11315 results about "Polysaccharide" patented technology

The invention provides a preparation method of a polygonatum sibiricum fermentation product, which comprises the following steps: A) pretreating a polygonatum sibiricum raw material, and mixing with water to obtain polygonatum sibiricum slurry; b) heating the polygonatum sibiricum slurry, mixing the heated polygonatum sibiricum slurry with a nitrogen source and a phosphorus source, and performing primary sterilization to obtain sterilized polygonatum sibiricum slurry; c) inoculating the sterilized rhizoma polygonati slurry with saccharomycetes, and fermenting to obtain fermentation liquor; d) adding a carbon source into the fermentation liquor, performing secondary sterilization, inoculating lactic acid bacteria, performing secondary fermentation, and performing third sterilization to obtain secondary fermentation liquor; and E) adding a compound enzyme into the secondary fermentation liquid for enzymolysis, then sterilizing for four times, and centrifuging to obtain the polygonatum sibiricum fermentation product. 3000 Da), a small molecule polypeptide (lt; the polygonatum kingianum fermentation product prepared by the method disclosed by the invention has the advantages that the conversion of polygonatum kingianum saponin can be promoted, the contents of diosgenin and trilliin are increased and calibrated, and the polygonatum kingianum fermentation product has the effects of improving the reaction capability and the exercise capability.

A fire retarding biochemical liquid composition including: a dispersing agent realized in the form of a major amount of water, for dispersing alkali metal ions dissolved in the water; a major amount of a first fire retarding agent realized in the form of a first alkali metal salt of a nonpolymeric saturated carboxylic acid, specifically, tripotassium citrate, for providing metal potassium ions dispersed in the water when the at least one alkali metal salt is dissolved in the water to form a mixed retardant solution; a minor amount of a second fire retarding agent realized in the form of a second alkali metal salt of a nonpolymeric saturated carboxylic acid, specifically, sodium benzoate (SB), for providing metal sodium ions dispersed in the water when the at least one alkali metal salt is dissolved in the mixed retardant solution, for functioning as a secondary fire retardant agent and also inhibiting surface corrosion reactions involving metals contacting the mixed retardant solution, including specific metals, namely 2024-T3 Aluminum, 4130 Steel, Yellow Brass, and Az31B Magnesium; a minor amount of thickening agent in the form of a biomolecular polymer consisting of polysaccharides, for increasing the viscosity of the mixed retardant liquid during application operations; a minor amount of coloring agent in the form of fugitive color dye powder, or non-fugitive pigment powder, for imparting a visible color (e.g. red or green) when the fire retarding biochemical liquid composition is applied to a surface to be protected against fire, as water molecules in the retardant liquid coating evaporate to the environment during drying, to form a thin fire retardant coating deposited on the treated surfaces having a characteristic visible color, and comprising potassium and sodium salt crystals mixed within the polysaccharides of the biomolecular polymer. Wet and dry concentration formulations of the fire retarding biochemical liquid composition are disclosed for use with both serial and ground delivery methods and apparatus.

The invention discloses a foam base fluid, a preparation method and a preparation method of a temperature-resistant and salt-resistant CO2 foam flooding system.The foam base fluid comprises a foaming agent, a foam stabilizer and water, the foaming agent is a betaine type surfactant, and the foam stabilizer is a biological polysaccharide polymer. A temperature-resistant and salt-resistant foam base solution and a biological polysaccharide reinforced CO2 foam oil displacement system are obtained by introducing a biological polysaccharide polymer as a foam stabilizer and combining with a betaine type surfactant, so that the problem that the viscosity of polyacrylamide as a traditional foam stabilizer is reduced and even fails in a high-temperature and high-salt environment is effectively solved; the stability of CO2 foam can be obviously improved. Meanwhile, the biological polysaccharide polymer has the characteristics of environmental friendliness and degradability, and can effectively reduce the negative influence on the environment. In addition, due to rich resources and low price of the biological polysaccharide, the system is competitive in cost, and the economic benefit of the oil field can be further improved.

The invention provides velvet antler mushroom sporocarp water extraction residue polysaccharide as well as an extraction method and application thereof, and belongs to the technical field of edible mushroom polysaccharide preparation. The invention provides an extraction method of water extraction residue polysaccharide of a mushroom fruiting body, which comprises the following steps: sequentially carrying out solid state fermentation, post-treatment and hot water extraction on the water extraction residue of the mushroom fruiting body to obtain an extraction product containing the water extraction residue polysaccharide of the mushroom fruiting body. According to the method disclosed by the invention, the water extraction residues of the pilose antler mushroom sporocarp are used as raw materials, so that high-value utilization of the water extraction residues of the pilose antler mushroom sporocarp can be realized. Moreover, the method can improve the yield and content of polysaccharide, and has the advantages of no chemical residue, ecological environmental protection, high production efficiency and the like. Besides, the polysaccharide prepared by the extraction method disclosed by the invention is stable under a digestion condition, and the prepared polysaccharide can improve the content of short-chain fatty acids in intestinal tracts, so that a basis is provided for application of the polysaccharide of the water-extracted residues of the fruiting bodies of the velvet antler mushrooms in new potential prebiotics.

The invention relates to a preparation method of a chlorella exosome as well as a product and application of the chlorella exosome, the preparation method comprises the following steps: (1) mixing extremely micro chlorella with a separation buffer solution, and then carrying out wall breaking treatment to obtain a cell breaking solution; (2) centrifuging the cell disruption liquid, and reserving supernate; and (3) filtering the supernate to obtain the chlorella exosome. The preparation method of the chlorella exosome, provided by the invention, is simple in steps and easy to operate, the chlorella raw material and the specific separation buffer solution are subjected to wall breaking treatment, so that active ingredients in the prepared chlorella can be better extracted, the content of protein and polysaccharide in the obtained exosome is higher, and the purity of the exosome is improved. Meanwhile, gradient centrifugation, filter membrane filtration and the like are assisted in the preparation process, so that the prepared exosome is high in purity and less in impurities.

The invention discloses thermophilic fungus cleavable polysaccharide monooxygenase and application thereof, and belongs to the technical field of enzyme engineering and microbial engineering. The thermophilic fungus lysing polysaccharide monooxygenase provided by the invention has excellent thermal stability; when the lysable polysaccharide monooxygenase is used for synergistically hydrolyzing phosphoric acid swelling cellulose, microcrystalline cellulose and bagasse, the enzymolysis rate is increased, and the problems of poor thermal stability of the lysable polysaccharide monooxygenase, low enzymolysis rate of synergic cellulase and high LPMOs enzyme dosage are solved. The method has high practicability and can be widely applied to the enzymolysis process of various cellulosic substrates, so that the enzymolysis efficiency of the cellulosic substrates is remarkably improved.

The invention relates to the technical field of cosmetic raw materials, in particular to a fibroin-active matter nano aggregate and a preparation method thereof.The preparation method of the fibroin-active matter nano aggregate is characterized by comprising the following steps that S1, a fibroin aggregate aqueous solution and large-molecular-weight active matter are obtained, mixing the fibroin aggregate aqueous solution and the high-molecular-weight active matter to obtain a first mixed solution; and S2, continuously stirring the first mixed solution for 2-240 minutes to obtain a target product, wherein the large-molecular-weight active matter comprises at least one of protein, polysaccharide, glycosaminoglycan, sugar alcohol and a compound of the protein, the polysaccharide, the glycosaminoglycan and the sugar alcohol, and the mass ratio of the silk fibroin aggregate in the silk fibroin aggregate water solution to the large-molecular-weight active matter is (100: 1)-(1: 2). The transdermal property of the active matter can be simply and effectively improved while the structure and the performance of the active matter are not changed.

The invention provides application of polygonatum cyrtonema polysaccharide in preparation of medicines for treating ulcerative colitis or reducing blood glucose. A main chain of a sugar chain structure of the homogeneous polysaccharide PCP2 in polygonatum cyrtonema is mainly composed of-> 1)-beta-D-Fur-(2->,-> 1, 6)-beta-D-Fur-(2-> and-> 6)-alpha-D-Glcp-(1-> and beta-D-Fur-(2->), a side chain is mainly composed of beta-D-Fur-(2-> and-> 2)-beta-D-Fur-(6-> at a C-6 position of-> 1, 6)-beta-D-Fur-(2->), Fur represents furanose, Glcp represents glucopyranose, Glcp represents glucopyranose, and Glcp represents glucopyranose. The novel polysaccharide compound can relieve intestinal injury of mice, increase expression of tight nectin and mucoprotein, relieve oxidative stress reaction, promote production of short-chain fatty acid and improve composition of intestinal flora, and can be applied to the field of medicine as a medicine for treating ulcerative colitis. Meanwhile, the homogeneous polysaccharide PCP2 in polygonatum cyrtonema can significantly inhibit the activity of alpha-amylase and alpha-glucosidase, can also promote the ability of insulin resistance 3T3-L1 fat cells to uptake and consume glucose, shows a significant hypoglycemic effect, and has a good development prospect in the aspect of preparation of hypoglycemic drugs.

The invention relates to the technical field of microorganisms, in particular to a viable bacterium preparation of a lactobacillus paracasei strain as well as a preparation method and application of the viable bacterium preparation. The viable bacterium preparation comprises a lactobacillus paracasei strain and auxiliary materials, and the preservation number of the lactobacillus paracasei strain is CGMCC (China General Microbiological Culture Collection Center) No.27974. The viable bacterium preparation can inhibit the growth of streptococcus mutans, reduce the formation of a dental plaque biofilm caused by the streptococcus mutans, reduce the content of a mature dental plaque biofilm, inhibit the level of water-insoluble exopolysaccharides generated by the streptococcus mutans, reduce the expression quantity of cariogenic genes gtfB, gtfC, gtfD, ftf and LuxS of the streptococcus mutans, improve the cariogenic activity of the streptococcus mutans and improve the cariogenic activity of the streptococcus mutans. The adhesion rate of streptococcus mutans on a hydroxyapatite tooth model is reduced, and a beneficial in-vitro probiotic function is achieved.

The invention discloses an immunoregulation hydrogel as well as a preparation method and application thereof, and relates to the technical field of medical materials, amino-derived cationic polysaccharide, carboxyl-derived anionic polysaccharide and dopa-modified protein biopolymer materials are used as biological matrix materials, spermidine is used as a bioactive functional component, and the immunoregulation hydrogel is prepared by a one-step method. The preparation method comprises the following steps: by taking a benzaldehyde-terminated high polymer material as a cross-linking agent, forming a first layer of dynamic reversible cross-linked network structure through Schiff base reaction; then calcium ions are introduced, and the calcium ions and carboxylate radicals are complexed and cross-linked to form a second layer of static irreversible cross-linked network structure which can be used for an ESD (Electro-Static Discharge) operation. By adopting a step-by-step cross-linking mode, the first-step cross-linked single-network hydrogel has injectability, self-repairability, tissue adhesiveness and an immune regulation function, and the second-step cross-linking further ensures stable and lasting performance, so that the problems that a submucosal injection material is easy to disperse, short in lasting time and poor in stability are solved. The immunoregulation function effect of the wound repair material is poor.

The invention discloses a protein-based hydrogel adsorption material and application thereof in repairing water and soil heavy metal pollution, polysaccharide is doped into protein hydrogel to prepare the hydrogel adsorption material which is good in toughness, high in porosity and rich in surface adsorption functional groups. The heavy metal contaminated water and soil can be effectively adsorbed and efficiently recycled, especially for the heavy metal contaminated soil, the heavy metal contaminated soil is coated with the heavy metal contaminated water and soil adsorbent, the heavy metal contaminated soil is covered with the heavy metal contaminated water and soil adsorbent, in-situ remediation of the contaminated soil is achieved, meanwhile, the thin film is removed after remediation, and the risk of secondary overflow is thoroughly avoided. Results show that the protein-based hydrogel adsorbing material can efficiently remove different heavy metal pollutants, and after different treatments, the corresponding agricultural soil land control level can be reached. Moreover, no nutrient loss is observed in the treated soil, and no secondary toxic product is generated, so that the method has relatively high sustainability and agricultural application feasibility.

The invention relates to the technical field of agricultural fertilizers, discloses a seaweed extract-functional microorganism compound slow-release fertilizer and a preparation method thereof, and solves the problems in the background art. The seaweed extract is a compound containing enteromorpha polysaccharide and alginic acid extract; the functional microorganism is a complex microbial inoculant composed of phosphate solubilizing bacteria, nitrogen-fixing bacteria, phosphate solubilizing bacteria and bacillus; the slow-release carrier is prepared by coating the seaweed extract and the functional microorganisms with sodium alginate-chitosan microcapsules; the signal molecule is selected from at least one of polyamine substances and jasmonic acid methyl ester; the fertilizer has the advantages that the utilization rate of the fertilizer can be increased, growth and reproduction of soil microorganisms are promoted, the stress resistance of crops is improved, and the requirements of different soil types and planting environments can be met.

The invention relates to a composition containing camellia nitidissima extract and capable of brightening skin color and application of the composition to preparation of cosmetics suitable for dry sensitive skin, and the composition comprises the following components: camellia nitidissima flower extract, elm bark extract, oat kernel protein and laver polysaccharide in front of water temple, the weight ratio of the camellia nitidissima flower extract to the elm barks extract to the oat kernel protein to the laver polysaccharide in front of water temple is (1-10): (1-8): (0.1-1): (0.01-0.1). The composition can achieve the optimal long-acting brightening, barrier repairing and stimulation relieving effects on the aspect of efficacy.

The invention discloses an environment-friendly slow release fertilizer and a preparation method thereof, and belongs to the technical field of fertilizer mixture preparation. The preparation method comprises the following steps: mixing and stirring a mussel extract-polysaccharide-nitrogen fertilizer complex, an inorganic fertilizer and water according to a weight part ratio of (1-2): (5-7): (15-23), heating to 50-60 DEG C to form a dispersion solution, mixing and stirring the dispersion solution and a calcium salt according to a weight part ratio of 1: (0.005-0.01), cooling to 20-25 DEG C, and reacting for 20-24 hours to obtain a viscous mixture; and drying, dewatering and crushing the viscous mixture to obtain the environment-friendly slow-release fertilizer. According to the environment-friendly slow-release fertilizer, the mussel extract with a good adhesion effect and the carboxymethyl cellulose or the hyaluronic acid with biocompatibility are used as carriers, through the synergistic cooperation of an amide structure, an imine structure and metal coordination, wrapping of a nitrogen fertilizer and an inorganic fertilizer is achieved, and finally the environment-friendly slow-release fertilizer is obtained.

The invention discloses a probiotic-polyphenol nanoparticle colon-targeted co-delivery system as well as a preparation method and application thereof, and belongs to the field of biological medicines. The FCPs and hyaluronic acid (HA) are combined through non-covalent interaction, so that the hydrogel has colon targeting property and mucosal adhesion at the same time, and delivery of probiotics is facilitated. The hydrogel (HF) based on polysaccharide has good biocompatibility, and can be used for effectively encapsulating the probiotics and the natural products. Then, the PDA-TH NPs and BA are incorporated into the polysaccharide chain network of HF, and finally the BA-HF-PDAT targeted co-delivery system is constructed. The BA (at) HF-PDAT targeted co-delivery system can protect BA from serious gastrointestinal stress, and is jointly assembled with PDT-TH NPs to realize dual slow release of thymol (Thy), so that the treatment effect of BA and Thy is improved, and the BA (at) HF-PDAT targeted co-delivery system contributes to treatment of clostridium difficile infection (CDI).

The invention discloses injectable hydrogel with redox activity and electroactivity as well as a preparation method and application of the injectable hydrogel, and belongs to the technical field of medical materials. The preparation method comprises the following steps: reacting methacrylic anhydride and polysaccharide molecules in a solvent to prepare a double-bond functional polymer; the preparation method comprises the following steps: firstly, pre-polymerizing dopamine in a solvent, and then adding MOF (Metal Organic Framework) to carry out polymerization reaction, so as to prepare dopamine modified MOF; reacting the dopamine modified MOF, EDOT and ferric salt in a solvent, and collecting the precipitate to prepare a nano filler; the preparation method comprises the following steps: jointly dispersing the double-bond functional polymer, active polypeptide, a photoinitiator and nano filler into a solvent, and carrying out photocuring cross-linking. The preparation condition is mild, gel forming is rapid, the method is simple, the prepared hydrogel has injectable performance and conductive performance, catalytic activity of natural enzyme can be simulated, active oxygen removal can be achieved in the early stage of myocardial ischemia, electrical conduction of infarction parts can be enhanced, and effective recovery of cardiac functions can be achieved.

The invention relates to the technical field of pharmaceutical chemicals, and discloses sequential drug release liposome hydrogel and a preparation method and application thereof, and the preparation method of the liposome hydrogel comprises the following steps: step 1, preparation of drug-loaded positive charge liposome; step 2, preparing phenylboronic acid modified polysaccharide; and step 3, carrying out vortex mixing on the drug-loaded positive charge liposome solution, the phenylboronic acid modified polysaccharide hydrogel precursor powder and the spermidine solution to obtain the liposome hydrogel. According to the sequential drug release liposome hydrogel as well as the preparation method and the application thereof, the liposome hydrogel is prepared by taking high-molecular hyaluronic acid and phenylboronic acid as main raw materials, and the liposome hydrogel has microenvironment responsiveness and time-space characteristics of drug release, and can be used for treating osteoarthritis in an environment with active oxygen increase, so that the drug release effect is good, and the drug release effect is good. The functions of early-stage anti-inflammation and continuous cartilage regeneration are achieved by sequentially releasing double drugs, synovitis can be effectively relieved, cartilage regeneration can be promoted, and the compound can be used for preparing drugs for treating osteoarthritis.

The invention provides a preparation method of cereal fermentation broth postbiotics and application of the cereal fermentation broth postbiotics in improvement of systemic chronic inflammation and reduction of cholesterol and low-density lipoprotein, and belongs to the technical field of fermentation engineering. The invention provides a preparation method of cereal fermentation broth metabiotics, which is characterized in that mixed cereals are used as raw materials, anaerobic fermentation is carried out by using compound enzymes and various bacteria, and polysaccharides and proteins in the cereal raw materials can be quickly converted into functional small molecular substances, such as polypeptides, total phenols and total flavonoids. The cereal fermentation broth metagen can inhibit secretion of a macrophage proinflammatory medium, inhibit generation of inflammatory factors of liver, heart and intestinal tissues, and improve activation of adipose tissue macrophages related to body inflammation. After the cereal fermentation liquor is subjected to post-biogen treatment, glucose and lipid metabolism disorder can be effectively improved, liver function damage can be relieved, and the intestinal barrier function can be effectively improved.

The preparation method comprises the following steps: mixing polysaccharide gum with water, carrying out wet ultrafine grinding to obtain an ultrafine polysaccharide gum aqueous solution, and uniformly infiltrating the polysaccharide gum into cellulose or derivatives thereof by adopting high-shear mixing to form micelles; and promoting the micelles to form a honeycomb structure through microwave vacuum drying, and finally spraying ultrapure water atomized by high pressure to the honeycomb micelles and drying to obtain the hydrogel for absorbing grease. The water absorption capacity of the prepared hydrogel reaches 100 times or above, the storage modulus is 1350 Pa or above, grease can be efficiently absorbed, and the hydrogel has wide development prospects in the field of weight-reducing medicine or food.

The invention discloses a green processing technology of sea cucumber powder capable of realizing directional enrichment and improving polysaccharide release rate, and belongs to the field of food processing. The sea cucumber powder is prepared by the following steps: S1, pretreating sea cucumbers; s2, enrichment of nutrient substances of the sea cucumbers; s3, regulating and controlling the particle size of the sea cucumber powder; s4, performing'single 'supercritical treatment; s5, carrying out in-situ ultramicro physical crushing; and S6, performing'dual 'supercritical treatment. Through the design of the gas disperser and the additional arrangement of the second hole disc, the supercritical extraction instrument can perform effective supercritical carbon dioxide extraction on the ultramicro sea cucumber powder, the deodorization of the ultramicro sea cucumber powder is realized, and the eating quality of the ultramicro sea cucumber powder is improved. Moreover, by detecting and regulating the stacking density and the tap density, optimal processing parameters for the ultramicro sea cucumber powder are found, so that the prepared ultramicro sea cucumber powder is high in polysaccharide release rate, good in eating quality and easy for subsequent processing.

The invention discloses a method for simulating small intestine-colon dynamic digestion and glycolysis of polysaccharide-based food, and belongs to the technical field of food detection. The small intestine-colon simulated digestion and absorption system special for the polysaccharide-based food comprises a small intestine digestion simulation system, a sampling and emptying system, a large intestine glycolysis simulation system and a central intelligent control and display system (a pH control system, a temperature control system, a stirring rate control system, a gas path system and a flow rate control system). Aiming at the limitations that an existing human gastrointestinal tract digestion in-vitro simulation system cannot be continuous, is short in period and the like, the in-vivo real digestion and glycolysis physiological environment and process are simulated, intestinal peristalsis waves and digestion and glycolysis of polysaccharide-based food are simulated, automatic sampling can be achieved, generation of glucose in small intestines can be detected on line, and the in-vitro simulation system fits the real human physiological environment.

The invention discloses a rhizoma smilacis glabrae leavening and a preparation method and application thereof in hyperuricemia, and the scheme is as follows: inoculating a lactobacillus fermentation seed solution into a rhizoma smilacis glabrae traditional Chinese medicine stock solution, fermenting for 48-72 hours at 37 DEG C, and freeze-drying to obtain the rhizoma smilacis glabrae leavening; the lactobacillus brevis fermentation seed liquid is prepared by fermenting lactobacillus brevis YM 1301 and lactobacillus plantarum CICC24202, and the lactobacillus brevis YM 1301 and the lactobacillus plantarum CICC24202 are fermented; the lactobacillus fermentation seed liquid accounts for 6-10% of the volume of the rhizoma smilacis glabrae traditional Chinese medicine Results show that after the rhizoma smilacis glabrae is fermented, the contents of total flavone and total polyphenol are increased, and the polysaccharide content is reduced; the rhizoma smilacis glabrae leavening can significantly reduce serum uric acid, urea nitrogen and creatinine levels of HUA rats; the kidney injury caused by hyperuricemia is improved; the increase of inflammatory cytokines such as IL-1beta and TNF-alpha in serum is reduced, and the curative effect is superior to that of unfermented rhizoma smilacis glabrae; the mechanism of reducing uric acid may be by inhibiting the activity of xanthine oxidase in HUA rats and increasing the excretion of uric acid in excrement. The invention provides a solid theoretical reference basis for developing safe and effective uric acid-reducing traditional Chinese medicine large-scale health products.

The invention discloses novel vegetable protein-polysaccharide composite nanoparticle stable powdered oil and a preparation method thereof, and belongs to the technical field of powdered oil preparation. The preparation method of the novel vegetable protein-polysaccharide powdered oil comprises the following steps: adding water into vegetable protein, dispersing, stirring overnight, and hydrating to obtain vegetable protein dispersion liquid; adding water to disperse polysaccharide, stirring overnight and hydrating to obtain a polysaccharide dispersion liquid; mixing the vegetable protein dispersion liquid with the polysaccharide dispersion liquid, adjusting the pH value to be alkaline, heating, stirring, cooling, and adjusting the pH value to be neutral, so as to obtain vegetable protein-polysaccharide composite nanoparticle dispersion liquid; and adding an oil phase, shearing and emulsifying, homogenizing at high pressure, and finally spray-drying. According to the method, the vegetable protein-polysaccharide composite nanoparticles are prepared through the pH shift vegetable protein-polysaccharide mixture, the grease is encapsulated through spray drying, the stability of the grease is improved, the method can also be used for embedding curcumin and other active substances, and a new thought is provided for improving the stability of the active substances.

The invention discloses a ginseng extract rich in rare saponins and preparation and anti-aging application thereof, and belongs to the technical field of oral beauty and skin care products, the ginseng extract is obtained by fermentation treatment of ginseng powder through phytobacterium plantarum, and the preservation number of the phytobacterium plantarum is GDMCC No.64374. The ginseng extract rich in rare saponin is fermented by specific plant lactobacillus, ginsenoside is efficiently converted into CK and F1, various natural plant components such as ginseng polysaccharide are reserved, and a specific synergistic effect is generated. Through verification, the prepared ginseng extract is high in bioavailability, can more effectively inhibit cell inflammation, and can more effectively recover the mitochondrial function of senescent cells and inhibit cell senescence. The preparation method provided by the invention is high in operability and easy to standardize and intellectualize. Compared with a traditional extraction and purification method, the adopted fermentation method is more environmentally friendly and efficient, and large-scale production can be achieved in industrial production.

The invention relates to hydrogel for treating ischemic brain injury and a preparation method thereof. The hydrogel is prepared from the following raw materials: methylacryloylated hyaluronic acid, methylacryloylated gelatin, curcumin loaded HA-PPS (Hydroxypropyl-Polyphenylene Sulfite) nano-micelles and dendrobium polysaccharide loaded sodium alginate microspheres. Through combination of a nanotechnology and an intelligent response material, HA-PPS is adopted to load curcumin and sodium alginate microspheres are adopted to encapsulate dendrobium polysaccharide, so that the drug activity can be more effectively protected, the drug is protected to penetrate through a blood brain barrier and be accurately delivered to a brain injury area, and targeted release of the drug is realized; the anti-oxidation and anti-inflammatory effects are better under the combined action of the curcumin and the dendrobium polysaccharides, and meanwhile, a slow release function is also achieved.

The invention relates to the technical field of cosmetics, and provides a composition containing a dendrobium officinale enzymolysis extract, which is prepared from the following components in percentage by mass: 18 to 22 percent of dendrobium officinale enzymolysis extract, 9 to 11 percent of chitosan oligosaccharide, 6.5 to 7.5 percent of bionic moisturizing enhancer, 0.1 to 0.2 percent of sodium alginate, 0.05 to 0.15 percent of citric acid / sodium citrate buffer pair and 60.4 to 65.4 percent of solvent matrix. By combining low-temperature enzymolysis with a biological purification process, efficient extraction of dendrobium candidum polysaccharides and phenolic substances is realized, dendrophenol oxidation inactivation caused by high temperature can be effectively avoided, hydrochloric acid residues in chitosan oligosaccharide preparation are effectively removed, formula irritation is remarkably reduced, and the dendrobium candidum extract is more suitable for sensitive skin care; the components in the composition have a synergistic effect, the dendrobium officinale enzymolysis extract and the enzymolysis chitosan oligosaccharide form a composite moisturizing network, the moisturizing rate is remarkably increased, the oxidation resistance is remarkably improved, and the composition can be applied to products such as essence, masks and freeze-dried powder.

The invention provides a nitrification inhibitor and a preparation method thereof as well as stable urea and a preparation method thereof, and relates to the technical field of fertilizers. The nitrification inhibitor provided by the invention is prepared from the following components in percentage by mass: 20 to 45 percent of 3, 4-dimethyl pyrazole phosphate (DMPP), 30 to 70 percent of amino acid and the balance of auxiliaries, the auxiliary agent is one or more of polysaccharide, polyvinylpyrrolidone, poloxamer and carbomer. According to the invention, the DMPP and the amino acid are compounded, the amino acid is used as a stabilizer of the DMPP, so that the stability of the DMPP can be remarkably improved, and meanwhile, the polymer additive is used as an adhesive, so that the stability of the DMPP can be further improved. The nitrification inhibitor provided by the invention has excellent stability; the stable urea can be obtained by adopting an endogenous adding mode and adding the stable urea into the urea with relatively low loss, and the stable urea has multiple effects of improving the urea utilization rate, improving the crop quality, improving the soil biological environment, improving the soil fertility and the like.

The preparation method comprises the following steps: S1, crushing cordate houttuynia rhizomes, adding the crushed cordate houttuynia rhizomes into a mixed acid aqueous solution, and carrying out immersion treatment to obtain a cordate houttuynia mixed solution; s2, adjusting the pH value of the herba houttuyniae mixed solution to 4-5, adding pectinase, carrying out primary enzymolysis and enzyme deactivation, adjusting the pH value to 6-7, adding compound enzyme, carrying out secondary enzymolysis and enzyme deactivation, so as to obtain an enzymatic hydrolysate; s3, menthol is added into the enzymatic hydrolysate, water extraction is conducted, and water extract and filter residues are obtained; s4, the filter residues are added into ethyl alcohol, then salicylic acid and diacetyl tartaric acid ester of mono (di) glycerides are added, alcohol extraction and filtering are conducted, and an alcohol extraction solution is obtained; s5, mixing the water extract with the alcohol extract, and performing reduced pressure distillation to obtain the herba houttuyniae extract. According to the method, the extraction rate of polysaccharide and flavone in houttuynia cordata can be effectively increased, and meanwhile, the prepared houttuynia cordata extract has better oxidation resistance and has a good application prospect.

The invention relates to the technical field of adsorbents, in particular to modified sodium alginate as well as a preparation method and application thereof. The modified sodium alginate is prepared from the following raw materials: sodium alginate, an activating agent, a sulfhydrylation reagent, a carboxylic acid compound containing unsaturated double bonds and an initiator. Natural polysaccharide sodium alginate is adopted as a raw material, the natural polysaccharide sodium alginate is wide in source, non-toxic and biodegradable, a functional group carboxyl is introduced into sodium alginate through a thiol-ene click reaction, adsorption active sites on the surface of the modified sodium alginate are increased, methylene blue and ciprofloxacin in water can be effectively adsorbed and removed, and the service life of the modified sodium alginate is prolonged. And after multiple times of cyclic adsorption-desorption, relatively good adsorption performance can be maintained.

The invention belongs to the technical field of catalysts, and particularly relates to an alumina-based catalyst for anthraquinone hydrogenation and a preparation method thereof.The preparation method comprises the following steps that 1, aluminum salt and PVP are added into deionized water, and an aluminum salt mixed solution is obtained; (2) adding ammonium salt and cyclic polysaccharide micromolecules into deionized water to obtain an ammonium salt mixed solution; (3) dropwise adding the aluminum salt mixed solution into the ammonium salt mixed solution while stirring, and performing aging, suction filtration, drying and calcination to obtain an alumina carrier; (4) impregnating the alumina carrier with a palladium salt solution; and (5) drying, roasting and reducing the impregnated alumina carrier to obtain the alumina-based catalyst for anthraquinone hydrogenation. Macromolecular PVP (Polyvinyl Pyrrolidone) and cyclic polysaccharide micromolecules are used as composite template agents for ammonium-aluminum coprecipitation, so that not only is an alumina carrier material with a high specific surface area prepared, but also the loading capacity on palladium is improved, the dispersion of palladium is promoted, and the hydrogenation efficiency is favorably improved.