1329 results about "Fungal disease" patented technology

The invention relates to plant endogenous bacillus velezensis which is capable of preventing and treating plant diseases and insects and has functions of growth promotion and drought resistance, and application thereof. The preservation number of the Bacillus velezensis E6 provided by the invention in the China General Microbiological Culture Collection Center is CGMCC No. 9665. The strain is separated from a plant root, is rapid to grow, can be rapidly and greatly colonized at plant roots and has ecological niche advantages; the strain E6 not only has an efficient prevention and treatment function on plant soil-borne fungal diseases and is capable of promoting growth of plant root systems and improving drought resistance of plants, but also is capable of damaging formation of pathogenic bacterium bacterial biofilms, is free of drug resistance of bacteria, has relatively good advantages when being compared with other fungicides, is simple in nutrition requirement and low in productioncost, and has good application prospects.

The invention discloses a preparation method and application of rhamnolipid. In the method, the rhamnolipid is produced by using waste grease as carbon source, and utilizing the fermentation of pseudomonas aeruginosa; and with the combination of the defoaming effect of ethanol, the yield of the rhamnolipid can reach 35 to 50 g/L and the cost is about 25 to 40 percent lower than that of the conventional method. When the solution containing 20 to 500 mg/L of rhamnolipid is used for processing plant disease fungus, the ratio of inhibiting disease fungal mycelium growth and spore germination can reach 40 to 90 percent and the plant fungal diseases can be effectively inhibited; the solution containing 20 to 500 mg/L of rhamnolipid has an obvious effect of killing cockroaches and aphids; and in addition, when the rhamnolipid is used as an aid of pesticide, fertilizer and feed and a dehydrating agent of oil-contained sludge by replacing a chemical surface active agent, the effect is obvious.

The invention provides a fungicide composition containing an active component A and an active component B, and application thereof in preventing and controlling various agricultural fungal diseases. The active component A in the composition is one of two methoxyl acrylic ester compounds; and as shown above, the active component B of the compound A1 and the compound A2 is one of the following fungicide varieties: thiocarbamate compounds or salt thereof, aliphatic compounds or salt thereof, carbamate compounds or salt thereof, oxazole compounds or salt thereof, thiazole compounds or salt thereof, amide compounds or salt thereof, organophosphorus compounds or salt thereof, imidazole compounds or salt thereof, antibiotic compounds or salt thereof, pyridine compounds or salt thereof and triazole compounds or salt thereof.

A multivalent fungal vaccine comprising one or more heat-inactivated fungal antigens, wherein at least one fungal antigen is effective in producing an immune response in a host when said vaccine is administered orally at a dose that is sufficient for preventing or treating the fungal disease in said host. Also described are methods for making and using an orally available anti-fungal vaccine.

The present invention relates to compounds of formula (I):

or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein U, J, V, X, R^2a, R^2b, R^2c, R⁵ and t are as described herein. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. These compounds are useful for promoting cognitive function and enhancing learning and memory formation. In addition, these compounds are useful for treating, alleviating, and/or preventing various conditions, including for example, neurological disorders, memory and cognitive function disorders/impairments, extinction learning disorders, fungal diseases and infections, inflammatory diseases, hematological diseases, and neoplastic diseases in humans and animals.

The present invention relates to the field of plant breeding. More specifically, the present invention includes a method of using haploid plants for genetic mapping of traits such as disease resistance. Further, the invention includes a method for breeding corn plants containing quantitative trait loci (QTL) that are associated with resistance to Gray Leaf Spot (GLS), a fungal disease associated with Cercospora spp. The invention further includes a method for breeding corn plants containing QTL that are associated with Goss' Wilt, a bacterial disease associated with Clavibacter michiganense spp.

The invention provides bacillus amyloliquefaciens SZ-60 which is characterized in that the collection number is CGMCC No.8277. The bacterial colony formed by the strain on a beef-extract peptone (NB) medium by virtue of single-cell reproduction is irregular with oyster white color, slight upheaval at the center and wet and semitransparent surface; the microscopy is of a rod shape, and the size is (0.3-0.4)*(3.2-3.3)microns; with flagella, G- and spores, the strain can grow on the beef-extract peptone (NB) medium containing 2-5% of NaCl; the formula of the beef-extract peptone (NB) medium contains 3.0g of beef extract, 10.0g of peptone, 5.0g of NaCl, 17g of agar and 1,000ml of water, and the pH is 6.8-7.2. The bacillus amyloliquefaciens realizes a remarkable antagonistic action on the main pathogenic bacteria causing ginseng root rot, epidemic diseases, sclerotinia sclerotiorum, cylindrocarpon destructans, black spot and damping off. The invention also provides an application of the bacillus amyloliquefaciens SZ-60 in preventing plant fungal diseases, or application in preparing a microbial preparation for preventing plant fungal diseases.

The invention discloses a tomato SlML1 gene and application, and belongs to the field of biological techniques. The cDNA sequence and the encoding amino acid sequence of the gene are as shown in SEQIDNO.1 and SEQIDNO.2. The transgenosis experiment shows that the gene not only has the functions of improving the quality and increasing the yield of tomatoes, but also has the properties of improving the drought resistance, the fungal disease resistance, bacterial disease resistance and TMV and insect resistance of tomatoes, and moreover the shelf life of tomatoes can be prolonged. Therefore, SlML1 can be used as a target gene introduction plant for improving the quality and the resistance and increasing the yield of plants and has good application prospect in breeding, quality improvement and resistance study on tomatoes.

The invention discloses a Paenibacillus kribbensis, and a preparation method and an application thereof. The Paenibacillus kribbensis has a bacterial code name of TRCC82001, is preserved in China General Microbiological Culture Collection Center, and has a preservation number of CGMCCNo.7996. The above bacterial strain has the advantages of good production property, good metabolite antimicrobial effect, and strong activity against rice blast and sheath blight, and a solution obtained after diluting a broth subjected to antibiotic treatment to 100 times has an inhibition effect of above 80% on the rice blast and sheath blight. The bacterial strain and its metabolites have a broad antimicrobial spectrum, can be used for preparing biocontrol preparations for the broad spectrum activity inhibition of pathogenic fungi to control the fungal diseases of plants.

The invention discloses bacillus subtilis and propiconazole compound wettable sterilizing powder. The finished medicament comprises active ingredients, assistants and a filler assistant, and is characterized in that: the active ingredients account for 10 to 85 percent of the total weight of the finished medicament and consist of the bacillus subtilis and the propiconazole; and the bacillus subtilis accounts for 10 to 90 percent of the weight of the active ingredients. To be used, the finished medicament is diluted and sprayed onto fruit trees to prevent and control fungal diseases of the fruit trees. The finished medicament has the advantages that: due to the use of the bacillus subtilis and the propiconazole which are mixed in a certain ratio, the synergy of microorganisms and chemical agents can be fully played, so as to complement mutual advantages, enlarge prevention and control range, reduce dosage of the chemical agents, reduce medicinal administration cost, improve prevention and control effect, improve the ecological environment in fruit gardens and reduce the residues of chemical agents in fruits.

Disclosed is a pyrazole amide compound as represented by general formula I, wherein, R1 is selected from hydrogen, C1-C4 alkyl, C2-C6 alkenyl, and C1-C6 alkyl; and R2 and R3 can be the same or different, and are respectively and independently selected from the C1-C6 alkyl. The general formula I compound has an excellent bactericidal activity, and can be used to prevent and control fungal diseases.

The invention relates to a separation and purification method of endophytic fungi from ginkgo biloba. The separation and purification method comprises the following operation steps of: (1) preparing ginkgo biloba tissues: collecting roots, stems and leaves of the ginkgo biloba and preserving under the condition that the temperature is 4 DEG C; (2) performing surface disinfection and sterile detection on the ginkgo biloba tissues; and (3) performing separation culture on the endophytic fungi from the ginkgo biloba tissues. The endophytic fungi from the ginkgo biloba, described by the invention, is named as Fusariumsolani T-7 and currently collected in China General Microbiological Culture Collection Center designated by State Intellectual Property Office, the collection data is July 20, 2011, and the collection number is CGMCC No. 5089. The endophytic fungi from the ginkgo biloba, disclosed by the invention has the microbiology position of the Fusariumsolani T-7 with broad-spectrum antimicrobial activity, and the strain is simultaneously found to have an obvious effect of inhibiting the growth of mycelia against pathogenic fungi of six tested plants. According to the separation and purification method disclosed by the invention, resources of the plant endophytic fungi are utilized to get a novel agricultural antibiotic type natural component for resisting diseases caused by the plant pathogenic fungi.

The invention relates to application and preparation of bacillus amyloliquefaciens subsp. plantarum and a bacterial agent thereof. An XH-9 bacterial strain is identified as bacillus amyloliquefaciens subsp. plantarum according to mycelial morphology, colony characteristics, physiological and biochemical indexes and 16S rDNA sequence analysis and is preserved in the China General Microbiological Culture Collection Center, and a preservation number is CGMCC NO.13151. The strain is high in antagonistic effect on pathogenic fungi such as fusarium oxysporum, bipolaris sorokiniana, fusarium pseudograminearum, colletotrichum gloeosporioides, botryosphaeria dothidea and alternaria alternata and is capable of generating heteroauxin and 1-aminocyclopropanecarboxylic acid (ACC) deaminase to stimulate plant growth and capable of degrading celluloses and can be stably colonized at rhizospheres of crops such as wheat, corn, peppers and the like. The bacterial agent prepared from the bacterial strain can be applied to prevention and treatment of root rot diseases or other soil-borne fungal diseases of crops such as wheat, corn, peppers and the like and has dual functions of disease prevention and growth promotion. The bacterial agent is simple in preparation process, short in fermentation period, low in cost and beneficial to industrial production and transport.

The invention discloses a preparation method of microbial pesticide for controlling vegetable fungal diseases, belonging to the microbial technical field, which utilizes a streptomyces diastatochromogenes D isolated and screened from a soil sample to prepare various formulation pesticides with the steps of the activation cultivation of strain, fermentation cultivation, leavening extraction and distribution of pesticide auxiliary material to the purified active composite, wherein the soil sample is acquired from Lin' an Tianmu mountain in Hangzhou, Zhejiang. The preparation method of microbial pesticide for controlling vegetable fungal diseases is safe and can be used for controlling cucumber fusarium wilt, tomato gray mold, and other vegetable fungal diseases; and the controlling effect is a little better than normal chemical agents.

The invention discloses a compound microbial fertilizer for antagonism of soil-borne fungal diseases, and a preparation method and an application thereof; the fertilizer takes humic acid as a compound carrier, includes bacillus amyloliquefaciens HFJ-7 with the bacteria content of 1.8*10<8>-2.1*10<8> CFU/g, and also includes bacillus megatherium B3. The bacillus amyloliquefaciens HFJ-7 in the compound microbial fertilizer has the preservation number of CGMCC No.10011. The bacillus amyloliquefaciens HFJ-7 strain can be antagonistic to rhizoctonia solani, fusarium oxysporum, root rot pathogen, cucumber fusarium wilt pathogen, phytophthora capsici leon pathogen and other soil-borne disease pathogenic fungi. After the bacillus amyloliquefaciens HFJ-7 is compounded with the bacillus megatherium B3, the resistance to rhizoctonia solani and pepper root rot pathogen can be significantly improved, a disease state index of pepper seedling root rot disease can be significantly reduced, and the occurrence and spreading of pepper root rot can be effectively prevented and controlled.

The invention discloses a gliocladium spp. strain for suppressing botrytis cinerea pers and relates to the gliocladium spp. strain. The invention provides a new strain of gliocladium spp., which can be used for suppressing the botrytis cinerea pers and have the effect of suppressing a plurality of other fungal diseases, thereby laying a material foundation for biological control of the botrytis cinerea pers and culture of new species for anti-botrytis cinerea pers by utilizing the biological technology. The gliocladium spp. strain for suppressing the botrytis cinerea pers is gliocladium roseumWY-1 which is collected in China General Microbiological Culture Collection Center with the collection No. of CGMCCNo. 1977. The gliocladium roseum WY-1 can significantly suppress pathogens of the botrytis cinerea pers, fulvia fulva, phytophthora parasitica, verticillium dahliae of tomato, fusarium wilt of tomato, valsa sordida nit, poplar fusarium wilt and blackcurrant leaf spot, and suppress the growth of mycelia of the pathogens.

The invention provides bacillus methylotrophicus SZ-3 and SZ-81, with collection numbers of CGMCC No.8275 and CGMCC No.8276 respectively. The bacillus methylotrophicus SZ-3 has obvious antagonistic effects on pathogenic bacteria causing root rot, black spot and sclerotinia sclerotiorum of ginseng. The bacillus methylotrophicus SZ-81 has obvious antagonistic effects on pathogenic bacteria causing epidemic diseases, root rust rot and black spot of panax ginseng. The invention also provides an application of the bacillus methylotrophicus SZ-3 and SZ-81 to control of fungal diseases of plants or an application to preparation of microbial preparations for controlling fungal diseases of plants.

The invention relates to Pseudomonas chlororaphis with wide-spectrum antimicrobial activity and application of Pseudomonas chlororaphis to prevention and treatment of diseases attacking fruit trees and field crops, belonging to the field of biotechnology. The Pseudomonas chlororaphis with wide-spectrum antimicrobial activity is classified and named as Pseudomonas chlororaphis YTBTa14, with an accession number of CCTCC No. M2016099, and the 16SrDNA sequence of the Pseudomonas chlororaphis is as shown in a sequence table in the specification. The thallus and fermentation broth of the Pseudomonas chlororaphis with wide-spectrum antimicrobial activity in the invention both have good wide-spectrum antimicrobial activity to fungal diseases attacking fruit trees, have long-lasting and stable antimicrobial effect, show great potential in development into novel high-efficiency wide-spectrum bio-control fungicides, and provide a novel approach for application of microbes to biological control.

Systems are provided for preventing post harvest fungal diseases of food systems, such as but not limited to fresh produce, such as but not limited to berries (e.g., blueberries). For example, various anti-fungal compounds can incorporated or encapsulated into cyclodextrins, such as but not limited to α, β and/or γ cyclodextrins. The encapsulated anti-fungal materials can be used alone (e.g., brought into proximity to the produce) or incorporated into film and/or packaging materials that are used in the packing and/or storing of produce. By way of a non-limiting example, the anti-fungal compounds can include volatile compounds such as but not limited to acetaldehyde, hexanal and 2E-hexenal. The cyclodextrins provide controlled release of the volatiles over a period of at least several days such that they prevent or inhibit fungal growth, including but not limited to several species of the Colletotrichum, Altermaria, Botrytis, Penicillium and/or Aspergillus genera.

The invention relates to a method for recyclingly producing a trichoderma sp. biological control agent from potato starch waste water and mushroom residues and belongs to the technical field of microbial pesticides and environmental protection. The method adopts high-concentration organic wastewater produced in potato starch production and mushroom residues as main medium raw materials and utilizes a liquid state-solid state combined fermentation production method to produce the trichoderma sp. biological control agent. The method comprises the following steps of 1, inoculating potato starch wastewater as a culture medium with a trichoderma sp. strain and carrying out liquid-state culture to obtain a liquid strain, 2, inoculating potato starch waste water as a fermentation raw material with the liquid strain to obtain a large number of liquid trichoderma sp. products, 3, adding the cultured liquid strain or the liquid trichoderma sp. products into mushroom residues, and carrying out solid state fermentation to obtain solid trichoderma sp. products, and 4, carrying out drying, crushing and packaging of the solid trichoderma sp. products. The method for producing trichoderma sp. biological control agent has the characteristics of low production cost and good environmental benefits. The trichoderma sp. biological control agent obtained by the method can control a plurality of fungal diseases of plants. The method provides an effective treatment approach for high-efficiency treatment on potato starch wastewater and mushroom residues, and reduces environmental pollution.

The invention discloses a chaetomium globosum FSR-74. The collection unit of the chaetomium globosum FSR-74 is China General Microbiological Culture Collection Center, the collection date of the chaetomium globosum FSR-74 is September 19, 2014 and the collection number of the chaetomium globosum FSR-74 is CGMCC No. 9690. The strain is relatively slow in growth and has light brown colonies and an irregular wave-like edge when subjected to plate culture at 25 DEG C in a potato dextrose agar (PDA) culture medium. FSR-74 ascocarps are supergene and fixed on the surface of a matrix by rhizoids; top hair is wavy, brown and has intervals, and dense wart points are arranged on the surface; 8 ascospores are arranged in an ascus; the ascospores are shaped like lemons and have single apical bud holes. The chaetomium globosum FSR-74 has an efficient broad-spectrum bacteriostatic effect against main pathogenic bacteria causing ginseng rust rot, blight, sclerotinia rot, rust rot, blackspot, sheath blight and gray mold. The invention further provides a biological control mechanism and application of the chaetomium globosum FSR-74 in prevention and treatment of plant fungal diseases, as well as application in preparation of a microbial agent for preventing and treating the plant fungal diseases.

The present invention relates to compounds of formula (I):

or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein U, J, V, X, R^2a, R^2b, R^2c, R⁵ and t are as described herein. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. These compounds are useful for promoting cognitive function and enhancing learning and memory formation. In addition, these compounds are useful for treating, alleviating, and/or preventing various conditions, including for example, neurological disorders, memory and cognitive function disorders/impairments, extinction learning disorders, fungal diseases and infections, inflammatory diseases, hematological diseases, and neoplastic diseases in humans and animals.

Improved methods and compositions for protecting plants or seeds from plant diseases are provided. The compositions comprise (and preferably consist essentially of) saponin, such as triterpene type saponins extracted from quinoa or quillaja. Compositions according to the invention may comprise (or consist essentially of) a quantity of a sapogenin compound, preferably a sapogenins selected from the group consisting of oleanolic acid, hederagenin, phytolaccinic acid, and quillaic acid. The methods comprise contacting the portion of the plant (e.g., foliage, shoot, etc.) to be treated with a disease-inhibiting or protective amount of the composition. The compositions can also be used to treat plant seeds or tubers prior to planting thereof, as well as soil adjacent a growing plant. The inventive compositions are particularly useful for the treatment, control and/or prevention of bacterial diseases. The saponins of the invention can be applied as liquids or dry particulates, and are especially suited for the treatment of tomato and potato plants and their respective seeds.

The present invention provides Bacillus vallismortis SZ-4, which has the preservation number of CGMCC No.8273. According to the present invention, the strain grows on a beef extract-peptone (NB) culture medium in a single cell reproduction growth manner to form bacterial colonies, and the bacterial colonies have characteristics of round shape, milk white color, slightly elevated center, and moist and transparent surface; microscopic examination results show that the Bacillus vallismortis SZ-4 has a rod shape, has flagella, has a size of 0.7-0.82*1.6-2.2 mum, presents the positive Gram staining effect, has spores, and can grow on a beef extract-peptone (NB) culture medium containing 2-5% of NaCl, wherein the beef extract-peptone (NB) culture medium comprises: 3.0 g of a beef extract, 10.0 g of peptone, 5.0 g of NaCl, 17 g of agar and 1000 ml of water, and the pH value is 6.8-7.2; and the Bacillus vallismortis SZ-4 provides significant antagonism effects for pathogenic bacteria causing ginseng root rot, blight, sclerotinia sclerotiorum and botrytis cinerea. The present invention further provides an application of the Bacillus vallismortis SZ-4 in prevention and control of plant fungal diseases or preparation of microorganism preparations for prevention and control of plant fungal diseases.