865 results about "Polylysine" patented technology

The invention relates to the technical field, and particularly discloses a nano-modified epoxy building thermal insulation material and a preparation method thereof. The nano modified epoxy building thermal insulation material is prepared from the following raw materials in parts by mass: 80 to 120 parts of Portland cement, 20 to 40 parts of slag powder, 5 to 10 parts of hollow mesoporous silicon dioxide, 0.1 to 1 part of pyrrole, 0.1 to 0.2 part of ammonium persulfate, 5 to 10 parts of nano silicon dioxide, 10 to 15 parts of bisphenol S epoxy resin, 1 to 5 parts of acrylic acid, 1 to 2 parts of polylysine, 0.01 to 0.1 part of catalyst and 1 to 2 parts of curing agent. The concrete is prepared from the following raw materials in parts by weight: 20-30 parts of epoxy resin, 4-8 parts of loaded aerogel, 0.1-1 part of polycarboxylate superplasticizer, 1-4 parts of composite fiber and 0.2-1.25 parts of hydrogen peroxide. The fireproof building material has excellent toughness, can better resist cracking and absorb energy, effectively avoids cracking and damage under the action of thermal stress, and ensures that the building material has a fireproof effect.

The invention discloses a hydrogel wound dressing for promoting healing of infectious wounds. The hydrogel wound dressing is prepared from the following raw materials: oxidized methacrylic acid hyaluronic acid, waterborne polyurethane, polylysine, cannabidiol, neomycin sulfate and 2-roots alcohol. The invention also provides a preparation method of the hydrogel wound dressing and application of the hydrogel wound dressing in preparation of products for repairing infectious wounds. The wound dressing provided by the invention has a microporous structure, good biocompatibility and biodegradability, and can be used for stopping bleeding, reducing wound infection and promoting cell proliferation and wound healing.

The invention relates to a starch-based soft capsule shell and a preparation method thereof. The starch-based soft capsule shell is prepared from the following raw materials in parts by mass: 60 to 70 parts of hydroxypropyl starch, 9 to 20 parts of carrageenan, 5 to 15 parts of diquat, 5 to 15 parts of polylysine, 5 to 10 parts of hydroxypropyl methyl cellulose acetate succinate, 15 to 20 parts of glycerol and 30 to 40 parts of pure water. According to the soft capsule shell, hydroxypropyl starch serves as a base material, gelatin is not added, the conditions of poor weather resistance and fishy smell caused by use of gelatin are avoided, through the synergistic effect of all the components, the defects that a starch-based material is poor in plasticity, fragile and insufficient in mechanical strength are overcome, the structural stability is enhanced through chemical crosslinking, and the mechanical strength is improved; and the mechanical property is improved by virtue of physical compounding, so that the low-temperature resistance, high-temperature resistance and mechanical strength of the capsule skin are improved.

The invention belongs to the technical field of biological medicines, and particularly relates to hydrogel with photo-thermal multiple antibacterial and hemostatic functions. The multifunctional hydrogel is prepared from epsilon-polylysine (EPL), gallic acid (GA), tannic acid (TA) and ferric trichloride hexahydrate. The polyphenols are obtained through multiple mechanisms such as reaction between the polyphenols and amino groups, metal chelation, pi-pi interaction and electrostatic attraction (as shown in Figure 1). The metal ion and multiple dynamic cross-linking system hydrogel is constructed, the hydrogel with positive charges enriched on the surface can act with blood platelets with negative charges, red blood cell aggregation, blood platelet adhesion and vasoconstriction effects are promoted, and the blood coagulation efficiency is improved. The hydrogel shows excellent antibacterial performance and photo-thermal performance, can prevent infection in the inflammation stage of wound healing, can effectively accelerate wound healing, and has good biological safety.

The invention provides milk exosome composite hydrogel as well as a preparation method and application thereof, and belongs to the technical field of medical materials. The milk exosome composite hydrogel provided by the invention is prepared from milk exosome, hyaluronic acid, epsilon-polylysine, 3-aminophenylboronic acid and tannic acid. The exosome is extracted from milk of a non-stem cell source; the molecular weight of the hyaluronic acid is 200 to 400 KDa. The invention provides a hydrogel carrier capable of loading a large amount of milk exosomes, and the hydrogel carrier can continuously release a large amount of milk exosomes and can give full play to the anti-oxidation and inflammation inhibition effects of the milk exosomes. In the aspect of wound healing, the milk exosome and the hydrogel carrier have a synergistic effect, so that the healing effect can be remarkably improved, and the healing period is shortened.

The invention discloses a compound feed for raising plateau live pigs and a preparation method thereof, and relates to the technical field of feed processing. The compound feed for raising the plateau live pigs is prepared from manganese-selenium compound modified charcoal, soybean polysaccharide polylysine-based supported nanoparticles, aspergillus oryzae, soybean meal powder, corn flour, wheat bran, mountain flour, calcium hydrophosphate, table salt and multivitamins. Manganese-selenium composite modified charcoal, soybean polysaccharide polylysine-based supported nanoparticles and aspergillus oryzae are subjected to co-fermentation culture to form a uniform, stable, loose and porous three-dimensional network fermentation substrate composite system, so that the damage of gastric acid to components is reduced, the targeted release of intestinal tracts is realized, and the bioavailability is improved. The composite functional additive which is high in nutrition, easy to absorb, anti-oxidation, anti-anemia, anti-ultraviolet radiation and the like is obtained, and the adverse effects of low temperature, oxygen deficit and ultraviolet factors on animal growth and feed oxidative rancidity are effectively reduced.

The invention discloses a bullfrog extracted biological collagen composition and a preparation method thereof in the technical field of collagen. The bullfrog extracted biological collagen composition comprises the following components in parts by weight: 1-1.5 parts of hydrophobic bullfrog source collagen peptide, 0.6-0.8 part of hydrophobic bullfrog source elastin peptide, 1-1.5 parts of polyglutamic acid and 1-1.5 parts of polylysine. Collagen and elastin in bullfrog skin and bullfrog cartilage are extracted in a combined mode through a three-enzyme co-production method, and after bullfrog source collagen peptide and bullfrog source elastin peptide are subjected to hydrophobic modification, polyglutamic acid and polylysine are added to form a collagen combination. The stability, the medicine carrying capacity and the slow release capacity of the composition can be improved.

The invention provides a preparation method of NMN nano microspheres with high stability, and belongs to the technical field of NMN. The preparation method comprises the steps of NMN pretreatment, primary microsphere preparation, functional microsphere preparation and mixing. The preparation method of the primary microspheres comprises the following steps: adding epsilon-polylysine and glutathione into an ethanol solution, uniformly stirring, adding 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide, and stirring for 28-32 minutes to obtain a mixed solution; adding the pretreated NMN solution into the chitosan solution, then adding the mixed solution, and carrying out heat preservation at 44-50 DEG C for 2.8-3.2 h to obtain primary microspheres; the NMN nano-microsphere prepared by the method disclosed by the invention is good in stability and good in slow release performance.

The invention discloses a preparation method and application of a composite PVDF-HFP and polylysine nanofiber diaphragm, and belongs to the technical field of lithium batteries. The composite material is prepared by blending polyvinylidene fluoride-hexafluoropropylene (PVDF-HFP) and polylysine and then carrying out an electrostatic spinning process. The PVDF-HFP is utilized to provide excellent mechanical strength and chemical stability, rich polar amino functional groups in a polylysine molecular chain are utilized to improve the lyophilic property of the membrane, and anions in an electrolyte are fixed through an intermolecular acting force, so that the transference number of lithium ions is increased, and the lithium ions are induced to be uniformly deposited. The nanofiber membrane combines the characteristics of PVDF-HFP and polylysine, has high porosity, good thermal stability and excellent interface compatibility, can effectively inhibit the growth of lithium dendrites and prevent the diaphragm from being punctured, and can significantly prolong the cycle life and improve the safety performance of the lithium metal battery when being applied to the lithium metal battery.

The present invention relates to a composition (the composition of the invention) comprising a component A consisting of a polylysine component, an XL component and a fibrous component consisting of at least one fibrous element comprising plant fibers, and wherein the fibrous element is free of any fibers other than plant fibers, and wherein the component A comprises a polylysine component, an XL component, and a fibrous component consisting of at least one fibrous element comprising plant fibers. And wherein the composition is free of any fibers other than the plant fibers of the fiber component. The invention further relates to a method for obtaining an object from the composition according to the invention. The invention further relates to objects (objects of the invention) obtained by said method, such as sheets, strips, bars, strips, films, cloths, containers, panels, panels, beams, frames, slats, engineered wood, such as fiberboards. The invention further relates to an article (article of the invention) comprising a) a component that is solid at 23 DEG C and 1 atm; and one or both of b) and c) wherein b) is the composition of the invention and c) is the object of the invention. The invention further relates to various uses of any one or any combination of the composition of the invention, the object of the invention and the article of the invention.

The invention relates to epsilon-polylysine epsilon-PL-loaded modified rice bran protein antibacterial nanoparticles as well as a preparation method and application thereof, and belongs to the technical field of preparation of nanoparticles. The preparation method comprises the following steps: extracting rice bran protein from defatted rice bran to prepare a rice bran protein stock solution; under continuous stirring, adding succinic anhydride into the rice bran protein stock solution to obtain acylated rice bran protein; mixing the acylated rice bran protein stock solution, the lactose stock solution and the epsilon-PL stock solution; and centrifuging and freeze-drying to obtain the epsilon-PL-loaded modified rice bran protein antibacterial nanoparticles. The preparation method disclosed by the invention is simple and low in cost, the prepared nanoparticles have smaller particle size and turbidity and higher stability, the hygroscopicity of epsilon-PL can be reduced to a great extent, the bioavailability of epsilon-PL can be improved, and the nanoparticles have an obvious bacteriostatic effect on escherichia coli and staphylococcus aureus.

The invention discloses an antibacterial anti-mite composite fabric and a preparation method and application thereof, and relates to the technical field of functional fabrics, the antibacterial anti-mite composite fabric comprises the following raw materials by mass: 10-20% of bamboo fiber, 10-20% of alginate fiber, and 60-80% of photo-thermal antibacterial modified cotton fiber; the photo-thermal antibacterial modified cotton fiber is prepared from the following raw materials in parts by weight: 1 to 2 parts of pretreated cotton fiber, 0.02 to 0.12 part of graphene oxide titanium dioxide composite material coated polydopamine-epsilon-polylysine antibacterial agent and 150 to 400 parts of water, the mass ratio of the pretreated cotton fiber to the graphene oxide titanium dioxide composite material coated polydopamine-epsilon-polylysine antibacterial agent is 1: (0.02-0.06). The composite fabric provided by the invention has excellent antibacterial rate and mite repelling rate, and also has excellent photo-thermal antibacterial and mite-killing characteristics.

The present invention relates to a composition (the composition of the invention) comprising a component A consisting of a polylysine component, an XL component and a fibrous component consisting of at least one fibrous element comprising plant fibers, and wherein the fibrous element is free of any other fibers other than plant fibers, and wherein the component A consists of a polylysine component, an XL component, and a fibrous component consisting of at least one fibrous element comprising plant fibers. And the composition does not contain any fibers other than the plant fibers of the fiber component. The invention further relates to a method for obtaining an object from the composition according to the invention. The invention further relates to objects (objects of the invention) obtained by said method, such as sheets, strips, bars, strips, films, cloths, containers, panels, panels, beams, frames, slats, engineered wood, such as fiberboards. The invention further relates to an article (article of the invention) comprising a) a component that is solid at 23 DEG C and 1 atm; and one or both of b) and c) wherein b) is the composition of the invention and c) is the object of the invention. The invention further relates to various uses of any one or any combination of the composition of the invention, the object of the invention and the article of the invention.

The invention provides a wound dressing for diminishing inflammation, easing pain and promoting wound healing and a preparation method thereof. The wound dressing capable of diminishing inflammation, easing pain and promoting wound healing is prepared from the following components in parts by mass: 6 to 10 parts of oxidized sodium alginate, 7 to 9 parts of hydrazide gelatin, 1 to 1.5 parts of tannic acid, 8 to 12 parts of polyethylene glycol, 0.05 to 0.1 part of cannabidiol, 0.05 to 0.1 part of neomycin sulfate, 0.2 to 0.3 part of 2-roots alcohol, 0.02 to 0.04 part of vitamin C palmitate and 0.03 to 0.1 part of epsilon-polylysine. The dressing can achieve excellent effects of diminishing inflammation, easing pain and promoting wound healing through synergistic cooperation of all the components.

The invention provides glycosaminoglycan hydrogel with a physical and chemical double crosslinking mechanism as well as a preparation method and application thereof, and relates to the technical field of biological materials. The glycosaminoglycan hydrogel is prepared from the following raw materials: oxidized sodium hyaluronate, chondroitin sulfate, epsilon-polylysine hydrochloride, a polydopamine-titanium dioxide compound and a stabilizer. The glycosaminoglycan hydrogel is prepared through a physical and chemical double-crosslinking mechanism under the specific raw materials and proportion, the problems of cytotoxicity and the like caused by use of a crosslinking agent or introduction of other solvents are avoided, a stable covalent network is constructed through chemical crosslinking, the gel is endowed with the self-repairing characteristic through physical crosslinking, and the self-repairing performance of the hydrogel is improved. And the viscosity of the product is remarkably improved, so that the hydrogel has stronger mechanical support performance, is suitable for wound repair, wound healing and the like, and has good antibacterial activity and stability.

The present invention relates to a composition (the composition of the invention) comprising a component A consisting of a polylysine component, an XL component and a fibrous component consisting of at least one fibrous element comprising plant fibers, and wherein the fibrous element is free of any fibers other than plant fibers, and wherein the component A comprises a polylysine component, an XL component, and a fibrous component consisting of at least one fibrous element comprising plant fibers. And wherein the composition is free of any fibers other than the plant fibers of the fiber component. The invention further relates to a method for obtaining an object from the composition according to the invention. The invention further relates to objects (objects of the invention) obtained by said method, such as sheets, strips, bars, strips, films, cloths, containers, panels, panels, beams, frames, slats, engineered wood, such as fiberboards. The invention further relates to an article (article of the invention) comprising a) a component that is solid at 23 DEG C and 1 atm; and one or both of b) and c) wherein b) is the composition of the invention and c) is the object of the invention. The invention further relates to various uses of any one or any combination of the composition of the invention, the object of the invention and the article of the invention.

The present invention relates to a composition (the composition of the invention) comprising a component A consisting of a polylysine component, an XL component and a fibrous component consisting of at least one fibrous element comprising plant fibers, and wherein the fibrous element is free of any other fibers other than plant fibers, and wherein the component A consists of a polylysine component, an XL component, and a fibrous component consisting of at least one fibrous element comprising plant fibers. And the composition does not contain any fibers other than the plant fibers of the fiber component. The invention further relates to a method for obtaining an object from the composition according to the invention. The invention further relates to objects (objects of the invention) obtained by said method, such as sheets, strips, bars, strips, films, cloths, containers, panels, panels, beams, frames, slats, engineered wood, such as fiberboards. The invention further relates to an article (article of the invention) comprising a) a component that is solid at 23 DEG C and 1 atm; and one or both of b) and c) wherein b) is the composition of the invention and c) is the object of the invention. The invention further relates to various uses of any one or any combination of the composition of the invention, the object of the invention and the article of the invention.

The invention discloses a preparation method of injectable hemostatic glue, which comprises the following steps: step 1, synthesizing oxidized hyaluronic acid: dissolving hyaluronic acid in distilled water, adding NaIO4, stirring, dialyzing a reaction product after the reaction is finished, and then freeze-drying to obtain the oxidized hyaluronic acid; the epsilon-polylysine and the oxidized hyaluronic acid obtained in the step 1 are dissolved in a PBS buffer solution, an oxidized hyaluronic acid solution and an epsilon-polylysine solution are mixed, the epsilon-polylysine / oxidized hyaluronic acid hydrogel can be obtained, and the pH value of the mixed solution is preferably 5.0-13.0. According to the method, the hemostatic gel solution can be injected to visceral hemorrhage and external hemorrhage, is gelled in situ at a wound, can be automatically degraded in vivo, and can be taken out without an operation. Taking a liver hemorrhagic point as an example, the hydrogel effectively solves the problem of closed bleeding of the liver. The preparation method provided by the invention is mild in condition and convenient to operate, and gel forming is easy to control.

The invention relates to a soil remediation complex microbial inoculant composition and a preparation method thereof, and belongs to the technical field of soil remediation. Comprising the following raw materials: 10-15 parts of a microbial complex inoculant, 40-50 parts of a porous carrier, 20-25 parts of an organic matter and 3-5 parts of a surface protective agent, wherein the porous carrier is obtained by treating diatomite with phytic acid and polylysine. Paenibacillus polymyxa, trichoderma harzianum, bacillus subtilis and azotobacter chroococcum are taken as a microbial compound inoculant, modified diatomite is taken as a porous carrier, and the microbial compound inoculant is mixed with organic matters under the action of a protective agent, so that the soil remediation compound inoculant composition which can effectively improve soil and is excellent in strain activity is obtained.

The present invention relates to a composition (the composition of the invention) comprising a component A consisting of a polylysine component, an XL component and a fibrous component consisting of at least one fibrous element comprising plant fibers, and wherein the fibrous element is free of any fibers other than plant fibers, and wherein the component A comprises a polylysine component, an XL component, and a fibrous component consisting of at least one fibrous element comprising plant fibers. And wherein the composition is free of any fibers other than the plant fibers of the fiber component. The invention further relates to a method for obtaining an object from the composition according to the invention. The invention further relates to objects (objects of the invention) obtained by said method, such as sheets, strips, bars, strips, films, cloths, containers, panels, panels, beams, frames, slats, engineered wood, such as fiberboards. The invention further relates to an article (article of the invention) comprising a) a component that is solid at 23 DEG C and 1 atm; and one or both of b) and c) wherein b) is the composition of the invention and c) is the object of the invention. The invention further relates to various uses of any one or any combination of the composition of the invention, the object of the invention and the article of the invention.

The invention relates to the technical field of organic fertilizers, in particular to a long-acting slow-release charcoal-based microbial compound fertilizer and a preparation method thereof. The long-acting slow-release biochar-based microbial organic fertilizer is prepared from the following raw materials in parts by mass: 10 to 20 parts of corn grit, 5 to 10 parts of coated biochar, 1 to 3 parts of monopotassium phosphate, 30 to 40 parts of livestock and poultry manure, 0.001 to 0.01 part of lanthanum ammonium nitrate, 30 to 40 parts of inorganic fertilizer, 0.2 to 0.3 part of microbial agent and 1.5 to 2 parts of epsilon-polylysine, the coated biochar is prepared by the following steps: adding biochar and dopamine hydrochloride into water, mixing, stirring at 30-40 DEG C for 20-30 minutes, adding tris (hydroxymethyl) aminomethane, stirring for 20-30 hours, centrifuging, washing, drying, crushing, feeding into a tubular furnace, keeping the temperature at 300-500 DEG C for 20-40 minutes under the protection of nitrogen, and cooling to room temperature.

The present invention relates to a composition (the composition of the invention) comprising a component A consisting of a polylysine component, an XL component and a fibrous component consisting of at least one fibrous element comprising plant fibers, and wherein the fibrous element is free of any fibers other than plant fibers, and wherein the component A comprises a polylysine component, an XL component, and a fibrous component consisting of at least one fibrous element comprising plant fibers. And wherein the composition is free of any fibers other than the plant fibers of the fiber component. The invention further relates to a method for obtaining an object from the composition according to the invention. The invention further relates to objects (objects of the invention) obtained by said method, such as sheets, strips, bars, strips, films, cloths, containers, panels, panels, beams, frames, slats, engineered wood, such as fiberboards. The invention further relates to an article (article of the invention) comprising a) a component that is solid at 23 DEG C and 1 atm; and one or both of b) and c) wherein b) is the composition of the invention and c) is the object of the invention. The invention further relates to various uses of any one or any combination of the composition of the invention, the object of the invention and the article of the invention.

A deodorant stick composition comprising (i) a glycol selected from propylene glycol (PG) and / or dipropylene glycol (DPG); (ii) water; (iii) a structurant; and (iv) polylysine.

The invention provides a bacteriostatic PET (polyethylene terephthalate) coiled material as well as a preparation method and application thereof, and belongs to the technical field of high polymer materials, the bacteriostatic PET coiled material is prepared from the following raw materials: PET, nano titanium dioxide, nano talcum powder, a compatilizer, an antioxidant, a lubricant and a modified composite bacteriostatic agent; the compatilizer is an ethylene-methyl acrylate-glycidyl methacrylate random terpolymer and / or an ethylene-acrylic ester-maleic anhydride random terpolymer, and the compatilizer is an ethylene-methyl acrylate-glycidyl methacrylate random terpolymer and / or an ethylene-acrylic ester-maleic anhydride random terpolymer; the lubricant is one or a mixture of two of pentaerythritol stearate, erucyl amide, polyethylene wax, polyvinyl alcohol and ethylene bis stearamide; the modified composite bacteriostatic agent is prepared from catechin gallate, epsilon-polylysine hydrochloride and modified porous zinc oxide. The prepared antibacterial PET coiled material can be used for packaging materials of packaging boxes, lunch boxes, cup covers, trays and the like, and has good mechanical properties such as bending strength and impact strength and excellent antibacterial performance.

The invention relates to a heparinized gelatin / sodium alginate pancreas islet packaging material with an anti-fibrosis function as well as a preparation method and application of the heparinized gelatin / sodium alginate pancreas islet packaging material. The preparation method comprises the following steps: adding gelatin into normal saline, soaking, performing autoclaved sterilization to obtain a gelatin solution, then adding epsilon-polylysine hydrochloride into the gelatin solution, and finally adding glutamine transaminase for reaction to obtain an epsilon-polylysine grafted gelatin solution; adding heparin into the solution, and reacting to obtain a heparinized gelatin solution; adding sodium alginate and glutamine transaminase, reacting, diluting, preparing hydrogel microspheres by adopting an electrostatic spraying method, and cross-linking to obtain the hydrogel microspheres. According to the invention, heparin molecules are incorporated into a pancreas islet packaging system, so that fibrosis at the periphery of the microspheres can be relieved, the pancreas islet cells are packaged by using the pancreas islet packaging material to prepare the biological artificial pancreas, the pancreas islet cell proliferation and insulin secretion can be promoted, and the pancreas islet packaging material has a good diabetes treatment effect.

The invention discloses a degradable photo-thermal antibacterial composite film based on MXene loaded epsilon-polylysine as well as preparation and application of the degradable photo-thermal antibacterial composite film. The preparation method comprises the following steps: firstly, preparing an MX-PL composite nanomaterial from successfully etched MXene and epsilon-PL through an electrostatic self-assembly effect, then adding the MX-PL composite nanomaterial into a chitosan membrane solution containing a glycerin plasticizer, uniformly stirring, carrying out ultrasonic degassing, and then preparing the photo-thermal antibacterial and degradable packaging film through a solvent casting method. The defect that the antibacterial activity is hindered due to the fact that positive ions epsilon-PL easily interact with negative ion components of a food matrix is overcome, and the two-dimensional nanoparticles capable of achieving photo-thermal antibacterial performance are obtained.

The invention relates to the technical field of polyolefin materials, in particular to a mildewproof and antibacterial polyolefin material and a processing technology and application thereof. The mildew-proof antibacterial polyolefin material comprises the following components in parts by weight: 60-80 parts of polypropylene, 5-15 parts of an elastomer, 2-5 parts of maleic anhydride grafted polypropylene, 15-25 parts of white oil, 10-30 parts of talcum powder, 1-5 parts of a mildew-proof antibacterial agent, 0.5-1.0 part of an antioxidant and 1-3 parts of a lubricant. The mildew-proof antibacterial agent is a mixture prepared from 0.5 to 2.0 parts of modified nano zinc oxide, 0.3 to 1.5 parts of methylisothiazolinone and 0.2 to 1.5 parts of epsilon-polylysine hydrochloride. The mildew-proof and antibacterial polyolefin material prepared by the invention has excellent mechanical properties and mildew-proof and antibacterial properties.

The invention relates to absorbable adhesive styptic powder and a preparation method thereof, and the absorbable adhesive styptic powder is characterized in that the absorbable adhesive styptic powder is formed by cross-linking aldehyde polysaccharide and a polyamino compound through Schiff base reaction, the raw materials are selected from at least one of glucan, sodium carboxymethyl cellulose, sodium hyaluronate, chitosan and carboxymethyl starch; the polyamino compound is selected from at least one of polylysine, polypeptide, bovine serum albumin and polyamine; the styptic powder is porous particles with the particle size of 10-1000 meshes, is cured into gel within 10 seconds after being in contact with body fluid, and is completely degraded within 15-60 days. According to the scheme, the styptic powder has the advantages of rapid wet adhesion, controllable degradation and excellent processability, and is an urgent clinical demand.

The present invention relates to the field of fiber materials, and discloses a UHMWPE composite fiber with a functional coating and a preparation method thereof. The composite fiber comprises a UHMWPE fiber bundle with a three-dimensional woven structure, and a phenolamine co-deposition modification layer, an inorganic functional nanoparticle deposition layer, and a silk fibroin / polylysine cross-linked porous layer sequentially coated on the surface of the fiber bundle. The present invention sequentially deposits phenolamine and NPs on the surface of the UHMWPE fiber bundle with a three-dimensional woven structure, then constructs a silk fibroin coating with a microporous structure on the surface of the inorganic functional nanoparticle deposition layer to coat the NPs to improve the stability of the NPs, and then self-assembles polylysine with an antibacterial effect with the silk fibroin through electrostatic adsorption, and finally forms a silk fibroin / polylysine cross-linked porous layer after cross-linking. The UHMWPE composite fiber of the present invention has excellent mechanical properties, stability, antibacterial properties and bone regeneration promoting properties.

The embodiment of the invention provides nano-enzyme hydrogel for promoting scar-free wound repair through inflammation regulation and c-Jun gene silencing and a preparation method of the nano-enzyme hydrogel. The nano-enzyme hydrogel is prepared from the following components in parts by mass: synthesized epsilon-polylysine modified CeO2 nano-enzyme particles and aldehyde hyaluronic acid, an instant Schiff base reaction between epsilon PL-CeO2 surface amino groups and HA-CHO molecule aldehyde groups is utilized, in-situ mixing is performed to form a hydrogel network, in addition, bFGF and siRNA are loaded into PLGA microspheres, and the hydrogel network is formed through in-situ mixing. And further embedding into the hydrogel to obtain the nano-enzyme hydrogel. The obtained nano-enzyme hydrogel has the functions of inflammation regulation, cell proliferation promotion, vascular regeneration promotion, c-Jun gene silencing and the like, and scar-free healing of skin wounds is remarkably promoted.