10 results about "Pathogen resistance" patented technology

This invention relates to a method for risk assessment of multiple ecological factors in lakes based on DOM (Dissipative Oxygen Species), nutrients, and the coupling of functional bacteria and pathogen resistance. The invention aims to address the technical problems of current lake risk assessment methods, which primarily focus on evaluating single resistance risks, neglect the ecological buffering role of functional bacteria, and fail to reflect the coupled risks of multiple ecological factors in lakes. This invention obtains DOM parameters, nutrient parameters, functional bacteria indicators, pathogenic bacteria indicators, and drug resistance transmission factor indicators; calculates a comprehensive risk value R based on the environmental stress index E, ecological buffering index B, transmission hazard index H, and DOM-mediated transmission triggering coefficient K, and performs risk classification and spatial zoning assessment. This invention incorporates DOM activity, nutrient imbalance, the ecological buffering capacity of functional bacteria, and the drug resistance transmission potential of pathogenic bacteria into a unified evaluation framework, applicable to comprehensive ecological security assessment, risk early warning, and zoning management of lakes such as Poyang Lake.

The present invention relates generally to a plant cell-surface immune receptor engineered to modulate an immune response in a plant, cell or seed, as well as nucleic acid molecules encoding the engineered receptor, and methods of use. In particular, the present invention relates to a plant cell-surface immune receptor into which a coiled-coil (CC) motif is integrated to enhance or modify the plant's immune response, with utility in reducing pathogen infection and improving pathogen resistance.

This invention belongs to the field of microbial technology and discloses a strain of *Citrobacter freundii* bacteriophage PRF337, its bacteriophage composition, and its applications. The *Citrobacter freundii* bacteriophage PRF337 was deposited on May 26, 2025, at the China General Microbiological Culture Collection Center (CGMCC), located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, with accession number CGMCC No. 46489. The bacteriophage PRF337 exhibits broad-spectrum bactericidal activity against *Citrobacter freundii*, capable of lysing *Citrobacter freundii* strains containing different virulence genes and from different sources. It also possesses certain temperature and pH stability and can be used as an active ingredient in pharmaceutical preparations, environmental disinfectants, and water purifiers. It can effectively control *Citrobacter freundii* infection in aquatic animals such as fish and shrimp in aquaculture environments and can also be used for the purification of pathogens in aquatic environments. It is safe to use and effectively avoids the problems of antibiotic residues and pathogen resistance caused by antibiotic use.

Synthetic Tombusviridae satellite RNA molecules and satellite particles containing the same are disclosed. Also disclosed are synthetic Tombusviridae satellite RNA molecules containing internal heterologous RNA virus (HRV) amplicons. Methods of using the Tombusviridae satellite RNA molecules and satellite particles containing the same to alter plant phenotype, improve stress resistance of plants, and improve pest and pathogen resistance of plants are also disclosed.

This invention provides the application of Evodia rutaecarpa root extract in the preparation of antifungal agents, belonging to the field of agricultural fungal control technology. The active ingredient of the Evodia rutaecarpa root extract is naturally derived and easily obtained; its unique chemical structure and novel mechanism of action effectively avoid the problem of pathogen resistance caused by the concentrated mechanisms of action of existing fungicides, filling the market gap for quinolone-based plant-derived pesticides. The Evodia rutaecarpa root extract exhibits a precise antifungal spectrum and significant inhibitory effect, showing obvious inhibitory activity against soil-borne and interplant-borne plant fungi that are serious threats in agricultural production, such as Phytophthora tobaccoii, Fusarium equisetifolium, Colletotrichum gloeosporioides, and Fusarium moniliforme.

This invention relates to a compound microbial agent for promoting disease resistance and yield increase in chili peppers and its application. The strains in the compound microbial agent for promoting disease resistance and yield increase in chili peppers consist of Bacillus coagulans BC66, Lactobacillus plantarum LP194, and Bacillus polymyxa FangSG106. Studies have found that these three strains work synergistically to improve the resistance of chili peppers to root rot and increase chili pepper yield. This provides a new strategy for controlling chili pepper root rot and increasing chili pepper yield, solving the problems of poor efficacy and insignificant yield increase of commercially available products. As a microbial preparation, this agent has natural components, leaves no pesticide residue after use, and will not pollute the soil, water sources, or ecological environment. It also avoids the problem of pathogen resistance caused by chemical pesticides, conforming to the concepts of green agriculture and sustainable development, and is of great significance for ensuring the quality and safety of agricultural products.

This invention relates to the field of pesticides, specifically to a cyprodinil-chlorfluazol inhibitory and fungicidal composition. It addresses the problems of limited fungicidal activity in existing fungicides and the tendency for long-term single-use application to lead to pathogen resistance and reduced control efficacy. This fungicidal composition utilizes the different mechanisms of action of cyprodinil or cyprodinil acetate and chlorfluazol to exert its fungicidal effect. The combination of the two exhibits a significant synergistic effect, improving the control efficacy against pathogens and reducing the risk of pathogen resistance. The composition of this invention has good systemic and penetrating properties, maintaining efficacy within the crop for a long time, extending the residual effect, and reducing the frequency of application and costs.

Synthetic endornaviral satellite RNA molecules and satellite particles containing the same are disclosed. The synthetic endornaviral satellite RNA molecules can include coding and / or non-coding cargo sequences, and are heritable through generations of plants. Also disclosed are methods of using the endornaviral satellite RNA molecules and satellite particles containing the same to change plant phenotypes, improve plant stress resistance, and improve plant pest and pathogen resistance.

Disclosed herein are compositions and methods for improving or enhancing pathogen resistance in legume plants. Compositions comprising polypeptides encoded by the chimeric nucleotide-biding site leucine-rich repeat (NLR) polynucleotides disclosed herein are useful in improving resistance in legumes to Asian soybean rust (ASR). Methods of using the chimeric NLR polynucleotides disclosed herein to make transgenic ASR-resistant legume plants are also disclosed.

This invention provides a machine learning-based system for predicting the trend of drug resistance in pet pathogens, relating to the field of digital data processing technology. It includes: a multi-source heterogeneous data integration module for real-time acquisition and integration of relevant parameters of pet bacterial strains, and for performing accuracy verification; a data standardization preprocessing module for generating a standardized pathogen resistance dataset; a high-dimensional feature representation learning module for constructing a latent semantic association model; a spatiotemporal evolution modeling module for generating evolutionary features; a drug resistance trend prediction module for outputting predicted resistance rates of specific pathogens to specific antimicrobial drugs; and a decision support and early warning feedback module for automatically generating clinical medication guidance and drug resistance risk warning reports. This invention solves the problems of low data processing efficiency, delayed monitoring results, insufficient feature extraction capabilities, and difficulty in capturing long-term nonlinear evolutionary trends in existing technologies.