68 results about "Lipopeptide" patented technology

A lipopeptide is a molecule consisting of a lipid connected to a peptide. Bacteria express these molecules. They are able to self-assemble into different structures. Certain lipopeptides are used as antibiotics. Other lipopeptides are toll-like receptor agonists. Lipoproteins are self-assembling molecules that are able to form structures. Certain lipopeptides can have strong antifungal and hemolytic activities. It has been demonstrated that their activity is generally linked to interactions with the plasma membrane, and sterol components of the plasma membrane could play a major role in this interaction. It is a general trend that adding a lipid group of a certain length (typically C10–C12) to a lipopeptide will increase its bactericidal activity. Lipopeptides with a higher amount of carbon atoms, for example 14 or 16, in its lipid tail will typically have antibacterial activity as well as anti-fugal activity.