50 results about "Pathogen resistance" patented technology

The invention discloses a chelerythrine-containing compound microbial agent and application thereof, and belongs to the technical field of biological control. The invention provides a chelerythrine-containing compound microbial agent to solve the technical problems that in the prior art, only a single microbial agent and a plant extract are used, the biological control effect is poor, the stability is low, and the target spot is single. The compound microbial agent is prepared from a mortierella alpina extract, a trichoderma hairy extract and chelerythrine according to a specific compounding ratio. The compound microbial agent provided by the invention can delay the development of drug resistance of pathogenic bacteria through a multi-target effect, has better stability and stronger control effect, reduces the use amount of chemical pesticides, reduces the harm to the environment and human body, can be applied to tobacco planting production, can effectively reduce the control cost of tobacco black shank, and has broad application prospects. The economic benefit of tobacco planting is improved.

Methods and compositions for identifying, selecting and / or producing a pathogen resistant plant, plant cell or seed (e. g,, a maize plant, plant cell or seed) are provided. Polynucleotides and polypeptides are provided, which when expressed in a plant increase disease and / or pathogen resistance (e.g., to Fusarium stalk rot) of the plant. Plants, plant cells and seed are provided comprising such polypeptides and polynucleotides, as are methods for their use.

By engineering genetic traits associated with photosynthesis in plants, transgenic plants with increased crop yield can be generated, which will ultimately lead to increased food production in the field. To obtain beneficial genetic traits for enhanced photosynthesis, accelerated evolution is applied under salt stress in a cyanobacteria species, Synechococcus elongatus PCC 7942, by conditionally suppressing its mismatch repair system. Through high-throughput screening for biomass accumulation and sucrose production, it is discovered that specific amino acid changes in the pre-Dl protein of Photosystem II (PSII), encoded by the psbA genes, can improve efficiency of photosynthesis under salt stress, as well as pathogen resistance. Next, the same amino acid changes were made in Arabadopsis and proved that photosynthetic efficiency (measured via growth rate) is also increased in this model vascular plant.

Synthetic Southern Phaseoloviridae satellite RNA molecules and satellite particles containing the same are disclosed. Synthetic Southern Phaseoloviridae satellite RNA molecules containing an internal heterologous RNA virus (HRV) amplicon are also disclosed. Also disclosed are methods of using Southern Phaseoloviridae satellite RNA molecules and satellite particles containing the same to alter plant phenotypes, improve stress resistance in plants, and improve pest and pathogen resistance in plants.

Methods and compositions for identifying, selecting and / or producing a pathogen resistant plant, plant cell or seed (e.g., a legume or soybean plant, plant cell or seed) are provided. Polynucleotides and polypeptides are provided, which when expressed in a plant increase disease and / or pathogen resistance (e.g., to Asian Soy Rust) of the plant. Plants, plant cells and seed are provided comprising such polypeptides and polynucleotides, as are methods for their use.

Disclosed are synthetic Marivirus eye satellite RNA molecules and satellite particles containing the same. Also disclosed are synthetic mateur virus satellite RNA molecules containing an internal heterologous RNA virus (HRV) amplicon. Also disclosed are methods of altering plant phenotypes, improving stress resistance in plants, and improving pest and pathogen resistance in plants using the Marivirus eye satellite RNA molecules and satellite particles containing the same.

The invention relates to the technical field of pesticide compounding, and discloses a bactericidal compound composition containing quinolone compounds and application thereof. The composition comprises effective active components, the effective active components comprise a compound I and a compound II, the compound I is 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid-2-methoxyethyl ester, and the compound II is other compounds with bacterial killing activity, and the compound I and the compound II are selected from the group consisting of 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid-2-methoxyethyl ester and 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid-2-methoxyethyl ester. The bactericidal compound composition disclosed by the invention has the following advantages: (1) the bactericidal compound composition has a synergistic effect and can improve the prevention and treatment effect; (2) the bactericidal spectrum is expanded, field diseases are mixed, and the effect on bacterial diseases is stronger; (3) the two effective components are mixed for use, so that the drug resistance of pathogenic bacteria can be delayed; and (4) the application amount is reduced, the use frequency is reduced, and the use cost is reduced.

This invention relates to a method for risk assessment of multiple ecological factors in lakes based on DOM (Dissipative Oxygen Species), nutrients, and the coupling of functional bacteria and pathogen resistance. The invention aims to address the technical problems of current lake risk assessment methods, which primarily focus on evaluating single resistance risks, neglect the ecological buffering role of functional bacteria, and fail to reflect the coupled risks of multiple ecological factors in lakes. This invention obtains DOM parameters, nutrient parameters, functional bacteria indicators, pathogenic bacteria indicators, and drug resistance transmission factor indicators; calculates a comprehensive risk value R based on the environmental stress index E, ecological buffering index B, transmission hazard index H, and DOM-mediated transmission triggering coefficient K, and performs risk classification and spatial zoning assessment. This invention incorporates DOM activity, nutrient imbalance, the ecological buffering capacity of functional bacteria, and the drug resistance transmission potential of pathogenic bacteria into a unified evaluation framework, applicable to comprehensive ecological security assessment, risk early warning, and zoning management of lakes such as Poyang Lake.

The invention relates to the technical field of biological prevention and treatment, and discloses application of metarhizium anisopliae and beauveria bassiana in preparation of a microbial agent for preventing and treating clubroot of cruciferae, the microbial agent is a complex microbial agent, and the complex microbial agent comprises metarhizium anisopliae and beauveria bassiana. According to the invention, the clubroot of cruciferae is prevented and controlled by utilizing the bacteriostatic activity and composite synergistic effect of metarhizium anisopliae and beauveria bassiana. The fermentation liquor of the metarhizium anisopliae and the beauveria bassiana can directly act on the plasmodiophora brassicae spores, the inactivation rate of the plasmodiophora brassicae spores is remarkably increased, and disease infection is blocked from the source. The problems that disease-resistant varieties lose efficacy due to diversity of physiological races of germs, agricultural management measures have a limited effect on long-term survival spores, and chemical pesticides pollute the environment and induce drug resistance are solved; and the preparation in the technical scheme is environment-friendly, has no residue and is not easy to induce drug resistance of germs.

The utility model relates to the technical field of fire-fighting boots, in particular to a high-comfort fire-fighting protective boot for firefighters, which comprises a boot sole, a toe cap, a vamp, a heel and a boot leg which are integrally arranged, a waterproof sock is jointly attached to the inner surface layers of the toe cap, the vamp and the boot leg, and the boot leg comprises a leg body, a tibia protective layer, an ankle protective layer and an ankle joint bending layer. By means of the arrangement of the waterproof socks on the inner surface layers of the boot vamps and the boot legs, it is guaranteed that when a fireman works in the environments such as wading, the feet cannot be soaked by water, and the waterproof socks further have the functions of high breathability, chemical protection and blood transmission and viral pathogen resistance; meanwhile, the tibia protection layer, the ankle protection layer and the ankle joint bending layer are arranged, and the design fully considers the protection requirements of different parts of the feet of the firefighter when the firefighter executes a task, so that the firefighter can quickly respond in an emergency, and the timeliness and the accuracy of rescue actions are improved.

The present invention relates generally to a plant cell-surface immune receptor engineered to modulate an immune response in a plant, cell or seed, as well as nucleic acid molecules encoding the engineered receptor, and methods of use. In particular, the present invention relates to a plant cell-surface immune receptor into which a coiled-coil (CC) motif is integrated to enhance or modify the plant's immune response, with utility in reducing pathogen infection and improving pathogen resistance.

This invention belongs to the field of microbial technology and discloses a strain of *Citrobacter freundii* bacteriophage PRF337, its bacteriophage composition, and its applications. The *Citrobacter freundii* bacteriophage PRF337 was deposited on May 26, 2025, at the China General Microbiological Culture Collection Center (CGMCC), located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, with accession number CGMCC No. 46489. The bacteriophage PRF337 exhibits broad-spectrum bactericidal activity against *Citrobacter freundii*, capable of lysing *Citrobacter freundii* strains containing different virulence genes and from different sources. It also possesses certain temperature and pH stability and can be used as an active ingredient in pharmaceutical preparations, environmental disinfectants, and water purifiers. It can effectively control *Citrobacter freundii* infection in aquatic animals such as fish and shrimp in aquaculture environments and can also be used for the purification of pathogens in aquatic environments. It is safe to use and effectively avoids the problems of antibiotic residues and pathogen resistance caused by antibiotic use.

Synthetic Tombusviridae satellite RNA molecules and satellite particles containing the same are disclosed. Also disclosed are synthetic Tombusviridae satellite RNA molecules containing internal heterologous RNA virus (HRV) amplicons. Methods of using the Tombusviridae satellite RNA molecules and satellite particles containing the same to alter plant phenotype, improve stress resistance of plants, and improve pest and pathogen resistance of plants are also disclosed.

Synthetic turnip yellow mosaic virus satellite RNA molecules and satellite particles containing the same are disclosed. Synthetic turnip yellow mosaic virus satellite RNA molecules containing an internal heterologous RNA virus (HRV) amplicon are also disclosed. Also disclosed are methods of altering plant phenotypes, improving stress resistance in plants, and improving pest and pathogen resistance in plants using turnip yellow mosaic virus satellite RNA molecules and satellite particles containing the same.

The application belongs to the technical field of pesticides, and discloses a fungicidal composition and application thereof. The fungicidal composition comprises active ingredient A and active ingredient B. The active ingredient A is a compound of formula I. The active ingredient B is selected from any one of isoflucypram, fluoroimide and fluoroamide. The mass ratio of the active ingredient A to the active ingredient B is 1:35-32:1. The fungicidal composition has significant synergistic effect on various plant diseases in agriculture, is fast-acting, has long persistence, can delay the generation of pathogen resistance, and is suitable for comprehensive management of various plant diseases in agriculture.

The present application belongs to the technical field of fungicides, and particularly relates to a fungicidal composition for preventing and treating rust of figs. The fungicidal composition is used for preventing and treating rust of figs, and is composed of triforine and flusilazole or diclomezine. The present application compounding triforine and flusilazole or diclomezine in a certain mass ratio, and the compounding combination shows a synergistic effect on the rust pathogen of figs, Pucciniastrum ambrosiae, in a certain mass ratio range, and compared with single components, can improve the prevention and treatment effect on the rust of figs, delay the generation and development of the pathogen resistance, and reduce the resistance risk of the fungicidal composition. Secondly, the fungicidal composition can broaden the compounding combination of triforine, and provide support for fully developing the compounding medicament of triforine.

The present application relates to a kind of difficult culture pathogen resistance identification method and its application, belong to the field of agriculture and forestry science, step 1: the culture screening of toxic source plant, plant to be identified and indicator plant;Step 2: grafting transmission, the toxic source plant screened only with difficult culture pathogen, the plant to be identified without difficult culture pathogen and indicator plant are arranged in position, and transmission is carried out using grafting method;Step 3: observation and detection, according to the disease cycle of difficult culture pathogen, the disease phenotype of plant to be identified and indicator plant in step 2 is observed, and the colonization, propagation of difficult culture pathogen is detected by PCR method;Step 4: disease resistance and pathogen running speed evaluation.Effectively solve the problem that the identification result is inaccurate due to the low inoculation rate of difficult culture pathogen using transmission medium, the inconsistency of inoculation source pathogen and other reasons, the error is larger in resistance identification work, etc.

This invention provides the application of Evodia rutaecarpa root extract in the preparation of antifungal agents, belonging to the field of agricultural fungal control technology. The active ingredient of the Evodia rutaecarpa root extract is naturally derived and easily obtained; its unique chemical structure and novel mechanism of action effectively avoid the problem of pathogen resistance caused by the concentrated mechanisms of action of existing fungicides, filling the market gap for quinolone-based plant-derived pesticides. The Evodia rutaecarpa root extract exhibits a precise antifungal spectrum and significant inhibitory effect, showing obvious inhibitory activity against soil-borne and interplant-borne plant fungi that are serious threats in agricultural production, such as Phytophthora tobaccoii, Fusarium equisetifolium, Colletotrichum gloeosporioides, and Fusarium moniliforme.

Provided is a method for achieving high expression of a target substance in a plant. Also provided are a method of creating a plant with suppressed resistance to a pathogen, wherein the method comprises suppression or disruption of expression of a gene associated with a resistance mechanism in the plant, and a method of creating a plant with suppressed resistance to a pathogen wherein the method comprises overexpression of a gene related to degradation of salicylic acid (SA) in plants; as well as a transgenic plant or genome-edited plant obtained by the method; and a method for producing a target protein using the plant.

This invention belongs to the field of genetic engineering technology, specifically relating to the application of the AtHIR4 gene and / or its encoded protein in regulating plant pathogen resistance. The amino acid sequence of the protein encoded by the AtHIR4 gene described in this invention is shown in SEQ ID No. 1. This invention created transgenic Arabidopsis and rapeseed expressing hypersensitivity response-inducible protein 4 (AtHIR4). In the AtHIR4 transgenic Arabidopsis, the chitin-activated ROS burst and phosphorylation of MAPKs were significantly enhanced. Disease resistance test results showed that the AtHIR4 transgenic plants not only exhibited enhanced resistance to the necrotrophic pathogens *Sclerotinia sclerotiorum* and *Botrytis cinerea*, but also significantly increased resistance to the semi-vitrotrophic pathogen *Pseudomonas syringae*. The AtHIR4 transgenic rapeseed also showed significantly enhanced resistance to *Sclerotinia sclerotiorum* and *Botrytis cinerea*.

Synthetic endogenous ribonucleic acid virus satellite RNA molecules and satellite particles containing the same are disclosed. A synthetic endogenous ribonucleic acid virus satellite RNA molecule containing an endogenous heterologous TNA virus (HRV) amplicon is also disclosed. Also disclosed are methods of using endogenous ribonucleic acid virus satellite RNA molecules and satellite particles containing the same to alter plant phenotypes, improve stress resistance in plants, and improve pest and pathogen resistance in plants.

The invention relates to methods of identifying and characterizing a Cannabis spp. plant comprising a quantitative trait locus (QTL) or a causative polymorphism associated with pathogen resistance, and to Cannabis spp. plants having a pathogen resistance trait of interest comprising defined allelic states of polymorphisms defining the QTL. Also provided are plants with a pathogen resistance trait of interest identified by the methods described herein. The invention further relates to marker assisted selection and marker assisted breeding methods for obtaining plants having a pathogen resistance trait of interest, as well as to methods of producing Cannabis spp. plants with the pathogen resistance trait of interest and plants produced by these methods, based on the allelic state of the QTLs or the causative polymorphism.

The invention discloses a feed additive for improving pathogen resistance and intestinal injury of high-fat fed fishes and application of the feed additive, and belongs to the technical field of fish feed. The feed additive is indole-3-propionic acid, and the application of the feed additive is that IPA is added into a high-fat feed according to the addition amount of 20-160 mg / kg. Experiments find that IPA with different concentrations can significantly improve the aeromonas hydrophila infection resistance of tilapia fed with high fat, enhance the intestinal immune enzyme activity, improve the intestinal permeability, enhance the intestinal antioxidant ability and relieve intestinal inflammation. The IPA disclosed by the invention can be used as a novel feed additive, can effectively relieve the problems of pathogen resistance reduction and intestinal injury of high-fat fed fishes, and has a good application prospect.

By engineering genetic traits associated with photosynthesis in plants, transgenic plants with increased crop yield can be generated, which will ultimately lead to increased food production in the field. To obtain beneficial genetic traits for enhanced photosynthesis, accelerated evolution is applied under salt stress in a cyanobacteria species, Synechococcus elongatus PCC 7942, by conditionally suppressing its mismatch repair system. Through high-throughput screening for biomass accumulation and sucrose production, it is discovered that specific amino acid changes in the pre-Dl protein of Photosystem II (PSII), encoded by the psbA genes, can improve efficiency of photosynthesis under salt stress, as well as pathogen resistance. Next, the same amino acid changes were made in Arabadopsis and proved that photosynthetic efficiency (measured via growth rate) is also increased in this model vascular plant.

This invention relates to a compound microbial agent for promoting disease resistance and yield increase in chili peppers and its application. The strains in the compound microbial agent for promoting disease resistance and yield increase in chili peppers consist of Bacillus coagulans BC66, Lactobacillus plantarum LP194, and Bacillus polymyxa FangSG106. Studies have found that these three strains work synergistically to improve the resistance of chili peppers to root rot and increase chili pepper yield. This provides a new strategy for controlling chili pepper root rot and increasing chili pepper yield, solving the problems of poor efficacy and insignificant yield increase of commercially available products. As a microbial preparation, this agent has natural components, leaves no pesticide residue after use, and will not pollute the soil, water sources, or ecological environment. It also avoids the problem of pathogen resistance caused by chemical pesticides, conforming to the concepts of green agriculture and sustainable development, and is of great significance for ensuring the quality and safety of agricultural products.

This invention relates to the field of pesticides, specifically to a cyprodinil-chlorfluazol inhibitory and fungicidal composition. It addresses the problems of limited fungicidal activity in existing fungicides and the tendency for long-term single-use application to lead to pathogen resistance and reduced control efficacy. This fungicidal composition utilizes the different mechanisms of action of cyprodinil or cyprodinil acetate and chlorfluazol to exert its fungicidal effect. The combination of the two exhibits a significant synergistic effect, improving the control efficacy against pathogens and reducing the risk of pathogen resistance. The composition of this invention has good systemic and penetrating properties, maintaining efficacy within the crop for a long time, extending the residual effect, and reducing the frequency of application and costs.

Synthetic endornaviral satellite RNA molecules and satellite particles containing the same are disclosed. The synthetic endornaviral satellite RNA molecules can include coding and / or non-coding cargo sequences, and are heritable through generations of plants. Also disclosed are methods of using the endornaviral satellite RNA molecules and satellite particles containing the same to change plant phenotypes, improve plant stress resistance, and improve plant pest and pathogen resistance.

The present invention relates to novel tomato plants having improved resistance to lesion-forming pathogens. The present invention further relates to plant parts and seeds derived from said tomato plants, and to methods of making said tomato plants or increasing resistance to lesion-forming pathogens in a tomato plant. Further aspects of the invention relate to modified Pub21 nucleic acid and Pub21 protein sequences, and to the combination of modified Pub21 and Pub17 nucleic acid and Pub21 and Pub17 protein sequences, which are associated with such improved resistance to lesion-forming pathogens.

This invention belongs to the technical field of pesticide compound formulations, and discloses a fungicide and insecticide composition and its application. The composition includes effective active ingredients, namely compound I and compound II. Compound I is 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-2-methoxyethyl ester, and compound II is a fungicide or insecticide. The synergistic composition of this invention has the following advantages: 1) It has a synergistic effect, which can improve the control effect; 2) It broadens the fungicidal spectrum, as diseases often occur in combination in the field, and its effect on bacterial diseases is stronger; 3) The two active ingredients have different mechanisms of action, and their combined use can delay the development of pathogen resistance; 4) It reduces the amount of pesticide applied, the number of applications, and the cost of use.

The invention discloses a bactericidal composition for preventing and treating gray mold and application thereof, and belongs to the technical field of pesticides. The effective components of the bactericidal composition disclosed by the invention are the flurobixafen and the zhongshengmycin, wherein the mass ratio of the flurobixafen to the zhongshengmycin is (2-9): 1. The Zhongshengmycin and the chlorine fluorine bixafen are compounded for preventing and treating the gray mold, so that the pesticide dosage is reduced during use, the prevention and treatment cost is reduced, the generation of pathogenic bacterium resistance is delayed, and the pollution to the environment is reduced.