4544 results about "W o emulsion" patented technology

The present disclosure relates to methods, compositions and systems for droplet processing. For example, methods can include (a) providing a first emulsion comprising a first droplet population, wherein droplets of the first droplet population comprise a lysis reagent, and a second emulsion comprising a second droplet population, wherein a droplet of the second droplet population comprises i) a cell or a nucleus, and ii) a plurality of nucleic acid barcode molecules; (b) subjecting the first emulsion and second emulsion to conditions sufficient to transfer the lysis reagent to the second droplet population via micelles comprising the lysis reagent; and (c) lysing the cell or the nucleus within the droplet of the second droplet population with the lysis reagent.

The invention discloses a self-crosslinking temperature-resistant salt-resistant emulsion type fracturing fluid thickening agent and a preparation method thereof, and belongs to the technical field of oilfield chemistry. The raw materials adopted by the invention comprise 30 to 50 parts of an oily solvent, 15 to 25 parts of deionized water, 10 to 20 parts of acrylamide, 5 to 10 parts of acrylic acid, 2 to 4 parts of 2-acrylamido-2-methylpropanesulfonic acid, 0.05 to 0.2 part of a crosslinking monomer, 0.5 to 1 part of a quaternary ammonium salt type hydrophobic association monomer, 4 to 8 parts of an emulsifier and 1 to 2 parts of a phase inversion agent. The self-crosslinking emulsion is formed through water phase-oil phase mixing, high-speed emulsification, low-temperature initiation polymerization and phase inversion treatment. Based on physical-chemical double-crosslinking temperature control cooperation, a salt-resistant-hydrophobic double-shielding mechanism and an integrated design without an exogenous crosslinking agent, the contradiction between the temperature-resistant and salt-resistant performance of a traditional thickening agent and the process complexity is broken through, and a technical support is provided for efficient development of high-temperature and high-salt oil and gas reservoirs.

The invention provides a PHA dispersion emulsion as well as a preparation method and application thereof, and belongs to the field of high polymer materials. The invention aims to solve the technical problem that the prior art cannot simultaneously meet the requirements of the polyhydroxyalkanoate water dispersion system on extremely low temperature natural film-forming property, excellent comprehensive performance after film formation and long-term storage stability. The method is characterized in that a polyhydroxyalkanoate polymer with specific molecular weight and polydispersity index range, a coalescing agent 2, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate with a specific chemical structure and a specific type of aliphatic polyisocyanate cross-linking agent compatible with water dispersion are strictly limited and combined. Through the synergistic effect generated by the unique ternary combination, the minimum film forming temperature of the prepared emulsion can be reduced to 6-10 DEG C, a film can be naturally formed without hot pressing, and the formed film has excellent mechanical property, water resistance and adhesive force and has excellent storage stability of at least one year.

The invention discloses a method for preparing a high-stability W / O / W type multiple Pickering emulsion based on Janus particles, and belongs to the technical field of colloid and interface chemistry. According to the preparation method, the Janus particles with different hydrophilic and hydrophobic properties are prepared by using alkylsilane modified SiO2 with different chain lengths, the multiple emulsion is stabilized together, different types of Janus particles are adsorbed on different oil-water interfaces, and the interface activity and amphipathicity of the Janus particles are fully exerted to prepare the high-stability multiple emulsion. The multi-emulsion provided by the invention has excellent stability, keeps stable under the conditions of long-term storage, strong acid, strong alkali, high-concentration electrolyte and the like, and can effectively expand the practical application of the multi-emulsion.

According to the stable organic silicon emulsion and the preparation method thereof provided by the invention, polyglycerol ricinoleate with different polymerization degrees, polydihydric alcohol oleate with different molecular weights and silicon polyether are introduced, so that the emulsifying capacity of the emulsion is improved, and the stability of the emulsion is improved; the polyglycerol ricinoleate serving as an emulsifier and a stabilizer can disperse water-soluble substances and oil-soluble substances, so that all the components are uniformly mixed, the emulsification is more sufficient, and the stability of the emulsion is improved; the emulsion enters the emulsification pump for emulsification under the condition of high rotating speed, so that the particle size of the emulsion is smaller, and the stability is better.

The invention provides water-in-oil type emulsion gel loaded with probiotics and a preparation method of the water-in-oil type emulsion gel, and belongs to the technical field of probiotic products, the water-in-oil type emulsion gel loaded with the probiotics comprises a water phase and an oil phase, and the internal water phase is composed of gel and probiotic suspension; and the external oil phase consists of edible oil, a lipophilic emulsifier and at least one oil gelator. According to the water-in-oil emulsion gel, the stability of entrapped probiotics can be remarkably improved, meanwhile, the activity of the entrapped probiotics in the processing, storage and digestion processes is improved, particularly, the normal-temperature storage time is prolonged by 3 months, and a scientific basis is provided for normal-temperature food development.

The invention discloses a method for preparing a high internal phase emulsion and delivering curcumin by using transglutaminase mediated casein-carboxymethyl chitosan covalent substances, aims to improve the stability and bioaccessibility of curcumin, and belongs to the field of food processing. The method comprises the following steps: firstly, carrying out ultrasonic treatment on sodium caseinate for a certain time, and carrying out transglutaminase cross-linking reaction on sodium caseinate and carboxymethyl chitosan to obtain a casein-carboxymethyl chitosan covalent substance; and then adding the mixture into the curcumin-loaded corn oil according to a certain proportion, and homogenizing to obtain the curcumin-loaded high internal phase emulsion. The emulsion has good interface characteristics and can effectively encapsulate curcumin. The preparation process is simple, efficient, green and environmentally friendly, the prepared high internal phase emulsion has high stability and good biological accessibility, a new technical means is provided for delivery of curcumin, and the high internal phase emulsion has wide application prospects in the field of food.

The application belongs to the technical field of daily chemical industry, and particularly relates to an emulsion and a preparation method thereof. The emulsion provided in the application comprises an emulsifier, glycerol, oil-phase active substance, pentaerythritol tetra(ethylhexanoate) and water; the emulsifier is a lipopeptide; the weight percentage of the lipopeptide and the glycerol is not less than 3%; the weight ratio of the oil-phase active substance and the pentaerythritol tetra(ethylhexanoate) is 1:3-10; the ratio of the sum of the weights of the lipopeptide and the glycerol to the sum of the weights of the oil-phase active substance and the pentaerythritol tetra(ethylhexanoate) is 1:3-10; and the ratio of the sum of the weights of the lipopeptide, the glycerol, the oil-phase active substance and the pentaerythritol tetra(ethylhexanoate) to the weight of the water is 1:1-4. The emulsion is prepared by using sodium bacillomycin, glycerol and pentaerythritol tetra(ethylhexanoate), can effectively inhibit the diffusion of the oil-phase active substance at the interface of the emulsion, reduce the oxidative degradation of the oil-phase active substance, and greatly prolong the effective action time of the oil-phase active substance in the emulsion.

The invention relates to the technical field of preparation of antibacterial gloves, in particular to a preparation method of degradable breathable antibacterial gloves, and an emulsion formula of the degradable breathable antibacterial gloves comprises the following components in parts by weight: 100 parts of nitrile rubber modified polylactic acid, 5-10 parts of modified antibacterial filler, 1-3 parts of an anti-aging agent, 0.5-3 parts of a vulcanizing agent, 0.3-2 parts of a vulcanization accelerator and 0.5-1 part of a foaming agent. Through a high-molecular compound composition system, nitrile rubber modified polylactic acid, modified antibacterial filler and other components are compounded to prepare the glove with controllable degradability, lasting antibacterial property and good air permeability; on the basis of covalent binding of silicon dioxide loaded with antibacterial groups and modified chitosan, the synergistic antibacterial effect of the modified antibacterial filler is achieved, and therefore the antibacterial performance of the glove is improved.

The invention discloses an acrylic acid composite emulsion coating and a preparation method thereof, and relates to the technical field of novel coatings. The acrylic acid composite emulsion coating comprises the following components in parts by mass: 30-50 parts of an acrylate monomer mixture, 1-8 parts of a functional monomer, 0.5-3 parts of a protective colloid, 1.5-5 parts of an emulsifier, 0.2-1.5 parts of an initiator, 40-60 parts of deionized water and 1-3 parts of a weather-resistant agent. The coating adopts a water-based system and takes water as a dispersion medium, so that the use of an organic solvent is reduced, the emission of volatile organic compounds (VOC) is remarkably reduced, and the coating is more environment-friendly. By adding the weather-resistant agent with a specific structure, free radicals can be effectively captured, an oxidation chain reaction can be interrupted, and the weather resistance of the coating is improved through the synergistic effect of multiple mechanisms, so that the phenomena of pulverization, color fading, cracking and the like are unlikely to occur under the action of environmental factors such as ultraviolet rays, oxygen and water vapor.

The invention discloses a high-stability endotoxin-free PHA nano-emulsion and a preparation method thereof, and belongs to the technical field of biodegradable high polymer material compositions and processing thereof. The nano-emulsion is characterized in that the endotoxin content is not higher than 0.10 EU / g, the median particle size d50 is 100-200 nm, and the PDI is not higher than 0.15, and the nano-emulsion is stable in long-term storage. The preparation method is a continuous solvent-free process and comprises the steps of melt extrusion, high-pressure thermal emulsification and deep endotoxin removal. By adopting the specific pH-insensitive cationic polymer emulsifier and the crystallization inhibitor, the chemical contradiction that an efficient alkaline purification process is incompatible with a nano-emulsion stable system is solved, physical aging is inhibited, and an unexpected technical effect is obtained. The invention also discloses an O / W type cream containing the nano emulsion.

The invention discloses a method for determining the critical safety diameter of an emulsion drop of a liquid energetic material synthesis reaction conveying pipeline, which comprises the following steps of: curing and heating a sampled emulsion, determining pyrolysis kinetic parameters of the detected emulsion, constructing a heat production and heat transfer heat insulation system model of a mixed solution of an acid ester emulsion and the emulsion drop by utilizing Comsol, and determining the critical safety diameter of the emulsion drop of the liquid energetic material synthesis reaction conveying pipeline. Calculating a temperature rise change rule of the mixed liquid heat insulation system under different emulsion droplet sizes, determining a function relationship between the emulsion droplet particle size and the temperature rise of the mixed liquid heat insulation system, and deriving to obtain the critical safety diameter of the emulsion droplet; the method comprises the following steps: adsorbing emulsified liquid by using a porous particle material, testing whether the emulsified liquid explodes due to collision and friction of emulsified liquid with different pore diameters at different rates in an impact tank-piston device to obtain the relationship among the movement rate of emulsified liquid drops, the particle size of the emulsified liquid drops and the explosion risk, and determining the explosion risk of the emulsified liquid drops under a specific conveying speed condition according to the relationship. The liquid energetic material is used for synthesizing the optimal size of emulsified liquid drops in a reaction mixed solution.

The invention belongs to the field of pharmaceutical preparations, and relates to a brexpiprazole long-acting microsphere and a preparation method thereof, and the preparation method comprises the following steps: (1) dissolving brexpiprazole and a degradable polymer in an organic solvent to obtain a drug-containing polymer solution as an oil phase; (2) mixing the drug-containing polymer solution with a polyvinyl alcohol solution through a microfluidic technology to obtain an oil-in-water emulsion; and (3) under a stirring condition, carrying out curing, washing and freeze drying on the oil-in-water type emulsion to obtain the brexpiprazole long-acting microspheres. By adjusting the volatilization stirring time when the O / W primary emulsion is formed, the final in-vitro release rate of the microspheres is adjusted, and the microspheres which are free of burst release and hysteresis period and are slowly released can be screened out. The brexpiprazole long-acting microsphere provided by the invention is simple in preparation process, easy to industrially amplify, high in encapsulation efficiency, large in drug loading capacity, uniform in microsphere particle size distribution, round in shape, good in flowability and good in needle passing property, is easier to inject, has an obvious slow release effect, and can be used for reducing the fluctuation of blood concentration and effectively improving the compliance of psychiatric patients.

The invention belongs to the technical field of functional Pickering emulsion preparation, and particularly discloses a silk fibroin nanoparticle-stabilized biphase drug-loaded Pickering emulsion and an antibacterial application thereof. The curcumin-loaded silk fibroin nanoparticles Cur-SFNPs with uniform form and size are prepared by using an anti-solvent precipitation method. In order to improve the antibacterial effect of the Pickering emulsion, the Cur-SFNPs is utilized to stabilize the soybean oil loaded with resveratrol, and the oil-in-water type Pickering emulsion is prepared. The Pickering emulsion prepared by taking Cur-SFNPs as a stabilizer has the characteristics of small particle size, uniform distribution, storage stability, heating stability, freeze-thaw stability, food safety and environmental friendliness. And as a two-phase drug-loaded emulsion, two natural hydrophobic active drugs are loaded at the same time, so that the solubility and bioavailability of the emulsion can be enhanced, the loaded active substances play a synergistic antibacterial and antioxidant role, and the emulsion can be applied to food preservation.

The present invention relates to pro-nano-emulsion compositions comprising at least one type of Omega 3 fatty acid capable of converting to nano-emulsion composition having average droplet size of below Ip, typically below 0.5p, and use thereof, particularly as dietary supplement, for preferential delivery of the Omega 3 fatty acid to heart and / or liver tissue of a subject consuming the composition, thereby maintaining normal cardiovascular / hepatic function and / or improving cardiovascular / hepatic disease or disorders.

The invention relates to a preparation method of a core-shell fluorine-free super-hydrophobic emulsion based on acrylate pressure-sensitive adhesive viscosity. According to the method, a polyacrylate pressure-sensitive adhesive is adopted, an acrylate soft monomer and a functional monomer are copolymerized on the surface layer of the polyacrylate pressure-sensitive adhesive, and a polyacrylate copolymer with pressure-sensitive adhesiveness and reaction activity is coated to obtain a pressure-sensitive adhesive'rigid core at flexible shell 'core-shell polymer microsphere emulsion with a core-shell structure; the production process is simplified (two steps are combined into one step), and chromatic aberration is eliminated; the silane coupling agent can be used for replacing a silane coupling agent, and the problem of insufficient durability is further solved. According to the invention, the simplification and batch production of the production process can be effectively realized, and meanwhile, the requirements of modern industry on economic and green production can be met.

The invention discloses a modified hydroxyl acrylic emulsion and a preparation method thereof, and belongs to the technical field of environment-friendly paints.The modified hydroxyl acrylic emulsion is prepared from, by weight, 35-50 parts of acrylate monomer, 5-10 parts of functional monomer, 5-10 parts of hydroxyethyl acrylate, 0.3-1.5 parts of initiator, 1-2 parts of vinyl siloxane, 1-2 parts of emulsifier, 0.3-1 part of neutralizer and 30-50 parts of deionized water; the preparation method comprises the following steps: adding an acrylate monomer, a functional monomer, hydroxyethyl acrylate and vinyl siloxane into deionized water, adding an initiator and an emulsifier, heating to 60-75 DEG C, stirring at a constant speed for 30 minutes, and adding a neutralizer to prepare a modified hydroxyl acrylic emulsion; a functional monomer structure contains an antibacterial dichloropyrimidine monomer structure, a main body is an acrylic acid structure and has good compatibility with a matrix, a siloxane structure is introduced, a large number of hydroxyl groups are generated after hydrolysis, and the bonding performance with the coating matrix can be improved.

The invention relates to the field of PMMA emulsion, in particular to high-ionic-conductivity PMMA glue and a preparation method thereof.The high-ionic-conductivity PMMA glue is prepared from, by weight, 80-90 parts of PMMA emulsion, 2-3 parts of modified beta-kaliophilite and 1-3 parts of thickening agent. The PMMA glue with high ionic conductivity prepared by the invention has the characteristics of good mechanical property after curing, simple preparation method and low cost.

The invention provides a polyacrylic acid inverse emulsion thickener and a preparation method thereof. The polyacrylic inverse emulsion thickener is prepared from the following components in parts by mass: 1 to 10 parts of modified attapulgite, 0.1 to 5 parts of hyperbranched acrylate, 30 to 60 parts of acrylic acid, 1 to 5 parts of a hydrophobic long-chain acrylate monomer, 5 to 20 parts of solvent oil, 0.5 to 5 parts of an emulsifier, 0.01 to 1 part of an initiator and 0.5 to 2.5 parts of a phase inversion agent. The preparation method comprises the following steps: firstly, introducing an isocyanate chain segment and a double-bond active group to the surface of acid-activated attapulgite to improve dispersity and reaction activity; then trimethylolpropane is used as a core, hyperbranched acrylate with multiple double bonds and a hyperbranched structure is constructed, and then the polyacrylic acid inverse emulsion thickener is prepared through an inverse emulsion method. Through the synergistic effect of the hyperbranched acrylate, the modified attapulgite and the hydrophobic long-chain monomer, the thickening performance, the electrolyte resistance and the long-term stability are remarkably improved.

Pavement aging can be reduced by applying to an asphalt-containing pavement a topcoat layer or a surface treatment containing asphalt binder emulsion with sterols.

The invention discloses Pickering emulsion applied to concrete demolding and a preparation method thereof, and relates to the technical field of building materials. The Pickering emulsion is prepared from the following raw material components: 200 to 600 parts of base oil, 50 to 60 parts of a compound emulsifier, 50 to 60 parts of a co-emulsifier, 1 to 2 parts of a dispersed phase pour point depressing component, 0.5 to 1 part of an antioxidant, 8 to 10 parts of a continuous phase thixotropic stabilizing component, 10 to 15 parts of a color regulating agent and 500 to 550 parts of water. The Pickering emulsion has excellent concrete demoulding performance, also has concrete self-curing performance and anti-ultraviolet performance, and can effectively improve the structural strength of concrete, prolong the service life of concrete and ensure the appearance quality of concrete. The problems existing in a traditional release agent are solved, additional functionality and attractiveness are provided for concrete products, and the release agent is suitable for various building and infrastructure projects and has wide application prospects.

The invention discloses a water-in-oil emulsion, a preparation method, application, a membrane and a cosmetic product containing the same. The water-in-oil emulsion is prepared from the following components in parts by weight: 0.25 to 50.00 parts of water phase, 0.45 to 80.00 parts of oil phase, 0.025 to 5.00 parts of emulsifier, 1 part of sterol and / or sterol derivative, 0.01 to 30.0 parts of powder and 0 to 3 parts of polymer. The water-in-oil emulsion disclosed by the invention can form a liquid crystal structure which is regularly and orderly arranged in space according to a certain direction, has low film forming continuity, hydrophobicity, flexibility of a wax film and excellent air permeability, and also has certain migration resistance of a high-molecular polymer film, but the brittleness is improved. In addition, the brittleness of a layer of uniform and continuous three-dimensional network structure film formed on the skin by the polymer can be improved, and the flexibility and uniformity are improved.

According to the emulsion mixing equipment applied to the mixing field and used for aluminum oxide composite fiberboard production, through a guide cylinder which forms an annular gap with the inner wall of a tank body in an enclosing mode and a stirring assembly arranged on the lower portion of the guide cylinder, raw materials circularly flow between the annular gap and an inner cavity of the guide cylinder, and the stirring assembly and a shearing assembly act synergistically; firstly, raw materials fully flow, components are promoted to be uniformly dispersed, local concentration difference is avoided, a foundation is laid for stable emulsification, agglomeration and precipitation are reduced, the emulsification efficiency and quality are improved, meanwhile, by means of a plurality of heat exchange structures such as a tank shell wall cooling clamping cavity, a spiral heat exchange pipe, an emulsification stator inner heat exchange channel and a guide cylinder shell wall spiral channel, sufficient heat exchange is achieved, and the emulsification efficiency and quality are improved. The raw material temperature is effectively controlled, heat accumulation and overheating are reduced, and the gelation probability is reduced.

The invention discloses a water-based acrylate pressure-sensitive adhesive emulsion as well as a preparation method and application thereof, and the preparation method comprises the following steps: S1, providing an acrylate pre-emulsion A and an initiator solution B; s2, dropwise adding a part of the acrylate pre-emulsion A into the initiator solution B, and carrying out a heating reaction to obtain a polymer A emulsion; s3, providing a monomer composition B, and mixing the rest of the acrylate pre-emulsion A and the monomer composition B to obtain an acrylate pre-emulsion B; and S4, dropwise adding the acrylate pre-emulsion B into the polymer A emulsion, and heating for reaction to obtain the water-based acrylate pressure-sensitive adhesive emulsion. The water-based acrylate pressure-sensitive adhesive emulsion prepared by the preparation method disclosed by the invention has relatively good adhesiveness, mobility and PVC shrinkage resistance after being coated on a PVC base material.

The invention belongs to the technical field of food processing of pectin, and discloses limonin-pectin emulsion gel with anti-inflammatory and intestinal probiotic functions as well as preparation and application of the limonin-pectin emulsion gel. The method comprises the following steps: 1) dissolving pectin with the esterification degree of 10-40% and the RGI proportion of 20-40% in water to obtain a pectin solution; adjusting the pH value to 3-6, adding a calcium ion solution, and shearing to obtain pectin sol; 2) dissolving limonin in the oil phase to obtain an oil phase containing limonin; and adding the oil phase containing the limonin into the pectin sol, carrying out shearing treatment, and standing to obtain the pectin emulsion gel loaded with the limonin. The emulsion gel provided by the invention can be independently used as an emulsifier, can stably load limonin, and realizes relatively high embedding efficiency. The emulsion gel disclosed by the invention can be used for remarkably regulating intestinal flora and increasing the content of short-chain fatty acid, and has remarkable anti-inflammatory and prebiotic activity. The emulsion gel provided by the invention is used for anti-inflammatory and intestinal probiotic functional products.

The invention relates to the technical field of waterproof materials, and particularly discloses a high-elasticity waterproof emulsion and a preparation method thereof. The invention discloses a high-elasticity waterproof emulsion. The water-based paint is prepared from the following raw materials in parts by mass: 40 to 60 parts of modified acrylic resin emulsion, 25 to 40 parts of waterborne polyurethane, 3 to 6 parts of hydroxyethyl methylacrylate, 0.5 to 1 part of mercaptopropionic acid, 6 to 8 parts of fluorinated mica sheet, 3 to 6 parts of organic silicon emulsion, 2 to 4 parts of fluorocarbon surfactant, 0.8 to 1.5 parts of adipic dihydrazide, 0.3 to 0.8 part of dynamic cross-linking agent, 3 to 8 parts of compatilizer, 0.5 to 1 part of antioxidant, 0.5 to 1 part of anti-aging agent, 0.5 to 1.5 parts of defoaming agent and 40 to 55 parts of solvent. The modified acrylic resin emulsion is prepared from a monomer comprising diacetone acrylamide. The high-elasticity waterproof emulsion prepared by the invention has relatively good elasticity, waterproof performance and aging resistance.

The invention provides an emulsion slow crosslinking type plugging control gel, which is in an oil-in-water type, and is prepared from the following raw materials in percentage by weight: 25 to 40 weight percent of nonionic monomer, 0.5 to 2 weight percent of dihydroxy anthraquinone, 5 to 16 weight percent of anionic monomer, 0.002 to 0.2 weight percent of initiator and the balance of water. The emulsion comprises the following components in percentage by weight: 10 to 35 percent of deionized water, 15 to 30 percent of non-polar solvent, 2 to 8 percent of emulsifier, 1 to 4 percent of emulsifying aid and 0.5 to 1.5 percent of phase inversion agent. According to the plugging adjusting gel, the modified functional monomer dihydroxy anthraquinone is added, and the dihydroxy anthraquinone and monomers such as acrylamide are copolymerized to form oil-in-water type polymer gel, so that the initial viscosity is low, the strength and the plugging rate are high, and the gelling time is controllable.

The additive 50 is used alone as a tablet or capsule, or together with a base product 54, to produce an enhancing product 52 that provides a health benefit 34 to a person 20 ingesting or using the additive 50, the additive 50 including an enzyme that stimulates the naturally occurring in the human body. The additive 50 has one or more hydrogenated substances 58, such as erythritol 58a, xylitol 58b, hydrogenated dihydromyricetin 58c and / or quercetin dihydrate 58d, and a flavonoid dihydromyricetin 14a. The flavonoid 14 may be extracted from Ampelopsis grossedentata plant 17 and / or a plant 16 selected from the genus Hovenia (e.g., Japanese raisin tree). The additive may also have one or more solvents 60, such as a bicarbonate compound 60a or an alcohol solvent 60b, a pH balanced acid 62, and / or a preservative 64. The base product 54 may be a liquid 66, a solid 68, a powder 70, a chew 72, a medicament 74, a cosmetic 76, or an emulsion or other coating product 78. The reinforced product 52 is a base product 54 reinforced by an additive.

The invention belongs to the technical field of nano materials, and relates to a high-content baicalin nano-emulsion as well as a preparation method and application thereof. The high-content baicalin nano-emulsion is prepared from the following raw materials in percentage by weight. 1%-40% of a radix scutellariae extract; 1%-30% of an emulsifier; 1%-20% of a co-emulsifier; 1%-30% of grease; 0.1%-1% of a preservative; and the balance of water. The O / W baicalin nanoemulsion (with the baicalin content of 1%-15%) prepared by adopting a homogenization-ultrasonic process has the average particle size of 50 nm-100 nm, is good in stability and low in viscosity, is a brown-yellow semitransparent liquid in appearance, and successfully solves the problems of poor water solubility and low bioavailability of baicalin. Compared with the prior art, the high-content baicalin nanoemulsion prepared by the preparation method disclosed by the invention has the advantages that the solubility of the baicalin is remarkably improved, the high-concentration baicalin stably exists in the nanoemulsion, and the high-content baicalin nanoemulsion can be applied to cosmetics and also can be used in medicines for treating skin diseases.