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2results about How to "Fast antibacterial" patented technology

A light and dark dual-mode regulated wound microenvironment material and a preparation method and application thereof

The present application relates to a light and dark dual-mode regulation wound microenvironment material and its preparation method and application, and belongs to the technical field of biomedical functional materials. The chemical formula of the material is MoO 3‑x / Ho2O3 / N-C, MoO 3‑x / Ho2O3 nanoparticles are loaded, coated or embedded in a nitrogen-doped carbon skeleton, wherein 0<=x<=2. The present application also provides a preparation method of the material and its application in preparing treatment of infected diabetic wounds, chronic non-healing wounds, bacterial infection wounds, oxidative stress related tissue damage and vascular repair products. The light and dark dual-mode regulation wound microenvironment material provided by the present application has SOD-like and CAT-like nanoscale enzyme activity, can inhibit bacteria and kill bacteria, reduce oxidative damage, and protect fibroblasts, endothelial cells and macrophages. At the same time, it covers multiple pathological links such as bacterial infection, lactic acid accumulation, ROS excess, inflammation persistence and insufficient vascularization in infected diabetic wounds, and has more complete wound microenvironment regulation ability.
Owner:SHANDONG FIRST MEDICAL UNIV & SHANDONG ACADEMY OF MEDICAL SCI

Bimetallic nanoscale enzyme antibacterial master batch, preparation method thereof, antibacterial film and application thereof

ActiveCN121045590BEfficient antibacterialextended shelf lifePerishable foodFood packaging
The present application relates to the technical field of food packaging materials, in particular to a bimetallic nano-enzyme antibacterial master batch, a preparation method thereof, an antibacterial film and application thereof. Dimethyl imidazole, basic zinc carbonate, copper salt and epsilon-polylysine are used as raw materials for extrusion to obtain a bimetallic nano-enzyme antibacterial master batch, which is then mixed with resin for blown film to prepare an antibacterial film. The antibacterial film utilizes the characteristics of the low-coordination Cu(I) sites in the bimetallic nano-enzyme Cu-ZIF-8, i.e. ROS generation in the dark and structure collapse to release epsilon-polylysine and Cu and Zn ions in a slightly acidic environment, to achieve efficient antibacterial effect in the dark and long-term antibacterial effect for high-risk perishable food, solve the problems of poor antibacterial effect in the dark and insufficient pH adaptation of existing packaging materials, and the process is controllable and easy to industrialize.
Owner:QINGDAO AGRI UNIV