32 results about "Pathogen resistance" patented technology

Synthetic Southern Phaseoloviridae satellite RNA molecules and satellite particles containing the same are disclosed. Synthetic Southern Phaseoloviridae satellite RNA molecules containing an internal heterologous RNA virus (HRV) amplicon are also disclosed. Also disclosed are methods of using Southern Phaseoloviridae satellite RNA molecules and satellite particles containing the same to alter plant phenotypes, improve stress resistance in plants, and improve pest and pathogen resistance in plants.

Disclosed are synthetic Marivirus eye satellite RNA molecules and satellite particles containing the same. Also disclosed are synthetic mateur virus satellite RNA molecules containing an internal heterologous RNA virus (HRV) amplicon. Also disclosed are methods of altering plant phenotypes, improving stress resistance in plants, and improving pest and pathogen resistance in plants using the Marivirus eye satellite RNA molecules and satellite particles containing the same.

This invention relates to a method for risk assessment of multiple ecological factors in lakes based on DOM (Dissipative Oxygen Species), nutrients, and the coupling of functional bacteria and pathogen resistance. The invention aims to address the technical problems of current lake risk assessment methods, which primarily focus on evaluating single resistance risks, neglect the ecological buffering role of functional bacteria, and fail to reflect the coupled risks of multiple ecological factors in lakes. This invention obtains DOM parameters, nutrient parameters, functional bacteria indicators, pathogenic bacteria indicators, and drug resistance transmission factor indicators; calculates a comprehensive risk value R based on the environmental stress index E, ecological buffering index B, transmission hazard index H, and DOM-mediated transmission triggering coefficient K, and performs risk classification and spatial zoning assessment. This invention incorporates DOM activity, nutrient imbalance, the ecological buffering capacity of functional bacteria, and the drug resistance transmission potential of pathogenic bacteria into a unified evaluation framework, applicable to comprehensive ecological security assessment, risk early warning, and zoning management of lakes such as Poyang Lake.

The utility model relates to the technical field of fire-fighting boots, in particular to a high-comfort fire-fighting protective boot for firefighters, which comprises a boot sole, a toe cap, a vamp, a heel and a boot leg which are integrally arranged, a waterproof sock is jointly attached to the inner surface layers of the toe cap, the vamp and the boot leg, and the boot leg comprises a leg body, a tibia protective layer, an ankle protective layer and an ankle joint bending layer. By means of the arrangement of the waterproof socks on the inner surface layers of the boot vamps and the boot legs, it is guaranteed that when a fireman works in the environments such as wading, the feet cannot be soaked by water, and the waterproof socks further have the functions of high breathability, chemical protection and blood transmission and viral pathogen resistance; meanwhile, the tibia protection layer, the ankle protection layer and the ankle joint bending layer are arranged, and the design fully considers the protection requirements of different parts of the feet of the firefighter when the firefighter executes a task, so that the firefighter can quickly respond in an emergency, and the timeliness and the accuracy of rescue actions are improved.

The present invention relates generally to a plant cell-surface immune receptor engineered to modulate an immune response in a plant, cell or seed, as well as nucleic acid molecules encoding the engineered receptor, and methods of use. In particular, the present invention relates to a plant cell-surface immune receptor into which a coiled-coil (CC) motif is integrated to enhance or modify the plant's immune response, with utility in reducing pathogen infection and improving pathogen resistance.

This invention belongs to the field of microbial technology and discloses a strain of *Citrobacter freundii* bacteriophage PRF337, its bacteriophage composition, and its applications. The *Citrobacter freundii* bacteriophage PRF337 was deposited on May 26, 2025, at the China General Microbiological Culture Collection Center (CGMCC), located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, with accession number CGMCC No. 46489. The bacteriophage PRF337 exhibits broad-spectrum bactericidal activity against *Citrobacter freundii*, capable of lysing *Citrobacter freundii* strains containing different virulence genes and from different sources. It also possesses certain temperature and pH stability and can be used as an active ingredient in pharmaceutical preparations, environmental disinfectants, and water purifiers. It can effectively control *Citrobacter freundii* infection in aquatic animals such as fish and shrimp in aquaculture environments and can also be used for the purification of pathogens in aquatic environments. It is safe to use and effectively avoids the problems of antibiotic residues and pathogen resistance caused by antibiotic use.

Synthetic Tombusviridae satellite RNA molecules and satellite particles containing the same are disclosed. Also disclosed are synthetic Tombusviridae satellite RNA molecules containing internal heterologous RNA virus (HRV) amplicons. Methods of using the Tombusviridae satellite RNA molecules and satellite particles containing the same to alter plant phenotype, improve stress resistance of plants, and improve pest and pathogen resistance of plants are also disclosed.

Synthetic turnip yellow mosaic virus satellite RNA molecules and satellite particles containing the same are disclosed. Synthetic turnip yellow mosaic virus satellite RNA molecules containing an internal heterologous RNA virus (HRV) amplicon are also disclosed. Also disclosed are methods of altering plant phenotypes, improving stress resistance in plants, and improving pest and pathogen resistance in plants using turnip yellow mosaic virus satellite RNA molecules and satellite particles containing the same.

The application belongs to the technical field of pesticides, and discloses a fungicidal composition and application thereof. The fungicidal composition comprises active ingredient A and active ingredient B. The active ingredient A is a compound of formula I. The active ingredient B is selected from any one of isoflucypram, fluoroimide and fluoroamide. The mass ratio of the active ingredient A to the active ingredient B is 1:35-32:1. The fungicidal composition has significant synergistic effect on various plant diseases in agriculture, is fast-acting, has long persistence, can delay the generation of pathogen resistance, and is suitable for comprehensive management of various plant diseases in agriculture.

The present application belongs to the technical field of fungicides, and particularly relates to a fungicidal composition for preventing and treating rust of figs. The fungicidal composition is used for preventing and treating rust of figs, and is composed of triforine and flusilazole or diclomezine. The present application compounding triforine and flusilazole or diclomezine in a certain mass ratio, and the compounding combination shows a synergistic effect on the rust pathogen of figs, Pucciniastrum ambrosiae, in a certain mass ratio range, and compared with single components, can improve the prevention and treatment effect on the rust of figs, delay the generation and development of the pathogen resistance, and reduce the resistance risk of the fungicidal composition. Secondly, the fungicidal composition can broaden the compounding combination of triforine, and provide support for fully developing the compounding medicament of triforine.

The present application relates to a kind of difficult culture pathogen resistance identification method and its application, belong to the field of agriculture and forestry science, step 1: the culture screening of toxic source plant, plant to be identified and indicator plant;Step 2: grafting transmission, the toxic source plant screened only with difficult culture pathogen, the plant to be identified without difficult culture pathogen and indicator plant are arranged in position, and transmission is carried out using grafting method;Step 3: observation and detection, according to the disease cycle of difficult culture pathogen, the disease phenotype of plant to be identified and indicator plant in step 2 is observed, and the colonization, propagation of difficult culture pathogen is detected by PCR method;Step 4: disease resistance and pathogen running speed evaluation.Effectively solve the problem that the identification result is inaccurate due to the low inoculation rate of difficult culture pathogen using transmission medium, the inconsistency of inoculation source pathogen and other reasons, the error is larger in resistance identification work, etc.

This invention provides the application of Evodia rutaecarpa root extract in the preparation of antifungal agents, belonging to the field of agricultural fungal control technology. The active ingredient of the Evodia rutaecarpa root extract is naturally derived and easily obtained; its unique chemical structure and novel mechanism of action effectively avoid the problem of pathogen resistance caused by the concentrated mechanisms of action of existing fungicides, filling the market gap for quinolone-based plant-derived pesticides. The Evodia rutaecarpa root extract exhibits a precise antifungal spectrum and significant inhibitory effect, showing obvious inhibitory activity against soil-borne and interplant-borne plant fungi that are serious threats in agricultural production, such as Phytophthora tobaccoii, Fusarium equisetifolium, Colletotrichum gloeosporioides, and Fusarium moniliforme.

Provided is a method for achieving high expression of a target substance in a plant. Also provided are a method of creating a plant with suppressed resistance to a pathogen, wherein the method comprises suppression or disruption of expression of a gene associated with a resistance mechanism in the plant, and a method of creating a plant with suppressed resistance to a pathogen wherein the method comprises overexpression of a gene related to degradation of salicylic acid (SA) in plants; as well as a transgenic plant or genome-edited plant obtained by the method; and a method for producing a target protein using the plant.

Synthetic endogenous ribonucleic acid virus satellite RNA molecules and satellite particles containing the same are disclosed. A synthetic endogenous ribonucleic acid virus satellite RNA molecule containing an endogenous heterologous TNA virus (HRV) amplicon is also disclosed. Also disclosed are methods of using endogenous ribonucleic acid virus satellite RNA molecules and satellite particles containing the same to alter plant phenotypes, improve stress resistance in plants, and improve pest and pathogen resistance in plants.

The invention discloses a feed additive for improving pathogen resistance and intestinal injury of high-fat fed fishes and application of the feed additive, and belongs to the technical field of fish feed. The feed additive is indole-3-propionic acid, and the application of the feed additive is that IPA is added into a high-fat feed according to the addition amount of 20-160 mg / kg. Experiments find that IPA with different concentrations can significantly improve the aeromonas hydrophila infection resistance of tilapia fed with high fat, enhance the intestinal immune enzyme activity, improve the intestinal permeability, enhance the intestinal antioxidant ability and relieve intestinal inflammation. The IPA disclosed by the invention can be used as a novel feed additive, can effectively relieve the problems of pathogen resistance reduction and intestinal injury of high-fat fed fishes, and has a good application prospect.

This invention relates to a compound microbial agent for promoting disease resistance and yield increase in chili peppers and its application. The strains in the compound microbial agent for promoting disease resistance and yield increase in chili peppers consist of Bacillus coagulans BC66, Lactobacillus plantarum LP194, and Bacillus polymyxa FangSG106. Studies have found that these three strains work synergistically to improve the resistance of chili peppers to root rot and increase chili pepper yield. This provides a new strategy for controlling chili pepper root rot and increasing chili pepper yield, solving the problems of poor efficacy and insignificant yield increase of commercially available products. As a microbial preparation, this agent has natural components, leaves no pesticide residue after use, and will not pollute the soil, water sources, or ecological environment. It also avoids the problem of pathogen resistance caused by chemical pesticides, conforming to the concepts of green agriculture and sustainable development, and is of great significance for ensuring the quality and safety of agricultural products.

This invention relates to the field of pesticides, specifically to a cyprodinil-chlorfluazol inhibitory and fungicidal composition. It addresses the problems of limited fungicidal activity in existing fungicides and the tendency for long-term single-use application to lead to pathogen resistance and reduced control efficacy. This fungicidal composition utilizes the different mechanisms of action of cyprodinil or cyprodinil acetate and chlorfluazol to exert its fungicidal effect. The combination of the two exhibits a significant synergistic effect, improving the control efficacy against pathogens and reducing the risk of pathogen resistance. The composition of this invention has good systemic and penetrating properties, maintaining efficacy within the crop for a long time, extending the residual effect, and reducing the frequency of application and costs.

Synthetic endornaviral satellite RNA molecules and satellite particles containing the same are disclosed. The synthetic endornaviral satellite RNA molecules can include coding and / or non-coding cargo sequences, and are heritable through generations of plants. Also disclosed are methods of using the endornaviral satellite RNA molecules and satellite particles containing the same to change plant phenotypes, improve plant stress resistance, and improve plant pest and pathogen resistance.

This invention belongs to the technical field of pesticide compound formulations, and discloses a fungicide and insecticide composition and its application. The composition includes effective active ingredients, namely compound I and compound II. Compound I is 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-2-methoxyethyl ester, and compound II is a fungicide or insecticide. The synergistic composition of this invention has the following advantages: 1) It has a synergistic effect, which can improve the control effect; 2) It broadens the fungicidal spectrum, as diseases often occur in combination in the field, and its effect on bacterial diseases is stronger; 3) The two active ingredients have different mechanisms of action, and their combined use can delay the development of pathogen resistance; 4) It reduces the amount of pesticide applied, the number of applications, and the cost of use.

The invention discloses a bactericidal composition for preventing and treating gray mold and application thereof, and belongs to the technical field of pesticides. The effective components of the bactericidal composition disclosed by the invention are the flurobixafen and the zhongshengmycin, wherein the mass ratio of the flurobixafen to the zhongshengmycin is (2-9): 1. The Zhongshengmycin and the chlorine fluorine bixafen are compounded for preventing and treating the gray mold, so that the pesticide dosage is reduced during use, the prevention and treatment cost is reduced, the generation of pathogenic bacterium resistance is delayed, and the pollution to the environment is reduced.

Synthetic split viral satellite RNA molecules and satellite particles containing the same are disclosed. Also disclosed are synthetic split viral satellite RNA molecules containing an internal heterologous TNA virus (HRV) amplicon. Also disclosed are methods of using the split viral satellite RNA molecules and satellite particles containing the same to alter plant phenotypes, improve stress resistance in plants, and improve pest and pathogen resistance in plants.

Disclosed herein are compositions and methods for improving or enhancing pathogen resistance in legume plants. Compositions comprising polypeptides encoded by the CcRpp2-R1 and CcRpp2-R3 polynucleotides disclosed herein are useful in improving resistance in legumes to Asian Soybean Rust (ASR). Methods of using CcRpp2-R1 and CcRpp2-R3 genes to make transgenic ASR-resistant legume plants are also disclosed.

The present application belongs to the technical field of pesticides, and particularly relates to a fungicidal composition for preventing and treating oil olive root rot. The effective components of the fungicidal composition are formed by binary compounding of fluoximide and berberine or natamycin. When fluoximide and berberine or natamycin are binary compounded, the synergistic coefficient of the fungicidal composition to phytophthora cinnamomi is greater than 1.5, that is, the fungicidal composition exhibits a certain synergistic effect. In particular, when the mass ratio of fluoximide to natamycin is 8:1, the SR value of the fungicidal composition reaches 11.2394, and the synergistic effect is the most significant. Therefore, the fungicidal composition can help to improve the prevention and treatment effect on oil olive root rot, and can be used for developing a high-efficiency fungicide for preventing and treating oil olive root rot. In addition, the fungicidal composition is formed by binary compounding of two effective components, can delay the development of pathogen resistance, and reduce the risk of drug resistance.

Synthetic mixed viral satellite RNA molecules and satellite particles containing the same are disclosed. Synthetic mixed viral satellite RNA molecules containing an internal heterologous RNA virus (HRV) amplicon are also disclosed. Also disclosed are methods of altering plant phenotypes, improving stress resistance in plants, and improving pest and pathogen resistance in plants using the mixed virus satellite RNA molecules and satellite particles containing the same.

The present invention comprises a consortium of Lactobacillus crispatus with pathogen resistance and anti-steatosis functions for nutraceutical and therapeutic uses and method thereof. The present invention comprises an indigenous microbiota that inhibit the growth of pathogenic bacteria, including Escherichia coli, Klebsiella pneumoniae, Enterobacter hormaechei, Staphylococcus aureus, Gardnerella vaginalis and reduce the accumulation of visceral and hepatic fat.

Disclosed herein are compositions and methods for improving or enhancing pathogen resistance in legume plants. Compositions comprising polypeptides encoded by the chimeric nucleotide-biding site leucine-rich repeat (NLR) polynucleotides disclosed herein are useful in improving resistance in legumes to Asian soybean rust (ASR). Methods of using the chimeric NLR polynucleotides disclosed herein to make transgenic ASR-resistant legume plants are also disclosed.

This invention discloses a streptomycin resistance gene, its encoded protein, and its applications, belonging to the field of plant pathology technology. This invention discovers a novel streptomycin resistance gene derived from *Tomato Canker*. aph(3) This gene is located on a newly discovered plasmid pCM3 of *Tomato Canker*, encoding a protein APH(3) belonging to the aminoglycoside antibiotic phosphotransferase family. This invention verified the function of this gene through gene knockout, functional complementation, and heterologous expression experiments. Simultaneously, mass spectrometry analysis demonstrated that APH(3) catalyzes the phosphorylation of streptomycin molecules, generating streptomycin monophosphate, thereby eliminating its inhibitory activity against bacteria. Strains carrying this gene exhibit significant resistance to streptomycin. This invention relates to a streptomycin resistance gene. aph(3) It can be widely used in the study of pathogen resistance mechanisms, screening of resistant strains, and selection of molecular markers, and has important scientific research and application value.

The invention belongs to the technical field of biological prevention and control, and provides application of 2-(2-chlorophenyl)-1, 2, 4-oxadiazole in inhibition of tea tree leaf spot bacteria, and the 2-(2-chlorophenyl)-1, 2, 4-oxadiazole synergistically exerts an antibacterial effect through multiple mechanisms of destroying plasma membranes and cell wall structures of pathogenic bacteria, blocking an ATP synthesis pathway, interfering glucose metabolism and the like. The problems of aggravated drug resistance of pathogenic bacteria caused by single action target of the existing chemical bactericide and environmental pollution caused by high-toxicity pesticides are solved; as a derivative of a plant source natural product, namely gallic acid thiadiazole, dichlorxazole can completely inhibit mycelial growth of tea tree phyllosticta under the concentration of 15 mg / L, has the characteristics of high efficiency, low toxicity and environment friendliness, and has an antibacterial effect on various plant pathogenic bacteria such as tea anthracnose bacteria, tea physalospora, botrytis cinerea and sclerotinia sclerotiorum; the composition is suitable for green disease prevention and control of crops such as tea, rape and tomato.

This invention provides the application of the PeBL1 gene and its protein in the control of tomato diseases. Specifically, this invention provides the application of the PeBL1 protein in improving the resistance of tomatoes to pathogens and / or in the preparation of products that enhance the resistance of tomatoes to pathogens, wherein the pathogens include Fusarium oxysporum tomato neck and root rot specific type (FORL) and tomato brown fruit wrinkle virus (ToBRFV), and the amino acid sequence of the PeBL1 protein is shown in SEQ ID NO:1. The PeBL1 protein can enhance the resistance of tomatoes to Fusarium oxysporum tomato neck and root rot specific type, significantly reduce the accumulation of Tomato brown fruit wrinkle virus on tomatoes, and reduce the impact of the virus on the growth of tomato plants.

Root-knot nematodes (RKN) are pathogens affecting soybean production worldwide. Rmi1 (Resistance to M. incognita 1) is an additive gene for M. incognita resistance identified in soybean cv. Forrest, which resides in a major QTL on Chromosome 10. It has been established that Rmi1 is associated with multiple polymorphisms in the promoter and sequences of genes encoding β-1,4-endoglucancase (EG) and pectin methylesterase (PME1), both of which exhibit higher expression in susceptible than in Rmi1 resistant plants. EG expression is correlated with RKN feeding cell formation, indicating EG functions as a susceptibility factor for soybean resistance to M. incognita. Plants, including genetically modified and transgenic plants, cells and seeds thereof that lack expression or functional gene products of EG and / or PME1 are provided. Compositions and methods for reducing or removing EG and / or PME1 expression in plants are also described.