5 results about "Host organism" patented technology

This invention discloses a mass spectrometry patch for wound infection detection and its application, relating to the field of biomedical device technology. The mass spectrometry patch consists of a contact layer, a collection layer, and a protective layer from bottom to top. The contact layer is a polycarbonate mesh film, the collection layer is a polyvinylidene fluoride nanofiber membrane with high-density gold nanoparticles grown in situ on its surface, and the protective layer is a polyurethane film. This invention provides a wearable mass spectrometry patch integrating sampling and detection, achieving non-invasive sampling and direct mass spectrometry analysis. A single detection using laser desorption / ionization mass spectrometry can obtain a global metabolic fingerprint containing hundreds of metabolites, which simultaneously contains pathogen species-specific signals and host metabolic biomarker signals. By training an AI model to analyze the complex fingerprint, rapid pathogen identification and dynamic monitoring of host responses (such as lactic acid and glucose) can be completed simultaneously within 5 minutes, achieving decoupling of pathogen information from changes in host biomarkers.

The invention relates to methods for detecting and quantifying the presence of an organism in a sample, typically for detecting and quantifying the presence of a non-host organism in a host, and kits providing components useful for performing such methods. The invention also relates to methods for monitoring the effectiveness of a treatment of a disease or infection associated with a pathogen in a host. The invention further relates to methods for treating a disease or an infection associated with a pathogen in a host. The invention additionally relates to a computer program and to a computer-readable storage medium, comprising instructions causing a computer to carry out the method of the invention.

This document discloses methods for producing interfering RNA (RNA) biopesticides, such as microbial host organisms engineered to produce interfering RNA molecules that inhibit gene expression in disease-carrying mosquitoes through RNA interference. This document also discloses polynucleotides, such as expression cassettes encoding these interfering RNA molecules and facilitating integration (e.g., stable integration) into the host organism's genome. This document further discloses compositions comprising the disclosed nucleotide sequences and a host organism, and methods for using them to control mosquito populations.

In some other conventional carminic acid production methods, carminic acid production may be carried out within a host organism and / or cells. The present invention relates to materials and methods for the production of carminic acid from substrates. The present invention provides methods and materials for cell-free bioproduction of carminic acid. The methods provided in the present invention relate to cell-free production of carminic acid that is more economical and reliable compared to other conventional carminic acid production methods. Furthermore, the methods provided in the present invention provide carminic acid from these processes that offers higher potency compared to carminic acid produced by other conventional methods.

The present disclosure provides patterned biomaterials having organized cords and extracellular matrix embedded in a 3D scaffold. According, the present disclosure provides compositions and applications for patterned biomaterials. Pre-patterning of these biomaterials can lead to enhanced integration of these materials into host organisms, providing a strategy for enhancing the viability of engineered tissues by promoting vascularization.