming and nourishing liver and kidney and soothing liver-gallbladder are fused to enhance liver and kidney functions of the organism, increase biliary secretion and cooperatively promote digestion and absorption of lipid and formation of snowflake beef.