2046 results about "Hemostasis" patented technology

The invention relates to a battle wound field real-time hemostasis method based on a biological information sensing technology, and the technical scheme comprises the steps: introducing a time sequence biological signal for modeling, and carrying out the dynamic prediction of a battle wound state; on the basis of a biosensor data flow, a multi-dimensional time sequence state space is constructed, and the multi-dimensional time sequence state space comprises a nonlinear change trend of a bleeding rate, an evolution mode of tissue physiological parameters and a dynamic evolution process of a blood coagulation process; external intervention requirements are minimized while a hemostasis strategy is dynamically adjusted through active learning; defining multi-objective optimization modeling of key objectives of hemostasis efficiency, tissue damage minimization and pressure adaptability; estimating distribution prediction of success probabilities of different hemostasis strategies; the intelligent response mechanism is composed of a nanoscale blood coagulation factor carrier and a phase change regulation and control network. An environment triggering response model is constructed, and the blood coagulation factor carrier selectively releases blood coagulation factors according to biological signals including the pH value, the temperature and the bleeding rate.

The invention relates to injectable hydrogel for rapid hemostasis and antibiosis of an oral cavity as well as a preparation method and application of the injectable hydrogel, and the injectable hydrogel comprises the following components in percentage by weight: 5-15% of aminated chondroitin sulfate, 5-15% of oxidized dextran, 1-3% of platelet-rich fibrin and 0.5-1% of quercetin modified zeolite imidazole acid framework nanoparticles. According to the invention, Chs-ADH and ODex are adopted as matrix materials, PRF and ZIF-8 (at) QCT are introduced, the hydrogel is endowed with antibacterial, anti-oxidation and immunoregulation functions, and by optimizing the proportion of the components, the obtained hydrogel has good injectability, stability and degradation resistance, so that the hydrogel can still maintain an effective blood coagulation function in a high-humidity and high-enzymatic-activity oral environment.

The invention discloses a femoral artery paracentesis post-operation pressure-controlled hemostasis device and a monitoring intelligent control system thereof, and relates to the technical field of medical apparatuses and instruments, and the femoral artery paracentesis post-operation pressure-controlled hemostasis device comprises an assembly panel; the air bags are arranged at the bottom of the assembly panel; the air pump is arranged at the top of the assembly panel and used for controlling the air bags to contract; the control piece is arranged at the top of the assembly panel and used for controlling the air pump; the Doppler probe is arranged at the bottom of the assembly panel and used for detecting the blood flow speed of the far end of a puncture point, the hemostasis safety and efficiency are remarkably improved through multi-mode intelligent control and a real-time feedback mechanism, the vein area is accurately recognized and avoided in combination with ultrasonic and infrared spectrum analysis of the artery positioning module, the thrombus forming probability is effectively reduced, and the blood flow speed of the far end of the puncture point is detected. The pressure-time optimization model dynamically shortens the compression time (target 3 hours) based on the real-time hemostatic effect, and improves the comfort of the patient while ensuring the hemostatic effect.

The invention belongs to the technical field of medical instruments, and particularly relates to a postoperative hemostasis nursing device for thoracic surgery rehabilitation, which comprises a nursing box and a plastic cushion block arranged on one side of the nursing box, a controller is mounted on the side wall of the nursing box, a detachable gauze pad is mounted at the bottom of the plastic cushion block, and the postoperative hemostasis nursing device further comprises a pressure cylinder, a pressure cylinder is fixedly connected to the side wall of one side of the plastic cushion block in an inserted mode, a movable piston is arranged in the pressure cylinder in a sliding mode, and a supporting spring is fixedly arranged between the movable piston and the inner wall of the pressure cylinder; the connecting block is arranged on one side of the pressure cylinder, and the connecting block and the moving piston are jointly provided with a tension detection mechanism. According to the device, the binding force on the incision of a patient can be automatically adjusted, the situation that the pressure borne by the incision is increased due to breathing of the patient is avoided, cold compress compression can be continuously conducted on the incision, wound healing is promoted, meanwhile, continuous disinfection and bacteriostasis treatment can be conducted on the periphery of the incision, and the protection effect on the incision is good.

A device may include a flexible tube comprising: a distal end, a proximal tip, the proximal tip comprising a suction line extension being configured for placement in a uterine cavity of a uterus after childbirth, a tube center of the flexible tube; and at least one lumen around the tube center, the at least one lumen comprising a suction line, the suction line being in communication with a source of negative pressure and the suction line extension, the suction line extension being configured for applying the negative pressure to the uterine cavity using the source of the negative pressure thereby causing mechanical hemostasis of bleeding blood vessels of a uterine wall of the uterine cavity. Embodiments include an anchoring mechanism being proximate to the suction line extension along the flexible tube, the anchoring mechanism being configured for maintaining the suction line extension in a desired position within the uterine cavity.

The invention discloses a whole-process vascular interventional operation training method and system based on a virtual reality technology, and the method comprises the steps: firstly, developing a vascular interventional mechanics and collision simulation module, and achieving the deformation simulation of a blood vessel and a guide wire through the combination of position dynamics, a region shape matching technology and a Cosseerat elastic rod model, the collision between the blood vessel and the guide wire is treated by adopting a wide-to-narrow three-layer progressive collision detection method; secondly, constructing an immersive virtual operation scene through model construction and rendering optimization; visual angle roaming, instrument operation and interface interaction are fused, and multi-mode interaction control driving intervention training is achieved; finally, based on a'module-event 'dual-drive framework, operation tasks such as anesthesia, puncture, radiography, intervention, stent release and hemostasis are sequentially connected in series through a unified state machine, and whole-process training is achieved. The accuracy and stability of blood vessel and guide wire simulation are improved, the training immersion sense is enhanced, interventional operation whole-process training is achieved, and high teaching and practical value is achieved.

The invention discloses a method for preparing a methylacryloyl chitosan / gelatin-based hydrogel wound dressing through 3D printing and application, and relates to a method for preparing a hydrogel wound dressing and application. The problems that existing MXene is high in photo-thermal conversion temperature, and bacteria rapidly breed again after near-infrared irradiation is closed are solved. The ZGC composite hydrogel wound dressing integrates multiple functions, can simultaneously realize hemostasis, antibiosis, anti-inflammation, vascularization promotion and cell regeneration, and is especially suitable for infectious wounds. The antibacterial performance can be achieved under the activation of near-infrared light through the dual effects of a photothermal therapy and a photodynamic therapy, and meanwhile, the antibacterial effect can be achieved in cooperation with Zn < 2 + >. The ZGC composite hydrogel wound dressing can be accurately customized and printed through a 3D printing technology according to the shape and depth of a wound, the composite dressing can achieve accurate low-temperature photo-thermal treatment, meanwhile, the continuous release of Zn < 2 + > and the physical antibacterial function of MXene are maintained, normal tissue is protected while bacteria are killed, and the healing rate of an infected wound is remarkably increased.

The invention belongs to the technical field of radial artery compression haemostat, and relates to an intelligent control system and method for a radial artery compression haemostat, and the method comprises the steps: determining the adaptive initial pressure of the radial artery compression haemostat for a target patient through combining the individual medical representation angle and historical experience reference angle of the target patient; the initial hemostasis effect of the radial artery compression hemostat on the target patient is evaluated, the adaptive initial pressure is continuously corrected until the initial hemostasis effect reaches the expectation, and then the hemostasis condition of the target patient is monitored in real time to judge whether the preset decompression decision condition is met or not; the method comprises the following steps: executing pressure reduction operation of the radial artery compression hemostat, evaluating and feeding back the pressure reduction operation reasonability of the radial artery compression hemostat for a target patient, and executing wearing release prompt operation of the radial artery compression hemostat when the pressure balance state of the radial artery compression hemostat lasts for a preset duration. And highly intelligent and personalized management of the radial artery compression hemostat is realized.

A postpartum hemorrhage mitigation apparatus configured to be disposed at least partially within a uterine cavity of a uterus comprises a suction line, a suction line extension, a spiral slit, and an anchoring mechanism. The suction line has a distal portion that connects to a source of negative pressure. The suction line extension, which is disposed at a proximal portion of the suction line, is configured for placement in the uterine cavity after childbirth. The spiral slit in the suction line extension is configured for drawing blood and other bodily fluids into the suction line extension from the uterus. The spiral slit comprises a continuous cut through the suction line extension made in a spiral pattern extending along the length of the suction line extension. The anchoring mechanism maintains the suction line extension in a desired position within the uterine cavity.

A device for treating tissue includes a capsule extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, the capsule releasably coupled to a proximal portion of the device and clip jaws, proximal ends of which are slidably received within the channel of the capsule so that the clip jaws are movable between an open configuration and a closed configuration. Clip jaws are configured so that a distance between the distal ends of the clip jaws in an open configuration is between 15 and 18 millimeters. Clip jaws further include barbs extending from a distal portion thereof.

The invention is directed to a hemostasis therapeutic compression system including an apparatus and system to stop bleeding and assist recovery at a wound location. The hemostasis therapeutic compression apparatus includes a bladder having a transparent portion to visualize the bleeding wound location as well as having one side with an interface pressure sufficient to stop bleeding at the wound site, and the wrap has as an elongated tab as part of a hook and loop portion for self-application by the user or patient. The hemostasis therapeutic compression apparatus includes compression not just on the bleeding wound site but alongside the site for increased and faster recovery and less complications. The transparent portion of the bladder may be in the shape of a circle, oval, kidney, elongated kidney, square, rectangle, "U", "C", and other known shapes depending on the size and location of the bleeding wound site on the limb.

The invention relates to the technical field of nano materials and biological medicines, in particular to application of structurally reversible gel in preparation of a physical blood coagulation material, the structurally reversible gel comprises loosely assembled nanorod assemblies and a solution for dispersing the loosely assembled nanorod assemblies; the nanorod assembly comprises an inorganic one-dimensional nanorod and anions capable of participating in the assembly of the inorganic one-dimensional nanorod; the inorganic one-dimensional nanorod at least contains rare earth metal elements. The physical blood coagulation material simulates the assembly process of fibrin, shows excellent hemostasis capability independent of natural hemostasis, reduces the blood coagulation factor level, and effectively avoids the thrombus risk caused by excessive blood coagulation. In addition, the material is simple and stable in component, low in preparation cost, high in safety and capable of being stored and used for a long time.

The invention discloses an oral care composition containing ampelopsis japonica polysaccharide and application of the oral care composition in inhibiting gingival bleeding. The oral care composition comprises ampelopsis japonica polysaccharide and an orally acceptable carrier, wherein the pH (Potential of Hydrogen) range of the oral care composition is 5.9 to 7.7. The invention also discloses an application of the ampelopsis japonica polysaccharide in the oral care composition for inhibiting gingival bleeding. The invention discloses application of silicon dioxide with a high oil absorption value in an oral care composition for improving the gingival bleeding inhibiting effect of ampelopsis japonica polysaccharide. The combination of the high-oil-absorption-value silicon dioxide and the low-oil-absorption-value silicon dioxide is applied to the oral care composition for improving the gingival bleeding inhibiting effect of the ampelopsis japonica polysaccharide; the invention further discloses application of sorbitol in the oral care composition for improving the effect of inhibiting gingival bleeding by the ampelopsis japonica polysaccharide. The oral care composition has a hemostatic effect and can effectively solve the problem of gingival bleeding.

The invention relates to the technical field of hemostasis, and discloses a hemostasis device which comprises a tourniquet, a device bin is installed on the tourniquet, a winding shaft is installed in the device bin, two elastic belts are installed on the winding shaft, the ends of the two elastic belts are fixedly connected with the inner walls of the two ends of the tourniquet respectively, and a guide cylinder is fixedly installed on the winding shaft. According to the hemostasis device, the mechanical timing device is used for driving the rotating cylinder to wind the elastic rope, the first magnetic ring is attracted by the magnetic force of the second magnetic ring to drive one end of the elastic rope to move upwards in the rotary knob, and when the rotating shaft and the rotating cylinder are not reset completely, the elastic rope is pulled, so that the elastic rope is wound, and the hemostasis effect is achieved. When the elastic rope is stretched to a certain degree, the pulling force borne by the first magnetic ring is larger than the magnetic attraction force exerted on the first magnetic ring by the second magnetic ring, the first magnetic ring is downwards aligned with the magnetic shaft, the magnetic shaft retracts into the rotary knob, the rotary knob moves upwards to reset, the elastic belt is not rolled any more, and the relaxation time of the tourniquet is effectively adjusted according to the limb bleeding degree of a patient.

The utility model discloses a detachable blood vessel closer, which relates to the technical field of medical instruments and comprises a mounting plate and a mounting component, a quick mounting groove is formed in the middle of the mounting plate, and the mounting component which is used for quick mounting and convenient to detach is arranged in the quick mounting groove. The mounting assembly comprises a side mounting groove, a quick mounting block, an internal thread barrel, a hemostasis plate and a mounting cap, the quick mounting block is mounted in the side mounting groove in a clamped mode, the side edge of the quick mounting block is connected with the internal thread barrel, the hemostasis plate is mounted in the internal thread barrel, the mounting cap is arranged at the top of the hemostasis plate, and a limiting rod is mounted at the end of the interior of the side mounting groove. According to the detachable blood vessel closer, the quick mounting groove is used for quick mounting of the mounting assembly for blood vessel compression hemostasis, the quick mounting block is slidably mounted into the side mounting groove, operation is easy and convenient, the internal thread barrel is used for mounting the hemostasis plate, the position of the hemostasis plate in the internal thread barrel can be adjusted through rotation of the hemostasis plate, the compression hemostasis strength is adjusted, and the hemostasis effect is improved. The operation is simple.

The invention provides a device for achieving brachial artery compression hemostasis, and relates to the technical field of medical instruments.The device for achieving brachial artery compression hemostasis comprises a wearing assembly suitable for being bound to the upper arm of the human body and achieving device wearing; the pressure applying unit array assembly is arranged on the wearing assembly and is used for carrying out compression operation on a puncture point area on the upper arm of the human body; the distributed pressure sensing assembly is arranged on the wearing assembly, located on the outer side of the pressure applying unit array assembly and used for sensing contact pressure information of the pressure applying unit array assembly and the puncture point area; and the controller is used for regulating and controlling the compression operation based on the dynamic pressure distribution represented by the contact pressure information so as to maintain effective compression on the puncture point. According to the technical scheme, compression failure caused by slight change of the posture of the upper limbs of the patient can be effectively reduced.

The invention relates to the technical field of data processing, in particular to an intelligent wrist type hemostasis device and a control method thereof. The method comprises the following steps: controlling the intelligent wrist hemostasis device to start pressurizing, and collecting a PPG signal of a user; recording a pressure value when the PPG signal disappears or the waveform amplitude of the PPG signal is reduced to a target threshold value; determining initial target pressure according to the pressure value; controlling the intelligent wrist hemostasis device to reach target pressure, and collecting physiological data of the user under the target pressure; inputting the physiological data into a trained risk early warning model to obtain a risk coefficient and a risk type; if the physiological data meet the preset pressure reduction condition, step-type pressure reduction is carried out; in the maintaining stage of the stepped pressure reduction, if the risk coefficient is larger than or equal to a second threshold value, the intelligent wrist type hemostasis device is controlled to return to the target pressure before pressure reduction, early warning is triggered, and the compression time is prolonged. According to the method, the hemostatic effect and safety can be improved.

The invention discloses a cranial cavity rapid hemostasis instrument which comprises a sleeve, a conductive expansion and contraction piece and a push-pull rod connected with the conductive expansion and contraction piece, a through penetrating hole is formed in the sleeve, the push-pull rod can drive the conductive expansion and contraction piece to move in the penetrating hole, and the conductive expansion and contraction piece is electrically connected with an external power source through the push-pull rod. The conductive expansion and contraction piece is of a net-shaped structure, the conductive expansion and contraction piece can be contracted into a strip shape in the penetrating hole, the conductive expansion and contraction piece can be expanded into a sphere-like shape outside the penetrating hole, the conductive expansion and contraction piece comprises a plurality of first silk threads and a plurality of second silk threads, and the extending directions of the first silk threads and the second silk threads are arranged in a staggered mode. The first silk threads and the second silk threads are made of flexible conductive materials. According to the invention, medium injection is not needed, the expansion speed is high, the hemostasis efficiency is high, and the pressure distribution is uniform.

The invention relates to the technical field of medical instruments, and discloses an adjustable femoral artery automatic pressurizing device which comprises a main shell, a position adjusting assembly is mounted at the top of the main shell, a moving shell is slidably connected to the middle of the main shell, a connecting column is fixedly connected to the bottom of the moving shell, an air bag is arranged at the bottom of the connecting column, and an air outlet is formed in the middle of the air bag. A compression head is fixedly connected to the bottom of the air bag, an angle adjusting and positioning assembly is installed on the side face of the main shell, a bandage rod is arranged on the side face of the angle adjusting and positioning assembly, a composite sensing module is installed in the middle of the compression head, and an air pipe is arranged in the movable shell. One end of the air pipe penetrates through the connecting column and is fixedly connected to the air hole of the air bag. By sensing physiological signals formed by blood flow and hematoma in real time, self-adaptive closed-loop adjustment of compression pressure is realized, so that hemostasis accuracy, individualized level and safety of the automatic femoral artery pressurizing device are improved.

Devices, systems, and methods for sealing medical devices, particularly during intravascular access, are disclosed herein. Some aspects relate to a hemostatic valve for sealing a wide range of medical devices, such as catheters, wires, embolectomy systems. The valve can include an elongate member having a first end, a second end, and a central lumen extending therebetween. A reinforcement structure extends along at least a portion of the elongate member and is coupled to the elongate member. A shell defining a first aperture and a second aperture may be included, which first and second apertures can be fluidly coupled by the elongate member. A tensioning mechanism is coupled to the shell and to the elongate member, the tensioning mechanism can be moveable between a first configuration wherein the tensioning mechanism is collapsed and the central lumen is sealed and a second configuration wherein the central lumen is open.

The present invention provides a carotid artery pressurized hemostasis device for head and neck surgery, which belongs to the field of medical device technology. The device includes an adjustment mechanism, an arc-shaped rail is fixedly installed on the top of the adjustment mechanism, and a hemostasis device is movably installed on the inner side of the arc-shaped rail; the hemostasis device includes an arc-shaped block and a mounting hole. The hemostasis device of the present invention has significant advantages. During use, medical staff can conveniently adjust the angle and position of the hemostasis device according to the patient's wound condition. By rotating the second handle, the screw rod drives the slide, so that the hemostasis mechanism moves down smoothly to contact the wound. When pressure is applied, the buffer spring plays a role, effectively avoiding excessive pressure on the patient's neck, ensuring safe and comfortable operation. At the same time, the bottom plate moves up to squeeze the elastic water bag, and the water flows into the elastic hemostasis bag. As the slide moves further down, the elastic hemostasis bag expands and cooperates with the hemostasis plate, greatly improving the efficiency and accuracy of hemostasis, and providing strong protection for the treatment of patients.

The invention relates to the technical field of medical instruments, in particular to an acute bleeding emergency device for interventional catheter room nursing, which comprises a shell and a binding component, a hemostasis component is arranged in the shell, the bottom of the shell is detachably connected with a Doppler probe, the Doppler probe is in signal connection with a control system, and a pressure detection component is further arranged at the bottom of the shell. The hemostasis assembly comprises a first air bag filled with gas, the outer top wall of the first air bag is fixedly connected with the inner top wall of the shell, an expansion layer is arranged at the bottom of the first air bag and has the characteristics of water absorption expansion and expansion cooling, and a plurality of temperature change springs are arranged in the first air bag. A hemostasis mechanism which replaces traditional monitoring signal response with mechanical response is designed, and the subsequent hemostasis condition of a patient is detected, so that the hemostasis compression acting force of the patient is adjusted, rapid and accurate hemostasis operation is achieved, and the comfort of the patient is improved while the hemostasis efficiency and safety are improved.

The utility model discloses a closing clip capable of preventing tissue from being torn, and belongs to the field of medical hemostatic clips. The closing clamp capable of preventing the tissue from being torn comprises a first clamping arm and a second clamping arm, the near ends of the first clamping arm and the second clamping arm are connected through a connecting part, and the far end of the first clamping arm and the far end of the second clamping arm are respectively provided with a locking structure which can be buckled and locked together. The clamping faces of the first clamping arm and the second clamping arm are each divided into an anti-skid tooth face and a clamping smooth face in the width direction, and the anti-skid tooth face and the clamping smooth face of the first clamping arm and the anti-skid tooth face and the clamping smooth face of the second clamping arm are arranged in a one-to-one correspondence mode or in a crossed correspondence mode. According to the utility model, the clamping surfaces of the two clamping arms of the closing clamp are divided into the anti-slip tooth surfaces and the clamping smooth surfaces, so that the clamping pressure of the closing clamp on vascular tissues during closing is reduced, unnecessary damage to the tissues in the process of closing the tissues is effectively avoided, and hemostasis failure caused by tearing of the vascular tissues is prevented.

The invention relates to the technical field of compression hemostasis in interventional operations, and particularly discloses an adjustable compression hemostasis fixing band for interventional operations, which comprises a compression hemostasis component and a fixing component, the compression hemostasis component comprises a mounting bag and a sandbag, an interlayer bag is arranged in the mounting bag, and first magic tapes are arranged on the upper and lower inner walls of openings at two ends of the mounting bag; the fixing assembly comprises a first elastic compression tourniquet, a second elastic compression tourniquet and elastic viscous fixing bands, the mounting bag is fixedly connected to the first elastic compression tourniquet, and the elastic viscous fixing bands are connected to openings in the two ends of the mounting bag; the first elastic compression tourniquet, the second elastic compression tourniquet and the elastic viscous fixing band are fixed to the thigh of the affected side of a patient and the paracentesis incision in a reinforced mode, and through stable fixation at multiple positions, the device is not prone to sliding and has no harm to the skin, and the comfort level of the patient is improved.

A novel strategy for wound healing involving the coating of oxygen nanobubbles with exosomes and incorporating them into a polyvinyl alcohol (PVA) / gelatin hybrid hydrogel. In this work, we not only mitigate wound hypoxia but importantly have an efficient delivery method of exosomal nanoparticles, which to date has been confounded by very low to lack of uptake by cells in hypoxia. Furthermore, the self-healing properties of the hydrogel, along with its gelatin component, aids in hemostasis, thereby benefiting acute and surgical wound healing. Additionally, the crosslinking bonds within the hydrogel facilitate the decomposition of hydrogen peroxide (H2O2), alleviating wound inflammation. The multifunctional hydrogel provides for enhanced wound healing through increased angiogenesis, enhanced exosome delivery, hypoxia mitigation, and inflammation inhibition.

The invention relates to the technical field of hemostasis devices, in particular to a rapid wound hemostasis device which comprises a binding belt, the binding belt is used for binding limbs of a person, an inflatable cavity and a first pressure sensor are arranged in the binding belt, and the first pressure sensor is installed in the inflatable cavity. The pressure monitoring device comprises an inflatable cavity used for monitoring pressure data in the inflatable cavity and a pressure adjusting assembly, the pressure adjusting assembly adjusts the pressure of gas in the inflatable cavity by inflating the interior of the inflatable cavity and exhausting the gas in the inflatable cavity, and hemostasis of a wound is achieved through an inflatable binding belt of the pressure adjusting assembly. And the bundling pressure can be adjusted through the first pressure sensor, the main control device and the pressure adjusting device, meanwhile, the bundling time can be monitored, and the effects of unbundling and re-bundling of the limbs are automatically achieved.

A device for treating tissue includes a capsule extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, the capsule releasably coupled to a proximal portion of the device and clip jaws, proximal ends of which are slidably received within the channel of the capsule so that the clip jaws are movable between an open configuration and a closed configuration. Clip jaws are configured so that a distance between the distal ends of the clip jaws in an open configuration is between 15 and 18 millimeters. Clip jaws further include barbs extending from a distal portion thereof.

The invention belongs to the technical field of radial artery compression hemostats, and particularly relates to a radial artery hemostasis method based on real-time pulse analysis and a hemostat control system. A slow and continuously changing force is applied to a radial artery puncture opening through the pressure applying module, meanwhile, the pulse detection module transmits a pulse forced feedback signal of the puncture opening to the main control module in real time, and the main control module analyzes and processes the received feedback signal in real time and judges the current hemostatic state of the radial artery. And on this basis, the pressure applying module is controlled to adjust the pressure. The method is characterized in that the relation between pulse forced feedback signals and the forced state of the radial artery is obtained through clinical tests according to the difference of the pulse feedback signals of the radial artery in different pressed states, and therefore the pressure is stabilized in the state that the blood flow of the radial artery is stable and a puncture opening does not bleeding. According to the scheme, the individual difference between different patients can be overcome, the compression hemostasis strength is adjusted in a self-adaptive mode, and the occurrence rate of related complications such as radial artery occlusion is effectively reduced.

The invention belongs to the technical field of compression hemostasis devices, and particularly relates to a medical oncology postoperative femoral artery compression hemostasis nursing device which comprises a compression hemostat, and hemostatic cotton is arranged at the bottom of the compression hemostat; the compression hemostat is provided with an ejection mechanism, the ejection mechanism comprises a storage frame used for containing hemostatic cotton, and the compression hemostat is provided with a rotating mechanism used for driving the ejection mechanism and the hemostatic cotton to adjust the positions and a lifting mechanism arranged on the compression hemostat; by rotating the rotating disc, the positioning ball slides and resets under the action of the push plate and the elastic piece and is temporarily fixed in the positioning groove, so that the rotating disc drives the hemostatic cotton to rotate to a position matched with a wound. The rotating disc can be rotated at will through operation, then the rotating disc drives the hemostatic cotton to conduct position adjustment, then the position is adjusted to a proper angle, and targeted pressing hemostasis is conducted on a wound behind the femoral artery.

The invention provides a tissue adhesive as well as a preparation method and application thereof, the preparation method specifically comprises the following steps: by adopting a one-pot reaction method, blending and heating biological protein, reducing sugar, a polyphenol unit substance and metal chlorate for reaction to obtain a protein-reducing sugar tissue adhesive with a macromolecular network structure, after the protein-reducing sugar tissue adhesive is subjected to low-temperature incubation, dense and ordered hydrogen bonds are reconstructed in a network structure, and the tissue adhesive is obtained. According to the tissue adhesive provided by the technical scheme of the invention, the tissue adhesive has excellent adhesion characteristics through a synergistic effect of chain enhancement and physical acting force caused by Maillard chemical reaction performed by a one-pot cooking method, so that the tissue adhesive can have modulus and electroactivity matched with natural soft tissues; meanwhile, the hydrogel also has the characteristics of injectability, self-healing capability and quicker and stronger adhesion, can be effectively injected into a nerve injury part, realizes incompressible nerve hemostasis and seamless filling connection of a lesion cavity, and promotes nerve healing and regeneration.